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When Stress Matters Most: Developmental Timing And Socio-Ecological Stressors Among Mexican-Origin Adolescents From Low-Income Immigrant Families, Ka I Ip, Wen Wen, Sujin Lee, Wei Xiang Sim, Su Yeong Kim

Research Collection School of Social Sciences

This study investigates the dynamic, time-varying associations between multiple socio-ecological stressors and internalizing symptoms among Mexican-origin youth from low-income immigrant families. Grounded in a socioecological framework and employing time-varying effect modeling (TVEM), we examine how stressors at the interpersonal, family, and neighborhood levels differentially influence anxiety and depressive symptoms across early adolescence (ages 11–13), middle adolescence (ages 14–17), and late adolescence/emerging adulthood (ages 18–20). Participants included 604 Mexican-origin adolescents (54% female) from low-income immigrant families, assessed across three waves spanning nine years. Five distinct stressors were identified: discrimination, foreigner stress, economic stress, language brokering stress, and neighborhood violence/non-safety. Results from …

Interpretable Machine Learning For Personalized Profiling Of Mild Cognitive Impairment From Daily Activities, Budhitama Subagdja, Ah-Hwee Tan, Kenneth Kwok, Iris Rawtaer

Research Collection School Of Computing and Information Systems

Continuous monitoring of individual daily activities is essential to detect mild cognitive impairment (MCI) wherein timely intervention can still be applied to prevent more severe mental decline. Recent approaches in predicting MCI are mostly considering digital biomarkers across individuals but often neglecting specific indicators from a single person over a long period of time. Making this personalized, dynamic, and highly noisy prediction model with irregular distribution of missing information to be explainable and actionable for clinical use, remains a challenge. This paper presents a study on a personalized MCI prediction and profiling from an in-home and mobile cognitive health monitoring …

Navigation Beyond Wayfinding: Robots Collaborating With Visually Impaired Users For Environmental Interactions, Shaojun Cai, Nuwan Janaka, Ashwin Ram, Janidu Shehan, Yingjia Wan, Kotaro Hara, David Hsu

Research Collection School Of Computing and Information Systems

Robotic guidance systems have shown promise in supporting blind and visually impaired (BVI) individuals with wayfinding and obstacle avoidance. However, most existing systems assume a clear path and do not support a critical aspect of navigation—environmental interactions that require manipulating objects to enable movement. These interactions are challenging for a human–robot pair because they demand (i) precise localization and manipulation of interaction targets (e.g., pressing elevator buttons) and (ii) dynamic coordination between the user’s and robot’s movements (e.g., pulling out a chair to sit). We present a collaborative human–robot approach that combines our robotic guide dog’s precise sensing and localization …

The Health Of Latinos In Massachusetts: Inequality In Health Behaviors And Chronic Health Conditions, Phillip Granberry, Alejandro Alvarez, Florita Coto Tristán

Gastón Institute Publications

This report provides a portrait of adult Latino health in Massachusetts by exploring and describing selected social indicators and health outcomes. This report is a companion to a 2021 report on Latino children in the state, which found that Latino children are more likely to have asthma, be overweight, and show symptoms of anxiety and depression, and less likely to be engaged in physical activity when compared to Non-Latino children. The foregoing findings suggested that Latino children are not developing in an environment that promotes health behaviors compared to Non-Latinos in Massachusetts.v The collective health of Latinos is said group …

Latinos In Massachusetts: Puerto Ricans, Phillip Granberry, Florita Coto Tristán, Melissa Colón

Gastón Institute Publications

As part of the Gastón Institute’s 2025 Latinos in Massachusetts series, we present here a profile of Puerto Ricans, the largest Latino population in the state. This report analyzes Public Use Microdata Sample (PUMS) data from the 2023 American Community Survey (ACS), conducted by the U.S. Census Bureau. Our descriptive analysis uses both household- and individual-level data to estimate population size and percentages and to compare Puerto Ricans to Other Latinos and Non-Latinos in the state.

March 2026 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Hospital-Presenting Self-Harm And Suicide Among Justice-Involved Adolescents On Community-Based Orders: A Population-Based Cohort Study, Emaediong I. Akpanekpo, George Karystianis, Jocelyn Jones, Tony Butler

Research outputs 2022 to 2026

Objective To estimate the incidence and identify risk factors for hospital-presenting self-harm and suicide among justice-involved adolescents serving community-based orders in New South Wales, Australia. Method We conducted a population-based retrospective cohort study of 44,887 adolescents aged 10–17 years at first proven offence who received community-based orders between 1994 and 2020. Hospital and emergency department records were linked with mortality, child protection, and justice data. Cox regression estimated hazard ratios (HRs) for self-harm, and Fine-Gray models estimated subdistribution HRs for suicide, accounting for competing risks. Results Over 163,676 person-years, 1901 adolescents had a first self-harm episode (11.6 per 1000 person-years), …

Participatory Action Research (Par) In Designing A Supplementary Animated Teaching Resource To Support Learning Cervical Assessment, Michelle Gray, Shelley Stuart, Melanie Welfare

Research outputs 2022 to 2026

Aim: To create an education resource that assists students to understand the movement of the cervix during labour from a posterior retroverted position to a central location, cervical effacement, dilatation of the cervix and descent of the fetal skull. Background: Learning about anatomy and physiology in relation to cervical effacement and dilatation are abstract concepts that are difficult to understand from reading alone. Diagrams are of little assistance however 3D animation has the potential to improve students learning experiences. Design: Participatory Action Research (PAR) using the 7 C's Feekery Framework approach was adopted. Participants became coresearchers in conceptualising the learning …

Physical Fitness And Executive Functions In Early Childhood: A Systematic Review Of Recent Evidence, Nemanja Lakicevic, Marko Manojlovic, Elena Chichinina, Apollinaria Chursina, Kristina Tarasova, Ewan Thomas, Yuming Zhong, Antonino Bianco, Patrik Drid

Research outputs 2022 to 2026

Background Optimizing physical fitness (PF) and developing executive functions (EFs) is of great importance in preschool children. The link between PF, obtained through repetitive physical activity, and EFs is gaining increasing attention in recent years and we sought to systematically search the literature on the relationship between PF and EFs in preschool children published in the last five years. Methods Web of Science, Scopus, and PubMed were databases searched for the relevant literature. Original studies written in English and published in peer-reviewed journals including healthy children aged 3–6 years who were simultaneously tested for PF and EFs were considered eligible. …

Preserving Residual Kidney Function In Haemodialysis: Current Practices, Challenges, And Perspectives From Renal Clinicians, Lijun Zhong, Ulrich Steinwandel, Hugh Davies, Sara Bayes, Jagadish Jamboti, Hemant Kulkarni, Doris Chan

Research outputs 2022 to 2026

Background: Residual kidney function in patients receiving haemodialysis is associated with improved survival, reduced cardiovascular risk and better quality of life. Yet, clinical guidelines on its preservation are limited, and local practices remain unclear. Objectives: To explore current practices, perceptions and challenges related to residual kidney function preservation among renal clinicians. Design: Descriptive cross-sectional survey. Participants: Renal physicians and nurses working in hospital-based haemodialysis units across Western Australia. Measurements: Role-specific questionnaires were administered to renal physicians and nurses. Results: Eighty-four completed responses were received (physicians n = 25; nurses n = 59). Over half of physicians (56%, n = 14) …

Widespread Decline In The Abundance Of Sea Cucumber Assemblages In Atolls Of The Protected Rowley Shoals, Northwestern Australia, Inês Leal, Claire L. Ross, Simone Strydom, Richard D. Evans, Thomas H. Holmes, Graham J. Edgar, John K. Keesing

Research outputs 2022 to 2026

The Rowley Shoals, off northwestern Australia, are renowned as a biodiversity hotspot. This remote system comprises three atolls, Clerke, Imperieuse and Mermaid, which in recent years have been increasingly targeted by illegal fishing, a pressure rising across the Indo-Pacific. The objective of this study was to quantify recent changes in sea cucumber assemblages across the Rowley Shoals. We surveyed nine sea cucumber species at monitoring sites in 2018 and 2023 to assess changes in their abundance. Total assemblage densities declined significantly across all atolls and habitats. Documented seizures of illegally harvested holothurians by the Australian Fisheries Management Authority over this …

A Joint Effort: Stakeholders' Perspectives Of Medication Management Reviews In Australian Residential Aged Care, Rajendra Gyawali, Marea O'Donnell, Rachel Jenkins, Amy D. Nguyen, Lalit Yadav, Rosemary Saunders, Fiona J. Clay, Johanna I. Westbrook, Karla Seaman, Magdalena Z. Raban

Research outputs 2022 to 2026

Objective: Residential Medication Management Review (RMMR) is a government-funded pharmacist-led service to address medication-related problems, such as polypharmacy, which are prevalent in aged care. Despite known benefits, concerns remain about the service's effective implementation to benefit residents. We aimed to explore stakeholders' perspectives of the service and identify challenges and improvement opportunities. Method: A qualitative study was conducted using individual interviews and focus groups with 21 stakeholders, including general practitioners (GPs), a nurse practitioner, registered nurses, pharmacists and consumers. Audio transcripts of the discussions were thematically analysed using inductive coding. Results: Seven interconnected themes were identified, highlighting complexities in RMMR …

Dietary Flavonoid Intake And Psychological Well-Being – A Bidirectional Relationship, Alysha S. Thompson, Nicola P. Bondonno, Yan Lydia Liu, Farah Qureshi, Laura D. Kubzansky, Claudia Trudel-Fitzgerald, Julia K. Boehm, Eric B. Rimm, Aedín Cassidy

Research outputs 2022 to 2026

Background and aim: Higher dietary flavonoid intake has been associated with lower risks of mortality and major chronic disease, yet its relationship with psychological well-being (PWB), a key contributor to health and quality of life, remains unclear. This study aimed to investigate bidirectional associations between dietary flavonoid intake and two PWB facets: happiness (positive emotional state) and optimism (generalized expectation of positive outcomes). Specifically, we examined whether (1) overall flavonoid-rich dietary patterns (flavodiet score), (2) intake of specific flavonoid-rich foods, and (3) total flavonoid and subclass intakes were each associated with happiness and optimism over time. Methods: Data were drawn …

Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire

Research outputs 2022 to 2026

Globally, regional and remote communities are burdened by both an increased prevalence and worse prognosis of many infectious and chronic diseases. However, largely owing to logistical challenges, these communities are under-represented in clinical trials and research studies. As individuals from rural communities experience unique environmental exposures and risk factors for disease, immune phenotyping data collected from metropolitan populations may not be broadly generalizable. To address this, we present a workflow that enables the inclusion of resource-limited sites in high-parameter mass cytometry studies. In this approach, whole blood (WB) or peripheral blood mononuclear cells (PBMCs) are collected, stained fresh for surface …

Neutrophil Gelatinase-Associated Lipocalin And Neutrophil-To-Lymphocyte Ratio As Indicators Of Nephropathy In Type 2 Diabetic Mellitus Patients In Ghana: A Case-Control Study, Allwell Adofo Ayirebi, Wina Ivy Ofori Boadu, Stephen Twumasi, Samuel Kwarteng, Benedict Sackey, Lilian Antwi Boateng, Joseph Boachie, Samuel Essien-Baidoo, Daniel Nii Martey Antonio, John Agyemang Sah, Afua Marfowaa, Mayfair Adwapa Mpiani, Joachim Baba Domosie, Abiba Khalifah, Emmanuel Ekow Korsah, Ebenezer Senu, Eugene Arele Ansah, Joseph Yorke, Enoch Odame Anto

Research outputs 2022 to 2026

Introduction: Serum neutrophil gelatinase-associated lipocalin (sNGAL), a renal tubular marker, and neutrophil-to-lymphocyte ratio (NLR), a hematological inflammatory marker are two biomarkers that have recently received attention, because of their association with kidney disease. This study examined the diagnostic value sNGAL and NLR in type 2 diabetes mellitus (T2DM) patients with nephropathy. Materials and Methods: In this hospital-based case-control research, 97 T2DM participants and 70 healthy subjects were included. Participants' information was documented using a structured questionnaire and patient case records. Venous blood was drawn from each participant and early morning midstream urine samples were collected for blood and urine measurements …

Oral Ferrous Sulphate Supplementation Has Greater Efficacy, But Lower Tolerance Than Iron (Iii)-Hydroxide Polymaltose Complexes In Exercising Women With Low Iron Stores, Alannah Ka Mckay, Sophie Broome, Nicolin Tee, Kin Lui Yim, Marc Sim, Peter Peeling, Louise M. Burke

Research outputs 2022 to 2026

Background & Aims: Iron deficiency (ID) is a global health condition that predominately affects women. Although oral iron supplementation is an effective treatment strategy for this issue, gastrointestinal complaints are common, and if persistent, may lead to poor compliance. The efficacy of different iron formulations which claim to improve tolerance is unclear. This study assessed the efficacy and tolerability of ferrous sulphate (FS) and iron (III)-hydroxide polymaltose complex (IPC) supplementation in three different cohorts of women.. Methods: This study implemented a 12-week, single-blind, randomized controlled trial. Eligible participants had a serum ferritin concentration of <50 μg/L and met specific inclusion criteria to be enrolled to either the athlete, pre-menopausal or post-menopausal groups. Participants were randomized to receive FS (equivalent to 105 mg elemental iron) plus sodium ascorbate or IPC (equivalent to 100 mg elemental iron) daily. Venous blood samples were collected at baseline, 4-, 8- and 12-weeks of supplementation. A daily questionnaire was completed throughout the study period, documenting supplement tolerance (number and severity of symptoms), exercise load, menstrual characteristics, and supplement compliance. Results: Fifty-seven participants completed the intervention with a compliance rate of 94.9 % [range: 74.8-100 %]. A significant interaction between supplement and time was evident for ferritin (p < 0.001), where FS increased after 12 weeks (+109 %; p < 0.001) but no change was evident in IPC (+7 %; p = 0.727). No differences were detected between cohorts (p > 0.05). The IPC group had a …

Pleural Metastases From Acral Lentiginous Melanoma Diagnosed By Medical Thoracoscopy, Ad Rian Chong, Khai Lip Ng, Nai-Chien Huan, Nur Husna Mohd Aminudin, Fazilah Hassan, Kasuma Mohamed Nordin

Research outputs 2022 to 2026

Acral lentiginous melanoma (ALM) with pleural metastases is rare and under-recognised. We report an 86-year-old woman with progressive dyspnoea and pleuritic chest pain. 18 months ago, she was diagnosed with stage IIC ALM of the right heel, and was treated with wide local excision, but she declined adjuvant therapy. Imaging demonstrated a large left pleural effusion with diffuse pleural thickening, pulmonary mass, and hepatic metastases. Brownish pleural fluid, along with thoracoscopic identification of multiple pigmented nodules, led to a histologically confirmed diagnosis. Talc pleurodesis was performed for symptom control, and best supportive care was pursued. This case highlights the diagnostic …

Skeletal Muscle Health In Childhood Cancer Survivors: A Systematic Review And Meta-Analysis, Anna Maria Markarian, Dennis R. Taaffe, Daniel A. Galvão, Carolyn J. Peddle-Mcintyre, Jodie Cochrane Wilkie, Francesco Bettariga, Nicholas G. Gottardo, Mayank Dhamija, Santosh Valvi, Catriona M. Buchanan, Kerrie Graham, Robert U. Newton

Research outputs 2022 to 2026

Purpose: Childhood cancer survivors (CCS) are at risk of long-term skeletal muscle deficits following intensive therapies during critical periods of growth. This review aimed to synthesize approaches for assessing muscle quantity, quality, and function in CCS and to quantify deficits relative to healthy peers. Methods: A systematic search was conducted in CINAHL, Embase, PubMed, SPORTDiscus, and Web of Science from inception to June 2024, with an update in November 2025. Studies including CCS who had completed cancer treatment and reported measures of muscle quantity, quality, or physical function were eligible. A three-level mixed-effects model meta-analysis was conducted. Associations between muscle …

The Relationships Between Social Network Size, Loneliness And Personality In Individuals Living With A Neurological Condition: An Exploratory Study, Isabella Branson, Kate Turner, Mitchell Turner, Manja Laws, Leah Dempsey, Simon Laws, Mandy Stanley, Johnny Lo, Travis Cruickshank

Research outputs 2022 to 2026

Background: People living with a neurological condition often report having smaller social networks and less frequent social contact, leading to greater loneliness and worse quality of life. This study explored the relationships between personality traits, social network size (SNS) and perceived loneliness in this population. Methods: Sixty-eight individuals diagnosed with a neurological condition participated in this study. Perceived loneliness was assessed using the UCLA Loneliness Scale – Version 3, SNS was evaluated by the Social Network Index and personality traits were examined using the NEO Factor Five Inventory. Path analysis was conducted to determine if loneliness was negatively associated with …

Vibostolimab Coformulated With Pembrolizumab Versus Pembrolizumab Alone As Adjuvant Therapy For High-Risk Stage Iib–Iv Melanoma (Keyvibe-010): A Randomised, Double-Blind, Phase 3 Study, Reinhard Dummer, Jun Guo, Jason J. Luke, Matteo S. Carlino, Dirk Schadendorf, Muhammad A. Khattak, Axel Hauschild, Paolo A. Ascierto, Yu Chen, Sang Joon Shin, Piotr Rutkowski, Zhiguo Luo, Jing Chen, Gareth Rivalland, Corlia Coetzee, Antoni Ribas, Karmele Mujika, Gal Markel, Rodrigo U. Villarroel, Omer Dizdar, Christian Caglevic, Dmitri Grebennik, Kevin Donovan, Clemens Krepler, Georgina V. Long

Research outputs 2022 to 2026

Background Combination therapy with vibostolimab plus pembrolizumab has previously shown promising antitumor activity in melanoma. We aimed to evaluate the efficacy and safety of vibostolimab coformulated with pembrolizumab as adjuvant therapy for high-risk resected melanoma. Methods This randomised, double-blind, phase 3 study was done at 205 global sites (hospitals and cancer centres). Participants aged 12 years or older with surgically resected, stage IIB–IV cutaneous melanoma per the American Joint Committee on Cancer Cancer Staging Manual 2017 (8th edition), with no evidence of metastatic disease after resection, were randomly assigned (1:1) to receive vibostolimab 200 mg coformulated with pembrolizumab 200 mg …

Mentorship Practices And Perceptions Of Nursing Faculty At The Aga Khan University In Uganda: A Qualitative Study, Mary Namuguzi, Sarah Nakaziba, Shamim Namukasa, Carolyne Namukwaya, Dinah Kassaman, Arnold Mwanzu, Jackline Estomihi Kiwelu, Duncan Osuka, Nazahed Mkiramweni, Ahmed Sarki

School of Nursing & Midwifery, East Africa

Background Mentorship of new faculty helps to reduce the challenges associated with their new roles, as some lack knowledge of teaching pedagogies. This study assessed the mentorship experiences regarding practices and perceptions of new nursing and midwifery faculty at the Aga Khan University School of Nursing and Midwifery (SONAM) in Uganda.

Methodology This study used a phenomenological design. Data were collected in semistructured interviews with 11 participants, and data saturation was reached. Data were organized with NVivo 12 Pro and analyzed using framework analysis.

Findings The main themes that emerged were mentorship practices, perceptions about mentorship, and proposed mentorship guidelines. …

Evolving U.S. And Chinese International Development Policy: Institutions, Strategies, And Global Impact, Julian Kai Lehto

Social Sciences

This paper is inspired by, and meant to understand, recent changes in global policy towards foreign aid and international development. 2025 saw one of the biggest changes to international development in decades, when President Donald Trump’s new administration made the decision to effectively shut down the United States Agency for International Development (USAID). At the same time, China has been taking on a growing role in foreign aid and development over the last decade. Chinese projects like the Belt and Road Initiative (BRI) have become globally significant. This paper will explore the changing impacts and influence of both the U.S. …

Exploring The Mental Health Impacts Of Dating Experiences For Racial And Ethnic Minorities At A Predominantly White Institution, Maya Sánchez, Mylina Garza, Emma Chung

Communication Studies

The present study examined the mental health implications of racial and ethnic minorities’ dating experiences at a Predominantly White Institution (PWI). The authors conducted retrospective interviews with 20 minority-identifying college students that attend California Polytechnic State University, San Luis Obispo. Three primary themes emerged from the conducted research. 1) Feeling excluded from racialized beauty standards threatens self-worth, 2) struggling to find romantic belonging limits emotional safety in relationships and navigating cultural differences in dating produces identity hyperawareness. This study also offers interesting theoretical and practical implications. Theoretically, findings display the communication maintenance of identity to how romantic involvement impacts …

The Guardian The Month Of March 2026, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the Month of March 2026. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Pollinators Exhibit For Paso Robles Children’S Museum, Isabelle Moll, Matthew Moore, Joseph Hovanesian, Evan Stock, Matthew Wiecking

Mechanical Engineering

This report documents the design and development of an interactive pollination exhibit created for the Paso Robles Children’s Museum as part of the Mechanical Engineering Senior Project program. The goal of the project was to design a durable, safe, and engaging educational exhibit that introduces children to the role of pollinators in local ecosystems and agriculture through hands-on play. The final design features a triple-track system with rolling bee elements and a central pollen ball pathway that demonstrates how pollinators move between flowers and return resources to the hive. The exhibit incorporates visual feedback and locally inspired design elements to …

Mel’S: A Modern Soup Brand Reshaping The Industry, Melody Chaerin Braunstein

Graphic Communication

My senior project focuses on the primary stages of creating a soup brand through market/trend research and branding. During this project, I aim to better understand the process of creating a brand, and the organization needed to flow through different stages.

My project hopes to analyze the current market and determine what it takes to create a successful product that stands out. My goal is to have a cohesive vision of the brand that creates a better baseline for later steps, such as graphic and packaging design, social media, and marketing.

Reframing Greek Life: The Ifc Story, Neal Raghav Parthasarathy

Graphic Communication

Organizations like the Interfraternity Council (IFC) have a hard time with telling a comprehensive story of the positive impact they are making to Cal Poly as well as to the SLO community. Our fraternities spend thousands of hours collectively to serve the local communities, and we collect metrics on volunteer hours, how much funds we raised, etc. However, these are usually communicated in a disjointed way through social media, emails and so on. So the various community stakeholders don’t get the full picture, and the negative perceptions around partying far outweigh the good we are doing. 

As IFC president, I …

Early Insights From A Multi-Centre National Stroke Surveillance Initiative In Tanzania, Sarah Shali Matuja, Azan Nyundo, Emmanuel Assey, Joel Bwelemo, Marieke Dekker, Sarah Urasa, Emanuel Makarius, Peter Kishimbo, Philip Adebayo, Paschal Ruggajo

Internal Medicine, East Africa

Background: Stroke is a leading cause of death and disability globally, with sub-Saharan Africa, bearing the greatest burden. Tanzania has only one active stroke registry, limiting evidence-based care and policy development. We aimed to expand the registry into a multi-centre study across eight major tertiary hospitals to generate baseline data for a national stroke registry.

Methods: From January to August 2024, we analysed de-identified data from adults (≥18 years) admitted with a World Health Organisation defined stroke. Data collected included demographics, risk factors, imaging, and in-hospital mortality. Logistic regression identified predictors of mortality.

Results: A total of 1000 patients were …

Bayesian Machine Learning Enables Discovery Of Risk Factors For Hepatosplenic Multimorbidity Related To Schistosomiasis, Yin-Cong Zhi, Victor Anguajibi, John Oryema, Betty Nabatte, Christopher Opio, Narcis Kabatereine, Goylette Chami

Internal Medicine, East Africa

One in 25 deaths worldwide is related to liver disease, and often with multiple hepatosplenic conditions. Yet, little is understood of the risk factors for hepatosplenic multimorbidity, especially in the context of chronic infections. We present a novel Bayesian multitask learning framework to jointly model 45 hepatosplenic conditions assessed using point-of-care B-mode ultrasound for 3155 individuals aged 5-91 years within the SchistoTrack cohort across rural Uganda, where chronic intestinal schistosomiasis is endemic. We identify distinct and shared biomedical, socioeconomic, and spatial risk factors for individual conditions and hepatosplenic multimorbidity, and introduce methods for measuring condition dependencies as risk factors. Notably, …

Disseminated Iatrogenic Upper Gastrointestinal Kaposi Sarcoma Following Prolonged Steroid Use In A Patients With Crohn's Disease: A Case Report, Glory Makupa, Furaha Serventi, Leila Mwakipunda, Godwin Nnko, Edwin Liwa, Salum Lidenge, Ayesiga Herman, Lilian Gasper, Amos Mwasamwaja, Beatrice Kombole

Internal Medicine, East Africa

Background Kaposi sarcoma is a malignant vascular neoplasm caused by human herpesvirus-8. It is mostly seen in immunocompromised individuals, particularly those with human immunodeficiency virus/acquired immunodeficiency syndrome or organ transplants. Cutaneous and mucosal Kaposi sarcoma manifestation is common; however, Kaposi sarcoma may involve the visceral organs. Iatrogenic or drug-induced Kaposi sarcoma may develop in immunocompromised patients undergoing immunosuppressive medication. It is quite uncommon for patients with inflammatory bowel diseases on immunosuppressive medication to develop intestinal Kaposi sarcoma. This case report describes the clinical presentation of steroid-induced disseminated upper gastrointestinal Kaposi sarcoma in a patient with underlying Crohn’s disease and examines …