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Minutes From The September 4, 2025 Meeting Of The University Of Montana Faculty, University Of Montana--Missoula. Faculty

University of Montana Faculty Senate Meeting Minutes

Meeting minutes from the September 4, 2025 meeting of the University of Montana faculty.

The Development Of The Assessment Of Self-Care (Asc), Ashley R. Righetti

Clinical Psychology Dissertations

Self-care is a topic that has piqued the interest of researchers in recent years with much of the focus being on specific subsets of the population such as helping professions and those with chronic conditions. This trend has been consistent when it comes to the development of measures intended to evaluate people’s self-care practices. Designed with Butler and colleagues’ (2019) self-care model in mind, the Assessment of Self-Care (ASC) was developed to broadly assess self-care practices in the general U.S. adult population. This study discusses the development and initial validation of the ASC. After the item generation phase, exploratory factor …

Families Experiencing Domestic Violence Related Homelessness, Brittany Miller

Walden Dissertations and Doctoral Studies

Homelessness in the United States remains a persistent issue despite legislative efforts to address it. Single parents navigating homelessness encounter unique challenges in accessing stable housing and essential services, with domestic violence often serving as a significant contributory factor. The purpose of this qualitative study was to explore the perceptions of practitioners regarding the needs of single parents navigating domestic violence-related homelessness. The empowerment theory provided the framework for this study, and data were obtained from focus groups with leaders and administrators who work in the areas of homelessness, economic security, and family violence. The study’s findings revealed significant gaps …

Staff Education On Nonpharmacological Strategies To Reduce Restraint Use., Abigail Addo

Walden Dissertations and Doctoral Studies

Summary This Doctor of Nursing Practice (DNP) staff education project aimed to reduce the use of physical restraints in hospitalized psychiatric patients by training clinical staff in nonpharmacological strategies, specifically active listening and handholding. Despite regulatory guidelines and ethical concerns, physical restraint remains a common practice in acute care settings, often resulting in physical harm, psychological trauma, and a breakdown in the therapeutic relationship. The practice-focused question guiding the project was: How does education on nonpharmacological strategies impact a change in knowledge and attitudes to promote the reduction of restraint use among hospitalized patients exhibiting psychiatric symptoms? Thirty-one staff members …

Montana Kaimin, September 4, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Kenyon Collegian - September 4, 2025

The Kenyon Collegian

No abstract provided.

Policy Briefing | Responding To Homelessness And Severe Mental Illness In Nyc’S Subways And Other Public Spaces, Center For New York City And State Law

Center for New York City Law

Thursday, September 4

PANELISTS:

Omar Fattal, M.D., System Chief of Behavioral Health, NYC Health + Hospitals

Jeremy Feigelson, Senior Advisor, Metropolitan Transportation Authority

Ozioma Offor, RN, NYC Department of Homeless Services

Brian Stettin, J.D., Senior Advisor for Severe Mental Illness, Office of the Mayor

Cassandra White-Hemphill, Deputy Commissioner, NYC Department of Homeless Services

Human Adipose Stem Cell-Derived Small Extracellular Vesicles Modulate Glial Cell Response In Aged And Young Tbi Mouse Models, Salma S. Abdelmaboud

USF Tampa Graduate Theses and Dissertations

Traumatic brain injury (TBI) is a leading cause of long-term neurological impairment, with aging significantly increasing vulnerability and worsening outcomes. Older individuals experience greater cognitive and motor deficits after TBI and often show diminished responses to therapeutic interventions. Both aging and TBI independently promote heightened neuroinflammation and cognitive dysfunction, increasing susceptibility to poor recovery. This study investigated the therapeutic potential of small extracellular vesicles (sEVs) derived from human adipose-derived stem cells (hASCs) to promote neurological recovery and modulate neuroinflammation in a mouse model of TBI. Male C57BL/6 mice aged 3, 15, and 20 months underwent controlled cortical impact (CCI) and …

Lewy Body Dementia Promotion By Air Pollutants, Xiaodi Zhang, Haiqing Liu, Xiao Wu, Longgang Jia, Kundlik Gadhave, Lena Wang, Kevin Zhang, Hanyu Li, Rong Chen, Ramhari Kumbhar, Ning Wang, Chantelle E Terrillion, Bong Gu Kang, Bin Bai, Minhan Park, Ma Cristine Faye Denna, Shu Zhang, Wenqiang Zheng, Denghui Ye, Xiaoli Rong, Liu Yang, Lili Niu, Han Seok Ko, Weiyi Peng, Lingtao Jin, Mingyao Ying, Liana S Rosenthal, David W Nauen, Alex Pantelyat, Mahima Kaur, Kezia Irene, Liuhua Shi, Rahel Feleke, Sonia García-Ruiz, Mina Ryten, Valina L Dawson, Francesca Dominici, Rodney J Weber, Xuan Zhang, Pengfei Liu, Ted M Dawson, Shizhong Han, Xiaobo Mao

Faculty, Staff and Student Publications

Evidence links air pollution to dementia, yet its role in Lewy body dementia (LBD) remains unclear. Here we showed in a cohort of 56.5 million individuals across the U.S. that PM2.5 exposure raises LBD risk. Mechanistically, we found PM2.5 exposure led to brain atrophy in wild-type mice, an effect not seen in α-synuclein (αSyn)-deficient mice. PM2.5 exposure generated a highly pathogenic αSyn strain, PM-PFF, with enhanced proteinase K-resistance and neurotoxicity, resembling αSyn LBD strains. PM2.5 samples from China, the U.S., and Europe consistently induced proteinase-resistant αSyn strains and in vivo pathology. Transcriptomic analyses revealed shared responses between PM2.5-exposed mice and …

Dissecting Microbial Communities With Single-Cell Transcriptome Analysis, Andrew W Pountain, Itai Yanai

Faculty, Staff and Student Publications

Revealing insights into the function of microbial communities requires moving beyond measuring bulk taxonomic composition to detecting interactions between subpopulations. Following the transformative impact of single-cell gene expression profiling techniques on numerous fields of human biology, recent years have seen increased application to microbes. We review progress in the development of these techniques and discuss challenges in applying them to microbial communities. We highlight applications for dissecting the microbiome in human health and disease that reveal functional heterogeneity within gut communities, antibiotic responses, and the dynamics of mobile genetic elements. As single-cell gene expression technologies continue to develop, they are …

Human Papillomavirus Integration Induces Oncogenic Host Gene Fusions In Oropharyngeal Cancers, Nusrat Khan, Keiko Akagi, Shiming Jiang, Joe Dan Dunn, Bo Jiang, Weihong Xiao, Madison P O'Hara, Li Shen, Qi Wang, Vakul Mohanty, Jing Wang, Sara Goodwin, Jamie L Hutchins, Kevin R Coombes, Jagannadha K Sastry, David E Symer, Maura L Gillison

Faculty, Staff and Student Publications

HPV integration disrupts host genomic structure and expression, but whether these alterations promote cancer development remains unclear. Multiple genomic analyses of oropharyngeal cancers identified several host fusion genes, including recurrent FGFR3-TACC3 fusions, expressed from rearranged genomic loci adjacent to HPV integration sites. Evolutionary modeling implicated integration of virus concatemers into the host genome as a common initiating event in fusion formation. Co-expression of HPV16 E6/E7 and FGFR3-TACC3, but neither alone, was sufficient for tumor development in both xenograft and syngeneic mouse models and led to unique transcriptional programs implicated in carcinogenesis. FGFR3-TACC3 expression decreased the ubiquitination and degradation of …

Detection Of Cancers Three Years Prior To Diagnosis Using Plasma Cell-Free Dna, Yuxuan Wang, Corinne E Joshu, Samuel D Curtis, Christopher Douville, Vernon A Burk, Meng Ru, Maria Popoli, Janine Ptak, Lisa Dobbyn, Natalie Silliman, Josef Coresh, Eric Boerwinkle, Anna Prizment, Chetan Bettegowda, Kenneth W Kinzler, Nickolas Papadopoulos, Elizabeth A Platz, Bert Vogelstein

Faculty, Staff and Student Publications

To explore how early can cancers be detected prior to clinical signs or symptoms, we assessed prospectively collected serial plasma samples from the Atherosclerosis Risk in Communities (ARIC) study, including 26 participants diagnosed with cancer and 26 matched controls. At the index time point, eight of these 52 participants scored positively with a multicancer early detection (MCED) test. All eight participants were diagnosed with cancer within 4 months after blood collection. In six of these 8 participants, we were able to assess an earlier plasma sample collected 3.1 to 3.5 years prior to clinical diagnosis. In four of these six …

Quaker Campus, September 4, 2025 (Vol. 24, Issue 1), Whittier College

Quaker Campus

No abstract provided.

An Investigation Of Sex-Specific Effects Of Nucleus Accumbens Dopamine Receptor Signaling In Persistent Reward Seeking Under Punishment, Anna Caroline Toburen

Theses and Dissertations

Addiction involves persistent reward-seeking behavior despite adverse outcomes, with the nucleus accumbens (NAc) critically mediating motivation and cost-benefit decision-making. Dopamine (DA)-responsive neurons in the NAc, specifically D1 and D2 receptors within the NAc are crucial in encoding motivated behavior. However, the specific role of D1/D2 receptors in driving reward-seeking under punishment remains unclear. Preliminary findings suggest a sex-specific effect, with females exhibiting greater sensitivity to the suppressive effects of footshock on natural reward-seeking compared to males. We investigated the differential roles of NAc D1/D2 receptors in modulating reward-seeking behavior under punishment, with a focus on potential sex-specific effects. Using a …

September 4, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Re: Comment Letter For The Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites New And Mahoney (Ur-23) Construction Completion Report., Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Draft Final Insufficiently Reclaimed Sites Field Sampling Plan (Fsp): Bres No. 18 – Walkerville Ballfield (Dated August 13, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Climate Change-Related Threats To Railroads: Implications For Threat, Hazard And Risk Assessment, Frances L. Edwards, Daniel C. Goodrich

Faculty Research, Scholarly, and Creative Activity

Climate change has created new challenges for railroads around the world. The rail systems operate in open environments, subjecting them to increased heat, changing locations of heavy rains, developing sea level rise and storm surge, and a longer and stronger wildfire season. This research investigates how an updated threat and hazard identification and risk assessment (THIRA) can lead to the development of climate adaptation strategies that limit damage and disruption to the railroad enterprise. The THIRA analyzes which threats are of most concern in a specific rail segment, and which climate change adaptation strategies give a beneficial return on investment.

Preconditioning With Low-Dose Radiation Improves Antitumor Immunity And Survival In Dc-Vaccinated Mice, Eric Kwon, Shelby Namen, Colin J Willoughby, Solomon Kang, Gaurav Pandey, Alexander B Kim, Carl J Deselm

2020-Current year OA Pubs

Preconditioning regimens are essential for the immunologic success of cell therapies like CAR T cells. Nevertheless, their effect on cancer vaccines is underexplored, and preconditioning regimens are generally absent from cancer vaccine clinical trials. To address this knowledge gap, we evaluated the impact of various preconditioning strategies on dendritic cell (DC) vaccine efficacy in a murine tumor model. Mice bearing syngeneic tumors received preconditioning with 2 Gy low-dose radiation therapy (LD RT; whole-body or tumor-only), cyclophosphamide, paclitaxel, LD RT plus cyclophosphamide, or no preconditioning, followed by administration of antigen-loaded DCs. Whether whole-body or tumor-directed, LD RT preconditioning significantly enhanced vaccine-induced …

Risk Of Clonal Hematopoiesis In Families Exposed To Radiation Following The Chornobyl Accident, Mitchell J Machiela, Irenaeus Chan, Kelly Bolton, Et Al.

2020-Current year OA Pubs

Radiation exposure is a well-established risk factor for leukemia. Clonal hematopoiesis (CH), the expansion of mutated hematopoietic cells, is also associated with increased leukemia risk and its frequency is higher in cancer patients following radiotherapy and chemotherapy. We investigated whether low to moderate environmental ionizing radiation determined by state-of-the-art dosimetric analysis was associated with CH in the Chornobyl Family Study (CFS). Our study conducted targeted high-depth sequencing and array genotyping to identify and characterize clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) in 882 participants from 292 CFS families. Fathers had mean bone marrow radiation doses of …

Building Multimodal Knowledge Graphs: Automation For Enterprise Integration, Ritvik Garimella, Hong Yung Yip, Revathy Venkataramanan, Amit P. Sheth

Publications

As enterprises increasingly aim to incorporate artificial intelligence into their workflows to tackle complex, multimodal tasks, the demand for intelligent, robust, and trustworthy systems is paramount. While multimodal large language models offer initial capabilities for processing diverse data streams, their dependence on embedding-based representations limit their effectiveness in delivering semantically grounded explanations and reasoning, as well as qualities essential for enterprise-grade applications. Neurosymbolic approaches provide a promising alternative by enabling traceable, context-aware decision making. However, constructing enterprise-level multimodal knowledge graphs (MMKGs) that enable neurosymbolic approaches remains largely impractical. Although prior efforts have explored MMKG construction, they fall short in addressing …

A Proven Template For Providing Streamlined, Scalable, Cost-Effective Clinical Research Opportunities In Osteopathic Medical Schools, Jacey N. Greek, Andrew Greek, Mari Hopper, Robert Arnce

Student Publications

Context: In an era in which clinical research plays a crucial role in advancing medical knowledge and contributing to the resume of medical students attempting to match into a residency, the creation of sustainable and effective research opportunities within medical education is paramount. Colleges of Osteopathic Medicine (COMs) face unique challenges in creating these opportunities in a scalable and cost-efficient manner. Without these opportunities, osteopathic medical students may find themselves at a disadvantage compared to their allopathic counterparts in residency placements and academic career paths.

Objectives: We have created a template for providing perpetual, streamlined, scalable, cost-effective clinical research at …

The Causal Pivot: A Structural Approach To Genetic Heterogeneity And Variant Discovery In Complex Diseases, Chad A Shaw, C J Williams, Taotao Tan, Daniel Illera, Nicholas Di, Joshua M Shulman, John W Belmont

Center on Aging Staff Publications

We present the Causal Pivot (CP) as a structural causal model (SCM) for analyzing genetic heterogeneity in complex diseases. The CP leverages an established causal factor or factors to detect the contribution of additional suspected causes. Specifically, polygenic risk scores (PRSs) serve as known causes, while rare variants (RVs) or RV ensembles are evaluated as candidate causes. The CP incorporates outcome-induced association by conditioning on disease status. We derive a conditional maximum-likelihood procedure for binary and quantitative traits and develop the Causal Pivot likelihood ratio test (CP-LRT) to detect causal signals. Through simulations, we demonstrate the CP-LRT’s robust power and …

Implementing A Training Resource For Large-Scale Genomic Data Analysis In The All Of Us Researcher Workbench, Jasmine Baker, Erik Stricker, Julie Coleman, Shamika Ketkar, Taotao Tan, Ashley M Butler, Laterrica Williams, Latanya Hammonds-Odie, Debra Murray, Brendan Lee, Kim C Worley, Elizabeth G Atkinson

Duncan NRI Faculty and Staff Publications

A lack of representation in genomic research and limited access to computational training create barriers for many researchers seeking to analyze large-scale genetic datasets. The All of Us Research Program provides an unprecedented opportunity to address these gaps by offering genomic data from a broad range of participants, but its impact depends on equipping researchers with the necessary skills to use it effectively. The All of Us Biomedical Researcher (BR) Scholars Program at Baylor College of Medicine aims to break down these barriers by providing early-career researchers with hands-on training in computational genomics through the All of Us Evenings with …

Experiences Of Immigrant Adults About English As A Second Language Classes With Instructors Who Do Not Speak Learners’ Languages, Gatluak Pal

Walden Dissertations and Doctoral Studies

The problem addressed in this study was the lack of research on the experiences of adult immigrant English language (EL) learners regarding their engagement in college-level English as a second language (ESL) courses with instructors who do not speak the learners’ native language. Researchers have reported that EL-learning immigrant adults are not actively engaging in their learning process. The purpose of this basic qualitative study was to investigate the experiences of EL-learning adult immigrants regarding their engagement in ESL college classes with instructors who do not speak the native language of their learners. A basic qualitative study was conducted using …

Effects Of Elementary And Secondary School Emergency Relief Grants On Math And English Language Arts Standardized Test Scores In Connecticut, Zoe Robinson

Walden Dissertations and Doctoral Studies

The problem addressed through this study was the decrease in proficiency levels in math and English Language Arts (ELA) of 3rd- to 8th-grade students on standardized tests following the COVID-19 pandemic in Connecticut (CT). The purpose of this quantitative study was to examine the difference between the mean change in math and ELA standardized test scores for Grades 3-8 for 4 years before and 4 years after the introduction of the Elementary and Secondary School Emergency Relief (ESSER) grant funding in CT, while controlling for all other funds received. The theory that supported this study was Lezotte’s school effectiveness and …

The Impact Of Communication And Job Satisfaction On Registered Nurse Turnover, Kingsley Kenechukwu Onyeama

Walden Dissertations and Doctoral Studies

Health care leaders are challenged with ongoing nursing shortages. The purpose of this quantitative, correlational study was to examine the impact of communication and job satisfaction on registered nurses’ turnover intentions. The conceptual framework integrated Maslow’s Hierarchy of Needs, Herzberg and Mausner’s Motivation-Hygiene Theory, and Social Exchange Theory. Two research questions guided the study: the relationship between communication variables and intent to leave a healthcare organization, and the relationship between job satisfaction and intent to leave. A randomized sample of 156 registered nurses in California, aged 23 to 65 and identified through the California Nurses Database, was recruited via SurveyMonkey. …

What Are The Lived Experiences Of Policing Professionals With Self-Reported Alterations To Biological Instinct Alongside Operational Demands?, Madyson Wier

Walden Dissertations and Doctoral Studies

Operational demands and training of policing professionals may be a source of conflict leading to a potential increase in risk for both the officer and the general public. Training in a law enforcement academy does not adequately prepare officers for the impacts the career may have on mental health, changes to the biological system, or societal criticism of modern-day policing. The purpose of this qualitative study was to understand how policing professionals experience changes in the autonomic nervous system with exposure to trauma in the field, and how self-reported alterations are further impacted due to operational expectations of their department. …

Dampak Jumlah Kredit Yang Dimiliki Rumah Tangga Terhadap Kekerasan Dalam Rumah Tangga (Kdrt) Pada Anak Di Indonesia, Anjar Maulitfiani, Dwini Handayani

Jurnal Kebijakan Ekonomi

This study examines the impact of intensity of household debt on domestic violence (DV) towards children in Indonesia. There is a positive relationship between the amount of household debt and the likelihood of domestic violence towards children based on literature review. This research uses a quantitative method with multinomial logistic regression analysis. The results of this study indicate that households with more than one household debt are correlated with an increased likelihood of both psychological and physical domestic violence towards children compared to the likelihood of no domestic violence, both before and after controlling variables added.

A Tale Of Two Schools: A Comparative Case Study Demonstrating Organizational Pathways To Educator Collaborations, Michael W. Valenti Ph.D., Duhita Mahatmya, Elizabeth Levine-Brown, Karen Celedonia, Tracy Sweet

Mid-Western Educational Researcher

Effective staff collaboration in schools maximizes educators’ collective capacity, improves educator and student outcomes, and facilitates school-wide improvement efforts. Yet, many school team members struggle to collaborate effectively. Previous studies have demonstrated individual and school-level factors that influence school-based collaborations. This study expands former research by comparing the varying administrative and environmental tools employed by two schools to shape relational networks and foster interpersonal capital. Specifically, this case study explores how school-level factors shape the development of school social networks and staff collaborative behavior. We use comparative case study analysis to explore how differences in individual-level and system-level factors influence …