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Articles 42211 - 42240 of 1792131
Full-Text Articles in Entire DC Network
When Targeted Gene Testing Falls Short: Case Report Of A Novel Slc4a3 F347s Genetic Variant Associated With Short Qt Syndrome, Chelsea A Boyd, Tyler J Novy, Taylor A Beecroft-Dawson, Connor A Bell, Emily M Bland, Christina Y Miyake
When Targeted Gene Testing Falls Short: Case Report Of A Novel Slc4a3 F347s Genetic Variant Associated With Short Qt Syndrome, Chelsea A Boyd, Tyler J Novy, Taylor A Beecroft-Dawson, Connor A Bell, Emily M Bland, Christina Y Miyake
Faculty, Staff and Students Publications
No abstract provided.
Mindful Diagnostics In Culture-Negative Endocarditis: Early Noninvasive Diagnosis Of Tropheryma Whipplei By Plasma Microbial Cell-Free Dna, Ashita Jain, Sarwat Khalil, Muhammad R Sohail, Laura C Lelenwa, Enrique Garcia-Sayan, Kenneth K Liao, Ahmed Hamdi, Todd Lasco, Mayar Al Mohajer
Mindful Diagnostics In Culture-Negative Endocarditis: Early Noninvasive Diagnosis Of Tropheryma Whipplei By Plasma Microbial Cell-Free Dna, Ashita Jain, Sarwat Khalil, Muhammad R Sohail, Laura C Lelenwa, Enrique Garcia-Sayan, Kenneth K Liao, Ahmed Hamdi, Todd Lasco, Mayar Al Mohajer
Faculty, Staff and Students Publications
Tropheryma whipplei was identified by plasma microbial cell-free DNA sequencing within 4 days in severe culture-negative endocarditis after antibiotics had already been started. The result supported earlier diagnostic clarification and antimicrobial de-escalation before valve pathology was available, illustrating a practical diagnostic-stewardship role for noninvasive sequencing in high-acuity endocarditis.
Midterm Outcomes Of The Self-Expanding Navitor Transcatheter Heart Valve: A Systematic Review And Meta-Analysis., Sahar Samimi, Chloe Kharsa, Mangesh Kritya, Joe Aoun, Syed Zaid, Nadeen N Faza, Stephen H Little, Neal S Kleiman, Michael J Reardon, Sachin S Goel
Midterm Outcomes Of The Self-Expanding Navitor Transcatheter Heart Valve: A Systematic Review And Meta-Analysis., Sahar Samimi, Chloe Kharsa, Mangesh Kritya, Joe Aoun, Syed Zaid, Nadeen N Faza, Stephen H Little, Neal S Kleiman, Michael J Reardon, Sachin S Goel
Faculty, Staff and Students Publications
- A 19-study meta-analysis (7743 patients) found high Navitor technical/device success.
- ≥Moderate PVL was low: 1.3% at 30 days and 0.6% at 1 year.
- Pacemaker implantation was 16.7% at 30 days and 20.4% at 1 year.
- Thirty-day outcomes were favorable: all-cause mortality 1.5% and stroke 1.7%.
Pd-L1-Centric Whole Blood-Based Immune Signature Profiles Of Tuberculosis Patients During Therapy, Johanna Eggeling, Martina Sester, Christoph Lange, Jan Heyckendorf, Barbara Kalsdorf, Anna M Mandalakas, Andrew R Dinardo, David Lewinsohn, Dagmar Schaub, Tina Schmidt, Eva Tolosa, Maja Reimann, Patricia M Sánchez Carballo
Pd-L1-Centric Whole Blood-Based Immune Signature Profiles Of Tuberculosis Patients During Therapy, Johanna Eggeling, Martina Sester, Christoph Lange, Jan Heyckendorf, Barbara Kalsdorf, Anna M Mandalakas, Andrew R Dinardo, David Lewinsohn, Dagmar Schaub, Tina Schmidt, Eva Tolosa, Maja Reimann, Patricia M Sánchez Carballo
Faculty, Staff and Students Publications
This prospective study investigated whole blood-based immune cell biomarkers for pulmonary tuberculosis (TB) immunoprofiling. Blood samples from 34 healthy controls and 51 tuberculosis patients were analyzed at three timepoints: Prior to therapy (T0), after 14 days of therapy (T1), and at the end of treatment (Te). Using multiparameter flow cytometry, 386 immune cell populations were analyzed. Predictive models were developed using two machine learning algorithms. A TB5LF change score, which was based on five cell populations, effectively distinguished tuberculosis patients from controls (AUC = 0.89) and tuberculosis patients before and at the end of treatment (AUC = 0.92). Similarly, the …
A Year In Review On Tuberculosis And Non-Tuberculous Mycobacteria Disease: A 2026 Update For Clinicians And Scientists, Simone Tunesi, Graham Bothamley, Gunar Günther, Yousra Kherabi, Liga Kuksa, Berit Lange, Christoph Lange, Natalie Lorent, Francesca Saluzzo, Martina Sester, Xenia Emilie Sinding Iversen, Marc Tebruegge, Conor Tweed, Anca Vasiliu, Lorenzo Guglielmetti, Tuberculosis Network European Trials Group (Tbnet)
A Year In Review On Tuberculosis And Non-Tuberculous Mycobacteria Disease: A 2026 Update For Clinicians And Scientists, Simone Tunesi, Graham Bothamley, Gunar Günther, Yousra Kherabi, Liga Kuksa, Berit Lange, Christoph Lange, Natalie Lorent, Francesca Saluzzo, Martina Sester, Xenia Emilie Sinding Iversen, Marc Tebruegge, Conor Tweed, Anca Vasiliu, Lorenzo Guglielmetti, Tuberculosis Network European Trials Group (Tbnet)
Faculty, Staff and Students Publications
Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, while infections from non-tuberculous mycobacteria (NTM) represent a growing public health threat. In its 20th year of activity, the Tuberculosis Network European Trials group (TBnet; www.tbnet.eu) is one of the leading research networks in Europe. In this review, we summarize the main advances in TB and NTM that occurred in 2025.
Methods: We conducted a non-systematic review of articles published in 2025, with a strong emphasis on research with current or potential impact on clinical practice. We also selected the most impactful papers regarding the management of adult …
Beyond Mean Length Of Utterance: Novel Measures For Characterizing The Spoken Language Of Autistic Children, Janine Mathee-Scott, Courtney E. Venker
Beyond Mean Length Of Utterance: Novel Measures For Characterizing The Spoken Language Of Autistic Children, Janine Mathee-Scott, Courtney E. Venker
Speech Pathology and Audiology Faculty Research and Publications
Purpose:
Mean length of utterance (MLU) is a common measure of expressive language complexity in young children, including autistic children. However, means, by nature, obscure some information about spread and variability in data. Thus, we aimed to examine a new approach to characterizing linguistic complexity in autistic children by investigating the validity of two novel measures—range of length of utterance (RLU), standard deviation of length of utterance (SDLU)—alongside established measures: MLU and total utterances (TU).
Method:
Participants were 40 autistic children (12 girls, 28 boys; Mage = 41.78 months). Children participated in 10-min, play-based language samples with their caregivers. …
Improving Compliance With Safe Sleep Guidelines For Vulnerable Patients In A Community Safety Net Hospital Neonatal Intensive Care Unit, Andrew Beverstock, Samantha Carlton, Hillary Lee, Thomas Lu, Kelsi Morgan, Ashlee Smith-Patel, Kelli Phillips, Joseph Hagan, Pablo Lohmann, Caraciolo Fernandes, Lisa Owens, Daniela Dinu
Improving Compliance With Safe Sleep Guidelines For Vulnerable Patients In A Community Safety Net Hospital Neonatal Intensive Care Unit, Andrew Beverstock, Samantha Carlton, Hillary Lee, Thomas Lu, Kelsi Morgan, Ashlee Smith-Patel, Kelli Phillips, Joseph Hagan, Pablo Lohmann, Caraciolo Fernandes, Lisa Owens, Daniela Dinu
Faculty, Staff and Students Publications
Introduction: Modeling safe sleep in the neonatal intensive care unit (NICU) increases the likelihood that parents will follow these practices after discharge. Many NICU infants are put to sleep unsafely, and unsafe sleep practices are the leading cause of nonnatural death among children locally. We created safe sleep standards for infants older than 32 weeks based on national guidelines: infants should be placed supine in a flat, empty crib and should never be swaddled loosely. We aimed to increase the weekly percentage compliance with safe sleep recommendations from a baseline of 58% (0.58 compliant) to 85% (0.85 compliant) by March …
A Review Of Current Research And Barriers To Access: Exploring Disparities In Pediatric Epilepsy Surgery, Nikita Das, Ali A Mohamed, Akshat Katyayan, Meena Vessell
A Review Of Current Research And Barriers To Access: Exploring Disparities In Pediatric Epilepsy Surgery, Nikita Das, Ali A Mohamed, Akshat Katyayan, Meena Vessell
Faculty, Staff and Students Publications
Background: Drug-resistant epilepsy (DRE) impacts at least 30% of pediatric epilepsy patients, adversely affecting neurodevelopment and quality of life, as well as risk of sudden unexplained death in epilepsy (SUDEP). While surgical intervention has proven to be an effective treatment for DRE, disparities in access to surgical care persist. Compared to adults, pediatric patients face unique challenges, including delayed recognition of surgical candidacy, limited access to specialized epilepsy centers, complex care coordination, and socioeconomic barriers.
Summary: This review explores the current state of pediatric epilepsy surgery, highlighting its effectiveness in achieving seizure freedom, improving neurocognitive outcomes, and reducing long-term healthcare …
Layers To Leaves: A Suite Of Modular 3d Printed Hydroponics Components For Research And Education, Ethan A Shaw, Suraj K Chandramouli, Michael P Dzakovich
Layers To Leaves: A Suite Of Modular 3d Printed Hydroponics Components For Research And Education, Ethan A Shaw, Suraj K Chandramouli, Michael P Dzakovich
Faculty, Staff and Students Publications
Hydroponics is a widely utilized technique to precisely control the plant growing environment and maximize productivity. In some cases, hydroponics systems can be expensive and require specialized expertise to build and maintain. Here, we present a suite of 3D-printed devices that can be constructed into a single or double tower hydroponics system of variable height and composition. This system is easily scalable to fit the needs of a user and can be implemented in a variety of research and educational contexts. Components in this suite can be made from inexpensive plastic filament using household-grade 3D printers. The vertical design of …
Association Of Alcohol Use With Helmet Use In Cyclists: Analysis Of The National Trauma Data Bank, Daniel C Brock, Gaibo Yan, Chad T Wilson, Emanuel Narcis Husu
Association Of Alcohol Use With Helmet Use In Cyclists: Analysis Of The National Trauma Data Bank, Daniel C Brock, Gaibo Yan, Chad T Wilson, Emanuel Narcis Husu
Faculty, Staff and Students Publications
Background: Helmet use significantly reduces the risk of traumatic brain injury among cyclists; however, the influence of alcohol use on helmet-wearing adherence remains understudied in large national data sets. The goal of this study was to investigate the relationship between alcohol use and helmet use in injured cyclists.
Methods: This study is a retrospective cross-sectional analysis of 155 766 cyclists with traumatic injuries from the National Trauma Data Bank spanning 8 years (2017-2023). Cyclists were categorized by blood alcohol concentration (BAC) as follows: not screened, sober (BAC < 0.02), impaired (BAC 0.02-0.08), intoxicated (BAC ≥0.08), and multidrug intoxicated (BAC ≥0.08 plus ≥1 positive drug screen). The primary outcome was helmet usage. Secondary outcomes included mortality, hospital and intensive care unit length of stay, Injury Severity Score, and adverse events. Comorbid substance use disorders were considered as covariates.
Results: Alcohol use was associated with a dose-response decrease in helmet use. Helmet …
Phase I Study Of Niraparib With Radiotherapy For Treatment Of Metastatic And Locally Advanced Invasive Carcinoma Of The Cervix (Nivix), Piyush Pathak, Eunji Jo, Susan Hilsenbeck, Matthew L Anderson, Alfredo Echeverria, Shelly Sharma, Jan Sunde, Tracilyn Hall, Anthony Costales, Claire Hoppenot, Michelle Ludwig
Phase I Study Of Niraparib With Radiotherapy For Treatment Of Metastatic And Locally Advanced Invasive Carcinoma Of The Cervix (Nivix), Piyush Pathak, Eunji Jo, Susan Hilsenbeck, Matthew L Anderson, Alfredo Echeverria, Shelly Sharma, Jan Sunde, Tracilyn Hall, Anthony Costales, Claire Hoppenot, Michelle Ludwig
Faculty, Staff and Students Publications
Introduction: This Phase I study evaluated the safety and tolerability of concurrent niraparib, an oral poly(ADP-ribose) polymerase (PARP) 1/2 inhibitor, with definitive radiotherapy in women with locally advanced or platinum-sensitive metastatic cervical cancer. Dose escalation followed a Bayesian Optimal Interval (BOIN) design with a target dose-limiting toxicity (DLT) rate of 30%.
Methods: Women ≥18 years with FIGO stage IIIC2 (bulky nodes >1 cm) or stage IV cervical cancer demonstrating response to platinum-based induction chemotherapy were eligible. Niraparib 100 mg was administered daily concurrent with pelvic radiotherapy (45-57.5 Gy via IMRT with nodal boosts) and brachytherapy, continuing 28 days post-radiation. Per …
Comparing Rotational Thromboelastometry And Standard Coagulation Assays For Predicting Intraoperative Bleeding In Pediatric Liver Transplantation, Kirby Deshotels, Trung Nguyen, Jun Teruya, Muhammed Umair M Mian, Kelby Fuller, Sanjiv Harpavat, Anna Banc-Husu, Amir Navaei, John Goss, Moreshwar Desai, Arun Saini
Comparing Rotational Thromboelastometry And Standard Coagulation Assays For Predicting Intraoperative Bleeding In Pediatric Liver Transplantation, Kirby Deshotels, Trung Nguyen, Jun Teruya, Muhammed Umair M Mian, Kelby Fuller, Sanjiv Harpavat, Anna Banc-Husu, Amir Navaei, John Goss, Moreshwar Desai, Arun Saini
Faculty, Staff and Students Publications
Background: Utility of preoperative rotational thromboelastometry (ROTEM) over standard coagulation assays (SCAs) in predicting intraoperative bleeding during orthotopic liver transplantation (OLT) in children with liver failure (LF) remains unclear.
Methods: In this single-center retrospective cohort of pediatric OLT recipients, we compared the predictive values of preoperative ROTEM parameters (intrinsic pathway (INTEM) maximum clot firmness (MCF), extrinsic pathway (EXTEM) clotting time (CT), INTEM CT, and fibrinogen-based (FIBTEM) MCF) and the corresponding SCAs (platelet count, international normalized ratio (INR), activated partial thromboplastin time (aPTT), and fibrinogen level, respectively) for significant intraoperative bleeding (blood loss of > 22 mL/kg; i.e., ≥ 85th percentile for …
Modulation Of Corneal Sensory Processing And Pain Responses By Dry Eye And Corneal Wounding, Ebru Yaman, Yangluowa Qu, Kaylin C Arpaia, Fairouz Elsaeidi, Uma Lakshmi Balakrishnan, Lance He, Henry Skrehot, Jehan Alam, Rui Chen, Mary Ann Stepp, Cintia S De Paiva, Stephen C Pflugfelder
Modulation Of Corneal Sensory Processing And Pain Responses By Dry Eye And Corneal Wounding, Ebru Yaman, Yangluowa Qu, Kaylin C Arpaia, Fairouz Elsaeidi, Uma Lakshmi Balakrishnan, Lance He, Henry Skrehot, Jehan Alam, Rui Chen, Mary Ann Stepp, Cintia S De Paiva, Stephen C Pflugfelder
Faculty, Staff and Students Publications
Background: Dry eye disease (DED) is a multifactorial disorder of the ocular surface in which tear film instability, epithelial barrier disruption, and neurosensory dysfunction contribute to symptom generation. Although several contributing factors have been identified, how different forms of ocular surface stress affect sensory pathways and behavioral responses remains unclear.
Purpose: This study aimed to evaluate corneal barrier function, sensory responses, and pain-related behaviors across acute and chronic dry eye and corneal injury models, and to assess stimulus-specific responses associated with TRPV1 and TRPM8 mediated pathways.
Methods: Female C57BL/6 J wild type and Mmp9KO mice were evaluated in acute desiccating …
Differences In Gene Expression May Contribute To The Racial Differences In The Risk Of Masld, Ivan P Gorlov, Olga Y Gorlova, Aaron P Thrift
Differences In Gene Expression May Contribute To The Racial Differences In The Risk Of Masld, Ivan P Gorlov, Olga Y Gorlova, Aaron P Thrift
Faculty, Staff and Students Publications
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), exhibits marked racial disparities in incidence, progression, and clinical outcomes. While diet, lifestyle, and socioeconomic factors have been shown to influence these disparities, biological mechanisms underlying racial differences in MASLD risk remain poorly understood. We hypothesized that race-associated variation in hepatic gene expression may contribute to differential susceptibility and progression of MASLD. To test this hypothesis, we analyzed publicly available gene expression data from liver biopsies obtained from over 300 Black and White individuals undergoing bariatric surgery. Gene expression profiles were compared across four histological stages: …
Discovery Of Genetic Susceptibility Variants In Pediatric And Adult Ependymoma, Joshua D Strauss, Priya B Shetty, Spiridon Tsavachidis, Jinyoung Byun, Stephen C Mack, Xiao Xiangjun, Terri S Armstrong, Mark R Gilbert, (On Behalf Of Nci-Connect);, Lisa Mirabello, Smita Bhatia, Wendy M Leisenring, Lindsay M Morton, Gregory T Armstrong, Jon Foss-Skiftesvik, Christian Munch Hagen, Jonas Bybjerg-Grauholm, (On Behalf Of Gicc), Manel Ghozal, Audrey Bonaventure, Jacqueline Clavel, Melissa L Bondy, Christopher I Amos, Thanh T Hoang, Michael E Scheurer
Discovery Of Genetic Susceptibility Variants In Pediatric And Adult Ependymoma, Joshua D Strauss, Priya B Shetty, Spiridon Tsavachidis, Jinyoung Byun, Stephen C Mack, Xiao Xiangjun, Terri S Armstrong, Mark R Gilbert, (On Behalf Of Nci-Connect);, Lisa Mirabello, Smita Bhatia, Wendy M Leisenring, Lindsay M Morton, Gregory T Armstrong, Jon Foss-Skiftesvik, Christian Munch Hagen, Jonas Bybjerg-Grauholm, (On Behalf Of Gicc), Manel Ghozal, Audrey Bonaventure, Jacqueline Clavel, Melissa L Bondy, Christopher I Amos, Thanh T Hoang, Michael E Scheurer
Faculty, Staff and Students Publications
Background: Ependymoma is a malignancy of the neuroepithelium-derived ependyma that lines the spinal cord and ventricles of the brain, occurring most frequently in young children and older adults. Genetic susceptibility to ependymoma has proven difficult to assess due to disease rarity.
Methods: We performed genome-wide association studies (GWAS) of 478 ependymoma patients and 4,841 disease-free controls of European ancestry. Ependymoma patients consisted of 117 children (< 18 years old) with whole-genome sequencing (WGS), 142 children with genotyping, and 219 adults (≥18 years old) with genotyping. Genotyped samples were imputed using the 1,000 Genomes Project as the reference panel and underwent quality control filtering. The GWAS was performed separately by age group and technology (genotyped or WGS). GWAS variants were considered significant at P < 5 × 10-8.
Results: Among pediatric subjects with WGS data, we identified a significant intronic variant in EDIL3 (rs149378, P = 1.9 × 10-8) and a nearly significant intronic variant in LHX4 (rs79008224, P = 7.2 …
Training Set Augmentation And Biology-Aware Harmonization Improve Radiomic Models For Lung Cancer Prediction In Indeterminate Nodules, Claire Huchthausen, Menglin Shi, Gabriel De Sousa, James Larner, Einsley Janowski, Jonathan Colen, Krishni Wijesooriya
Training Set Augmentation And Biology-Aware Harmonization Improve Radiomic Models For Lung Cancer Prediction In Indeterminate Nodules, Claire Huchthausen, Menglin Shi, Gabriel De Sousa, James Larner, Einsley Janowski, Jonathan Colen, Krishni Wijesooriya
Data Science Faculty Publications
CT radiomics-based machine learning has potential to predict lung cancer in pulmonary nodules (PNs) earlier than standard-of-care methods. Low malignancy rates in early-development PNs and variable image acquisition hinder development of radiomic models for diagnosing these PNs. To address these challenges, we augmented training using later-development PNs and harmonized for acquisition effects. We examine early-development benign and malignant PNs (n = 106) below the sensitivity of standard-of-care diagnosis. Classifiers predicting malignancy performed near chance when trained on ComBat-harmonized radiomic features from only early-development PNs. We then augmented training with later-development benign and malignant PNs (n = 225). We evaluated whether …
Corporatism For The Informal Economy: Democratising The Potential Of The Mathadi Tripartite Board Model, Shelley Marshall, Hila Shamir, Babu P. Remesh, Anjali Sharma
Corporatism For The Informal Economy: Democratising The Potential Of The Mathadi Tripartite Board Model, Shelley Marshall, Hila Shamir, Babu P. Remesh, Anjali Sharma
Comparative Labor Law & Policy Journal
This article examines the Mathadi Boards in Pune, India, as a pioneering example of corporatist regulation adapted to the informal economy. These tripartite institutions — comprising workers, employers, and the state — negotiate legally binding agreements on wages and working conditions for informal labourers, offering social protections and formalization without relying on traditional employment contracts. Drawing on extensive fieldwork and interviews, the study explores the Boards’ structure, governance, and impact, highlighting their potential as scalable models for informal labour regulation globally. It also identifies challenges related to representation, enforcement, and social exclusion, offering insights into how corporatist frameworks can be …
Co-Curricular Science Experiences Support Undergraduate Students' Science Gpa, Degree Completion, Workforce Entry, And Motivation, Lisa Linnenbrink-Garcia, Tony Perez, Stacy J. Priniski, Sharlyn Ferguson-Johnson, John Keane, Alexandra Lee, Kristy A. Robinson, You-Kyung Lee, Goun Choi, Matthew J. Schell, Danielle N. Berry, Rochelle Schwatz-Bloom
Co-Curricular Science Experiences Support Undergraduate Students' Science Gpa, Degree Completion, Workforce Entry, And Motivation, Lisa Linnenbrink-Garcia, Tony Perez, Stacy J. Priniski, Sharlyn Ferguson-Johnson, John Keane, Alexandra Lee, Kristy A. Robinson, You-Kyung Lee, Goun Choi, Matthew J. Schell, Danielle N. Berry, Rochelle Schwatz-Bloom
STEMPS Faculty Publications
Science co-curricular experiences (SciXP)-such as research experiences and internships-are a common, yet understudied, strategy to enhance undergraduates' science career pursuit. Using a doubly robust method to account for initial differences in science motivation, academic readiness, and career intentions, we investigated whether SciXP participation across four years of college predicted undergraduates' (N = 1984) science achievement, career persistence, and motivation at the end of college and after graduation. Participation in science co-curricular experiences was positively associated with science GPA, earning a science degree, being in a more science-intensive career one to two years post-graduation, and viewing science as important and useful …
Hyena Den Distribution, Human-Hyena Interactions And Mitigation Strategies In The Greater Amboseli Ecosystem, Katherine Elizabeth Davis Matczak
Hyena Den Distribution, Human-Hyena Interactions And Mitigation Strategies In The Greater Amboseli Ecosystem, Katherine Elizabeth Davis Matczak
Honors Theses and Capstones
The Spotted Hyena (Crocuta crocuta) is a prevalent predator across Africa, recognized for their noticeable gait and powerful jaws which enable them to maul and scavenge on prey. Due to human population growth and encroachment onto wildlife territory, the overlap between human settlements and hyena den sites has become a growing concern, particularly regarding livestock predation. Livestock is intrinsic to livelihoods across Africa, with most individuals deriving their livelihoods from pastoralism. This paper provides an evaluation of den proximities to communities, hyena diet preference, human-hyena conflict/attitudes, and mitigation strategies used to protect hyenas, livestock, and the people. Results …
Exploring The Effects Of Voluntary Wheel Running On Inhibitory Control, Ava Prieto
Exploring The Effects Of Voluntary Wheel Running On Inhibitory Control, Ava Prieto
Honors Theses and Capstones
Inhibitory control, a central component of executive function, is the ability to suppress unwanted actions in response to a stimulus (Verbruggen et al., 2014; Verbruggen et al., 2019) and is one of the best indicators of executive task management as well as the ability to prevent unwanted prepotent responses. This capacity is essential for goal specific behavior and for responding flexibly to challenges. The present study examined the effects of voluntary wheel running on inhibitory control in two cohorts of Long-Evans rats using a rodent variant of the canonical stop-signal task. We found that rats with access to an active …
Bias In Nursing Students: How Student Exposure Impacts Patient Interactions, Claire Roy
Bias In Nursing Students: How Student Exposure Impacts Patient Interactions, Claire Roy
Honors Theses and Capstones
Bias is a pervasive issue in healthcare. It affects all aspects of the healthcare system and affects patients primarily through their interactions with healthcare providers. This study aimed to identify if exposure to various patient populations reduced bias among participants and increased their understanding of the way bias impacts patients. Two participants were recruited from a baccalaureate nursing program course titled “Living with Mental Illness” to participate in a series of two-semi structured interviews to identify bias, perceptions of community-based care, and the growth from the beginning to the end of their clinical experiences. Results showed skill development, increased understanding …
After The Impact: Balance Function In Women With Repeated Concussions, Caroline M. Stack
After The Impact: Balance Function In Women With Repeated Concussions, Caroline M. Stack
Honors Theses and Capstones
Balance deficits following repeated mild traumatic brain injuries are well documented, yet research examining the delayed outcomes specifically in college-aged women remains limited. The present study investigated whether women with a history of two or more mTBIs exhibit lasting balance impairments compared to women with zero or one prior mTBI, tested at least six months after their most recent injury. Thirty-four English-speaking women (ages 18-30) recruited from the University of New Hampshire were assigned to a repetitive mTBI group or a control group. Balance was assessed using the Balance Error Scoring System and a MetaMotion inertial measurement sensor positioned on …
Mindfulness Matters: Reducing Anxiety In Prelicensure Undergraduate Nursing Students Using Virtual Reality Meditation Prior To High Fidelity Simulation., Lindsey K. Hildreth
Mindfulness Matters: Reducing Anxiety In Prelicensure Undergraduate Nursing Students Using Virtual Reality Meditation Prior To High Fidelity Simulation., Lindsey K. Hildreth
Honors Theses and Capstones
Abstract:
The aim of this study was to evaluate the effectiveness of a 5-minute virtual reality (VR) meditation intervention in reducing self-reported anxiety among prelicensure nursing students immediately prior to their participation in a high-fidelity clinical simulation. Anxiety levels were measured using a Visual Analog Scale (VAS) and compared between students who participated in the VR meditation intervention and those in a control group receiving standard prebrief, and no VR meditation. It was hypothesized that students who engage in VR meditation would demonstrate a reduction in anxiety compared to students in the control group.
Improving Low Fresh Gas Flow Adherence To Lower Co2e Emissions, Luke Charles Ricci
Improving Low Fresh Gas Flow Adherence To Lower Co2e Emissions, Luke Charles Ricci
Honors Theses and Capstones
Volatile anesthetic gases contribute significantly to healthcare-related greenhouse gas emissions. These greenhouse gas emissions can be increased due to higher fresh gas flows. At Dartmouth-Hitchcock Medical Center (DHMC), open and semi-open systems with fresh gas flow (FGF) rates above two liters per minute result in anesthetic gas waste. Literature suggests multifaceted quality improvement interventions are effective in improving low fresh gas flow adherence in anesthesia provider practices. The purpose of this study was to evaluate the potential reduction in anesthetic gas waste and carbon dioxide equivalent (CO₂e) emissions at Dartmouth-Hitchcock Medical Center through improved adherence to low fresh gas flow …
Exploring The Association Between Internal Body Temperature And Metabolic Status In Early Lactation Jersey Cattle, Alexandra Ferreri, Claira Seely
Exploring The Association Between Internal Body Temperature And Metabolic Status In Early Lactation Jersey Cattle, Alexandra Ferreri, Claira Seely
Honors Theses and Capstones
No abstract provided.
Does The Impact Of Volunteering On Health Differ By Wealth? [Research In Brief: Volunteering], Seoyoun Kim, Cal J. Halvorsen
Does The Impact Of Volunteering On Health Differ By Wealth? [Research In Brief: Volunteering], Seoyoun Kim, Cal J. Halvorsen
Harvey A. Friedman Center for Aging
Volunteering among older adults has many potential health benefits; however, older adults with more wealth are also more likely to volunteer in the first place, raising the question of whether they are the ones reaping the most benefits. This study asked two questions: (1) Does formal volunteering improve self-reported health and reduce depressive symptoms in older adults? (2) Does the impact of volunteering on these outcomes differ between older adults in the lowest and highest wealth quintiles?
An Exploratory Study In Sports Geography: The Interaction With The Environment And Sense Of Place In Endurance Running Events, Jackson Steffener
An Exploratory Study In Sports Geography: The Interaction With The Environment And Sense Of Place In Endurance Running Events, Jackson Steffener
Dissertations and Theses @ UNI
This study examines how endurance running shapes runners' sense of place through interactions with physical environments, social dynamics, and embodied experience. With sports geography, it explores how participants form emotional and spatial connections to race settings while moving through varied landscapes under physical strain. A phenomenological multi-site case study design was used, focusing on four endurance events in Iowa that differed in terrain, setting, and structure.
Data were collected from 46 participants using mental mapping and semi structured field notes. Mental maps identified meaningful locations along race courses, while field notes captured emotional responses, environmental conditions, and social interactions. Thematic …
Reflections On Linear B (Part 13): Sign 21 May Derive From The Ancient Egyptian 'Wedjat Eye’ (‘Eye Of Horus’ But Also Associated With Ra), Gerald Leonard Cohen
Reflections On Linear B (Part 13): Sign 21 May Derive From The Ancient Egyptian 'Wedjat Eye’ (‘Eye Of Horus’ But Also Associated With Ra), Gerald Leonard Cohen
Arts, Languages and Philosophy Faculty Research & Creative Works
This article suggests that Linear B sign 21 (of unknown origin)
may derive ultimately from the Ancient Egyptian ‘wedjat eye’
(Eye of Horus). A point of special interest here is the possibility
that the pronunciation of Linear B sign 21 (designated as ‘qi’)
derives in abbreviated form from the Proto-Indo-European dual
of ‘eye’ and would therefore be the oldest Greek attestation of
that reconstructed PIE form.
Stall Detection In Hydraulic Excavator Operations Using Heuristics And Machine Learning: A Case Study, Mateo Fernando Montenegro Defaz, Kwame Awuah-Offei, Yixiang Gao
Stall Detection In Hydraulic Excavator Operations Using Heuristics And Machine Learning: A Case Study, Mateo Fernando Montenegro Defaz, Kwame Awuah-Offei, Yixiang Gao
Mining Engineering Faculty Research & Creative Works
This work aims to develop a reliable algorithm for stall detection during excavator digging by analyzing key operational variables such as velocity and angular displacements from machine monitoring data. The work develops and validates a heuristic algorithm to detect stalling events and trains a support vector machine classification algorithm to distinguish between "normal" digging cycles and cycles with stalling. This work is a novel attempt at using a classification algorithm to categorize digging cycles into normal and those with stalling events based on machine monitoring data alone. The developed classification algorithm achieved a sensitivity of 100%, indicating it correctly identified …
Analysis Of Pull-Out Tests For Resin-Grouted Rib Bolts, Khaled Mohamed, Yuting Xue, Dogukan Guner, Alper Kirmaci, Taghi Sherizadeh
Analysis Of Pull-Out Tests For Resin-Grouted Rib Bolts, Khaled Mohamed, Yuting Xue, Dogukan Guner, Alper Kirmaci, Taghi Sherizadeh
Mining Engineering Faculty Research & Creative Works
Resin-grouted rib bolts serve as a crucial means of stabilizing spalling of coal ribs in underground coal mines. A comprehensive investigation into their efficacy was undertaken by a collaborative effort between the National Institute for Occupational Safety and Health (NIOSH) and Missouri University of Science and Technology (MST). This study involved pull-out tests of rib bolts in multiple locations, including six coal mines and the NIOSH research mine. A total of seventy-three (73) pull-out tests were conducted for rib bolts installed at different rotation speeds and a wide range of anchorage lengths, ranging from a short encapsulation length of 0.305 …