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Management Of Severe Localized Periodontal Destruction Associated With A Cemental Defect: A Case Report, Nik Madihah Nik Azis, Nurulhuda Mohd

Journal of Dentistry Indonesia

This case involved the management of a possible cemental tear, which resulted in poor response to nonsurgical periodontal therapy. This case was managed by exploratory surgery, along with the intention to surgically reduce the periodontal pocket. Exploratory surgery revealed a localized cemental defect. The periodontium healed with pocket closure after exploratory surgery and open-flap debridement. The difficulty in clinically diagnosing a localized periodontal destruction and the lack of consensus on managing these cases were highlighted. The possibility of an undiagnosed cemental defect in a tooth with localized periodontitis should be considered in cases not responding to periodontal therapy.

Salivary Iga Depression In Drug-Influenced Gingival Enlargement Among Hypertensive Patients, Muhammad Annurdin Sabarudin, Haslina Taib, Wan Majdiah Wan Mohamad, Siti Lailatul Akmar Zainuddin, Wan Syamimee Wan Ghazali, Ahmad Azhar Misran

Journal of Dentistry Indonesia

Drug-influenced gingival enlargement (DIGE) among hypertensive patients is commonly associated with antihypertensive drugs such as calcium channel blockers (CCBs). Immune response alteration is one of the proposed mechanisms for DIGE. Immunoglobulin A (IgA) in saliva which involves in defense mechanism was shown to be affected in patients with DIGE. Objective: This study aimed to determine the association of salivary IgA level with DIGE. Methods: This cross-sectional study comprised 47 hypertensive patients who had consumed antihypertensive drugs for at least 3 months. Twenty-one (44.7%) males and 26 (55.3%) females had participated in this study. Data was analyzed using SPSS version 26.0. …

In Vitro Antibacterial And Antifungal Activities Of Sorindeia Madagascariensis And Albizia Harveyi Stem Barks, Paul Malaba Makoye, Sunday Mrutu, Innocent John Daniel, Mourice Nyangabo Mbunde, Joseph Sempombe, Veronica Mugoyela

Pharmaceutical Sciences and Research

The emerging multi-drug-resistant pathogens urge continuous searches for new antimicrobial agents. This study investigated the in vitro antibacterial and antifungal activities of the stem barks of two plants, Sorindeia madagascariensis and Albizia harveyi. Broth microdilution assay was used to determine the minimum inhibitory concentrations (MICs) of hydroethanolic extracts of the stem barks against selected bacteria and fungi. Both plant extracts exhibited activity against all tested microorganisms and their minimum inhibitory concentrations (MICs) against bacteria and fungi were from 1.67 to 5.00 mg/mL and from 1.67 to 10.00 mg/mL, respectively. This study reports the antibacterial and antifungal activities of the …

Freely Dissolved Organochlorine Pesticides (Ocps) And Polychlorinated Biphenyls (Pcbs) Along The Indus River Pakistan: Spatial Pattern And Risk Assessment, Muhammad Sohail, Syed Ali Musstjab Akber Shah Eqani, Habib Bokhari, Muhammad Zaffar Hashmi, Nadeem Ali, Ambreen Alamdar, Joel E. Podgorski, Dave Adelman, Rainer Lohmann

Graduate School of Oceanography Faculty Publications

Freely dissolved OCPs and PCBs were measured by using polyethylene passive samplers at 15 sites during 2014 throughout the stretch of the Indus River to investigate the spatial pattern and risk assess. Levels (pg/L) of dissolved ∑OCPs and ∑PCBs ranged from 34 to 1600 and from 3 to 230. Among the detected OCPs, dissolved DDTs (p,p′-DDE, followed by p,p′-DDT) predominated with levels of 0.48 to 220 pg/L. The order of occurrence for other studied OCPs was as follows: HCB, endosulfans, chlordanes, and HCHs. Spatially, dissolved (pg/L) ∑OCPs varied (p < 0.05) as the following: surface water of the alluvial riverine zone (ARZ) showed the highest levels (114) followed by the frozen mountain zone (FMZ) (52.9), low-lying zone (LLZ) (28.73), and wet mountain zone (WMZ) (14.43), respectively. However, our zone-wise PCB data did not exhibit significant differences (p > 0.05). Principal component analysis/multilinear regression results …

A Design Of Interactive Augmented Reality Mobile Learning Application For Ios-Based Device: Phytochemical Screening Material, Ruth Elenora Kristanty, Nashrul Hakiem

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Augmented Reality (AR) in the study of phytochemical screening is a technology that combines observation of experimental results in phytochemical screening as virtual objects with real environments. This study aimed to develop interactive learning media for phytochemical screening materials in the Phytochemistry Practicum at the Pharmaceutical and Food Analysis Department of Poltekkes Kemenkes Jakarta II. This interactive learning media application using AR technology was applied to iOS-based smartphones and designed for phytochemistry learning in the laboratory. The methods used in this study were descriptive exploratory for phytochemistry analysis and Multi- Media Development Life Cycled (MDLC) for AR development. 3D objects …

Estimating The Analytical Performance Of Raman Spectroscopy For Quantification Of Active Ingredients In Human Stratum Corneum, Hichem Kichou, Emilie Munnier, Yuri Dancik, Kamilia Kemel, Hugh Byrne, Ali Tfayli, Dominique Bertrand, Martin Soucé, Igor Chourpa, Franck Bonnier

Articles

Confocal Raman microscopy (CRM) has become a versatile technique that can be applied routinely to monitor skin penetration of active molecules. In the present study, CRM coupled to multivariate analysis (namely PLSR—partial least squares regression) is used for the quantitative measurement of an active ingredient (AI) applied to isolated (ex vivo) human stratum corneum (SC), using systematically varied doses of resorcinol, as model compound, and the performance is quantified according to key figures of merit defined by regulatory bodies (ICH, FDA, and EMA). A methodology is thus demonstrated to establish the limit of detection (LOD), precision, accuracy, sensitivity (SEN), and …

Increasing The Prevalence Of Risky Play In Preschool And Kindergarten Classrooms In The United States, Kelsey Stark Zuiderveen

Masters Projects

Risky play is a thrilling form of play that has the potential for some injury and is a biologically innate need within all children that provides a variety of physical, mental, and emotional benefits to children. Currently however, preschool and kindergarten classrooms in the United States offer little to no opportunities for risky play in early childhood settings. The main factor that influences the amount of risky play happening in early childhood classrooms is teacher attitudes related to risky play; if teachers have a negative attitude about risky play, less risky play is allowed in their classroom setting. This project …

The Regulation Of The Ownership Of Flats By Foreigners After The Enactment Of The Job Creation Law, Made Suksma Prijandhini Devi Salain, I Dewa Gede Palguna, I Gusti Ngurah Parikesit Widiatedja

Indonesia Law Review

The presence of foreigners in Indonesia for a long period certainly requires a place to live or a residential house. According to Article 144 (1) b of Job Creation Law, foreigners have the right to own flat units in Indonesia. Is this regulation intended to attract foreign investors? If it is yes, does not it contradictory to the “kenasionalan” principle stipulated in the Basic Agrarian Law (BAL) and other Indonesian regulations? This study is aimed to deal with those legal issues, by using the normative legal method. The result shows that the ownership right of flat units given to foreigners …

Yes Bank Annual Report 2021-22, Yes Bank Limited

Documents

No abstract provided.

Identifying The Protein That Mediates Sr1848'S Inhibition Of Lrh-1 Target Gene Expression, Allen Chan-Pong

Harriet L Wilkes Honors College Theses 2020 - Present

This project investigated the nuclear receptor LRH-1, which is primarily present in endodermal tissues. It affects several pathways such as lipid synthesis, glucose homeostasis, and embryonic development. However, LRH-1 is also often implicated in several cancers. In many types, tumorigenesis occurs due to LRH-1’s upregulation of the WNT/beta-catenin pathway, which promotes cell cycle progression. LRH-1 also promotes cancer proliferation by downregulating the cell cycle inhibitor p21. Targeting LRH-1 thus shows promise for treatment of the cancers it promotes. The small molecule SR1848 is an inhibitor of LRH-1 target gene expression, but it does not directly interact with LRH-1. This project …

Novel Context Exposure Enhances Object Recognition Memory: Assessing Involvement Of Norepinephrine Neurotransmission, Eleonora Lurie

Harriet L Wilkes Honors College Theses 2020 - Present

Long-term memories are encoded within the hippocampus, but some are quickly forgotten. Brief exposure of mice to a novel context following encoding of object memory significantly enhances consolidation of the object memory. The memory-enhancing effect of post-training novelty may rely on locus coeruleus tyrosine-hydroxylase expressing neurons which co-release norepinephrine and dopamine in the hippocampus. To test the contribution of norepinephrine to this novelty effect, mice received propranolol, a synthetic beta-adrenergic receptor antagonist (10 mg/kg), to block norepinephrine or 0.9% saline as a control post-training. Pre-novel context exposure and object memory was tested 24 hr later. Results revealed that propranolol did …

Pediatric And Child Health Nursing: A Three-Phase Research Priority Setting Study In Western Australia, Evalotte Mörelius, Ailsa Munns, Stephanie Smith, Helen J. Nelson, Anne Mckenzie, Jade Ferullo, Fenella J. Gill

Research outputs 2022 to 2026

Purpose: Priority settings are important to plan and direct future research. The aim of this study was to identify the top ten pediatric and child health nursing research priorities from the perspectives of consumers, community, and healthcare professionals in Western Australia.

Design and methods: This study used an adapted James Lind Alliance Priority Setting Partnership design with three phases. 1) A planning workshop to inform a survey. 2) A survey using five open-ended-questions distributed between October 2020 and January 2021 through social media and healthcare professionals' emails. Responders' statements were analyzed with content analysis. 3) A consensus workshop to finalize …

Effects Of Social And Personal Norms, And Connectedness To Nature, On Pro-Environmental Behavior: A Study Of Western Australian Protected Area Visitors, Joanna Pearce, Songshan (Sam) Huang, Ross K. Dowling, Amanda J. Smith

Research outputs 2022 to 2026

Pro-environmental behaviors play a key role in the management and sustainability of parks and protected areas. An understanding of the antecedents of visitors' pro-environmental behaviors is vitally important in advancing knowledge, encouraging sustainability, and bettering management practice. This study developed and tested a behavioral model which integrated personal norms and social norms as normative influences, with connectedness to nature as a personality trait, as antecedents of pro-environmental behaviors. Data were collected through a visitor survey across three protected areas in Western Australia and analyzed via structural equation modelling. Results indicated that personal norms and connectedness to nature had a positive …

Procurement Decisions On The Transportation Of Food Aid In Humanitarian Operations, A-R Kim, To Schneider, S-Y Roh, Y-J Seo

Plymouth Business School

Purpose The purpose of this research is to see how purchasing decisions affect food aid transit in humanitarian operations. In this context, the four criteria of transportation time, transportation costs, transportation capacity, and food loss and waste are assessed in relation to local and global procurement procedures, as well as the usage of pre-positioned stock. As a result, this research establishes the correlations between the criteria and gives implications for improvement. Design/Methodology/Approach Within the mono-method quantitative study, a single data collection method is used. We gathered data from respondents working in food aid using a survey, namely an online questionnaire. …

Sepsis And Acute Kidney Failure Outcomes Investigated In A Rural, Midwestern Population, Jenessa B. Lemon, Quinn Bohn, Shelly N.B. Sloan, Greg Stahl, Kerry Johnson, Scott Goade, Robert Arnce

Faculty and Staff Publications

Background:

The American healthcare system spends a large amount of economic and human resources on fighting acute sepsis. Even with years of research, mortality rates remain high. Reducing mortality outcomes from sepsis by elucidating biomarkers and the role secondary comorbidities play could assist in sepsis triage and improve outcomes in septic patients. The purpose of this study is to assess to what degree one secondary comorbidity, acute kidney failure, contributes to mortality rates among acutely septic patients in a rural Midwestern hospital located in southwest Missouri.

Methods:

Cohort study assessing septic patients with and without acute kidney injuries (AKIs). ICD10 …

Mri-Based Synthetic Ct Images For Impt Treatment Planning Of Nasopharyngeal Carcinoma Patients, Shupeng Chen, Y Peng, Y Liu, C Zhao, X Deng, An Qin, Di Yan, Craig Stevens, Rohan Deraniyagala, Xuanfeng Ding

Conference Presentation Abstracts

Purpose or Objective To investigate the feasibility of using an MRI-based synthetic CT image (SCT) generated via a generative adversarial network (GAN) for intensity-modulated proton therapy (IMPT) treatment planning of nasopharyngeal carcinoma (NPC) patients. Materials and Methods T1-weighted MR images and paired CT (PCT) images were obtained from 158 NPC patients with radiotherapy immobilization. Deformable image registration was performed between each MR and PCT image for each patient to create an MR-CT pair. Thirteen pairs were randomly chosen as independent test sets and the remaining 145 pairs (10 for validation and 135 for training) were used to build a conditional …

Parents' Experiences Of Children With A Rare Disease Attending A Mainstream School: Australia, Mandie Foster, Esther Adama, Diana Arabiat, Kevin Runions, Rena Vithiatharan, Maggie Zgambo, Ashleigh Lin

Research outputs 2022 to 2026

Purpose:

To explore the perceptions of parents who had a child or adolescent (6-18 years) diagnosed with a rare disease who attended a mainstream school in Western Australia.

Design and methods:

A cross-sectional online survey was conducted with 41 parents of children with a rare disease. Here we report the findings of 14 open-ended questions on their experience of illness-related factors and impact on school-related social activities, such as sports, school camps and leadership roles whilst their child with a rare disease attended a mainstream school in Australia. Responses were analysed using an inductive thematic content approach.

Results:

We identified …

Nutrigenetic Reprogramming Of Oxidative Stress, Joseph Ryu, Huzeifa Gulamhusein, Jin Kyun Oh, Joseph H. Chang, Jocelyn Chen, Stephen H. Tsang

School of Medicine Publications

Retinal disorders such as retinitis pigmentosa, age-related retinal degeneration, oxygen-induced retinopathy, and ischemia-reperfusion injury cause debilitating and irreversible vision loss. While the exact mechanisms underlying these conditions remain unclear, there has been a growing body of evidence demonstrating the pathological contributions of oxidative stress across different cell types within the eye. Nuclear factor erythroid-2-related factor (Nrf2), a transcriptional activator of antioxidative genes, and its regulator Kelch-like ECH-associated protein 1 (Keap1) have emerged as promising therapeutic targets. The purpose of this review is to understand the protective role of the Nrf2-Keap1 pathway in different retinal tissues and shed light on the …

Red Harvester Ant (Pogonomyrmex Barbatus F. Smith; Hymenoptera: Formicidae) Preference For Cover Crop Seeds In South Texas, Lilly Victoria Elliott-Vidaurri, Daniella Rivera, Adrian Noval, Robin A. Choudhury, Hannah J. Penn

School of Earth, Environmental, & Marine Sciences Faculty Publications

Harvester ants often selectively forage seeds, causing these ants to be viewed as pests in agricultural areas where they may forage on crop seeds. While little research has been done on harvester ant preferences for cover crop seeds, grower observations in the Lower Rio Grande Valley (LRGV) suggest that ants may remove these seeds before germination. We examined red harvester ant (Pogonomyrmex barbatus F. Smith) preferences for cover crop seeds (fescue, oat, sunn hemp, radish, vetch, and wheatgrass) and the effects of a commonly used bacterial seed inoculant. We evaluated relative preferences using seed depots presented to colonies with no …

Mitragyna Speciosa As A Potential Substitute Therapy In Opioid Dependence: A Case Report, Karniza Khalid, Jason S.K. Wong, Ruzita Jamaluddin

Pharmaceutical Sciences and Research

Preclinical data have consistently suggested the pharmaceutical potential of kratom (Mitragyna speciosa), including as a substitute therapy in opioid dependence. In this case report, we present a case of a man with a long history of kratom use to help him cope with his opiate withdrawals while abstaining from illicit drug use. This is the first published detailed case report highlighting the potential use of kratom to aid opioid dependence encountered in the clinical setting. Our article is also supported by literature review with regards to kratom’s safety profile and pharmacological potential.

Crispr/Cas9 Genome Editing: Future Treatment Of Duane Retraction Syndrome, Muhammad Raihan Zulfikar, Editha Renesteen, Bantari W.K. Wardhani

Pharmaceutical Sciences and Research

Duane Retraction Syndrome (DRS) is characterized by limited eye movement. One of its causes is a mutation in the CHN1, MAFB, or SALL4 gene. Nowadays, the treatment for DRS is limited to glasses, occlusion, and surgery. However, this treatment has not been able to cure the disease’s hereditary issue. Another strategy to be considered for the treatment is CRISPR/Cas9, a tool for performing gene editing with a wide range of applications, including treating genetic diseases. We made sgRNA as a first step in using CRISPR/Cas9 as a treatment for DRS in silico using the CCTop website. By computing sgRNA, conducting …

Identification Of Community Knowledge On Lead Contamination And Analysis Of Lead Level In Fish, Sita Nurwulan, Sophi Damayanti, Lia Amalia

Pharmaceutical Sciences and Research

Poisoning is an event of human exposure to poisonous substances that are harmful to the body at certain doses. Lead is a heavy metal that can cause toxicity, including neurotoxic effects, hypertension, digestive system disorders, bone and tooth growth disorders, immune system disorders, infertility, and fetal disorders. Fish is a source of nutrients that are often consumed by people, however can also accumulate lead. This study aimed to analyze the lead level in fish and identify the community knowledge level regarding lead contamination in fish. Identification of community knowledge levels regarding lead. Identification of community knowledge levels regarding lead contamination …

Signal-To-Noise Analysis Can Inform The Likelihood That Incidentally Identified Variants In Sarcomeric Genes Are Associated With Pediatric Cardiomyopathy, Leonie M Kurzlechner, Edward G Jones, Amy M Berkman, Hanna J Tadros, Jill A Rosenfeld, Yaping Yang, Hari Tunuguntla, Hugh D Allen, Jeffrey J Kim, Andrew P Landstrom

Faculty, Staff and Students Publications

Background: Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiomyopathy and can predispose individuals to sudden death. Most pediatric HCM patients host a known pathogenic variant in a sarcomeric gene. With the increase in exome sequencing (ES) in clinical settings, incidental variants in HCM-associated genes are being identified more frequently. Diagnostic interpretation of incidental variants is crucial to enhance clinical patient management. We sought to use amino acid-level signal-to-noise (S:N) analysis to establish pathogenic hotspots in sarcomeric HCM-associated genes as well as to refine the 2015 American College of Medical Genetics (ACMG) criteria to predict incidental variant pathogenicity.

Methods and …

Strategic Management Accounting Information And Performance: Mediating Effect Of Knowledge Management, Ruhanita Maelah, Baha'a Aldeen Hussein Mohamed, Amizawati Mohd Amir

The South East Asian Journal of Management

Research Aims: The objective of this study is to examine the relationship ‎between Strategic Management Accounting (SMA) information, Knowledge Management (KM), and the performance of ‎Malaysian hospitals.

Design/methodology/approach: A survey is employed, and data is collected using self- administered questionnaires. Responses from 95 Malaysian private hospitals were ‎analysed using Partial Least Squares (PLS) 3.0.

Research Findings: The findings indicate that SMA ‎information positively affects ‎performance, and KM mediates the ‎relationship between SMA information and interpretation.

Theoretical Contribution/Originality: This study utilised the Resource-Based View (RBV) theory to explain SMA information as a resource and KM as a capability that impacts the …

Job Satisfaction And Turnover Intention Among Malaysian Private University Academics: Perceived Organisational Support As A Moderator, Septriyan Orpina, Nurul Iman Binti Abdul Jalil, T'Ng Soo Ting

The South East Asian Journal of Management

Research Aims: The present research examines the extent to which job satisfaction predicts turnover intentions and examines the extent to which perceived organisational support moderates the association between job satisfaction and turnover intention among academics in Malaysian private universities.

Design/Methodology/Approach: This research adopted a quantitative method. The Turnover Intention Scale (TIS-6), Minnesota Satisfaction Questionnaire (MSQ), and Survey of Perceived Organisational Support (SPOS) questionnaires were administered. Multistage cluster random sampling was used in this study. A total of 327 respondents provided valid data and analysed it using SPSS Process Macro Version 3.5.

Research Findings: Job satisfaction was found to be a …

Motivating First-Generation Factory Employees: A Case Study Of The Garment Industry In Myanmar, Eitaro Kojima, Akihiko Ohno

The South East Asian Journal of Management

Research Aims: This study investigates how to foster and motivate factory employees at the onset of industrialisation.

Design/methodology/approach: A total of 728 employees of the garment sector in Myanmar were surveyed using a structured questionnaire.

Research Findings: The results of this study indicate 1) that employees’ maladaptation to factory discipline leads to workplace stress and fuels employees’ counter-productive behaviour and 2) that employees who perceive benevolence from the factory manager take on pro-organizational (vs counter-productive) behaviour based on social exchange rooted in indigenous patron-client ties.

Theoretical Contribution/Originality: This study discusses the singular aspects of human resource …

Work-Family Enrichment: Does It Help Manage Emotional Exhaustion During The Covid-19 Pandemic?, Syayyidah Maftuhatul Jannah, Anniza Citra Prajasari, Noni Setyorini

The South East Asian Journal of Management

Research Aims: This study aims to analyse the role of work-family enrichment on emotional labour and the impact of emotional exhaustion during the COVID-19 pandemic.

Design/methodology/approach: The type of data collected is primary data that uses an online questionnaire. The sampling method is a purposive sampling technique. The PLS-SEAM is used to analyse the collected data.

Research Findings: Work-family enrichment and family-work enrichment had a positive and significant effect on emotional labour (surface acting and deep acting) and on emotional exhaustion.

Theoretical Contribution/Originality: The results of this study show the importance of the role of work …

Indonesia Female Principal Performance Appraisal: Gender Perspective, Rahma Widyawati, Anik Sri Widowati, Mei Maemunah, Istiningsih Istiningsih, Eny Nurnilawati, Widyanti Kurnianingsih

The South East Asian Journal of Management

Research Aims: This study aimed to determine the direct influence of communication style and individual competence on female principals' empowering leadership and performance in Yogyakarta, Indonesia.

Design/methodology/approach: The respondents of this study were 220 teachers from 3 accredited high schools with female principals in Yogyakarta, Indonesia. The questionnaire was analysed using structural equation modelling with AMOS to determine the relationship between variables and using Sobel Test to test leadership as a mediating variable.

Research findings: The results of this study show that communication style and competence have a positive and significant effect on leadership and performance, leadership has a significant …

Library Environmental Factors And Students’ Patronage Of Library Services In The University Of Uyo Main Library, Clement Udo, Edidiong Nyong Ben Mr

Library Philosophy and Practice (e-journal)

This study examined the influence of library environmental factors on students’ patronage of library services in the university of Uyo main library. The factors under investigation are library aesthetics, library lighting, library ventilation, library spacing and students’ patronage of library services. Four specific purposes were coined using the factors. Four research questions and hypotheses coined from the specific purposes were stated to guide the study. The descriptive survey design was used for the study. The study was conducted in Akwa Ibom State using the University of Uyo main library as a case study. The population was 150 respondents, comprising level …

Use Of Mobile Learning Applications And Academic Engagement Of Library And Information Science Students In Universities In South-West, Nigeria, Julie Owansuan Olalere, Opeyemi Deborah Soyemi Phd

Library Philosophy and Practice (e-journal)

ABSTRACT

The study investigated the influence of use of mobile learning applications on academic engagement of Library and Information Science students in universities in South-West, Nigeria. The study adopted survey research design and questionnaire was used for data collection. One hundred and ninety-nine (199) copies of the questionnaire were administered out of which 184 copies were retrieved and fit for data analysis resulting in a 93% response rate. Analysis was done using SPSS version 23, percentages, mean, and standard deviation were used to analyse research questions and regression for the hypothesis which was tested at 0.05 level of significance. The …