Digital Commons Network^™

Policing Fiscal Corruption: Tax Crime And Legally Corrupt Institutions In The United Kingdom, Branislav Hock

Law and Contemporary Problems

No abstract provided.

Fsec Meeting Minutes January 30, 2023, University Of Rhode Island Faculty Senate

Faculty Senate Executive Committee Minutes

No abstract provided.

Loss-Of-Function KCa2.2 Mutations Abolish Channel Activity, Young-Woo Nam, Mohammad Asikur Rahman, Grace Yang, Razan Orfali, Meng Cui, Miao Zhang

Pharmacy Faculty Articles and Research

Small-conductance Ca²⁺-activated potassium channels subtype 2 (K_Ca2.2, also called SK2) are operated exclusively by a Ca²⁺-calmodulin gating mechanism. Heterozygous genetic mutations of K_Ca2.2 channels have been associated with autosomal dominant neurodevelopmental disorders including cerebellar ataxia and tremor in humans and rodents. Taking advantage of these pathogenic mutations, we performed structure-function studies of the rat K_Ca2.2 channel. No measurable current was detected from HEK293 cells heterologously expressing these pathogenic K_Ca2.2 mutants. When co-expressed with the K_Ca2.2_WT channel, mutations of the pore-lining amino acid residues (I360M, Y362C, G363S …

Sensitivity Of Puff Dynamics And Airborne Droplet Nuclei Distribution To Variations In Violent Expiration Events, M. Allahyari, K. Liu (刘凯), J. Salinas, ‪Nadim Zgheib, S. Balachandar

Mechanical Engineering Faculty Publications

We use large eddy simulations to investigate the puff and droplet dynamics from violent expiratory events such as coughs and sneezes in the first few seconds following an ejection. For each of the eleven simulations considered, over 60,000 droplets are ejected and individually tracked using the point-particle Euler–Lagrange approach. We test the sensitivity of the puff and droplet dynamics to various parameters including the ejection volume, momentum, and orientation. We also explore the effect of the mouth shape on the aforementioned dynamics by considering elliptical and circular inlet cross-sections. The results from the simulations compare favorably with a recent theoretical …

Chronic Anti-Coagulation Therapy Reduced Mortality In Patients With High Cardiovascular Risk Early In Covid-19 Pandemic, Mohamed S Zaghloul, Momodou Jammeh, Andrew Gibson, Suhong Luo, Kelley Chadwick-Mansker, Qianjin Liu, Yan Yan, Mohamed A Zayed

2020-Current year OA Pubs

BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with provoked thrombo-inflammatory responses. Early in the COVID-19 pandemic this was thought to contribute to hypercoagulability and multi-organ system complications in infected patients. Limited studies have evaluated the impact of therapeutic anti-coagulation therapy (AC) in alleviating these risks in COVID-19 positive patients. Our study aimed to investigate whether long-term therapeutic AC can decrease the risk of multi-organ system complications (MOSC) including stroke, limb ischemia, gastrointestinal (GI) bleeding, in-hospital and intensive care unit death in COVID-19 positive patients hospitalized during the early phase of the pandemic in the United States.

METHODS: A retrospective analysis …

The Free Press Vol. 54, January 01-30-2023, Kelly Ledsworth

Free Press, The

Surviving a Snow Day--Iranian Women Demand Change--Financial Goal Setting--The Husky Hub

What We Don't Need To Prove But Need To Do In Multidisciplinary Treatment And Care In Huntington's Disease: A Position Paper, Alzbeta Mühlbӓck, Marleen Van Walsem, Martha Nance, Astri Arnesen, Kirsty Page, Alexandra Fisher, Manon Van Kampen, Angela Nuzzi, Roy Limpert, Hanne Ludt Fossmo, Travis Cruickshank, Ruth Veenhuizen

Research outputs 2022 to 2026

Background: Huntington’s disease is a complex neurodegenerative hereditary disease with symptoms in all domains of a person’s functioning. It begins after a healthy start in life and leads through the relentless progression over many years to complete care dependency and finally death. To date, the disease is incurable. The long progressive complex nature of the disease demands multiple disciplines for treatment and care of patient and family. These health care providers need inter- and multidisciplinary collaboration to persevere and be efficacious in this devastating disease trajectory. Discussion: The position paper outlines current knowledge and experience alongside the experience and consensus …

January 30, 2023

The Gavel Gazette

No abstract provided.

Literature Review: Orientation And Mobility Assistive Technology For Students With Visual Impairment, Ida Alfa Nerri, Endang Purbaningrum, Asri Wijiastuti, Sri Joeda Andajani, Md Abu Bakor Siddik

Journal of ICSAR

The development of increasingly sophisticated technology is accompanied by the discovery of new assistive devices that should be accessible to all people, including the blind in order to maintain or improve functions so as to improve welfare. This study uses a literature review method with descriptive analysis by analyzing 20 articles. The purpose of this research is to examine more related to assistive technology for the blind in navigating indoors and outdoors including buildings and the accessibility of public services. The literature search was carried out through an electronic search for publications from ERIC, Researchgate, Spingerlink, Sage, Science Direct, Google …

The Perception Of Special Education Teachers Towards The Involvement Of Audiologist In Special Education School, Mohd Hanafi Mohd Yasin, Mohd Mokhtar Tahar, Suziyani Mohamad, Nurul Ezza Aleyza Binti Rasilah, Rabaishah Azirun

Journal of ICSAR

Audiologists is an individual that has close connection with deaf and hearing impairment students. This research is done to study the perception of the special education teachers on the involvement of audiologists in special education school. In this research, quantitative data which is questionnaire is used as the research instrument. The data obtained were analyzed using Microsoft Excel XLstat. The total of 165 teachers that are included in this research through snow-balling sampling. Results shown that 149 (90.8 percent) of the teachers agreed that the role of audiologists is vital to improve the special education quality in Malaysia. In general, …

Barriers And Perceptions Of Disabled University Students On Online Learning Methods During The Covid-19 Pandemic, Nurul Aqilah Arifin, Mohd Hanafi Mohd Yasin, Sinta Yuni Susilawati, Rabaishah Azirun

Journal of ICSAR

The purpose of this study is to find out in more detail about the obstacles faced by students with OKU UKM while following online learning as well as their views in particular on effective online learning methods during this pandemic season. Next, the study was conducted quantitatively using survey method. An online questionnaire (google form) was used in this study as a research instrument which in total contains 18 items. The study sample was randomly selected in groups according to the rate for each category. It consists of 30 OKU students from 47 OKU students who are active in the …

Nanoscale Hafnium Metal-Organic Frameworks Enhance Radiotherapeutic Effects By Upregulation Of Type I Interferon And Tlr7 Expression, Eunseo Choi, Madeleine R. Landry, Nathan Pennock, Katherine Weinfurter, Multiple Additional Authors

Chemistry Faculty Publications and Presentations

Recent preclinical and clinical studies have highlighted the improved outcomes of combination radiotherapy and immunotherapy. Concurrently, the development of high-Z metallic nanoparticles as radiation dose enhancers has been explored to widen the therapeutic window of radiotherapy and potentially enhance immune activation. In this study, we evaluate folate-modified hafnium-based metal-organic frameworks (HfMOF-PEG-FA) in combination with imiquimod, a TLR7 agonist, as a well-defined interferon regulatory factor (IRF) stimulator for local antitumor immunotherapy. The enhancement of radiation dose deposition by HfMOF-PEG-FA and subsequent generation of reactive oxygen species (ROS) deregulates cell proliferation and increases apoptosis. HfMOF-PEG-FA loaded with imiquimod (HfMOF-PEG-FA@IMQ) increases DNA double-strand …

Lcd 322: Disorders Of Speech, Yael Neumann

Open Educational Resources

No abstract provided.

Blastoid B-Cell Neoplasms: Diagnostic Challenges And Solutions, Lianqun Qiu, Sa A Wang, Guilin Tang, Wei Wang, Pei Lin, Jie Xu, C Cameron Yin, Mahsa Khanlari, L Jeffrey Medeiros, Shaoying Li

Faculty, Staff and Student Publications

Blastoid B-cell neoplasms mainly include B-lymphoblastic leukemia/lymphoma (B-ALL), blastoid mantle cell lymphoma, and high-grade B-cell lymphoma with blastoid morphologic features (blastoid HGBL). Distinguishing blastoid HGBL from B-ALL can be challenging and we previously developed six-point flow cytometry-focused and three-point immunohistochemistry-focused scoring systems to aid in differential diagnosis. However, the six-point scoring system was derived from bone marrow cases and occasional cases may have a misleading score using either system. In this study, we assessed 121 cases of blastoid-HGBL (37 BM and 84 extramedullary) to validate the six-point scoring system in all tissue types and to further compare the two scoring …

Extracellular Matrix (Ecm) And Fibrosis In Adipose Tissue: Overview And Perspectives, Kai Sun, Xin Li, Philipp E Scherer

Faculty, Staff and Student Publications

Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy expansion of adipose tissue in response to over nutrition. In obese adipose-depots, hypoxia stimulates multiple pro-fibrotic signaling pathways in different cell populations, thereby inducing the overproduction of the ECM components, including collagens, noncollagenous proteins, and additional enzymatic components of ECM synthesis. As a consequence, local fibrosis develops. The result of fibrosis-induced mechanical stress not only triggers cell necrosis and inflammation locally in adipose tissue but also leads to system-wide lipotoxicity and insulin resistance. A better understanding …

Additive And Synergistic Relations Of Early Mother–Child And Caregiver–Child Interactions And Socioeconomic Outcomes In Adulthood, Robert Duncan, Inga Nordgren, Sara A. Schmitt, Deborah Lowe Vandell

Purdue Center for Early Learning Faculty and Staff Publications

Prior theoretical and empirical studies have linked the first 3 years of children's life with later life outcomes. One primary explanation is the critical role these experiences play in children's early brain development (including their early language and cognitive abilities) and subsequent schooling achievement. The current study is a registered report with two complementary research objectives: (1) examine to what extent stimulating and responsive interactions with mothers and nonparental caregivers during the first 3 years of life show additive or synergistic associations with key socioeconomic outcomes in adulthood (i.e., educational attainment, salary, and employment status), and (2) examine to what …

Protecting New Hoosiers And Their Parents, Inga Nordgren, Robert Duncan, Kate Kester, Shelley Macdermid Wadsworth

Center for Families Publications

No abstract provided.

Predicting Suicidal And Self-Injurious Events In A Correctional Setting Using Ai Algorithms On Unstructured Medical Notes And Structured Data, Hongxia Lu, Alex Barrett, Albert Pierce, Jianwei Zheng, Yun Wang, Chun Chiang, Cyril Rakovski

Mathematics, Physics, and Computer Science Faculty Articles and Research

Suicidal and self-injurious incidents in correctional settings deplete the institutional and healthcare resources, create disorder and stress for staff and other inmates. Traditional statistical analyses provide some guidance, but they can only be applied to structured data that are often difficult to collect and their recommendations are often expensive to act upon. This study aims to extract information from medical and mental health progress notes using AI algorithms to make actionable predictions of suicidal and self-injurious events to improve the efficiency of triage for health care services and prevent suicidal and injurious events from happening at California's Orange County Jails. …

Sawah Sebagai Media Healing Pada Masyarakat Modern, Dani Setiawan, Siti Murtinigsih

Multikultura

Sawah merupakan salah satu lingkungan pertanian hidup yang terus menjadi perhatian berbagai pihak. Sawah tidak hanya menjadi suatu komoditas tempat penghasil pangan untuk memenuhi kebutuhan gizi makro. Sawah mempunyai makna tinggi secara metafisika yaitu sawah menyimpan kandungan partikel oksigen yang dibutuhkan tubuh setiap manusia termasuk sebagian orang yang sering melakukan bermain ke sawah. Sawah pada masa sekarang dimaknai sebagai tempat untuk berelaksasi psikis, bahkan untuk melakukan healing yang diyakini sawah mempunyai energi hijau dengan ketataruangan terbuka dengan udara bersih dan kesejukannya. Sawah bagi sebagian masyarakat modern dibutuhkan untuk mendapatkan ketenangan dan menggantikan suasana kota yang penuh dengan persoalaan dinamika kehidupan. …

Beyond Bribery: Exploring The Intimate Interconnections Between Corruption And Tax Crimes, Diane Ring, Costantino Grasso

Law and Contemporary Problems

No abstract provided.

Developing A Working Model To Fight Fiscal Corruption: The Nexus At Which Tax Crimes And Corruption Meet, Pietro Sorbello, Stephen Holden

Law and Contemporary Problems

No abstract provided.

Wave Your Little Hand And Whisper So Long Dearie: Proffering An Overdue Goodbye To Microunits In The Performing Arts, Amanda Joos

Law and Contemporary Problems

No abstract provided.

Genetic Association And Causal Inference Between Lung Function And Venous Thromboembolism, Qiaoyun Zhang, Xiaoyu Zhang, Jie Zhang, Mengyang Jiang, Yiqiang Zhang, Deqiang Zheng, Lijuan Wu, Wei Wang, Baoguo Wang, Youxin Wang

Research outputs 2022 to 2026

Background: Previous studies have indicated that lower lung function is related to a higher risk of venous thromboembolism (VTE). However, causal inferences may be affected by confounders, coheritability or reverse causality. We aimed to explore the causal association between lung function and VTE. Methods: Summary data from public genome-wide association studies (GWAS) for lung function and VTE were obtained from published meta-analysis studies and the FinnGen consortium, respectively. Independent genetic variables significantly related to exposure were filtered as proxy instruments. We adopted linkage disequilibrium score regression (LDSC) and two-sample Mendelian randomization (MR) analyses to infer the genetic backgrounds and causal …

A Non-Reference Evaluation Of Underwater Image Enhancement Methods Using A New Underwater Image Dataset, Ashraf Saleem, Sidike Paheding, Nathir Rawashdeh, Ali Awad, Navjot Kaur

Michigan Tech Publications, Part 1

The rise of vision-based environmental, marine, and oceanic exploration research highlights the need for supporting underwater image enhancement techniques to help mitigate water effects on images such as blurriness, low color contrast, and poor quality. This paper presents an evaluation of common underwater image enhancement techniques using a new underwater image dataset. The collected dataset is comprised of 100 images of aquatic plants taken at a shallow depth of up to three meters from three different locations in the Great Lake Superior, USA, via a Remotely Operated Vehicle (ROV) equipped with a high-definition RGB camera. In particular, we use our …

Bayesian Nonparametric Modelling Of Conditional Multidimensional Dependence Structures, R Barone, L Dalla Valle

School of Engineering, Computing and Mathematics

In recent years, conditional copulas, that allow dependence between variables to vary according to the values of one or more covariates, have attracted increasing attention. However, the literature mainly focused on the bivariate case, since the constraints on the multivariate copulas correlation matrices would make the specifications of covariates arduous. In high dimension, vine copulas offer greater flexibility compared to multivariate copulas, since they are constructed using bivariate copulas as building blocks. We present a novel inferential approach for multivariate distributions, which combines the flexibility of vine constructions with the advantages of Bayesian nonparametrics, not requiring the specification of parametric …

An Analysis Of Cultural Values, Religiosity And Family Member's Caregiving On The Positive Appraisal Of Caring For The Elderly, Fayron R. Epps

Dissertations

The stress and burden experienced by the family caregiver during the caregiving experience has been widely researched and established among the literature. Limited research exists on the impact of cultural values, religiosity and family caregiving on the caregiver's positive appraisal of caring for a dependent elderly family member. Therefore, the purpose of this study was to examine the influence of cultural values and religiosity on the positive appraisal of caregiving among African American, Hispanic and Caucasian caregivers for dependent elderly family members. A predictive correlational study design was employed to examine the relationship amongst variables for 69 African-American, Hispanic and …

Estimating The Effects Of The Ada Amendments Act On The Hiring And Termination Of Individuals With Disabilities, Using New Disability Categorizations, Patrick Button, Philip Armour, Simon Hollands

Upjohn Institute Working Papers

Disability discrimination laws are often used to potentially increase employment for individuals with disabilities. However, legal theory and empirical economics research do not provide conclusive answers as to how expansions in disability discrimination laws affect economic outcomes, namely hiring rates, for individuals with disabilities. We estimate the effect of the ADA Amendments Act (ADAAA) on employment transitions: hirings and terminations for individuals with disabilities relative to those without disabilities. To calculate employment transitions, we use data from the Survey of Income and Program Participation (SIPP). We also use the SIPP to develop additional measures and categorizations of disability based on …

Sepsis Early Recognition And Response: Education And Simulation To Increase Knowledge And Confidence In Associate Degree Nursing Students, Susan G. Bryant

Dissertations

Sepsis kills more than 250,000 people every year in the United States. Immediate treatment is crucial for best patient outcomes but sepsis can be challenging to identify. Nurses may miss signs of sepsis and delay life-saving treatment. The purpose of this quality improvement project was to determine whether an instructional presentation on introduction to sepsis followed by a high fidelity sepsis simulation scenario would improve knowledge and confidence in early recognition of and response to signs of sepsis for final semester associate degree nursing (ADN) students. Tanner's Clinical Judgment Model was used as the theoretical framework for this project. The …

Impact Of Authentic Leadership On Team Psychological Safety As Mediated By Relationship Quality, Mechelle J. Plasse

Dissertations

Leadership is a dynamic process with a far-reaching impact. Leadership is the process of guiding a group of individuals towards the achievement of a common goal. Healthcare leaderships looks to guide staff towards the common goal of positive patient outcomes. The literature has demonstrated that staff outcomes related to the health of their work environment can impact patient outcomes. A contributor to the health of the work environment is the relational tone of the unit; this tone is partly shaped by the skill and philosophy of the leader. Relational dynamics can influence several processes, including psychological safety which is a …

Healthcare Provider's Perceived Self-Efficacy In Hpv Vaccination Hesitancy Counseling And Hpv Vaccination Acceptance, Ikponmwosa Osaghae, Charles Darkoh, Onyema Greg Chido-Amajuoyi, Wenyaw Chan, Paige Padgett Wermuth, Mala Pande, Sonia A Cunningham, Sanjay Shete

Faculty, Staff and Student Publications

BACKGROUND: HPV vaccine hesitancy is a key contributor to the sub-optimal HPV vaccination uptake in the United States. We aimed to determine the association between healthcare providers' self-efficacy in HPV vaccination hesitancy counseling and HPV vaccination acceptance after initial and follow-up counseling sessions.

METHODS: Population-based cross-sectional study of healthcare providers (HCPs) practicing in Texas. Logistic regression analyses were used to determine the odds of HPV vaccination acceptance by vaccine-hesitant patients. Additionally, generalized estimating equations were used to compare HPV vaccination acceptance by hesitant patients after follow-up versus initial counseling sessions.

RESULTS: 1283 HCPs completed the survey with a mean (SD) …