Digital Commons Network^™

Career Advising Utilization: A Quantitative Archival Analysis Of Student Engagement Across Academic Levels And Colleges At A Southeast University, Edward Raimundi Iii

Electronic Theses and Dissertations

This quantitative ex-post facto study examined patterns of career advising utilization at a large, R1 public university in the southeastern region of the United States. Institutional advising data from the 2023–24 advising year was utilized to identify usage patterns across different demographics such as college affiliation and academic level. The descriptive stats from the archival data were used to measure topic distributions, undergraduate–graduate usage by college, and contact engagement. The sample size included over 35,000 students with 10 different college affiliation labels. Significant differences across advising usage in the different colleges were found during the study. Undergraduate students had higher …

Pre-K Teachers’ Perceptions About Professional Learning: Influence On Instructional Methods, Classroom Management Skills, And Student Outcomes, Victoria Abakah Korsah

Electronic Theses and Dissertations

The purpose of this qualitative descriptive phenomenological study was to solicit pre-K teachers’ perceptions about professional development and its influences on instructional methodology, classroom management skills, and student outcomes. Interviews conducted with 11 teachers from childcare centers in a major urban city of Illinois provided insight into experiences of types of PL and development engagement, such as online courses, webinars, learning communities, coaching, mentoring, professional conferences, and content selection. Other experiences involved social-emotional learning, lesson planning, project-based learning, and how to teach children with special needs. The interview data collected from the participants yielded five themes using Colizzi’s data analysis …

Transformational Leadership Disparities Within Nonprofit Organizations, Hillman Evans Iv

Electronic Theses and Dissertations

Leadership development is a primary organizational development function. It provides an opportunity for professional growth and is essential to assisting personal evolution for individuals in any capacity. This qualitative case study explored incorporating the transformational leadership style in a multilocation nonprofit organization. Eight participants participated in semistructured interviews. Each interview lasted approximately 30–45 minutes. The interview format consisted of asking open-ended semistructured questions and allowing participants to respond based on their organizational experiences. The researcher employed three coding passes in the data analysis (open, axial, and selective) and identified eight themes. The findings suggested that managers desired a leader who …

Underrepresentation Of African American Women Superintendents In The Public Schools Of Texas: Descriptions Of Their Lived Experiences, Shani R. Wyllie

Electronic Theses and Dissertations

The problem addressed through this study was the underrepresentation of African American women superintendents in the public-school districts of Texas, despite women making up a majority of the public-school workforce. The purpose of this transcendental phenomenological study was to describe the lived experiences of African American women superintendents regarding the support and barriers they encountered as they navigated their journeys to the position of public school district superintendent in Texas. The study was grounded in the Black feminist thought framework. Five semistructured interviews were conducted with currently serving African American women superintendents in Texas. The participants had been in the …

Differences In Peer Social Connections Between Traditional And Online Nurse Residency Programs, Tatum Leonard

Electronic Theses and Dissertations

The anticipated retirement of baby boomer nurses by 2030 will intensify the global nursing shortage, a crisis that demands innovative strategies for onboarding and retaining new graduate nurses. Nurse residency programs (NRPs) are designed to ease the transition from student to practicing nurse, reduce turnover, and foster professional resilience. Amid the COVID-19 pandemic, many NRPs rapidly transitioned from traditional, in-person seminars to synchronous, online formats. This study explored differences in peer social connections between traditional and online NRPs, focusing on three constructs: sense of community, collaborative learning, and peer social support. Using a quasi-experimental, mixed methods approach, this secondary data …

Teaching Information Literacy In The Emerging And Dynamic Fields Of Preparedness And Security, Abigail Adams

University Libraries Faculty Scholarship

Emergency preparedness and security are comparatively new academic fields, but they have grown tremendously in the last ten years.1 Colleges and universities all over the United States and Canada are adding and expanding programs dedicated to various facets of these subjects. While the specific subtopics and focal areas can vary by program, they all explore threat assessment, risk management, and disaster mitigation in some capacity. Emergency preparedness or emergency management programs prepare students to pursue careers dealing with crisis mitigation and response, whether that crisis is a result of natural disaster, climate change, war, civil unrest, infrastructure failure, economic instability, …

Assessing The Impact Of Tungiasis On Children's Quality Of Life In Kenya, Lynne Elson, Berrick Otieno, Abneel K. Matharu, Naomi Riithi, Esther Jebor Chongwo, Francis Mutebi, Hermann Feldmeier, Jürgen Krücken, Ulrike Fillinger, Amina Abubakar

All Peer-Reviewed Publications

Tungiasis is a neglected tropical skin disease caused by the sand flea, Tunga penetrans which penetrates the skin causing considerable pain and itching. In this cross-sectional study we aimed to assess its impact on the quality of life of school children in Kenya. School pupils (198) aged 8-14 years with tungiasis were randomly selected and interviewed using a tungiasis-specific quality of life instrument (TLQI). The caregivers of each infected pupil and 199 randomly selected caregivers of uninfected pupils were interviewed using the proxy KIDscreen52 to assess their child's general health-related quality of life (HR-QoL). Generalized linear models were used to …

Government Vicarious Liability And The Concept Of Deemed Equality With Private Persons, Gary K. Y. Chan

Research Collection Yong Pung How School Of Law

The immunity against Crown liability was abolished in the United Kingdom in 1948 based on the Diceyan notion of rule of law and deemed equality under the law between public officials and private persons. This paper analyses government vicarious liability in respect of the acts and omissions of public officers under the Singapore Government Proceedings Act with reference to the concept of deemed equality. We will discuss the scope of the statute in light of recent common law developments in vicarious liability, statutory exceptions to government vicarious liability that may be justified by the functions of the government in the …

Death Penalty For Drug Offenders In Southeast Asia: Weakening Of Resistance To Change?, Wing Cheong Chan

Research Collection Yong Pung How School Of Law

Although the global movement towards abolition of the death penalty has been supported by an increasing number of countries in the world, the number of persons executed for drug offences actually increased in the last few years. Known executions for drug offences now account for more than 40 per cent of all global executions. Most such executions take place in Asia. Of the 34 countries in the world that still retain the death penalty for drug offenders, all nine of those identified as “high application states” (China, Indonesia, Iran, Kuwait, Malaysia, North Korea, Saudi Arabia, Singapore and Vietnam) are found …

Routine Antenatal Ultrasound By Nurse-Midwives In Rural Kenya: A Pragmatic Trial Assessing Feasibility And Effects Of The Mimba Yangu (My Pregnancy) Project, Claudia Hanson, Lucy Nyaga, Nidhi Leekha, Michaela Mantel, Sarah Kedenge, Caroline Gitonga, Violet Naanyu, Jasmit Shah, Marleen Temmerman

Centre of Excellence in Women and Child Health

Introduction: Task-sharing of obstetric ultrasound between nurse-midwives and doctors has the potential to operationalize the World Health Organization’s recommendation of at least one ultrasound before 24 weeks of gestational age for every pregnant woman. Here, we report on the feasibility, acceptability, and effects of the Mimba Yangu (My Pregnancy) task-sharing approach in rural Kenya.

Methods: We conducted a pragmatic trial including 28 primary care facilities between April 2021 and March 2022, selected based on feasibility criteria. Fourteen facilities received the ultrasound intervention composed of (i) task-sharing with nurse-midwives, (ii) the use of portable ultrasound devices (Lumify™) connected to a tablet, …

Engaging Students And Stakeholders In Times Of Crisis: Hbcus Bridging Social Capital On Facebook While Navigating Physical Distancing, Pamela Peters

Journal of Research Initiatives

COVID-19 placed a strain on colleges that tend to rely on tuition, especially small HBCUs, which traditionally serve a high percentage of underrepresented students. Being away from campus, many stakeholders were experiencing higher levels of stress and anxiety. Social media offers an outlet for schools and stakeholders to stay connected during a crisis. Using social capital, this study examined how small HBCUs bridged social capital on Facebook during the year before and the first two years of the pandemic. A comparative analysis of Facebook posts of 30 HBCUs with a student population of under 2000 was conducted to determine post …

How Graduates Of Color Developed Marketable Skills As On-Campus Student Employees, Christopher A. Burnett, Z.W. Taylor

Journal of Research Initiatives

Research on how students of color are employed in on-campus student affairs positions and the development of their marketable skills for post-graduation employment is limited. To address this gap, this study examined the experiences of 12 students of color in student affairs roles. The goal was to understand how these students benefitted from their on-campus employment, developed valuable skills, and secured job opportunities after graduation.

The findings indicate that students of color were able to readily identify and communicate the marketable skills they acquired during their time as students. These skills include management, teamwork facilitation, digital literacy, and the ability …

Multi-Generational Biases Perceived By Women To Senior Leadership Positions In Non-Profit Higher Education, Regina Watkins, Deanna R. Davis

Journal of Research Initiatives

Women remain underrepresented in senior leadership in both public and private industry and in non-profit postsecondary education. One reason that has been identified for the gender disparity in senior leadership positions is second-generation or implicit biases. The problem addressed in this study was the existence and persistence of second-generation biases that contribute to the lack of active senior women mentors, potentially inhibiting junior women from Generation X and millennials from achieving senior leadership status in non-profit higher education. The purpose of this qualitative descriptive case study was to gain a deeper understanding of the significance of perceptions of second-generation biases, …

Pedicle Lengthening Osteotomy For Lumbar Spinal Stenosis: A Systematic Review Of Cadaveric, Computational, And Clinical Outcomes, Jonathan A Ledesma, Julio Castillo Tafur, Bradley Anderson, Lasya Rangavajjula, Mark J Lambrechts, D Greg Anderson

2020-Current year OA Pubs

Study DesignSystematic Review.ObjectiveTo review the available published literature relating to pedicle lengthening osteotomy (PLO) for lumbar spinal stenosis (LSS), and to compare this technique to existing surgical options.MethodsPubMed/MEDLINE, Embase, and Scopus were reviewed using the keywords: "pedicle lengthening", "lumbar", and "spinal stenosis." Results were reviewed for relevance and included only if they met inclusion criteria. The SYRCLE checklist was used to assess for sources of bias.ResultsInclusion criteria were biomechanical or clinical studies evaluating PLO for LSS. A total of 56 studies were identified in the Pubmed/MEDLINE database using the above-mentioned search criteria. Additionally, a total of 83 abstracts were reviewed …

Dual-Vector Raavrh8 Gene Therapy For Gm2 Gangliosidosis: A Phase 1/2 Trial, Florian Eichler, Xuntian Jiang, Et Al.

2020-Current year OA Pubs

The dual rAAVrh8-HEXA and rAAVrh8-HEXB vector can restore central nervous system hexosaminidase (Hex) enzyme activity, decrease GM2 levels in cerebrospinal fluid and rescue phenotypic consequences of GM2 gangliosidosis, Tay-Sachs and Sandhoff diseases in animal models following simultaneous bi-thalamic (BiT) injections. Following up on an n = 2 expanded access trial, we initiated a phase 1/2, single-dose, dose-escalation of combined BiT, intra-cisterna magna and intrathecal infusion in children with Tay-Sachs and Sandhoff diseases (six infantile, three juvenile). The BiT injection volume and vector dose were doubled between four cohorts, with the lowest dose matching the earlier expanded access trial. Cerebrospinal fluid …

Differences In Physician Electronic Health Record Use By Telemedicine Intensity: Evidence From 2 Academic Medical Centers, Seunghwan Kim, Robert Thombley, Elise Eiden, Sunny Lou, Julia Adler-Milstein, Thomas Kannampallil, A Jay Holmgren

2020-Current year OA Pubs

OBJECTIVE: Evaluate the association between telemedicine intensity and ambulatory physician electronic health record (EHR) use following the COVID-19 pandemic.

MATERIALS AND METHODS: This retrospective study included ambulatory physicians in 11 specialties at 2 large academic medical centers (Washington University in St Louis [WashU], University of California San Francisco [UCSF]). EHR use measures, including time-based and frequency-based, were analyzed in the post-COVID-19 period (March 1, 2021, through March 7, 2022). Multivariable regression models with 2-way fixed effects were used to assess the association between telemedicine intensity and EHR use.

RESULTS: Fully telemedicine physician-weeks were associated with higher EHR (hours per 8 …

Nerve-Associated Macrophages Control Adipose Homeostasis Across Lifespan And Restrain Age-Related Inflammation, Elsie Gonzalez-Hurtado, Maxim N Artyomov, Et Al.

2020-Current year OA Pubs

Age-related inflammation or 'inflammaging' increases disease burden and controls lifespan. Adipose tissue macrophages (ATMs) are critical regulators of inflammaging; however, the mechanisms involved are not well understood in part because the molecular identities of niche-specific ATMs are unknown. Using intravascular labeling to exclude circulating myeloid cells followed by single-cell sequencing with orthogonal validation via multiparametric flow cytometry, we define sex-specific changes and diverse populations of resident ATMs through lifespan in mice. Aging led to depletion of vessel-associated macrophages, expansion of lipid-associated macrophages and emergence of a unique subset of CD38

Acad10 And Acad11 Enable Mammalian 4-Hydroxy Acid Lipid Catabolism, Edrees H Rashan, Abigail K Bartlett, Jingying Zhang, Andrew J Smith, Zakery N Baker, Patrick Forny, Peng Yuan, David J Pagliarini, Et Al.

2020-Current year OA Pubs

Fatty acid β-oxidation is a central catabolic pathway with broad health implications. However, various fatty acids, including 4-hydroxy acids (4-HAs), are largely incompatible with β-oxidation machinery before being modified. Here we reveal that two atypical acyl-CoA dehydrogenases, ACAD10 and ACAD11, drive 4-HA catabolism in mice. Unlike other ACADs, ACAD10 and ACAD11 feature kinase domains that phosphorylate the 4-hydroxy position as a requisite step in converting 4-hydroxyacyl-CoAs into conventional 2-enoyl-CoAs. Through cryo-electron microscopy and molecular modeling, we identified an atypical dehydrogenase binding pocket capable of accommodating this phosphorylated intermediate. We further show that ACAD10 is mitochondrial and necessary for catabolizing shorter-chain …

Variation In Recommended Treatment Strategies Among American Surgeons For Actual Adult Traumatic Brachial Plexus Injury Cases, Michele N Christy, Christopher J Dy, R Glenn Gaston, Bryan J Loeffler, Mihir J Desai, Steve K Lee, Harvey Chim, Jeffrey B Friedrich, Sameer K Puri, Jason H Ko, Planet Study Group

2020-Current year OA Pubs

PURPOSE: The surgical management of adult traumatic brachial plexus injuries (BPI) is challenging, with no consensus on optimal strategies. This study aimed to gather preferred reconstructive strategies from BPI surgeons for actual cases from a multicenter cohort to identify areas of agreement.

METHODS: Four case files (history, physical examination, and imaging and electrodiagnostic testing results) were distributed to eight self-designated Level IV expert BPI surgeons in the United States. Each surgeon independently reviewed the cases and provided a preferred reconstructive plan via free text response.

RESULTS: For a pan-plexus case after blunt trauma (67 years old; 3 months from injury): …

S1pr1 Regulates Lymphatic Valve Development And Tertiary Lymphoid Organ Formation In The Ileum, Xin Geng, Gwendalyn J Randolph, Et Al.

2020-Current year OA Pubs

Efficient lymph flow is ensured by lymphatic valves (LVs). The mechanisms that regulate LV development are incompletely understood. Here, we show that the deletion of the GPCR sphingosine 1-phosphate receptor-1 (S1PR1) from lymphatic endothelial cells (LECs) results in fewer LVs. Interestingly, LVs that remained in the terminal ileum-draining lymphatic vessels were specifically dysfunctional. Furthermore, tertiary lymphoid organs (TLOs) formed in the terminal ileum of the mutant mice. TLOs in this location are associated with ileitis in humans and mice. However, mice lacking S1PR1 did not develop obvious characteristics of ileitis. Mechanistically, S1PR1 regulates shear stress signaling and the expression of …

Identifying Care Gaps Along The Hiv Treatment Failure Cascade: A Multistate Analysis Of Viral Load Monitoring, Re-Suppression, And Regimen Switches In Zambia, Kombatende Sikombe, Noelle Le Tourneau, Brian Rice, Jake M. Pry, Sandra Simbeza, Laura K. Beres, Anjali Sharma, Njekwa Mukamba, Alison Wringe, James R. Hargreaves, Jacob Mutale, Carolyn Bolton Moore, Izukanji Sikazwe, Elvin Geng, Aaloke Mody

2020-Current year OA Pubs

BACKGROUND: Timely response to treatment failure is critical for improved outcomes and viral re-suppression among people living with HIV, but care gaps along the treatment failure cascade can occur due to delays by both clients (e.g., retention and adherence) and health systems (e.g., fidelity to viral load [VL] monitoring guidelines). We used multistate analysis to identify drivers of implementation gaps in the treatment failure cascade, including time to HIV VL monitoring, re-suppression, and regimen switches, in Zambia.

METHODS AND FINDINGS: We used national electronic HIV health records to identify adults on antiretroviral therapy (ART) for more than 6 months who …

Machine Learning Feasibility In Cochlear Implant Speech Perception Outcomes-Moving Beyond Single Biomarkers For Cochlear Implant Performance Prediction, Matthew A. Shew, Cole Pavelchek, Andrew Michelson, Amanda Ortmann, Shannon Lefler, Amit Walia, Nedim Durakovic, Alisa Phillips, Ayna Rejepova, Jacques A. Herzog, Phillip Payne, Jay F. Piccirillo, Craig A. Buchman

2020-Current year OA Pubs

OBJECTIVES: Machine learning (ML) is an emerging discipline centered around complex pattern matching and large data-based prediction modeling and can improve precision medicine healthcare. Cochlear implants (CI) are highly effective, however, outcomes vary widely, and accurately predicting speech perception performance outcomes between patients remains a challenge. This study aims to evaluate the ability of ML to predict speech perception performance among CI recipients at 6-month post-implantation using only preoperative variables on one of the largest CI datasets to date, with an emphasis placed on identification of poor performers.

DESIGN: All patients enrolled in the national CI outcome tracking database, HERMES, …

Neutrophils Drive Vascular Occlusion, Tumour Necrosis And Metastasis, Jose M Adrover, Xiao Han, Lijuan Sun, Takeo Fujii, Nicole Sivetz, Juliane Daßler-Plenker, Clary Evans, Jessica Peters, Xue-Yan He, Courtney D Cannon, Won Jin Ho, George Raptis, R Scott Powers, Mikala Egeblad

2020-Current year OA Pubs

Tumour necrosis is associated with poor prognosis in cancer

Acinetobacter Phages Use Distinct Strategies To Breach The Capsule Barrier, Alexis J. Mccalla, Forrest C. Walker, Fabiana Bisaro, Miguel Rodriguez-Anavitate, Anna Johannesman, Gisela Di Venanzio, Mario F. Feldman, Michele Leroux

2020-Current year OA Pubs

Acinetobacter baumannii is an opportunistic pathogen that is a growing threat in hospital settings due to its alarmingly high rates of antibiotic resistance. Alternative therapies are urgently needed to manage the growing burden of untreatable A. baumannii infections. Phage therapy is a promising avenue that has already seen some success in isolated compassionate-use cases, including the famous "Patterson case". Bacterial surface structures are the first determinants of susceptibility to phage infection and play a major role in phage host range. Most A. baumannii strains produce a protective capsule that is highly diverse both in structure and composition, and provides the …

Against Activist Cooperation Agreements, Jennifer O'Hare

Faculty Publications

Shareholder activism is at record levels. In a typical campaign, the activist threatens to launch a proxy fight unless the board of directors agrees to take certain actions to increase shareholder value, such as selling off company assets or replacing the CEO. Increasingly, however, there are no proxy fights. Instead, the activist and the board, behind closed doors, quickly agree to settle. The activist withdraws the proxy fight threat, and, in return, the board appoints individuals designated by the activist to sit on the company board. This "Cooperation Agreement" allows the incumbent di- rectors to keep their positions and allows …

Categorial Declinations & Democracy, Brenner M. Fissell

Faculty Publications

The most contentious action taken by reform prosecutors has been the issuance of categorical declination policies. Opponents decry this as bureaucratic nullification of democratically enacted offenses, while the prosecutors themselves counter that they are responding to the will of their local electorate. Democracy claims, it appears, have taken center stage in this debate, and they are deployed by both sides. How should we think about democracy and categorical declinations? The most comprehensive scholarly work on this subject is a 2021 article by Professor Kerrel Murray. In this essay, I hope to continue the work begun by Murray, offering additional insights …

The Blacker The Berry: Food Environments And Intake Associated With Perinatal Depression And Secondary Breastfeeding Outcomes Among Black Americans In The St. Louis Metropolitan Area, Najjuwah S. Walden

Brown School Graduate Student Theses and Dissertations

The relationship between the food environment, intake, and health is complex. The purpose of this study was to evaluate if food environments in proximity to Black pregnant women in the St. Louis Metropolitan Area were associated with prenatal eating habits and if these eating habits were associated with the risk of developing depressive symptoms in pregnancy and postpartum. The study also aimed to understand if there was a relationship between prenatal eating habits and the decision to breastfeed and if the onset of postpartum depressive symptoms has any effect on this relationship. Due to the importance of nutrient-dense, anti-inflammatory foods …

Chesnutt Library Annual Report 2024-2025, Lawrence Treadwell Iv

Annual Reports

No abstract provided.

Role Of Axial Ligation In The Conformational And Redox Properties Of Cytochromes, Morgan Elisabeth Reik

Dartmouth College Ph.D Dissertations

Heme proteins are crucial for many biological processes including respiration, transport, and catalysis. As electron carriers containing redox active metal centers, their electron transfer (ET) properties are tuned by the protein environment, wherein the reduction potential can be influenced by factors such as heme solvent accessibility, charge, the presence of neighboring redox centers, as well as the identity of the axial ligand. The axial ligand in heme proteins is especially crucial for tuning the electronic properties of the metal center, as it affects the driving force of the reaction. However, the redox properties of heme proteins are further modulated by …

Exploring The Use And Misuse Of Large Language Models, Hezekiah Paul D. Valdez, Faranak Abri, Jade Webb, Thomas H. Austin

Faculty Research, Scholarly, and Creative Activity

Language modeling has evolved from simple rule-based systems into complex assistants capable of tackling a multitude of tasks. State-of-the-art large language models (LLMs) are capable of scoring highly on proficiency benchmarks, and as a result have been deployed across industries to increase productivity and convenience. However, the prolific nature of such tools has provided threat actors with the ability to leverage them for attack development. Our paper describes the current state of LLMs, their availability, and their role in benevolent and malicious applications. In addition, we propose how an LLM can be combined with text-to-speech (TTS) voice cloning to create …