Digital Commons Network^™

Emg Analysis Of The Upper Body During Different Cycling Positions, Nicholas G. Cariquitan, Amara Dumas, Christiane R. O'Hara

International Journal of Exercise Science: Conference Proceedings

Elite, novice, and beginner cyclists all encounter varying positions on the bicycle to meet comfort and/or performance needs. These positions must take into account the complex relationship between muscular activation, flexibility, and the limits of human biomechanics. PURPOSE: To investigate three bicycle positions and the effect of the rider’s upper body muscular activation and comfort. The bicycle position was defined by hip angles: normal (120-130 degrees), aggressive (110-115 degrees), and upright posture (140-150 degrees), while maintaining a constant knee angle (28-32 degrees). METHODS: 10 college-aged participants with cycling experience from Cal Poly San Luis Obispo and the surrounding area were …

Effects Of Acute Sleep Reduction And Aerobic Exercise On Metabolic Function In Healthy Adults, Eric Lessard, Gracie Dupuis, Jocelyn Kaveney, Braden Wilson, Grahm Mcginnis, Ryan Perkins

International Journal of Exercise Science: Conference Proceedings

INTRODUCTION: The number of adults who receive insufficient sleep is progressively increasing, impacting the established relationship between sleep and metabolic function. PURPOSE: The purpose of this study was to explore the effects of acute sleep reduction on metabolic variables at rest and during aerobic exercise. METHODS: Healthy, active adults (n=11; 26.4±5.4 yr; 45% female) were screened to ensure eligibility (i.e., meeting the CDC’s sleep recommendations of 7-9hr/night, apparently healthy, recreationally active, and non-smoking), characterize body composition via DXA and measure maximal cardiovascular capacity (VO2max). Utilizing a within subjects, repeated measures design, participants completed an initial 7d period of …

Correlational Analysis Between Fat-Free Mass And Physical Performance In College Students, Rhea Misra, Giselle Murillo, Fraz Tahir, Tianou Zhang

International Journal of Exercise Science: Conference Proceedings

Fat-free mass (FFM), the body’s metabolically active tissue excluding fat, plays a critical role in strength, endurance, and overall physical performance. PURPOSE: The objective of this study is to investigate the association between FFM and physical performance in college students. METHODS: FFM was evaluated using the BodPod in a sample of 21 male and 12 female students. Various performance metrics were measured, including handgrip strength, aerobic capacity (via VO₂max test), anaerobic capacity (peak power and peak force through Wingate test), vertical jump height, and broad jump distance. Spearman correlations were used to evaluate correlations between FFM and performance …

Interleukin-6 As A Mediator Of Circadian And Sex Differences In Exercise-Induced Stat3 And Autophagy Signaling, Srushti Wagh, Ariana Khzarjyan, Joshua Corpuz, Elias M. Malek, Charli Aguilar, Michael Dial, Paula Martinez, Graham Mcginnis

International Journal of Exercise Science: Conference Proceedings

Circadian rhythms are highly conserved across tissues and play an important role in regulating how the heart responds to physiological and pathological stress. Exercise is known to be cardioprotective, yet the impact of exercise timing on molecular signaling is still being explored. Interleukin-6 (IL-6) is an exercise-induced cytokine which has been shown to be important to cardioprotection and metabolism. It is currently unknown how exercise timing modulates the IL-6 signaling pathway in the heart.

PURPOSE: To investigate how time-of-day and IL-6 influence exercise-induced activation of STAT3 and its downstream signaling pathways in male and female mouse hearts.

METHODS: Wild-type and …

Comparison Of Lower Limb Sagittal Plane Kinematics Measured Using Opencap And Traditional Mocap During Single Limb Squat Analysis In Patients Post-Aclr, Alexander Chen, Jiaqi Wang, Susan Sigward, Willa Ma, Grace Choi

International Journal of Exercise Science: Conference Proceedings

OpenCap (Stanford University) uses standard smartphone cameras and computer vision algorithms to estimate joint kinematics without markers. With affordable equipment and reasonable setup procedures, it may provide an alternative to visual assessment of movement impairments in the clinic. Subtle alterations in joint kinematics can be relevant to the interpretation of recovery progress following musculoskeletal injury or surgery such as anterior cruciate ligament reconstruction (ACLr). It is important to understand the level of agreement between new tools for assessment and gold standard kinematic measures. PURPOSE: To determine concurrent validity of kinematic data collected using OpenCap and gold standard technologies during …

The Effect Of Fatigue On Hip, Knee, And Ankle Kinetics During Rear Foot-Elevated Split Squats, Sara C. Mills, Jaime Alvarado, Tyler Lindholm, Michele Leblanc Facsm

International Journal of Exercise Science: Conference Proceedings

Rear foot-elevated split squats (RFESS) are a widely used movement to increase lower body strength, but little is known about how fatigue alters joint torque demands across the ankle, knee, and hip. Previous research has shown that fatigue changes kinematics during RFESS, increasing hip and knee motion while reducing ankle movement, but the effect on joint torques remains unclear. PURPOSE: To examine the effects of fatigue on ankle, knee, and hip torque in the sagittal and frontal planes during the eccentric and concentric phases of the RFESS in active females aged 18–25. METHODS: Participants performed repeated body weight RFESS until …

High-Dose Sodium Supplementation On Hydration And Thermoregulatory Responses While Cycling In The Heat, Melani Kelly

International Journal of Exercise Science: Conference Proceedings

Sodium is commonly included in sports beverages to promote hydration and support carbohydrate (CHO) absorption, typically at concentrations of ~270-400mg. Recently, high-dose sodium supplements, often approaching 1000mg and lacking CHO, have entered the market with minimal evidence to support their use. PURPOSE: Investigate how hydration and thermoregulatory responses change during cycling in the heat when consuming a supplement containing 810mg of sodium. METHODS: Twenty recreationally active participants (15 males, 5 females; age = 23.4 ± 2.8) completed a 2-h bout of cycling in an environmental chamber (37.3℃, 59.1 ± 4.4% relative humidity) on two occasions separated by > 7 …

Understanding The Effects Of Training On Brain And Muscle Hemodynamics During Exercise-Induced Muscle Fatigue, Aqueen Lenon, Christine Dy, Stefan Keslacy

International Journal of Exercise Science: Conference Proceedings

BACKGROUND: While the muscle fatigue during weightlifting exercise is well-documented, the relationship of brain/muscle activity are less known. PURPOSE: to investigate the changes in oxygenation levels in the brain and muscles during resistance training, comparing these effects between athletes (ATH) and sedentary (SED) individuals. METHODS: 24 participants (14 SED, 10 ATH) were recruited. The bench press protocol included four sets of twelve repetitions at a weight corresponding to a Rate of Perceived Exertion (RPE) of 6. Oxygenation levels in prefrontal cortex and the right triceps muscle were continuously monitored using near-infrared spectroscopy (NIRS) (Oxymon Mk III). NIRS data …

Intensity Over Effort: Exercise Prescription Strategies For Glycemic Control, Oscar Chavez Jr., Marissa Ramirez, Jacob Dawes, Isaac Chapman, Kosar Valaei, Maja Gebauer, Christine Mermier, Jonathan Little Facsm, Luotao Lin, Gretchen Ray, Roberto M. Alvidrez, Zachary Mang, Fabiano T. Amorim, Valmor Tricoli, Flavio De Castro Magalhaes

International Journal of Exercise Science: Conference Proceedings

ABSTRACT

Resistance exercise (RE) is effective in mitigating the development of type 2 diabetes (T2D) and prediabetes, but long-term adherence is low in these populations. Continuous glucose monitoring (CGM) devices are important tools in clinical practices to assist glycemic control. Previous meta-analysis shows the functionality of CGM devices among different exercise modalities but mentions the lack of studies with controlled diet and physical activity levels in free-living conditions. PURPOSE: To examine whether perceived effort during RE influences glycemic control and psychological outcomes in individuals with prediabetes and T2D using CGM under free-living conditions. METHODS: In randomized order, 25 …

Dexterity Assessment Scores Vary With Controller Type But Not Super Smash Bros. Ultimate Player Skill, Jacob D. Cervantes, Dillon Harris, Zachary R. Mcfadden, Steven B. Machek

International Journal of Exercise Science: Conference Proceedings

Within the expanding Esports industry, competitive Super Smash Bros Ultimate (SSBU) players require high neuromotor execution. They consequently select controllers and permit functional modifications to match the individual precision and dexterity preferences within their playstyle. PURPOSE: To examine how skill level and controller preference impact dexterity scores in SSBU players of differing skill relative to each other and non-gamers. METHODS: 56 (22 male casual CAS; 24y ± 4; play >4 hr per week, 15 male ES; 24y ± 4; top 150 globally- ranked competitive SSBU players, and 19 non-gamer controls NG; 24y ± 5; 16F/3M) subjects voluntarily participated …

Different Glycemic Control Responses In Women And Men With Type 2 Diabetes And Prediabetes To Resistance Exercise, Kosar Valaei, Oscar Chavez Jr., Marissa Ramirez, Jacob D. Dawes, Isaac Chapman, Maja Gebauer, Christine M. Mermier, Jonathan Little, Luotao Lin, Gretchen M. Ray, Roberto Mota, Zachary A. Mang, Fabiano Amorim, Valmor Tricoli, Flavio De Castro Magalhaes

International Journal of Exercise Science: Conference Proceedings

Resistance exercise (RE) is recommended for individuals with type 2 diabetes (T2D) and prediabetes to improve glycemic control, but sex differences remain unclear. PURPOSE: To investigate sex-related differences in glycemic responses to RE in individuals with T2D and prediabetes METHODS: Twenty-five participants (12 males, 13 females, 36–78 year) with T2D or prediabetes completed four randomized crossover sessions: a high-intensity (HI) RE session (3 sets × 8 reps, 75%-1RM, 120 seconds interval), a rest-redistribution (RR) RE session (6 sets × 4 reps, 75%-1RM, 60 seconds interval), a low-load (LL) RE session (3 sets × 16 reps, 37.5%-1RM, 103 seconds …

Unlocking The Potential Of Citrulline Malate: A Pilot Study, Fabiola E. Bejarano, Elisa L. Milkie, Parker Andersen, Jenevieve L. Roper Facsm

International Journal of Exercise Science: Conference Proceedings

Citrulline malate (CM) is an ergogenic aid hypothesized to improve exercise performance by promoting nitric oxide (NO) production resulting in increased vasodilation, blood flow, and oxygen and nutrient delivery to working muscles. It is also thought to increase the synthesis of ATP and aerobic efficiency via malate and the TCA cycle. Prior research demonstrates improvements in upper and lower body submaximal resistance training exercise performance in females; however, limited research exists on the effects of CM supplementation on submaximal aerobic exercise performance in females. PURPOSE: Determine the effects of acute CM supplementation on submaximal time-trial (TT) performance in females. …

Use Of A Smartphone App Influences Diet Quality Among College Students., Alexis Arle, Mandy Korpusik, Delaram Yazdansepas, Gabrielle Besio, Samantha Chuakay Lim, Cameron Sumaquial, Hawley C. Almstedt

International Journal of Exercise Science: Conference Proceedings

Diet quality can protect or increase risk for noncommunicable diseases (NCDs). Diets rich in carotenoids are linked to reduced risk of NCDs. Dietary carotenoids can be measured in the skin and can serve as a biomarker of fruit and vegetable intake. PURPOSE: The purpose of this study was to investigate whether use of the In2Eat app improved diet quality among college students. METHODS: We administered a baseline survey including the Diet Quality Questionnaire (DQQ). Participants were also tested for skin carotenoid levels using a spectrophotometer (Konica Minolta 600D) as an indicator of diet quality. Participants were asked to use the …

Trunk Rotational Range Of Motion And Abdominal Oblique Strength In High School And Collegiate Baseball Pitchers: Implications For Performance And Energy Flow, Belinda Aldern, Arnel Aguinaldo, Avery Takata, Antonio Squillante

International Journal of Exercise Science: Conference Proceedings

BACKGROUND: Baseball pitching requires complex sequencing of the kinetic chain, with the trunk serving as an integral role for linking the lower body to the upper body. Despite past research on energy flow in pitching, there is an increased need to study age-specific performance. PURPOSE: The purpose of this study was to examine differences in Trunk Rotational Range of Motion (TRROM) and Abdominal Oblique Strength (AOS) between high school and collegiate baseball pitchers and how these variables relate to performance and mechanical energy flow through the lumbosacral (L5S1) joint. METHODS: 12 High School and 12 Collegiate aged pitchers …

A Case Of Listeria Monocytogenes Bacteremia In A Middle-Aged Woman With A History Of Primary Biliary Cholangitis, Caleb Smack, Jared T. Lausen, Aaron Mills

Eastern Virginia Medical Journal

In this report, we discuss the case of a patient with Listeria monocytogenes bacteremia likely resulting from primary biliary cholangitis (PBC) induced cirrhosis. We aim to bolster the body of literature on Listeria bacteremia and establish PBC as a risk factor for this rare complication. Our patient, who presented with sepsis, was subsequently found to have Listeria bacteremia and received intravenous antibiotic treatment of ampicillin for 3 total weeks with complete resolution of her disease. This is the first case suggesting that cirrhosis as a result of PBC may be an independent risk factor for Listeria bacteremia. In patients at …

“No Ifs, Ands, Or Butts”: Analyzing Race And Gender In Sex And The City Through Black Feminist Theory, Daniella Orias

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This article analyzes Season 3, Episode 5 of Sex and the City, “No Ifs, Ands, or Butts,” through the lens of Black feminist theory. It investigates how race and gender are constructed, stereotyped, and selectively represented within the episode’s narrative. The analysis focuses on two Black characters who were featured only in one episode of the series, Adeena and Chivon, and examines how the show portrays harmful stereotypes such as the angry Black woman (Adeena) and sexualized Black male (Chivon) in the episode. These limited and harmful representations are further scrutinized by the fact that the show is often …

Non-Invasive Monitoring Of Camel Hair From A Free-Grazing Herd As A Biomarker In Linking Environmental Exposure And Nutritional Status In Desert Ecosystems, Ibrahim Albokhadaim

The Thai Journal of Veterinary Medicine

Camels are vital livestock in arid regions, yet their elemental exposure remains underexplored, particularly through non-invasive biomarkers. This study is novel in applying camel hair as a non-invasive, long-term biomarker to assess nutritional adequacy and environmental exposure in a free-grazing desert herd, with age-stratified evaluation of essential and toxic element accumulation. For this purpose, a cross-sectional study was conducted on a herd of 18 apparently healthy camels (≤6 months: 28%; >6 months: 72%). Initially, hair samples were collected, washed, digested, and analyzed using inductively coupled plasma mass spectrometry (ICP-MS). The samples were then analyzed to determine the concentrations of 12 …

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.

Enhancing Wound Healing With Synergistic Dual-Drug Electrospun Roflumilast And L-Arginine Loaded Pla/Pva Nanofibers Through Fabrication, Optimization, And In Vivo Assessment, Samar A. Salim

Nanotechnology Research Centre

Current trends in improved wound management emphasize the development of dual-drug-loaded electrospun nanofibrous scaffolds. Herein, electrospun dual-drug loaded PLA/PVA nanofibrous scaffolds, incorporating roflumilast, a selective phosphodiesterase-4 inhibitor with anti-inflammatory activity, and L-arginine, a precursor to nitric oxide with stimulating activity towards wound healing and tissue regeneration, were developed. A dual-spinneret electrospinning process enabled the coloading of drugs in PLA and PVA phases. Scaffolds were characterized by SEM, FTIR, and XRD, showing consistent fiber morphology, and amorphous drug formation. FTIR analysis was performed to confirm drug–polymer compatibility and successful incorporation of roflumilast and L-arginine within the PLA/ PVA nanofibrous matrix. Swelling …

P-78. Susceptibility Of Omadacycline In Bone And Joint Infections: Pathogen Susceptibility And Regimen Decisions From An Ongoing Randomized Controlled Trial, Amy Y. Kang, Evelyn A. Flores, Donna Phan Tran, Buchen (Olivia) Han, Isabel Payan, Guarina Garcia Delgado, Loren G. Miller

Pharmacy Faculty Articles and Research

Background   Treatment of Bone and joint infections (BJIs) with oral antibiotics may have benefits compared to IV therapy. Yet oral treatment options may be limited by lack of options due to antibiotic-resistant pathogens and tolerability concerns. Omadacycline has in vitro activity against common BJI pathogens, including MRSA and most Enterobacterales. However, real-world susceptibility data and implications for oral therapy are limited.   Methods

We conducted a descriptive analysis of data from adult patients enrolled to date in an open-label, randomized controlled trial of comparing omadacycline-containing antibiotic regimen vs. standard of care (SOC) antibiotics for BJIs. Omadaycline susceptibility was assessed on available …

686. Antibiotic Prescribing For Urinary Tract Infections In Outpatient Settings: A Multicenter Assessment Based On The Five Ds Of Stewardship, Amy Y. Kang, Oliver Tan, Sunwoo Oh, Nikki Derleth, Megan Shieh, Helen Vu, Inna Tagarino, Audrey Harrington, Deborah Kupferwasser, Loren G. Miller

Pharmacy Faculty Articles and Research

Background   Urinary tract infections (UTIs) are a leading cause of outpatient antibiotic use. Prior studies have documented inappropriate prescribing during outpatient UTI visits, but few have assessed intervention opportunities using a structured stewardship framework. We evaluated UTI prescribing practices in a healthcare system using the Five Ds framework: Diagnosis, Drug, Dose, Duration, and De-escalation.   Methods

We conducted a retrospective study across 4 medical centers and > 20 outpatient clinics within the Los Angeles County Department of Health Services, the second largest U.S. safety net healthcare system. To ensure adequate representation across sites while maintaining feasibility for manual chart review, we reviewed …

Ethics Of Artificial Intelligence For Lawyers: Shall We Play A Game? The Rise Of Artificial Intelligence And The First Cases, Cliff Mckinney

Arkansas Law Notes

In the 1983 movie WarGames, a young computer hacker accidentally accesses a United States military supercomputer programmed to run nuclear war simulations. Four decades after WarGames, lawyers are now facing similar challenges of learning to use and communicate with artificial intelligence––hopefully without destroying the world. Artificial intelligence tools, such as ChatGPT, Claude, and Gemini, are quickly being incorporated into legal practice. These systems can draft documents, perform analysis, and support other legal tasks. While lawyers adjust to these new technologies, courts and regulatory authorities are actively developing appropriate frameworks to guide and supervise the use of these tools within the …

Conducting A Qualitative Umbrella Review For Novice Researchers: A Critical Reflection Of Primary Documents, Mónica Fontana, Celia Camilli Trujillo

The Qualitative Report

The need for scientific evidence in education has accelerated systematic reviews. However, the practice of conducting umbrella reviews is not yet common in education. Among the possible reasons for the scarce number of umbrella reviews in education is the lack of knowledge of the steps required to conduct them and the specific challenges of this method. Their usefulness in the educational context lies in their ability to offer new findings of great scope and transferability based on evidence from multiple systematic reviews in an efficient and in-depth manner. This study provides a critical reflection on the methodological implications of conducting …

Blood Product Transfusion And Coagulopathy In Children With Traumatic Brain Injury: A Narrative Review., Robert Marcel T. Huibonhoa, Niranjan Vijayakumar, Daniel Kelly, Oliver Karam, Madhuradhar Chegondi

Manuscripts, Articles, Book Chapters and Other Papers

Traumatic brain injury (TBI) is a leading cause of critical illness and mortality in children. Transfusion of blood products, a common intervention in the management of pediatric TBI, has important implications for related principles, including trauma-induced coagulopathy, cerebral perfusion, and cerebral oxygen delivery. Knowledge gaps persist due to the limited availability of pediatric-specific data regarding blood product transfusion in TBI. In particular, there is a lack of prospective studies defining appropriate specific laboratory thresholds and transfusion targets, as well as insufficient evidence to guide the weighing of potential benefits against transfusion-related risks in this population. Although blood product transfusion in …

Policy, Misinformation, And Mortality: The Effects Of Abortion Restrictions On Maternal Outcomes, Gabrielle Samiratedu Dmsc, Mcms, Pa-C

Lynchburg Journal of Medical Science

The objective of this review is to evaluate the effects of restrictive abortion laws on maternal mortality and morbidity in the United States. Even before the landmark reversal of Roe v. Wade, the US had one of the highest maternal mortality rates among other high-income countries, and rates are expected to continue to rise in states with restrictive abortion policies. Electronic databases and public health data were analyzed to assess clinical outcomes, access to care, and disparities associated with abortion restrictions nationally and internationally. The findings suggest that states with highly restrictive abortion policies experience higher rates of maternal morbidity …

Circulating Tumor Dna: Reducing Burden In Hpv+ Oropharyngeal Cancer Surveillance, Liza M. Joseph Pa-C

Lynchburg Journal of Medical Science

This review examines the rising prevalence of human papillomavirus-related (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) and evaluates the role of circulating tumor HPV DNA (ctHPVDNA) in diagnosis and post-treatment surveillance. A comprehensive literature search of electronic databases, including PubMed, Medline, Cochrane Library, and Google Scholar, identified studies that validated ctHPVDNA as a biomarker with high sensitivity and specificity, assessed its cost-effectiveness, and explored patient and provider perceptions. Clinical evidence supports that plasma-based ctHPVDNA is the most accurate method for detecting disease recurrence and quantifying tumor burden. Patient perception studies reported high confidence in ctHPVDNA testing, while providers viewed it as …

Transcarotid Artery Revascularization Current Role And Outcomes, Heather Warren

Lynchburg Journal of Medical Science

This paper aims to evaluate the role of transcarotid artery revascularization (TCAR) in the management of carotid artery stenosis. A comprehensive literature search was conducted using PubMed to identify the role and current outcomes of TCAR compared to carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TF-CAS). Carotid artery stenosis accounts for a significant portion of ischemic strokes. The global burden of stroke includes permanent disability and death. Medical and surgical interventions following ischemic stroke are aimed at reducing the future incidence of ischemic stroke based on the underlying etiology. Symptomatic carotid artery stenosis management includes optimal medical management and …

Wilderness Therapy As An Intervention For Teens Who Are At The End Of Their Rope, Blake C. Neal, Heather Summers

Lynchburg Journal of Medical Science

Abstract

Wilderness therapy, treatment offered in a natural setting, is offered as an alternative to traditional treatment methods (Lodato, N., Blivas, R., & Blivas, N. L. and R., 2024). This model is often used as a last resort for teens who are unsuccessful in other environments. However, when used as a blanket treatment model for all mental health concerns, there is a risk for greater harm inflicted on participants. A case study approach provides evidence of a teen in one of these settings struggling with an eating disorder and self-harm. Although potentially helpful with some concerns, we learn from this …

Grover's Disease: A Review Of The Current Treatment Options, Dustin Ross, Dmsc, Mph, Pa-C

Lynchburg Journal of Medical Science

Grover’s disease, also known as transient acantholytic dermatosis, is an uncommon dermatologic condition characterized by pruritic papulovesicular eruptions that predominantly affect the trunk of older adults. Although the disease is often self-limited, it may significantly impair quality of life. This review summarizes treatment options and emerging therapies for Grover’s disease reported in the literature since 2019. A comprehensive search of PubMed and MEDLINE identified 1,068 records, of which thirteen publications met inclusion criteria, including one systematic review, one narrative review, one nonrandomized controlled study, nine case reports, and one fact sheet, representing a total of 337 patients. The literature demonstrates …

Weight-Loss Efficacy Of Glp-1 Receptor Agonists Relative To Lifestyle-Based Interventions, Amy Betterton

Lynchburg Journal of Medical Science

ABSTRACT

This clinical review compares the effectiveness of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) with traditional lifestyle modifications in managing obesity. This article also examines barriers to accessing the medications in both civilian and veteran populations. This clinical review was conducted through a wide-ranging review of the published literature, including clinical trials, observational studies, and review articles on lifestyle modifications, GLP-1 receptor agonists, and barriers to obesity treatment. While lifestyle modifications are generally considered a first-line approach and are cost-effective, they tend to yield only modest weight loss. In contrast, GLP-1 RAs offer significantly greater reductions in body weight as …