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Protecting Sleep To Reduce Delirium In Patients 65 Years And Older In The Icu, Jessica L. Thomas

Doctor of Nursing Practice Final Project Abstract

Protecting Sleep to Reduce Delirium in Patients 65 Years and Older in the ICU

PURPOSE

This quality improvement (QI) project aimed to reduce the incidence of delirium by 30% through a nurse-initiated, non-pharmacological sleep improvement protocol in the ICU.

BACKGROUND

This project was implemented in a large healthcare organization in Houston, Texas, in a 16-bed Intensive Care Unit.

METHODOLOGY

A pre- and post-intervention study was conducted in the ICU over a period using Plan-Do-Study-Act (PDSA) cycles. Baseline delirium (CAM-ICU) and sleep quality (RCSQ) assessments were obtained during Phase 1. Environmental adaptations, such as low lighting, noise reduction, staff education, and …

Digital-Based Nutrition Interventions Employing The Dietary Approaches To Stop Hypertension (Dash) Diet: A Systematic Scoping Review, Elizabeth Dodge, Patricia J. Kelly, Basil H. Aboul-Enein

College of Nursing Faculty Papers & Presentations

Background: The Dietary Approaches to Stop Hypertension (DASH) diet is an internationally recognized anti-hypertensive dietary model. This systematic scoping review examines the effectiveness of digital-based interventions utilizing the DASH dietary pattern. Methods: A search was conducted using 14 databases to include relevant studies from 1997 to January 2025 using PRISMA guidelines for scoping reviews. Results: The review included 24 studies with almost 7000 participants, including randomized controlled trials and cohort studies conducted in several countries. Interventions using the DASH dietary pattern positively affected blood pressure (BP), nutrition behavior, and weight. Some studies also reported secondary outcomes such as reduced healthcare …

Kind Kids, Healthy Teens: Child Prosociality And Fruit And Vegetable Intake, Farah Qureshi, Krista P. Woodward, Laura D. Kubzansky, Julia K. Boehm

Psychology Faculty Articles and Research

Introduction

Methods

Intouch Week Of August 11, 2025, New York Medical College

InTouch

• New Chief Development Officer Joins NYMC
• GSBMS Welcomes a New Cohort of Students
• 20 Years of Revolutionizing Emergency Preparedness
• Study Calls for Nuanced Approach to Stroke Care in Sexual and Gender Diverse Patients
• NYMC and TU Host “Ninety Minutes: The Medical Magazine of the Web”
• Back-to-School Savings
• TCDM Announces its First Alumni Association Executive Board

Hippocampal Avoidance During Prophylactic Cranial Irradiation For Patients With Small Cell Lung Cancer: Randomized Phase Ii/Iii Trial Nrg-Cc003, Vinai Gondi, Stephanie L Pugh, Minesh P Mehta, Jeffrey S Wefel, Wolfgang A Tomé, Alexander Y Sun, John Grecula, Kristin J Redmond, Shannon Fogh, Laurie Gaspar, Andre Konski, Joseph Bovi, Clifford G Robinson, Benjamin Corn, Gregory M Videtic, Benjamin H Lok, Harold A Yoon, John H Heinzerling, Albert S Denittis, Ronald C Mcgarry, Kiran Devisetty, Vijayananda Kundapur, Abraham J Wu, Edward C Mccarron, Isabelle Thibault, Edmund L Simon, Andrew M Baschnagel, Samir Narayan, Jondavid Pollock, Rebecca Paulus, Lisa A Kachnic

Faculty, Staff and Student Publications

Purpose: Hippocampal avoidance (HA) during therapeutic whole-brain radiotherapy reduces the risk of neurocognitive function (NCF) toxicity in patients with brain metastasis. This trial hypothesized that HA during prophylactic cranial irradiation (PCI) in patients with small cell lung cancer (SCLC) leads to noninferior intracranial relapse (ICR) and reduction in NCF toxicity.

Methods: This randomized phase II/III trial enrolled patients with SCLC, no brain metastases, and response to chemotherapy. The primary end points were 12-month ICR (noninferiority design, randomized phase II) and 6-month Hopkins Verbal Learning Test-Revised (HVLT-R) Delayed Recall (DR) failure (phase III). Secondary end points were failure in any NCF …

Keap1 And Stk11/Lkb1 Alterations Enhance Vulnerability To Atr Inhibition In Kras Mutant Non-Small Cell Lung Cancer, Ana Galan-Cobo, Natalie I Vokes, Yu Qian, David Molkentine, Kavya Ramkumar, Alvaro G Paula, Marlese Pisegna, Daniel J Mcgrail, Alissa Poteete, Sungnam Cho, Minh Truong Do, Amirali Karimi, Yifan Kong, Anisha Solanki, Ankur Karmokar, Nicolas Floc'h, Adina Hughes, Rebecca Sargeant, Lucy Young, Li Shen, Gozde Kar, Caezaan Keshvani, Claudio Arrechedera, Sharia Hernandez, Katharina Schlacher, Jing Wang, Sonia Iyer, James Conway, Mohamed Reda Keddar, Marta Milo, Ilario De Toma, Susan E Critchlow, J Carl Barrett, Jan Cosaert, Alan Lau, Viia Valge-Archer, Lauren A Byers, Simon T Barry, John V Heymach

Faculty, Staff and Student Publications

KRAS mutations frequently co-occur with alterations in STK11/LKB1 and/or KEAP1, defining an aggressive subset of lung cancers resistant to immuno- and chemotherapy. While LKB1 loss is associated with vulnerability to DNA damage response-based therapies, the impact of KEAP1 alterations remains unknown. We demonstrate that KEAP1-NRF2 pathway drives a compensatory modulation of ATR-CHK1 signaling, enhancing vulnerability to ATR inhibitors (ATRi), particularly in the setting of increased replication stress associated with LKB1 loss. ATRi shows enhanced anti-tumor activity in LKB1 and/or KEAP1-deficient non-small cell lung cancer (NSCLC) models and synergizes with gemcitabine. ATRi also enhances antitumor immunity and mitigates the immunosuppressed phenotype …

Health Outcomes Beyond Age 50 Years In Survivors Of Childhood Cancer: A Report From The Childhood Cancer Survivor Study, Rusha Bhandari, Yan Chen, Eric J Chow, Rebecca M Howell, Lisa B Kenney, Kevin R Krull, Wendy Leisenring, Paul C Nathan, Joseph P Neglia, Kirsten K Ness, Kevin C Oeffinger, Claire Snyder, Lucie M Turcotte, F Lennie Wong, Yutaka Yasui, Gregory T Armstrong, Saro H Armenian

Faculty, Staff and Student Publications

Purpose: There are limited data on the risk for mortality and health outcomes among the increasing population of older (age >50 years) survivors of childhood cancer during this later stage in life when there is an expected increase in aging-related morbidities.

Methods: We assessed cause-specific mortality, incident new cancers, chronic health conditions (CHCs), frailty, and health status among survivors from the Childhood Cancer Survivor Study, conditional on surviving to 50 years. We calculated conditional survival rates, standardized mortality ratios (SMRs), and, for incident new cancers, cumulative burden, standardized incidence ratios (SIRs), and relative rates (RRs), compared with the general US …

Agricultural Biotechnology In The Courts: Judicial Opinions And Commentary, Drew L. Kershen

Faculty Articles

Seven jurisdictions from around the world have issued judicial opinions that address fundamental issues about the governance and regulatory systems of agricultural biotechnology. This article summarizes these legal proceedings and describes their impact upon agricultural biotechnology. The article then provides a commentary and critique of the legal proceedings and resulting judicial opinions.

Spontaneous Closure Of A Patent Processus Vaginalis: A Case Report, Haley Kittle, Amber Lee Geng, Loren Berman, Erin Teeple

Department of Surgery Faculty Papers

Introduction: Patent process vaginalis and inguinal hernia are prolific in infants, and their repair is a common pediatric surgical procedure. However, there is a paucity of direct evidence detailing the spontaneous closure of patent processus vaginalis.

Case presentation: A 4-month-old boy born prematurely at 34-weeks with low gestational birth weight, underwent laparoscopic gastrostomy tube placement for oropharyngeal dysphagia and was incidentally found to have bilateral patent processes vaginalis. Due to his lack of symptoms, he was managed under the watchful waiting approach. His parents were educated about signs and symptoms of inguinal hernia and were instructed to contact the team …

Post-Pandemic Restaurant Patronage: The Importance Of Neuroticism In Shaping In Person Dining Intentions., Matthew Gorton, Min Yan, Honglyu Lin, Dora Gaćeša Brlić, John White, Ružica Brečić, Ana Tkalac Verčič

Plymouth Business School

Purpose Even after the lifting of all government restrictions, introduced to combat the spread of Covid-19, many consumers remain fearful of in-person dining. This paper seeks to understand this reticence, and explain post-pandemic restaurant dining intentions. Design/methodology/approach The paper introduces and tests a conceptual framework for understanding in-person dining intentions in the post-Covid-19 era, utilizing structural equation modelling. To empirically validate the model, survey data collection (n = 436) occurred in China after the government lifted its “Zero-Covid” policy. Findings Neuroticism, as a personality trait, negatively affects restaurant trust and increases fear of Covid-19 (threat appraisal), which in turn reduces …

Effect Of Potassium Fertilizer On The Nutrition And Physical Quality Of Job’S Tears (Coix Lacryma-Jobi L.) Seeds, Qinthara Nail Haysa, Yuyun Yuwariah, Fiky Yulianto Wicaksono

Jurnal Kultivasi

Job's tears is a cereal crop that has beneficial nutrients. Potassium is known to affect the growth and yield of cereal crops, but there has been limited study on whether potassium affects the nutrition and physical quality of Job’s tears seeds. This study aimed to analyze the effect of K fertilizer on the nutritional content and physical quality of Job's tears seeds. This research was conducted from January to May 2024 at Ciparanje Experimental Field, Faculty of Agriculture, Universitas Padjadjaran, Sumedang, Indonesia. This experiment used the Randomized Block Design (RBD) method with six treatments and four replications. Various doses of …

Core Outcome Set And Measures Of Chest Health In Children And Young People With Cerebral Palsy In The Community Setting: The Chesti Study Protocol, Chesti-Study Steering Group, Rachel Knight Lozano, Christopher Morris, Harriet Shannon, Kayleigh Bell, Hugh Malyon, Julia Melluish, Jos Latour, Morag Andrews, Sarah Crombie, Noula Gibson, Samantha Grace, Sian Goddard, Nicola Harman, Sarah Mc Goldrick Kolawole, Laura Lowndes, Paul Mcnamara, Madeline Pilbury, Rachel Rapson, Nicola Scivier, Diane Sellers, Caroline Weighton, Mark Williams, Luana Winston

School of Health Professions

Introduction Poor chest health is the leading cause of early mortality in children with cerebral palsy (CP). It is also the most common reason to seek healthcare, accruing significant costs and reducing quality-of-life for children and families. Clinical trials examining chest health interventions in CP are characterised by inconsistent outcome measures, limiting the capacity for evidence synthesis to inform clinical application. The study aims to develop a core outcome set (COS) and related measurement instruments to assess, monitor and evaluate chest health in children with CP, both in research and routine clinical practice. The COS will reflect the views of …

High Temperature In Potato: Plant Responses And Adaptive Cultivation Strategies To Increase Production, Siska Rahmayani Gultom, Jajang Sauman Hamdani, Kusumiyati

Jurnal Kultivasi

Climate change, with global temperatures rising by 1.09°C from 1850–1900 to 2011–2020, threatens potato production, a critical staple crop, by exceeding the optimal temperature range of 15–20°C. This review synthesizes over 45 peer-reviewed studies published between 2015 and 2025 from Google Scholar and ScienceDirect to evaluate the physiological, morphological, and tuber quality responses of potatoes to high temperatures and to identify adaptive cultivation strategies for sustainable production. High temperatures reduce photosynthetic efficiency through chlorophyll degradation and stomatal closure, increase respiration, and divert photosynthates to vegetative growth, leading to 18–32% yield losses globally by the 2050s. Heat-tolerant varieties, such as Atlantic …

Deriving Profiles Of Psychosocial Supports And Challenges, And Predicting Longitudinal Trajectories Of Hba1c To Promote Flourishing In Adolescents With Type 1 Diabetes (T1d), Kishan Desai

Electronic Theses and Dissertations Archive

Managing type 1 diabetes (T1D) is emotionally demanding, especially for adolescents navigating intersecting developmental, biological, and psychosocial transitions. Routine psychosocial screening may help address youths’ needs. One hundred eighty adolescents with T1D ages 12-18 (M=14.71, SD=1.69 years) were recruited from a pediatric diabetes clinic. Confirmatory Factor Analyses confirmed a six-factor structure, and Latent Variable Mixture Modeling identified three profiles of psychosocial supports and challenges: (1) Average Supports, Low Challenges (n = 105, 58%), (2) Low Supports, High Challenges (n = 37, 20%), and (3) Average Supports, High Family Conflict (n = 38, 22%). Illness duration and race-income interactions predicted profile …

Statistical Literacy As Health Literacy: The Role Of Emotions In Health Decision-Making, Kendra Murphy

Electronic Theses and Dissertations Archive

Lifestyle-related health problems remain a leading cause of chronic illness in the United States, creating a need for more effective communication of health information. However, the mechanisms that influence how individuals understand and use health information are not yet fully understood. This exploratory study investigates the intersections of statistical health literacy, emotions, and health decision-making from an interdisciplinary perspective. Guided by prior literature suggesting potential relationships among these factors, the study hypothesized that statistical literacy and emotional responses would modify responses to the form of health information presentation, affect the believability and motivational impact of the information, and influence health …

Disunion And Convict Labor Along The Gulf Coast Pine Belt, 1870-1930, Brianna Harrison

Electronic Theses and Dissertations Archive

This project examines lumber and naval stores workers from the late nineteenth and early twentieth centuries along the Gulf Coast of Louisiana, Mississippi, Alabama, and Florida. After the Civil War, lumbermen who had exhausted the timber supply in the North and Midwest looked to the South’s pine forests as the national demand for lumber and lumber products increased. The creation of the lumber and naval stores industries along the Gulf Coast pine belt, however, coincided with labor abuses, including the convict lease system and debt peonage. Moreover, company owners and management structured the industries in a way that perpetuated the …

All In God's Plan?: Examining Positive And Negative Religious Coping As Moderators Of Posttraumatic Stress And Alcohol Use Following Intimate Partner Violence Exposure, Mya Elizabeth Bowen

Electronic Theses and Dissertations Archive

Intimate partner violence (IPV) is defined as physical violence, sexual violence, stalking, or psychological aggression by a current or former intimate partner or spouse (The Centers for Disease Control and Prevention, 2020). Recognized as a pervasive public health concern, approximately 41% of women report experiences of sexual violence, physical violence, and/or stalking, and over 61 million women report experiencing psychological aggression, all at the hands of an intimate partner (Leemis et al., 2022). The pervasive nature of IPV is particularly concerning as experiences of violence can result in significant negative physical and psychological health concerns, including the development of PTSD …

Optimising The Care Of The Trapped Patient Following A Motor Vehicle Collision: A Uk-Based Delphi Consensus Study, Tim Nutbeam, Rob Fenwick, Ian Marritt, Brian Lee, Luke Staveley-Wadham, Nigel Lang, Louise Johnson, Nicolas Mattock, Jane Ogilvie, Emily Foote, Francis Screech, Lara Lebeau-Humarau, Caroline Leech

Peninsula Medical School

Background Motor vehicle collisions (MVCs) are a leading cause of injury and death worldwide. Up to 40% ofcasualties may become trapped and entrapment is associated with delayed care and worse outcomes. There is littlenational or international consensus guiding the care of physically trapped patients who cannot self-extricate. Thisstudy aimed to develop multidisciplinary consensus-based principles to optimise clinical and operational care fortrapped patients following MVC.Methods A three-round Delphi study was conducted from January to March 2025, following the CREDES framework.A multi-professional steering group developed preliminary statements informed by literature review and expertconsultation. Subject matter experts (SMEs) with operational experience in extrication, …

European And African Ancestry-Specific Plasma Protein-Qtl And Metabolite-Qtl Analyses Identify Ancestry-Specific T2d Effector Proteins And Metabolites, Chengran Yang, Priyanka Gorijala, Jigyasha Timsina, Lihua Wang, Menghan Liu, Ciyang Wang, William Brock, Yueyao Wang, Fumihiko Urano, Yun Ju Sung, Carlos Cruchaga

2020-Current year OA Pubs

In this study, we generated and integrated plasma proteomics and metabolomics with the genotype datasets of over 2300 European (EUR) and 400 African (AFR) ancestries to identify ancestry-specific multi-omics quantitative trait loci (QTLs). In total, we mapped 954 AFR pQTLs, 2848 EUR pQTLs, 65 AFR mQTLs, and 490 EUR mQTLs. We further applied these QTLs to ancestry-stratified type-2 diabetes (T2D) risk to pinpoint key proteins and metabolites underlying the disease-associated genetic loci. Using INTACT that combined trait-imputation and colocalization results, we nominated 270 proteins and 72 metabolites from the EUR set; seven proteins and one metabolite from the AFR set …

Degradation Of Anthropogenic Debris In Stormwater Infrastructure Of The Lake Ontario Watershed, Evan Batte

Theses

The accumulation of anthropogenic debris (AD) in the Great Lakes is a growing issue with largely unknown consequences for ecological and human health. To better constrain estimates of debris loading into Lake Ontario and elucidate the fate of AD accumulating upstream, an incubation experiment of the most commonly identified littered products was conducted in different stormwater infrastructure within the Lake Ontario Watershed. Chip bags, cigarette filters, and shopping bags were placed into storm drains, stormwater retention ponds, and along riparian zones of tributaries in December of 2022 and July of 2023 to test the spatial (type of stormwater infrastructure [SWI]) …

Coolness, Leisure, And Power : The Development Of Mokanshan Summer Resort In Modern China, 1890–1937, Xuyan Pan

Lingnan Theses (MPhil & PhD)

The concept of "coolness" (清涼) embodied fundamentally different bodily and cultural experiences in Chinese and Western traditions. With the introduction of Western-style summer resorts by foreign missionaries in the 1890s, these divergent understandings converged and clashed in new spatial forms. This study examines Mokanshan (莫干山), located in Zhejiang province and recognized as one of the Republican era’s “Four Great Summer Retreats” (民國四大避暑地), as a paradigmatic case of transnational leisure. Initially developed by missionaries as a health-oriented retreat, a transnationally managed enclave, and a nostalgic “overseas home” for expatriates, Mokanshan reflected a hybrid model of modern leisure shaped by foreign institutions. …

Approaches For Identifying Lncrna-Associated Proteins For Therapeutic Targets And Cancer Biomarker Discovery, Mohammad Shabir Hussain, Puneet Vij, Sudhir Kotnala, Shadab Ahmad, Subhash Chauhan, Manish Kumar Tripathi

School of Medicine Publications

Long non-coding RNAs (lncRNAs) are increasingly recognized as key regulators of gene expression and cellular signaling in cancer. Their functions are primarily mediated through interactions with specific protein partners that modulate chromatin structure, epigenetic remodeling, transcription, and signal transduction. In this review, we explore reports and strategies for the proteomic characterization of lncRNA-associated proteins, particularly emphasizing high-throughput liquid chromatography–mass spectrometry (LC-MS)-based techniques. Affinity-based methods such as RNA pull-down, ChIRP MS, RAP-MS, BioID-MS, and SILAC-MS enable sensitive and specific mapping of lncRNA and protein complexes. These approaches reveal cancer-specific proteomic signatures, post-translational modifications, and mechanistic insights into tumor biology. The use …

International Collaboration To Explore Elements For An Effective Residential Childcare Workforce, Justyna Siemionow, Patrick M. Tyler, W. Alex Mason, Deogratias Musoke, Maia Ordonez, Jaime A. Gomez-Blaya, Joseph G. Grzywacz

Faculty Research, Scholarly, and Creative Activity

Residential childcare workers provide critical support to vulnerable children around the world. Building and maintaining a qualified residential childcare workforce is challenged by myriad forces, the foremost of which is recruiting and retaining staff for valuable work often misaligned with available compensation; making individual qualifications at hiring; ongoing training; supervision; and data support systems to monitor performance critical for quality care. This study explored the similarities and differences among these essential elements of staffing across distinct programs: Youth Education Centers (YEC) in Poland, CiudadEscuela Muchachos (CEMU) in Spain, and the Boys Town Family Home Program (BTFHP) in the United States. …

Botulinum Toxin For The Treatment Of Tremors, Steven Bellows, Joseph Jankovic

Faculty, Staff and Students Publications

Tremor, an oscillatory movement disorder, is commonly encountered in clinical practice in the setting of a variety of etiologies, such as essential tremor and Parkinson's disease. Despite its high prevalence, treatment options are somewhat limited. Oral medications are often ineffective or limited by side effects, and other treatments, such as deep brain stimulation, are more invasive and costly. Botulinum toxin (BoNT) injections are a well-established therapy in the treatment of dystonia, but its use in the treatment of tremors has not been fully explored. In this review, we discuss the available randomized controlled trials and open-label evidence for the use …

Enhancements And Improvements Of The Radiation Probe - Compact Radiation Probe (Crp), Yihsuan Chou, Loren Chang, Yichung Chiu, Tzuwei Hung, Sinyu Tsui

Small Satellite Conference

As space missions venture beyond Earth's magnetic field, spacecraft face elevated risks from solar energetic particles (SEPs) and galactic cosmic rays (GCRs). Taiwan's first lunar payload—the Deep Space Radiation Probe (DSRP)—was developed to measure radiation dose, dose rate, and SEU rates during Earth–Moon transit. However, flight data revealed limitations in SEU detection and system operation. To address these issues and support CubeSat-class missions, the Compact Radiation Probe (CRP) was developed for the upcoming COSPAR-1 mission.

Occupational Therapy For Individuals With Low Vision Affecting Their Mental Health, De'aundria M. Gipson, Jaimee Fielder, Becky King

Summer 2025 OTD Capstone Symposium

Low vision is a prevalent public health issue among older adults, often leading to functional limitations, reduced participation in activities of daily living (ADLs), and increased risk of mental health challenges such as depression, anxiety, and social isolation. This capstone project explored the relationship between low vision and mental health by developing and evaluating a program to address both functional and psychosocial needs. Guided by the Person-Environment-Occupation (PEO) model, the program was implemented at Envision Dallas and included a needs assessment, tailored strategies, and group activities targeting emotional well-being, independence, and social participation. Data from surveys, interviews, and observation indicated …

Digitalization In Logistics And Supply Chain Management For Agro-Processing Smes In Kahama And Msalala – Tanzania, Mohammed Semkunde

Business Management Review

This study explored the growing landscape of Logistics and Supply Chain Managemnent (LSCM) focusing on Small and Medium Enterprises (SMEs) in Tanzania. The purpose was to examine on how digitalization is adopted and utilized in the agro-processing sector by SMEe in Kahama and Msalala districts to enhance their LSCM practices. Through the lense of Technological Acceptance Model, Resource Based View and Institutional Theory framework, the study employed a qualitative case study design in which pattern matching technique was used for data analysis. The main findings reveal that there are varying levels of digital adoption across SMEs, improved efficiency for digitally …

What Comes Before?_Student Learning Before Tertiary Education, Strutts Psyridis

Staff Scholarship - Australia & Dubai

This weblog article examines how prior schooling shapes student readiness for creative arts degrees, arguing that recognising prior learning enables better scaffolding, reduces misdiagnosis of skills gaps, and improves inclusive, constructivist teaching.

Editorial: Health Misinformation: Examining Its Presence And Impact Across Communication Contexts, Christopher Mckinley

College of Communication and Media Scholarship and Creative Works

No abstract provided.

Ubi Jus Ibi Remedium: Self-Determination, Devolution, And The Scottish Right To Independence, Soares, Kyra

Santa Clara Journal of International Law

No abstract provided.