Digital Commons Network^™

The Effect Of Prenatal Cigarette Smoke Exposure And Adult High-Fat/High-Fructose Diet On Liver Triglyceride Levels, Toni A. Adedokun, Isaiah Burciaga, Megan Jacobs, Katelyn Chism, Anna-Lee Harris, Kristen Overton, Selma Podbicanin, Andrew Potts, Rachel Neal, Cynthia Corbitt

The Cardinal Edge

Prenatal cigarette smoke exposure (CSE) is associated with chronic metabolic disease in adulthood, including obesity, type 2 diabetes, and metabolic dysfunction-associated fatty liver disease. Maternal cigarette smoking reduces uterine and placental blood flow, limiting nutrients and oxygen supply to the fetus. According to the Developmental Origins of Health and Disease hypothesis, these conditions may cause developmental adaptations that are maladaptive in calorie-rich environments. We hypothesized that gestational CSE would sensitize affected offspring to the effects of an adulthood high-fat (40 kcal%), high fructose (20 kcal%) diet. C57BL/6J mice were exposed either to filtered room air (sham) or the smoke generated …

Depression, Belonging, And Self-Censorship About Palestine Among Arab Americans, Ghadir Habeeb, Amanda Jiang, Batool Alderawi, Yara Mekawi, Nadia Al-Dajani

The Cardinal Edge

Background: As a result of exposure to traumatic media depicting the Gaza genocide, many Arab Americans are moved to speak up in support of Palestine. Due to the suppression of pro-Palestinian advocacy, however, many Arab Americans self-censor as a defense mechanism, which can alleviate distress but can also exacerbate depressive symptoms. Belongingness may serve as a protective factor against the negative effects of self-censorship. Centering Arab Americans’ experiences, this study examines the relationship between self-censorship and depression, as well as the role of belongingness in this association.

Method: Arab Americans adults recruited through Qualtrics Survey Panels completed questionnaires assessing self-censorship, …

An Examination Of The Relationships Between Types Of Strain And Substance Misuse Among Queer Adults​, Mckenzie T. Nguyen, Katelyn Mcmahon

The Cardinal Edge

Current research has paid particular attention to outcomes of different strains using samples of sexual and gender minority (SGM) youth; however, minimal research has examined Agnew's (1992) General Strain Theory (GST) using samples of SGM adults. Using a path analysis, this study seeks to investigate how different strains - including financial strain, relationship strain, and victimization - are predictive of drug misuse, and if those effects are mediated by negative mental health outcomes. The study utilizes Meyer's (2016) Generations Study and includes a sample of 1,518 SGM Americans. Results indicate that only financial strain is partially mediated by negative emotions, …

Aristotle And The Proslavery Writings Of The Antebellum South, Ace Farris

The Cardinal Edge

This paper explores how nineteenth-century Southern intellectuals appropriated and adapted Aristotle’s ancient defense of slavery to legitimize racial slavery in the antebellum United States. Although Aristotle’s theory of “natural slavery” emerged from the social and economic conditions of classical Greece, where enslaved people constituted essential components of the household, Southern thinkers tailored his argument to justify the peculiar institution. The paper begins by outlining Aristotle’s defense of slavery in his Politics, which states that some individuals naturally lack the capacity for rational deliberation, thereby benefiting from enslavement. Then, it traces how the American South’s investment in classical education allowed …

Fear And Freedom: California Gay Bars In The 1960s, Bridget L. Kelley

The Cardinal Edge

This article explores the interactions between gay bars, queer people, and police in California in the 1960s. The gay bar served as both a place of community and safety while paradoxically being a site of oppression suffered at the hands of law enforcement. These conflicting experiences made gay bars sites of both fear and freedom. Arrest practices, plain clothes policing, raid practices, and monetary manipulation made the gay bar a space of danger. However, the resistance of queer patrons against police brutality made it a space where one could express their queerness and fight for change.

The Kennedy Familys' Influence On The Passage Of The Immigration And Nationality Act Of 1965, Jillian Wallshield

The Cardinal Edge

This paper covers the influence of the Kennedy Family on immigration policy in the United States. United States immigration legislation changed dramatically in the 1960s with the passage of the Immigration and Nationality Act of 1965 (sometimes called the Hart-Cellar Act). This shift was caused primarily by the political work of prominent figures like John F. Kennedy, and, later, Edward Kennedy. Edward Kennedy in particular is examined through his influence on Lyndon B. Johnson, the President under which the Immigration and Nationality Act was passed. This position is supported through the examination of relevant public speeches, private telephone calls, and …

Hallucinogens For Mood And Anxiety Disorders: A Critical Review Of Psychedelic-Assisted Therapies, Georgia Chlebek

The Cardinal Edge

In quite a few people worldwide, there are several mental disorders that prevent the brain from operating in the “proper” way, depression, anxiety, and post-traumatic stress disorder (PTSD) being among the most common. Luckily, there are several medications that are produced and used to treat these disorders, but some medications are hard to access, and others simply don’t help the patient. Firstly, these medications take time to study and prove safe for public use, though in some cases time is not readily available. In other cases, these medications are going through shortages and becoming increasingly difficult for patients to access …

Determination Of Trace Amounts Of Pb2+ And Cu2+ Ions In The Ohio River With Anodic Stripping Voltammetry And Flame Atomic Absorption Spectroscopy To Test Water Contamination From Factories., Eliana Purcell

The Cardinal Edge

In this project, water near factories in Rubbertown, Louisville, KY were tested to see if a significant enough amount of waste is deposited in the Ohio River that the concentrations of Pb2+ and Cu2+ exceed the maximum contaminant levels the World Health Organization (WHO) and the United States Environmental Protection Agency (EPA) have set in place. Waste from industrial factories may contain contaminants that have negative effects on aquatic ecosystems and even human health, so two potentially harmful metal ions were tested. The concentration of Cu2+ in water samples was detected through flame atomic absorption spectroscopy (FAAS), and the concentration …

Leaf Droppage Delayed In Sugar Maple Trees On An Urban To Rural Gradient, Isabella S. Bastien, Isabella Bastien

The Cardinal Edge

This study investigates the timing of leaf abscission in Sugar Maple (Acer saccharum) trees along an urban-to-rural gradient in Louisville, Kentucky, to determine how proximity to urban environments influences leaf drop. We hypothesized that urban trees would retain their leaves longer than suburban or rural trees due to environmental stressors and tested this using weekly leaf collection and canopy cover measurements from three locations—urban, suburban, and rural. Results showed that urban trees exhibited delayed leaf drop and slower canopy opening compared to suburban and rural trees. These findings suggest that urban stressors significantly alter tree phenology, which may signal underlying …

Disrupted Nuclear Function And Nucleocytoplasmic Transport In Parkinson’S Disease, Ichiro M. Matoba

The Cardinal Edge

No abstract provided.

Asimina Triloba (L.) Dunal: The Complete Story Of America’S Forgotten Fruit, Autumn M. Howard

The Cardinal Edge

Asimina triloba, commonly known as the pawpaw, is a unique and historically significant native fruit tree of the eastern United States. This research paper explores the taxonomy, botanical description, distribution, habitat requirements, ecological interactions, economic importance, and reproductive biology of A. triloba. The species is distinguished by its tropical-flavored fruits, adaptation to temperate climates, and reliance on clonal reproduction and specific insect pollinators. While offering promising opportunities for sustainable agriculture and riparian restoration, A. triloba faces challenges related to limited seed dispersal, susceptibility to certain pests and diseases, and the presence of neurotoxic compounds. Despite its historical importance …

Development And Preliminary Pressure Control Validation Of Woundwatch: Npwt System With Remote Monitoring Capabilities, Swetha Senthil Nathan

The Cardinal Edge

Chronic wounds, including diabetic foot ulcers, pressure sores, and venous leg ulcers, affect over 40 million individuals worldwide and are often complicated by delayed healing due to limited access to continuous monitoring. Negative Pressure Wound Therapy (NPWT) is an established treatment that promotes wound healing through controlled sub-atmospheric pressure. However, conventional NPWT systems lack real-time physiological feedback and require frequent in-person follow-ups, limiting their effectiveness in remote or low-resource settings. This study presents WoundWatch, a portable, low-cost NPWT device that integrates real-time temperature, humidity, and pressure sensing with wireless data transmission via an IoT platform. The system includes a vacuum …

Lamin A/C And Linc Complex Expression Affects Nuclei's Mechanical Properties And Functions In Osteosarcoma, Shridha Rajeswar

The Cardinal Edge

The nucleus has long been simplified in the field of biology, despite being an important organelle. Until recently, it has been commonly depicted as a simple sphere located at the center of a cell, responsible mainly for regulating protein synthesis. However, current research indicates that the linkers of the nucleoskeleton and cytoskeleton (LINC) complexes, the pillars of nuclear architecture, play a critical role in maintaining nuclear integrity and function. These complexes interact with proteins, such as Lamins, that modulate responses to biomechanical stimuli through the regulation of gene expression. As such, when these structures are downregulated, they can contribute to …

The Silent Epidemic: How E-Cigarettes And Policy Gaps Endanger Public Health, Fizzah Syed, Saumya Sikhwal, Priya Viswakumar

The Cardinal Edge

No abstract provided.

The Developing Role Of Ai In Modern Engineering Research, Rianna Pais

The Cardinal Edge

No abstract provided.

Targeting Glioblastoma: Mechanistic And Clinical Perspectives From Uofl Research, Swetha Senthil Nathan

The Cardinal Edge

Glioblastoma (GBM) remains one of the most aggressive and treatment-resistant brain tumors, with median survival lingering at 12–15 months despite surgery, radiation, and chemotherapy. This article explores cutting-edge research and clinical efforts at the University of Louisville aimed at improving GBM treatment outcomes. Dr. Joseph Chen investigates the tumor microenvironment, revealing how physical properties such as stiffness and porosity drive GBM cell proliferation, migration, and resistance to apoptosis. His lab’s findings suggest that porosity, rather than stiffness alone, may be a more accurate predictor of tumor invasion and progression-free survival. Additionally, his research highlights the role of hyaluronic acid and …

Sound, Speech, And Synapses: Rebuilding The Brain Through Neuroplasticity, Sireen Khader

The Cardinal Edge

No abstract provided.

From "Come Talk", The Rattler

The Rattler

Vol. 114, Iss. 2

Generation Z'S Rising Interest In "Grandma" Hobbies, Isabella Pizzoferrato, The Rattler

The Rattler

Vol. 114, Iss. 2

U.S. Arctic Sea Lines Of Communication (Sloc): The Imperative For A Maritime Complex And Corridor In The Bering Region, Samuel A. Krakower, Troy J. Bouffard

Joint Force Quarterly

This paper examines the current American capacity to defend its newfound Sea Lines of Communication in the North Pacific and Arctic Oceans. The history, and importance, of Sea Lines of Communication trace back to great naval strategists such as Rear Admiral Alfred Thayer Mahan and Sir Julian Corbett, and consistent protection of these maritime corridors in times of war and peace led to the success of the United States. As the Arctic Region emerges as a new theater of geopolitical importance, the United States finds itself significantly disadvantaged or "strategically handicapped” in terms of presence, capability, and proximity to defend …

What’S Old Is New: Lsco Casualty Evacuation In The 21st Century, Jonathan S. Pederson

Joint Force Quarterly

A future Large Scale Combat Operation (LSCO) fight will present new challenges and require different strategies and tactics than currently employed to adequately evacuate and treat the large numbers of expected casualties. Methods used in the past will be resurrected and revamped, and new innovations will be required.

Ukraine, The U.S. Defense Industrial Base, And The Elusive Crisis-Era Munitions Production Surge, Bryce Loidolt

Joint Force Quarterly

“Ukraine, the U.S. Defense Industrial Base, and the Elusive Crisis-Era Munitions Production Surge” by Bryce Loidolt examines why U.S. efforts to rapidly increase munitions production during Russia’s war in Ukraine produced uneven results. While crisis-era authorities, funding, and contracting flexibility allowed the Department of War to move quickly after 2022, this article argues that post-crisis actions alone did not determine surge success. Instead, variation in production increases across key munitions - Stinger, Javelin, GMLRS, and PAC-3 MSE, was largely driven by pre-crisis procurement decisions and associated investments in capacity, supply chains, and obsolescence management. Drawing on historical analysis and case …

Evaluating Assistive Technology-Mediated Hepatitis B Education On At-Risk Behaviours Among In-School Adolescents With Hearing Impairment In Oyo State, Nigeria, Suen. E. Olalekanmi, J. O. Odelola, O. O. Isaiah

The 2026 Assistive Technology for Persons with Intellectual and Physical Disabilities Conference

Background: Adolescents with hearing impairment experience heightened vulnerability to health risks, largely due to limited access to accurate, accessible, and comprehensible health information. Communication barriers often restrict their understanding of disease prevention, resulting in inadequate health literacy and increased engagement in behaviours that may expose them to preventable infections such as HB. Despite the availability of effective vaccines and preventive measures, HB remains a significant public health concern in Nigeria. This situation underscores the urgent need for researchers, educators, and healthcare professionals to develop and prioritise inclusive health education strategies that address the unique communication needs of adolescents with hearing …

State-Level Policies Addressing Maternal Mental Health Conditions: How Texas Compares, Nicole H. Cirino

Journal of Applied Research on Children: Informing Policy for Children at Risk

In 2019, maternal mental health conditions (MMHCs) were the most common underlying cause of pregnancy-related death in Texas, contributing to over 20% of all deaths. Furthermore, it is estimated that 13.2% of all Texas women who gave birth in 2019 had an untreated MMHC. The most common MMHCs leading to mortality were depressive disorders, substance use disorders, bipolar and psychotic disorders. In 2022, the maternal mortality rate for Black women was over twice the rate for White and Hispanic women and three times the rate for Asian women. In addition to maternal harms, untreated perinatal mental health conditions are associated …

Overcoming Syphilis In Pregnancy, Martha Rac

Journal of Applied Research on Children: Informing Policy for Children at Risk

No abstract provided.

Full Issue - Mend V.4, Project Mend

Mend

No abstract provided.

Editors - Mend V.4, Project Mend

Mend

No abstract provided.

Anonymous Woman (Love, Feminism, And Literay Perspectives), Angelo Sedillo

Mend

No abstract provided.

Monsters Under The Bed, John Steiner

Mend

No abstract provided.

Permission To Grieve, Rebekha Nilsen

Mend

No abstract provided.