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Articles 48661 - 48690 of 1791766
Full-Text Articles in Entire DC Network
Constitutional Rights, Human Dignity, And The American Dream: A Historical Analysis Of U.S. Immigration Policy After 9/11, Shelby Mcilroy
Constitutional Rights, Human Dignity, And The American Dream: A Historical Analysis Of U.S. Immigration Policy After 9/11, Shelby Mcilroy
CMC Senior Theses
This thesis examines how United States immigration policy transformed after September 11, 2001 and asks whether modern immigration enforcement remains consistent with constitutional principles, human rights protections, and the broader ideals associated with the American Dream. The project investigates how immigration shifted from a primarily civil administrative system into one increasingly defined by surveillance, detention, and punishment. The central question guiding this research is whether the securitization of immigration has reshaped not only enforcement practices, but also the meaning of constitutional protections and human dignity for both citizens and noncitizens.
To answer this question, this thesis conducts a historical policy …
Pesos For Pesos And No One Feels At Home: Gentrification And Displacement In Mexico City, Sophia L. Castellanos
Pesos For Pesos And No One Feels At Home: Gentrification And Displacement In Mexico City, Sophia L. Castellanos
CMC Senior Theses
This thesis investigates how gentrification and displacement have affected Mexico City, providing historical context and reasoning behind current policies for digital nomads and tourists. It examines policies enacted in similar cities such as Barcelona, Amsterdam, and Venice, which face challenges from increased tourism and short-term rentals like Airbnb. The thesis also reviews these regulations, highlighting their successes and limitations, and offers recommendations for integrating some of these strategies into Mexico City’s 2024 Tourism Law. Additionally, it explores public innovation strategies that could promote collaborations between the government and communities rather than complete government control. Finally, the paper discusses the challenges …
Family, Stability, Mentors & Money: Student Definitions Of Success, Arturo Caldera
Family, Stability, Mentors & Money: Student Definitions Of Success, Arturo Caldera
CMC Senior Theses
This research takes a deep dive into the factors shaping marginalized communities’ educational experiences, particularly for low-income Latino students from migrant backgrounds navigating public schooling spaces. Across sixteen qualitative interviews, participant narratives reveal how a systemic lack of resources at the institutional, interpersonal, and structural levels undermines the quality of support students receive and shapes their academic trajectories. Grounded in student-centered practices and informed by scholarship in multicultural education, Chicanx/Latinx studies, feminism, and psychology, this study contributes to ongoing efforts to move beyond deficit-based frameworks and instead recognize the cultural wealth, knowledge, and resilience students bring from their homes and …
From Statute To Classroom: The Implementation Gap In California's Queer-Relevant Sex Education Policy, Alejandro Quiroz-Novela
From Statute To Classroom: The Implementation Gap In California's Queer-Relevant Sex Education Policy, Alejandro Quiroz-Novela
CMC Senior Theses
This thesis examines why strong sex education laws do not reliably translate into consistent classroom experiences for LGBTQ+ students. Using a qualitative single-case study of California, it traces the evolution from SB 71 (2003) to the California Healthy Youth Act (CHYA) (2016) and analyzes how mandates move through a decentralized governance chain. Drawing on statutes, legislative records, state guidance, curriculum review tools, advocacy reports, media accounts, and public indicators, the study focuses on implementation mechanisms rather than estimating causal health effects. Three findings emerge: CHYA sets a clear legal floor but is difficult to verify at scale; district discretion and …
From Imbalance To Phenotype: Neurodevelopmental Alterations In Trisomy 21, Andrew Yuan
From Imbalance To Phenotype: Neurodevelopmental Alterations In Trisomy 21, Andrew Yuan
CMC Senior Theses
Down syndrome (DS), caused by Trisomy 21, is the most common genetic cause of intellectual disability. Individuals with DS consistently show reduced brain volume, decreased cortical thickness, and lasting impairments in learning, memory, and executive functioning. These neuroanatomical changes emerge during fetal development and are accompanied by chronic immune dysregulation due to the triplication of four interferon receptor genes on chromosome 21. Although decreased neuron progenitor proliferation has been known to contribute to these phenotypes, the precise timing and cellular mechanisms underlying disruptions in neurogenesis remain not fully understood. This study used immunohistochemistry to examine human fetal cortical tissue from …
Teaching A New Dog Old Tricks: How Buy Now Pay Later Responds To Consumer Financial Strength, Ryunosuke Nakase
Teaching A New Dog Old Tricks: How Buy Now Pay Later Responds To Consumer Financial Strength, Ryunosuke Nakase
CMC Senior Theses
This thesis aims to answer three questions. 1) How does BNPL usage in the US respond to macroeconomic conditions reflective of consumer strength? 2) Does BNPL debt migrate toward credit cards during months following high BNPL spend? 3) How does BNPL respond to macroeconomic conditions at the firm level? I constructed a 4 year monthly and quarterly time series dataset spanning from 2021 to 2025. I utilize time series OLS regressions to examine the short-term behavior of BNPL volume monthly at the aggregate level and quarterly at the firm level. At the aggregate level, BNPL volume in the US is …
Investor Reactions To Clinical Trial Outcomes: Interpreting Impacts Using Ai-Based Measures Of Investor Sentiment, Sofia K. Weinstein
Investor Reactions To Clinical Trial Outcomes: Interpreting Impacts Using Ai-Based Measures Of Investor Sentiment, Sofia K. Weinstein
CMC Senior Theses
This thesis examines how investors react to biotechnology firms’ clinical trial announcements and whether artificial intelligence (AI) can enhance our understanding of those market reactions. Using a representative sample of 95 firm-event observations between 2014 and 2025, the study measures cumulative abnormal returns (CARs) surrounding clinical readouts, regulatory decisions, and partnership disclosures. Event-study regressions test for heterogeneity across trial phase, therapeutic area, and textual sentiment derived from company press releases. Consistent with expectations, later-phase trials, particularly Phase II and III, produce stronger short-term abnormal returns. However, categorical variables such as phase or therapeutic area explain little of the total variation …
Has Liberalism Failed? Analyzing The New Right’S Critique Of Liberalism Through Its Historical Arc, Frederick (Gus) G. Mahler
Has Liberalism Failed? Analyzing The New Right’S Critique Of Liberalism Through Its Historical Arc, Frederick (Gus) G. Mahler
CMC Senior Theses
This paper examines the historical evolution of American political culture to evaluate whether liberalism is responsible for the social and political crises confronting the United States today. Although liberalism has been foundational to American governance and national identity since the country’s inception, a growing movement known broadly as the New Right now claims that it has failed and must be replaced. I seek to assess the legitimacy of this claim.
Using qualitative historical analysis, I trace how the form liberalism takes and the role it occupies in America’s political order has changed throughout the nation’s development. Liberalism was not always …
The Influence Of Injury Stimuli On Stress Levels In Female Rugby Players Post Injury., Hannah L. Maycock Miss
The Influence Of Injury Stimuli On Stress Levels In Female Rugby Players Post Injury., Hannah L. Maycock Miss
CMC Senior Theses
This article is a proposal of a study which explores the relationship between female rugby injuries and stress levels through measuring stress between different stimuli. I will recruit 195 participants from across the country to take part in the study. They will be assigned to one of three groups: no injury, ACL injury, and head injury based on their past injury experience. Their stress levels will be measured using the galvanic skin response measure, which will be used to compare the results of each group's stress throughout the study. The participants will all complete two measures of stress, one comparing …
Determinants Of The U.S. Experience Economy: A Macroeconomic, Demographic, And Technological Analysis, 1984–2023, Chloe Ross
CMC Senior Theses
Pine and Gilmore et al. 1999 examine American consumers’ preferences for experiences over durable goods. Since then, there has been a multitude of research on the psychology behind this shift in consumption preferences, and there has been an abundance of media coverage of the new “experience economy.” This thesis goes beyond psychology and examines the macroeconomic, demographic, and technological determinants of experiential spending in the United States from 1984 to 2023. I use annual data from the Bureau of Labor Statistics’ Consumer Expenditure Survey (CES) and variables from the Bureau of Economic Analysis (BEA), Federal Reserve Economic Data (FRED), US …
Medical And Recreational Cannabis In Colorado: Evidence From County-Level Sales And Medical Cards, Ethan Sattley
Medical And Recreational Cannabis In Colorado: Evidence From County-Level Sales And Medical Cards, Ethan Sattley
CMC Senior Theses
This thesis examines how Colorado’s cannabis market transitioned after recreational legalization by analyzing county-level medical card registrations and the medical share of cannabis sales from 2010–2020. Using an event-study design, I find that medical participation remained stable for several years after recreational sales began in 2014, but then declined sharply, by roughly 50–60 cards per 10,000 residents, about ten quarters after legalization. Using annual sales data, I show that the medical share of total cannabis revenue collapsed much more quickly, falling by more than half between 2014 and 2015 and converging near zero in most counties by the late 2010s. …
Auditor Independence And Its Impact On Debt Financing Outcomes, Harry Zhou
Auditor Independence And Its Impact On Debt Financing Outcomes, Harry Zhou
CMC Senior Theses
This study investigates whether perceived auditor independence, proxied through proportions of non-audit service fees and client dependence of the auditor, is associated with the outcome of debt contracts. While prior research examines how these proxies relate to auditor independence itself, and other strands of literature assess how audit quality influences debt contracting, few studies evaluate whether lenders interpret auditor independence signals in ways consistent with auditors. This study aims to contribute to the broader literature by examining the auditor independence proxies and its direct relationship to debt contract structure holistically. Two OLS models were employed to investigate the relationship between …
Beyond Bans: A Travel Distance-Based Approach To Estimating The Effects Of Dobbs V. Jackson Women’S Health Organization On Fertility And Labor Supply, Enya Kamadolli
CMC Senior Theses
The Dobbs v. Jackson Women’s Health Organization decision had highly heterogeneous effects on abortion access across U.S. states, variation I exploit to identify causal effects on fertility and labor supply. Rather than a binary “total ban” indicator, I construct a continuous treatment measure based on changes in distance to the nearest legal abortion provider between 2021 and 2023, and apply a difference-in-differences design to state-level panel data. Effects are attenuated and imprecise in the South, consistent with diminishing marginal effects at large distances. In non-Southern states, I find that a 100 km increase in distance raises total births by about …
Transformed, Not Resolved: Ethnic Federalism And The Politics Of Conflict In Ethiopia, Melayae L. Houser
Transformed, Not Resolved: Ethnic Federalism And The Politics Of Conflict In Ethiopia, Melayae L. Houser
CMC Senior Theses
This thesis investigates whether Ethiopia's system of ethnic federalism resolved the longstanding conflicts that have characterized the country's political history or instead transformed them into new manifestations. Introduced in 1991 after the collapse of the Derg regime, ethnic federalism reorganized Ethiopia into ethnically defined regional states and granted groups constitutional rights to self-governance and self-determination. The system aimed to address historical grievances stemming from decades of centralized, exclusionary governance.
Employing a four-part analytical framework, this thesis analyzes two case studies: the Tigray War of 2020–2022 and the Oromia-Somali border conflict, to argue that ethnic federalism did not resolve Ethiopia's underlying …
David Vs. The Propaganda Machine: Péter Magyar And The Disruption Of Hungary’S Media Capture, Carrick G. Mollenkamp
David Vs. The Propaganda Machine: Péter Magyar And The Disruption Of Hungary’S Media Capture, Carrick G. Mollenkamp
CMC Senior Theses
The durability of competitive authoritarian regimes is often derived from media capture, a sophisticated system in which media institutions are structured to favor incumbent actors. Viktor Orbán’s Hungary serves as a quintessential example. For more than a decade, opposition actors were systematically denied meaningful access to the electorate, enabling Orbán to maintain his grip on power through consecutive elections. But that durability did not last. Drawing on Marius Dragomir’s media capture model and Steven Levitsky and Lucan Way’s framework of hybrid regimes, this thesis argues Péter Magyar’s landslide victory in the 2026 Hungarian parliamentary election exposed three vulnerabilities of media …
The Economics Of The U.S. Student Loan Market And The Case For The Education Development Financial Institution, Ian Akers
CMC Senior Theses
The United States student loan market is shaped by a variety of market failures–credit constraints, positive externalities, behavioral frictions including myopia, debt aversion, and misperception–that together justify government intervention in the market. Yet the design of federal intervention is just as important as its existence. This thesis details the economic theory underpinning the market for student loans, evaluates three historical federal student loan programs (the Perkins Loan Program, the Federal Family Education Loan Program, and the Federal Direct Loan Program) through the lens of that theory. The thesis then proposes a novel institutional model as a targeted response to the …
Pillpetz: A Smarter Way To Encourage Medication Adherence In Children, John H. Begley
Pillpetz: A Smarter Way To Encourage Medication Adherence In Children, John H. Begley
CMC Senior Theses
Medication adherence is usually framed as a problem of patient behavior, but this thesis argues that it is equally a problem of design. Children who take daily medication face barriers that adults often do not: developing executive function, dependence on caregivers, shifting school and home routines, privacy concerns, and stigma around being perceived as different. The standard prescription bottle, by contrast, was designed primarily for dispensing efficiency, safety, and accidental ingestion prevention—not for sustained daily use by a developing child.
This thesis proposes PillPetz, a smart pill case and digital companion that uses routine, play, dose confirmation, and caregiver-connected support …
Algorithmic Trading In Idiosyncratic-Payoff Markets: A Multi-Agent System For On-Chain Prediction Contracts, Saif Aldeen A.K. Agha
Algorithmic Trading In Idiosyncratic-Payoff Markets: A Multi-Agent System For On-Chain Prediction Contracts, Saif Aldeen A.K. Agha
CMC Senior Theses
This thesis documents the design, deployment, and forward-test evaluation of an evolutionary multi-agent algorithmic trading system on Polymarket, the largest decentralized prediction market. The system pairs a locally-hosted 72-billion-parameter language model with a gradient-boosted statistical filter and an evolutionary selection mechanism that maintains a population of approximately 500 autonomous trading agents. Each agent generates a probability estimate for an event, compares it to the prevailing market price, and trades the resulting disagreement.
The central empirical exercise estimates a panel regression of trade-level profit on the absolute disagreement between the agent's probability estimate and the market price, controlling for agent identity, …
From Reconstruction To The Carceral State: Law, Labor, And Punishment In Black America, Nicolas S. Changbencharoen
From Reconstruction To The Carceral State: Law, Labor, And Punishment In Black America, Nicolas S. Changbencharoen
CMC Senior Theses
This thesis examines the reconfiguration of racial and labor subordination in the United States from Reconstruction to the present, arguing that the legal abolition of slavery did not dismantle the economic and institutional structures on which it rested. It traces a continuous trajectory through which law and the criminal justice system were systematically weaponized to reconstitute slavery's essential functions under successive institutional forms, each serving as a deliberate mechanism for the extraction of Black labor in service of private and state interests. The analysis culminates in an examination of the modern carceral state, concluding that contemporary prison labor programs continue …
Goods, Practices, Excellence, And The Law: Steps To An Internal Theory Of Value, Rowan Gray
Goods, Practices, Excellence, And The Law: Steps To An Internal Theory Of Value, Rowan Gray
CMC Senior Theses
Practices are the coherent and complex social activities we spend much of our lives engaging in. This category encompasses everything from figure skating to wine-tasting to friend relationships. We gain immense value from participating in practices, and philosophers have articulated a number of accounts for where the value emerges from and how we can best experience it. Many of these theories are ‘externalist’, because they posit that value is incidental to practices and emerges from outside of them.
In contrast, this thesis will argue that the value in practices is internal to each practice. The value comes from each practice’s …
Designed To Please: How Sycophantic Ai Voices Reinforce Gendered Expectations, Zoe O. Feuer
Designed To Please: How Sycophantic Ai Voices Reinforce Gendered Expectations, Zoe O. Feuer
CMC Senior Theses
Scholars have raised concerns that the popularization of feminized, agreeable AI assistants normalizes associations between women and subservient behavior, potentially reinforcing broader gender stereotypes through repeated exposure. This study tested whether AI sycophancy and AI gender shape user perceptions of AI warmth, competence, affective trust, and cognitive trust, and whether interacting with a sycophantic female AI shifts explicit or implicit gender stereotype endorsement. Using a 2 (AI gender: male vs. female) × 2 (sycophancy: high vs. low) between-subjects design, 202 participants completed a simulated travel planning task with a voice-based AI agent. Despite successfully manipulating sycophancy, neither sycophancy nor AI …
Top-Tier Venture Capital Backing And Startup Acquisition Speed: Evidence Of Certification Signaling In Private Markets, Nicolas Wilde
Top-Tier Venture Capital Backing And Startup Acquisition Speed: Evidence Of Certification Signaling In Private Markets, Nicolas Wilde
CMC Senior Theses
The venture capital market is defined by information asymmetry, and private acquisitions represent the setting where that asymmetry bites hardest. Acquirers evaluating private targets have no prospectus, no analyst coverage, and no independent market price to anchor their judgment. This paper asks whether the reputation of a startup's lead investor shapes how quickly that startup is acquired. Using a sample of 1,000 acquired United States technology startups founded between 2008 and 2016, sourced from Crunchbase, I estimate a cross-sectional OLS regression of months from founding to acquisition on a binary indicator of top-tier venture capital backing based on the 2016 …
Modulating Oran Nitrate-Reducing Bacteria To Enhance Nitric Oxide Bioavailability As A Therapeutic Target For Atherosclerosis, Donovan C. Davidson
Modulating Oran Nitrate-Reducing Bacteria To Enhance Nitric Oxide Bioavailability As A Therapeutic Target For Atherosclerosis, Donovan C. Davidson
CMC Senior Theses
Atherosclerosis remains the primary driver of global cardiovascular disease, yet clinical interventions are largely restricted to high-cost, invasive procedures only after it has reached a critical stage. Recent research has identified a connection between the oral microbiome and vascular health via the enterosalivary nitrate-nitrite-nitic oxide (NO) pathway. Oral nitrate-reducing bacteria (ONRB) drive the synthesization of NO by reducing dietary nitrate into nitrite, which is then converted into bioavailable NO. NO is a potent vasodilator that maintains endothelial health by suppressing inflammation through inhibiting the expression of adhesion molecules VCAM-1 and ICAM-1. However, this pathway is easily compromised by dysbiotic oral …
Not Biological, But Built: Structural And Metabolic Pathways Driving Black Maternal Health Disparities In The United States, Alexandra I. Umegboh
Not Biological, But Built: Structural And Metabolic Pathways Driving Black Maternal Health Disparities In The United States, Alexandra I. Umegboh
CMC Senior Theses
Black infants in the United States are more than twice as likely to die before their first birthday than white infants, a disparity often attributed to genetics, behavior, or individual health choices. However, this idea is challenged by a key contradiction: African immigrant women consistently experience better birth outcomes than U.S.-born Black women despite being similarly racialized. This thesis investigates the origins of this reproductive advantage and the factors contributing to its decline over time. By drawing on epidemiological data, metabolic health research, and literature on African diasporic healing traditions, it argues that the “healthy immigrant effect” is not biological, …
Balancing The Scales Of Justice: The Unconstitutionality Of Marital Rape In India, Pallavi Raju
Balancing The Scales Of Justice: The Unconstitutionality Of Marital Rape In India, Pallavi Raju
CMC Senior Theses
Marital rape remains an unpunished crime in India, despite decades of dispute and litigation. This thesis explores the question of why the state continues to retain the marital rape exception within the Indian criminal code, even though it commits to combat gender based violence in other areas of justice. The research begins with a broader understanding of privatization of women’s rights in the international sphere and culturally sanctioned violence to protect the institution of marriage. With a focus on the legal justifications and language of Indian court cases, this thesis determines that judges adjudicate on gender justice inconsistently. Attempting to …
The Jamaica That Dreams: A Normative Application Of Developmental Theory, Tamoy Pitt
The Jamaica That Dreams: A Normative Application Of Developmental Theory, Tamoy Pitt
CMC Senior Theses
This thesis examines Jamaica’s persistent underdevelopment through Martha Nussbaum's normative application of the capabilities approach as per her conception in Creating Capabilities. Through this approach, the paper will argue that Jamaica’s underdevelopment is a result of the failure of its domestic institutions to provide all citizens with the substantive freedoms and capabilities necessary to live lives of dignity. Originally detailed by Amartya Sen in his book Development as Freedom, the capabilities approach posits freedom as both the means and ends to development while rejecting contemporary approaches to development such as GDP, Utilitarianism, or Rawlsian resource-based approaches as insufficient frameworks for …
Defining Consensus‐Based Components For Integrating Dietitians Into Primary Dental Care For Paediatric Populations: A Delphi Study, Lauren Hallewell, Raul Bescos, Zoe Brookes, Robert Witton, Patricia Casas‐Agustench
Defining Consensus‐Based Components For Integrating Dietitians Into Primary Dental Care For Paediatric Populations: A Delphi Study, Lauren Hallewell, Raul Bescos, Zoe Brookes, Robert Witton, Patricia Casas‐Agustench
School of Health Professions
Background: Diet is a modifiable risk factor linking oral and systemic health, contributing to dental caries and weight-related outcomes (including underweight, overweight and obesity) in the paediatric population. However, dietary advice provided by dental professionals in primary dental care is often brief and sugar-focused, representing a missed opportunity to address shared risk factors. Integrating dietitians into primary dental care may support more holistic paediatric preventative care. Objective: To develop expert consensus on the components required to integrate dietitians into primary dental care to address diet as a common risk factor in paediatric oral health and weight-related outcomes. Methods: A three-round …
Exploring The Views Of Children With Cerebral Palsy, Their Parents And Physiotherapists On Participating In A Feasibility Randomised Controlled Trial Testing An Exergaming Device: A Qualitative Study, Rachel Rapson, Jos M. Latour, Jonathan Marsden, Bernie Carter
Exploring The Views Of Children With Cerebral Palsy, Their Parents And Physiotherapists On Participating In A Feasibility Randomised Controlled Trial Testing An Exergaming Device: A Qualitative Study, Rachel Rapson, Jos M. Latour, Jonathan Marsden, Bernie Carter
School of Nursing and Midwifery
Background: This study aimed to understand the experiences and views of children with cerebral palsy, their parents and physiotherapists participating in the ACCEPT feasibility randomised controlled trial, which explored a 10-week physiotherapy intervention using an interactive gaming training device. Design: Qualitative methods included semi-structured interviews, e-diary and photographs. Nine parent–child dyads and three physiotherapists participated. Children were aged between 7 and 16 years; four had co-existing additional needs. Interviews were transcribed. Reflexive thematic analysis was used. Results: Five themes covered the breadth of participants’ experiences: (1) Fitting in therapy; (2) Motivation; (3) New opportunities; (4) Physiotherapists out of their comfort …
Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes., Huanwen Chen, Marco Colasurdo, Hidetoshi Matsukawa, Conor Cunningham, Ilko Maier, Sami Al Kasab, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M. Starke, Marios-Nikos Psychogios, Edgar A. Samaniego, Nitin Goyal, Shinichi Yoshimura, Hugo Cuellar, Jonathan A. Grossberg, Ali Alawieh, Ali Alaraj, Mohamad Ezzeldin, Daniele G. Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Fazeel Siddiqui, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S. Park, Michael R. Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Ergun Daglioglu, Richard Williamson, Pedro Navia, Reade De Leacy, Shakeel Chowdhry, David J. Altschul, Alejandro M. Spiotta, Peter Kan
Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes., Huanwen Chen, Marco Colasurdo, Hidetoshi Matsukawa, Conor Cunningham, Ilko Maier, Sami Al Kasab, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M. Starke, Marios-Nikos Psychogios, Edgar A. Samaniego, Nitin Goyal, Shinichi Yoshimura, Hugo Cuellar, Jonathan A. Grossberg, Ali Alawieh, Ali Alaraj, Mohamad Ezzeldin, Daniele G. Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Fazeel Siddiqui, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S. Park, Michael R. Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Ergun Daglioglu, Richard Williamson, Pedro Navia, Reade De Leacy, Shakeel Chowdhry, David J. Altschul, Alejandro M. Spiotta, Peter Kan
Department of Medicine Faculty Papers
INTRODUCTION: Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear.
PATIENTS AND METHODS: This was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in …
Digital Cognitive Behavioral Therapy Versus Education For Chronic Pain In Adults With Sickle Cell Disease: 12-Month Randomized Trial Results, Olubusola B. Oluwole, Yi-Fan Yi-Fan Chen, Christina M. Lalama, Julia A. O’Brien, Laura M. De Castro, Charles Patrick Carroll, Darla Liles, Nirmish Shah, Santosh L. Saraf, Victor R. Gordeuk, Leshana Saint Jean, Michael Debaun, Robert M. Cronin, Tonya M. Palermo, Sherif M. Badawy, Megan E. Hamm, Jennifer N. Stinson, Chitra Lalloo, Sophie Lanzkron, Cassandra Trimnell, Lakiea Bailey, Raymona H. Lawrence, Kaleab Z. Abebe, Charles R. Jonassaint
Digital Cognitive Behavioral Therapy Versus Education For Chronic Pain In Adults With Sickle Cell Disease: 12-Month Randomized Trial Results, Olubusola B. Oluwole, Yi-Fan Yi-Fan Chen, Christina M. Lalama, Julia A. O’Brien, Laura M. De Castro, Charles Patrick Carroll, Darla Liles, Nirmish Shah, Santosh L. Saraf, Victor R. Gordeuk, Leshana Saint Jean, Michael Debaun, Robert M. Cronin, Tonya M. Palermo, Sherif M. Badawy, Megan E. Hamm, Jennifer N. Stinson, Chitra Lalloo, Sophie Lanzkron, Cassandra Trimnell, Lakiea Bailey, Raymona H. Lawrence, Kaleab Z. Abebe, Charles R. Jonassaint
Department of Medicine Faculty Papers
Background: Chronic pain affects up to 40% of adults with sickle cell disease (SCD), yet treatment options remain limited. While cognitive behavioral therapy (CBT) is effective in other chronic pain conditions, it is underutilized for SCD pain, and its effectiveness remains unclear. Purpose: The Cognitive Behavioral Therapy and Real-time Pain Management Intervention for Sickle Cell via Mobile Applications (CaRISMA) compared digital CBT to Education for chronic SCD pain in adults. At 6 months, the primary outcome (pain interference) showed no between-group difference but both groups improved (CBT: −2.13; Education: −2.66). This report presents 12-month outcomes. Methods: A total of 359 …