Digital Commons Network^™

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.

An Inflammatory And Quiescent Hsc Subpopulation Expands With Age In Humans., Ksenia R Safina, Basit Salik, Dylan Kotliar, Michelle Curtis, Jonathan D Good, Chen Weng, Shawn David, Soumya Raychaudhuri, Antonia Kreso, Jennifer J. Trowbridge, Vijay G Sankaran, Peter Van Galen

Faculty Research 2026

Aging of the blood system impacts systemic health and can be traced to hematopoietic stem cells (HSCs). Despite multiple reports on human HSC aging, a unified map detailing their molecular age-related changes is lacking. We developed a consensus map of gene expression in HSCs by integrating seven single-cell datasets. This map reveals previously unappreciated heterogeneity within the HSC population. It also links inflammatory pathway activation (TNF/NFκB, AP-1) and quiescence within a single gene expression program. This program dominates an inflammatory HSC subpopulation that increases with age, highlighting a potential target for further experimental studies and anti-aging interventions.

Polystyrene Nanoplastics As Pfas Carriers And Their Interactions With Zwitterionic Phospholipid Membranes, Jiahuiyu Fang, Tongxuan Qiao, Pranab Sarker, Xiaoxue Qin, Size Zheng, Mark J. Uline, Tao Wei

Faculty Publications

The co-occurrence of per- and polyfluoroalkyl substances (PFAS) and nanoplastics (NPs) poses a synergistic threat to environmental and human health, yet the molecular mechanisms governing PFAS–NP complexation and membrane interactions remain unclear. Using atomistic molecular dynamics simulations, we investigated the adsorption of neutral polytetrafluoroethylene (PTFE) and anionic perfluorinated compounds (perfluorooctanoic acid, PFOA, and perfluorooctanesulfonic acid, PFOS) on polystyrene NPs (3.1 and 6.7 nm) and their interactions with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes. Polystyrene NPs act as carriers, transporting PFAS molecules to the lipid/water interface, where PFAS attachment modifies NP interfacial behavior. PFAS adsorption on the NP surface is driven by …

January 16, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Ud In The News Jan. 10-16, University Of Dayton

News Releases

Inside Higher Ed featured UD's Flyer Nest, which provides students with experience in launching, financing and investing in ventures. Faculty also contributed expertise to The Conversation, NPR, The National Desk and Catholic World Report.

Leadless Versus Transvenous Dual-Chamber Pacemakers: Real-World Evidence From Aveir Dr Coverage With Evidence Development Study., Monica Lo, Anish K Amin, Marcin Kowalski, Anne Kroman, Dilip Mathew, Valay Parikh, Stanislav Weiner, Jennifer M Joseph, Leonard Ganz, Mohammed Mortada

Heart and Vascular Articles

BACKGROUND: AVEIR DR, an industry-first dual-chamber leadless pacemaker (LP), provides continuous atrioventricular synchrony through implant-to-implant (i2i) communication between atrial and ventricular LP devices. It is important to evaluate the early real-world comparative safety of AVEIR DR LP.

OBJECTIVE: To compare complications and mortality between AVEIR DR LP and dual-chamber transvenous pacemakers (TP).

METHODS: De novo LP and TP patients were identified in Medicare Fee-for-Service claims (October 2023 and December 2024). Outcomes were 30-day and 6-month complications, reinterventions, heart failure hospitalizations, and all-cause mortality. Comparisons were adjusted for demographics, comorbidities, and hospital encounter characteristics.

RESULTS: Compared to TP (N = 77 …

Noninvasive Condition Monitoring For Eccentricity Fault Detection In Large Hydro Generators, Atena Tazikeh Lemeski, Di̇dem Tekgün, Ozan Keysan, Kemal Leblebi̇ci̇oğlu, Murat Göl

Turkish Journal of Electrical Engineering and Computer Sciences

Eccentricity faults in electric machines remain a critical concern, as they generate uneven magnetic forces that increase vibration and noise, ultimately raising the risk of premature motor failure. This study proposes a method for the early detection of dynamic eccentricity (DE) faults in hydropower plants through an advanced optimization-based parameter identification technique integrated with finite element analysis (FEA). Finite element modeling (FEM) is first used to analyze an existing salient-pole synchronous generator (SPSG) from a hydroelectric power plant in Türkiye. The effects of DE faults on the SPSG’s magnetic equivalent circuit parameters are then examined under various fault severities. A …

A Deep Learning Model For Accurate Tomato Leaf Disease Identification, Maheen Shahzad, Muhammad Abdullah Javed, Erum Ashraf, Hafiz Ishfaq Ahmad, Sabeen Masood

Turkish Journal of Electrical Engineering and Computer Sciences

Recent advances in machine learning and deep learning have greatly improved how we detect plant diseases, making diagnoses more accurate, faster, and easier to scale. However, many existing solutions depend on large, pretrained models that need powerful hardware, which limits their use in the field, especially in areas with limited resources. To tackle this, we designed a custom lightweight convolutional neural network (CNN) built from scratch using 20,000 carefully selected images from the PlantVillage tomato dataset. Our model uses Squeeze-and-Excitation (SE) blocks and Swish activation functions to boost performance, reaching an accuracy of 97.7% while using far fewer computing resources …

A Novel Approach To Maximum Weighted Traffic Flow Method For Effective Signal Control, Zülal Hi̇lal Yildiz Budak, Seyi̇t Alperen Çeltek, Aki̇f Durdu

Turkish Journal of Electrical Engineering and Computer Sciences

Traffic signal management is a critical challenge due to its environmental, economic, and public health impacts. The maximum weighted flow method (MaxWeightedFlow) was developed to optimize traffic flow at isolated and coordinated urban intersections. This study proposes a new method, the novel MaxWeightedFlow, which includes two key strategies to enhance the classical approach. The first strategy reduces computational burden by estimating vehicle approach times based on instantaneous speeds, improving real-time performance. The second employs regression analysis to optimize the alpha parameter, representing the vehicle waiting coefficient. The proposed approach, the novel MaxWeightedFlow, was evaluated using real-world traffic data from Kilis, …

The Itrail Making Test (Itmt): An Evaluation Of Novel Testing Paradigms, Hidden Indices Of Measurement, And Diagnostic Accuracy In Parkinson’S Disease, Donnchadh Murphy, Jonathan Scott, Craig Newman, Rupert Noad

Peninsula Medical School

Introduction: The Trail Making Test (TMT) is an important test when assessing for cognitive difficulties in people with Parkinson’s Disease (PD). However, the pencil-and-paper format can be susceptible to administration and scoring errors and may disproportionately reflect motor impairments rather than cognitive performance. The current study sought to evaluate the reliability and diagnostic accuracy of two novel computerized versions of the TMT: iTMT-Tap and iTMT-Drag. Method: This study used a quasi-experimental diagnostic accuracy design, and included 34 healthy controls, 28 people with Parkinson’s disease with normal cognition (PD-NC), and 31 people with Parkinson’s disease mild cognitive impairment (PD-MCI). Participants were …

Volume Cxlv, Number 9, January 16, 2026, Lawrence University

The Lawrentian

No abstract provided.

Ai Derivation And Exploration Of Antibiotic Class Spaces, Adam Bess, Sean Rowland, Chris Alvin, Supratik Mukhopadhyay

Open Access Fund Publications

Purpose The rapid evolution of antibiotic-resistant bacteria poses an urgent global health crisis. A key gap in current antibiotic discovery approaches is the absence of automated chemical synthesis methods designed to systematically generate and evaluate compounds within specific antibiotic classes. We address this gap through fragment-based computational experiments that systematically explore antibiotic chemical spaces.

Methods Our computational methodology consists of three steps: fragmentation of known compounds (eMolFrag), generating new molecular structures by recombining fragments (eSynth), and filtering of candidates based on desired properties (eFilter). eFilter combines structural analysis, pathway information, and protein targets …

Student Disruptions And Teacher Turnover, Kyuhan Choi, Ying Shi, Maria Zhu

Center for Policy Research

This paper examines how exposure to disruptive students affects teacher retention using linked teacher–student administrative records from North Carolina. To address non-random classroom assignment, we instrument for classroom exposure using the school-by-grade share of disruptive students based on prior-year disciplinary infractions. A 10 percentage point increase in the share of disruptive students raises the probability of an early-career teacher leaving the school in the following year by 1.0 percentage points. Notably, working in a school environment with supportive leadership and greater teacher autonomy, particularly around student conduct policies, mitigates the impact of student disruptions.

Extra-Axial Cerebrospinal Fluid Volumes From 6 To 24 Months Of Age Are Associated With Poorer Executive Function At School-Age In Children With And Without Autism, Yichi Zhang, Robert C Mckinstry, Natasha Marrus, John R Pruett Jr., Et Al.

2020-Current year OA Pubs

BACKGROUND: Abnormally increased extra-axial cerebrospinal fluid (EA-CSF) volume is present as early as 6 months in infants later diagnosed with autism and is associated with symptom severity at the age of diagnosis, but it is unknown whether early EA-CSF enlargement has long-term impacts on other clinical domains. Executive function (EF) deficits are frequently observed in children with autism and are linked with worse academic outcomes, higher anxiety, and lower adaptive functioning. The current study examines the association between EA-CSF volume at infancy and EF at school age in a longitudinally phenotyped cohort of children with either high (HL) or low …

Cover, Cleveland State Journal Of Law And Health

Journal of Law and Health

No abstract provided.

Masthead, Cleveland State Journal Of Law And Health

Journal of Law and Health

No abstract provided.

Fda's New Approval Plan For Covid-19 Vaccines: An Inquiry Of "Benefit" Rather Than The Statutory Scope Of "Safety, Purity, And Potency"?, Henry Yat-Shing Kwan

Journal of Law and Health

This article analyzes the FDA's proposed policy plan issued in May 2025 regarding the approval of Covid-19 boosters for different groups of persons. It offers two constructive recommendations that will help prevent constitutionality challenge on impermissible intrusion of the freedom of health.

The first is to avoid using the confusing term "benefit" but instead focus on the statutory parameters of "safety, purity, and potency." The affected group can make a strong case that their free choice of vaccination should not be deprived, as long as the vaccine qualifies for the statutory thresholds of being safe, pure, and potent. They are …

Patent Pending: How The Current Patent Utility Requirement Hinders Biotechnological Innovation, Madison Drlik

Journal of Law and Health

The legal system is always playing catch up to adapt to new legal landscapes, doctrines, and technology; however, patent law needs help to compete with biotechnological research in the race towards innovation. Biotechnological research in the realm of human health and medicine often involves the use of therapeutic drugs. The field of healthcare biotechnology takes biological systems and processes and generates novel, creative solutions to a number of human health conditions. However, the translation process for a new drug, therapy, or process is long and expensive which requires investors to help the researchers and scientists move their creations from inception …

Probability Cueing In Large-Scale Environmental Search: The Role Of Landmark Cues In Statistical Learning, Shaun Dordoy, Rory Baxter, Alastair Smith

School of Psychology

Efficient environmental search is an important and adaptive everyday skill. A particular feature of theoretical interest is whether large-scale search is informed by the spatial statistics of the environment - probability cueing is a robust effect in two-dimensional visual search tasks, but studies of large-scale search have generated equivocal findings. Here, we examined whether sensitivity to a statistical cue specified within an allocentric reference frame is modulated by the presence and location of environmental landmarks. Participants explored fully immersive virtual environments, wherein they were presented with an array of locations (columns) and required to search them for a hidden target …

Minutes (1-16-2026), California State University, San Bernardino - Associated Students, Incorporated

Associated Students, Incorporated records

No abstract provided.

Elevated Trna Halves In Olfactory Epithelial Cells Of Patients With Schizophrenia, Justin T. Gumas, Megumi Shigematsu, Karin E. Borgmann-Winter, C. G. Hahn, Yohei Kirino

Computational Medicine Center Faculty Papers

Schizophrenia patients' olfactory epithelial cells contain abundant immune-activating tRNA fragments, linking small RNA biology to inflammation and suggesting avenues for diagnostics.

Human Capital And Development, Philippe Aghion, Ingvild Almås, Costas Meghir

Cowles Foundation Discussion Papers

Human capital is central to efforts to promote growth, convergence, and the elimination of poverty. Drawing on seminal macroeconomic frameworks by Nelson-Phelps, Lucas, and subsequent developments, alongside macro and microeconomic evidence, the chapter examines the role of human capital in driving innovation and growth, emphasizing how different types of human capital matter at different stages of development, and discussing obstacles to accumulation and evidence from policy interventions.

Considerations When Venturing Into Community Engagement With Those Who Struggle To Access Advice Or Care, Ruth Potterton, Abigail Nelder, Karen Burn

Peninsula Dental School

No abstract provided.

Book Review: A Day In September: The Battle Of Antietam And The World It Left Behind, Wylie W. Johnson

Parameters Bookshelf – Online Book Reviews

Author: Stephen Budiansky

Reviewed by: Dr. Wylie W. Johnson, US Army War College Class of 2010

A Day in September: The Battle of Antietam and the World It Left Behind analyzes the battle’s “Revolution in Military Affairs” and how it radically changed the United States and the world. It focuses on technologies, personalities, military doctrine, nongovernmental organizations, medical advances, international intrigue, and politics.

Michael West V. Kevin Matthews

2026 Decisions

USDC for the District of New Jersey

Distribution System Reliability Evaluation Considering Protection Coordination Using Petri Nets, Rani Kumari, Bhukya Krishna Naick

Turkish Journal of Electrical Engineering and Computer Sciences

Maintaining reliable and high-quality power delivery becomes increasingly complex with expanding power grids. The lack of protection coordination poses a significant threat, compromising overall system reliability. This research addresses this challenge by proposing a method for coordinating protective devices within the distribution system, specifically during network faults. The proposed approach utilizes a stochastic timed Petri net (STPN) based methodology to model protective device coordination across various fault scenarios. This technique effectively captures the dynamic behavior and interactions of protective equipment, allowing for the anticipation of potential disturbances. This proactive insight facilitates preventative measures to address prewarning situations, thereby preventing cascading …

A Programmable Genetic Platform For Engineering Noninvasive Biosensors, Asish N Chacko, Kaamini M Dhanabalan, Jinyang Wan, Roy Chien, Nolan T Anderson, Binzhi Xu, Katie Pham, Ritu Tiwari, Arnab Mukherjee

Faculty, Staff and Student Publications

Creating genetic sensors for noninvasive visualization of biological activities in optically opaque tissues holds immense potential for basic research and the development of genetic and cell-based therapies. Magnetic resonance imaging (MRI) stands out among deep tissue imaging methods for its ability to generate high-resolution images without ionizing radiation. However, the adoption of MRI as a mainstream biomolecular technology has been hindered by the lack of adaptable methods to link molecular events with genetically encodable contrast. Here, we introduce modular aquaporin-based protease-activatable probes for enhanced reporting (MAPPER), a platform for the systematic creation of genetic sensors for MRI. To develop MAPPER, …

Exploring The Experience Of Co-Designing Mental Health Services In The National Health Service As An Expert By Experience, Annabelle Mccall, Peta Temple, River Rose, Pete Keohane, Lealah Hewitt-Johns

School of Psychology

PurposeThe number of Experts by Experience (EbE) working in mental health services has grown in recent years. The National Health Service (NHS) five-year plan states EbE should be used across different levels, including service delivery, design and commissioning. While current research explores the role of EbE in service delivery, little is known about their experiences of co-designing services. This study aims to explore EbE experiences of co-designing NHS mental health services.Design/methodology/approachThis research used qualitative semi-structured interviews with ten participants who had worked on projects focused on co-designing NHS mental health services as an EbE. Data were analysed using reflexive thematic …

Butte Priority Soils Operable Unit (Bpsou) Data Summary Report (Dsr) Statement Of Authenticity Updates, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Prevalence Of Depression Among Doctors In General Hospitals Of Basrah City Center During The Covid-19 Pandemic, Riham Sabri Saleh, Amaleed Kadhum, Raya Habeeb Abdulimam

Iraqi National Journal of Medicine

Background: Depression is the most common mental disorder in community settings and a major cause of disability worldwide. In 1999, it was the fourth most common cause of disability globally, and by 2020, it is projected to become the second most common cause. Doctors, as the primary workforce in hospitals, endure significant emotional and physical stress, which may have been exacerbated by the COVID-19 pandemic. Aim: This study aimed to estimate the prevalence of depression among doctors during the COVID-19 pandemic and its risk factors. Methods: This descriptive cross-sectional study was conducted from February 1 to June 1, 2021. The …