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Barriers And Facilitators To The Completion Of Advance Directives In Healthy, Non-Healthcare Employed Adults Aged 45-65, Michael Lawrence Dion Mar 2022

Barriers And Facilitators To The Completion Of Advance Directives In Healthy, Non-Healthcare Employed Adults Aged 45-65, Michael Lawrence Dion

Theses

The Patient Self-Determination Act passed in 1991 requires staff in health care facilities, such as skilled nursing facilities, hospitals, home health services and primary care offices to ask patients about advanced directives. Despite this, actual completions of advance directives in America remain low. To determine the barriers and facilitators to the completion of advance directives in healthy, non-health care employed individuals aged 45-65. It is believed healthy individuals in this age group both desire the advance directive, and have strong opinions regarding their end of life preferences.


Level Of Comfort In Evaluating Older Patients Amongst Medical Students And Emergency Medicine Residents, Lily L. Berrin, Phraewa Thatphet, Anita N. Chary, Surriya C. Ahmad, Don Melady, Shan W. Liu Mar 2022

Level Of Comfort In Evaluating Older Patients Amongst Medical Students And Emergency Medicine Residents, Lily L. Berrin, Phraewa Thatphet, Anita N. Chary, Surriya C. Ahmad, Don Melady, Shan W. Liu

Journal of Geriatric Emergency Medicine

Introduction

As the population ages, emergency physicians must be better equipped to manage the complex needs of older patients. While geriatric core competencies have been developed for medical students and emergency medicine (EM) residents, little work has been done to evaluate EM trainees’ comfort with these competencies, or their interest in and barriers to learning more about Geriatric Emergency Medicine (GEM).

Methods

We conducted a cross-sectional study of EM residents and medical students in their clinical years of training with interest in EM. We used an online self-administered survey to evaluate trainees’ self-reported comfort with previously reported geriatric competency domains, …


Biomechanical Evaluation Over Level Ground Walking Of User-Specific Prosthetic Feet Designed Using The Lower Leg Trajectory Error Framework, Victor Prost, W. Brett Johnson, Jenny A. Kent, Matthew J. Major, Amos G. Winter V. Mar 2022

Biomechanical Evaluation Over Level Ground Walking Of User-Specific Prosthetic Feet Designed Using The Lower Leg Trajectory Error Framework, Victor Prost, W. Brett Johnson, Jenny A. Kent, Matthew J. Major, Amos G. Winter V.

Physical Therapy Faculty Research

The walking pattern and comfort of a person with lower limb amputation are determined by the prosthetic foot’s diverse set of mechanical characteristics. However, most design methodologies are iterative and focus on individual parameters, preventing a holistic design of prosthetic feet for a user’s body size and walking preferences. Here we refined and evaluated the lower leg trajectory error (LLTE) framework, a novel quantitative and predictive design methodology that optimizes the mechanical function of a user’s prosthesis to encourage gait dynamics that match their body size and desired walking pattern. Five people with unilateral below-knee amputation walked over-ground at self-selected …


Reducing Catheter-Associated Urinary Tract Infections: Beyond The Bundle, Deana Cirillo Mar 2022

Reducing Catheter-Associated Urinary Tract Infections: Beyond The Bundle, Deana Cirillo

Student Scholarly Projects

Practice Problem: Catheter-associated urinary tract infections (CAUTIs) are preventable but are still the most common healthcare-associated infection (HAI) worldwide, encumbering the health of patients and escalating financial burden on society (CDC, 2021; Shadle, 2021).

PICOT: In adult patients with spinal cord injury, does direct observation of urinary catheter insertion, compared to the standard of care, reduce the rate of catheter-associated urinary tract infections, within ten weeks of implementation?

Evidence: Multiple factors contribute to Healthcare-Associated Infections (HAIs), but hand hygiene is the most important prevention measure to decrease contact transmission (Gould et al., 2017). The Centers for Disease Control (CDC) clinical …


Nurse-Led At Home Management Of Patients With Covid-19, Sherry Clement, Barbara Hayes, Erica Sullivan, Kathleen Craig Mar 2022

Nurse-Led At Home Management Of Patients With Covid-19, Sherry Clement, Barbara Hayes, Erica Sullivan, Kathleen Craig

Covid-19 Webinars

This webinar demonstrates the process by which experienced Registered Nurses adapt and respond to a pandemic emergency, by implementing skills in care coordination, home safety assessments, patient education and caregiver support. Utilizing the transitional care model, Nurses implemented an effective and low-cost telephone-based approach, by assessing, coordinating, and evaluating patient needs, and making appropriate referrals when indicated.

Learning Outcomes:

1. Create an action plan within your facility to deal with an emergent event, utilizing the Coordinated Transitions of Care (C-TraC) model.​

2. Develop an algorithm for nurse implementation when caring for patients' with COVID- 19.

3. Demonstrate knowledge of the …


As-937-22 Resolution On New Degree Program For Masters Of Science In Statistics, Andrew Schaffner, Kelly Bodwin, John Walker, Statistics Department Mar 2022

As-937-22 Resolution On New Degree Program For Masters Of Science In Statistics, Andrew Schaffner, Kelly Bodwin, John Walker, Statistics Department

Academic Senate Resolutions

Approves the new degree program for final review by the Chancellor’s Office.


Executive Committee - Agenda 3/29/2022, Academic Senate Mar 2022

Executive Committee - Agenda 3/29/2022, Academic Senate

Academic Senate Agendas

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Mar 2022

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


Comparison Of Bioelectrical Impedance Analysis With Dxa In Adolescents With Cystic Fibrosis Before And After A Resistance Training Intervention, Clifton J Holmes, Susan B Racette, Leslie Symonds, Ana Maria Arbeláez, Chao Cao, Andrea Granados Mar 2022

Comparison Of Bioelectrical Impedance Analysis With Dxa In Adolescents With Cystic Fibrosis Before And After A Resistance Training Intervention, Clifton J Holmes, Susan B Racette, Leslie Symonds, Ana Maria Arbeláez, Chao Cao, Andrea Granados

Open Access Publications

BACKGROUND: The purpose of this pilot study was to compare body composition metrics obtained by two portable bioelectrical impedance analysis (BIA) devices with dual-energy X-ray absorptiometry (DXA) among adolescents with cystic fibrosis (CF) before and after a resistance exercise training program.

METHODS: Participants with CF were assessed using DXA, single-frequency BIA (SFBIA), and multiple-frequency BIA (MFBIA) to quantify percent body fat (%Fat), fat mass (FM), and fat-free mass (FFM) at baseline and after a home-based resistance training intervention comprised of 36, 1 h sessions completed in 12-14 weeks. Repeated measures analysis of variance, paired samples

RESULTS: Ten participants (15.8 ± …


Continuous Care Intervention With Carbohydrate Restriction Improves Physical Function Of The Knees Among Patients With Type 2 Diabetes: A Non-Randomized Study, Kade S Lyman, Shaminie J Athinarayanan, Amy L Mckenzie, Camy L Pearson, Rebecca N Adams, Sarah J Hallberg, James P Mccarter, Jeff S Volek, Stephen D Phinney, John P Andrawis Mar 2022

Continuous Care Intervention With Carbohydrate Restriction Improves Physical Function Of The Knees Among Patients With Type 2 Diabetes: A Non-Randomized Study, Kade S Lyman, Shaminie J Athinarayanan, Amy L Mckenzie, Camy L Pearson, Rebecca N Adams, Sarah J Hallberg, James P Mccarter, Jeff S Volek, Stephen D Phinney, John P Andrawis

Open Access Publications

BACKGROUND: In a previous study, we assessed a novel, remotely monitored carbohydrate restricted diet regimen including nutritional ketosis in patients with type 2 diabetes and reported significant improvements in weight, glycemic control, abdominal fat and inflammation from baseline to 2 years. Knee outcome measures were collected as a secondary outcome in the trial. This study aims to assess the effect of this intervention on knee functional scores and to identify if changes in weight, central abdominal fat (CAF), glycemic status and high sensitivity C-reactive protein (hsCRP) were associated with its improvement.

METHODS: This prospective analysis included continuous care intervention (CCI, …


Functions Of Adp-Ribose Transferases In The Maintenance Of Telomere Integrity, Daniela Muoio, Natalie Laspata, Elise Fouquerel Mar 2022

Functions Of Adp-Ribose Transferases In The Maintenance Of Telomere Integrity, Daniela Muoio, Natalie Laspata, Elise Fouquerel

Department of Biochemistry and Molecular Biology Faculty Papers

The ADP-ribose transferase (ART) family comprises 17 enzymes that catalyze mono- or poly-ADP-ribosylation, a post-translational modification of proteins. Present in all subcellular compartments, ARTs are implicated in a growing number of biological processes including DNA repair, replication, transcription regulation, intra- and extra-cellular signaling, viral infection and cell death. Five members of the family, PARP1, PARP2, PARP3, tankyrase 1 and tankyrase 2 are mainly described for their crucial functions in the maintenance of genome stability. It is well established that the most describedrole of PARP1, 2 and 3 is the repair of DNA lesions while tankyrases 1 and 2 are crucial …


Extending Psychological Reactance Theory To Include Denial Of Threat And Media Sharing Intentions As Freedom Restoration Behavior, Noel H. Mcguire, Hannah Ball Mar 2022

Extending Psychological Reactance Theory To Include Denial Of Threat And Media Sharing Intentions As Freedom Restoration Behavior, Noel H. Mcguire, Hannah Ball

Communication Faculty Articles and Research

This study extends psychological reactance theory by examining denial of a public health threat and resistance toward media sharing as two novel types of freedom restoration. Participants (N = 220) were randomly assigned to watch a video advocating COVID-19 guidelines and completed an online survey assessing corresponding perceptions and behavioral intentions. Results of structural equation modeling supported the two-step model of reactance: greater perceived freedom threat was related to greater reactance, which in turn was linked to lower intentions to comply with COVID-19 guidelines, lower intentions to share the video with one’s online social network, and greater denial of COVID-19 …


Prmt7 Ablation Stimulates Anti-Tumor Immunity And Sensitizes Melanoma To Immune Checkpoint Blockade, Nivine Srour, Oscar D Villarreal, Swanand Hardikar, Zhenbao Yu, Samuel Preston, Wilson H Miller, Magdelena M Szewczyk, Dalia Barsyte-Lovejoy, Han Xu, Taiping Chen, Sonia V Del Rincón, Stéphane Richard Mar 2022

Prmt7 Ablation Stimulates Anti-Tumor Immunity And Sensitizes Melanoma To Immune Checkpoint Blockade, Nivine Srour, Oscar D Villarreal, Swanand Hardikar, Zhenbao Yu, Samuel Preston, Wilson H Miller, Magdelena M Szewczyk, Dalia Barsyte-Lovejoy, Han Xu, Taiping Chen, Sonia V Del Rincón, Stéphane Richard

Faculty, Staff and Student Publications

Despite the success of immune checkpoint inhibitor (ICI) therapy for cancer, resistance and relapse are frequent. Combination therapies are expected to enhance response rates and overcome this resistance. Herein, we report that combining PRMT7 inhibition with ICI therapy induces a strong anti-tumor T cell immunity and restrains tumor growth in vivo by increasing immune cell infiltration. PRMT7-deficient B16.F10 melanoma exhibits increased expression of genes in the interferon pathway, antigen presentation, and chemokine signaling. PRMT7 deficiency or inhibition with SGC3027 in B16.F10 melanoma results in reduced DNMT expression, loss of DNA methylation in the regulatory regions of endogenous retroviral elements (ERVs) …


Ohio Anuran Gut Microbiomes, Serena Hoffman Mar 2022

Ohio Anuran Gut Microbiomes, Serena Hoffman

Undergraduate Honors Thesis Projects

Recent studies focusing on the skin and gut microbiome of vertebrates have found how important microbiomes are to maintaining host health. Understanding the role the gut microbiome plays to host health is of great importance for conservation. Less is known about the gut microbiome than the skin microbiome for amphibians. Literature is especially lacking for local Ohio anuran species. The purpose of this study was to establish the baseline composition of the gut microbiome for local Ohio anurans and to determine whether host species or habitat is the best predictor of gut microbiome composition. Tadpoles were collected from seven different …


Black Cemeteries Matter: The Erasure Of Historic Black Cemeteries In Polk County, Florida, Juliana C. Waters Mar 2022

Black Cemeteries Matter: The Erasure Of Historic Black Cemeteries In Polk County, Florida, Juliana C. Waters

USF Tampa Graduate Theses and Dissertations

In the past several years, the Tampa Bay area has experienced a reckoning with regard to the intentional erasure, destruction, and abandonment of historic African American cemeteries such as Zion Cemetery in Tampa or St. Matthews Baptist Church Cemetery in Clearwater. Scholars, journalists, community members, archaeologists, and others have contributed to a growing movement that aims to identify and document these sacred sites in an effort to prevent further destruction. In this vein, this project aimed to identify and record cemeteries in Polk County, examine the processes leading to the erasure of historic Black cemeteries, the history surrounding erasure on …


Minimum Clinically Important Difference Of The Social Functioning In Dementia Scale (Sf-Dem): Cross-Sectional Study And Delphi Survey, Tamara Levene, Gill Livingston, Sube Banerjee, Andrew Sommerlad Mar 2022

Minimum Clinically Important Difference Of The Social Functioning In Dementia Scale (Sf-Dem): Cross-Sectional Study And Delphi Survey, Tamara Levene, Gill Livingston, Sube Banerjee, Andrew Sommerlad

More Faculty of Health Research

Objectives Good social functioning is important for people living with dementia and their families. The Social Functioning in Dementia Scale (SF-DEM) is a valid and reliable instrument measuring social functioning in dementia. However the minimum clinically important difference (MCID) has not yet been derived for SF-DEM. This study aims to define the MCID for the SF-DEM. Design We used triangulation, incorporating data from a cross-sectional study to calculate the MCID using distribution-based and anchor-based methods, and a Delphi survey. Setting and participants The cross-sectional survey comprised 299 family carers of people with dementia. Twenty dementia experts (researchers, clinicians, family carers) …


Aging-Associated Changes In Motor Function Are Ovarian Somatic Tissue-Dependent, But Berm Cell And Estradiol Independent In Post-Reproductive Female Mice Exposed To Young Ovarian Tissue, Tracy L. Habermehl, Kaden B. Underwood, Kevin D. Welch, Steven P. Gawrys, Kate C. Parkinson, Augusto Schneider, Michal M. Masternak, Jeffrey Mason Mar 2022

Aging-Associated Changes In Motor Function Are Ovarian Somatic Tissue-Dependent, But Berm Cell And Estradiol Independent In Post-Reproductive Female Mice Exposed To Young Ovarian Tissue, Tracy L. Habermehl, Kaden B. Underwood, Kevin D. Welch, Steven P. Gawrys, Kate C. Parkinson, Augusto Schneider, Michal M. Masternak, Jeffrey Mason

Center for Integrated Biosystems Publications

A critical mediator of evolution is natural selection, which operates by the divergent reproductive success of individuals and results in conformity of an organism with its environment. Reproductive function has evolved to support germline transmission. In mammalian ovaries, this requires healthy, active gonad function, and follicle development. However, healthy follicles do not contribute to germline transmission in a dead animal. Therefore, support of the health and survival of the organism, in addition to fertility, must be considered as an integral part of reproductive function. Reproductive and chronological aging both impose a burden on health and increase disease rates. Tremors are …


Newsroom, Georgia Southern University Mar 2022

Newsroom, Georgia Southern University

Newsroom (2006-2023)

  • Jiann-Ping Hsu College of Public Health Establishes Development Council


Rehabilitation Sciences News, Georgia Southern University Mar 2022

Rehabilitation Sciences News, Georgia Southern University

Clinical Sciences: News & Publications (2018-2023)

  • The RiteCare Center Collects Over 1,000 Pairs of Shoes


Usability Studies In The Electronic Resource Lifecycle, Rachel E. Scott, Caitlin Harrington, Kenneth C. Haggerty Mar 2022

Usability Studies In The Electronic Resource Lifecycle, Rachel E. Scott, Caitlin Harrington, Kenneth C. Haggerty

Faculty and Staff Publications – Milner Library

The usability of e-resources and services contributes to library patrons’ use and satisfaction with them, which in turn affects library employees’ acquisition, provision of access, administration, support, and evaluation of e-resources. Librarians can integrate usability into the e-resource lifecycle in a variety of places and using numerous methods. This presentation provides an introduction to usability testing, highlights two usability case studies involving e-resources, and discusses how librarians might fruitfully incorporate usability methods throughout the e-resource lifecycle.


Minimum Clinically Important Difference Of The Social Functioning In Dementia Scale (Sf-Dem): Cross-Sectional Study And Delphi Survey, T Levene, G Livingston, S Banerjee, A Sommerlad Mar 2022

Minimum Clinically Important Difference Of The Social Functioning In Dementia Scale (Sf-Dem): Cross-Sectional Study And Delphi Survey, T Levene, G Livingston, S Banerjee, A Sommerlad

Peninsula Medical School

Objectives Good social functioning is important for people living with dementia and their families. The Social Functioning in Dementia Scale (SF-DEM) is a valid and reliable instrument measuring social functioning in dementia. However the minimum clinically important difference (MCID) has not yet been derived for SF-DEM. This study aims to define the MCID for the SF-DEM. Design We used triangulation, incorporating data from a cross-sectional study to calculate the MCID using distribution-based and anchor-based methods, and a Delphi survey. Setting and participants The cross-sectional survey comprised 299 family carers of people with dementia. Twenty dementia experts (researchers, clinicians, family carers) …


Understanding How Offending Prevalence And Frequency Change With Age In The Cambridge Study In Delinquent Development Using Bayesian Statistical Models, Julian Stander, David P. Farrington, Caroline Lubert Mar 2022

Understanding How Offending Prevalence And Frequency Change With Age In The Cambridge Study In Delinquent Development Using Bayesian Statistical Models, Julian Stander, David P. Farrington, Caroline Lubert

School of Engineering, Computing and Mathematics

ObjectivesTo provide a detailed understanding of how the prevalence and frequency of offending vary with age in the Cambridge Study in Delinquent Development (CSDD) and to quantify the influence of early childhood risk factors such as high troublesomeness on this variation.MethodsWe develop a statistical model for the prevalence and frequency of offending based on the hurdle model and curves called splines that allow smooth variation with age. We use the Bayesian framework to quantify estimation uncertainty. We also test a model that assumes that frequency is constant across all ages.ResultsFor 346 males from the CSDD for whom the number of …


The Role Of Health Kiosks: Scoping Review, Inocencio Daniel Maramba, Ray Jones, Daniela Austin, Katie Edwards, Edward Meinert, Arunangsu Chatterjee Mar 2022

The Role Of Health Kiosks: Scoping Review, Inocencio Daniel Maramba, Ray Jones, Daniela Austin, Katie Edwards, Edward Meinert, Arunangsu Chatterjee

School of Nursing and Midwifery

Background Health kiosks are publicly accessible computing devices that provide access to services, including health information provision, clinical measurement collection, patient self–check-in, telemonitoring, and teleconsultation. Although the increase in internet access and ownership of smart personal devices could make kiosks redundant, recent reports have predicted that the market will continue to grow. Objective We seek to clarify the current and future roles of health kiosks by investigating the settings, roles, and clinical domains in which kiosks are used; whether usability evaluations of health kiosks are being reported, and if so, what methods are being used; and what the barriers and …


Judicial Impartiality In The Judicial Council Act 2019: Challenges And Opportunities, Brian M. Barry Dr Mar 2022

Judicial Impartiality In The Judicial Council Act 2019: Challenges And Opportunities, Brian M. Barry Dr

Articles

The Judicial Council is tasked with promoting and maintaining high standards of judicial conduct. The Judicial Council Act 2019 identifies judicial impartiality as a principle of judicial conduct that Irish judges are required to uphold and exemplify. Despite its ubiquity, judicial impartiality is perhaps under-explained and under-examined.

This article considers the nature and scope of judicial impartiality in contemporary Irish judging. It argues that the Judicial Council ought to take a proactive, multi-faceted approach to promote and maintain judicial impartiality, to address contemporary challenges that the Irish judiciary face including increasingly sophisticated empirical research into judicial performance, the proliferation of …


Covid-19 Newsletter (Vol. 112), Center For Disaster Medicine, New York Medical College Mar 2022

Covid-19 Newsletter (Vol. 112), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.


Development Of Enhanced Algae Strains And Sustainable Cultivation Processes For Production Of Algal Lipids For Biofuels And Bioproducts, Enlin Lo Mar 2022

Development Of Enhanced Algae Strains And Sustainable Cultivation Processes For Production Of Algal Lipids For Biofuels And Bioproducts, Enlin Lo

USF Tampa Graduate Theses and Dissertations

The establishment of an algae industry is crucial for addressing global biofuel and bioproduct demand that meets the Sustainable Development Goals (SDG) worldwide. Photosynthetic microalgae are excellent sources for food, fiber, fuel, feed, and fertilizer, which are the 5Fs of the SDG. However, at present, algae-based materials are not cost-competitive or sufficiently sustainable. Improved productivity, lower cultivation cost, and reduced use of resources are required to transition from lab to industry, necessitating the development of superior strains that have high productivity and can tolerate environmental stress, such as temperature and salinity, so they can be cultivated at large scale outdoors …


Defining The Role Of Oxidized Mitochondrial Dna In Myelodysplastic Syndromes, Grace Anne Ward Mar 2022

Defining The Role Of Oxidized Mitochondrial Dna In Myelodysplastic Syndromes, Grace Anne Ward

USF Tampa Graduate Theses and Dissertations

Myelodysplastic Syndromes (MDS) are heterogeneous bone marrow (BM) failure malignancies characterized by constitutive innate immune activation, NLRP3 inflammasome (IFM) driven pyroptotic cell death, and the induction of interferon-stimulated genes (ISG). MDS often diagnostically resembles other hematologic disorders, as such, additional tools are needed for the discrimination from overlapping disorders. We observed that oxidized mitochondrial DNA (ox-mtDNA) is released upon cytolysis. We hypothesize that levels of ox-mtDNA are high in MDS, allowing us to use it as a diagnostic biomarker; and that cell free ox-mtDNA is contributing to feedforward BM failure.

ROC/AUC analysis demonstrated that ox-mtDNA is a sensitive and specific …


Exploring The Structure And Activity Of Metallo-Tetracyclines, Shahedul Islam Mar 2022

Exploring The Structure And Activity Of Metallo-Tetracyclines, Shahedul Islam

USF Tampa Graduate Theses and Dissertations

Copper as a key component of electron transport chain of eukaryotes is an essential transition metal ion. Copper homeostasis in mammals complex and tightly regulated. Its strong reactivity together with binding with biologically important chemicals can have important repercussions in human health and overall environment. Tetracycline as one of most abundantly used antibiotic of the world has become abundant in the environment as well. Herein in this dissertation we take the journey to explore the complexation of tetracycline with metals in the environment and the intricate interaction between copper and tetracycline by investigating their oxidative behavior once they are complexed. …


Individual Differences In Response To Hostile And Benevolent Sexism In A Stem Interview Context: The Moderating Role Of Behavioral Activation, Elizabeth Kiebel Mar 2022

Individual Differences In Response To Hostile And Benevolent Sexism In A Stem Interview Context: The Moderating Role Of Behavioral Activation, Elizabeth Kiebel

USF Tampa Graduate Theses and Dissertations

Women continue to face sexism in workplace contexts, especially those that are male dominated, such as science, technology, engineering, and mathematics (STEM). Yet, women often fail to confront the sexism they experience, despite confrontation being an effective way to cope with and prevent future harassment (Fitzgerald et al., 1995; Magley, 2002). To date, no one has assessed the potential moderating role of personality differences related to approach motivation on women’s confrontation of sexism. In this study, women were exposed to either a hostilely sexist or benevolently sexist question during a mock job interview that was purportedly being conducted as part …


Small Heat Shock Protein 22 Preserves Neuronal Function In A Murine Model Of Tauopathy, Santiago Rodriguez Ospina Mar 2022

Small Heat Shock Protein 22 Preserves Neuronal Function In A Murine Model Of Tauopathy, Santiago Rodriguez Ospina

USF Tampa Graduate Theses and Dissertations

Proteinopathies is a family of diseases associated with the pathological aggregation of protein. There are a multitude of proteinopathies, like tauopathy and synucleinopathy that contribute to neurodegenerative diseases like Alzheimer’s disease (AD), Creutzfeldt-Jakob, Pick’s disease, Frontotemporal dementia, and Parkinson’s disease (PD). Currently, one focus of research in the field is mitigating aggregation-prone proteins contributing to disease state. One method of targeting aggregation is the use of chaperones. Chaperones are molecular machinery that help maintain homeostasis in the cells, through various roles and mechanisms, one of those methods is to regulate protein aggregation. Chaperones can achieve this by affecting protein-protein interactions, …