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Cultivating The Wild: Strategies For Entrepreneurs Navigating Niche And Specialty Food Markets, Trey Malone, Courtney F. Cooper

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Introduction Consumer demand for authenticity and sustainability in food systems is growing, creating both opportunities and challenges for entrepreneurs in niche and specialty markets. While wild-foraged and hunted foods are often perceived as more "natural" and sustainable, attempts to scale these products through farming may compromise their perceived authenticity.Methods To explore these dynamics, we conducted discrete choice experiments with a nationally representative sample of 1,039 U.S. consumers. Participants evaluated their willingness to pay (WTP) for salmon, venison, and morel mushrooms, presented in both wild-foraged/hunted and farm-raised forms.Results Consumers exhibited strong preferences for wild versions of all three products, with average …

Indirect Genetic Effects Among Neighbors Promote Cooperation And Accelerate Adaptation In A Small-Scale Human Society, Jordan S. Martin, Bret Beheim, Michael Gurven, Hillard Kaplan, Jonathan Stieglitz, Benjamin C. Trumble, Paul Hooper, Daniel K. Cummings, Daniel Eid Rodriguez, Adrian V. Jaeggi

ESI Publications

Explaining the rapid evolution of human cooperation and its role in our species’ biodemographic success remains a major evolutionary puzzle. To address this challenge, we tested a social drive hypothesis, which predicts that social plasticity and social selection in human groups cause indirect genetic effects that accelerate the adaptation of fitness, promoting population growth via feedback between the environmental causes and evolutionary consequences of cooperation. Using Bayesian multilevel models to analyze fertility data from a small-scale society, we demonstrate that density- and frequency-dependent indirect genetic effects on fitness promote the evolution of cooperation among neighboring women, increasing the rate of …

A Workplace Posture Initiative To Reduce Work-Related Musculoskeletal Disorders, Carrie Isaac

All Doctor of Nursing Practice (DNP) Scholarly Projects

Problem: Work-related musculoskeletal disorders (WRMSDs) are a leading cause of occupational injury and discomfort in industrial workplaces. Although an ergonomic program existed at the project site, a formalized process to detect postural misalignments early had not been established. Relying on employee self-reporting, delayed intervention, and limited opportunities to prevent injuries before they progress.

Aim of the Project: A proactive posture screening program using PostureScreen® was implemented to identify postural deviations that could contribute to WRMSDs. Emphasis was placed on supporting employees through early awareness of posture-related issues and evaluation of alignment improvements following individualized intervention.

Review of the Evidence: Evidence …

Protective Multi-Stressor Interactions In The Anthropocene: Key Considerations For Investigating Cross-Tolerance In A Conservation Context, Essie M Rodgers, Simone Baldanzi, Michael Collins, W Wesley Dowd, Lauric Feugere, Giovanna Mottola, Fanny Vermandele, Daniel F Gomez Isaza

School of Biological and Marine Sciences

In the Anthropocene, species are increasingly faced with multiple stressors that are more severe and less predictable than before. While multiple stressors often interact to affect organisms negatively, sometimes these interactions can be beneficial, enhancing resilience through cross-protection. Cross-protection interactions occur when exposure to one stressor, such as elevated temperature, enhances an organism’s tolerance to a different stressor, like hypoxia, through shared protective mechanisms or signaling pathways. Understanding the potential for cross-protection to combat rapid and diverse environmental change is crucial for conservation, as it potentially alters the predicted consequences of such change. Here, we outline 10 key considerations for …

Optimal Treatment Duration In Metastatic Renal Cell Carcinoma Patients Responding To Immune Checkpoint Inhibitors: Should We Treat Beyond Two Years?, Alexander Decruyenaere, Gennigens Christine, Rottey Sylvie, Laenen Annouschka, Emmanuel Seront, Els Everaert, Philip R Debruyne, Heidi Van Den Bulck, Julie Bastin, Verbiest Annelies, Christof Vulsteke, Peter Schatteman, Daisy Luyten, Sandrine Aspeslagh, Nieves Martinez-Chanza, Marlies De Bock, Thomas Meyskens, Jolanda Verheezen, Barbara Brouwers, Benoit Beuselinck

School of Nursing and Midwifery

BACKGROUND AND PURPOSE: Optimal treatment duration is unknown in metastatic renal cell carcinoma (mRCC) responding to immune checkpoint inhibitors (ICPIs). Prolonged treatment can lead to late toxicity, burden for day clinics and financial impact.

PATIENTS AND METHODS: This multicenter retrospective study included mRCC patients responding to ipilimumab/nivolumab in first-line or nivolumab in later lines, who were treated for at least 21 months and did not stop for toxicity. Progression-free survival (PFS), overall survival (OS), and cancer-specific survival (CSS) were modeled non- and semi-parametrically. The effect of elective ICPI discontinuation (i.e. treatment interruption at the clinician's discretion) between 21 and 25 …

Description Of The Combined Evidence-Based, Theory-Based And Person-Based Approaches Used To Develop A Behavioural Intervention Package To Support Non-Allergist Healthcare Workers To Remove Incorrect Penicillin Allergy Records From Medical And Surgical Adult Inpatients In A Uk Hospital, Neil Powell, Mathew Upton, Bridie Kent, Jonathan Sandoe, Sarah Tonkin-Crine

School of Biomedical Sciences

Objectives To develop a behavioural intervention package to support non-allergist healthcare workers (HCWs) to remove incorrect penA records from medical and surgical adult inpatients. This paper describes the development of the penicillin allergy de-labelling (PADL) intervention and the implementation intervention that will support non-allergist-delivered PADL. Design We combined evidence-based, theory-based and person-based approaches. Qualitative research with healthcare professionals and patients explored barriers and enablers to implementation of the proposed PADL pathway. Key intervention design objectives and the key features of the implementation intervention required to achieve each objective were then developed and captured as guiding principles. We produced a logic …

Unveiling Spatial Heterogeneity In Medulloblastoma: A Multi-Omics Analysis Of Cellular State And Geographical Organization, Jiankang Li, Hailong Liu, Ziwei Wang, Jiao Zhang, Xuan Chen, Craig Daniels, Xiaochong Wu, Olivier Saulnier, Hiromichi Suzuki, Pasqualino De Antonellis, Alexandra Rasnitsyn, Winnie Ong, Evan Y Wang, Liam D Hendrikse, Yu Su, Yu Tian, Dongming Han, Ruohan Wang, Jialin Mo, Fei Liu, Kaiwen Deng, Dongyang Wang, Zhaoyang Feng, Yifei Jiang, Yanong Li, Yuting Ma, Zijia Liu, Meiyu Li, Peiyi Tian, Yanfeng Shi, Yong Jiang, Tao Yang, Shouwei Li, Jianfeng Liang, Jingchuan Wu, Ying Wang, Wanjing Zou, Yina Jiang, Lusheng Wang, Fang Chen, Xin Jin, Shuaicheng Li, Xiaoguang Qiu, Chunde Li, Ya Gao, Yujie Tang, Michael D Taylor, Tao Jiang

Faculty, Staff and Students Publications

Background: Despite numerous studies on medulloblastoma (MB) cell heterogeneity, the spatial characteristics of cellular states remain unclear.

Methods: We analyze single-nucleus and spatial transcriptomes and chromatin accessibility from human MB spanning four subgroups, to identify malignant cell populations and describe the spatial evolutionary trajectories. The spatial copy number variations (CNVs) patterns and niches were analyzed to investigate the cellular interactions.

Results: Three main malignant cell populations were identified, including progenitor-like, cycling, and differentiated populations. Gene signatures of cell populations strongly correlate to clinical outcomes. These tumor cell populations are geographically organized as stem-like and mature regions, highlighting their spatially heterogeneous …

Systematic Review Of Parkinsonism In Cerebrotendinous Xanthomatosis, Jennifer Hanson, Penelope E Bonnen

Faculty, Staff and Students Publications

Background: Cerebrotendinous Xanthomatosis (CTX) is a rare, inherited metabolic disease caused by pathogenic variants in CYP27A1. The clinical presentation of this progressive disease includes cognitive deficits, ataxia, peripheral neuropathy, and pyramidal signs, as well as bilateral cataracts and tendon xanthomas. In some cases, CTX also includes parkinsonism. The goals of this study are to develop a data source that provides improved characterization and awareness of parkinsonism in CTX.

Methods: We conducted a systematic review of the literature according to PRISMA guidelines to identify all published individuals diagnosed with CTX and parkinsonism. Clinical signs, imaging findings and treatment response to …

Long-Term Testosterone Pellet Insertion In Women With Low Libido Shows No Evidence Of Erythrocytosis And A Minimal Side Effect Profile, Beatriz S Hernandez, Gal Saffati, Katherine A Lowrey, Amit Reddy, Bridget S Park, Jeffrey J Song, Gabrielle Lyon, Mohit Khera

Faculty, Staff and Students Publications

Background: Testosterone therapy for low libido in women has become increasingly prevalent in recent years. While numerous testosterone formulations exist and have been studied in women, there has been little data assessing the safety and efficacy of subcutaneous testosterone pellet use in this population. The primary objective of this study is to understand the biochemical effects and side effect profile of female patients who underwent testosterone pellet insertion in a clinical practice.

Methods: A retrospective chart review of female patients who underwent testosterone pellet insertion from 2009 to 2022 was undertaken. Women taking 75 and 100 mg testosterone pellets were …

Integrating Circulating Tumor Dna Into Clinical Management Of Colorectal Cancer: Practical Implications And Therapeutic Challenges, Nikhil Vojjala, Viktoriya Gibatova, Raj N Shah, Sakshi Singal, Rishab Prabhu, Geetha Krishnamoorthy, Karen Riggins, Nagaishwarya Moka

Faculty, Staff and Students Publications

The American Cancer Society estimates that over 152,000 new cases of colorectal cancer (CRC) were diagnosed in 2024, with more than 105,000 cases affecting the colon and 46,000 involving the rectum. CRC remains the second leading cause of cancer-related deaths in the United States, with an estimated 53,010 deaths in 2024. In the era of precision medicine, which incorporates molecular and environmental information into clinical decision-making, identifying patients harboring a deficiency in Deoxyribonucleic acid (DNA) repair allowed for targeted immunotherapies and significantly reduced CRC-related mortality. A significant advancement in this domain is the application of liquid biopsy, which has emerged …

2020-12-08 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2021-03-09 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2021-04-06 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Efficacy And Safety Of Dapagliflozin In Patients Hospitalized With Covid-19 With And Without Type 2 Diabetes: A Prespecified Analysis Of The Dare-19 Randomized Trial, Mohammad Abdel Jawad, Ali Javaheri, Et Al.

2020-Current year OA Pubs

BACKGROUND: Although several previous studies tested SGLT2 inhibitors in the setting of an acute, non-cardiovascular illness, detailed information on their efficacy and safety among participants with and without type 2 diabetes (T2D) from double-blind randomized trials is lacking. In this secondary prespecified analysis of the Dapagliflozin in Respiratory Failure in Patients with COVID-19 (DARE-19) trial, we sought to evaluate the safety and efficacy of initiating dapagliflozin during acute illness with COVID-19 in patients with and without T2D.

METHODS: The DARE-19 trial randomized 1250 patients hospitalized with COVID-19 and cardiometabolic risk factors to dapagliflozin or placebo. T2D was present in 636/1250 …

Precision Medicine And Beyond: Evolving Roles Of Targeted Therapy, Immunotherapy, And Artificial Intelligence In Oncology, Linwei Li, Anika Doppalapudi, Jennifer Escamilla, Annu Karithara, Christine Pham, Angel Phillip, Sriya Gullapalli, Lois Baldado, Arjun Bellamkonda, Daniela Gonzalez, Amin Ibrahim, David Sta. Maria, Kaitlyn Ybanez, Hugo Zamarron, Shizue Mito

School of Medicine Publications

Precision medicine in oncology is an evolving therapeutic approach that leverages genetic, clinical, and biomarker data to tailor treatments to individual patients. This review explores the three core pillars of modern precision oncology: targeted therapy, immunotherapy, and the integration of artificial intelligence (AI) into clinical practice. Targeted therapies, including monoclonal antibodies and antibody-drug conjugates, selectively inhibit molecular pathways involved in tumor growth. While conventional chemotherapy remains the backbone of treatment and has improved remission rates, its cytotoxic nature limits broader applicability and increases the risk of comorbidities. Immunotherapies, particularly immune checkpoint inhibitors and chimeric antigen receptor T-cell therapies, have transformed …

Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder: An Enigma-Pgc Ptsd Study, Jacklynn M. Fitzgerald

Psychology Faculty Research and Publications

Using functional magnetic resonance imaging (fMRI), symptoms of posttraumatic stress disorder (PTSD) have been associated with aberrations in brain networks in the absence of a given cognitive demand or task, called resting-state networks. Prior work has focused on disruption in the static functional connectivity (FC) among specific regions constrained by a priori hypotheses. However, dynamic FC, an approach that examines brain network characteristics over time, may provide a more sensitive measure to understand the network properties underlying dysfunction in PTSD. Further, using a data-driven analytic approach may reveal the contribution of other larger network disturbances beyond those revealed by hypothesis-driven …

A Comprehensive Review On Machine Learning-Based Job Recommendation Systems, Shaymaa Al-Juboori, Su-Cheng Haw, Rui Ern Yap

School of Engineering, Computing and Mathematics

A dynamic, constantly shifting labor market creates enormous job postings, overwhelming candidates and making it difficult for businesses to find quality candidates. It is also hard for job seekers to find suitable jobs. Addressing these issues, machine learning-driven job recommender systems have recently become an essential tool using predictivemodels to improve the match between jobs and candidates. A hybrid design that combine scollaborative filtering with content-based filtering andadds contextual information like geographic location,industry trends, and user behavioural data can enhance the accuracy and relevance of recommendations. This paper reviews and critically analyzes contemporary jobre commender system techniques. The focus is …

Unmasking The Heart Of Osimertinib: A Closer Look At Drug-Induced Cardiotoxicity, Muhammad Sabri, Aheed Javaid, Hussam Al Hennawi, Hamza Muhammadzai, Vamshi Mallavarapu

Abington Jefferson Health Papers

BACKGROUND: Osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, is an effective therapy for epidermal growth factor receptor-mutated non-small cell lung cancer, but it has been associated with a higher incidence of cardiotoxicity.

CASE SUMMARY: A 91-year-old woman on osimertinib 80 mg daily presented with acute dyspnea and was found to have a newly reduced left ventricular ejection fraction of 30%. Coronary angiography excluded obstructive coronary disease. Osimertinib was discontinued, and guideline-directed medical therapy (GDMT) was initiated, resulting in left ventricular ejection fraction recovery to 60%. The patient was successfully rechallenged with osimertinib while continuing GDMT, without recurrence …

The Complete Poetry And Selected Prose Of John Donne & The Complete Poetry Of William Blake, John Donne, William Blake

Hannah Arendt Marginalia - All

New York, Modern Library [1946]

Call #: PR2245.A5 H3 1946

Contains gift inscription by “Arthur Lapa?”

PDF Information: 13 pages – 948 KB

Problems Of Men, John Dewey

Hannah Arendt Marginalia - All

New York, Philosophical library, 1946

Call #: B945.D43 P7

Contains underlining and endpaper notes.

PDF Information: 26 pages – 10.9mb

Using A Layered Ensemble Of Physics-Guided Graph Attention Networks To Predict Covid-19 Trends, Connie Sun, Vijayalakshmi Kumarasamy, Yu Liang, Dalei Wu, Yingfeng Wang

UTC Spring Research and Arts Conference

The COVID-19 pandemic has rapidly disseminated worldwide, profoundly impacting numerous nations. Accurately forecasting the trajectory of COVID-19 across various scales is crucial for informing public health decisions. However, existing forecasting models primarily operate at the state or country level. Conventional mathematical models face limitations due to oversimplified assumptions, while machine learning algorithms struggle to extrapolate novel trends. This underscores the necessity for hybrid machine learning models that amalgamate domain expertise to enable precise long-term predictions. In response, we propose a sophisticated three-layered ensemble, tailored to geographical insights and fostering extensive peer learning. Our framework aims to forecast COVID-19 trends at …

Pretty Dangerous: The Romanticization Of Grooming In Pretty Little Liars, Katherine G. Johnson, Emma Grace Gilland

UTC Spring Research and Arts Conference

Sexual grooming is the deliberate manipulation of a minor by an adult to reduce their sensitivity to sexual contact, with the specific aim of perpetrating child or adolescent sexual abuse (Winters, 2022). Prevalence rates for sexual grooming vary; however, a recent study by Winters and Jeglic (2022) found that approximately 24% of their sample of undergraduate student sample reported experiencing sexual grooming as a minor. These predatory behaviors were prominently featured between lead adolescent and adult characters throughout the popular television show, Pretty Little Liars. This raises concerns about how such behaviors might be perceived when portrayed in popular media …

A Comparative Study On Viral Fitness Among Influenza Virus Strains Across Different Periods And Locations, J M Imtinan Uddin, Hong Qin

UTC Spring Research and Arts Conference

Influenza viruses, in 1918, 1957, 1968, and 2009 causing pandemics of contagious respiratory illnesses, have taken away millions of lives worldwide [1][2]. Still, many influenza virus strains are circulating worldwide, infecting people in the USA and other countries [3]. Furthermore, influenza viruses are constantly changing, called "antigenic drift"[4]. These circulating influenza virus strains in humans present a potential threat to another pandemic, like the SARS-CoV-2 pandemic. For this reason, We must revise our risk assessment and preparedness plans to mitigate the risk of another pandemic and should continue to put surveillance on influenza virus strains on different hosts [5]. For …

A Combination Of Modified Stacking Method With Voting Ensemble Technique For Binary Classification, J M Imtinan Uddin, Hong Qin

UTC Spring Research and Arts Conference

Binary classification is a frequently encountered machine learning problems. Many machine learning algorithms are used to solve binary classification problems. However, all machine learning algorithms are not suited or efficient for solving binary classification problems.

In this paper, authors has proposed a approach. The proposed approach is a machine learning algorithm, to solve binary classification problems. Authors has combined modified stacking and voting ensemble machine learning techniques for binary classification problems. Before combining the ensemble techniques, authors has modified the stacking ensemble technique for making the proposed method more robust.

This proposed method was applied on two different binary class …

Achieving Outcomes In Analytical Chemistry While Focusing On Active Learning And Self-Care, Gretchen E. Potts Ph.D.

UTC Spring Research and Arts Conference

Pedagogy can support self-care and student outcomes in the chemistry classroom. In fact, intentional course design to support the whole student may improve overall student outcomes. A quantitative analysis lecture course that was designed synchronously online during COVID was transitioned to a face-to-face environment in an active learning classroom. Discussion boards were converted to daily group work that highlighted collaboration. Small adjustments were implemented to the course and syllabus design to help students manage stress and to encourage self-care. Frequent anonymous check-ins were used to monitor student learning progression. Additional anonymous prompts encouraged students to share study tips, how to …

Artificial Wetlands Provide Hope For Municipal Sewage Effluent Treatment And Biodiversity Declines, William T. Bryant

UTC Spring Research and Arts Conference

Wetlands provide habitat for a multitude of species worldwide and exist on almost every continent. They act as water filtration systems, cycle organic and inorganic nutrients, prevent flooding and mitigate storm damage. As the human population continues to expand and cities continue expanding, more infrastructure is needed for water treatment and providing green spaces for citizens to enjoy. This literature review analyzes the current data on the effectiveness of constructed wetlands in the treatment of sewage effluent and how they impact the biodiversity of the local ecosystem. The databases Web of Science, ProQuest and Agriculture, Ecosystems and Environment were utilized. …

The Delegation Dilemma: Assessing How The Overturn Of Chevron Paves The Way For The Revitalization Of The Nondelegation Doctrine, Elizabeth Paige Sonnenschein

Helms School of Government Undergraduate Law Review

The nondelegation doctrine is derived from Article I of the United States Constitution, and it prohibits Congress from delegating its enumerated legislative powers to other branches or agencies of the government. However, the nondelegation doctrine has been limited over the last century, and it has not been enforced to the fullest extent in the Supreme Court since the 1935 ruling in A.L.A Schechter Poultry Corp. v. United States. As a result, Congress has been allowed the discretion to delegate quasilegislative powers to administrative agencies and the executive branch under the premise of the intelligible principle and various levels of …

Equality Or Equity?: Weighing Prima Facie Cases In Reverse Discrimination Claims, Emerson Lawrence Allen

Helms School of Government Undergraduate Law Review

Title VII of the Civil Rights Act of 1964 protects against employment discrimination. In suits based on this protection, the plaintiff must typically be able to satisfy the four-prong McDonnell Douglas test in order to make a prima facie case and avoid summary judgment in favor of the defendant. Although Title VII fully protects all plaintiffs, the first prong of this test historically requires the plaintiff to show membership in a minority group. The United States Courts of Appeals are, however, split on what standard to require in reverse discrimination cases. There are currently four approaches: one requiring the plaintiff …

Forced Labor In Soviet Russia, David J. Dallin, Boris I. Nikolaevsky

Hannah Arendt Marginalia - All

New Haven, Yale University Press, 1947

Call #: HV8931.R8 D3

contains underlining, marginal lining and endpaper notes (front of book)

PDF information: 35 pages – 3.1 MB

On World-Government, Or De Monarchia, Dante Alighieri

Hannah Arendt Marginalia - All

New York : The Liberal Arts Press, c1957

Call #: PQ 4315.62 .S3 1957

Contains marginalia & underlining

PDF Information: 31 pages – 12 MB