Digital Commons Network^™

Pericardial Effusion, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Kawasaki Disease, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Effects Of A Carbohydrate + Caffeine Beverage On Game Performance, Blood Glucose And Perceived Effort In Collegiate Women Soccer Players, Andrew Jagim, Abby Ambrosius, Makenna Carpenter, Joesi Krieger, Lochlan Charley, Jennifer Fields, Margaret T. Jones, Chad Kerksick

Faculty Scholarship

Carbohydrate availability and caffeine ingestion have been shown to elicit improvements in performance independently of one another. The purpose of the study was to examine the effect of a carbohydrate + caffeine beverage on performance and perceived effort in soccer players. Forty-three collegiate women’s soccer athletes were recruited to participate during a single day of simulated match play, in which each team played once. Athletes consumed either a carbohydrate + caffeine (Experimental) beverage or a control (Control) beverage (flavored water) during half-time in a double-blind, placebo-controlled, randomized control trial design. Prior to and after each game, Ratings of Perceived Exertion …

International Society Of Sports Nutrition Position Stand: Effects Of Dietary Antioxidants On Exercise And Sports Performance, Drew E. Gonzalez, Broderick L. Dickerson, Brandon M. Roberts, Jennifer A. Kurtz, Hunter S. Waldman, Adam M. Gonzalez, Matthew J. Mcallister, Jeffery L. Heileson, Richard J. Bloomer, Shawn M. Arent, Darren G. Candow, Jeffrey R. Stout, Karen A. Hecht, Bill Campbell, Chad Kerksick, Douglas Kalman, Jose Antonio, Richard B. Kreider

Faculty Scholarship

Following a comprehensive review, the International Society of Sports Nutrition (ISSN) has developed an official position on the role of dietary antioxidants in exercise and sport. Antioxidants play a complex, context-dependent role in vivo; they can facilitate recovery from exercise but may also hinder training adaptations when consumed at supraphysiological doses. While endogenous antioxidant systems can effectively maintain redox balance, dietary sources, particularly whole foods, can help mitigate excessive oxidative stress following intense/heavy training or inadequate recovery. The influence of dietary antioxidants depend on timing, dosage, type, and individual factors. The ISSN’s official position encompasses the following: (1) Redox balance …

Teaching Professional Resistance, Darlene Peterson Md

Faculty Development Tips

No abstract provided.

Inflection Points In Academic Career Trajectories: Statistical Modeling And Interactive Visualization, Aicha Malouche

Theses

This thesis examines the temporal structure of academic career trajectories, with a particular focus on identifying non-linear patterns of research productivity and moments of maximum acceleration in scientific impact. Situated within the broader context of bibliometric evaluation, the study responds to long-standing limitations of aggregate and linear career models that obscure heterogeneity across disciplines and national research systems. Drawing on theories of cumulative advantage, life-cycle productivity, and structural stratification, the research seeks to clarify how and when elite researchers experience peak growth in impact over the course of their careers. The study is guided by four research questions: (1) when …

Social Media Monitoring And The Admissions Process: A Study Of College Admissions Officers' Use Of Social Media In Undergraduate Application Review, Rachel Karpeles

Graduate Student Dissertations, Theses, Capstones, and Portfolios

This study explored the evolving role of social media in college admissions, focusing on the perceptions and practices of admissions professionals following the U.S. Supreme Court’s 2023 decision on Affirmative Action. The research, utilizing a descriptive design, employed a 31-question anonymous survey administered to a convenience sample of 532 admissions representatives. The findings directly contradict the public and media narrative by revealing a profound paradox: while social media monitoring is not a widespread professional practice, its impact on admissions outcomes for a notable portion of applicants is demonstrably significant.

The study found a majority of respondents believe evaluating applicants based …

A Comparative Analysis Of U.S. And Mexico’S Migration Policy From 2009 To 2025: How Their Approaches Shape And Constrain Each Other’S Policy Choices, Viviana Adame

Senior Theses

The long history of movement across the U.S.–Mexico border has made migration one of the main issues shaping their bilateral relationship. This thesis examines how U.S. and Mexican migration policies from 2009 to 2025 affect and limit each other. Using the idea of migration diplomacy, it argues that migration is not just a domestic issue but a way both countries negotiate power and cooperation. The study compares six administrations: Obama, Trump, and Biden in the United States, and Calderón, Peña Nieto, and López Obrador in Mexico, through policy documents, data, and reports. It finds that the United States depends on …

Philippine Cultural Sovereignty: At Risk In The Hands Of Neocolonialism And The Ruling Class, Juliet Mary Atienza Romero

Senior Theses

As countries in the Global South continue to achieve recognized sovereignty, hegemonic powers become eager to find other methods of control, typically through the consolidation of political, economic, and cultural means. The furthering of post-colonial efforts is facilitated by the cooperation of domestic powers, whose personal aims of power align with imperial interests of colonial-like dominance. The interaction between neocolonialism and the ruling class theory may reveal a broader issue beyond the understanding of economic and cultural expansionism as defined by the colonial period. Further, the role of the education system and the projects of docility as used by the …

Learning From The Covid-19 Pandemic To Enhance Online Learning Based On A Qualitative Case Study On Motivation And Mental Health, Bernice Madrid, Claudia Pratesi

HSC Education Days

No abstract provided.

Life-Extending Interventions Do Not Necessarily Result In Compression Of Morbidity: A Case Example Offering A Robust Statistical Approach., Deependra K Thapa, Wasiuddin Najam, Erik S Parker, Xi Rita Wang, Daniel L Smith, Ufuk Beyaztas, James F Nelson, Steven N Austad, Gary Churchill, David B Allison

Faculty Research 2026

Despite extensive research on life-extending interventions, rigorous statistical techniques to determine their impact on compression of morbidity (CoM) are rarely used. We present a case example of an analytical method for examining the effect of life-extending dietary interventions on CoM by comparing the rates of decline in vitality and survival toward the end of life. Using data from previous experimental studies in mice, we calculated the average rate of vitality decline by fitting exponential decay models to individual vitality trajectories and compared this rate with the rate of survival decline estimated from Cox proportional hazards model. The results showed that, …

Nrn1 As A Therapeutic Target For Alzheimer's Disease., Derian A Pugh, Gregory Cary, Kelsey M Greathouse, Lauren C Nassour-Caswell, Emma L Hobby, Nicholas T Seyfried, Jeremy H Herskowitz

Faculty Research 2026

INTRODUCTION: Neuritin-1 (NRN1) was identified as a synaptic protein associated with cognitive resilience to Alzheimer's disease (AD).

METHODS: Target risk score and cell type expression profiles were generated for NRN1 using methods developed by the Emory-Sage-SGC-JAX Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) Center and Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD). Antibody characterization was conducted using Western blots and densitometry to assess the relative protein abundances of NRN1 in rodents, humans, and cell models.

RESULTS: NRN1 has a TREAT-AD target risk score of 3.29 out of 5. Based on single-nucleus RNA sequencing from SEA-AD, NRN1 expression …

Beyond The Streetlight: A Treat-Ad Perspective On Where To Find New Alzheimer's Targets., Gregory Cary, Jesse C Wiley, Gregory W. Carter, Allan I Levey

Faculty Research 2026

Despite extensive investments in Alzheimer's disease (AD) therapeutic development, progress toward effective interventions remains modest. The landscape of potential novel therapeutic strategies is rapidly growing, but prioritization, validation, and tools to advance targets to trial are lagging. The Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) consortium has integrated systems-level data from large-scale studies profiling thousands of human brains, yielding target-specific risk scores that partition disease risk into discrete biological domains and enable data-driven target interrogation. Here, we compared clinical trial targets with top-ranked TREAT-AD targets and found a limited overlap as well as differences in the biology …

The Scope And Impact Of Walking The Talk For Dementia 2024, Sherril B. Gelmon, Kate Irving, Walter Dawson, Jonathan Adrián Zegarra-Valdivia, Lingani Mbakile-Mahlanza, Fernando Aguzzoli-Peres

Institute on Aging Publications

Walking the Talk for Dementia (WTD) is a global educational initiative integrating a walk along the Camino de Santiago with a symposium to combat dementia stigma, raise awareness, and foster inclusion.

Hold Paramount The Health, Safety, And Welfare Of The Public And The Planet, Daniel B. Oerther

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

No abstract provided.

Persistent Chemicals In Particulate Matter (Pm) Near A Hazardous Waste Thermal Treatment Facility, Chuqi Guo, Martine E. Mathieu-Campbell, Thomas Blanchard, Lavrent Khachatryan, Md Abdullah Al-Mamun, Qingzhao Yu, Myron Lard, Oluwafeyikemi Ogunmusi, Brenda Vallee, Wilma Subra, Iriel Edwards, David Malone, Slawo Lomnicki, Stephania A. Cormier, Jennifer Richmond-Bryant

Faculty Publications

Colfax, an overburdened community in central Louisiana, hosts the last commercially-operated open-burn/open-detonation (OB/OD) hazardous waste thermal treatment facility in the United States. Until December 2023 when their permit disallowed OB/OD, the facility processed military waste, fireworks, propellants, soils excavated from Superfund sites, and other hazardous materials. This community-engaged study measured ambient fine particulate matter (PM2.5), environmentally persistent free radicals (EPFRs), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), and metals using two high-volume PM2.5 samplers deployed 1.2 mi and 9.0 mi from the facility from April, 2022 through February, 2023. Elevated PM2.5 concentrations were recorded at both sites during spring and summer 2022. …

Dynamical Analysis Of A Stochastic $Sei_{U}I_{R}Rs$ Epidemic Model With Vaccination And Log-Normal Ornstein-Uhlenbeck Process, Qun Liu

Faculty Publications

In this study, we develop and investigate a stochastic $SEI_{u}I_{r}RS$ (Susceptible-Exposed-Undetected infected-Detected infected-Recovered-Susceptible) epidemic model with vaccination of newborns and the disease transmission rate driven by a log-normal Ornstein-Uhlenbeck process. By establishing a series of Lyapunov functions, we derive sufficient conditions for persistence in the mean of the disease in the long term under the condition $\mathcal{R}_{0}>1$ and these criteria are applied to guarantee the existence of an invariant probability measure of the stochastic system. Subsequently, we also derive sufficient conditions for eradication of the disease when the parameters $\mathcal{R}_{0}< 1$ and $\mathcal{R}_{0}^{E}< 1$. Finally, two numerical examples are given to confirm the theoretical results. This work can help us implement interventions to regulate the disease dynamics.

Communication As Layered Architecture: Core Processing And Empathic Modulation, Griselda Poe

Publications and Research

This paper proposes a structural re-description of communication by separating Core processing from its social interface. Using the developmental sequence of Large Language Models (LLMs) as an external reference point, a layered architecture is identified, consisting of a foundational Core processing layer and a subsequent Empathic modulation layer.

The investigation begins with the observation that empathic signaling can obstruct rather than facilitate interaction for certain individuals. By examining the emergence of Base AI—Core processing prior to empathic adjustment—it is demonstrated that coherent, constraint-preserving interaction is possible without affective resonance.

Through this framework, existing cognitive theories and observed "deficits" are repositioned. …

International Arbitration & Artificial Intelligence: Opportunities,Challenges,And Evolving Regulations, Martínez Quintanilla, Javier Antonio

Santa Clara Journal of International Law

This paper provides a comprehensive analysis of the regulatory framework; the opportunities and the challenges associated with the use of artificial intelligence in international arbitration. First, it addresses relevant regulatory instruments such as the Guideline on the Use of AI in Arbitration of the Chartered Institute of Arbitrators (CIARB); the Guidelines on the Use of Artificial Intelligence in Arbitration of the Silicon Valley Arbitration and Mediation Center (SVAMC); the Principles Supporting the Use of AI in Alternative Dispute Resolution of the International Centre for Dispute Resolution(ICDR); the European Union Artificial Intelligence Act; and the New Task Force on AI in …

Phosphorus Adsorption And Desorption Characteristics On Micronutrient Doped Biochar, Moe Kikuchi '27

Annual Student Research Poster Session

The increasing global demand for food necessitates efficient agricultural practices; however, the overuse of phosphorus (P) fertilizers presents a major environmental concern. Advanced materials, including biochar, offer promising strategies for mitigating these effects. Biochar, a carbonaceous material derived from biomass, can be functionalized with micronutrients such as magnesium (Mg) or iron (Fe) to enhance its P adsorption and retention characteristics so that the ion-doped biochar could serve as a sustained nutrient release fertilizer besides improving soil health. This study investigated the adsorption and desorption behavior of dissolved P (200 µM/g and 400 µM/g) in three types of biochars: raw (BC), …

Rivers Reimagined: Floods, Droughts, And The Future Of Hydrologic Systems In Aotearoa, Ryan Anderson '26

Annual Student Research Poster Session

Hydroelectric power plays a crucial role in New Zealand’s renewable energy system and depends on consistent and reliable rainfall and river flow. This study analyzes hydrologic variability in two Wairoa River catchments in the Northland Region of New Zealand, the Mangahahuru River (Site 46674) and the Kaihu River at Gorge (Site 46611). Over four months, streamflow data provided by the University of Otago, Department of Geography was analyzed using R in RStudio to examine flood frequency, seasonal drought periods, and long-term flow trends. Both catchments were evaluated with approximately 95% completeness. The comparison in flow trends between the rivers highlights …

Effects Of Peripheral Sympathetic Denervation On Phytohemagglutinin (Pha) Induced Cutaneous Swelling In The Hock And Tail Of Mice, Ayusha Pokharel '27, Masyn Naegele '26

Annual Student Research Poster Session

The sympathetic nervous system (SNS) carries stress signals directly to the site of injury and activates the immune system via direct neuronal innervation or release of systemic hormones. 6-hydroxydopamine (6-OHDA) is a neurotoxin that causes denervation of the SNS by eliminating the peripheral nerve terminals, which are responsible for sending the stress signals. The effect of sympathetic denervation on the localized immune response is unexplored in the literature. Therefore, our study aims to investigate the effect of 6-OHDA-induced sympathetic denervation on local inflammation following phytohemagglutinin (PHA)-induced swelling. Even under resting circumstances, some baseline level of stress is communicated to the …

Investigating The Effects Of Novel Hexylamine Compounds On Hn6 Carcinoma Cell Survival, Lydia Neven '27, Dominic Pittman '26

Annual Student Research Poster Session

Cancer is a broad term encompassing hundreds of distinct diseases, each arising from unique genetic and environmental factors. Because of this diversity, there is a continual need to develop new chemotherapies. Oral cancer, in particular, remains one of the most common cancers worldwide, yet effective therapeutic options for this malignancy remain limited. Although billions of dollars are invested annually in cancer drug discovery in the United States, the process of evaluating and advancing candidate compounds often represents a critical bottleneck, leading many promising therapies to be abandoned before their full potential is understood. In collaboration with the Hansen lab, we …

Afit By The Numbers, Fy25, Air Force Institute Of Technology

AFIT Documents

AFIT’s mission is to educate defense professionals to innovatively accomplish the deterrence and warfighting missions of the USAF and USSF. AFIT’s vision of leading defense-focused education, research and consultation to accelerate military superiority across all domains is accomplished through operationally relevant advanced academic education, research, and professional continuing education.

Human-Centered Leadership Coaching For School Redesign & Career Connected Learning, Monica White

Bank Street Education Center

Focusing on the Bank Street Principal Innovation Fellowship’s first cohort, this report examines how coaching supported principals as they implemented FutureReadyNYC, the district’s career-connected learning initiative. Through case studies of four principal-coach pairs, the report identifies an emerging leadership coaching model—including key principles, practices, and outcomes—that contributed to meaningful school-level progress and offers insights for school systems seeking to use coaching to strengthen principals’ capacity to lead complex change.

A Note On Sufficient Dimension Folding For Regression Mean Function With Categorical Predictors, Bilin Zeng, Akim Adekpedjou, Xuerong Meggie Wen

Mathematics and Statistics Faculty Research & Creative Works

Multi-dimensional arrays are referred to as tensors. Tensor-valued predictors are commonly encountered in modern biomedical applications, such as electroencephalogram (EEG), magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion-weighted MRI, and longitudinal health data. In survival analysis, it is both important and challenging to integrate clinically relevant information, such as gender, age, and disease state along with medical imaging tensor data or longitudinal health data to predict disease outcomes. Most existing higher-order sufficient dimension reduction regressions for matrix- or array-valued data focus solely on tensor data, often neglecting established clinical covariates that are readily available and known to have predictive value. …

Feasibility, Acceptability And Initial Efficacy Of A Community-Based Mental Health Literacy Program Delivered By Civil Society Organizations Among Adults In Kenya: A Quasi-Experimental Study, Patrick Mwangala, Venoranda Rebecca Kuboka, Nimo Sharif, Ann Karendi, Gideon Mbithi, Amina Abubakar

Institute for Human Development, East Africa

Mental health literacy (MHL) strategies are crucial for mental health promotion and prevention. This study aimed to determine the acceptability, feasibility, appropriateness and initial efficacy of an adapted MHL program in a community sample of adults in Kenya. This was a quasi-experimental pre-post study conducted from July 2023 through July 2024. The MHL program contained nine modules delivered over 3 days. Participants were assessed at baseline and immediately after the program. The primary outcomes were mental health knowledge and participants’ attitudes on mental health/illness. Secondary outcomes included depressive symptoms, anxiety symptoms, self-perceived social support, self-perceived wellbeing, MHL program acceptability, feasibility …

Patient, Family And Clinician Priorities For Critical Care Research In Asia And Africa: A James Lind Alliance Priority Setting Partnership Using Modified Delphi And Nominal Group Techniques, Ccaa Priority Setting Partnership Steering Group, Teddy Abonyo, Sumaiya Arfin, Diptesh Aryal, Abi Beane, Martina Borellini, Arjen Dondorp, Emma Donley, Punam Gautam, Tiffany Gooden

Anaesthesiology, East Africa

Background This James Lind Alliance (JLA) Priority Setting Partnership aimed to identify and prioritise unanswered questions important to adult patients, their families and health professionals with lived experience of critical care across Asia and Africa.

Methods Modified Delphi techniques were used to generate suggestions using an online survey. Following verification, literature review and content analysis, these suggestions were iteratively codified into emergent topics. Topics were presented in a second online survey for ranking, prior to an online workshop where nominal group technique was used to identify top priority questions across stakeholder groups. Surveys were disseminated using snowballing techniques.

Findings The …

The Illusion Of Justice: How Criminalizing Status Undermines The Rule Of Law, Luz M. Payán

Immigration Law Blog

In May of 2025, United States Senator Cornyn introduced the Justice for American Victims of Illegal Aliens Act. The Act creates an additional aggravating factor in determining whether to impose the death sentence. The aggravating factor would only be applicable when a noncitizen is found guilty of killing a United States citizen. This Article first argues that this Act would create grave constitutional concerns and severely undermine the rule of law. Next, this Article urges that, in order to truly promote public safety, our government should focus on policies meant to empower communities.

The Illusion Of Justice: How Criminalizing Status Undermines The Rule Of Law, Luz M. Payán

Immigration Law Blog

In May of 2025, United States Senator Cornyn introduced the Justice for American Victims of Illegal Aliens Act. The Act creates an additional aggravating factor in determining whether to impose the death sentence. The aggravating factor would only be applicable when a noncitizen is found guilty of killing a United States citizen. This Article first argues that this Act would create grave constitutional concerns and severely undermine the rule of law. Next, this Article urges that, in order to truly promote public safety, our government should focus on policies meant to empower communities.