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Community And Individual Risk Factors Associated With Tuberculosis Treatment Outcomes: Ca, Md, And Oh, [2017-2021]., Kadiatu Banjoko Jan 2026

Community And Individual Risk Factors Associated With Tuberculosis Treatment Outcomes: Ca, Md, And Oh, [2017-2021]., Kadiatu Banjoko

Walden Dissertations and Doctoral Studies

There are unsuccessful treatment outcomes with Tuberculosis (TB) disease, although effective therapies exist. This study aimed to identify predictors of unsuccessful treatment using the socioecological model. A quantitative cross-sectional study and multinomial logistic regression analysis were used to measure the associations between long-term care (LTC), homelessness, correctional facility, Human Immunodeficiency Virus (HIV), diabetes, excess alcohol, illicit drug use, and TB treatment outcomes of death, lost to follow-up, and treatment refusal. The sample consisted of 7,589 individuals aged 15 and older with pulmonary TB between 2017 and 2021, residing in California, Ohio, and Maryland. Findings indicated a correlation between community factors …


High Impact Service Learning: College Student Reflections On Out-Of-School Programming For Youth With Type 1 Diabetes, Eddie Hill, Ron Ramsing, Rowan Williams Jan 2026

High Impact Service Learning: College Student Reflections On Out-Of-School Programming For Youth With Type 1 Diabetes, Eddie Hill, Ron Ramsing, Rowan Williams

ACA National Camp Research Forum Abstracts

No abstract provided.


From Forest Aversion To Pro-Environmental Attitudes And Behaviors: Impacts Of A 3-Day Culturally Informed Camp, Candace Jones, Xiangyou Shen Jan 2026

From Forest Aversion To Pro-Environmental Attitudes And Behaviors: Impacts Of A 3-Day Culturally Informed Camp, Candace Jones, Xiangyou Shen

ACA National Camp Research Forum Abstracts

No abstract provided.


"Everyone Was Like Me": Summer Camp As An Affinity Group For Youth With Albinism, Maria Lepore-Stevens Jan 2026

"Everyone Was Like Me": Summer Camp As An Affinity Group For Youth With Albinism, Maria Lepore-Stevens

ACA National Camp Research Forum Abstracts

No abstract provided.


Managerial Approaches To Camp Staff Self-Care: Application Of The Perma Model, Megan H. Owens, Alexandra Skrocki, Melissa Van Scoy, Barry A. Garst, Tracey Gaslin Jan 2026

Managerial Approaches To Camp Staff Self-Care: Application Of The Perma Model, Megan H. Owens, Alexandra Skrocki, Melissa Van Scoy, Barry A. Garst, Tracey Gaslin

ACA National Camp Research Forum Abstracts

No abstract provided.


Summer Staff Burnout, Empathy, And Belongingness In Disease-Specific Camps, James Rujimora, Amanda Dediego, Ann Gillard Jan 2026

Summer Staff Burnout, Empathy, And Belongingness In Disease-Specific Camps, James Rujimora, Amanda Dediego, Ann Gillard

ACA National Camp Research Forum Abstracts

No abstract provided.


Tick Incidence Across Midwestern Summer Camps: Associations With Landscape Characteristics In Year 2 Of Fight The Bite, Alexandea Skrocki, Barry A. Garst, Tracey Gaslin Jan 2026

Tick Incidence Across Midwestern Summer Camps: Associations With Landscape Characteristics In Year 2 Of Fight The Bite, Alexandea Skrocki, Barry A. Garst, Tracey Gaslin

ACA National Camp Research Forum Abstracts

No abstract provided.


Assessing The Burden Of Care For Parents Whose Children Attend Diabetes Camp, Eddie Hill, Justin Haegele, Xihe Zhu, Ron Ramsing, Carla Cox Jan 2026

Assessing The Burden Of Care For Parents Whose Children Attend Diabetes Camp, Eddie Hill, Justin Haegele, Xihe Zhu, Ron Ramsing, Carla Cox

ACA National Camp Research Forum Abstracts

No abstract provided.


How Campers With Profound Intellectual And Multiple Disabilities And Their Camp Counselors Attune During A Medical Specialty Camp, Jonathan Gerth Jan 2026

How Campers With Profound Intellectual And Multiple Disabilities And Their Camp Counselors Attune During A Medical Specialty Camp, Jonathan Gerth

ACA National Camp Research Forum Abstracts

No abstract provided.


Validating The My View Youth Care And Engagement Scale For Pre-Camp Screening, Barry A. Garst, Alexandra Skrocki, John Hamilton, Tracey Gaslin Jan 2026

Validating The My View Youth Care And Engagement Scale For Pre-Camp Screening, Barry A. Garst, Alexandra Skrocki, John Hamilton, Tracey Gaslin

ACA National Camp Research Forum Abstracts

No abstract provided.


Creating Space For Childhood: Camp As A Source Of Play And Belonging For Youth From Families With Substance Disorders, Edmond P. Bowers, Theresa N. Melton, Brian J. Maus, Tori A. Garcia Jan 2026

Creating Space For Childhood: Camp As A Source Of Play And Belonging For Youth From Families With Substance Disorders, Edmond P. Bowers, Theresa N. Melton, Brian J. Maus, Tori A. Garcia

ACA National Camp Research Forum Abstracts

No abstract provided.


Exploring Leisure Attitutdes, Work-Leisure Similarity, And Staff Resilience, Daniela Berry, C. Scott Shafer, Daniel Pilgreen Jan 2026

Exploring Leisure Attitutdes, Work-Leisure Similarity, And Staff Resilience, Daniela Berry, C. Scott Shafer, Daniel Pilgreen

ACA National Camp Research Forum Abstracts

No abstract provided.


Bridging The Gap: Targeted Staff Training For Camps Serving Individuals With Disabilities, Bill Joe Averitt, Jo An Zimmerman-Somoza Jan 2026

Bridging The Gap: Targeted Staff Training For Camps Serving Individuals With Disabilities, Bill Joe Averitt, Jo An Zimmerman-Somoza

ACA National Camp Research Forum Abstracts

No abstract provided.


2026, Aca Camp Research Forum Book Of Abstracts, American Camp Association Jan 2026

2026, Aca Camp Research Forum Book Of Abstracts, American Camp Association

ACA National Camp Research Forum Abstracts

This book includes 20 abstracts that will be presented at the 2026 American Camp Association (ACA) Research Forum to be held during the ACA annual conference from February 17-20, 2026, in San Diego, California. Abstracts have been grouped into similar areas and will be presented across five verbal sessions (i.e., camper outcomes, specialty programming, camp staffing, camp administration, and medical/health for youth and families) and one poster session.


Assessing Abuse And Neglect In U.S. Nursing Homes: A Comparative Analysis Across Pre-, During, And Post-Pandemic Periods, Katherine Gane Jan 2026

Assessing Abuse And Neglect In U.S. Nursing Homes: A Comparative Analysis Across Pre-, During, And Post-Pandemic Periods, Katherine Gane

Theses and Dissertations

Nursing homes are among the most closely regulated providers in the U.S. healthcare system, with both federal and state agencies working together to monitor care and help protect residents. The COVID-19 pandemic, however, introduced unprecedented challenges for facilities and survey agencies alike, disrupting normal operations, limiting in-person visits, and temporarily shifting regulatory priorities. The purpose of this study was to examine how these pandemic-related disruptions were reflected in the severity and reporting patterns of substantiated abuse and neglect deficiencies in U.S. nursing homes. Using publicly available data from the Centers for Medicare & Medicaid Services (CMS), this study analyzed 39,607 …


Multilevel Analysis Of The Food And Physical Activity Environment And Adult Obesity Across U.S. Counties And States, Ann Mary Abraham, Michael D Swartz, Alexandra E Van Den Berg, Stephen H Linder Jan 2026

Multilevel Analysis Of The Food And Physical Activity Environment And Adult Obesity Across U.S. Counties And States, Ann Mary Abraham, Michael D Swartz, Alexandra E Van Den Berg, Stephen H Linder

Faculty, Staff and Student Publications

Adult obesity rates have risen steadily across the United States over the past decade, with more than 40% of adults affected. Persistent geographic and demographic disparities exist in obesity prevalence across the nation. While prior research has examined individual or environmental associated factors of obesity, limited studies have addressed both physical activity and food environments across the nation using multilevel approaches. This cross-sectional ecological study (2014-2024) used a two-level random intercept model to assess the association between county- and state-level factors and adult obesity prevalence across over 3000 U.S. counties nested within 51 states. County-level associated factors included food insecurity, …


Sga 57 Senate 2026-01-23 Minutes, Niu Student Government Association Senate Jan 2026

Sga 57 Senate 2026-01-23 Minutes, Niu Student Government Association Senate

Student Government Association Archives

No abstract provided.


Leader Perspectives From Policy To Practice: An Exploration Of Deiajb Accreditation Expectations In K-12 International Schools, Jennifer Lea Garzia Jan 2026

Leader Perspectives From Policy To Practice: An Exploration Of Deiajb Accreditation Expectations In K-12 International Schools, Jennifer Lea Garzia

LMU Theses and Dissertations

In recent years, various school accreditation bodies have incorporated new standards and processes that focus on diversity, equity, inclusion, access, justice, and belonging (DEIAJB). Yet, how DEIAJB expectations are perceived and implemented remains underexplored. This study examines the perceptions of international school leaders in Brazil and Italy, and how they interpret and enact DEIAJB school accreditation expectations. In this qualitative exploratory study, ten international school leaders were interviewed. Guided by Shields’ Transformative Leadership Theory (2009), data were collected through semi-structured interviews and were analyzed using thematic coding. Findings revealed that leaders viewed DEIAJB accreditation expectations as a legitimizing framework that …


Clinical Workflow Of Spine Stereotactic Radiotherapy And Radiosurgery: Insights From A Single-Institution Physics Perspective, Dennis Mackin, Gizem Cifter, Yana Zlateva, Jihong Wang, Yao Ding, Muhammad Shafiq Ul Hassan, Zhiheng Wang, Parmeswaran Diagaradjane, Fada Guan, Travis C Salzillo, Shane Krafft, Jing Li, Martin C Tom, Amol J Ghia, Tina Marie Briere Jan 2026

Clinical Workflow Of Spine Stereotactic Radiotherapy And Radiosurgery: Insights From A Single-Institution Physics Perspective, Dennis Mackin, Gizem Cifter, Yana Zlateva, Jihong Wang, Yao Ding, Muhammad Shafiq Ul Hassan, Zhiheng Wang, Parmeswaran Diagaradjane, Fada Guan, Travis C Salzillo, Shane Krafft, Jing Li, Martin C Tom, Amol J Ghia, Tina Marie Briere

Faculty, Staff and Student Publications

Spine stereotactic radiotherapy and radiosurgery (SSRS) techniques, encompassing both fractionated stereotactic treatments and single-fraction radiosurgery, are widely used for the management of spinal metastases due to their ability to deliver highly conformal radiation while limiting dose to adjacent critical structures. Clinical outcomes following SSRS, including durable local control and acceptable toxicity, have been reported previously in multiple institutional series. In this manuscript, we describe the clinical workflow used to deliver SSRS at a high-volume academic center, with emphasis on the medical physics processes that support routine clinical practice. Key elements of the workflow include patient selection, treatment region-specific immobilization, CT …


Women In Law And The Draft, Thomas Helgerman, Benjamin David Pyle Jan 2026

Women In Law And The Draft, Thomas Helgerman, Benjamin David Pyle

Faculty Scholarship

Between 1964 and 1973, women’s representation in full-time law school programs rose fivefold, from 3.7% to 20.1%. This paper examines whether Vietnam War draft policy contributed to this increase. In 1968, men enrolled in law school lost eligibility for 2-S student deferments, threatening law schools’ tuition revenues and incentivizing schools to admit more women to stabilize enrollment. To test this mechanism, we construct a school-by-year dataset of enrollment counts split by women/men and full-time/part-time status. Using a uniform adoption difference-in-differences design, we find that women’s representation rises by 2 percentage points in full-time programs relative to part-time programs (which were …


Restoration Enhances Carbon Storage In Mangroves After Hurricane Impacts, Robert Puschendorf Jan 2026

Restoration Enhances Carbon Storage In Mangroves After Hurricane Impacts, Robert Puschendorf

School of Biological and Marine Sciences

Mangroves are globally important blue-carbon ecosystems, yet their resilience isthreatened by extreme weather events and hydrological alterations. Insoutheastern Mexico, a large mangrove die-off occurred in 1995 followingHurricane Roxanne and Tropical Storm Opal, linked to storm-surge–drivenhypersalinity, sedimentation, and prolonged flooding. In 2005, an ecologicalrestoration program was launched in the Términos Lagoon region, focusing onhydrological rehabilitation and reforestation with Avicennia germinans. Fourteenyears later, we assessed ecosystem recovery by quantifying total ecosystemcarbon stocks (TECS), defined as the sum of 0–50-cm soil organic carbon andtree biomass carbon, across conserved, degraded, and restored sites, and byreconstructing vegetation cover dynamics from multi-decadal satellite imagery(1984–2023). TECS differed …


Transforming Dental Education Through Lived Experiences, Casper Jonker, Alex Cresswell-Boyes, Wendy Smith Jan 2026

Transforming Dental Education Through Lived Experiences, Casper Jonker, Alex Cresswell-Boyes, Wendy Smith

Peninsula Dental School

No abstract provided.


Intestinal Epithelial Tlr5 Signaling Promotes Barrier-Supportive Macrophages, Ming-Ting Tsai, Ryann Callaghan, Charles Ng, Lisette Peres-Tintin, Dean B Matthews, Nikketa Stanford, Karuna Ganesh, Mary K Estes, Gretchen E Diehl Jan 2026

Intestinal Epithelial Tlr5 Signaling Promotes Barrier-Supportive Macrophages, Ming-Ting Tsai, Ryann Callaghan, Charles Ng, Lisette Peres-Tintin, Dean B Matthews, Nikketa Stanford, Karuna Ganesh, Mary K Estes, Gretchen E Diehl

Faculty, Staff and Students Publications

Intestinal macrophages are essential for epithelial barrier repair. In homeostasis, macrophages are continuously replenished by recruitment of circulating CCR2+ monocytes into the intestinal lamina propria. This requires the commensal microbiota, however, the specific microbial factors and downstream host pathways that coordinate macrophage replenishment are inadequately understood. Here, we show that colonization with an E. coli isolate increased CCR2+ macrophages in the intestine and ameliorated pathology in a colitis model. Using human colonic organoids, we showed E. coli colonization induced CCL2 secretion by intestinal epithelial stem cells which promoted monocyte migration. In vivo, protection was abolished in the absence of epithelial …


Hiv Vpr Induces Demethylation Of The Snca Antisense Promoter, Leading To Neurocognitive Impairment, Maryline Santerre, Ying Wang, Daniel Kalamarides, Jin Park, Lynn G Kirby, Jeannie Chin, Jaroslav Jelinek, Natalia Shcherbik, Bassel E Sawaya Jan 2026

Hiv Vpr Induces Demethylation Of The Snca Antisense Promoter, Leading To Neurocognitive Impairment, Maryline Santerre, Ying Wang, Daniel Kalamarides, Jin Park, Lynn G Kirby, Jeannie Chin, Jaroslav Jelinek, Natalia Shcherbik, Bassel E Sawaya

Faculty, Staff and Students Publications

Human immunodeficiency virus type 1 (HIV-1) alpha-synuclein (α-Syn) aggregation is a hallmark of neurodegenerative diseases. Accumulation and aggregation of α-Syn are often observed in individuals with HIV-1 cognitive impairments. The direct mechanistic link between α-Syn dysregulation and HIV-associated neurocognitive disorders (HAND) remains unclear. Emerging evidence suggests that epigenetic changes, particularly deoxyribonucleic acid (DNA) demethylation, influence α-Syn regulation. We show that the HIV-1 protein viral protein R (Vpr) demethylates the antisense promoter within intron 1 of the alpha-synuclein gene (SNCA), potentially contributing to increased α-Syn expression. Elevated α-Syn promotes aggregation, causing synaptic dysfunction and impaired mitochondrial transport. These processes contribute to …


Women With Moderate Anaemia Prior To Conception Benefited Most From Nutrition Interventions: A Secondary Analysis Of The Women First Preconception Maternal Nutrition Trial, Sumera Aziz Ali, Ka Kahe, Jeanine Genkinger, Linda Valeri, Sarah Saleem, Saleem Jessani, Robert Goldenberg, Jamie Westcott, Jennifer Kemp, Ana Garces, Lester Figueroa, Shivaprasad Goudar, Sangappa Dhaded, Richard Derman, Antoinette Tshefu Kitoto, Adrien Lokangaka, Melissa Bauserman, Elizabeth Mcclure, Marion Koso-Thomas, Louise Kuhn, Nancy Krebs Jan 2026

Women With Moderate Anaemia Prior To Conception Benefited Most From Nutrition Interventions: A Secondary Analysis Of The Women First Preconception Maternal Nutrition Trial, Sumera Aziz Ali, Ka Kahe, Jeanine Genkinger, Linda Valeri, Sarah Saleem, Saleem Jessani, Robert Goldenberg, Jamie Westcott, Jennifer Kemp, Ana Garces, Lester Figueroa, Shivaprasad Goudar, Sangappa Dhaded, Richard Derman, Antoinette Tshefu Kitoto, Adrien Lokangaka, Melissa Bauserman, Elizabeth Mcclure, Marion Koso-Thomas, Louise Kuhn, Nancy Krebs

Global Health Articles

INTRODUCTION: The Women First (WF) Preconception Maternal Nutrition trial found greater benefits of small-quantity lipid-based nutrient supplements (SQ-LNS) for intrauterine growth among anaemic versus non-anaemic women at preconception. We investigated whether the benefits of SQ-LNS in improving markers of intrauterine growth occurred evenly across the mild to moderate spectrum of pre-pregnancy anaemia.

METHODS: We analysed WF data (n=2443 maternal-newborn dyads) from Pakistan, India, Guatemala and the Democratic Republic of Congo. Women received SQ-LNS either ≥3 months preconception through pregnancy (Arm 1); starting in the late first trimester (Arm 2); or not at all (Arm 3: control), with all supplementations discontinued …


Using The Linear References From The Pangenome To Discover Missing Autism Variants, Yang Sui, Jiadong Lin, Michelle D Noyes, Youngjun Kwon, Isaac Wong, Nidhi Koundinya, William T Harvey, Mei Wu, Kendra Hoekzema, Katherine M Munson, Gage H Garcia, Jordan Knuth, Julie Wertz, Tianyun Wang, Kelsey Hennick, Druha Karunakaran, Rafael A Polo Prieto, Rebecca Meyer-Schuman, Fisher Cherry, Davut Pehlivan, Bernhard Suter, Jonas A Gustafson, Danny E Miller, Human Pangenome Reference Consortium (Hprc), Hanna Berk-Rauch, Tomasz J Nowakowski, Aravinda Chakravarti, Huda Y Zoghbi, Evan E Eichler Jan 2026

Using The Linear References From The Pangenome To Discover Missing Autism Variants, Yang Sui, Jiadong Lin, Michelle D Noyes, Youngjun Kwon, Isaac Wong, Nidhi Koundinya, William T Harvey, Mei Wu, Kendra Hoekzema, Katherine M Munson, Gage H Garcia, Jordan Knuth, Julie Wertz, Tianyun Wang, Kelsey Hennick, Druha Karunakaran, Rafael A Polo Prieto, Rebecca Meyer-Schuman, Fisher Cherry, Davut Pehlivan, Bernhard Suter, Jonas A Gustafson, Danny E Miller, Human Pangenome Reference Consortium (Hprc), Hanna Berk-Rauch, Tomasz J Nowakowski, Aravinda Chakravarti, Huda Y Zoghbi, Evan E Eichler

Duncan NRI Faculty and Staff Publications

To better understand large-effect pathogenic variation associated with autism, we generated long-read sequencing (LRS) data to construct phased and near-complete genome assemblies (average contig N50 = 43 Mbp, QV = 56) for 189 individuals from 51 families with unsolved cases. We applied read- and assembly-based strategies to facilitate comprehensive characterization of de novo mutations, structural variants (SVs), and DNA methylation. Using LRS pangenome controls, we efficiently filtered >97% of common SVs exclusive to 87 offspring. We find no evidence of increased autosomal SV burden for probands when compared to unaffected siblings yet observe a suggestive trend toward an increased SV …


Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin Jan 2026

Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin

Faculty, Staff and Students Publications

Adult mammalian hearts exhibit limited regenerative capacity because of the restricted renewal of cardiomyocytes. Recent studies reveal that mammalian hearts exhibit transient regenerative potential within a short time frame after birth, suggesting a regulatory mechanism that prevents adult hearts from initiating a regenerative response to cardiac injury. Here, we discovered that an active form of YAP, named YAP6SA, which is not inhibited by the Hippo signaling pathway and does not interact with TEADs, induces cardiomyocyte cell cycle reentry. In addition, YAP6SA interacts with scaffold protein MPDZ to regulate Rho GTPases and promote cell cycle progression in cardiomyocytes (CMs). Importantly, YAP6SA …


De Novo Variants In The Splicing Factor Gene Sf3b1 Are Associated With Neurodevelopmental Disorders, Kevin Uguen, Tiffany Bergot, Marie-Pier Scott-Boyer, Solène Chapalain, Camille Desdouets, Séverine Commet, Changlian Zhu, Yiran Xu, Yangong Wang, Tony Roscioli, Frederic Tran-Mau-Them, Laurence Faivre, Julien Maraval, Julian Delanne, Anne-Sophie Denommé-Pichon, Antonio Vitobello, Céline Jost, Marc Planes, Susan Hiatt, Patricia Wheeler, Claudia Gonzaga-Jauregui, Heng Wang, Baozhong Xin, Valerie Sency, Michael C Kruer, Somayeh Bakhtiari, Patrick Sulem, Cynthia Curry, Trine Prescott, Gertrud Strobl-Wildemann, Theresa Brunet, Martine Doco Fenzy, Thomas Courtin, Céline Poirsier, Trine Bjørg Hammer, Christina D Fenger, Melissa Macpherson, Kosuke Izumi, Jacqueline Leonard, Dong Li, Elaine H Zackai, Ian A Glass, Scott Ward, Philippe M Campeau, Maria Carla Hermida Borroto, Laurence Le Moigno, Hilde Van Esch, Liesbeth De Waele, Daniel G Calame, James R Lupski, Giulia Barcia, Cristina Peduto, Pauline Planté-Bordeneuve, Lucie Dupuis, Roberto Mendoza-Londono, Dimitri J Stavropoulos, Jennifer Gillibert-Duplantier, Thomas Besnard, Laura Do Souto Ferreira, Benjamin Cogné, Stéphane Bézieau, Arnaud Droit, Laurent Corcos, Eric Lippert, Claude Férec, Sebastien Küry, Delphine G Bernard Jan 2026

De Novo Variants In The Splicing Factor Gene Sf3b1 Are Associated With Neurodevelopmental Disorders, Kevin Uguen, Tiffany Bergot, Marie-Pier Scott-Boyer, Solène Chapalain, Camille Desdouets, Séverine Commet, Changlian Zhu, Yiran Xu, Yangong Wang, Tony Roscioli, Frederic Tran-Mau-Them, Laurence Faivre, Julien Maraval, Julian Delanne, Anne-Sophie Denommé-Pichon, Antonio Vitobello, Céline Jost, Marc Planes, Susan Hiatt, Patricia Wheeler, Claudia Gonzaga-Jauregui, Heng Wang, Baozhong Xin, Valerie Sency, Michael C Kruer, Somayeh Bakhtiari, Patrick Sulem, Cynthia Curry, Trine Prescott, Gertrud Strobl-Wildemann, Theresa Brunet, Martine Doco Fenzy, Thomas Courtin, Céline Poirsier, Trine Bjørg Hammer, Christina D Fenger, Melissa Macpherson, Kosuke Izumi, Jacqueline Leonard, Dong Li, Elaine H Zackai, Ian A Glass, Scott Ward, Philippe M Campeau, Maria Carla Hermida Borroto, Laurence Le Moigno, Hilde Van Esch, Liesbeth De Waele, Daniel G Calame, James R Lupski, Giulia Barcia, Cristina Peduto, Pauline Planté-Bordeneuve, Lucie Dupuis, Roberto Mendoza-Londono, Dimitri J Stavropoulos, Jennifer Gillibert-Duplantier, Thomas Besnard, Laura Do Souto Ferreira, Benjamin Cogné, Stéphane Bézieau, Arnaud Droit, Laurent Corcos, Eric Lippert, Claude Férec, Sebastien Küry, Delphine G Bernard

Faculty, Staff and Students Publications

SF3B1 is an essential and ubiquitous splicing factor that plays a pivotal role in the early steps of pre-mRNA splicing. Recurrent somatic missense mutations in SF3B1 are frequent in cancers, but no constitutional variant has been reported so far. We describe here a cohort of 26 individuals with neurodevelopmental disorders, harbouring SF3B1 constitutional heterozygous variants that appeared mostly de novo. Patients present with a global developmental delay, associated with variable neurological and facial dysmorphic traits. A dichotomy may emerge between patients harbouring predicted loss of function (n = 9) and missense variants (n = 17), the latter being associated with …


Scaling Pedestrian Crossing Analysis To 100 U.S. Cities Via Ai-Based Segmentation Of Satellite Imagery, Marcel E. Moran, Arunav Gupta, Jiali Qian, Debra Laefer Jan 2026

Scaling Pedestrian Crossing Analysis To 100 U.S. Cities Via Ai-Based Segmentation Of Satellite Imagery, Marcel E. Moran, Arunav Gupta, Jiali Qian, Debra Laefer

Faculty Research, Scholarly, and Creative Activity

Accurately measuring street dimensions is essential to evaluating how their design influences both travel behavior and safety. However, gathering street-level information at city-scale with precision is difficult given the quantity and complexity of urban intersections. To address this challenge in the context of pedestrian crossings — a crucial component of walkability — we introduce a scalable and accurate method for automatically measuring crossing distance at both marked and unmarked crosswalks, applied to America’s 100 largest cities. First, OpenStreetMap coordinates were used to retrieve satellite imagery of intersections throughout each city — totaling roughly three million images. Next, Meta’s Segment Anything …


Evaluation Of Vaping Cessation Infographics Among E-Cigarette Users: A Cross-Sectional, Mixed-Methods Study, Hongying Daisy Dai, Chenxi Shi, Sara Reyes, Summer Woolsey Jan 2026

Evaluation Of Vaping Cessation Infographics Among E-Cigarette Users: A Cross-Sectional, Mixed-Methods Study, Hongying Daisy Dai, Chenxi Shi, Sara Reyes, Summer Woolsey

Student Publications

Introduction: This rise in vaping has become a significant public health concern. This mixed-methods study aims to assess the impact of vaping cessation infographics on different cessation motivation and gather feedback regarding how the infographic could be further improved.

Methods: Current e-cigarette users completed an online cross-sectional survey in January 2022 through Prolific®. Participants evaluated a vaping cessation infographic. Eligible participants were adults aged 19-64 years, US residents, fluent in English, and current e-cigarette users. Participants completed a questionnaire with questions regarding demographics, e-cigarette use, and assessment of the liking of infographics. Poisson regressions were conducted to assess the associations …