Digital Commons Network^™

Optimizing Perioperative Antibiotic Prophylaxis: A Prospective Cohort Study On Cefazolin Utilization In Surgical Patients With Penicillin Allergy Labels, Cassius Mensah, Anvinh Nguyen, Jenny Pennycuff, Israa Shwaiki, Belle Parizot, Gary Zhang, Xiaofan Huang, Suman Rajagopalan

Faculty, Staff and Students Publications

Background: Penicillin allergy labels frequently lead to second-line antibiotics for surgical prophylaxis, due to concerns for cross-reactivity. This has led to increased patient morbidity, prolonged hospitalization, and increased healthcare costs. The most common perioperative cephalosporin, cefazolin, has unique R groups, the main antigenic portion of penicillin, which makes it safe to use in type 1 hypersensitivity penicillin allergy. We evaluated the effect of education on the incidence of the following: cefazolin usage in penicillin allergy labelled patients, allergic reactions, and surgical site infections.

Methods: As a prospective study with historical controls, perioperative clinicians were educated on the natural history of …

Targeting Tet3 Suppresses Group 3 Medulloblastoma Stemness And Progression Via Impairing Hypomethylation Of Otx2 Super-Enhancer, Xuan Chen, Ziwei Wang, Yan Song, Yu Su, Yahui Zhao, Jiankang Li, Wei Wang, Jiao Zhang, Craig Daniels, Xiaochong Wu, Olivier Saulnier, Yanan Wang, Fei Liu, Kaiwen Deng, Dongming Han, Zijia Liu, Meiyu Li, Liam D Hendrikse, Alexandra Rasnitsyn, Evan Y Wang, Dongyang Wang, Zhaoyang Feng, Yanong Li, Zitong Zhao, Hongyu Yuan, Youliang Sun, Yifei Jiang, Yanfeng Shi, Tao Yang, Xueling Qi, Yong Hou, Chunde Li, Yong-Qiang Liu, Yu Tian, Shuaicheng Li, Xiaoguang Qiu, Michael D Taylor, Guo Liang Li, Tao Jiang, Hailong Liu

Faculty, Staff and Students Publications

Medulloblastoma (MB), particularly Group_3 (G3-MB), remains the most aggressive subgroup due to strong stemness and therapeutic resistance. Through genome-wide DNA methylation and transcriptomic analysis of human MB samples, we identify enhancer hypomethylation as a key feature sustaining G3-MB stemness and tumor progression. Notably, hypomethylation of the Otx2 super-enhancer (SE) is a prognostic marker and potential therapeutic target for G3-MB patients. We demonstrate that disrupting Otx2 SE activity effectively reduces tumor growth in vivo, highlighting its critical role in G3-MB maintenance. TET3, recruited by OTX2, demethylates the Otx2 SE, promoting chromatin opening and sustaining tumor proliferation and stemness. To translate these …

Single Compost Application Benefits For Organic Dryland Wheat Production, Shikha Sharma, Matt Yost, Earl Creech, Jennifer R. Reeve, Astrid R. Jacobson, Idowu Ademola Atoloye

All Current Publications

This research highlights the long-term value of compost in dryland wheat systems, where water scarcity and declining soil fertility limit productivity. A single, high-rate compost application (22 tons per acre) can improve soil moisture content, organic carbon content, aggregate stability, and microbial activity. All these benefits contributed to higher and more stable wheat yields, even more than two decades after application. These changes help to make the compost-treated wheat more resilient during dry years. While composting incurs a high upfront cost, its long-term benefits can significantly reduce the need for repeated fertilizer or soil amendments, offering cost and labor savings …

Netherton Syndrome: A Systematic Review Of The Challenges Of Diagnosis And Treatment, Maximus S. Reese, Ryan Nguyen, Noor Chughtai, Philip J. Haynos, Salma Alkhatib, Shantanu Amin, Ethan Speer, Jared Nichols

Student Publications

Netherton syndrome is an autosomal recessive genodermatosis caused by biallelic mutations in the SPINK5 gene, a gene that codes for lymphoepithelial Kazal-type-related inhibitor 1 (LEKT1) protein. This disorder is characterized by erythroderma, ichthyosis, hair shaft abnormalities, and immune dysregulation. While there is increasing research and recognition of Netherton syndrome, much remains unknown, with limited knowledge of the history, manifestations, and responses to therapies. The purpose of this study was to review case reports of Netherton’s to draw conclusions from patient demographics, symptoms, treatment, and outcomes. A systematic review of 30 case reports and clinical studies on Netherton syndrome was conducted, …

Readability Analysis Of Aaos And Assh Shoulder And Elbow Patient Education Online Content: A 9-Year Follow-Up Study, Connor Parry, Teresa Veselack, Matthew Doscher, Bryan G. Beutel

Student Publications

Given the progressive spread of medical misinformation, access to understandable educational content from trusted sources has become increasingly more crucial for patients. Online patient education materials, particularly from specialty organizations, have been criticized for being too complex for the average reader. It is advised that this information be at or below the 6^th-grade reading level. This study is a 9-year follow-up to an analysis conducted in 2013 which evaluated the overall readability of educational articles from the American Academy of Orthopaedic Surgeons (AAOS) and American Society for Surgery of the Hand (ASSH) websites related to shoulder and elbow …

The Impact Of Infrastructure Construction And Remodeling Of Cities On Its People' Quality Of Life Miraj District-(Madi-Cairo) As A Geological Heritage Area, Ahmed M.E. Hammad

Mansoura Engineering Journal

Rapid urbanization is increasing globally, the urbanization rate expected to rise to more than 66% by 2050. (According to UN estimates) the increasing rates of urbanization in the world means adding 2.5 billion people to the urban population within a short period. Which necessitates increasing the traffic axes and the rest of the networks in terms of lengths and widths within the existing cities, and with the presence of the population during these works - despite their inevitability - the quality of their urban life is affected socially, naturally and economically. the research monitors these effects and the extent of …

The Role Of Religion In Ensuring National Security In Kazakhstan, Nurzhan Arystanbekuly Tursin Nur, Mukhan Issakhan, Shamshadin Kerim, Kovalev Dmitriy, Kalimash Begalinova

Occasional Papers on Religion in Eastern Europe

This article explores the foundations of state policy aimed at ensuring religious stability in Kazakhstan. It analyzes the scientific basis of religious studies, principles of tolerance toward the country’s traditional religions, and the role of religion in maintaining national security. The methodology, goals, and objectives of the study are shaped by the interdisciplinary nature of the subject. The research examines state and interfaith relations, the development of freedom of religion, its integration into domestic and international law, and ways of resolving legal contradictions, traditions, and stereotypes. The theoretical framework relies on the works of domestic and foreign scholars devoted to …

Adventism In The Ukrainian Ssr During The Post-War Period (1946–1952): Structure, Activities, And Relations With The Authorities (A Case Study Of Vinnytsia Region)., Anatoliy A. Voynarovskiy Skiy

Occasional Papers on Religion in Eastern Europe

The article contributes to the study of Adventism as a Protestant movement and examines its structure, activities, and interactions with Soviet authorities in the Ukrainian SSR during the post-war period (1946–1952). Particular attention is paid to the organizational characteristics and functioning of the Seventh-day Adventist Church (hereinafter SDA), which, among Ukrainian SSR regions, had the largest number of adherents in Vinnytsia region. In the present-day context of Ukraine’s fight for sovereignty, formation of the national church, and protection of religious freedoms for all citizens, particular attention should be paid to understanding the role of religious institutions in the development of …

Religious Communication In Ukraine's Media Space As Factor In The Formation Of Confessional Identity, Oleh Sokolovskyi, Dmytro Garaschuk

Occasional Papers on Religion in Eastern Europe

This article presents a comprehensive study within religious studies of religious periodicals in Ukraine from the early 1990s to the present. It attempts to analyze the dynamics of the emergence and transformation of printed religious mass media in the context of the democratization of social life, changes in the information environment, and the development of civil society. It is noted that religious periodicals occupy a special place within the media landscape, since they perform not only the function of conveying information but also tasks of catechesis, spiritual-educational ministry, the formation of value orientations, and the preservation of cultural-historical heritage.

The …

Orthodoxy, Culture And Language: Alaska In Russia’S Religious Diplomacy Of The 21st Century, Oleksandr Lukyanenko

Occasional Papers on Religion in Eastern Europe

The article is devoted to the analysis of the religious factor of the Russian foreign diplomacy in the light of Vladimir Putin’s high-profile visit to Alaska n August 15, 2025. The paper studies a special place of Alaska in the historical imagination of Russian political and church discourse. The status of this particular territory in Russian state worldview – the former “Russian America” – is indicative: it refers to the idea of an unfinished imperial legacy. The research doesn’t touch a main event that included a meeting with US President Donald Trump but an off-schedule meeting with Archbishop Alexei (Trader) …

Sex, The Body, And Learning Gender: Demons In The World Of The Five Gods, Erin E. Mcbrien

Mythopoeic Society Seminar Proceedings

“Sex, the Body, and Learning Gender” analyzes the relationship between the physical body, sexual orientation, and gender as characterized within Lois McMaster Bujold’s World of the Five Gods series, with a particular emphasis on her Penric and Desdemona novellas. Using the framework of Bussey and Bandura’s social learning theory, and a close reading of Bujold’s text, this paper explores how the demonic characters within this series are an example of gender as a learned concept rather than a biological imperative. This is further developed by examining how the demonic characters both imprint on and contrast against the more societally-bound sorcerers …

Upper-Body Post-Activation Performance Enhancement In Mma Athletes: Load-Dependent Effects Across Multiple Explosive Tasks, Jan Strawiński, Dariusz T. Skalski, Magdalena Prończuk, Kinga Łosińska, Ewelina Lulińska, Miłosz Drozd, Maciej Kostrzewa, Adam Maszczyk, Robert K. Roczniok

Baltic Journal of Health and Physical Activity

Background: Post-activation performance enhancement (PAPE) has become a recognized method for acutely improving explosive output, particularly relevant to upper-body performance in combat sports. Objective: This study aimed to evaluate the effects of bench press conditioning activities (CAs) at different intensities (50 %, 65 %, and 80 % 1RM) on upper-body explosive performance in mixed martial arts (MMA) athletes, with emphasis on training status. Methods: Twenty-nine male MMA athletes were divided into intermediate (n = 14) and advanced (n = 15) groups. Each participant completed three CA sessions followed by a 4-minute recovery and then performed a plyometric push-up …

Evaluating Kansai Airport's Ppp: Grounded Ambitions, Concession Of Financial, Geotechnical, And Climate Risk, Edmund Cho, Dimitrios V. Siskos

International Journal of Aviation, Aeronautics, and Aerospace

This study critically examines the Kansai Airports Group’s 44-year Public-Private Partnership (PPP) monopoly-type concession encompassing Kansai International (KIX), Osaka Itami (ITM), and Kobe (UKB) airports. The research uses financial analysis, Monte Carlo simulation, and NPV-at-risk modeling to evaluate how Japan’s fixed-term private monopoly model allocates financial, operational, and environmental risks. In 2015, there were significant developments in the promotion of the Private Finance Initiative (PFI) Act. It was revised in 2015; as a result, it finds that the underestimated long-term maintenance liabilities, especially Kansai airport (KIX) foundation subsidence, and lacked flexibility to manage exogenous shocks like COVID-19 and Typhoon Jebi. …

A Transition Framework For Hybrid Tls In Enterprise-Level Systems, William Hadd

Cybersecurity Undergraduate Research Showcase

Enterprises face an immediate need to protect long-lived data against harvest-now, decrypt-later threats while maintaining interoperability across layered systems. With NIST’s first post-quantum standards finalized (ML-KEM, ML-DSA, SLH-DSA) and TLS hybridization drafts defining concrete ECDHE + ML-KEM groups, adoption can begin at the TLS termination layer even before full ecosystem support for post-quantum signatures arrives (NIST, 2024; IETF, 2025). In this paper, we propose an enterprise-oriented transition framework and maturity model for hybrid TLS across email, internal API gateways, and object storage. We specify where to enforce, which hybrid groups to select, and how to prevent silent downgrade with policy …

The Legal And Ethical Impacts Of Cybersecurity Practices On Privacy And Digital Rights, Ibrahim Fejzulla

Cybersecurity Undergraduate Research Showcase

The General Data Protection Regulation (GDPR) and the Health Insurance Portability and Accountability Act (HIPAA) are meant to secure our data, but sometimes it feels as if organizations don’t do enough to secure and protect our data and privacy. Even some of the things organizations may do to improve security may sound counterintuitive like hiring ethical hackers or penetration testers. This research looks at the effects both, the GDPR and HIPAA, have had on cybersecurity practices and policies of organizations. This paper aims to analyze the effects of both the GDPR and HIPAA, answer whether ethical hacking is justified, analyze …

Taking A Trip Into Nature’S Medicine Cabinet: A Country Comparison Of Efforts To Reschedule Psilocybin And Mdma For Therapeutic Use, Ariyah Jones

Georgia Journal of International & Comparative Law

No abstract provided.

Arbitrating Business And Human Rights Disputes In Latin America, Gloria Correa

Georgia Journal of International & Comparative Law

No abstract provided.

Fundamental Fairness Guides The Supreme Court's Criminal Justice Decisions In The 2024-2025 Term, Sharon R. Fairley

ConLawNOW

During the 2024-2025 term, the Supreme Court decided fifteen cases related to the criminal justice system. These cases were brought by criminal defendants seeking post-conviction relief and civil litigants seeking redress for governmental harms arising out of criminal processes. Remarkably, two-thirds of the cases resulted in decisions favoring defendants or civil litigants opposing the government. This Article argues that the pro-defendant outcomes from this term are consistent with a recent trend in the Court’s decisions favoring defendants in these types of cases. The pro-defendant outcomes from the 2024-2025 term generally resulted from the less conservative justices aligning with the liberal …

The Tax Adviser, Volume 1, Number 2, February 1970, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Audits, Business Abuses And Disciplinary Action, William H. Smith

Tax Adviser

No abstract provided.

Systematic Classification Of Recent Benthic Foraminifera In Socotra Island And Hadhramout Coastline And Their Environmental Significance, Wafa’A M. Al-Qadassi, Mohammed A. Al-Wosabi, Enas A. Ahmed

Sultan Qaboos University Journal For Science

This study explores the ecological significance of benthic foraminifera in the subtropical marine ecosystems of Socotra Island and the Hadhramout coastline, located in the Indian Ocean and Arabian Sea. A total of 216 species from 91 genera were identified in 32 surface sand samples collected during 2017 and 2018. The study examines how environmental factors including salinity, temperature, and substrate type affect the distribution of foraminifera. The results reveal that the assemblages and species diversity are distinct in each studied region, indicating a notable adaptability of foraminifera to specific environments. This work highlights the potential of benthic foraminifera as bioindicators …

Mineralogical, Chemical And Physical Properties Of Zeolite Minerals In The Maryah Area, Dhamar, Yemen, Amer M. Al-Sabri, Salah A. Al-Khirbash, Nabil M. Al-Areeq

Sultan Qaboos University Journal For Science

Natural zeolite minerals are a group of hydrated aluminosilicates known for their unique properties, including ion exchange, adsorption, and catalytic capabilities. This paper aims to delineate the mineralogical, chemical, and physical properties of natural zeolite minerals in the Maryah area, Dhamar, Yemen and highlight their significance in various applications such as agriculture, environment, and industry. The petrographic study indicates that the zeolitization processes occurred due to volcanic glass alteration. Based on the XRD pattern, it was found that the zeolite minerals are clinoptilolite and hollandite, which represent most of the mineral content, and they are among the common commercial types …

Antioxidant Status And Lipid Profile Of Experimental Rats Fed Animal Fat And Costus Afer Plant (Ker Gawl) Part Diets, Folake Lucy Oyetayo, Bukola Oluwagbemiga, Damilola Abosede Ojo

Sultan Qaboos University Journal For Science

Costus afer is an ethnomedicinal plant used in Africa for the management of hyperglycemia. Influences of Costus afer plant parts on key indicators linked to hyperlipidemia and antioxidant enzyme status were determined in this study. HPLC analysis displayed quercetin (67.84 μg/g) as the most dominant phenolic in the leaf. Seven rats were placed on commercial diet as control while forty-two rats placed on beef fat (tallow)/Animal fat diet (AFD) for two-weeks were randomly assigned into six dietary groups (2–7) of seven rats each viz; Group 1 normal diet, Group 2 animal fat diet (AFD), while Groups 3–7 pre-fed AFD rats …

Photocatalytic Activity Of The Mixed Of Ti/Fe/Mo Oxide Composites For Degradation Of Nitrofurazone, Dilshoda R. Tursunova, Zuhra Ch. Kadirova, Shahlo Sh. Daminova, Kadriya Kh. Gabidullina

CHEMISTRY AND CHEMICAL ENGINEERING

The aim of study is synthesize mixed oxide composites based on titanium dioxide, iron and molybdenum oxides from industrial waste materials and evaluated for their photocatalytic degradation performance of nitrofurazone—a persistent and toxic antibiotic frequently detected in aquatic environments. Various Ti/Mo ratios (T95M5, T87.5M12.5, T75M25, and T50M50) were prepared through thermal treatment at 600 °C and characterized using XRD, UV–Vis and Raman spectroscopy to assess structural and optical properties.XRD and Raman analyses confirmed the presence of anatase-phase TiO₂ and Mo/Fe oxides, with optimal crystallinity and heterojunction formation observed in the T87.5M12.5 composite. UV–Vis spectroscopic studies demonstrated that this composite exhibited …

The Impact Of Market And Nonmarket Strategies On Firm Performance In Lithuania, John A. Parnell, Michael W. Davidson

Economic and Business Review

This study examines the impact of market strategies (global growth, differentiation, and cost leadership) and nonmarket strategies (political engagement and social responsibility) on firm performance in Lithuania. Based on survey data from 114 managers analyzed using partial least squares structural equation (PLS-SEM) modeling, a global growth/differentiation strategy has a positive impact on performance, whereas cost leadership does not. Nonmarket strategies positively influence firm performance, with larger firms benefiting more, ostensibly due to greater resource availability and institutional influence. Firm size moderates the relationship between nonmarket strategies and performance, highlighting the importance of tailoring strategies to an organization's specific characteristics. By …

Development Of A Method For Using Effective Elements For The Storage Of Electrical Energy, Jasur M. Melibaev, Nasiba U. Abduraimova, Sardor S. Abriev, Yulbarskhon N. Mansurov

CHEMISTRY AND CHEMICAL ENGINEERING

The aim of the work is to find ways to use cryotic metals that also provide added value to the economy, using the example of tantalum and zirconium. Among the critical metals, there are those that are rarely found in the Earth’s crust but possess unique properties. These include tantalum and zirconium. While zirconium finds industrial applications, tantalum is still rarely used – its main application in capacitors for producing phones, computers, and automotive electronics. A small amount of tantalum is used to make hard alloy elements. Analysis showed that between zirconium and tantalum, there is a mixture of two …

Saudi Heart Association Position Statement On Adult Vaccinations For Patients With Cardiovascular Diseases, Waleed Alhabeeb, Fayssal M Farahat, Majid Alshamrani, Raed Aldahash, Mohamed S. Al-Moamary, Mohammed Balghith, Yassmin Hanfi

Journal of the Saudi Heart Association

Background: Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide. Individuals with CVD are particularly vulnerable to severe complications from vaccine-preventable infections; however, adult vaccination continues to be underutilized. Methods: A multidisciplinary expert panel from the Saudi Heart Association (SHA) conducted a comprehensive literature review and a series of consensus meetings to develop evidence-based recommendations for adult immunization in patients with CVD. Results and conclusions: Evidence from randomized trials, observational studies, and real-world data supports the role of vaccines in reducing the risk of major adverse cardiovascular events in individuals with CVD. The SHA recommends the implementation of age-appropriate …

Engaging Ukrainian Tf-Cbt Therapists In A Practice Skills Course To Support Their Wellbeing, Elisabeth Pollio, Esther Deblinger, Beth Cooper, Maike Garbade, Julie P Harrison, Elisa Pfeiffer

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Background: Burnout and secondary traumatic stress (STS) are common among therapists working with trauma-exposed clients, which can negatively impact them professionally and personally. The shared trauma of war exposure may put therapists at greater risk. To help support their wellbeing, an eight-session course was offered to Ukrainian therapists following training in Trauma-Focused Cognitive Behavioral Therapy (TF-CBT). This course involves therapists personally utilizing the PRACTICE skills taught to clients in TF-CBT for professional and personal benefit.

Objective: The objective was to gather preliminary evidence on the potential impact of implementing the course with Ukrainian therapists providing TF-CBT during a period of …

(R2127) On 2-Absorbing Hesitant Primary Fuzzy Ideals Of Rings, B. Anitha, M. Vidhya

Applications and Applied Mathematics: An International Journal (AAM)

By presenting 2-absorbing hesitant primary fuzzy ideals, we begin the investigation of a generalisation of hesitant primary fuzzy ideals (HPRFI) in rings in this research. The concepts of a weakly completely 2-absorbing hesitant primary fuzzy ideal (WC2-AHPRFI) and a Weakly completely 2-absorbing hesitant fuzzy ideal (WC2-AHFI) are developed, and their structural features and attributes are examined. We introduce the idea of a 2-absorbing hesitant K-fuzzy ideal (2-AHK-FI), 2-absorbing hesitant K-primary fuzzy ideal (2-AHK-PRFI) and examine a few of its characteristics.

(R2136) Dimensionless Modeling And Analytical Insights Into Botanical Biofiltration Systems For Voc Reduction, N. Jeeva, K. M. Dharmalingam, M. Veeramuni

Applications and Applied Mathematics: An International Journal (AAM)

This paper investigates the mathematical modeling of volatile organic compound (VOC) removal using a botanical biofiltration system, an effective biological treatment method. It examines mass balance concentrations in the gas and biofilm phases, highlighting their significance in VOC degradation and indoor air quality enhancement. The governing equations of the proposed model are converted into a dimensionless form, resulting in second-order nonlinear differential equations. Derived from mass transfer and reaction kinetics principles, these equations incorporate specific boundary conditions to capture gas-biofilm interactions and VOC removal dynamics in biofiltration. The modified Adomian decomposition method (MADM) is utilized to derive analytical solutions for …