Digital Commons Network^™

Un-African Union Cooperation In Darfur: Multilevel Governance In Action And The Future Of International-Regional Peace Operations, Philip Mutio

The Journal of Social Encounters

This paper will explore the changing dynamics between global and regional governance frameworks using the example of the UN partnership with regional and sub-regional organizations in the management of intricate peace and security issues. The analysis is anchored on the case of African Union–United Nations Hybrid Operation in Darfur (UNAMID), an example of layered governance, to examine the effect of coordination problems, operational difficulties, and joint mission performance in the areas of peace talks, post-conflict reconstruction, and civilian protection. Along with persistent issues including scarce resources, political instability, and disjointed command structures, the report acknowledges significant advancements such as increased …

Preventive Interventions Targeting Social Determinants Of Health: Implications For Healthcare Utilization And Cost, Audrey Wrinkle

NEXUS: The Liberty Journal of Interdisciplinary Studies

Preventive interventions targeting social determinants of health could reduce avoidable healthcare utilization and positively impact long-term cost outcomes within healthcare systems. Evidence indicates that financial and social barriers to preventive care lead to delayed treatment and increased use of high-cost healthcare services in the long term. Preventive interventions focusing on upstream social factors, like home-based care and digital health programs, could improve patient outcomes and reduce avoidable service utilization. Also, incorporating social needs data into policy creation could promote better allocation of healthcare resources. This research highlights the role of prevention-focused strategies in promoting cost-effective, sustainable healthcare delivery.

Le Défi Mondial : Panorama Comparatif Des Soins Néonatals Au Maroc Et Aux États‑Unis, Manasi Joshi

NEXUS: The Liberty Journal of Interdisciplinary Studies

Cette étude comparative examine les soins néonatals au Maroc et aux États-Unis après un stage dans une clinique privée à Rabat. Bien que les pratiques médicales principales soient universelles, leur application varie dans différents pays selon les circonstances socio-économiques et culturelles. Basée sur des observations directes, des entretiens avec des professionnels de soins néonatals marocains et une analyse de la littérature sur ce sujet dans ces deux pays, cette recherche discute de quatre différences principales : la disponibilité des ressources, l’accès aux soins de qualité, l’influence culturelle et les obstacles financiers. Malgré la pénurie évidente de personnel dans les hôpitaux, …

Hierarchical Context Caching Using Data Segmentation And Predictive Aggregation, Sarita A. Joshi, Leo J. Gustas, Blane C. Clark

Defensive Publications Series

Standard context caching for large language models can be inefficient in workflows with large, multi-part contexts, such as clinical documentation, where streaming data can invalidate static records and individual records may not meet caching thresholds. A computer-implemented system and method for optimizing context caching are described. The system may utilize a hierarchical structure that segments input context into static, semi-static, and dynamic layers based on update frequency. The system may also proactively aggregate historical records from multiple patients into a single cache prefix to meet service provider token minimums. This approach of hierarchical segmentation and predictive aggregation can reduce cache …

Forecasting Demand At Physical Facilities Using Diverse Heterogeneous Real-World Data, Kapil Parakh, Daniel Klein

Defensive Publications Series

Unpredictable fluctuations in customer demand at physical facilities can have substantial operational impacts. Current demand forecasting approaches tend to be simplistic and reactive as they rely primarily on internal historical data, which provides inadequate accuracy to support future resource allocation. This disclosure describes techniques to provide accurate medium-term demand forecasts for physical operational facilities by synthesizing a diverse set of relevant real-world factors obtained from a fusion of numerous heterogeneous data sources related to human practices and needs. The factors can be continually aggregated and input to a suitably trained machine learning model trained to generate specific actionable output designed …

Cable Coiling Detection Using Coupling-Based Sensing, Hp Inc

Defensive Publications Series

A smart cable monitoring system detects cable coiling conditions before cable degradation occurs. The system utilizes dedicated sensing conductors integrated within the cable to monitor changes in coupling characteristics caused by cable geometry variations. By comparing the measured sensing signature against a baseline condition, the system can identify prolonged coiled states and provide user feedback or preventive actions. Thermal sensing may also be incorporated to improve detection robustness and support cable health assessment.

Imsa Summer Symposium 2026, Student Inquiry And Research (Sir)

Summer Symposium

For nearly four decades, IMSA has worked to advance the human condition through educational innovation. The Summer Symposium is our annual showcase for the research projects that were conducted in IMSA’s experiential learning programs between May and August. These programs include Student Inquiry and Research (SIR), IN2 Business Internships, and the Student Research and Experiential Learning Opportunity (SRELO) program. For the first time, we are also excited to welcome IMSA Research, Inquiry Skills, and Experimentation (RISE) students to present at the Summer Symposium.

Cover Design

Luke Berryman

Ppt-1 Regulates Lipid Droplet Homeostasis And Promotes Oxidative-Stress Resilience In C. Elegans., Chukwuadinula Deborah Ashiedu

Master’s Theses and Projects

No abstract provided.

Differential Effects Of Thiamine, Bap, And Thidiazuron Combinations On Shoot Multiplication And Phenolic-Flavonoid Accumulation In Pineapple In Vitro Cultures, Dinda Septia Rachman, Erni Suminar, Anne Nuraini, Fiky Yulianto Wicaksono, Suseno Amien, Syariful Mubarok, Hermanto

Jurnal Kultivasi

The demand for high-quality pineapple (Ananas comosus (L.) Merr.) planting materials continues to increase, while conventional propagation methods are limited in multiplication rate, uniformity, and production efficiency. In vitro culture offers an alternative approach for rapid and large-scale seedling production. However, information on the effects of thiamine and cytokinin combinations on both shoot multiplication and phenolic-flavonoid accumulation in pineapple in vitro remains limited. This study evaluated ten defined combinations of thiamine and cytokinin for shoot multiplication and total phenolic-flavonoid contents of pineapple explants. The experiment employed a completely randomized design with 10 treatment combinations of thiamine (0.1 and 0.4 mg/L), …

Enhancing Tea Productivity Through Integrated Fertilization And Pruning Management: A Review, Intan Ratna Dewi Anjarsari, Murgayanti, Muhamad Kadapi, Syariful Mubarok, Uum Umiyati, Salsabilah, Alifatul Azmi, Afifah Putri Ramadhan, Trifani Hana Husniah, Rosita, Azkal Azkiya

Jurnal Kultivasi

Tea productivity is strongly influenced by agronomic management practices, particularly fertilization and pruning, which play critical roles in regulating plant growth, physiological performance, and shoot regeneration. This review aims to synthesize current scientific evidence on how integrated fertilization and pruning management can sustainably enhance tea productivity. A narrative review approach was employed by collecting and analyzing peer-reviewed articles published between 2015 and 2025 from reputable databases, including Google Scholar and major international journals. The review highlights that balanced fertilization strategies, combining inorganic, organic, and biofertilizers, significantly improve nutrient availability, photosynthetic efficiency, and shoot yield. Pruning, when properly timed and executed, …

The Effects Of Melatonin And Potassium Fertilizer On Fruit Yield And Quality Of ‘Haruhi’ Strawberry Under Two Light Conditions, Ghaida Marsha Nurizqia, Farida, Reginawanti Hindersah, Kenji Endo, Rahmat Budiarto, Syariful Mubarok

Jurnal Kultivasi

Strawberry (Fragaria × ananassa) ‘Haruhi’ is a subtropical plant that is being cultivated in Indonesia. High temperatures in tropical climates could decrease strawberry yield and fruit quality. The purpose of this study was to evaluate the effect of light, melatonin, potassium fertilizers, and their interactions on the yield and fruit quality of ‘Haruhi’ strawberry. This research was conducted from April to June 2024 at the Bale Tatanen, Faculty of Agriculture, Universitas Padjadjaran. A split-plot design was used, with lighting treatment as the main plot and melatonin and potassium fertilizer treatments as the subplot. Lighting treatments consisted of supplemental LED lighting …

The Effectiveness Of Bacillus-Coated Npk Fertilizer On Broccoli Growth, Nutrient Status, Rhizosphere Bacillus Population, Yield, And Flower Quality, Betty Natalie Fitriatin, Rara Rahmatika Risanti, Reginawanti Hindersah, Fasa Aditya Hanindipto, Gita Bina Nugraha

Jurnal Kultivasi

Efforts to increase the availability of macronutrients in soil have relied on inorganic fertilization, particularly NPK fertilizers. However, global challenges in the fertilizer raw material supply chain, including price fluctuations and availability, are driving the need for more efficient and sustainable fertilizer alternatives. The field experiment was conducted in Baruajak, Lembang District, West Java, Indonesia, to evaluate the effectiveness of Bacillus-coated NPK fertilizer on broccoli (Brassica oleracea var. italica) growth, nutrient status, rhizosphere Bacillus population, yield, and flower quality. The experiment used a randomized complete block design with 15 fertilizer treatments and three replications. Treatments consisted of two coated NPK …

Leadership And Character In The Law: An Introduction From Kenneth Townsend, Kenneth Townsend

Journal of Legal Education

No abstract provided.

Fostering Future Difference-Makers: The Integration Of Leadership Training In Law Schools, Leah Teague

Journal of Legal Education

No abstract provided.

Obeying In Advance Will Not Save You: How Adaptive Leadership Can Help Legal Education Stay Mission Driven In Times Of Authoritarianism And Fear, Tania Luma

Journal of Legal Education

No abstract provided.

What Do We Do At The End Of A World?: Cultivating Emergent Leadership In A Time Of Collapse, Brent Godfrey

Journal of Legal Education

No abstract provided.

Professional Identity Formation As Theory And As Practice For The Education Of A Lawyer, Louis D. Bilionis, Neil W. Hamilton

Journal of Legal Education

No abstract provided.

Who’S The Lawyer Now? Professional Identity In A Genai World, Aric K. Short

Journal of Legal Education

No abstract provided.

Practicing Pietas: Character Development For Lawyers As Citizens, Elisabeth Rain Kincaid

Journal of Legal Education

No abstract provided.

Moral Virtues, Professional Identity, And Leadership, Timothy W. Floyd

Journal of Legal Education

No abstract provided.

The Large Impact Of Small Groups On The Character-Based Leadership Development Of Law Students, Benjamin Rigney, Janice Craft

Journal of Legal Education

No abstract provided.

Book Review Of The Lawyer Nation: The Past, Present, And Future Of The American Legal Profession, Jennifer A. Gundlach

Journal of Legal Education

No abstract provided.

Profiling Arbutin As A Potent Cholinesterase And Gsk-3Β Inhibitor And Evaluating Its Cytotoxicity In Sh-Sy5y Cells For Alzheimer’S Disease Therapy, Shirin Tarbiat, Tuğba Bal, Deni̇z Gülmez

Turkish Journal of Biology

Background/aim: Alzheimer’s disease (AD) is a neurodegenerative disorder linked to cognitive decline and memory loss, marked by hyperphosphorylated tau tangles and decreased acetylcholine levels, which are affected by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity. Glycogen synthase kinase-3 beta (GSK-3β) also plays a role in AD through abnormal activation. In this study, the potential of β-arbutin to inhibit cholinesterases and GSK-3β was investigated, utilizing in vitro assays, cytotoxicity analysis, and molecular docking simulations to explore its therapeutic implications.

Materials and methods: Ellman’s technique was used to test the inhibitory effects of arbutin on cholinesterase enzymes. An ATP-Glo luminescent assay kit was …

Probiotic Intervention In Colorectal Cancer: The Cytotoxic And Apoptotic Potential Of Lactobacillus Cell-Free Supernatants, Bahar Yilmaz, Berna Erdal

Turkish Journal of Biology

Background/aim: Failures in the treatment of colorectal cancer (CRC) have increased scientific interest in the potential of the bioactive compounds contained in cell-free supernatants (CFSs) obtained from probiotic bacteria for cancer treatment. The aim in this study was to investigate the effects of CFSs obtained from Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus) and Lactobacillus paracasei subsp. paracasei (L. paracasei) on colorectal cancer cell lines (HT-29 and Caco-2) and a healthy colon epithelial cell line (CCD841 CoN).

Materials and methods: Cytotoxic effects on the cell lines were determined by MTT assay. In line with the IC50 values obtained, morphological changes were …

Cover And Contents

Turkish Journal of Biology

No abstract provided.

Antiatopic Dermatitis Activity Of Lissachatina Fulica Mucin: Network Pharmacology Analysis And Experimental Validation, Atin Supiyani, Wasmen Manalu, Lina Noviyanti Sutardi, Mawar Subangkit, Andriyanto Andriyanto

Turkish Journal of Biology

Background/aim: Lissachatina fulica mucin (LFM) has been used as a nutraceutical, therapeutic agent, and cosmetic ingredient. The bioactivity of mucin depends on bioactive compounds whose composition is strongly influenced by the snail’s diet. This study investigated the bioactive compounds in L. fulica mucin as potential therapeutic agents for atopic dermatitis (AD).

Materials and methods: LFM was collected from snails fed long beans and melon rinds for 4 weeks, freeze-dried, and analyzed using liquid chromatography–mass spectrometry followed by network pharmacology (NP) analysis to identify its bioactive compounds. A total of 60 BALB/c mice were sensitized on the dorsal skin with 1% …

The N-Terminal, Wd40, And C-Terminal Domains Of Wdr-31 Control Ciliary Localization And Cooperate With Elmod/Rp2 Gaps To Maintain Membrane Compartmentalization, Sebi̇ha Çevi̇k, Fatma Güzel

Turkish Journal of Biology

Background/aim: WD40 repeats are found in many ciliary proteins. Although the WD40 repeat-containing WD repeat-containing protein 31 (WDR-31) is known to regulate ciliary protein trafficking and morphology, the specific contributions of its N-terminal, WD40, and C-terminal domains to protein localization and ciliary gate integrity remain unclear. Aim of this study is to dissect the functional roles of WDR-31 domains by investigating their contributions to ciliary localization, ciliary protein trafficking, and gate integrity.

Materials and methods: Using CRISPR/Cas9 technology, we generated Caenorhabditis elegans strains with in-frame deletions that removed the N-terminus (WDR-31(ΔN)), WD40 (WDR-31(ΔWD)), and C-terminus (WDR-31(ΔC)). We next examined the …

Discovery And Functional Characterization Of Novel Programmed Death-Ligand 1 Monoclonal Antibodies, Nurşah Ersezen, Mai̇de Şeker, Arzu Aysan, Durmuş Akdoğan, Mehmet Ender Avci, Asli Kurden Pekmezci̇, Si̇bel Kalyoncu Uzunlar, Mehmet İnan, Tamer Yağci

Turkish Journal of Biology

Background/aim: Targeted therapies with monoclonal antibodies provide cancer patients with better prognosis and diseasefree survival. The blockade of immune checkpoints, including programmed cell death protein-1 (PD-1) and its ligand PD-L1, with monoclonal antibodies may boost immune responses against tumors and is regarded as an effective strategy in cancer immunotherapy. We describe the generation of anti-PD-L1 monoclonal antibodies with high affinity and specificity, and we assess their potential for therapeutic use in cancer.

Materials and methods: Hybridomas were selected for PD-L1 specificity and cross-reactivity with other immune checkpoint proteins and PD-L1 orthologs using indirect ELISA. Immunofluorescence and Western blotting assays were …

Synthesis, Utilization And Biological Evaluation Of Β-Hairpin Peptides As Inhibitors Of Immune Checkpoints, Sarah Naylon

Electronic Theses and Dissertations 2020 - Present

Peptide therapeutics have emerged as promising alternatives to monoclonal antibodies because of their smaller size, improved tissue penetration, and synthetic versatility. Yet their broader application is often limited by poor structural stability, rapid clearance, and reduced target residence times. This dissertation describes the design, synthesis, structural characterization, and biological evaluation of β-hairpin peptides as inhibitors of immune checkpoints and as peptide vaccine scaffolds while developing strategies to overcome these limitations. At first a series of antibody-derived β-hairpin peptides (mimics of complementary determining region heavy-chain 3: CDR-H3s) as covalent inhibitors of the PD-1/PD-L1 immune checkpoint were investigated. Electrophilic warheads were incorporated …

The Hidden Costs Of Accountability: Unpacking The Emotional Labor Of Student Conduct Work And Building Tools For Resilience, Tiffany Marlene Shierling

Graduate Student Dissertations, Theses, Capstones, and Portfolios

This dissertation explored the psychological challenges student conduct administrators (SCAs) face in higher education. These professionals have encountered significant emotional labor, vicarious trauma, and ethical dilemmas as they address student misconduct while striving to achieve educational and developmental outcomes. The study highlighted a research gap concerning the impact of these challenges on the mental well-being of SCAs, which hinders the development of effective support systems. This study aimed to address the mental health needs of SCAs by developing a comprehensive toolkit. Grounded in self-compassion theory and resilience theory, the toolkit provides resources for emotional self-regulation, supervisor training, and institutional recommendations.