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Spartan Daily, September 11, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 9

Nmr-Based Metabolomic Profiling For Brain Cancer Diagnosis And Treatment Guidance, Julia R Zickus, José S Enriquez, Paytience Smith, Bill T Sun, Muxin Wang, Aldo Morales, Pratip K Bhattacharya, Shivanand Pudakalakatti

Faculty, Staff and Student Publications

Nuclear magnetic resonance (NMR) spectroscopy is a routinely used analytical tool for studying chemical entities of varying molecular sizes, ranging from approximately 20 Da to ~45 kDa, and in some cases even larger. Over the past two decades, the use of NMR spectroscopy has significantly expanded to the study of metabolomics. In this medium-sized review, the application of NMR-based metabolomics in the diagnosis, therapeutic intervention, and guidance of therapy for various types of brain cancer is discussed.

Ubiquitination-Targeted Therapies Improve Bmd Ipsc Myogenic Cell Engraftment And Dystrophin Expression In Vivo, Muchen Liu, Somik Chatterjee, Jianbo Wu, Zeinab Kashaniasl, Ashok Kumar, Chunru Lin, Radbod Darabi

Faculty, Staff and Student Publications

Becker muscular dystrophy (BMD) is caused by in-frame mutations in dystrophin gene, leading to progressive muscle weakness, and cardiac and respiratory complications. Currently, there is no cure. We have recently identified the importance of poly-ubiquitination in regulating dystrophin stability through the binding of lncRNA H19 to the dystrophin C-terminal zinc-finger domain (ZNF), inhibiting TRIM63-mediated poly-ubiquitination. We also demonstrated that BMD mutations lead to conformational changes in ZNF domain, reduced lncRNA H19 binding and increased dystrophin ubiquitination. Here we used BMD iPSCs to investigate the in vitro myogenic potential of BMD myogenic cells, as well as in vitro and in vivo …

Complete Genome Sequence Of Actinomyces Oris Strain Mg-1: An Oral Commensal Critical For Dental Plaque Formation, Bibek G C, Kexin Tan, Chenggang Wu

Faculty, Staff and Student Publications

Actinomyces oris MG-1 is a key oral commensal involved in dental plaque formation. We report its complete genome sequence, generated using Illumina and Oxford Nanopore sequencing. The genome consists of a single circular chromosome of 3,042,829 bp, providing a resource for future functional studies.

Neuroengineering Approaches Assessing Structural And Functional Changes Of Motor Descending Pathways In Stroke, Jordan N Williamson, Rita Huan-Ting Peng, Joohwan Sung, Mahmood Rajabtabar Darvish, Xiaoxi Chen, Mehreen Ali, Sheng Li, Yuan Yang

Faculty, Staff and Student Publications

Stroke is a leading cause of adult disability worldwide, with approximately 101 million survivors globally. Over 60% of these individuals live with from long-term, often lifelong, movement impairments that significantly hinder their ability to perform essential daily activities and maintain independence. Post-stroke movement disabilities are highly associated with structural and functional changes in motor descending pathways, particularly the corticospinal tract and other indirect motor pathways via the brainstem. For decades, neuroengineers have been working to quantitively evaluate the post-stroke changes of motor descending pathways, aiming to establish a precision prognosis and tailoring treatments to post-stroke motor impairment. However, a clear …

Dilated Coronary Sinus Causing Left Ventricular Inflow Obstruction: Decision On Surgical Intervention, Hamood N. Al Kindi, Madan M. Maddali, Justin Tretter

Sultan Qaboos University Medical Journal

Objectives: A significantly dilated coronary sinus causing left ventricular inflow obstruction presents a challenging dilemma during surgical repair of associated anomalies. We report a 5-month-old male infant was referred to a national heart centre in Muscat, Oman, in 2023 with a persistent left superior caval vein, dilated coronary sinus, partially anomalous pulmonary venous drainage and a large atrial septal defect, resulting in left ventricular inflow obstruction and low cardiac output. The dilated coronary sinus intensified a left-to-right shunt, leading to left ventricular underfilling and early heart failure symptoms. Although surgical correction was planned, direct intervention on the coronary sinus …

Neurotransmitter Signaling In Molecular And Behavioral Immune Responses To Pathogens In C Elegans, Benson Otarigho, Alejandro Aballay

Faculty, Staff and Student Publications

Neurotransmitter signaling pathways play major roles in both molecular and behavioral defenses against pathogen invasion, shaping the ability of Caenorhabditis elegans to sense and respond to environmental challenges. Given the conservation of neurotransmitter signaling pathways, their understanding may not only provide insights into the neurobiology of C. elegans but also has broader implications for our understanding of neural-immune interactions and host defense mechanisms in higher organisms. In this review, we discussed the literature on various neurotransmitter signaling pathways, including serotonergic, dopaminergic/octopaminergic, GABAergic, and glutamatergic pathways, and how these pathways modulate molecular and behavioral immune defense against pathogens.

September 11, 2025, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Investigating Temperature Influences On Shell Growth And Microstructural Variations In Bay Scallops: Insights From Multiscale Microscopy, Benazir Khurshid, Arnaud Benchetrite, Lise Guichaoua, Nicolas Brodusch, Bryce D. Stewart, Roland Kröger, Raynald Gauvin, Martin Mallet, Réjean Tremblay, Natalie Reznikov

School of Biological and Marine Sciences

Scallops (order Pectinida) are well-known for their robust and beautiful calcitic shells that protect them from external impacts and predators. Scallops respond to environmental conditions, including water temperature, salinity, and food supply, which are reflected in the shell growth rates and patterning. The bay scallop (Argopecten irradians) is a species of high ecological and aquacultural value in North America, and its habitat may expand towards higher latitudes with inevitable global warming. To investigate the effect of water temperature on the accretion rate and the polycrystalline microstructure of the Bay scallop shell, we conducted a controlled growth experiment on juveniles, 4 …

The Colonic Crypt: Cellular Dynamics And Signaling Pathways In Homeostasis And Cancer, Anh L. Nguyen, Molly A. Lausten, Bruce M. Boman

College of Life Sciences Faculty Papers

The goal of this review is to expand our understanding of how the cellular organization of the normal colonic crypt is maintained and elucidate how this intricate architecture is disrupted during tumorigenesis. Additionally, it will focus on implications for new therapeutic strategies targeting Epithelial-Mesenchymal Transition (EMT). The colonic crypt is a highly structured epithelial unit that functions in maintaining homeostasis through a complex physiological function of diverse cell types: SCs, transit-amplifying (TA) progenitors, goblet cells, absorptive colonocytes, Paneth-like cells, M cells, tuft cells, and enteroendocrine cells. These cellular subpopulations are spatially organized and regulated by multiple crucial signaling pathways, including …

Human Toxocariasis, Susana Lopez-Alamillo, Pravallika Padyala, Megan Carey, Megan M Duffey, Jill E Weatherhead

Faculty, Staff and Students Publications

Human toxocariasis is a globally prevalent zoonotic parasitic infection caused by larvae of Toxocara species, primarily Toxocara canis and Toxocara cati. Toxocariasis is commonly transmitted to humans through the ingestion of embryonated Toxocara eggs found in contaminated soil, water, or on surfaces contaminated with animal feces. Unlike in dogs and cats, humans are not definitive hosts for Toxocara spp., and, as a result, Toxocara larvae do not complete their life cycle in humans. Instead, following accidental oral ingestion of embryonated eggs, Toxocara larvae undergo an aberrant larval migratory cycle to various organs including the lungs, liver, muscles, and central …

Assessing Reliable Change, Mcid, Treatment Response, And Remission Using The Pediatric Anxiety Rating Scale (Pars) In Youth With Anxiety Disorders, Matti Cervin, Philip C Kendall, John C Piacentini, Elizabeth A Gosch, Jeffrey J Wood, Sophie C Schneider, Alison Salloum, Boris Birmaher, Andrew G Guzick, David Mataix-Cols, Eric A Storch

Faculty, Staff and Students Publications

Youth anxiety disorders are common and heterogeneous. The Pediatric Anxiety Rating Scale (PARS) is a clinician-administered tool designed to assess overall anxiety severity, independent of specific symptoms. The thresholds on PARS for the reliable change index (RCI), the minimal clinically important difference (MCID), treatment response, and full and partial remission remain unclear. Using the Clinical Global Impression (CGI) scales and diagnostic interviews as benchmark measures, several thresholds for the 6-item PARS were estimated using data from 904 youth with anxiety disorders, of which 36 % had an autism diagnosis. Data were drawn from 9 clinical trials conducted in the United …

September 11, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Barriers And Timely Postoperative Radiation Therapy In Head And Neck Cancer, Megan T Nguyen, Emily Kistner-Griffin, Reid Demass, Bhisham S Chera, Chanita Hughes Halbert, Katherine R Sterba, Elizabeth G Hill, Brian Nussenbaum, Anthony J Alberg, Vlad C Sandulache, David J Hernandez, Ryan S Jackson, Sidharth V Puram, Russel Kahmke, Nosayaba Osazuwa-Peters, Gail Jackson, Sue S Yom, Evan M Graboyes

Faculty, Staff and Students Publications

Importance: Initiation of postoperative radiation therapy (PORT) within 6 weeks of surgery is associated with improved outcomes among patients with head and neck squamous cell carcinoma. However, the relationship of barriers to care with timely PORT is unknown.

Objective: To categorize barriers to timely PORT, evaluate the association of barriers to care with initiation of timely PORT, and describe the primary reason for delay among patients without timely PORT.

Design, setting, and participants: This prospective cohort study at a US academic medical center included adults with head and neck squamous cell carcinoma undergoing curative-intent surgery with an indication for PORT. …

Montana Kaimin, September 11, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

The Hidden Link Between Hiv And Cardiomyopathy: Unraveling Hiv's Impact On The Heart, Toluwalase Awoyemi, Oluwaremilekun Zeth Tolu-Akinnawo, Andrew Greek, Oluwakemi Adenuga, Chukwuebuka Asogwa, Isaac Ekundayo, Olamide Odusola, Oyinlola O. Fasehun, Mercy Ajayi, Onyinye Ugoala

School of Medicine Publications

This comprehensive review examines the complex relationship between human immunodeficiency virus (HIV) and cardiomyopathy, focusing on the underlying molecular mechanisms, clinical manifestations, diagnostic approaches, and treatment strategies. It highlights the significant global health burden posed by HIV and its potential to cause long-term cardiovascular complications. The review investigates the pathogenesis of HIV-associated cardiomyopathy. It elucidates the intricate cellular and molecular pathways involved, including the actions of neutrophils, monocytes, macrophages, and lymphocytes in cardiac inflammation. Key signaling pathways such as TNF-NF-κB and the caspase-1 inflammasome are detailed, as they contribute to cardiac infection and injury. The clinical manifestations of HIV-associated cardiomyopathy …

Innovative Glycerin Impregnation Of Female Livestock Genital Organs And Satisfaction Assessment For Veterinary Anatomy Education In Thailand, Paisan Tienthai, Jantima Intarapanya, Pawana Chuesiri

The Thai Journal of Veterinary Medicine

Veterinary anatomy education faces several challenges, including increasing student enrollment, regulatory restrictions on animal use, and limitations of traditional preservation methods. Formalin preservation poses health risks, while plastination is costly and lacks flexibility. The conventional and modified Elnady Techniques present a safer and more cost-effective alternative, offering soft and flexible specimens; however, the adverse features still appear, and some steps require expensive equipment. This study aims to refine these Elnady Techniques, called ‘innovative glycerin impregnation’ for preserving female reproductive organs by reducing costs and simplifying the process using basic equipment. Additionally, veterinary students' satisfaction with glycerin-preserved specimens was compared to …

Accelerations And Emg Differences Between Isocaloric High-Incline Walking And Level-Grade Jogging, Taj Krieger, Motoki Sato, Lex Gidley, Justus Ortega, Eli Lankford

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 995-1009, 2025. High-incline walking is a popular mode of exercise and often serves as an alternative to level-grade running for improving cardiovascular fitness. This study examined the muscle activation and biomechanical differences between high-incline walking (HIW) at a 20% grade and level-grade jogging (LGJ) at matched exercise intensities. Nineteen physically inactive adults (18-31 years) participated. Participants completed two isocaloric exercise trials (HIW and LGJ), each lasting ten minutes. EMG data were obtained from eight muscles: biceps femoris (BF), gluteus maximus (GM), lateral gastrocnemius (LG), tibialis anterior (TA), vastus lateralis (VL), anterior deltoid (AD), erector …

Editorial: A Step-By-Step Statistical Decision Framework For A Gender-Inclusive Approach In Sport And Exercise Science Research, James W. Navalta, Dustin W. Davis, Jafra D. Thomas, Whitley J. Stone

International Journal of Exercise Science

International Journal of Exercise Science 18(1): 1010-1029, 2025. The conflation of sex and gender in sport and exercise science research has led to gaps in representation and understanding of gender-inclusive outcomes. This invited editorial presents a framework to guide researchers in conducting statistical analyses that account for multiple gender identities beyond the traditional binary classification. The invited editorial guides deliberation on whether to test for sex or gender differences in sport or exercise science research. It prompts investigators to answer the question, “Is there a valid, literature-supported rationale for investigating sex or gender differences?” If “yes”, we propose approaches that …

Global Nursing Education Through Simulation Technology: Enhancing Mass Casualty Training, Matt Anderson, Adrianna Lorraine Watson, Jeanette Drake, Sonrdra Heaston, Chynna Hartle, Lauralee Preece

International Nursing Research Congress (INRC)

Background: Nursing education is a global requirement, with many institutions worldwide struggling to find adequate space, time, personnel, and finances to invest in high-quality educational modalities for disaster preparedness and interdisciplinary communication or teamwork. This modality was designed with the global implications of a scalable approach to high-quality education while anticipating financial and logistical challenges.

Purpose: to assess the self-efficacy and experiences of undergraduate student nurses and EMTs participating in a mass casualty incident simulation (MCIS).

Methods: This study was designed as a mixed-methods study in which proportional odds logistic regression was paired with thematic analysis to present a complete …

Mitigating Racism In Nursing Using The Socio-Ecological Model, Kechi Iheduru-Anderson

International Nursing Research Congress (INRC)

Background: In 2021, the CDC identified racism as a major public health threat, highlighting its impact on social and economic determinants of health, such as education, housing, and employment, which in turn affect health outcomes (CDC, 2021; Waite et al., 2020). The nursing profession is not exempt from these effects; a 2021 survey of nurses revealed prevalent racism within nursing, influencing education, practice, and patient care (National Commission to Address Racism in Nursing, 2021). A comprehensive, multi-level approach within nursing is essential to address this issue.

Purpose: This study employs the socio-ecological model (SEM) to analyze racism in nursing and …

Interdisciplinary Simulation With Psychiatric Nurse Practitioner And Midwifery Students, Marissa Decesaris Siegel, Abigail Howe-Heyman, Joseph Schatz

International Nursing Research Congress (INRC)

Background: Mental health is the leading cause of pregnancy-related mortality in the United States.¹ Both psychiatric and midwifery providers often lack confidence in managing mental health disorders in perinatal patients and may also lack experience in interprofessional collaboration, a key domain of the American Association of Colleges of Nursing’s Essentials.² We are not aware of any existing programs that use interprofessional education to address perinatal mental health.

Purpose: The purpose of this project was to assess the feasibility of a post-partum depression simulation with psychiatric/mental health nurse practitioner (PMHNP), women's health/gender-related health nurse practitioner (WHGRNP), and nurse- midwifery …

Trust, Blame, And The Words Nurses Use, Jane K. Dickinson, Susan J. Guzman, Jennalee Wooldridge

International Nursing Research Congress (INRC)

The purpose of this study was to quantify emotional responses, including trust and blame, of people with diabetes, when exposed to problem words.
People with diabetes experience words that are judgmental and based on blame.¹ Language guidance papers have been developed in multiple countries, because negative messages can be harmful to people with diabetes.² A recent integrative review synthesized studies on communication and diabetes outcomes and concluded that negative messages can lead to diabetes distress, decreased health behaviors, and poor health outcomes. On the other hand, positive or supportive messages can lead to positive health behaviors.³
Trust …

A Model Of The Determinants Of Maternal Mortality In Indigenous Women, Jennifer L. Heck, Judy Goforth Parker, Kathryn M. L. Konrad, Ingrid Svenson, Annika Jennings

International Nursing Research Congress (INRC)

Despite increasing attention to the well-documented maternal health crisis in the U.S., stark disparities persist between groups of women. In December 2021, Indigenous mothers experienced 118.7 maternal deaths per 100,000 live births, whereas their White counterparts had 26.6 [1]. Maternal mortality is a multifaceted, complex issue that complicates the health and wellbeing of Indigenous women, yet the root causes of this disparity are not well-described. We need a deeper understanding of the determinants of health (social, structural, biological, political) that contribute to Indigenous maternal mortality. Indeed, the existing literature lacks adequate theoretical understanding to address this phenomenon. Therefore, the purpose …

Ehric Model For Non-Fatal Strangulation: A Novel Risk Assessment Framework, Chelsea Knutson, Patricia Ann Carter

International Nursing Research Congress (INRC)

Abstract Text: Background: Non-fatal strangulation (NFS) is a critical yet often overlooked form of violence, frequently occurring within sexual assault and domestic violence contexts. Despite its severity and prevalence, significant gaps remain in understanding NFS risk factors, hindering effective prevention and intervention strategies.

Purpose: This study aims to synthesize current literature on NFS risk factors and develop a novel conceptual model to aid in identifying high-risk individuals, informing clinical practice and policy-making in nursing and healthcare.

Methods: A comprehensive literature review was conducted using MEDLINE and CINAHL databases, with the keyword 'non-fatal strangulation', up to August 2024. The search was …

Translational Science Of Blended Tube Feedings, Amy Spurlock, Noah Thomas

International Nursing Research Congress (INRC)

The purpose of this research synthesis is to summarize translational science on Blended Tube Feeding (BTF) and the commentary that led to further research in the field.

Since 2013, nine papers have been published by a team on BTF. These papers utilized a variety of research methods to investigate the safety, efficacy, and patient outcomes of BTF compared to commercial formulas (CF). A case study explored the clinical improvement of a child post-transition to BTF, revealing reduced gastrointestinal (GI) symptoms and increased oral intake¹. Survey research was employed with Registered Dietitians and caregivers to assess attitudes, experiences, and …

Building Grit And Understanding Drivers Of Dropout Intentions Among Nursing Students, Marianne Biangone, Daniel Terry, Blake Peck, Jeong-Ah Kim, Linda Jones

International Nursing Research Congress (INRC)

Introduction: Defined as a combination of passion, perseverance, and long-term commitment, grit is the sustained effort to achieve difficult goals over time.^1,2 Nursing students have grit, which continues to develop as they enter the profession. However, nearly 20% of students do not complete their studies, despite academic and pastoral support.³ Interventions designed to develop mindsets, such as the six-week ‘Grow your Grit’ program⁴, better equip students for the rigors of academia. However, limited insights regarding the granular issues that drive dropping out exist.⁵

Purpose: To understand challenges that lead to increased dropout intentions among first-year …

Representing A Globally Diverse Profession: Implementing A Holistic Interview Process For Applicants, Courtney Chovanetz, Laura Opton, Irene Salinas, Kara Moellenberg

International Nursing Research Congress (INRC)

As the national nursing shortage rises across the United States, educators continue to focus on providing quality education and producing competent bedside nurses. However, there remains a lack of diversity in the nursing profession (Breland, 2020). Ensuring a student body is representative of various experiences and personal attributes creates a nursing workforce that more closely reflects the population and is prepared to successfully lead and impact health outcomes equity (Wagner et al., 2020). Implementing holistic interview processes will allow for the evaluation of life experiences and core values demonstrating a more accurate representation of how individuals will practice as professionals …

Unfolding Narratives: An Arts Health Project To Promote Empathy And Compassion In Nursing Education, Diana Catherine Jefferies, Stephen Mcnally, Paul Glew, Annette Stunden, Aileen Pamonag Lane, Lucie Michelle Ramjan

International Nursing Research Congress (INRC)

Empathy and compassion are core attributes when nurses are developing therapeutic relationships with vulnerable people in their care (Levett-Jones et al., 2019). The Unfolding Narratives uses a co-design arts health approach to create authentic, engaging and evidence based short films. The purpose of the films is to encourage pre-registration nursing students to reflect on their communication skills when caring for people who are living with mental ill health, dementia or are distressed by their life circumstances. Using a sliding door approach the films show how health outcomes are improved by empathetic and compassionate communication. They also demonstrate that without these …

Empowering Nurses Through Scope Advancement: Strategies For Professional Growth, Venise Bryan, Kristin Petrovic, Kelly Decoste

International Nursing Research Congress (INRC)

Nurses globally work within various scopes of practice, from entry-level to advanced roles, and play a vital role in meeting the health needs of individuals and communities across diverse healthcare settings. Nurses can further their education, to advance their scope, such as diploma-prepared Licensed/Registered Practical Nurses (LPNs/RPNs) completing their Bachelor of Nursing (BN) to become Registered Nurses (RN). In Canada, select BN programs use innovative pedagogies to specifically bridge curriculum that recognizes LPN/RPN experience (Chachula et al., 2020). LPN/RPN to BN learners bring rich clinical experience and diversity as they engage in career advancement and professional development (Almost, 2021).

A …