Digital Commons Network^™

An Analysis Of The Health Disparities For Traumatic Brain Injury Care In Urban Vs. Rural Populations, Jeremy R. Russell

Doctoral Dissertations and Projects

The purpose of this quantitative research study was to examine how disparities between urban and rural environments impacted the amount, onset, and duration of care received by patients with mild traumatic brain injury, as well as differences in demographic characteristics such as age and gender. Mild TBIs, often referred to as concussions, involve a temporary disruption in brain function resulting from external force, leading to symptoms like confusion, dizziness, or memory issues. Guided by critical theory, this study explored how systemic structures contributed to unequal healthcare experiences. Since TBIs remained a leading cause of disability and death with potential long-term …

A Qualitative Phenomenological Study Of The Role Of Spiritual Mindfulness Practices In Coping With Divorce Loss In Christian Women, Gale Louise Nicolai

Doctoral Dissertations and Projects

This phenomenological study aims to understand the role of spiritual mindfulness practices in counseling individuals who have experienced divorce. The theory guiding this study is the biopsychosocial-spiritual model, which recognizes the interconnectivity and mutual influence of biological, psychological, social, and spiritual factors. This data will be descriptive, using open-ended interview questions. Data analysis will be thematic. The study participants are women who self-identify as Christian at 1-10 years post-divorce. The independent variable is spiritual mindfulness practices. The dependent variables are women who self-identify as Christian at 1-10 years post-divorce.

The Effects Of The Menstrual Cycle On Movement Velocity In Female Athletes, Casey M. Krolikowski

Doctoral Dissertations and Projects

This study examined the psychological and physiological impacts of menstrual cycle phase and hormonal contraceptive (HC) use on barbell back squat and bench press velocity, handgrip strength, and countermovement jump height. The aim was to determine whether HC use and premenstrual syndrome (PMS) symptoms affected performance during menstruation, the late follicular phase (LFP), or the mid-luteal phase (MLP). Fourteen college-aged female athletes (N = 14) were divided into HC users (n = 7), and naturally menstruating, eumenorrheic individuals (n = 7). Movement velocity data was assessed using RepOne linear position transducers, jump height with the Just Jump mat, and grip …

Exploring The Effects Of The Covid-19 Pandemic On The Biblical Organizational Culture Of A K-12 School In Kansas, Michael Jacob Wiebe

Doctoral Dissertations and Projects

The purpose of this qualitative research design was to understand the lived experiences of K-12 Christian school teachers regarding the perceived impact of the COVID-19 pandemic on the biblical organizational culture of a school in Wichita, Kansas. A qualitative interview methodology was utilized for teachers to answer questions pertaining to their own experiences in changes within the school, the school’s environment, and the school’s level of involvement in a biblical culture during and post the COVID-19 pandemic. The data were analyzed to understand the effects and the changes the COVID-19 pandemic has had on K-12 Christian school biblical organizational culture, …

Centralizing Discipleship Through Small Groups, Roger O. Nelmes

Doctoral Dissertations and Projects

Centralizing Discipleship through Small Groups explores how intentional leadership development and relational disciple-making practices can reframe a megachurch’s approach to spiritual formation. Conducted at Hope City, a dynamic, urban, multisite nondenominational congregation, this mixed-methods action research integrates qualitative interviews, quantitative Likert scale surveys, and a focus group to evaluate the effectiveness of a holistic discipleship framework. Key interventions included a Group Leader Intensive Training (LIT), the implementation of Rooted small groups, and the launch of Intentional Relational Discipleship (IRD) groups, all designed to shift the church’s culture from attractional programming to a missional, relational ethos. Data revealed that small groups, …

Evaluating Mental Health Providers’ Knowledge And Attitudes Towards Stigma Among Teenagers Aged 13 To 19 Years With Mental Illness, Fredrica Murray-Johnson

Doctoral Dissertations and Projects

Limited knowledge and poor attitudes among mental health providers contribute to stigma towards individuals with mental illness, adversely affecting treatment experience and outcomes. This study evaluated the effectiveness of an educational intervention in improving mental health providers’ knowledge and attitudes toward stigma-based practices. The clinical question stated: Among mental health providers, does an educational intervention, compared to standard practice, improve knowledge and attitudes of stigma and promote evidence-based care delivery to teenagers aged 13 to 19 with mental illness within six weeks? The Iowa Model of Evidence-Based Practice (EBP) was used as a framework for implementing this study. The quasi-experimental …

The Role Of Standard Business And Biblical Principles In The Strategic Human Resource Management Practices Of Contemporary Protestant Churches, Brandon Marshall Mccutchen

Doctoral Dissertations and Projects

Strategic Human Resource Management (HRM) practices have consistently evolved in the for-profit business sector to support business profitability. Nonprofit organizations have also adopted strategic HRM practices. Despite their status as tax-exempt nonprofit organizations, contemporary Protestant churches have not been included in the current literature discussing the use of strategic HRM practices in nonprofit organizations. Adoption of an HRM strategy varies across the spectrum of nondenominational Christian churches, and churches that are affiliated with a denomination. This qualitative study assesses the leadership perspective of five local churches to determine how standard business practices and biblical principles combine to create a formal …

The Christian Church’S Inclusion Of Children With Autism Who Experience Parental Incarceration: A Phenomenological Examination Of Christian Ministry Leaders’ Experiences, Julia Frances Vasquez

Doctoral Dissertations and Projects

The United States has the highest incarceration rate worldwide. Parental incarceration increases children’s susceptibility to adverse childhood experiences and often results in the transmission of criminal behavior. Research on children of incarcerated parents and separate findings on the experiences of children with autism reveal that these children endure bitter societal stigma, even within the church. Stigma toward disability erects barriers to much-needed spiritual support. There is a gap in the literature concerning Christian outreach and spiritual community support for children with autism who experience parental incarceration. Understanding effective ministry support for these dually marginalized children and the barriers preventing access …

Divine Grace In Human Flourishing Amid Suffering, Sutjipto Utomo

Doctoral Dissertations and Projects

Human flourishing is as potent as it is intricate. There is a need in the Christian context for a model of human flourishing among other available models. This current qualitative study seeks to gather insights into human flourishing amid suffering among Methodist clergy in Indonesia. The phenomenological approach delved into the essence of encountering the grace of the Lord and flourishing amid the adversities in their ministry. The purposeful sampling was carried out, and fifteen clergy participated in the semi-structured interviews. Their responses helped with gaining insights into the themes of God’s grace, suffering, and human flourishing amid suffering. The …

Opiate Addiction Crisis In The United States, Autumn Joy Collins

Doctoral Dissertations and Projects

This research investigates how fentanyl has influenced drug trafficking trends and the corresponding response from law enforcement in New York State. It aims to explore the changes in drug trafficking pathways, organizational structures, and methods in this region since fentanyl's emergence and how state law enforcement has adjusted to this new challenge. The study uses a quantitative methodology, analyzing various data from law enforcement records, court documents, and state government reports. The focus is on fentanyl-related drug trafficking cases in New York State over five years. Methods include examining case records and analyzing trafficking patterns statistically. The study will assess …

Passing The Torch: Evaluating Documentation Quality And Its Impact On Nurses’ Perceptions Of Communication Across Va Care Transitions, Shannon Collier Baker

Doctoral Dissertations and Projects

Effective communication during transitions of care is crucial to ensuring patient safety and optimizing outcomes. However, current practices may fall short in supporting clear and comprehensive communication among healthcare providers, particularly during complex care transitions involving Veterans who have received targeted care coordination intervention outside of their primary Patient Aligned Care Team. The absence of standardized tools for handoff documentation exacerbates fragmented communication and ambiguity about the transfer of care management responsibilities, potentially leading to avoidable errors and care coordination failures. This project aimed to investigate nurses' perceptions of the adequacy of communication during the transition of moderate to complex …

Enhancing Collaborative Care: A Training Manual For Improving Veterans Affairs Mental Health Chaplaincy, Eddie L. Jones

Doctoral Dissertations and Projects

In 2010, the U.S. Department of Veterans Affairs (VA) and the Department of Defense (DoD) launched a study to investigate the integration of chaplains in mental health care. This research expands on that study by focusing on the critical need for enhanced collaboration between chaplaincy and mental health services at local VA facilities. While existing literature affirms the integral role of chaplains in addressing the spiritual and emotional needs of individuals, significant gaps in awareness and effective collaboration practices were identified at the Marion, IL VA Health Care System (VHCS). This study aimed to assess and address the specific training …

Exploring Educators’ Perception Of The Influence Of Social And Emotional Learning Interventions On High School Mathematics: A Case Study, Imaga Eke Idika

Doctoral Dissertations and Projects

The purpose of this multiple-case study was to understand educators' perceptions of the influence of social-emotional learning interventions on students' engagement in high school mathematics in the Alpha School District in the United States. The guiding theory used was Albert Bandura's social learning theory. This theory plays a crucial role in highlighting teachers' classroom activities that elicit observable behavioral changes in learners, which are critical to instruction, learning, and performance. The central research question was: What is educator perception of social-emotional learning interventions in high school mathematics? I conducted the study in four high schools that fully implemented SEL intervention …

The Efficacy Of Mindfulness, Breathwork, And Neurofeedback: A Holistic Approach To Healing, Cheryl Moore-Whidby

Doctoral Dissertations and Projects

The purpose of this phenomenological study is to explore the holistic impact of mindfulness, breathwork, and neurofeedback on individuals experiencing a range of emotional and physical health conditions, including PTSD, anxiety, depression, chronic pain, cardiovascular symptoms, and other chronic illnesses. This investigation is grounded in multiple theoretical frameworks, including the Polyvagal Theory (Porges, 2009), Cognitive Theory (Beck, 1963), Maslow’s Hierarchy of Needs (Maslow et al., 1943), Mindfulness-Based Stress Reduction (Kabat-Zinn, 1990), and Dialectical Behavior Therapy (Linehan, 1993). A total of 28 participants, approved through IRB review, engaged in 24 sessions across 30 days, divided between in-person and virtual formats. Breathwork …

Exploring The Impact Of Special Education Advocates On Service Acquisition For Racially And Ethnically Diverse Families In Virginia K–12 Public Schools: A Hermeneutic Phenomenological Study, Shelesha D. Taylor

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to describe the influence that experienced special education advocates had on the acquisition of special education services for racially and ethnically diverse families with children who have disabilities in Virginia’s K–12 school system. In this study, the influence of an experienced special education advocate was generally defined as the ability to help parents navigate the special education process, advocate for children with disabilities, understand their rights, and obtain appropriate services. Albert Bandura’s self-efficacy theory guided the study. The central research question was: “What are the lived experiences of racially and ethnically diverse …

Comparing The Effects Of Numerical Versus Syllable-Based Pedagogy On Kindergarten Academics, Tocorey C. Johnson

Doctoral Dissertations and Projects

The purpose of this study is to examine the effects of numerically based and syllable-based pedagogical approaches on kindergarten students in a school located in Duval County, Jacksonville, Florida. The Kodály Method, a well-established and effective music education strategy, offers numerous classroom benefits. Teachers can utilize both numerically based and syllable-based approaches within the Kodály framework. However, additional data are required to ascertain whether these approaches can enhance academic performance among kindergarten students. A quasi-experimental design was used to evaluate the effectiveness of syllable-based music training on kindergarten reading scores and numerical-based music training on kindergarten math scores. The initial …

An Analysis Of Sport Science Practices And Standards In Collegiate Football, Corey F. Fitzgerald

Doctoral Dissertations and Projects

This dissertation presents the findings of a survey that identifies the sport science practices and standards utilized in National Collegiate Athletic Association (NCAA) football programs. In total a fifty-two item survey instrument was administered that examines seven sections, including (i) demographics, (ii) current sport science practices, (iii) advanced technology, (iv) decision-making processes, (v) health and wellness, (vi) budget and resources, and (vii) comments. All generated numerical data was organized into a statistical analysis program, SPSS Statistics v 29.0.2.0 (© IBM Corporation). Correlations were conducted on data gathered from Likert Scale questions, using Spearman test. Additionally, comprehensive non-numerical subjective data was …

Exploring The Effectiveness Of Wearable Devices For Early Disease Detection, Chinonso Iwummadu

Doctoral Dissertations and Projects

The purpose of this qualitative interpretive phenomenological study was to explore the perceived effectiveness of wearable devices in facilitating early disease detection among patient groups, healthcare professionals, and healthcare administrators in the outpatient care setting. The central phenomenon investigated, involved the experiences, perceptions, and behavioral responses toward real-time monitoring and diagnostic engagement enabled by wearable devices. The theory that guided the study was the Health Technology Acceptance Model (HTAM), which supported inquiry into how perceived usefulness, perceived ease of use, and perceived health outcomes shaped adoption behavior and clinical integration of digital tools. Data were collected from a purposive sample …

Where Is God In Times Of Order And Disorder: A Practical Approach To Life Events With God, Chinedu Festus Onuigbo

Doctoral Dissertations and Projects

The purpose of this study was to uncover what six next-generation females in Colorado, USA, encompassing high school through post-college, have experienced as they answer the question, "Where is God in times of order and disorder." Next generation refers to persons currently 25 years and younger. Pew Research (2019) reports, next-generation demographic during the transition from adolescence to adulthood may undergo one or more of the following: fall away from faith, question the existence of God, depression, and identity crisis. This researcher using phenomenology explored his Study Concept, a practical approach to experiencing life events with God using threefold biblical …

Excitotoxic Neuronal Death Requires Superoxide Entry Into Neurons Through Volume-Regulated Anion Channels, Kate Harris, Seok Joon Won, Gokhan Uruk, Nguyen Mai, Devran Ogut, Yonghui Zhao, Litao Xie, Paul Baxter, Katharina Everaerts, Rajan Sah, Raymond A Swanson

2020-Current year OA Pubs

Neuronal death in stroke and other conditions stems in part from stimulation of

Adapt-3d: Accelerated Deep Adaptable Processing Of Tissue For 3-Dimensional Fluorescence Tissue Imaging For Research And Clinical Settings, Daniel D Lee, Kevin A Telfer, Deanna L Davis, Leon C D Smyth, Rahul Ravindran, Rafael S Czepielewski, Christopher G Huckstep, Siling Du, Kento Kurashima, Ajay K Jain, Jonathan Kipnis, Bernd H Zinselmeyer, Gwendalyn J Randolph

2020-Current year OA Pubs

Light sheet microscopy and preparative clearing methods that improve light penetration in 3D tissues have revolutionized imaging in biomedical research. Here we present ADAPT-3D, a streamlined 3-step approach to turn tissues optically transparent while preserving tissue architecture with the versatility to handle diverse tissue sizes and types across species. Unlike extensive lipid removal utilized by existing protocols, ADAPT-3D only partially removes lipids to preserve cell membranes, yet the non-toxic aqueous refractive indexing solution still rapidly turns tissues transparent while preserving the fluorescence of endogenous and antibody conjugated fluorophores. ADAPT-3D prepares whole mouse brains for light sheet microscopy in a 4-hour …

Whf Roadmap On Single Pill Combination Therapies, Enrico G Ferro, Mark Huffman, Orly Vardeny, Et Al.

2020-Current year OA Pubs

Cardiovascular diseases (CVDs) are the leading global cause of mortality, with treatment adherence posing a major barrier to effective prevention and control. Single pill combinations (SPCs), also known as fixed-dose combinations, simplify treatment by combining multiple agents into one pill, improving adherence and reducing cardiovascular risk. This World Heart Federation Roadmap synthesizes the latest clinical evidence and identifies key barriers to SPC implementation, including limited manufacturing, affordability, regulatory complexity, and inconsistent guideline inclusion. Drawing on global expert input and health systems analysis, the Roadmap outlines practical, context-specific solutions to improve access, scale-up, and integration of SPCs into national strategies, especially …

Prefoldin Complex Promotes Interferon-Stimulated Gene Expression And Is Inhibited By Rotavirus Vp3, Yinxing Zhu, Yanhua Song, Dilip Kumar, Peter K Jackson, B V Venkataram Prasad, Siyuan Ding

2020-Current year OA Pubs

Timely induction of interferons and interferon-stimulated genes (ISGs) is critical for successful host defense against viral infections. VP3 encoded by rotavirus is implicated in interferon antagonism. However, the precise mechanisms remain incompletely understood. By conducting tandem-affinity purification coupled with high-resolution mass spectrometry, we identify the prefoldin complex as the top cellular binding partner of VP3. Rotavirus infection is significantly enhanced in prefoldin subunit knockout cells. Using proteome-wide label-free quantification, we find that prefoldin assists in folding ubiquitin-like-modifier-activating-enzyme-3 (UBA3), both of which positively regulate ISG expression. Through direct and competitive binding, VP3 interferes with the chaperone activity of prefoldin, leading to …

The Caribbean American Dementia And Aging Study: Protocol For A Population-Based Study Of Older Adult Health And Dementia In Cuba, The Dominican Republic, And Puerto Rico, Mao-Mei Liu, Jorge Llibre-Guerra, Chris Soria, Jing Li, Tania Zayas Llerena, Guillermina Rodriguez, Daisy Acosta, Ivonne Jiménez Velázquez, Juan J Llibre-Rodriguez, William H Dow

2020-Current year OA Pubs

BACKGROUND: The Hispanic Caribbean region is rapidly aging but national population-based aging surveys are rare. The Caribbean American Dementia and Aging Study (CADAS) is a multi-purpose household study of aging with a particular focus on the life course determinants and consequences of health and dementia in three countries with many similarities but divergent recent histories: Puerto Rico, Dominican Republic, and Cuba. METHODS: CADAS will survey population-based samples of adults ages 65 and over. In Puerto Rico and Dominican Republic these will be nationally representative samples of 1,500 adults each; the Cuban survey will include 1,500 adults from purposively selected urban …

A Lesson In Balance: The Duality Of Stat4 In Atherosclerosis And Survival, Alina Moriarty, W. Coles Keeter, Shuchi Vachhani, Natalie Stahr, Cassandra Hyde, Kelly Wai, Shelby Ma, Larry Sanford, Elena Galkina

Cardiovascular Research Symposium

No abstract provided.

Investigating Extracellualr Vesicles Role In The Pathogenesis Of Acute Lung Injury, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Tierney Day, Anca Dobrian, John D. Catravas

Cardiovascular Research Symposium

Background: Extracellular vesicles (EVs) are small lipid-bound particles containing proteins and RNAs, whose role in intercellular communication and signaling is critical for homeostasis or inflammatory responses. Patients with acute lung injury display changes in EVs number, cargo content and signature compared to healthy individuals.

Hypothesis: We have hypothesized that EVs may play a role in the pathogenesis of acute lung, by transferring harmful mediators of inflammation and disrupting recipient cells homeostasis.

Methods: C57BL/6j mice (8-10 weeks old, 25g BW) were intratracheally instilled with 50µL of 5*1010- 11 EVs isolated from Human Lung Microvascular Endothelial cells (HLMVEC) exposed to 1 µg …

The Role Of Iga In Atherosclerosis, Basudha Habisyasi, Alina Moriarty, Shelby Ma, Kathleen Coleman, Sejal Sinha, Jonee Lilliard, Kelly Wai, J. Baodan Collins, Elena Galkina

Cardiovascular Research Symposium

No abstract provided.

Characteristics And Outcomes Of Axillary And Subclavian Artery Injuries, Benjamin Samberg, Nicholas Bandy, Michael Martyak

Cardiovascular Research Symposium

INTRODUCTION: Subclavian and axillary artery injuries are rare but life-threatening. Optimal management strategies remain debated. This study compares injury characteristics and outcomes.

METHODS: Retrospective analysis was conducted on 181 PROOVIT Database patients categorized by injury location, mechanism, and treatment (open, endovascular, nonoperative). Collected data includes ISS, PRBC, mortality, hospital and ICU LOS, and hard signs.

RESULTS: Subclavian injuries had higher ISS (μ=25, 19; p=0.004) and mortality (18%, 3.4%; p=0.004), but fewer hard signs (41%, 63%; p=0.004) than axillary. Axillary injuries were more frequently treated with open repair (51%, 32%; p=0.016), while subclavian injuries were more often managed nonoperatively (45%, 29%; …

B Cell Subset Specific Regulation Via Desmosterol In An Atherosclerotic Environment, Shelby Ma, Alina Morty, Kathleen Coleman, Basudha Habisyasi, Elena Galkina

Cardiovascular Research Symposium

No abstract provided.

Real-World Interventional Outcomes For Cardiogenic Shock Complicating Acute Myocardial Infarction, Zachary Bouker, John E. Brush Jr., Ann M. Harper, Luke C. Kohan, Kaivalya Dandamudi, Deepak R. Talreja

Cardiovascular Research Symposium

No abstract provided.