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Invisible Intersections: Race, Adhd, And The Role Of Disciplinary Actions In Academic Outcomes, Miles Feller

Clinical Psychology Dissertations

Race is a marginalized identity linked to significant achievement gaps for Black and Latino students in the USA (de Bray et al., 2019). These students experience higher rates of exclusionary school discipline (ESD) than White and Asian peers (Aud et al., 2010; de Bray et al., 2019), with suspensions correlating to lower academic performance (Del Toro & Wang, 2022; Wang et al., 2023; Owens & Hinshaw, 2016). Additionally, developmental disabilities like ADHD intersect with these issues; despite narrowing racial disparities in diagnoses (Cénat et al., 2022; Fairman et al., 2020), access to treatment remains uneven (Baglivio et al., 2017; Coker …

Impact Of Perceived Stress And Trait Resilience On Mental Health Outcomes Related To Traumatic Stress Exposure, Ken Safley

Clinical Psychology Dissertations

Traumatic stress exposure is common and associated with a range of adverse psychological outcomes, including anxiety, depression, and posttraumatic stress disorder (PTSD). These effects are cumulative, with increased exposure linked to greater psychological distress. However, there is considerable variability in how individuals respond to trauma, suggesting the influence of cognitive and dispositional factors. Cognitive models of PTSD highlight the role of stressor appraisals in the development of psychopathology, while individual differences in protective factors, such as trait resilience, may buffer these effects. The present study investigated whether perceived stress mediates the relationship between trauma exposure and psychological outcomes, and whether …

Evidence And Consensus-Based Imaging Guidelines In Birdshot Chorioretinopathy: Multimodal Imaging In Uveitis (Muv) Taskforce Report 8, Jose S. Pulido

Wills Eye Hospital Papers

PURPOSE: To develop consensus-based imaging guidelines for diagnosing and monitoring birdshot chorioretinopathy (BSCR).

DESIGN: Consensus-based approach guided by literature and an expert committee using a nominal group technique (NGT).

METHODS: An expert committee of 5 international uveitis specialists reviewed 15 well-documented representative BSCR cases with comprehensive imaging data. Cases with active and inactive disease were included. Imaging, including color fundus photography (CFP), fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), optical coherence tomography (OCT), fundus autofluorescence (FAF), and OCT angiography (OCTA) were reviewed. Using a structured NGT approach, consensus-based recommendations were developed for specific disease characteristics, biomarkers of activity, and …

A Core Curriculum For Sociology In Undergraduate Medical Education (2nd Edition), Tracey Collett, Kathleen Kendall, Jeni Harden

Peninsula Medical School

No abstract provided.

Expert Opinion On Clinical Presentation, Diagnosis And Treatment Of Infantile Onset Pompe Disease: A Delphi Study In Türkiye, Eki̇n Özsaydi Aktaşoğlu, Asli İnci̇, Ridvan Murat Öktem, Gürsel Bi̇beroğlu, İlyas Okur, Fati̇h Süheyl Ezgü, Fi̇li̇z Başak Cengi̇z Ergi̇n, Abdurrahman Akgün, Nur Arslan, Hali̇l İbrahi̇m Aydin, Ayşe Ergül Bozaci, Mahmut Çoker, Fatma Tuba Emi̇noğlu, Meli̇ke Ersoy, Emi̇ne Göksoy, Banu Kadioğlu Yilmaz, Mehtap Kağnici, Mustafa Kiliç, Nesli̇han Önenli̇ Mungan, Burcu Öztürk Hişmi̇, Pembe Soylu Üstkoyuncu, Ayşegül Tokatli, Ayşe Çi̇ğdem Aktuğlu Zeybek, Berrak Bi̇lgi̇ner Gürbüz, Sevi̇l Dorum, Di̇lek Güneş, Çi̇ğdem Seher Kasapkara, Sebi̇le Kilavuz, Erdoğan Soyuçen, Peli̇n Teke Kisa, Özlem Ünal Uzun, Fatma Derya Bulut, Songül Gökay, Selen Has Özhan, Deni̇z Kor, Aynur Küçükcongar Yavaş, Fi̇gen Özçay, Yilmaz Yildiz, Harun Yildiz, Leyla Tümer

Turkish Journal of Medical Sciences

Background/aim: Pompe disease (acid maltase deficiency, glycogen storage disease type II, OMIM #606800) is an autosomal recessive disorder characterized by lysosomal acid-α-glucosidase deficiency. The infantile-onset type of the disease is mainly characterized by cardiomegaly, hypotonia, and a high mortality rate. This study aimed to create a national consensus about infantile-onset Pompe disease (IOPD) to raise awareness among clinicians and standardize diagnosis and treatment approaches in Türkiye.

Materials and methods: The Gazi University Division of Metabolic Diseases and Nutrition developed this expert opinion consensus and expanded it to include metabolism specialists across Türkiye. A systematic literature review was performed, and the …

A Meta-Analysis Of The Effects Of Probiotic Supplementation On Type 2 Diabetes Parameters, Mostefa Naimi, Zineb Benmechernene, Méghit Boumédiène Khaled

Baghdad Science Journal

We aimed to assess the effect of probiotic supplementation on type 2 diabetes (T2D) related variables. Randomized controlled trials (RCTs) were systematically searched from PubMed, Springer-link and Scopus data bases published between 2016 and 2020. Collected studies were independently assessed for eligibility, data extracted and evaluated for risk of bias. Statistical analysis was performed using RevMan 5.4.1. The effects of probiotics were assessed for: body mass index (BMI), fasting blood glucose (FBG), glycated hemoglobin (HbA1c), homeostasis, model assessment-estimated insulin resistance (HOMA-IR), insulin, triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), systolic blood pressure (SBP), diastolic …

Correction: Rationale For A 4-Month, Parallel-Group, Randomized Controlled Trial To Assess The Feasibility And Efficacy Of A Remotely Delivered Exercise Training Intervention For Hispanics/Latinos With Multiple Sclerosis (Ferla Ms), Victoria A Flores, Stephanie L Silveira, David X Marquez, Dominique Kinnett-Hopkins, Augusto Miravalle, Fabian Sierra-Morales, Zulma Hernández-Peraza, Robert W Motl

Faculty, Staff and Student Publications

No abstract provided.

A Study On Covid-19 Outbreak In Cook County Of Illinois, Suraj Powar

Research Papers

This study presents a mathematical model developed to better understand the transmission dynamics of COVID-19 and evaluate the effectiveness of different public health strategies. The model, called SEQIRD, includes of the disease such as exposure, quarantine, infection, recovery, and death. Using real case and death data from Cook County, Illinois, the model closely fits observed trends and captures both pre and post-lockdown dynamics with high accuracy.

Our results show that early intervention significantly reduces total infections, with lockdown imposed even a few days earlier preventing thousands of cases. Through sensitivity analysis, we also identify that parameters such as transmission rate, …

Emt Vision, Logan Calder, Grant Johnson, John Alvarado, Jack Landers

Computer Science and Engineering Senior Theses

Augmented Reality (AR) has demonstrated considerable promise for future mobile technologies, offering the ability to overlay crucial information within a user’s vision while they can still maintain awareness of the surrounding environment. Similarly, Artificial Intelligence (AI) is an increasingly influential technology with significant potential to revolutionize the medical field. Its ability to rapidly learn and adapt to specific tasks makes it particularly promising for supporting paramedics during emergency calls. AI can efficiently analyze real-time data and present it in a concise, actionable format, enhancing decision making in critical situations.

Given the potential of these technologies, we have developed a smart …

Utilization Of Bixin-Loaded Polycaprolactone Nanoparticles To Ameliorate E-Cigarette-Induced Damage To Human Bronchial Epithelial Cells, Sophia R. Claymore

USF Tampa Graduate Theses and Dissertations

Electronic cigarettes (e-cigs) have increased in popularity and usage over the last few decades. E-cigs are generally composed of a liquid containing nicotine flavoring chemicals, a battery, a vaporization chamber, and a coil that heats the liquid upon inhalation of the mouthpiece. E-cigs were initially introduced as a healthy alternative to cigarette smoking. However, recent research has demonstrated that e-cigs elicit comparable cytotoxic and dangerous effects to conventional cigarettes. Bixin has been introduced in recent research as a candidate for therapeutic applications due to its innate anticancer, antioxidative, and anti-inflammatory characteristics. Nanoparticles (NPs) have emerged over the past few decades …

An Application Of A Positive Psychology Intervention To Promote The Well-Being Of Children With Cancer, Jenna Barnes

USF Tampa Graduate Theses and Dissertations

The psychological impact of pediatric cancer and cancer treatment is not well understood. Although there is evidence to suggest that pediatric cancer may negatively impact youth’s mental health and psychological functioning, other research suggests that the mental health of children with cancer is similar to that of healthy peers. Traditional psychological interventions have been used to reduce symptoms of psychopathology among children with cancer. However, less is known about the subjective well-being of children with cancer and evidence-based, positive psychology interventions to promote the subjective well-being of this population. Thus, this study sought to address this gap in the literature …

Untangling The Threads Of Hope: A Qualitative Media Analysis Of Discourse Relating To Futures For Sickle Cell Disease, Amanda R. Malerba

USF Tampa Graduate Theses and Dissertations

Sickle cell disease (SCD) is the most common inherited blood disorder worldwide, with a disproportionate burden on people of African ancestry. Life with this illness is characterized by chronic physical pain, overlapping health conditions, and often early death. In the United States, the physical symptoms of the disease are frequently compounded by experiences of racial inequality and oppression embedded in the medical system that contribute to detrimental outcomes. Because of the complex biocultural web of factors contributing to the suffering of people with SCD, much of the anthropological scholarship surrounding this illness prioritizes deconstructing systems of power, oppression, and inequality. …

57 Elmhurst Llc V. Terada

All Decisions

The court dismissed the landlord's holdover petition alleging illegal sublet, unauthorized alterations (partition), and failure to install carpeting. The illegal sublet claim was dismissed for lack of proof of vacation or financial arrangement. The alteration and carpeting claims were dismissed due to waiver, as prior and current landlords implicitly consented by failing to object despite clear visibility and opportunities over a long tenancy. The tenant's reasonable accommodation defense for carpeting was not established.

Protocol For Assessing Mobilization Of Peritoneal B Cells To The Pre-Metastatic Omentum In An Orthotopic Mouse Model Of Ovarian Cancer, Wonjae Lee, Hironari Akasaka, Honami Naora

Faculty, Staff and Student Publications

The omentum is a visceral adipose tissue that undergoes dynamic immunological changes prior to and following metastasis. Here, we present a protocol for assessing the mobilization of peritoneal B cells to the pre-metastatic omentum in a mouse ovarian cancer model. We describe steps for isolation and adoptive transfer of peritoneal donor B cells and their detection in the omentum of recipient mice. This protocol could be utilized to study the mobilization of peritoneal B cells to the omentum in other pathological contexts. For complete details on the use and execution of this protocol, please refer to Lee et al.

Protocol For Establishing Genetically Engineered Murine Lung Organoids Mimicking Cell Plasticity And Regeneration, Bongjun Kim, Jae-Il Park

Faculty, Staff and Student Publications

Lung endothelial cells (LuECs) play crucial roles in lung regeneration and support lung organoids (LOs). However, detailed guidelines for LO culture using LuECs have not been reported yet. Here, we present an efficient protocol for generating and culturing murine LOs that mimic regeneration. We describe steps for the isolation of LuECs and lung epithelial cells, followed by LO culture. We also describe how to establish genetically engineered LOs using viral transduction. For complete details on the use and execution of this protocol, please refer to Kim et al.

Characterization And Clinical Implications Of P53 Dysfunction In Patients With Myelodysplastic Syndromes, Matteo Zampini, Elena Riva, Luca Lanino, Elisabetta Sauta, Rita Antunes Dos Reis, Rosa Maria Andres Ejarque, Giulia Maggioni, Alberto Termanini, Alessandra Merlotti, Alessia Campagna, Lorenzo Dall'olio, Austin Kulasekararaj, Michela Calvi, Clara Di Vito, Arturo Bonometti, Daoud Rahal, Giorgio Croci, Emanuela Boveri, Umberto Gianelli, Maurilio Ponzoni, Rossella Caselli, Serena Albertazzi, Gabriele Todisco, Marta Ubezio, Laura Crisafulli, Alessandro Frigo, Enrico Lugli, Ettore Mosca, Pamela Acha, Serena Ghisletti, Francesco Nicassio, Armando Santoro, Maria Diez-Campelo, Francesc Solé, Lionel Ades, Uwe Platzbecker, Valeria Santini, Pierre Fenaux, Torsten Haferlach, David Sallman, Guillermo Garcia-Manero, Domenico Mavilio, Daniel Remondini, Gastone Castellani, Saverio D'Amico, Amer M Zeidan, Rami Komrokji, Shahram Kordasti, Francesca Ficara, Matteo Giovanni Della Porta, Calr Consortium

Faculty, Staff and Student Publications

Purpose: Tumor Protein 53 (p53) expressed from gene TP53 is a seminal tumor suppressor. We aimed to characterize mutational and nonmutational mechanisms of p53 dysfunction in myelodysplastic syndromes (MDS) and to investigate their clinical effect.

Patients and methods: We analyzed a cohort of 6,204 patients with MDS and subsets of patients with available information on RNA sequencing of tumor cells (n = 109), high-dimensional phenotype of immune cells (n = 77), and multiomics analysis (RNA sequencing and proteomics) on single cells (n = 15). An independent validation was performed on 914 patients.

Results: Biallelic TP53 inactivation was a powerful driver …

Usp37 Counteracts Hltf To Protect Damaged Replication Forks And Promote Survival Of Brca1-Deficient Cells And Parp Inhibitor Resistance, Mengfan Tang, Siting Li, Ziqiang Zhu, Chao Wang, Shuai Ding, Huimin Zhang, Min Huang, Sarah Keast, Zhen Chen, Ling Yin, Litong Nie, Dan Su, Xu Feng, Junjie Chen

Faculty, Staff and Student Publications

Poly(ADP-ribose) polymerase inhibitors (PARPi) have greatly improved survival of cancer patients harboring BRCA1 mutations. However, therapy resistance develops via either restoration of homologous recombination or replication fork stabilization. Therapeutic targets to overcome PARPi resistance are critically needed. We identified the deubiquitinase USP37 as a key determinant of PARPi toxicity in BRCA1-deficient cells via whole-genome CRISPR screens. USP37 ablation enhanced PARPi sensitivity in BRCA1-deficient cells and also overcame PARPi resistance due to 53BP1 loss. USP37 interacts with and deubiquitinates replication protein A (RPA) at stalled replication forks to limit excessive RPA accumulation, progressive RPA exhaustion, and the conversion of RPA-coated single-stranded …

Protocol To Analyze Trna And Rrna Processing Using Biotin-Labeled Probes, Sseu-Pei Hwang, Katherine Barondeau, Catherine Denicourt

Faculty, Staff and Student Publications

Mature tRNAs and rRNAs are derived from larger precursor transcripts through intricate endo- and exonuclease processing steps. Here, we present a protocol to analyze rRNA and tRNA processing using total RNA extracted from human cells. We describe steps for separating RNA by denaturing electrophoresis, followed by northern blotting. We detail procedures for detecting pre-rRNA intermediates or specific tRNA species using biotin-labeled probes imaged via fluorescence or chemiluminescence. This non-radioactive, high-sensitivity assay enables the investigation of rRNA and tRNA expression dynamics. For complete details on the use and execution of this protocol, please refer to Hwang et al.

Turkish Translation, Validity, And Reliability Of The European Organization For Research And Treatment Of Cancer Quality Of Life-High Dose Chemotherapy29 In Patients Undergone Hematopoietic Stem Cell Transplantation, Vesi̇le Yildiz Kabak, Sevi̇lay Karahan, Eli̇fcan Aladağ Karakulak, Tüli̇n Düger, Songül Atasavun Uysal, Fulya İpek-Erdem, Hakan Göker

Turkish Journal of Medical Sciences

Background/aim: Our aim was to investigate psychometric properties of the Turkish version of the European organization for research and treatment of cancer quality of life-high dose chemotherapy29 (EORTC QLQ-HDC29) in patients treated with hematopoietic stem cell transplantation (HSCT).

Materials and methods: Patients between the ages of 18 and 65 years and undergone HSCT were included. The European organization for research and treatment of cancer quality of life questionnaire–cancer30 the Eastern cooperative oncology group performance score, and the functional assessment of cancer therapy–bone marrow transplant were used to determine convergent validity. Reliability was assessed through the calculation of Cronbach’s alpha and …

Effects Of Lumbar Stabilization Exercises On Serum Biomarker Levels And Clinical Outcomes In Lumbar Disc Herniation: A Subgroup Analysis Of A Randomized Controlled Trial, Bi̇rgül Morkoç, Onur Aktan, Gamze Sönmez, Ebru Bodur, Jale Karakaya, Bayram Kaymak, Sevi̇l Bi̇lgi̇n

Turkish Journal of Medical Sciences

Background/aim: The aim of our study was to investigate the effectiveness of lumbar stabilization exercises on serum biomarker levels and clinical outcomes in lumbar disc herniation (LDH) patients with and without neurological deficit.

Materials and methods: 40 patients with neurological deficits (WND) and 34 patients without neurological deficits (WOND) diagnosed with LDH were included in this study. The patients WND and WOND were randomized into stabilization exercises (SE) and general exercises (GE) groups. Stabilization exercises or general exercises were applied for six weeks. Serum levels of tumor necrosis factor alpha (TNF-α), interleukin (IL)-1β, IL-6, IL-4, beta-endorphin (BE), anandamide (AEA), and …

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Effectiveness Of Distal Versus Proximal Greater Occipital Nerve Pulsed Radiofrequencyin Migraine Management: A Prospective Randomized Controlled Trial, Gülçi̇n Babaoğlu, Şükri̇ye Dadali, Ülkü Sabuncu, Erkan Yavuz Akçaboy, Şeref Çeli̇k, Mustafa Yemli̇ha Ayhan, Yağmur Can Dadakçi, Mustafa Cem Yilmaz, Şazi̇ye Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: We aimed to evaluate the effectiveness of distal versus proximal greater occipital nerve (GON) pulsed radiofrequency (PRF) treatments in patients with episodic or chronic migraine.

Materials and methods: In this prospective, randomized controlled study, sixty participants were randomized to either distal GON PRF (n= 30) or proximal GON PRF (n = 30). Migraine related assessments were conducted at the baseline and at the first, second, and third month.

Results: Baseline characteristics indicated a higher migraine burden in the proximal group, including increased monthly headache frequency (15.0 vs. 9.5 attacks, p = 0.007). Both groups experienced significant reductions in headache …

Short-Term Efficacy And Safety Of Nondamaging Retinal Laser Therapy For Retinitis Pigmentosa-Associated Cystoid Macular Edema, Seda Çevi̇k Kaya, Mehmet Çitirik, Mevlüt Yilmaz, Eyüpcan Şensoy

Turkish Journal of Medical Sciences

Background/aim: To evaluate the short-term efficacy and safety of nondamaging retinal laser therapy (NRT) for retinitis pigmentosa-associated cystoid macular edema (RP-CME) and analyze anatomical and functional outcomes.

Materials and methods: A retrospective case series of 40 eyes from 30 patients with RP-CME was conducted. The patients underwent NRT using a PASCAL laser system with endpoint management (EpM) software. Central macular thickness (CMT) and best-corrected visual acuity (BCVA) were assessed at baseline and 2 months posttreatment. Long-term follow-up data, including recurrence rates were also reviewed.

Results: At the 2-month follow-up, NRT significantly reduced mean CMT by 79.7 μm (p < 0.001) and improved BCVA by 0.10 LogMAR (p < 0.001). Complete resolution of CME was observed in 30% of the eyes, while 52.5% experienced recurrence within 6 months. Unilateral cases exhibited greater CMT reductions than bilateral cases (p < 0.05). No retinal damage from the laser was observed. The long-term sustainability of these effects remains unclear, and repeated treatments have not yet been assessed.

Conclusion: NRT …

Il-40 Levels In Treatment-Naïve And Methotrexate-Treated Rheumatoid Arthritis Patients, Hamdi̇ Oğuzman, Mete Pekdi̇ker

Turkish Journal of Medical Sciences

Background/aim: Rheumatoid arthritis (RA) is an autoimmune disease that is characterized by persistent inflammation and progressive damage to the joints. In this study, it was aimed to explore the role of interleukin (IL)-40, a newly discovered cytokine, in the pathogenesis of RA. We also aimed to investigate the relationship between IL-40 and other cytokines such as IL-4, transforming growth factor (TGF)-β1 and tumor necrosis factor (TNF)-α.

Materials and methods: This single-center, cross-sectional study included 87 participants divided into three groups: healthy controls (n = 29), newly diagnosed RA patients (n = 29), and RA patients with remission under methotrexate (MTX) …

Janus Kinase Inhibitors In Localized Scleroderma: A Systematic Literature Review, Seher Şener, Yusuf Zi̇ya Şener, Ezgi̇ Deni̇z Batu, Alper Sari, Ali̇ Akdoğan

Turkish Journal of Medical Sciences

Background/aim: Reports on the use of Janus kinase (JAK) inhibitors in the treatment of localized scleroderma are increasing in the literature. In this review, we examined the published studies regarding the use of JAK inhibitors in patients with localized scleroderma.

Materials and methods: We searched MEDLINE and Scopus for articles on patients with localized scleroderma treated with JAK inhibitors. The search included articles from the inception of these databases through August 1st, 2024.

Results: Our literature search showed 11 articles describing 17 patients with localized scleroderma treated with JAK inhibitors. Generalized morphea (47.1%) was the most common type of localized …

Effectiveness Of Ultrasonography-Guided Periforaminal Oxygen-Ozone Therapy In Chronic Low Back Pain, Esra Ülgen Kiratlioğlu, Kutay Tezel, Eda Gürçay

Turkish Journal of Medical Sciences

Background/aim: Treatment of chronic low back pain (LBP) includes various minimally invasive image-guided interventional techniques. The aim of this study, which was planned based on the idea that periforaminal oxygen-ozone (O2-O3) gas application with ultrasonography (USG) could be an alternative treatment option, was to compare the therapeutic efficacy of USG-guided periforaminal ozone infiltration (PFOI) or transforaminal epidural steroid injection (TFESI) in patients with chronic radicular LBP on pain, disability, and quality of life (QoL).

Materials and methods: A total of 50 patients were randomly divided into 2 groups of 25 patients each underwent PFOI by USG or TFESI via fluoroscopy. …

Prognostic Factors For Long-Term Outcomes Of Unilateral Atrophic Kidneys In Adult Patients: A Single-Center Retrospective Cohort Study, Zülal İstemi̇han, Ahmet Burak Di̇ri̇m, Ali̇ Riza Uçar, Ceren Bağriaçik, Gamze Kemeç, Şafak Mi̇ri̇oğlu, Seda Şafak, Vafa Suleymanova, Özgür Akin Oto, Ayşe Serra Artan, Alaatti̇n Yildiz, Aydin Türkmen, Hali̇l Yazici

Turkish Journal of Medical Sciences

Background/aim: Unilateral atrophic kidney (UAK) could be related to many etiologies that can cause chronic kidney disease in adults. There is limited data on the long-term outcome of adults with UAK in the literature.

Materials and methods: This study included 199 adult patients with UAK. The etiology, baseline clinical/laboratory, and radiological findings were evaluated. Composite primary outcomes (CPO) (chronic kidney disease stage 5 or doubling of serum creatinine) and secondary outcomes (new-onset proteinuria (>0.5 g/day or g/g) or >50% increase in proteinuria level according to baseline, mortality, and nephrectomy requirement during follow-up) were evaluated in 166 patients with at …

One-Year Clinical Follow-Up Of Granulomatous Lymphadenitis Diagnosed Viaebus-Tbna In A Tuberculosis-Endemic Region, Hasret Gi̇zem Kurt, Ayperi̇ Öztürk, Melahat Uzel Şener, Fi̇gen Öztürk Ergür, Zeynep Ti̇lbe Saymaz Guvanjov, Aydin Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Granulomatous lymphadenitis is not a specific clinical diagnosis. In regions where tuberculosis (TB) is endemic, differentiating between various diseases presenting with granulomatous lymphadenitis poses a significant clinical challenge. This study aims to evaluate the etiological distribution of underlying conditions and to assess diagnosis changes observed during at least one year of follow-up in patients diagnosed with granulomatous lymphadenitis through endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).

Materials and methods: A total of 4711 patients were included in the study, and 9353 lymph node samples were collected. Granulomatous lymphadenitis was identified in 791 patients, from whom 1505 lymph node samples were …

Investigation Of The Relationship Between Triglyceride Glucose Index And Metabolic And Hematological Parameters In Obese Individuals, Özge Baş Aksu, Feri̇de Özkara, Rifat Emral, Volkan Genç, Demet Çorapçioğlu, Mustafa Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: This research examined the association between the triglyceride-glucose (TyG) index and metabolic, hepatic, and hematologic variables in a population of severely obese subjects, with a focus on the assessment of glycemic control.

Materials and methods: This retrospective study included 315 adult patients with a body mass index (BMI) ≥ 35 kg/m² who were evaluated for bariatric surgery. Participants were grouped according to HbA1c levels: those with HbA1c ≥ 6.5% and those with HbA1c < 6.5%. TyG, atherogenic index of plasma (AIP), fibrosis-4 (FIB-4), aspartate aminotransferase-to-platelet ratio index (APRI), and hematological inflammation markers were assessed and compared between groups. To investigate associations, correlation and regression analyses were conducted.

Results: Individuals with HbA1c ≥ 6.5% had significantly higher TyG, AIP, APRI, and FIB-4 values than those with lower HbA1c. The TyG index showed a strong …

Medicolegal Evaluation Of Pediatric Patients With Injection Neuropathy, Hizir Asliyüksek, Caner Beşkoç, Ömer Faruk Şi̇mşeker, Ni̇han Hande Akçakaya, Adem Karbuz

Turkish Journal of Medical Sciences

Background/aim: Injection neuropathy (IN) is a rare but preventable form of iatrogenic nerve injury, particularly affecting the sciatic nerve when intramuscular injections are administered incorrectly. While IN is uncommon in high-income countries, it remains a sig- nificant public health issue in Türkiye, especially in pediatric populations. The aim of this study is to evaluate pediatric IN cases referred to the Council of Forensic Medicine and highlight medicolegal aspects to inform clinical and legal preventive strategies.

Materials and methods: We retrospectively analyzed 67 pediatric cases (age range: 1–17 years; mean age: 10.5 years; 57 boys, 10 girls) referred to the Council …