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Host Evolutionary History As A Predictor Of Microbiome Breeding Success, Ciana Lazu

Master's Theses and Capstones

Microbial inoculants present a potential alternative to artificial fertilizers and other chemical products in agriculture, yet microbial products derived from non-native microbes may pose ecological risks or fail to thrive. On the other hand, creating microbial inoculants from local microbes via “microbiome breeding” can be unpredictable. Here, the aquatic plant Lemna minor (duckweed), microbes isolated from duckweed, and microbes isolated from other, co-occurring aquatic plants was used to evaluate if the evolutionary distance between hosts from which microbes are sourced is a predictor of the success in “breeding” locally derived microbiomes to promote duckweed growth. “Microbiome breeding” was performed on …

Increasing The Knowledge Base Of A Novel Fruit Crop, Actinidia Arguta, To Promote Adoption In The Northeastern United States, Zoe Rose Robinson

Master's Theses and Capstones

The unique attributes of kiwiberry (Actinidia arguta (Siebold et Zucc.) Planch ex. Miq) make it a promising high-value fruit crop for the Northeastern United States, although not widely grown in the region. As discussed in Chapter 1, it is likely that some of the barriers to kiwiberry diffusion in the Northeast include basic research gaps (e.g. crop physiology, management, and enterprise analysis), and a lack of farmer-to-farmer communication channels. To address some of these barriers, this thesis reports the results of a Northeast commercial kiwiberry growers survey to provide a portrait of current regional kiwiberry production, and experiments to determine …

The Role Of Liver Macrophages In Viral Liver Pathogenesis, Alexis Brantly, Kyle Yeakle, Michael J. Bouchard, Peter J. Gaskill, Michael R. Nonnemacher

Kimmel Cancer Center Faculty Papers

Liver macrophages play important roles in the pathophysiology of liver fibrosis and hepatocellular carcinoma. However, liver macrophages are a heterogenous population and have differing roles in maintenance of liver function and response in disease. In a healthy liver, macrophages play a critical role in antigen processing, maintaining tolerance to the high levels of gut-derived bacterial products, and regulating inflammation through cytokine response. However, macrophages also play a critical role in liver pathology, specifically in the context of viral infection. The liver is targeted by multiple viruses, including human immunodeficiency virus, hepatitis B virus, and hepatitis C virus, which dysregulate macrophage …

Unplanned Hospitalization Among Advanced Prostate Cancer Patients By Diabetes Status: A Population-Based Study, Amy L. Shaver, Krupa Gandhi, Scott W. Keith, Nikita Nikita, Christopher C. Yang, Felix J. Kim, Hushan Yang, William K. Kelly, Stephen J. Freedland, Grace Lu-Yao

Kimmel Cancer Center Faculty Papers

BACKGROUND: Older adults with advanced prostate cancer and type 2 diabetes mellitus are underrepresented in trials of androgen receptor pathway inhibitors. This study examined changes in unplanned hospitalization rates in patients receiving androgen receptor pathway inhibitors by type 2 diabetes mellitus status and assessed if unplanned hospitalization varies according to androgen receptor pathway inhibitors.

METHODS: This population-based study of advanced prostate cancer patients aged older than 66 years used Surveillance, Epidemiology, and End Results-Medicare data. Prepost androgen receptor pathway inhibitor initiation changes and androgen receptor pathway inhibitor differences in unplanned hospitalization rates were estimated by adjusted incidence rate ratio with …

Balancing Acts: Student Rights, Parental Authority, And State Interests In Modern Sex Education, Linda S. Anderson

Marquette Benefits and Social Welfare Law Review

The article explores the complex interplay between parental rights, state authority, and student interests in the context of sex education in American public schools. It highlights the ongoing tension between abstinence-only and comprehensive sex education approaches, emphasizing the need for a student-centric framework that balances the rights and responsibilities of all stakeholders. The current legal landscape is examined through historical development, seminal court decisions, and recent legislative trends. Empirical evidence is presented to demonstrate the effectiveness of comprehensive sex education in promoting public health and supporting adolescents' development. The article advocates for a framework that incorporates student autonomy, age-appropriate content, …

Legislating Loss: Bereavement And State Level Statutes Across The 50 United States, Julio Montanez

Marquette Benefits and Social Welfare Law Review

Bereavement is an effectively inescapable experience. As such, many interventions (e.g., counseling) exist to support adaptation to life without a loved one. There are also legal interventions—such as laws—that carve out space, time, and resources for dealing with bereavement. Using an approach that blends three methodological techniques (i.e., evidence synthesis, policy surveillance, and grounded theory method), the current study explores the characteristics of bereavement statutes across the United States. Several thematic categories were constructed through exhaustive engagement with the qualitative statutory data: Health (e.g., Hospice), Responding (i.e., First Responding and Final Responding), Work Leave, Education, Observance/Commemoration, Government, and Miscellaneous. The …

Minor League Baseball Players' Ascendance From "Seasonal Apprentices" To Full-Time Baseball Players, Garrett Q. Mcguinness

Hofstra Law Review

This article focuses on the historic ratification and ongoing challenges of the first Collective Bargaining Agreement (CBA) for Minor League Baseball (MiLB) players, signed in 2023, over fifty years after Major League Baseball (MLB) players first secured a CBA. It outlines the long-standing disparities between MiLB and MLB players, including delayed unionization, inadequate salaries, poor housing, limited health benefits, and restricted player mobility under the reserve clause. The article highlights key events leading to the CBA, such as the Senne lawsuit addressing wage violations and the controversial Save America’s Pastime Act, which exempted MiLB players from minimum wage laws. While …

Influence Of Disaster Experience On Farmers’ Livelihood Strategies Under Extreme Climate Events In Guizhou Province, China, Yumei Bai, Huiqing Han, Yuanju Jian

The Philippine Agricultural Scientist

Extreme climate events have emerged as a critical challenge to global agricultural production and farmers’ livelihoods. Climate change not only directly impacts crop yields and quality but also compels farmers to adjust their livelihood strategies to address escalating climate risks. This study aimed to investigate how disaster experiences influence farmers’ choice of livelihood strategies, focusing on post-disaster adjustments to cope with climate risks. Using survey data from 1,066 farmers in Guizhou Province, China, ordinary least squares (OLS) and logit models were employed to explore the influence of disaster experience on livelihood strategies, analyzing the mediating role of risk attitudes and …

Crispr-Cas9 Gene Editing In Tomato: Development And Characterization Under Stress, Jun Guo

Tennessee State University Alumni Theses and Dissertations

Transcription factor (TF) families played essential roles in plant responses to abiotic stress, contributing significantly to stress tolerance and adaptation. The basic helix-loop-helix (bHLH) TF family included 161 members in tomato (Solanum lycopersicum). Previous proteomic analysis identified TF bHLH148 (Solyc01g058670) as being upregulated under aluminum (Al) stress, suggesting a potential role in Al tolerance. To investigate this, CRISPR-Cas9 was used to generate SlbHLH148 knockout mutants in the ‘Black Vernissage’ tomato cultivar. Two homozygous T2 lines, Slbhlh148-1 and Slbhlh148-2, were confirmed to contain frameshift mutations that resulted in truncated proteins lacking the bHLH_AtIBH1_like domain, as shown by protein modeling. Phenotypic evaluation …

Evaluating Early Successional Habitat Selection By Herpetofauna And Pygmy Rattlesnakes In Tennessee, Carlin Frost

Tennessee State University Alumni Theses and Dissertations

Coupled with climate change, global biodiversity declines are exacerbated by increasing anthropogenic pressures and ecosystem destruction. Amphibians and reptiles are particularly vulnerable due to their specific and narrow habitat requirements. In Tennessee, the Western Pygmy Rattlesnake (Sistrurus miliarius streckeri) is classified as Threatened and is primarily associated with floodplains adjacent to early successional habitats (ESH) in the western Interior Plateau ecoregion. These ESH support unique flora and fauna but have declined in recent decades, largely due to urban encroachment and disturbance suppression. Studying snakes is challenging because of their limited activity periods, small home ranges, and low detectability from cryptic …

Polish Adaptation Of The Self-Stigma Of Stuttering Scale: Scale Development And Analysis, Marta Wesierska, Natalia Świsłocka, Katarzyna Węsierska, Michael P. Boyle

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: There is currently no available assessment of self-stigmatization for people who stutter in Polish, and previous research has identified a clear need for such a measure to be implemented in therapy settings. The aim of this study was to adapt the Self-Stigma of Stuttering Scale (4S) to Polish. Method: The study recruited 108 Polish adults who stutter (48.1 % female, 51.9 % male), ranging in age from 18 to 67. Participants were mainly recruited via speech language pathologists (SLPs) and self-help group leaders. Participants completed the Polish translation of the 4S scale, as well as questions on general mental …

Procedures For Rangeland Condition Assessment In The Pilbara And Southern Rangelands 2025, Department Of Primary Industries And Regional Development, Western Australia

Natural resources published reports

This report defines the procedures used in 2025 by DPIRD to complete rangeland condition assessment (RCA) in the Pilbara and southern rangelands region which has predominantly shrub-based pastures. For the rest of the pastoral estate, DPIRD uses the Procedures for RCA in the Kimberley which has grass pastures.

RCA is the process DPIRD uses to make systematic, station-level assessment of rangeland. Rangeland condition considers both the condition of pastures (defined in the ‘Pasture condition guides for the Pilbara’ and ‘Pasture condition guides for the southern rangelands including the Gascoyne, Murchison and Goldfields-Nullarbor’) and soils as determined by erosion, using the …

Procedures For Rangeland Condition Assessment In The Kimberley 2025, Department Of Primary Industries And Regional Development, Western Australia

Natural resources published reports

This report defines the procedures used in 2025 by DPIRD to complete rangeland condition assessment (RCA) in the Kimberley region which has grass-based pastures. For the rest of the pastoral estate, DPIRD uses the Procedures for RCA in the Pilbara and southern rangelands which have predominantly shrub pastures.

RCA is the process DPIRD uses to make systematic, station-level assessment of rangeland. Rangeland condition considers both the condition of pastures (as defined in the 'Pasture condition guide for the Kimberley') and soils as determined by erosion, using the erosion assessment method on pastoral lands in Western Australia. The methods have evolved …

Early Phase Testing Of Functional Imagery Training As An Intervention For Anxiety, Jackie Andrade, D. J. Kavanagh, Carly Bowditch, Emily Mackriel, Emily Ravenshill, Amy Sime, Eleanor Trumfield, Jessica Watts, Jon May

School of Psychology

Cognitive models hypothesize a role for motivated behaviour in anxiety disorders, with safety behaviours leading to exaggerated threat appraisals and increased anticipatory anxiety. Based on the Affective Imagery Theory of Motivation, we propose that increasing motivation for engagement behaviours will reduce motivation for safety behaviours through competition for limited capacity cognitive resources supporting motivational imagery. We hypothesise that imagining successful engagement will reduce anxiety directly, and through promoting subsequent engagement. We present preliminary evidence that functional imagery training (FIT), an intervention that develops and teaches motivational imagery, reduces anxiety. FIT was delivered to undergraduates with anxiety in one session lasting …

Montana Voices Amplified: My Perspective: The World Is Not Unbreakable, Katie Neskey, University Of Montana Rural Institute

Independent Living and Community Participation

RIIC employee Katie Neskey talks about helping her child manage anger and express emotions healthily.

Challenges In Providing Equitable Education For Primary School Students With Learning Disabilities In Zimbabwe: Teachers’ Experiences., Joyce Madzinga

Dissertations

This study examines the challenges primary school teachers in Zimbabwe face when supporting students with learning disabilities (LDs). Many learners with LDs are excluded from adequate classroom support due to systemic, cultural, and resource limitations. Learning disabilities are often under-recognized as compared to other disabilities because they are invisible. Raising awareness and empowering educators are crucial steps toward addressing these hidden needs and ensuring they are recognized and met. Six teachers were interviewed using a qualitative ethnographic approach. Findings reveal obstacles, including insufficient training in special education, limited teaching resources, high pupil-teacher ratios, negative societal attitudes, and poverty-related constraints. Additional …

Mechanistic Insights Into The Neuroprotective Effects Of The Antidepressant Agomelatine In Alzheimer's Disease, Grace Terry

Dissertations, Theses, and Capstone Projects

Alzheimer’s Disease (AD) is a complex neurodegenerative disease that has limited treatment options and no cure. AD is characterized by robust pathology including extracellular amyloid beta plaques, intracellular neurofibrillary tangles, neuronal and synaptic loss, neuroinflammation, and brain atrophy. AD presents with cognitive decline and memory loss but only years after neuropathology has started to accumulate. This robust pathology has made AD difficult to treat and highlights the need for therapeutics that modulate multiple pathways. Agomelatine (AGO) was selected by a high-throughput machine learning drug repurposing algorithm by our collaborator Dr. Lie Xie (Hunter College Dept. of Comp. Sci.) as having …

Investigating The Role Of Early Growth Response 1 (Egr1) Gene In Riluzole-Induced Apoptosis In Osteosarcoma, Syeda Maryam Azeem

Dissertations, Theses, and Capstone Projects

Osteosarcoma is a rare but aggressive bone malignancy most commonly affecting adolescents and young adults (AYA). With 5-year survival rate stagnating over the last four decades despite the advancements in multi-modal therapy, drug repurposing offers a rapid path to new osteosarcoma treatments. Recent studies suggest that Riluzole, a drug approved for amyotrophic lateral sclerosis (ALS), may be repurposed for osteosarcoma treatment due to its ability to slow tumor progression and induce apoptosis. Previously, we have shown that Riluzole increases reactive oxygen species (ROS), activating c-Abl, which phosphorylates YAP in the nucleus. YAP then forms a complex with p73 to enhance …

Brownsville Taught Me: Reframing The Public Memory Of Brownsville’S History, Amyleth J. Vargas

Dissertations, Theses, and Capstone Projects

Brownsville is a small neighborhood in eastern Brooklyn, New York, with a rich activist past. Community leaders and organizers have used the tenets of urban education, Black history, grassroots organizing, and community planning as the bases of their struggles for the expansion of justice and equality for Brownsville residents. This thesis discusses Brownsville’s rich history of activism. I use autoethnography, archival materials, and the theoretical framework of public memory to explore this rich history. The recovered stories about Brownsville that I recount here are designed to dispel misrepresentations of the community that have shaped the public memory of Brownsville. In …

From Stories To Strategy: Oral Histories As Qualitative Evidence For Neighborhood Planning, Randip K. Parhar

Dissertations, Theses, and Capstone Projects

Developments in neighborhood planning have sought more grounded and community- engaged approaches to space and service design. This capstone project examines how oral history recordings can serve as a data source for neighborhood planning. It asks “How can computational methods of analysis be applied to oral history recordings to provide a source of information for neighborhood planning?” using Jamaica, Queens, as a testbed. Using R as a computational tool, the project applies foundational text mining techniques, such as term frequency analysis, n-gram analysis, and topic modeling, to explore patterns and themes within the recorded narratives. These methods can provide a …

The Role Of Parent Psychiatric Symptoms In The Intergenerational Continuity Of Child Neglect: A Prospective Examination, Cody D. Stitzel

Dissertations, Theses, and Capstone Projects

Parental history of childhood neglect is a risk factor for offspring neglect. When a parent and their offspring both experience neglect in childhood, the phenomenon is referred to as the intergenerational continuity of child neglect. Understanding how child neglect is continued from one generation to the next is essential for creating effective interventions and prevention strategies that may help break the cycle. Since links between childhood neglect and heightened risk for various psychiatric symptoms have consistently been identified in research, as well as links between various psychiatric symptoms and heightened risk for child neglect, it may be that parents’ psychiatric …

Britten’S Violin Concerto And His Early Period—Score Analysis And Pacifist Narrative, Magdalena Filipczak

Dissertations, Theses, and Capstone Projects

This dissertation presents a comprehensive study of Benjamin Britten’s Violin Concerto, Op. 15, using the work as a lens through which to examine the composer’s early period. Rather than treating the concerto as a purely technical or stylistic artifact, the study situates it within the broader context of Britten’s formative years, his early artistic circles, the political tensions of the 1930s, and his evolving pacifist stance.

The final third of the dissertation offers a detailed formal and interpretative analysis of the full orchestral score, tracing an expressive arc across the entire work by identifying an idée fixe motif and following …

Behavioral Biomarkers Of Vulnerability In The Aba Model, Nora Ozer

Dissertations, Theses, and Capstone Projects

Anorexia nervosa (AN) is a severe psychiatric disorder with the highest mortality rate among mental health conditions, yet effective biological treatments remain limited. The activity-based anorexia (ABA) paradigm, which combines food restriction with wheel access to model the hyperactivity and self-starvation cycle characteristic of AN, shows considerable individual variability in vulnerability. Understanding what predisposes certain individuals to develop the full ABA phenotype while others remain resilient could inform early intervention strategies for human AN. This study employed continuous behavioral monitoring technology to identify early predictors of vulnerability to activity-based anorexia in mice, with the goal of discovering behavioral biomarkers that …

The Crisis Of Safety, Well-Being, And Belonging Facing Lgbtq Children: Mad/Crip Of Color Critique Towards A Curriculum Of Radical Care, Jameson Goetz

Dissertations, Theses, and Capstone Projects

In this thesis, I turn toward the study of educational experience, defined broadly to include lived experiences both within and outside of formal schooling institutions. I approach curriculum as an ongoing project of self-understanding in which one becomes mobilized for engaged pedagogical action alongside others in the pursuit social justice. I am guided by the following question, foundational to the field of curriculum studies: for those of us who work alongside LGBTQ children, what knowledge is of most worth? Critically reflecting on ways of working alongside LGBTQ children in the pursuit of social justice, I formulate a mad/crip of color …

Investigation Of Motor Neuronal And Circuit Level Mechanistic Determinants Of Spinal Excitability Following Cst Injury, Thelma Bethea

Dissertations, Theses, and Capstone Projects

The corticospinal tract (CST) is the primary descending motor pathway in mammals, essential for precise, dexterous movements, especially in humans and nonhuman primates. Damage to the CST, such as from spinal cord injury (SCI), impairs skilled motor function and triggers maladaptive changes including aberrant proprioceptive afferent sprouting and increased spinal excitability. These changes are closely linked to both muscle weakness and the development of hyperreflexia, compounding the functional deficits. Animal models of SCI are valuable for investigating mechanisms of injury and recovery, though traditional models often limit the ability to isolate circuit-specific contributions. To address this, I employed selective unilateral …

Low-Resource Ecoacoustic Audio Classification, Enis Berk Coban

Dissertations, Theses, and Capstone Projects

Ecoacoustic monitoring via machine learning enables scalable analysis but is often constrained by labeled data scarcity, particularly in remote regions like the Arctic. This thesis confronts low-resource ecoacoustic audio classification by developing and evaluating complementary machine learning methodologies. We introduce EDANSA, the first publicly available, expert- labeled Arctic dataset of its kind, curated via novel active learning, alongside a baseline CNN. We systematically evaluate transfer learning, showing general audio embeddings effectively bootstrap classifiers for challenging Arctic sounds, significantly outperforming direct label mapping. Optimizing label utility, we investigate standard data augmentation and introduce novel audio data valuation via Shapley values, revealing …

Determining Risk Factors And Rate Of Surgery After Collagenase Injections For Dupuytren Contracture, Ryan C. Cha, Juliet S. Chung, Sina Ramtin, Asif M. Ilyas

Department of Orthopaedic Surgery Faculty Papers

Purpose: Collagenase injections are a nonsurgical treatment for Dupuytren contracture, but their long-term effectiveness in preventing surgery remains unclear. This study aimed to evaluate the rate of surgical intervention following collagenase treatment and identify whether specific risk factors increase the likelihood of future surgical correction. Methods: This retrospective cohort study utilized the TriNetX US Collaborative network to identify patients diagnosed with Dupuytren contracture between January 2007 and September 2024. Patients initially treated with collagenase injections were identified using relevant current procedural terminology codes. Procedure-specific current procedural terminology codes were then used to determine which patients underwent a subsequent fasciectomy or …

Non-Linear Heart Rate Variability: Investigating Cardiac Complexity Of Psychopathic Traits, Khaya A. Roach

Dissertations, Theses, and Capstone Projects

Psychopathy is a complex personality disorder characterized by distinct emotional and interpersonal deficits, and affects approximately 25% of the prison population and 4.5% of nonincarcerated populations. The manifestation of psychopathy can be understood through two distinct variants, each demonstrating unique etiological pathways and clinical presentations. Primary psychopathy is characterized by core interpersonal and affective deficits, including shallow emotions and manipulativeness, while demonstrating reduced autonomic responsivity and lower anxiety levels. Secondary psychopathy presents with higher levels of impulsivity, anxiety, and emotional dysregulation, showing stronger associations with various psychopathologies. Treatment outcomes also vary between the variants, with primary psychopaths typically showing poor …

Repurposing Atractylenolide Iii, A Natural Anti-Inflammatory Compound, For Alzheimer’S Disease, Angela M. Steele

Dissertations, Theses, and Capstone Projects

Alzheimer’s disease (AD) is a debilitating neurological condition ranked as the fifth leading cause of death in adults over the age of 65. Despite the severity, 98% of drugs have failed as treatments for AD. Current novel drug development approaches have been unable to produce a disease-modifying treatment as they often have a one-target approach, not accounting for the complex nature of the disease. One of the hallmarks of the disease, inflammation, may provide a better target for treatment because it interacts with multiple facets of the disease. Drug repurposing to identify compounds that mitigate inflammation in AD could provide …

Scripted For Surveillance: Parole Revocation Hearings And The Performance Of Procedure In New York, Kelsey G. Greeff

Dissertations, Theses, and Capstone Projects

This thesis examines parole revocation hearings in New York as complex performances that extend carceral control beyond prison walls. Drawing on a composite vignette from the Bronx parole court, it analyzes the interplay between procedural reform, constitutional due process, and neoliberal governance. Using a dramaturgical framework informed by Michel Foucault’s discourse analysis and Judith Butler’s theory of performativity, the study identifies four interrelated processes: the judge as director, who orchestrates hearings according to institutional priorities; normalization, where repetition embeds structural inequality as routine; type-marking, the classification of parolees into predefined roles through accumulated records and cues; and the extension of …