Digital Commons Network^™

America’S Cash Bail Crisis: Learning From Our Common-Law Roots, Jake Feiler

Loyola of Los Angeles International and Comparative Law Review

No abstract provided.

Young‐Onset Colorectal Cancer: Insights From An English Population‐Based Study, Joshua Franklyn, Joe Lomax, Peter L.Z. Labib, Amy Baker, Supriya Balasubramanya, Joe Natale, Muhammad Abdalkoddus, Joanne Hosking, Mark G. Coleman, Sebastian Smolarek

Peninsula Medical School

No abstract provided.

Blue Zones: Unlocking Key Themes In The Centenarian's Life, Grace Beer, Grace O. Beer

Honors College Theses

Longevity has been sought after in certain areas of the world, and there are specific regions where this has been achieved. There is an American average life expectancy of 72 years old, but individuals in “Blue Zones” here in America and other areas of the world are expected to and have proven to live well beyond 100. The areas of Okinawa, Sardinia, Nicoya, Ikaria, and Loma Linda are classified as Blue Zones, and there could be more of an understanding of how these people live the way they do to have such healthy physical outcomes. To deeply understand the strategy …

Spectrum, Senior Edition 2022, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: The Heroes of SCMA by Tomas Koeck and Maisy Carvalho -- Editorials: Maisy Carvalho, Ashlin Haley, Julia Hallisey, Theo Haubrich, Jenn Hallowell, Sophie Camizzi, Emilee Camodeo, Jacqueline Champoux, Elizabeth Coyne, Deanna Reinhardt, Amber Martinez -- A Message from Professor Kabak

2022 Residential Metals Abatement Program (Rmap) Field Sampling Plan (Fsp) – Indoor Dust – Group 2 West Elementary, Elsie King, Christopher Berg, Thomas J. Beckman

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Lindenwood Digest, May 4, 2022, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

China, Europe, And The Pandemic Recession: Beijing’S Investments And Transatlantic Security, John R. Deni, Chris Alden, Erik Brattberg, Roger Cliff, Mark Duckenfield, R. Evan Ellis, Nicholas Nelson, Lauren Speranza

Books, Monographs & Collaborative Studies

Given the depth and breadth of the pandemic-induced recession in Europe, private companies in need of capital and governments looking to shed state-owned enterprises may be tempted to sell shares, assets, or outright ownership to investors with liquidity to spare. Of greatest concern is the role that China might play in Europe, building Beijing’s soft power, weakening allied geopolitical solidarity, and potentially reprising the role it played in the 2010s, when its investments in Europe expanded dramatically. More specifically, there is concern over China’s investments in infrastructure and sensitive technologies relevant to American and allied military operations and capabilities.

Whether …

Student Perceptions Of Gendered Racial Microagressions, Ayanna Brewton

Honors College Theses

The impact of stereotypes, prejudice, and discrimination is a widespread issue in society that has become more visible to people with privilege and has been more widely studied by social scientists and mental health professionals. More recently, the impact of gendered racial microaggressions has been investigated. Gendered racial microaggressions are defined as indirect and everyday slights and insults based on the intersection of racism and sexism (Gadson & Lewis, 2021). Research shows that gendered racial microaggressions toward multiple minority status individuals has a negative impact on their mental wellbeing (Mekawi & Todd, 2018). However, there is a gap in the …

Effects Of Water Quality On Oyster Health On Georgia Coast, Laurel Henderson

Honors College Theses

ABSTRACT

Oysters are an economically and ecologically important shellfish species found along most coastlines. Along the Georgia coastline, oysters form extensive reefs, and are economically important as a food source. In addition, oysters perform a vital role in maintaining water quality due to their high filtration capacity in coastal waters. Oyster reefs form solid, 3-D substrate that prevent coastline erosion and provide structure for numerous other coastal species to grow, including many commercially and recreationally important species. Water quality factors, such as temperature and salinity, can influence oyster density, condition, and growth, and ultimately affect the services the reefs provide …

Office Of Research, Economic Engagement And Outreach Update, May 4, 2022, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Silver Bow Creek/Butte Area Npl Site Butte Priority Soils Operable Unit, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Factors Determining Attraction Of Neurodivergent Applicants To Organizations, Barri Levitt

Senior Honors Papers / Undergraduate Theses

Neurodivergence is used to describe a broad range of neurodevelopmental differences that result in a distinct set of challenges for individuals in interacting with the world around them. Within Diversity, Equity and Inclusion campaigns, neurodiversity is the term used to describe the composition of a space to include neurodivergent and neurotypical individuals. The unique perspectives that come from workplace neurodiversity are a valuable tool, yet companies are routinely missing out on the addition of neurodivergent individuals because of current hiring practices. This study was developed using the theoretical bases of person-organization fit, which emphasizes value congruence between organizations and employees, …

A Bayesian Group Sequential Design For Randomized Biosimilar Clinical Trials With Adaptive Information Borrowing From Historical Data, Wen Zhang, Zhiying Pan, Ying Yuan

Faculty, Staff and Student Publications

At the time of developing a biosimilar, the reference product has been on market for years and thus ample data are available on its efficacy and characteristics. We develop a Bayesian adaptive design for randomized biosimilar clinical trials to leverage the rich historical data on the reference product. This design takes a group sequential approach. At each interim, we employ the elastic meta-analytic-predictive (EMAP) prior methodology to adaptively borrow information from the historical data of the reference product to make go/no-go decision based on Bayesian posterior probabilities. In addition, the randomization ratio between the test and reference arms is adaptively …

Privacy Assessment Breakthrough: A Design Science Approach To Creating A Unified Methodology, Lisa Mckee

Masters Theses & Doctoral Dissertations

Recent changes have increased the need for and awareness of privacy assessments. Organizations focus primarily on Privacy Impact Assessments (PIA) and Data Protection Impact Assessments (DPIA) but rarely take a comprehensive approach to assessments or integrate the results into a privacy risk program. There are numerous industry standards and regulations for privacy assessments, but the industry lacks a simple unified methodology with steps to perform privacy assessments. The objectives of this research project are to create a new privacy assessment methodology model using the design science methodology, update industry standards and present training for conducting privacy assessments that can be …

Sb109-21/22-Resolution Urging The University Of Montana To Institute A Naloxone Policy, Emma Kiefer

Senate Resolutions, 2007-Present

SB109-21/22-Resolution Urging the University of Montana to Institute a Naloxone Policy. This resolution passed unanimously during the May 4, 2022 meeting of the Associated Students of the University of Montana (ASUM).

Anhedonia Reduction Correlates With Increased Ventral Caudate Connectivity With Superior Frontal Gyrus In Depression., Xinhua Yang, Jia Huang, Matthew E. Roser, X Guangrong

School of Psychology

This study was to investigate the relationship between the ventral caudate connectivity and anhedonia. Nineteen depressed patients and 16 healthy controls participated in two identical functional magnetic resonance imaging scans during a 1-year period to determine the resting-state functional connectivity changes using a seed-based approach. Patients showed increased left ventral caudate functional connectivity with superior frontal gyrus over time and the increased connectivity was associated with anhedonia improvement. None of these associations were observed in healthy controls. The findings suggest that left ventral caudate may serve as a potential target to improve the severity of anhedonia.

How Program Directors Understand General Surgery Resident Wellness, Darci C. Foote, Julie Evans, Tedi Engler, Alisha Lussiez

Conference Presentation Abstracts

No abstract provided.

What Are Student And Staff Perspectives On The Influence Of Smaller Learning Communities On Sense Of Belonging And Academic Achievement?, Natalie A. Saiz

Teacher Education, Educational Leadership & Policy ETDs

ABSTRACT

In an era of educational reform, schools face the significant challenge of increasing academic achievement. Learning Communities have emerged as a method of school reform with some research suggesting their link to increasing academic achievement and personalizing learning environments. Using individual and focus group interviews, this qualitative case study examines the use of Learning Communities as a reform initiative at a high school in New Mexico to facilitate a stronger sense of belonging among students and to provide individualized guidance, tracking, and support. Findings on the influence of Learning Communities are presented: addition of Advisory/Advisor which provides academic assistance, …

Legal Aspects Of Student Social Media Behavior In Health Sciences Education, Julie H. Schiavo

Library Faculty Publications

No abstract provided.

Elucidating Human Milk Oligosaccharide Biosynthetic Genes Through Network-Based Multi-Omics Integration, Benjamin P Kellman, Anne Richelle, Jeong-Yeh Yang, Digantkumar Chapla, Austin W T Chiang, Julia A Najera, Chenguang Liang, Annalee Fürst, Bokan Bao, Natalia Koga, Mahmoud A Mohammad, Anders Bech Bruntse, Morey W Haymond, Kelley W Moremen, Lars Bode, Nathan E Lewis

Children’s Nutrition Research Center Staff Publications

Human Milk Oligosaccharides (HMOs) are abundant carbohydrates fundamental to infant health and development. Although these oligosaccharides were discovered more than half a century ago, their biosynthesis in the mammary gland remains largely uncharacterized. Here, we use a systems biology framework that integrates glycan and RNA expression data to construct an HMO biosynthetic network and predict glycosyltransferases involved. To accomplish this, we construct models describing the most likely pathways for the synthesis of the oligosaccharides accounting for >95% of the HMO content in human milk. Through our models, we propose candidate genes for elongation, branching, fucosylation, and sialylation of HMOs. Our …

“What Is The Matter With Me?” Or A “Badge Of Honor”: Nurses’ Constructions Of Resilience During Covid-19, Anna Conolly, Ruth Abrams, Emma Rowland, Ruth Harris, Keith Couper, Daniel Kelly, Bridie Kent, Jill Maben

School of Nursing and Midwifery

It has long been known that nursing work is challenging and has the potential for negative impacts. During the COVID-19 pandemic most nurses’ working landscapes altered dramatically and many faced unprecedented challenges. Resilience is a contested term that has been used with increasing prevalence in healthcare with health professionals encouraging a “tool-box” of stress management techniques and resilience-building skills. Drawing on narrative interview data ( n = 27) from the Impact of Covid on Nurses (ICON) qualitative study we examine how nurses conceptualized resilience during COVID-19 and the impacts this had on their mental wellbeing. We argue here that it …

Humanising Health And Social Care Support For People With Intellectual And Developmental Disabilities: Protocol For A Scoping Review, Madison Milne-Ives, Rohit Shankar, Dan Goodley, Kirsten Lamb, Richard Laugharne, Tracey Harding, Edward Meinert

Peninsula Medical School

Background Health care is shifting toward a more person-centered model; however, people with intellectual and developmental disabilities can still experience difficulties in accessing equitable health care. Given these difficulties, it is important to consider how humanizing principles, such as empathy and respect, can be best incorporated into health and social care practices for people with intellectual and developmental disabilities to ensure that they are receiving equitable treatment and support. Objective The purpose of our scoping review is to provide an overview of the current research landscape and knowledge gaps regarding the development and implementation of interventions based on humanizing principles …

Und Strategic Planning Focus Group Notes: Student Veteran Organization, University Of North Dakota

LEADS Development Documents

Notes from a May 4, 2022 UND strategic planning focus group with members of the Student Veteran Organization. The notes capture student veteran perspectives on choosing UND, military-friendly programs and services, aviation and online education, campus professionalism, student organizations, community, affordability, and future opportunities for UND.

Study Of Soil Lead Levels In Gwinnett County, Jaci Carithers, Alexis Katz, Philipa Wang, Farmaan Judge, Brian Matayoshi

Research Day

INTRODUCTION: The CDC estimates that over half a million US children between ages 1-5 have blood lead levels high enough to damage their health. No level of lead can exist safely in the human body, especially since lead does not aid any of its biological processes and, actually, impedes these processes. Past use of lead paint, leaded gasoline, and manufacturing and disposal procedures in lead-based industries have contributed to lead contamination of soil and water. Now, the risks of lead contaminated soil and produce in urban community gardens pose a new challenge. Saikawa Labs at Emory discovered lead slag in …

Assessing The Safety And Efficacy Of Finerenone In Patients With Chronic Kidney Disease (Ckd) And Comorbid Type Ii Diabetes (T2d), A Systematic Review, Barry Brown

Research Day

Introduction: Potassium-sparing diuretics have long since held an important place in clinical practice; though, there are only a handful of options available. A novel potassium sparing diuretic, finerenone, has recently been investigated in patients with CKD with concomitant T2D to determine its safety and efficacy in a larger group of patients.

Objectives: The purpose of this abstract is to identify and analyze phase III trial data of novel diuretic therapies in patients with CKD and comorbid T2D.

Methods: The terms, “chronic kidney disease”, “type 2 diabetes”, “new therapy”, “effect”, “renal function”, and “cardiovascular disease”, were utilized to conduct a systematic …

A Novel Method For Studying Cerebellar Responses To Tdcs Using Mice: An In Vitro Approach, Madison Cohen, Eashwar Mohan, Sagar Darira, Emily Graves, Huo Lu

Research Day

Cerebellar ataxias are a group of neurodegenerative disorders associated with impaired cerebellar circuitry leading to loss of motor coordination and balance. Recent studies using animal models have shown that transcranial direct stimulation (tDCS) could be an effective therapy for the treatment of cerebellar ataxia. The sole output of the cerebellar cortex is from the axons of Purkinje cells, which allows the cerebellum to influence motor behavior via the cerebello-thalamo-cortical pathway. However, the influence of tDCS on Purkinje cells remains unknown. In this study, we used a customized whole-cell patch-clamp chamber, which allowed for patch-clamp recordings from Purkinje cells during tDCS. …

Pcom Partners: Empowering Community Members To Reduce Covid-19 Vaccine Hesitancy, Jeisson Garcia, Gloria Joseph, Darwin Mendez, Sheeren Mohammed, Danielle Myara, Jessica Myara, Jaclyn Zibman, Megha Bhagavan, Allison Smith, Mallory Hidinger, Brian Matayoshi

Research Day

As of March 24th, 2022, more than 400 million individuals have contracted the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide with a death toll count of over six million victims. SARS-CoV-2 is an anti-discriminatory virus that affects humanity as a whole. As society navigates through this pandemic, science has found a way to improve the human body’s ability to fight against the virus by creating a vaccine against the virus. Currently there are vaccines with a high rate of effectiveness against the different variants of the virus. However, vaccine hesitancy is a major obstacle in the fight against the …

Barbaloin (Aloin-A) And Isobarbaloin (Aloin-B) Selectively Inhibit Activity Of Papain Like Protease (Plpro) Of Sars-Cov-2 In Vitro, Devin Shane Lewis, Krishna Chavada, Joanna Ho, Savannah Wills, Srujana Rayalam, Vicky Mody, Shashidharamurthy Taval

Research Day

In human adapted corona viruses (including SARS-CoV-2), the most common host entry point is through the initial colonization in the laryngeal and pharyngeal regions which are responsible for spread of the infection. Recent studies suggest that commercially available oral and nasal rinse products are effective in inhibiting the viral replication, however, the anti-viral mechanism of the active ingredients present in the oral rinses have yet to be studied. In the present study, we have assessed in vitro enzymatic inhibitory activity of active ingredients in the oral mouth rinse products: aloin-A and B, chlorhexidine, eucalyptol, hexetidine, menthol, triclosan, methyl salicylate, sodium …

Isolation And Recording Of Thalamic Neuronal Activity From Ventral Medial And Ventral Lateral Thalamic Nuclei In Rat, Michael Bien, Halley Fowler, Jessica Hiscox, Anum Ul-Haque, Huo Lu

Research Day

The cerebellum, known for its role in coordination and motor adaptation, is hypothesized to travel through the thalamus in its signaling to and from the cerebral cortex, specifically through the ventral medial (VM) and ventral lateral (VL) thalamic nuclei. The thalamus is located within the diencephalon between the midbrain and cerebral cortex. It is an important relay center between the cerebellum and the motor cortex.

Isolation and recording of electrical activity from neurons in the ventral medial and ventral lateral thalamic nuclei in rats is the first step to study the thalamic response to electrical cerebellar stimulation in future experiments. …

Robotic Versus Laparoscopic Cholecystectomy: A Meta-Analysis, Lana Aleuy, Oluwaferanmi Akande, Aliu Sanni

Research Day

Background: Laparoscopic cholecystectomy (LC) remains the gold standard management of benign gallbladder disease. The adoption of the robotic platform that offers high-resolution 3- dimensional images, dexterity, better range of motion, and precise control in comparison to laparoscopic cholecystectomy (LC) into general practice is still lacking. Recent data on the safety and efficacy of Robotic cholecystectomy (RC) in comparison to LC has not yet been analyzed. The aim of this study is to evaluate the effectiveness and safety of RC compared to LC for gallbladder disease from articles published after 2017.

Methods: A systematic review was conducted using EMBASE, PubMed, and …