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Articles 38941 - 38970 of 1791776
Full-Text Articles in Entire DC Network
Effect Of Therapeutic Ultrasound Versus Anti-Inflammatory Drugs In The Treatment Of Trigger Finger. A Placebo Randomized-Controlled Trial., Eslam Elsayed Ali Shohda
Effect Of Therapeutic Ultrasound Versus Anti-Inflammatory Drugs In The Treatment Of Trigger Finger. A Placebo Randomized-Controlled Trial., Eslam Elsayed Ali Shohda
Journal of Medicine in Scientific Research
Background: Trigger finger (TF) is a painful disorder that hinders the use of the entire hand. One of the most widely used modalities in the field of physiotherapy is therapeutic ultrasound (US); however, no randomized control trial has investigated the use of US in the treatment of TF. The objective of this trail is to determine the effect of therapeutic US on pain intensity and the frequency of daily finger clicking in patients with TF. Materials and Methods: A single-blind, randomized (1:1), placebo-controlled, clinical trial was conducted at a physiotherapy outpatient clinic at Alahrar Teaching Hospital in Zagazig, Egypt. Twenty …
Casey Holland, Casey Holland, Olivia Kelly
Casey Holland, Casey Holland, Olivia Kelly
Oral Histories of Farming along the Middle Rio Grande
No abstract provided.
Predictors Of Mortality Among Under-Five Children Hospitalized With Severe Community-Acquired Pneumonia. A Retrospective Observational Study, Marwa Taha
Journal of Medicine in Scientific Research
Background Severe community-acquired pneumonia (SCAP) remains a critical public health issue and a leading cause of childhood mortality and morbidity, especially in developing countries. Identifying predictors of death in children with SCAP and early recognition of high-risk patients could significantly improve survival rates. Objective This study aims to identify possible predictors of mortality in pediatric SCAP, facilitating the early recognition of high-risk children. Patients and Methods This retrospective observational study included 120 children under the age of five who were admitted with SCAP, based on World Health Organization (WHO) guidelines. Demographic data, clinical characteristics, laboratory findings, and hospital outcomes were …
Knowledge And Practice Of Breast Self-Examination Among Young Women Comes To General Surgery Clinic In Shebin El Kom Teaching Hospital, Shimaa M W Kalama
Knowledge And Practice Of Breast Self-Examination Among Young Women Comes To General Surgery Clinic In Shebin El Kom Teaching Hospital, Shimaa M W Kalama
Journal of Medicine in Scientific Research
Background Breast cancer, which makes up 30.4% of newly diagnosed tumors, is one of the most common cancers among young girls. Every woman who is 20 years of age or older is thought to be at risk of getting breast cancer. This research is crosssectional. The Shebin-Elkom Teaching Hospital served as the study's site. Randomized sampling was used to enroll five hundred women for this study. To collect information, a self-administration questionnaire was employed. Objective:. to evaluate the women who visited the surgery clinic at Shebin El Kom Teaching Hospital's knowledge of breast cancer, BSE, and its function in early …
Influence Of Frailty On The Outcome Of Surgical Patients Over 70 Years Old With Admission Criteria In The Icu At Shebin El-Kom Teaching Hospital, Talal Ibrahim Mostafa Hagag Dr, Shimaa Mohamed Kalama
Influence Of Frailty On The Outcome Of Surgical Patients Over 70 Years Old With Admission Criteria In The Icu At Shebin El-Kom Teaching Hospital, Talal Ibrahim Mostafa Hagag Dr, Shimaa Mohamed Kalama
Journal of Medicine in Scientific Research
Background: In older adults, frailty is a complex condition marked by diminished functional reserves and heightened susceptibility to stressors. It is a more accurate predictor of unfavorable postoperative outcomes in the context of surgical operations than a patient's age or preexisting medical problems. Objectives: This study aimed to investigate the effects of frailty, as assessed by the Clinical Frailty Scale (CFS) and the 5-item Modified Frailty Index (MFI-5), on important clinical outcomes, including length of stay in the intensive care unit (ICU), hospitalization mortality, and the chance of readmission within 30 days, in older adults undergoing major abdominal surgeries. Methods: …
Ct Chest Findings And Laboratory Investigations Of Covid 19 Patients And Their Relation To The Clinical Outcome, Zeinab Moustafa Moustafa Metwalli, Mohammed Emadeldeen, Heba Abdelaziz, Nagwa M. Salah
Ct Chest Findings And Laboratory Investigations Of Covid 19 Patients And Their Relation To The Clinical Outcome, Zeinab Moustafa Moustafa Metwalli, Mohammed Emadeldeen, Heba Abdelaziz, Nagwa M. Salah
Journal of Medicine in Scientific Research
For both the initial evaluation and follow-up in suspected COVID-19 cases, chest CT is strongly recommended. Additionally, the disease and its severity might be suspected using basic laboratory investigations. Better clinical results and appropriate management may result from all of this. Aim to evaluate the relation between the clinical outcome of COVID-19 patients, laboratory data, and the severity of CT chest findings. Methods 90 individuals who were referred to the radiodiagnosis department from the National Hepatology and Tropical Medicine Research Institute's Internal Medicine Department after PCR confirmed that they had COVID-19 were included in this retrospective study. Each patient was …
Outcomes Of Endoscopic Third Ventriculostomy (Etv) In Hydrocephalus Secondary To Aqueductal Stenosis After Age Of Anterior Fontanel Closure, Mohammad Abdulsalam Soliman, Eslam Abozeid Kandil, Mahmoud Moustafa Taha, Hassan Ahmed Abaza
Outcomes Of Endoscopic Third Ventriculostomy (Etv) In Hydrocephalus Secondary To Aqueductal Stenosis After Age Of Anterior Fontanel Closure, Mohammad Abdulsalam Soliman, Eslam Abozeid Kandil, Mahmoud Moustafa Taha, Hassan Ahmed Abaza
Journal of Medicine in Scientific Research
Background: Non-communicated hydrocephalus secondary to aqueductal stenosis is common, for which endoscopic third ventriculostomy (ETV) has emerged as an effective surgical management. Objective: To evaluate the clinical outcomes of ETV in patients with obstructive hydrocephalus due to aqueductal stenosis in patients over 2 years of age. Methods: This retrospective study was conducted at our institution and included 57 patients older than 2 years who underwent ETV between 2017 and 2024. Demographic data, clinical presentation, and follow-up outcomes were analysed. ETV was considered successful if the patient remained shunt-free during the follow-up period. Results: The mean age was 22.8 ± 10.5 …
Investigating The Prevalence Of Astigmatism In Patients With Intermittent Exotropia In Egyptian Children, Zeinab A Saad, Ghada Samir, Osama M. Abdelhay, Mohamed Gaber Abdallah
Investigating The Prevalence Of Astigmatism In Patients With Intermittent Exotropia In Egyptian Children, Zeinab A Saad, Ghada Samir, Osama M. Abdelhay, Mohamed Gaber Abdallah
Journal of Medicine in Scientific Research
Uncorrected refraction is the major cause of visual morbidity among children and can result in the development of strabismus. Although several studies have investigated the risk factors for intermittent exotropia, uncorrected astigmatism, which is critical for prevention and treatment, has not been well estimated. Objectives: To evaluate the association between uncorrected astigmatism and intermittent exotropia in children. Methods: This retrospective, analytical, cross-sectional, population-based study included 90 children with intermittent exotropia X(T) who were followed up for two years; the children were aged from 6 to 12 years old. Patients were retrospectively reviewed to determine the prevalence of astigmatism and amblyopia …
Breast Cancer Therapy Induced Right Ventricular Cardiomyopathy: A Single Institute Experience, Doaa M Elsayed, Safa Ahmed Balata, Mohamed Elsayed Saleh
Breast Cancer Therapy Induced Right Ventricular Cardiomyopathy: A Single Institute Experience, Doaa M Elsayed, Safa Ahmed Balata, Mohamed Elsayed Saleh
Journal of Medicine in Scientific Research
Background It is well-known that chemotherapy medicines can cause cardiomyopathy and left ventricular dysfunction as adverse effects. There is scant evidence concerning the effects of chemotherapeutic drugs on the integrity & functionality of the right ventricle (RV). Aim To study the impact of cardiotoxic systemic therapy on right ventricular function in nonmetastatic breast cancer cases, particularly evaluating the efficacy of modern echocardiographic procedures for the early recognition of RV cardiomyopathy. Patient and Method A total of 104 women diagnosed with breast cancer participated in this prospective trial. Two therapy groups were established for the cases: 42 patients received anthracycline therapy, …
Exploring The Relationship Between Phonological Awareness And Adhd Symptoms In School-Aged Children, Nihal Hisham Abdelhamid, Mona Abdel-Fattah Hegazi, Dina Ahmed Elsayed Elrefaie
Exploring The Relationship Between Phonological Awareness And Adhd Symptoms In School-Aged Children, Nihal Hisham Abdelhamid, Mona Abdel-Fattah Hegazi, Dina Ahmed Elsayed Elrefaie
Journal of Medicine in Scientific Research
Attention deficit hyperactivity disorder is one of the neurodevelopmental disorders which characterized by: inattention and impulsivity as well as apparent deficits in executive functioning and impulse control. Auditory-linguistic areas and primary reading skills as early literacy skills were found to be lower than normal in ADHD. Other researches considered that the reading difficulties are in the areas of fluency, comprehension, and sustained attention during reading tasks. The aim of the study is to evaluate the phonological awareness abilities skills in children with attention deficit hyperactive disorder (ADHD), being contributors for early reading acquisition. Phonological awareness (PA) is the precise recognition …
Perioperative Dexmedetomidine Improve Outcomes After Cabg Surgery., Reham Salah, Ismail Rafik Barada, Mazen Isam Eldein Ali
Perioperative Dexmedetomidine Improve Outcomes After Cabg Surgery., Reham Salah, Ismail Rafik Barada, Mazen Isam Eldein Ali
Journal of Medicine in Scientific Research
Background Dexmedetomidine, is used in cardiac surgeries for its sedation, anxiolysis, and analgesic properties, with minimal respiratory depression. It may improve clinical outcomes in CABG surgery by reducing inflammatory responses, providing neuroprotection, and enhancing hemodynamic stability. Aim To assess the efficacy and safety of perioperative dexmedetomidine in improving clinical outcomes in CABG surgery. Methods This prospective, randomized controlled trial involved 160 patients undergoing elective on-pump CABG surgery. Participants were divided into two groups: 80 received dexmedetomidine, and 80 received a placebo. Key outcomes measured included the incidence of postoperative complications, duration of mechanical ventilation, and ICU stay. Results The dexmedetomidine …
Pediatric Cardiac Surgery After Pulmonary Arterial Interventions: Short-Term Outcomes, Rania Abushokka, Hanan Mohammed Hassan, Rasha Hosni, Amal Younan, Ahmed Algebaly
Pediatric Cardiac Surgery After Pulmonary Arterial Interventions: Short-Term Outcomes, Rania Abushokka, Hanan Mohammed Hassan, Rasha Hosni, Amal Younan, Ahmed Algebaly
Journal of Medicine in Scientific Research
Background: Congenital cardiac interventions are progressing at a rapid pace. In the last few years, techniques such as stent placement for pulmonary artery stenosis, right ventricle outflow tract and ductal stenting showed great advances. Surgery over stents are increasing in complexity. Left pulmonary artery and right ventricle outflow tract sites account for more than half of stent handling. Percutaneous devices are not an ‘‘enemy’’ for the surgeon, but a tool for continuing the development of our surgical strategies. In this study, we describe the short-term outcome of patients who underwent surgical repair after pulmonary interventions for congenital heart diseases at …
Frequency Of Autoimmune Primary Adrenal Insufficiency In Children And Adolescents With Type 1 Diabetes Mellitus, Randa Mohamed Darwish, Ayat Ibrahim Ghanem, Lamis Safwat Mubarak
Frequency Of Autoimmune Primary Adrenal Insufficiency In Children And Adolescents With Type 1 Diabetes Mellitus, Randa Mohamed Darwish, Ayat Ibrahim Ghanem, Lamis Safwat Mubarak
Journal of Medicine in Scientific Research
Background Type 1 diabetes mellitus (T1DM) is a chronic endocrine disorder of autoimmune origin with a predisposition to the development of further autoimmune diseases, including autoimmune adrenal insufficiency (Addison’s disease). Although uncommon and frequently underdiagnosed, it can coexist with T1DM, causing life-threatening complications if undiagnosed. Aim To assess the frequency of autoimmune adrenal insufficiency in children with T1DM and its association with other autoimmune diseases. Methods A cross-sectional study was conducted on 110 children with type 1 diabetes mellitus (T1DM) and 100 age- and sex-matched healthy controls. All participants underwent a full clinical evaluation and laboratory testing, including serum cortisol, …
Evaluating The Efficacy Of Conventional Crystalloid Cardioplegia Versus Modified Del Nido Cardioplegia In Patients With Multivessel Coronary Artery Disease For Cabg Surgery, Reham Salah, Ismail Rafik Barada, Mazen Isam Eldein Ali
Evaluating The Efficacy Of Conventional Crystalloid Cardioplegia Versus Modified Del Nido Cardioplegia In Patients With Multivessel Coronary Artery Disease For Cabg Surgery, Reham Salah, Ismail Rafik Barada, Mazen Isam Eldein Ali
Journal of Medicine in Scientific Research
Background: Cardioplegia is crucial in cardiac surgery for myocardial protection. Modified del Nido cardioplegia, initially used in paediatric patients, is now employed in adult cardiac surgeries for its prolonged protection with a single dose. Aim: To compare the efficacy of conventional crystalloid cardioplegia and modified del Nido cardioplegia in patients undergoing coronary artery bypass graft surgery (CABG) for multivessel coronary artery disease (CAD). Methods: A randomized controlled trial included 94 adult patients undergoing elective CABG. Patients were randomly assigned to receive either conventional crystalloid cardioplegia or modified Del Nido cardioplegia. Data collected included CPB and cross-clamp times, cardioplegia volume, postoperative …
Fish In An Aquaponics System, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Fish In An Aquaponics System, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Supplementary Content for Aquaponics: Farming Fish and Growing Greens for Grades 9–12
This PowerPoint slide provides readers with information on fish in an aquaponics system. This book was published by the Purdue University Press. Copyright 2026.
Permission: Illinois-Indiana Sea Grant
Usc 462 West 141 Llc V. Richards
Usc 462 West 141 Llc V. Richards
All Decisions
In this nonpayment proceeding, the tenant moved for summary judgment, asserting the landlord was precluded from collecting rent under Multiple Dwelling Law (MDL) § 302(1)(b) because the building was occupied contrary to its certificate of occupancy. The court granted the tenant's motion, taking judicial notice of HPD and OATH/ECB violations indicating unlawful combining of rooming units. The court confirmed that such violations prevent rent recovery and nonpayment proceedings for any unit, regardless of whether the unlawful occupancy directly relates to the tenant's apartment. The court also held that the MDL § 302 defense is not waivable and dismissed the landlord's …
Effectiveness Of Myoinositol Versus Metformin As Adjuvant Treatment On Infertile Pcos Women Undergoing Ovulation Induction Cycles Prospective Cohort Study, Ahmed M. Salman, Fatma M. Sayed, Hesham Mohammed Hamad
Effectiveness Of Myoinositol Versus Metformin As Adjuvant Treatment On Infertile Pcos Women Undergoing Ovulation Induction Cycles Prospective Cohort Study, Ahmed M. Salman, Fatma M. Sayed, Hesham Mohammed Hamad
Journal of Medicine in Scientific Research
Background In anovulatory infertility Polycystic ovary syndrome (PCOS) plays a leading role, characterized by endocrine and metabolic disturbances. While metformin is usually used to decrease insulin resistance and restore ovulation, myoinositol has emerged as a promising alternative with fewer side effects. This study aimed to evaluate and compare the effectiveness of metformin and myoinositol as adjuvant treatments in infertile women with PCOS in ovulation induction cycles. Patient and methods This prospective cohort study included 192 women diagnosed with PCOS-related infertility, divided into two groups (n = 96 each) receiving either metformin or myoinositol for 3 months prior to ovulation induction. …
Glycolic Acid (Ga) Peel Versus Dermapen In Management Of Acne Scars Among Egyptian Patients: A Comparative Study, Rania Emam Elbanna
Glycolic Acid (Ga) Peel Versus Dermapen In Management Of Acne Scars Among Egyptian Patients: A Comparative Study, Rania Emam Elbanna
Journal of Medicine in Scientific Research
Aim of the work: To assess and contrast dermapen, glycolic acid (GA) peel, and a combination of the two therapys' safety and effectiveness in treating acne scars. Cases and methods: Thirty cases with acne scars participated in this trial. Ten cases each were divided into three cohorts at random; cohort I had dermapen therapy, whereas cohort II received glycolic peel therapy. Both procedures were administered to Cohort III. Six sessions were given to each case at intervals of two weeks. The quartile grading scale, the degree of case satisfaction, and the qualitative global scar grading system before and after therapy …
Introduction To The Nitrogen Cycle, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Introduction To The Nitrogen Cycle, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Supplementary Content for Aquaponics: Farming Fish and Growing Greens for Grades 9–12
This PowerPoint slide provides readers with an introduction to the Nitrogen cycle. This book was published by the Purdue University Press. Copyright 2026.
Permission: Illinois-Indiana Sea Grant
How To Measure The Level Of Nitrogen In An Aquaponics System, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
How To Measure The Level Of Nitrogen In An Aquaponics System, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Supplementary Content for Aquaponics: Farming Fish and Growing Greens for Grades 9–12
This PowerPoint slide shows readers how to measure the level of Nitrogen in an aquaponics system. This book was published by the Purdue University Press. Copyright 2026.
Permission: Illinois-Indiana Sea Grant
Plants In An Aquaponics System, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Plants In An Aquaponics System, Amy M. Shambach, Rebecca M. Ward, J. Stuart Carlton, Kwamena K. Quagrainie, Tomas O. Höök
Supplementary Content for Aquaponics: Farming Fish and Growing Greens for Grades 9–12
This PowerPoint slide provides readers with information on plants in an aquaponics system. This book was published by the Purdue University Press. Copyright 2026.
Permission: Illinois-Indiana Sea Grant
Staff Education To Enhance Provider Knowledge On Lifestyle Modification For Hypertension Management, Chinyere Maria Assumpta Ofoegbu
Staff Education To Enhance Provider Knowledge On Lifestyle Modification For Hypertension Management, Chinyere Maria Assumpta Ofoegbu
Walden Dissertations and Doctoral Studies
Summary A doctor of nursing practice (DNP) staff education project was designed to enhance healthcare providers' knowledge of lifestyle interventions for hypertension management. At the practice site, primary healthcare providers were not regularly integrating lifestyle counseling. The practice-focused question guiding this project was: In primary care providers, how does implementing an evidence-based lifestyle education training program for hypertension management affect provider knowledge? An in-person educational session was provided to ten (10) healthcare practitioners who voluntarily participated. Pre- and post-training knowledge assessments was the analytical techniques employed to examine changes in provider comprehension of lifestyle-based hypertension care. Descriptive statistics and paired-sample …
Butte Priority Soils Operable Unit (Bpsou) 2025 Monthly Progress Report. Consent Decree For The Butte Priority Soils Operable Unit. Civil Action No. Cv 89-039-Bu-Seh, Atlantic Richfield Company
Butte Priority Soils Operable Unit (Bpsou) 2025 Monthly Progress Report. Consent Decree For The Butte Priority Soils Operable Unit. Civil Action No. Cv 89-039-Bu-Seh, Atlantic Richfield Company
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Capturing Sclera Anisotropy Using Direct Collagen Fiber Models: Linking Microstructure To Macroscopic Mechanical Properties, Fengting Ji, Xuehuan He, Frederick Sebastian, Mohammad R. Islam, Hannah Schilpp, Bingrui Wang, Yi Hua, Rouzbeh Amini, Ian A. Sigal
Capturing Sclera Anisotropy Using Direct Collagen Fiber Models: Linking Microstructure To Macroscopic Mechanical Properties, Fengting Ji, Xuehuan He, Frederick Sebastian, Mohammad R. Islam, Hannah Schilpp, Bingrui Wang, Yi Hua, Rouzbeh Amini, Ian A. Sigal
Mechanical Engineering Faculty Publications
Collagen fibers are essential to the mechanical behavior of soft tissues, including sclera. Conventional models often represent these fibers statistically, potentially missing crucial aspects of their role in tissue behavior. In this study, we expand on a direct fiber modeling approach that we recently presented based on explicitly representing the sclera long, interwoven fiber bundles. Specifically, our goal was to capture specimen-specific 3D fiber architecture and anisotropic mechanics of four ovine sclera samples (superior from Eye-1, temporal and superior from Eye-2, and temporal from Eye-3), each tested under five conditions: equi-biaxial (1:1) and four non-equi-biaxial (1:0.75, 0.75:1, 1:0.5, and 0.5:1). …
Clinical And Dosimetric Dataset Of Time-To-Event Normal Tissue Complication Probability For Osteoradionecrosis, Natalie A West, Serageldin Kamel, Andrew Wentzel, Zaphanlene Kaffey, Moamen Abdelaal, G Elisabeta Marai, Guadalupe Canahuate, Xinhua Zhang, Melissa M Chen, Kareem A Wahid, Jillian Rigert, Kristy K Brock, Mark Chambers, Adegbenga O Otun, Ruth Aponte-Wesson, Renjie He, Mohamed A Naser, Katherine A Hutcheson, Abdallah S R Mohamed, Lisanne V Van Dijk, Amy C Moreno, Stephen Y Lai, Clifton D Fuller, Laia Humbert-Vidan
Clinical And Dosimetric Dataset Of Time-To-Event Normal Tissue Complication Probability For Osteoradionecrosis, Natalie A West, Serageldin Kamel, Andrew Wentzel, Zaphanlene Kaffey, Moamen Abdelaal, G Elisabeta Marai, Guadalupe Canahuate, Xinhua Zhang, Melissa M Chen, Kareem A Wahid, Jillian Rigert, Kristy K Brock, Mark Chambers, Adegbenga O Otun, Ruth Aponte-Wesson, Renjie He, Mohamed A Naser, Katherine A Hutcheson, Abdallah S R Mohamed, Lisanne V Van Dijk, Amy C Moreno, Stephen Y Lai, Clifton D Fuller, Laia Humbert-Vidan
Faculty, Staff and Student Publications
Osteoradionecrosis of the jaw (ORNJ) is a radiation-induced late toxicity that can dramatically decrease patients' quality of life. Recent increases in survival rates of head and neck cancers associated with human papillomavirus (HPV) infection have resulted in a higher frequency of radiation-induced toxicities, particularly ORNJ. Recent work with Normal Tissue Complication Probability (NTCP) models and a Weibull Accelerated Failure Time (WAFT) model have further developed our understanding of ORNJ clinical/dosimetric risk factors and longitudinal features, respectively. In this data descriptor, 1129 head and neck cancer (HNC) patients received curative intent radiotherapy (RT) at MD Anderson Cancer Center and were followed …
An Integrated Single-Cell And Spatial Transcriptomic Atlas Of Thyroid Cancer Progression Identifies Prognostic Fibroblast Subpopulations, Matthew A Loberg, George J Xu, Sheau-Chiann Chen, Hua-Chang Chen, Claudia C Wahoski, Kailey P Caroland, Megan L Tigue, Heather A Hartmann, Jean-Nicolas Gallant, Courtney J Phifer, Andres A Ocampo, Dayle K Wang, Reilly G Fankhauser, Kirti A Karunakaran, Chia-Chin Wu, Maxime Tarabichi, Sophia M Shaddy, James L Netterville, Sarah L Rohde, Carmen C Solórzano, Lindsay A Bischoff, Naira Baregamian, Barbara A Murphy, Jennifer H Choe, Jennifer R Wang, Eric C Huang, Quanhu Sheng, Luciane T Kagohara, Elizabeth M Jaffee, Ryan H Belcher, Ken S Lau, Fei Ye, Ethan Lee, Vivian L Weiss
An Integrated Single-Cell And Spatial Transcriptomic Atlas Of Thyroid Cancer Progression Identifies Prognostic Fibroblast Subpopulations, Matthew A Loberg, George J Xu, Sheau-Chiann Chen, Hua-Chang Chen, Claudia C Wahoski, Kailey P Caroland, Megan L Tigue, Heather A Hartmann, Jean-Nicolas Gallant, Courtney J Phifer, Andres A Ocampo, Dayle K Wang, Reilly G Fankhauser, Kirti A Karunakaran, Chia-Chin Wu, Maxime Tarabichi, Sophia M Shaddy, James L Netterville, Sarah L Rohde, Carmen C Solórzano, Lindsay A Bischoff, Naira Baregamian, Barbara A Murphy, Jennifer H Choe, Jennifer R Wang, Eric C Huang, Quanhu Sheng, Luciane T Kagohara, Elizabeth M Jaffee, Ryan H Belcher, Ken S Lau, Fei Ye, Ethan Lee, Vivian L Weiss
Faculty, Staff and Student Publications
Although well-differentiated thyroid carcinoma (WDTC) is characterized by a robust treatment response, aggressive subtypes, such as anaplastic thyroid carcinoma (ATC), remain highly lethal. To understand thyroid cancer evolution in both children and adults, we analyzed single-cell transcriptomes of 423,733 cells from 81 samples and spatially resolved key tumor and microenvironment populations across 28 tumors with spatial transcriptomics, including rare and unique composite WDTC/ATC tumors and pediatric diffuse sclerosing thyroid carcinomas. Additionally, we identified gene signatures of stromal cell populations in 5 large thyroid cancer bulk RNA-sequencing cohorts. Through this multi-institutional effort, we defined a population of POSTN+ myofibroblast cancer-associated fibroblasts …
The Yeh Pilus Adhesin Is Equipped With An Α-Helical Flap Motif, Which Contributes To Pectin Adherence, Kevin O Tamadonfar, Roger D Klein, Edward D B Lopatto, Maxwell I Zimmerman, Philippe N Azimzadeh, Denise A Sanick, Justin R Porter, Jesus Bazan Villicana, Jerome S Pinkner, Bo Huey Chiang, Nathaniel C Gualberto, Karen W Dodson, Michael L Patnode, George M H Et Al., Gregory R Bowman, Scott J Hultgren
The Yeh Pilus Adhesin Is Equipped With An Α-Helical Flap Motif, Which Contributes To Pectin Adherence, Kevin O Tamadonfar, Roger D Klein, Edward D B Lopatto, Maxwell I Zimmerman, Philippe N Azimzadeh, Denise A Sanick, Justin R Porter, Jesus Bazan Villicana, Jerome S Pinkner, Bo Huey Chiang, Nathaniel C Gualberto, Karen W Dodson, Michael L Patnode, George M H Et Al., Gregory R Bowman, Scott J Hultgren
2020-Current year OA Pubs
The Yeh chaperone-usher pathway (CUP) pilus adhesin is encoded in one-half of all
Assessment Of Body Fat Percentage In Emirati Females: A Comparative Analysis Of Bia Vs. Dxa, Dalia Haroun, Aseel Ehsanallah
Assessment Of Body Fat Percentage In Emirati Females: A Comparative Analysis Of Bia Vs. Dxa, Dalia Haroun, Aseel Ehsanallah
All Works
Introduction: Obesity is a significant health issue in the UAE. Accurate body composition assessment is crucial for managing obesity-related health risks. This study aimed to evaluate the agreement between bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA) in measuring body composition among Emirati females. Methods: This cross-sectional study involved 95 healthy Emirati females aged 17–27 years. Paired samples t-tests, correlation analyses, and Bland-Altman plots were used to compare the two methods (BIA vs. DXA). Results: BIA significantly underestimated % fat and fat mass (FM) while overestimating fat-free mass (FFM) compared to DXA. The mean difference in % fat was …
Exploring The Leadership Journeys Of Female College Presidents At Health Professions Focused Institutions: An Explanatory Sequential Mixed Methods Study, Caroline S. Zeind, Bobbie Ann Adair White, Yoon Soo Park, Tewodros Eguale, Anne Thompson
Exploring The Leadership Journeys Of Female College Presidents At Health Professions Focused Institutions: An Explanatory Sequential Mixed Methods Study, Caroline S. Zeind, Bobbie Ann Adair White, Yoon Soo Park, Tewodros Eguale, Anne Thompson
Journal of Research on the College President
National data on the academic presidency reflect a long-standing gender gap with little known about the presidency at health professions focused institutions (HPFIs). This mixed methods study explored the relationships between the academic presidency and institutional characteristics of HPFIs, and the leadership journeys of female presidents at HPFIs. An analysis of institutional and leadership data for 487 HPFIs was conducted using a quantitative approach, followed by interviews of 15 female presidents at HPFIs to understand their perceptions of the barriers, and factors that helped with presidency attainment. The results of 479 HPFIs revealed that only 36.3% of women served as …
Lung Epithelial And Alveolar Macrophage-Like Cell Interactions Significantly Modify Innate Responses To Bacterial Endotoxin With The Involvement Of Direct Cellular Contacts, Tnf-Α, Icam1 And Mcp-1, Connor Wood, Shagun Khera, Minjeong Woo, Vikram Sharma, Justyna Lopatecka, Frederic Coulon, Zaheer Nasir, Vincent Delorme, Simon K. Jackson, György Fejer
Lung Epithelial And Alveolar Macrophage-Like Cell Interactions Significantly Modify Innate Responses To Bacterial Endotoxin With The Involvement Of Direct Cellular Contacts, Tnf-Α, Icam1 And Mcp-1, Connor Wood, Shagun Khera, Minjeong Woo, Vikram Sharma, Justyna Lopatecka, Frederic Coulon, Zaheer Nasir, Vincent Delorme, Simon K. Jackson, György Fejer
School of Biomedical Sciences
Introduction: Lung alveolar macrophages (AMs) and epithelial cells form the first line of defense against inhaled pathogens. Their interactions strongly influence innate immune responses in the lung, yet the mechanisms underlying this cross-talk remain incompletely understood. Methods: In this study, we established a co-culture system using a primary model of AMs (MPI alveolar macrophage-like cells) and MLE-12 alveolar epithelial cells to investigate innate responses and cellular interactions during bacterial lipopolysaccharide (LPS)-induced TLR4 activation. Results: Cytokine and chemokine profiling revealed that co-cultures exhibited significantly enhanced proinflammatory responses to both LPS and TLR2 ligands—including IL-6, TNF-a, and MCP-1 secretion—compared with mono-cultures. Strikingly, …