Digital Commons Network^™

Selenoprotein P And Selenium As Potential Diagnostic Biomarkers For Breast Cancer Patients, Farah A. Rashid, Rawaa A. Ali, Hanaa A. Ali

Karbala International Journal of Modern Science

Breast cancer incidence increases in last decade. Oxidative stress increases during cancer development causes consuming of antioxidants. Selenium and its transporting protein, selenoprotein P have an important role in redox homeostasis. This study aims to investigate whether or not selenium and selenoprotein P could be diagnostic biomarkers for breast cancer patients. This study was included 30 individuals in control group who is age- and BMI-matched with 60 breast cancer patients. Selenium was measured by colorimetric assay kit and selenoprotein P was determined by Sandwich ELISA kits. The results indicate significant decrease (p < 0.0001) of serum selenium and selenoprotein P in breast cancer patients compared to control. A positive significant correlation (r = 0.6214, p < 0.0001) was found between selenium and selenoprotein P in breast cancer patients. Selenium has an excellent diagnostic accuracy with area under curve 0.9831, sensitivity 95% and specificity 100% at cut-off less than 3.54 mmol/L. Furthermore, selenoprotein P has also an excellent area under curve 0.9958 with sensitivity 96.77% and specificity 100% at cut-off less than 4.15 ng/ml. These exploratory findings appear that selenium and selenoprotein P could be potential diagnostic biomarkers for breast cancer patients. Further investigations in large-multicenter populations are needed to confirm results.

Lived Experiences Of Emotional Competence Development Among Online Doctoral Clinical Psychology Students During Clinical Training, Michelle Davis

Walden Dissertations and Doctoral Studies

Emotional competence is essential for effective clinical practice, professional development, and client care. However, limited research has examined how emotional competence develops among students in fully online doctoral clinical psychology programs. This qualitative descriptive phenomenological study explored how students enrolled in online doctoral clinical psychology programs experience the development of emotional competence during clinical field training. Guided by Goleman’s emotional competence framework, the lived experiences of doctoral students as they developed emotional awareness, emotional regulation, empathy, and relationship management skills was examined. Data were collected through semistructured interviews with 10 purposively selected participants enrolled in online doctoral clinical psychology programs …

The Truths Beneath The Story: Internal Conflict, Catharsis, And Psychological Allegory As The Catalyst For Transformation In Screenwriting, Heather Bixler

Masters Theses

The Tour is a psychological coming-of-age screenplay that constructs meaning through the interaction of the main character's internal contradictions, resulting in an emotionally and structurally driven transformation. The screenplay is an original feature-length screenplay that follows Claudia, a 17-year-old girl who finds herself in the Unknown World. There she meets The Heartmaker and discovers her heart is missing. She journeys to Pineville, a town that mirrors her life back home, where her late father is still alive, and the townspeople reflect hidden truths of those she loves. The Tour is a coming-of-age psychological drama with allegorical dimensions. The script explores …

Murder Of A Creative: Mfa Thesis, Himani Sanjeevkumar Mehta

Masters Theses

In the creative industry, the phrase “fast-paced environment” is often treated as an essential ingredient for productivity and success. The contemporary design landscape operates within an output-driven system that prioritizes speed, visibility, and measurable worth, contributing to the growing commercialization of creativity. Within this framework, the creative process is often diminished or overlooked where it no longer serves efficiency, reducing creativity to a consumable outcome rather than a reflective and sustaining practice. As a result, creative professionals and students increasingly experience creative anxiety, burnout, and paralysis, alongside imposter syndrome, perfectionism, and self-doubt. These conditions are rarely examined as systemic outcomes …

Shattered Glass: Finding Anna In The Brokenness, Tracy A. Scoville

Masters Theses

This thesis began years ago when I started a novel about a woman that suffered with a mental illness. The story grew into part of a novel. Within the artist’s statement, I present a view of mental illness that I filter through my own experiences. I examine Anna’s struggles with how she thinks, acts and processes stress through a lens of bipolar II disorder. The critical paper examines the importance of dialogue and the need for it to fit the individual characters. The story of Anna, with the use of good dialogue, comes to life in the creative manuscript Shattered …

Constructing Authority: Narrative Craft And The Making Of Meaning In Creative Nonfiction, Lindsay Erin Hickman

Masters Theses

What is this world without stories? Without truth and the sharing of knowledge for those that come after us? As a Christian, I see the Bible as the most influential narrative in my life and imagination. The Bible is filled with facts, lists and information we can verify, but that does not make it any less creative. How can one read the Bible and not see God’s creativity not only in creation, but in every word? Psalms 139: 13-15 states, “For thou hast possessed my reins: thou hast covered me in my mother's womb. I will praise thee; for I …

In Re: Avandia Marketing

2026 Decisions

USDC for the Eastern District of Pennsylvania

Gestational Exposure To Bisphenols And Perceived Stress Predict Dna Methylation Changes In Mothers And Newborn Infants, Samantha C. Lauby, Ariel Bellatin, Mariah L. Deserisy, Julianne C. Botelho, Antonia M. Calafat, Beatrice Beebe, Julie B. Herbstman, Amy E. Margolis, Frances A. Champagne

Human Biology Open Access Pre-Prints

Bisphenols, including bisphenol A (BPA) and “BPA-free” substitute chemicals (e.g., bisphenol S (BPS), bisphenol F (BPF)), are often used in the manufacture of water bottles, food storage containers, lining of tin cans, and thermal paper. Gestational exposure to bisphenols has been associated with poor neurodevelopmental and mental health outcomes in children that are often sex specific. Moreover, there is often a co-occurrence of chemical exposures and chronic stress, such that individuals living in the context of economic disadvantage and associated chronic stress often bear the burden of elevated chemical exposures. Changes in DNA methylation (DNAm) in response to environmental exposures …

July 21, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Association Between Resource Availability And Wellbeing Of Autism Patients In Ghana, Kwabena Aduse-Poku

Walden Dissertations and Doctoral Studies

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that presents significant challenges for children and families in Ghana, where resources remain limited. Grounded in the social ecological model, this quantitative cross-sectional study examined the associations between autism management programs and wellbeing, defined briefly as independent functioning in daily life and learning of autism patients enrolled in selected institutions in Accra and Kumasi, Ghana. Data were collected from N=122 autism patients using structured questionnaires that were completed by caregivers and program staff. Binary logistic regression analyses were conducted to assess relationships between program type, regional location, and years of enrollment and …

Association Between Opioids And Leukemia/Lymphoma In Adults Living In The United States, Brenda Sue Newberry-Colasanti

Walden Dissertations and Doctoral Studies

Opioid prescribing rates and opioid misuse remain high throughout the United States. Exposure to opioids has been positively associated with various cancers; however, research evaluating associations between opioid exposure and hematologic cancers like leukemia and lymphoma is limited. Using the Socio- Ecological Model as a foundation, this quantitative cross-sectional study aimed to analyze the association between medicinal opioid use, opioid misuse, and leukemia/lymphoma while exploring how selected social determinants of health (SDOH) may modify that relationship. Secondary data were pooled from the 2015–20-year United States National Survey on Drug Use and Health (NSDUH). One thousand three hundred and twenty binary …

Effective Work-Life Balance Strategies That Small Business Owners Use To Increase Personal And Organizational Resilience, Anquinett Pope

Walden Dissertations and Doctoral Studies

Small business owners frequently sustain their businesses at the cost of their personal health, which poses long-term threats to both organizational sustainability and resilience. The sustainability of a small business is often inseparable from the health, well-being, and decision-making capacity of its owner. The purpose of this qualitative single case study was to identify and explore effective strategies employed by some small business owners to balance personal and professional obligations to enhance business sustainability. The study was focused on one small business owner from a consulting firm based in the United Kingdom. The project was grounded in the Baldrige excellence …

Differentiating And Accommodating Ocd And Anxiety In Mathematical Contexts, Madeline F. Gavares

Interdivisional Studies Summer Fellows

Students in mathematics classrooms may experience emotional and cognitive challenges that affect how they engage with coursework and assessments. While math anxiety has been widely documented, less attention has been given to how obsessive-compulsive disorder (OCD), particularly checking behaviors, may influence students’ experiences in math settings. This study explores how students who report math anxiety and those who report OCD symptoms describe their engagement with math tasks and test-taking. Drawing on survey and interview data from students and teachers, this study examines how these experiences are articulated and perceived in academic math contexts, rather than evaluating ability or outcomes. By …

Wellness Literature Review – 2025, Martin Huecker, Brian A. Ferguson

Journal of Wellness

Introduction: Clinician well-being remains a persistent challenge, with ongoing burnout and psychological distress despite efforts by systems and individuals. This Journal of Wellness annual review covers studies published in 2025.

Methods: The Editors searched PubMed and Google Scholar for prospective and interventional studies / clinical trials in humans, with focus on well-being. Authors utilized artificial intelligence (AI)–based large language model (LLM) (ChatGPT, OpenAI^TM) to assist with preliminary identification of relevant studies, however authors noted significant AI-associated errors and outright misrepresentations requiring hand curated product generation and manual PubMed searches.

Literature in Review: We continue to appreciate a shift …

Pit Stop: Improving Resuscitation Efforts Within A Level Iv Nicu, Sierra Pharr, Kendall Shaw, Hannah Biscardi

2025

No abstract provided.

Health Literacy And Diabetes Self-Care Behavior, Eucharia Amaefule

Walden Dissertations and Doctoral Studies

Limited health literacy is a significant barrier to effective diabetes self-management among adults with type 2 diabetes mellitus (T2DM), yet nationally representative evidence using comprehensive health literacy measures remains limited. Guided by the health belief model, the purpose of this quantitative, secondary data analysis using cross-sectional data was to examine the relationship between health literacy and diabetes self-care behaviors among U.S. adults with T2DM and determine whether education level moderated this relationship. Data from the 2016 Behavioral Risk Factor Surveillance System were analyzed for U.S. adults (N = 9, 535) with self-reported T2DM. Diabetes self-care behaviors included blood glucose monitoring, …

High School Educational Leaders’ Perceptions On College And Career Readiness Programs, Sabrina Cosey-Davis

Walden Dissertations and Doctoral Studies

The problem that was addressed through this study is that despite the widespread availability of college and career readiness (CCR) programs in high schools, these programs are inconsistently designed, implemented, and aligned at the school level. Grounded in Conley’s CCR framework, the purpose of this study was to explore high school educational leaders’ perceptions on the design, implementation, and alignment of CCR programs within their schools. For this basic qualitative design, data were collected through semistructured interviews with 15 educational leaders including administrators, counselors, and department heads. Data were analyzed using Braun and Clarke’s six-phase thematic analysis with the following …

A Program Proposal For A Leadership-Driven, Evidence-Based, Intentional Rounding Playbook, Jacqueline Butler Brown

Walden Dissertations and Doctoral Studies

Patient experience is a key indicator of healthcare quality. In an acute care hospital in Northeast Georgia, intentional rounding is an established practice. Inconsistent communication, variable leadership engagement, and limited accountability are practice gaps that have reduced its effectiveness in improving patient experience outcomes. A comprehensive literature review using PubMed, CINAHL, MEDLINE, and the Cochrane Library yielded 15 peer-reviewed studies that consistently support intentional rounding as an evidence-based strategy for improving patient satisfaction. As the team leader for this Executive Leadership System Improvement Project, I proposed the development of an Evidence-Based, Leader-Driven Intentional Rounding Program Playbook to standardize enhanced rounding …

Effects Of A Mobile Web-Based Video Patient Education Program On Anesthesia And Recovery, Sinjung Jung, Eun-Hyun Lee, Chun-Ja Kim, Ji Yea Lee

International Nursing Research Congress (INRC)

Background and Purpose: Patients awaiting surgery often experience fear and anxiety related to limited information about surgery, concern about not waking up from anesthesia, uncertainty, surgical outcomes, and postoperative pain [1-3]. Preoperative education has been shown to improve these psychological problems [4, 5], and video-based education in particular is increasingly recognized as an effective teaching tool [1]. However, most preoperative education interventions primarily focus on the surgery itself, and rarely directly address major anesthesia-related issues, such as anesthesia safety or postoperative pain [6]. Therefore, in this study, we developed a mobile web-based video education program on general anesthesia and recovery, …

Barriers And Facilitators To Family Engagement In Critical Care, Brigitte S. Cypress

International Nursing Research Congress (INRC)

Background: Family engagement in care for critically ill patients remains an inconsistent practice and an understudied area of nursing science. Rounds for this study are an interdisciplinary activity conducted at the bedside in partnership with patients, their families, and the healthcare professionals involved in providing the care.

Aim of the Study: We sought to explore and describe the facilitators and barriers to family engagement during patient and family-centered interdisciplinary rounds in the intensive care unit.

Methods: This qualitative exploratory study is part of a multisite experimental study (#Pro2020001614; NCT05449990). We analyzed the narrative data from the qualitative questions added to …

Severe Hypertension In Postpartum: How A Nurse Driven Protocol Can Decrease A Delay In Treatment, Kayleigh Momme

International Nursing Research Congress (INRC)

Severe hypertension in the postpartum period is a significant contributor to maternal morbidity and mortality, affecting up to 10% of pregnancies. Prompt and standardized treatment of severe blood pressure elevations is critical to prevent complications such as stroke, heart failure, and eclampsia. At the practicum site, delays were identified in administering intravenous (IV) antihypertensive medications due to reliance on resident physicians to give the medication, resulting in inconsistent and prolonged treatment times. The purpose of this quality improvement project was to implement an evidence-based nurse-driven protocol for administering IV antihypertensives to postpartum patients with severe hypertension, defined as systolic blood …

Wait! Do Longer Wait Times Lead To Preventable Harm?, Jamie L. Warg, Dawn Bowker

International Nursing Research Congress (INRC)

Background: Since the onset of COVID-19 in 2020, hospitals have experienced significant increases in Emergency Department (ED) wait times and extended hospitalizations. These delays have led to capacity challenges, with patients often held in the ED due to the unavailability of inpatient beds. Prolonged ED stays may increase the risk of preventable patient harm. As Pak et al. (2021) noted, “wait time estimates are critical for delivering safe, effective care to patients in an emergency department.”

Research Aim: This study aims to examine whether prolonged ED stays (greater than 3 hours) are associated with an increased incidence of preventable patient …

A Phenomenological Study On Secondary School Leadership Perceptions Of Self Efficacy Based On Student Vaping Infractions, Tara N. Carter

Doctoral Dissertations and Projects

The intent of this qualitative phenomenological study is to explore how secondary school leadership perceive their self-efficacy in regard to overseeing student vaping infractions. Youth vaping has grown in the past few years, leading to an increased presence in school communities. Adolescents are faced with electronic vaping through a variety of interactions during the school day, expanding on opportunities to vape. In response o the uptick in “at-school” vaping, secondary school leaders are now tasked with responding to this growing influx in addition to other duties and demands within their job role. In addition to overseeing disciplinary measures for students …

A Cross To Bear: Examining Nonadaptive Manifestations Of Secondary Trauma In Professional School Counselors, Byron Ronaldo Kellam

Doctoral Dissertations and Projects

This interpretative phenomenological study was to understand the lived experiences of vicarious trauma among Professional School Counselors working in urban and rural school districts in the southeastern United States. Professional School Counselors are routinely subjected to children’s traumatic histories, positioning them at elevated danger for secondary psychological distress, burnout, and emotional exhaustion. Although increased awareness of vicarious trauma in helping professions is prevalent, inadequate research has examined how Professional School Counselors translate and reconcile the significance of these experiences within school-oriented contexts. The primary theory guiding the study was Constructivist Self-Development Theory. This theoretical framework synchronizes with the research’s attending …

Exploring Nursing Students' Experiences Of Simulation-Based Learning In Developing Critical Thinking, Clinical Reasoning And Clinical Judgment In The Management Of Mental Health Patients: A Qualitative Case Study, Irene Bellew

Doctoral Dissertations and Projects

The purpose of this case study was to explore how simulation-based learning experiences shape the development of critical thinking, clinical reasoning, and clinical judgment for associate degree nursing students when caring for patients with mental health needs. It addressed the need to narrow the gap between theoretical knowledge and practical application in clinical settings, enhancing the preparedness of novice nurses. By positioning nurse educators as facilitators of innovative strategies, this study advocates for the integration of simulation-based learning within nursing curricula. Roy’s adaptation model guided the study, and data were collected through observation of simulation sessions, semi-structured interviews, and reflective …

Coordinating Meaning With Ai System Cards: A Thematic Analysis, Jennifer Rene French Cyrek

Doctoral Dissertations and Projects

As the meaning of AI risk remains unsettled across sociotechnical and public discourse, AI system cards are an emergent, yet understudied, genre of technical documentation through which AI technology developers publicly frame new AI system capabilities including risks. This thematic content analysis study examines how AI technology developers coordinate meaning regarding risk and responsible development in stewardship of AI. Guided by a constitutive view of communication and systems theory, second-order cybernetics, and the cybernetic tradition, this study analyzes a purposive corpus of AI system cards collected from 2023-2025 using thematic content analysis and the hierarchy of meaning heuristic from coordinated …

The Role Of School Climate In Predicting Student Achievement: A Predictive, Correlational Study, Chesney Alexandria Rutherford

Doctoral Dissertations and Projects

The purpose of this quantitative, non-experimental, predictive, correlational study was to determine if school climate foresees student achievement through a predictive correlational design. This study is important because of the examination of how changes in school climate can affect students both academically and psychologically. The convenience sample for this study consisted of a total of 240 participants from 2 different schools in both urban and rural areas of Eastern Tennessee. The participants consisted of 120 sophomores per school enrolled in English II. The setting was the English II classrooms within both schools. The Education School Climate Survey developed by the …

The Protective Factors Of Alcohol Use And Problem Drinking By Emerging Adults During The 2020s And The Era Of Covid-19, Aubrey A. Coplon

Doctoral Dissertations and Projects

This research investigated the protective factors that shape alcohol use and problem drinking among emerging adults during the 2020s, with a spotlight on the COVID-19 pandemic. As this age group grapples with the complexities of self-discovery and independence, the pandemic introduced a new set of challenges and shifts. Through qualitative interviews, this study worked to uncover the resilience strategies and support systems that have emerged as crucial in mitigating alcohol misuse. It examined the role of social connections, mental health resources, coping mechanisms, and evolving social norms in buffering against problem drinking. While the pandemic intensified some risks, it also …

Exploring The Motivations And Educational Needs For Undergraduate Nursing Students To Enter Into Critical Care: A Qualitative Study., Christina S. Pradhan

Doctoral Dissertations and Projects

Critical care nursing is a specialty that demands a high level of skill and dedication. In this high-stress, fast-paced environment, nurses must think fast and act decisively with sound clinical judgment and knowledge. The purpose of this hermeneutic phenomenological qualitative study was to understand the motivating factors that cause nurses to enter the field of critical care, as well as to explore the ways in which undergraduate nursing studies may be improved to better prepare future critical care nurses. Knowles’ adult learning theory was well suited for nursing students bound for a critical care path. Students at two different baccalaureate …

The Lived Experiences Of School Counselors In Counselor Education And Supervision Doctoral Programs: A Phenomenological Study Of Self-Efficacy And Professional Identity, Bryana Lynn Caviness

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to explore the perceived impact of doctoral studies on self-efficacy for school counselors who have earned a Doctor of Philosophy (PhD) in Counselor Education and Supervision (CES) from CACREP-accredited programs. The theory guiding this study is Bandura’s Self-Efficacy Theory as it emphasizes the role of beliefs in one’s capabilities to manage prospective situations. This study sought to understand the lived experiences of these professionals and how their doctoral education influenced their confidence in performing the multifaceted roles of school counseling. By capturing these lived experiences, the study aimed to identify both the strengths …