Digital Commons Network^™

From Peak To Plunge: A Multi-Database Analysis Of State-Level Disparities In Hydromorphone Use In The Us, Krisha S. Patel, Leana J. Pande, Kenneth L. Mccall, Brian J. Piper

Pharmacy Faculty Scholarship

Background: Hydromorphone is a semi-synthetic opioid agonist and a hydrogenated ketone of morphine. This study examined hydromorphone use in the United States (US) using three databases. Methods: The distribution of hydromorphone in the US (in grams) was provided by the US Drug Enforcement Administration’s Automated Reports and Consolidated Orders System (ARCOS) by state, zip code, and business type (pharmacies, hospitals, providers, etc.). Hydromorphone prescription claims were also examined using the Medicaid and Medicare Part D programs from 2010 to 2023. Results: Hydromorphone increased by +30.6% by 2013, followed by a decrease of −55.9% by 2023 in ARCOS. Medicaid prescriptions increased …

Early Outcomes Of Y-Incision Vs. Conventional Techniques For Aortic Root Dilatation, Ahmed Shafeek Ali, Mahmoud Maher Abdou Ibrahim, Haitham Alshahat Ramadan

Journal of Medicine in Scientific Research

Background The y-incision method for expanding the aortic annulus has proven its effectiveness and safety in the short term. We aim to compare the early results of this method with those of the conventional annular dilatation techniques. Methods From March 2022 to April 2024, Eighty consecutive patients at the National Heart Institute in Cairo, Egypt, received aortic valve replacement (AVR) combined with aortic root dilatation (ARD) Utilizing either conventional annular dilatation techniques (group 1, n=40), including Manouguian [12.5% (10/80)], Nicks [35% (28/80)], and others [2.5% (2/80)], or method of Y-incision (group 2, n=40) [ 50% (40/80)]. Preoperative, intraoperative, and early …

Early Outcomes Of Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention For Patients With Intermediate Syntax Ii Score, Ahmed A Faragalla, Ahmed M Elshiemy, Ahmed K. Hassan, Sherif M. Elboghdady, Wael S. Nekhila

Journal of Medicine in Scientific Research

Background Navigating the treatment landscape for those whose SYNTAX II scores reside in the transitional band of 23 to 32 (the intermediate score zone) continues to present a formidable clinical dilemma, with the therapeutic arsenal offering divergent paths: the surgical undertaking of coronary artery bypass grafting (CABG), the catheter-based strategy of percutaneous coronary intervention (PCI), or the non-interventional realm of medical therapy. Aim To evaluate the frequency of major adverse cardiac or cerebrovascular events (MACCE) during the in-hospital period following re-vascularization procedures in participants graded as intermediate SYNTAX II scores. Methods A retrospective study was conducted at the National Heart …

Acute Kidney Injury After Open Heart Surgery: The Diagnostic And Predictive Value Of The New Biomarkers, Ahmed A Faragalla, Ahmed M Elshiemy, Sherif A. Elhendawy

Journal of Medicine in Scientific Research

Background Post-operative acute kidney injury (AKI) following cardiac surgery represents a significant clinical challenge, associated with heightened mortality and an increased propensity for chronic kidney disease. Ischemia-reperfusion injury, a primary pathophysiological mechanism, induces renal tubular damage, releasing biomarkers such as Neutrophil gelatinase-associated lipocalin (NGAL) and hemojuvelin (HJV) into the urine. The quantification of these urinary biomarkers offers a means for early AKI detection and risk stratification, with the potential to improve patient prognosis. Aim This investigation tested new urinary biomarkers to detect AKI within the first 24 hours, to enable prompt intervention and enhance patient care. Patients and Method Sixty-three …

Intraoperative Endoscopic Finding Of The Paranasal Sinus Mucoceles, Anwar Moawad Elbatawy, Essam Fathy Mohamed, Mohammad Mostafa Gaballah

Journal of Medicine in Scientific Research

Background Mucocele of the nose and paranasal sinuses are a slowly benign expansion that may cause compression of the surrounding important structures such as the orbit or the brain in 44.9% of cases. Mucopyocele is a rare presentation (especially maxillary mucopyocele) resulting from a secondary bacterial infection. CT scan of the paranasal sinus is efficient in identifying and localizing the affected sinus and its bony extension also helps to plan the endonasal endoscopic surgery. Material and methods This is a retrospective study, we have documented 9 cases with a history of mucocele, or mucopyocele. 2 cases are excluded. One of …

Temperamental Traits For Infants And Toddlers With Rickets, Rabab Salah Eldin Mohamed

Journal of Medicine in Scientific Research

Background Rickets is a deficiency in the mineralization of developing bone. Infant temperament comprises a collection of qualities that define individual behavior. The objective of this work was to determine if there were variations in temperamental qualities between ricketic and normal babies and toddlers, and whether such differences varied by sex. Methods This cross-sectional work had been conducted on 100 children aged from 6 to 24 months both sexes, with rickets (Group 1), and 100 normal sex- and age-matched children as a control group (Group 2). All patients underwent evaluation of temperamental traits. The assessment of psychological aspects for both …

Combined Effect Of Letrozole And Dydrogesterone Versus Dydrogesterone Alone For Relieving Pain In Patients With Endometriosis, Mohamed M.H. Elwakeel, Mohamed A.T. Elsharawy, Abdelghaffar S. Dawod, Dina G. Elkhouly

Journal of Medicine in Scientific Research

Background Endometriosis is a medical condition in women caused by the growth of active endometrial tissue outside the uterine cavity. It predominantly affects women of reproductive age and typically manifests as dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. It negatively impacts psychological well-being and health-related quality of life. Aim This study aims to compare the effect of the combination of letrozole and dydrogesterone versus the effect of dydrogesterone alone in pain-associated endometriosis Patients & Methods This randomized controlled study was conducted on 88 women with endometriosisassociated pain in the gynecologic outpatient clinic at Tanta University Hospitals, from October 2023 to …

Study Of Awareness, Knowledge, Attitude And Practice Of Pediatric Healthcare Practitioners Towards Wilson Disease., Hanaa Ahmed Elaraby, Magdy Anwar Saber, Sally Waheed Elkhadry, Salwa Gamal Attia, Gihan Ahmed Sobhy

Journal of Medicine in Scientific Research

Background; Wilson disease (WD) is a rare genetic disease that occurs secondary to an excess of copper building up in our body, especially in the liver and brain. Diagnosis of WD is challenging. Since it is a curable illness, raising awareness about it among medical professionals is essential. Aim of the work; to assess the awareness, knowledge, attitude and practice of pediatric practitioners towards WD providing useful alerts about this disease and augmenting their knowledge. Participants and Methods ; Five hundred and one (501) pediatric practitioners with varying academic degrees from several Egyptian governmental hospitals participated in this cross-sectional study …

A Recent Insight On Prevalence Of Atopic Diseases In Children With Type 1 Diabetes, Randa Mohamed Darwish, Ayat Ibrahim Ghanem

Journal of Medicine in Scientific Research

Background Type 1 diabetes mellitus (T1DM) and atopic diseases are both prevalent immunemediated conditions in children. Although traditionally viewed as immunologically opposing disorders—T1DM being Th1-mediated and atopy Th2-mediated—recent studies suggest possible overlap in genetic susceptibility and environmental triggers. This study aimed to evaluate the prevalence and association of various atopic conditions in pediatric T1DM patients. Aim of the study To investigate the prevalence of atopic diseases—including atopic dermatitis, allergic rhinitis, allergic conjunctivitis, bronchial asthma, food allergy, and anaphylaxis—among children with T1DM compared to healthy age- and sex-matched controls, and to analyze contributing risk factors. Methods A retrospective cohort study was …

Imaging Characterization Of Central Nervous System Affection In Hematological Malignancies Patients, Eman Nasr Said, Samia Yehia Abdelrazek Heikal, Ayda A. Youssef, Marwa Romeih, Mary Rabea Mahrous

Journal of Medicine in Scientific Research

Background Central nervous system (CNS) complications in patients with hematological malignancies pose significant diagnostic and therapeutic challenges. Magnetic resonance imaging (MRI), with its various sequences, plays a pivotal role in early diagnosis, characterization, and differentiation of these conditions to guide management and improve outcomes. Objective This research aimed to assess the diagnostic performance and utility of different MRI sequences (conventional, diffusion-weighted imaging (DWI), and apparent diffusion coefficient (ADC) mapping) in detecting and differentiating CNS complications in patients with hematological malignancies presenting with neurological manifestations. Methods A retrospective cohort of 130 patients (age range 2–81 years; 60% male and 40% female) …

Climate Change Projections Through Optimized Machine Learning And Deep Learning Models: A Comprehensive Analysis, Hala H. Youssef, Salma S. Mohammed, Hanan M. Amer, Abeer T. Khalil

Mansoura Engineering Journal

One major worldwide issue that has far-reaching effects on environmental stability and the avoidance of natural disasters is climate change. Developing efficient mitigating strategies depends on precise climate change forecasts. To predict important climate change indicators, including temperature fluctuations, greenhouse gas (CO2, N2O, CH4, and SF6) emissions, population dynamics, sea level changes, Arctic Sea ice extent, and Antarctica mass, this study evaluated the predictive capabilities of several Machine Learning (ML) and Deep Learning (DL) techniques. The set of machine learning algorithms includes Multiple Linear Regression (MLR), K-Nearest Neighbors (KNN), Support Vector Machines (SVMs), Artificial Neural Networks (ANN), Random Forest (RF), …

Global Goals, Local Impact: Advancing Nursing Education Through Sdg Integration, Elise H. Peterson, Melissa Robertson

Global Advocacy

Undergraduate nursing students are future healthcare leaders who not only provide direct patient care but also influence community and global health outcomes. The United Nations Sustainable Development Goals (SDGs) provide a comprehensive framework to address pressing health and social challenges, including reducing inequalities, promoting well-being, ensuring access to quality education, and combating climate-related health threats. Integrating SDGs into nursing education equips students with the knowledge, skills, and advocacy mindset to address these challenges at local, national, and global levels.

Nurses are pivotal in achieving SDG-related outcomes such as health equity, disease prevention, and sustainable community interventions. Currently, nursing curricula often …

Nursing The Future: Advocating For Equitable And Ethical Use Of Robots In Nursing Practice, Aminat A. Adeyemo, Nancy S. Ferrell Jones, Hon Lon Tam

Global Advocacy

Background: Health systems face rising pressures from ageing populations, complex care needs, workforce burnout, and persistent nursing shortages. Robotics and artificial intelligence (AI) are emerging as potential supports; however, without clear policies, preparation, and nurse involvement, deployment risks being unsafe, inequitable, and poorly aligned with real-world care.

Aim: To advocate for the responsible, equitable, and ethical integration of robots in nursing practice by aligning action across policy, education, and research, and by situating this agenda within the UN Sustainable Development Goals (SDGs 3, 4, 8, 9, and 10).

Approach/Actions: Our approach is to align policy, education, research, and partnerships to …

Reintegration Experiences Of Male Victims Of Human Trafficking, Thomas Brooks

Walden Dissertations and Doctoral Studies

Human trafficking continues to be a world-wide problem, despite attempts to mitigate it. Many human trafficking victims are saved each year, but many more do not make it out. When rescued, the victims of human trafficking need to be reintegrated back into society. Research on human trafficking survivors is mostly focused on female victims; there is little research focused on male victims. Due to this, the purpose of this research was to explore the experiences of men who have been through the reintegration process as children in America after they have been rescued from human trafficking. A phenomenological approach was …

Polarization, Performance, Responsiveness, And Trust In Malawian Executive, Legislative, And Judicial Institutions, Rodgers Brenner Chawani

Walden Dissertations and Doctoral Studies

Political trust matters for good governance and democracy. Although Malawi's constitution affirms trust as a key component of authority, Afrobarometer surveys have revealed broad declines, hindering democratic consolidation and the achievement of the long-term Vision 2063 development goals. Prior researchers studying the country have fixated on qualitative analyses and overlooked affective polarization and differentiation across government branches. The purpose of this cross-sectional quantitative study was to examine the predictive relationship between perceived government performance, responsiveness, corruption, affective polarization, democratic satisfaction, and trust in the Malawi president, parliament, and judiciary, using generalized linear models to apply Easton's political support theory to …

The Daily Gamecock: October 2025, University Of South Carolina, Office Of Student Media

2025

No abstract provided.

The Academic, Psychological, And Physical Impact Of Motor Skills Difficulties On College Students: A Scoping Review, David Gaul Phd, Suzanne Mccarthy Wolf

Articles

Purpose of Review

This scoping review examines the extent and quality of research literature to determine the impact of motor skills difficulties on college or university students. It assesses the adequacy of current institutional supports and identifies opportunities for more inclusive educational practices.

Recent Findings

Four databases (PubMed, SCOPUS, PsycINFO, and Web of Science) were searched for English-language studies published since 1970. Eighteen studies met inclusion criteria: 12 empirical, 4 descriptive, and 2 program evaluations. Six papers from the UK addressed support, social isolation, and academic confidence; six Israeli studies focused on handwriting, dysgraphia, and accommodations; three US studies examined …

The Rider (2025-10-13), Daniela Martinez Salazar

The Rider Archives

Vol. 11, No. 7

Trust-Based Adjustment Of Measurement Discrepancies In Distribution Networks, Zhiwei Huang, Yachen Tang, Chee-Wooi Ten, Guangyi Liu

Michigan Tech Publications

This paper addresses security challenges in modern electricity distribution systems, where supervisory control and data acquisition (SCADA) and advanced metering infrastructure (AMI) networks are increasingly exposed to cyber threats and fraudulent activities, leading to metering discrepancies. As smart grids become more interconnected, identifying compromised meters and devices at scale requires a robust inference framework. While alarm systems provide real-time detection of anomalies such as abrupt energy consumption changes, data losses, and security breaches, the lack of seamless integration between SCADA and AMI alarm data limits their effectiveness. To enhance grid security and resilience, this paper presents a data-driven approach for …

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.

Prompt Engineering For Genai In Cybersecurity Incident Response: A Multi-Platform Evaluation Based On Nice Pr-Ir-001, Yuanyuan Liu

Journal of Cybersecurity Education, Research and Practice

This study explores the application of prompt engineering in cybersecurity education, mainly by evaluating the performance of different generative artificial intelligence (GenAI) platforms when performing tasks consistent with the NICE framework role pr-ir-001 - Network Defense Incident Responder. The study employed structured prompts designed for a medical technology environment compliant with HIPAA and NIST SP 800-53, while the tasks of the three GenAI models (GPT-4, Gemini, and DeepSeek) were to generate event response scenarios. Their outputs will be evaluated from four aspects: accuracy, relevance, clarity and completeness.

The results show that the three models differ in depth and consistency, but …

October 2025, Pacific Alumni Association

Alumni News & Events

No abstract provided.

Strategies That Clinical Research Site Managers Use To Minimize Employee Turnover, Christina Holston

Walden Dissertations and Doctoral Studies

High turnover rates among clinical research staff present a business problem that reduces continuity, quality, and cost-effectiveness of clinical trials. This problem is important to clinical research managers because employee stability is essential for participant retention, regulatory compliance, and operational success. Grounded in the job embeddedness and transformational leadership theories, the purpose of this qualitative pragmatic inquiry was to identify and explore the effective strategies that some clinical research site managers use to reduce employee turnover in the southeastern United States. Data were collected through semistructured interviews with six clinical research leaders and triangulated with publicly available documents. Using Yin’s …

Week Of October 13, 2025, Student Life

College, School and Department Newsletters, Magazines, and Journals

Your weekly hub for events, resources and updates.

Ud In The News Oct. 4-10, University Of Dayton

News Releases

Local and regional media featured UD's "dream school status," a gift to bolster human rights studies, the Flyer Pitch competition, a partnership to improve mental health services for college students, lung cancer research and development at onMain.

The Cardioprotective Effects Of Adiponectin In Diabetes., Tara Kazemi, Yuanjie Mao, Tina Zhang

Ambulatory and Primary Care Articles

PURPOSE OF REVIEW: Adiponectin, a hormone secreted by adipocytes, plays a crucial role in maintaining metabolic balance and supporting cardiovascular health. Although it is known for its protective effects, such as improving insulin sensitivity, reducing inflammation, and maintaining endothelial function, there are paradoxical associations between high adiponectin levels and increased cardiovascular mortality-referred to as the "adiponectin paradox"-which complicates its clinical interpretation. This review explores the cardioprotective effects of adiponectin in both type 1 and type 2 diabetes, focusing on its potential to regulate glucose metabolism and prevent cardiovascular complications.

RECENT FINDINGS: By reviewing key studies, the article evaluates adiponectin's diverse …

An Integrated Pcb-Based Heating And Auto-Ranging Platform For Volatile Organic Compound (Voc) Detection Using Carbon Nanotube Based Sensors, Thomas Kalach

USF Tampa Graduate Theses and Dissertations

This thesis presents the development, characterization, and integration of a novel low-cost, high-dynamic-range sensor platform for the detection of volatile organic compounds (VOCs), leveraging the unique electrical properties of carbon nanotube (CNT) thin films. The platform introduces a fully integrated auto-ranging analog front-end circuit capable of real-time resistance measurement spanning over eight orders of magnitude ranging from tens of ohms to hundreds of megaohms, without compromising signal resolution or precision. This was achieved through a digitally controlled, multi-path feedback architecture and controllable current source.

To further enhance sensor performance, the system incorporates a copper trace heater beneath the sensor array, …

Garnet & Black Fall 2025, University Of South Carolina, Office Of Student Media

Garnet & Black Magazine

No abstract provided.

Debtor's Memo Of Law On Charitable Immunity

Catholic Dioceses in Bankruptcy

No abstract provided.

Organism-Specific Sequence Motifs Link Ribosomal Rnas To Brain Disorders, Isidore Rigoutsos, Stepan Nersisyan, Eric Londin, Iliza Nazeraj, Bonnie Dong, Anastasios Vourekas, Phillipe Loher

Computational Medicine Center Faculty Papers

We report that in humans, mice, fruit flies, and worms, the ribosomal RNAs and the transcribed spacers of 45S are densely packed with organism-specific sequence motifs that are primarily shared with nervous system genes. The human ribosomal RNAs and 45S spacers contain 1,723 such motifs. Specific combinations of these motifs are predominantly found in 3,430 human nervous system genes, of which 1,046 are genes associated with brain disorders, including autism spectrum disorder and schizophrenia. The sequences of the 1,723 motifs and their locations in the introns and exons of nervous system genes are unique to primates. Experimental evidence indicates that …