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Pregnancy Advance Directives, Joan H. Krause Feb 2023

Pregnancy Advance Directives, Joan H. Krause

Cardozo Law Review

No abstract provided.


Massage Therapy For Children, Adolescents, And Young Adults: Clinical Delivery And Effectiveness In Hematology And Oncology, Samuel N. Rodgers-Melnick, Mandy Bartolovich, Neha J. Desai, Smitha Hosahalli Vasanna, Amma Owusu-Ansah, Sanjay P. Ahuja, Jeffery A. Dusek, David W. Miller Feb 2023

Massage Therapy For Children, Adolescents, And Young Adults: Clinical Delivery And Effectiveness In Hematology And Oncology, Samuel N. Rodgers-Melnick, Mandy Bartolovich, Neha J. Desai, Smitha Hosahalli Vasanna, Amma Owusu-Ansah, Sanjay P. Ahuja, Jeffery A. Dusek, David W. Miller

Student Scholarship

Background: Children, adolescents, and young adults with hematologic and/or oncologic conditions experience multiple, significant symptoms (e.g., pain, stress, and anxiety), which may be addressed by nonpharmacologic approaches such as massage therapy (MT). The purpose of this study was to describe the clinical delivery of MT provided by a certified pediatric massage therapist and assess effectiveness in two patient groups: those with sickle cell disease (SCD) or hematologic and/or oncologic conditions excluding SCD (HemOnc). Methods: Investigators conducted a retrospective review of MT sessions provided to patients 0–39 years with hematologic and/or oncologic conditions at a large pediatric academic medical center. Results: …


Editorial: Green Chemistry Biocatalysis, Barry J. Ryan, Gary T. Henehan, Bekir E. Eser, Ning Li, Zheng Guo, Gemma K. Kinsella Feb 2023

Editorial: Green Chemistry Biocatalysis, Barry J. Ryan, Gary T. Henehan, Bekir E. Eser, Ning Li, Zheng Guo, Gemma K. Kinsella

Articles

Editorial on the Research Topic: Green chemistry biocatalysis


Cascading Effects Of Cover Crops On The Subsequent Cash Crop Defense Against The Polyphagous Herbivore Fall Armyworm (Spodoptera Frugiperda), Adegboyega Fajemisin, Alexis Racelis, Rupesh Kariyat Feb 2023

Cascading Effects Of Cover Crops On The Subsequent Cash Crop Defense Against The Polyphagous Herbivore Fall Armyworm (Spodoptera Frugiperda), Adegboyega Fajemisin, Alexis Racelis, Rupesh Kariyat

Entomology and Plant Pathology Faculty Publications and Presentations

Recent studies have started to show that the benefits of cover crops can cascade to the cash crop growing seasons. However, the impact of cover crops on the subsequent cash crop defense against herbivores is not well understood. To test this, we conducted a field and laboratory study to assess the possible cascading effects of cover crops such as Vigna unguiculata, Sorghum drummondii, Raphanus sativus, and Crotalaria juncea on the subsequent cash crop (Sorghum bicolor) defense against the notorious polyphagous herbivore fall armyworm (Spodoptera frugiperda) across three farms in the Lower Rio Grande Valley. Our field …


Major Questions And An Emergency Question Doctrine: The Biden Student Debt Case Study Of Pretextual Abuse Of Emergency Powers, Jed Handelsman Shugerman Feb 2023

Major Questions And An Emergency Question Doctrine: The Biden Student Debt Case Study Of Pretextual Abuse Of Emergency Powers, Jed Handelsman Shugerman

Faculty Scholarship

The major question doctrine tries to address one problem, the Imperial Executive, by escalating another, the Imperial Judiciary. This article proposes a solution, with the Biden Student Debt Waiver as a case study: An “emergency question” doctrine.

This emergency questions doctrine would apply when the executive relies on a statutory emergency clause or invokes an emergency in its application of a statutory provision. As a matter of statutory interpretation, the emergency question doctrine would follow the two most important steps of the major question approach: 1) relying on purpose and context to clarify and limit the scope of open-ended emergency …


Policing & The Problem Of Physical Restraint, Steven Arrigg Koh Feb 2023

Policing & The Problem Of Physical Restraint, Steven Arrigg Koh

Faculty Scholarship

The Fourth Amendment of the U.S. Constitution prohibits unreasonable “seizures” and thus renders unlawful police use of excessive force. On one hand, this definition is expansive. In the U.S. Supreme Court’s 2021 Term, in Torres v. Madrid, the Court clarified that a “seizure” includes any police application of physical force to the body with intent to restrain. Crucially, Chief Justice Roberts’ majority opinion emphasized that police may seize even when merely laying “the end of a finger” on a layperson’s body. And yet, the Supreme Court’s Fourth Amendment totality-of-the-circumstances reasonableness balancing test is notoriously imprecise—a “factbound morass,” in the famous …


Just Kidding? The Problem Of Unenforceable Waivers Of Liability, Anthony J. Sebok Feb 2023

Just Kidding? The Problem Of Unenforceable Waivers Of Liability, Anthony J. Sebok

Articles

No abstract provided.


Utilizing Design Thinking To Enhance Wellbeing In Interdisciplinary Courses: A Positive Social Psychology Approach, Areej Elsayary Feb 2023

Utilizing Design Thinking To Enhance Wellbeing In Interdisciplinary Courses: A Positive Social Psychology Approach, Areej Elsayary

All Works

Design thinking is considered to be a positive social psychology intervention. Students who practice using the design thinking process during their coursework will most likely solve personal problems that improve their well-being. This study investigates the impact of using the design thinking process in interdisciplinary courses to enhance students' well-being through developing mindsets that enable them to solve their problems and set personal goals unconsciously. A modified PERMA-PH model is used to guide this study. The PERMA included Positive Emotions, Negative Emotions, Engagement, Relationship, Meaning and Purpose, and Accomplishments, the "PH" (future plans and health) was added to the PE …


Myo/Nog Cells Give Rise To Myofibroblasts During Epiretinal Membrane Formation In A Mouse Model Of Proliferative Vitreoretinopathy., Mara Crispin, Jacquelyn Gerhart, Alison Heffer, Mark Martin, Fathma Abdalla, Arturo Bravo Nuevo, Nancy J Philp, Ajay E Kuriyan, Mindy George-Weinstein Feb 2023

Myo/Nog Cells Give Rise To Myofibroblasts During Epiretinal Membrane Formation In A Mouse Model Of Proliferative Vitreoretinopathy., Mara Crispin, Jacquelyn Gerhart, Alison Heffer, Mark Martin, Fathma Abdalla, Arturo Bravo Nuevo, Nancy J Philp, Ajay E Kuriyan, Mindy George-Weinstein

PCOM Scholarly Works

PURPOSE: Myo/Nog cells are the source of myofibroblasts in the lens and synthesize muscle proteins in human epiretinal membranes (ERMs). In the current study, we examined the response of Myo/Nog cells during ERM formation in a mouse model of proliferative vitreoretinopathy (PVR).

METHODS: PVR was induced by intravitreal injections of gas and ARPE-19 cells. PVR grade was scored by fundus imaging, optical coherence tomography, and histology. Double label immunofluorescence localization was performed to quantify Myo/Nog cells, myofibroblasts, and leukocytes.

RESULTS: Myo/Nog cells, identified by co-labeling with antibodies to brain-specific angiogenesis inhibitor 1 (BAI1) and Noggin, increased throughout the eye with …


Wayne E. Sabbe Arkansas Soil Fertility Studies 2022, Nathan A. Slaton, Mike Daniels Feb 2023

Wayne E. Sabbe Arkansas Soil Fertility Studies 2022, Nathan A. Slaton, Mike Daniels

Arkansas Agricultural Experiment Station Research Series

Rapid technological changes in crop management and production require that the research efforts be presented in an expeditious manner. The contributions of soil fertility and fertilizers are major production factors in all Arkansas crops. The studies described within will allow producers to compare their practices with the university’s research efforts. Additionally, soil-test data and fertilizer sales are presented to allow comparisons among years, crops, and other areas within Arkansas.


Genomic Or Non-Genomic? A Question About The Pleiotropic Roles Of Vitamin D In Inflammatory-Based Diseases, Michael F. Holick, Luciana Mazzei, Sebastián García Menéndez, Virna Margarita Martín Giménez, Fatme Al Anouti, Walter Manucha Feb 2023

Genomic Or Non-Genomic? A Question About The Pleiotropic Roles Of Vitamin D In Inflammatory-Based Diseases, Michael F. Holick, Luciana Mazzei, Sebastián García Menéndez, Virna Margarita Martín Giménez, Fatme Al Anouti, Walter Manucha

All Works

Vitamin D (vit D) is widely known for its role in calcium metabolism and its importance for the bone system. However, various studies have revealed a myriad of extra-skeletal functions, including cell differentiation and proliferation, antibacterial, antioxidant, immunomodulatory, and anti-inflammatory properties in various cells and tissues. Vit D mediates its function via regulation of gene expression by binding to its receptor (VDR) which is expressed in almost all cells within the body. This review summarizes the pleiotropic effects of vit D, emphasizing its anti-inflammatory effect on different organ systems. It also provides a comprehensive overview of the genetic and epigenetic …


Metagenomic Analysis Of The Outdoor Dust Microbiomes: A Case Study From Abu Dhabi, Uae, Lina Maloukh, Yousef Nazzal, Alagappan Kumarappan, Fares Howari, Lakshmi Kesari Ambika, Rihab Yahmadi, Manish Sharma, Jibran Iqbal, Ahmed A. Al-Taani, Imen Ben Salem, Cijo M. Xavier, Muhamad Naseem Feb 2023

Metagenomic Analysis Of The Outdoor Dust Microbiomes: A Case Study From Abu Dhabi, Uae, Lina Maloukh, Yousef Nazzal, Alagappan Kumarappan, Fares Howari, Lakshmi Kesari Ambika, Rihab Yahmadi, Manish Sharma, Jibran Iqbal, Ahmed A. Al-Taani, Imen Ben Salem, Cijo M. Xavier, Muhamad Naseem

All Works

Outdoor dust covers a shattered range of microbial agents from land over transportation, human microbial flora, which includes pathogen and commensals, and airborne from the environment. Dust aerosols are rich in bacterial communities that have a major impact on human health and living environments. In this study, outdoor samples from roadside barricades, safety walls, and fences (18 samples) were collected from Abu Dhabi, UAE and bacterial diversity was assessed through a 16S rRNA amplicon next generation sequencing approach. Clean data from HiSeq produced 1,099,892 total reads pairs for 18 samples. For all samples, taxonomic classifications were assigned to the OTUs …


Allelic Discrimination Of Vitamin D Receptor Polymorphisms And Risk Of Type 2 Diabetes Mellitus: A Case-Controlled Study, Amal Ahmed Mohammed, Dina M.Abo El-Matty, Rola Abdel-Azeem, Khaled Raafat, Mona A. Hussein, Amira R. El-Ansary, Wael Hafez, Hatem Ahmed Hassan, Nourelhuda Ahmed Nassar, Nora Mahmoud Selim, Doaa Ghaith, Amal A.El Kholy, Soha M. Abd El Salam, Fatme Al Anouti, Alaa S. Wahba Feb 2023

Allelic Discrimination Of Vitamin D Receptor Polymorphisms And Risk Of Type 2 Diabetes Mellitus: A Case-Controlled Study, Amal Ahmed Mohammed, Dina M.Abo El-Matty, Rola Abdel-Azeem, Khaled Raafat, Mona A. Hussein, Amira R. El-Ansary, Wael Hafez, Hatem Ahmed Hassan, Nourelhuda Ahmed Nassar, Nora Mahmoud Selim, Doaa Ghaith, Amal A.El Kholy, Soha M. Abd El Salam, Fatme Al Anouti, Alaa S. Wahba

All Works

(1) Background: Type 2 diabetes mellitus (T2DM) is one of the rapidly growing healthcare problems, and several vitamin D receptor (VDR) polymorphisms seem to modulate the risk of T2DM. Our research was designed to investigate the allelic discrimination of VDR polymorphisms and T2DM occurrence risk. (2) Methods: This case-control research included 156 patients with T2DM and 145 healthy control subjects. Most of the study population were males 56.6% vs. 62.8% in the case and control groups, respectively. Genotyping for VDR single nucleotide polymorphisms (SNPs), rs228570 (Fok1), rs7975232 (Apa1), and rs1544410 (Bsm1) was compared between both groups. (3) Results: There was …


Intelligent Health Care And Diseases Management System: Multi-Day-Ahead Predictions Of Covid-19, Ahed Abugabah, Farah Shahid Feb 2023

Intelligent Health Care And Diseases Management System: Multi-Day-Ahead Predictions Of Covid-19, Ahed Abugabah, Farah Shahid

All Works

The rapidly growing number of COVID-19 infected and death cases has had a catastrophic worldwide impact. As a case study, the total number of death cases in Algeria is over two thousand people (increased with time), which drives us to search its possible trend for early warning and control. In this paper, the proposed model for making a time-series forecast for daily and total infected cases, death cases, and recovered cases for the countrywide Algeria COVID-19 dataset is a two-layer dropout gated recurrent unit (TDGRU). Four performance parameters were used to assess the model’s performance: mean absolute error (MAE), root …


Oral Ibrexafungerp For Vulvovaginal Candidiasis Treatment: An Analysis Of Vanish 303 And Vanish 306, Oluwatosin Goje, Ryan Sobel, Paul Nyirjesy, Steven R Goldstein, Mark Spitzer, Brooke Faught, Shelagh Larson, Thomas King, Nkechi E Azie, David Angulo, Jack D Sobel Feb 2023

Oral Ibrexafungerp For Vulvovaginal Candidiasis Treatment: An Analysis Of Vanish 303 And Vanish 306, Oluwatosin Goje, Ryan Sobel, Paul Nyirjesy, Steven R Goldstein, Mark Spitzer, Brooke Faught, Shelagh Larson, Thomas King, Nkechi E Azie, David Angulo, Jack D Sobel

Department of Obstetrics and Gynecology Faculty Papers

Background: Ibrexafungerp is a novel antifungal treatment for acute vulvovaginal candidiasis (VVC). Using pooled data from two phase three studies (VANISH 303 and 306) in the treatment of acute VVC, this analysis sought to determine the effectiveness of ibrexafungerp in various patient subgroups that may impact outcomes. Materials and Methods: Data from VANISH 303 (NCT03734991) and VANISH 306 (NCT03987620) evaluating ibrexafungerp 300 mg twice daily (BID) for 1 day versus placebo, were pooled and analyzed to determine clinical cure rate, clinical improvement, and mycological cure at the test-of-cure visit (day 11 ± 3) and symptom resolution …


How To Read Ellen White's Writings Today, Denis Kaiser Feb 2023

How To Read Ellen White's Writings Today, Denis Kaiser

Faculty Publications

No abstract provided.


Dairy Knowledge Bowl Packet, Extension Feb 2023

Dairy Knowledge Bowl Packet, Extension

UNH Cooperative Extension

No abstract provided.


Understanding And Advancing The Preservation Trades, Jada Lindblom Ph.D., Scott Slattery, Molly Donovan Feb 2023

Understanding And Advancing The Preservation Trades, Jada Lindblom Ph.D., Scott Slattery, Molly Donovan

UNH Cooperative Extension

Showing a collective interest in the preservation and restoration trades workforce, four statewide preservation nonprofits (representing NY, VT, NH, and ME) joined forces in 2021 to create the Northeast Regional Initiative for the Preservation Trades. The initiative’s aim is to better understand this issue and develop courses of action to foster a more robust and sustainable preservation trades workforce. In 2022, specialists from UNH Cooperative Extension’s Community and Economic Development team partnered with this initiative to lead a multi-methods research project consisting of a survey, interviews, and focus groups with trades professionals, preservation specialists, workforce development professionals, educators, and other …


Understanding And Advancing The Preservation Trades (2-Page View)), Jada Lindblom Ph.D., Scott Slattery, Molly Donovan Feb 2023

Understanding And Advancing The Preservation Trades (2-Page View)), Jada Lindblom Ph.D., Scott Slattery, Molly Donovan

UNH Cooperative Extension

Showing a collective interest in the preservation and restoration trades workforce, four statewide preservation nonprofits (representing NY, VT, NH, and ME) joined forces in 2021 to create the Northeast Regional Initiative for the Preservation Trades. The initiative’s aim is to better understand this issue and develop courses of action to foster a more robust and sustainable preservation trades workforce. In 2022, specialists from UNH Cooperative Extension’s Community and Economic Development team partnered with this initiative to lead a multi-methods research project consisting of a survey, interviews, and focus groups with trades professionals, preservation specialists, workforce development professionals, educators, and other …


The Impact Of Objectively Recorded Smartphone Usage And Emotional Intelligence On Problematic Internet Usage, Sameha Alshakhsi, Khansa Chemnad, Mohamed Basel Almourad, Majid Altuwairiqi, John Mcalaney, Raian Ali Feb 2023

The Impact Of Objectively Recorded Smartphone Usage And Emotional Intelligence On Problematic Internet Usage, Sameha Alshakhsi, Khansa Chemnad, Mohamed Basel Almourad, Majid Altuwairiqi, John Mcalaney, Raian Ali

All Works

This study examined the effects of gender, age, objective smartphone usage data, and Emotional Intelligence (EI) on Problematic Internet Use (PIU) and its components (obsession, neglect, and control disorder). The study relied on objective data of smartphone usage as a representative of technology use collected by a monitoring application of smartphone usage. PIU and EI were measured through the Problematic Internet Usage Questionnaire short form (PIUQ-SF-6) and Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF), respectively. The current cross-sectional study was carried out with 268 participants (Female: 61.6%, ages from 15 to 64) from ten different countries. The analysis was performed using …


Engineering A Microbiosphere To Clean Up The Ocean – Inspiration From The Plastisphere, Khulood A. Alnahdi, Laila W. Alali, Mezna K. Suwaidan, M. Kalim Akhtar Feb 2023

Engineering A Microbiosphere To Clean Up The Ocean – Inspiration From The Plastisphere, Khulood A. Alnahdi, Laila W. Alali, Mezna K. Suwaidan, M. Kalim Akhtar

All Works

Plastic is a ubiquitous material that has become an essential part of our lives. More than one hundred million tons of plastic has accumulated in the world’s oceans as a result of poor waste management. This plastic waste gradually fragments into smaller pieces known as microplastics and nanoplastics. These small plastic particles can cause significant damage to marine ecosystems, and negatively impact human health. According to a recent review of international patents, the majority of ocean-cleaning inventions are limited to microplastics larger than 20 μm. Furthermore, such technologies are ineffective for nanoplastics, which measure less than 1000 nm, or even …


Towards Machine Learning-Based Fpga Backend Flow: Challenges And Opportunities, Imran Taj, Umer Farooq Feb 2023

Towards Machine Learning-Based Fpga Backend Flow: Challenges And Opportunities, Imran Taj, Umer Farooq

All Works

Field-Programmable Gate Array (FPGA) is at the core of System on Chip (SoC) design across various Industry 5.0 digital systems—healthcare devices, farming equipment, autonomous vehicles and aerospace gear to name a few. Given that pre-silicon verification using Computer Aided Design (CAD) accounts for about 70% of the time and money spent on the design of modern digital systems, this paper summarizes the machine learning (ML)-oriented efforts in different FPGA CAD design steps. With the recent breakthrough of machine learning, FPGA CAD tasks—high-level synthesis (HLS), logic synthesis, placement and routing—are seeing a renewed interest in their respective decision-making steps. We focus …


Comments On The Draft Final Butte Priority Soils Operable Unit (Bpsou) Temporary Construction Surface Water Performance Standards Variance Request For Future Remedial Elements (Fresow) Projects (Dated December 7, 2022), Nikia Greene Feb 2023

Comments On The Draft Final Butte Priority Soils Operable Unit (Bpsou) Temporary Construction Surface Water Performance Standards Variance Request For Future Remedial Elements (Fresow) Projects (Dated December 7, 2022), Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Sars-Cov-2-Specific T Cell And Humoral Immunity In Individuals With And Without Hiv In An African Population: A Prospective Cohort Study, Owen Ngalamika, Salum J. Lidenge, Marie Claire Mukasine, Musonda Kawimbe, Patrick Kamanzi, John R. Ngowi, Julius Mwaiselage, For Yue Tso Feb 2023

Sars-Cov-2-Specific T Cell And Humoral Immunity In Individuals With And Without Hiv In An African Population: A Prospective Cohort Study, Owen Ngalamika, Salum J. Lidenge, Marie Claire Mukasine, Musonda Kawimbe, Patrick Kamanzi, John R. Ngowi, Julius Mwaiselage, For Yue Tso

School of Medicine Faculty Publications

Objectives: To longitudinally compare SARS-CoV-2-specific T cell and humoral immune responses between convalescent individuals who are HIV-positive (HIV+) and HIV-negative (HIV-). Methods: We conducted enzyme-linked immunospots to determine the SARS-CoV-2-specific T cell responses to spike and nucleocapsid, membrane protein, and other open reading frame proteins (NMO), whereas an immunofluorescence assay was used to determine the humoral responses. Participants were sampled at baseline and after 8 weeks of follow-up. Results: Individuals who are HIV- had significantly more T cell responses to NMO and spike than individuals who are HIV+ at baseline, P-value = 0.026 and P-value = 0.029, respectively. At follow-up, …


Colorblind Nationalism And The Limits Of Citizenship, Ming Hsu Chen Feb 2023

Colorblind Nationalism And The Limits Of Citizenship, Ming Hsu Chen

Cardozo Law Review

Policymakers and lawyers posit formal citizenship as the key to inclusion. Rather than presume that formal citizenship will necessarily promote equality, this Article examines the relationship between citizenship, racial equality, and nationalism. It asks: What role does formal citizenship play in excluding noncitizens and Asian, Latinx, and Muslim citizens racialized as foreigners? What effects does it have on the meaning of being American as a non-White citizen? The Article argues that commitments to colorblind equality and democratic self-governance of the nation stand in contradiction to aspirations to protect all persons within the nation. Consequently, individual rights designed to remedy racial …


Right For Any Reason, Jeffrey M. Anderson Feb 2023

Right For Any Reason, Jeffrey M. Anderson

Cardozo Law Review

The chances of winning an appeal in federal court are slim. One reason for that is an array of rules of appellate review that “stack the deck” in favor of the appellee and the lower court’s judgment. One such rule of review is “right for any reason,” the rule that an appellee may defend a lower court’s judgment on any grounds supported by the record—even grounds that the lower court rejected or ignored. The judgment may be right, even if the reasons are wrong. In 1924, the Supreme Court described the rule as “settled”—and felt no need to cite authority …


Foreseeability Conventions, John Fabian Witt, Morgan Savige Feb 2023

Foreseeability Conventions, John Fabian Witt, Morgan Savige

Cardozo Law Review

How has the foreseeability standard survived its critics? Law relies on foreseeability to solve hard legal problems in a vast array of doctrinal fields. But for a century and more, critics have pilloried the standard as hopelessly indeterminate. Decisionmakers, observe the critics, can characterize virtually any consequence as either foreseeable or unforeseeable. It all depends on how one tells the story. This Article explains the conundrum of foreseeability’s puzzling persistence by offering a novel account of how foreseeability has flourished in fields like tort, contract, and crime. Foreseeability has survived and flourished, the Article proposes, not because it carries determinate …


Automated In Vivo High-Resolution Imaging To Detect Human Papillomavirus-Associated Anal Precancer In Persons Living With Hiv, David Brenes, Alex Kortum, Jennifer Carns, Tinaye Mutetwa, Richard Schwarz, Yuxin Liu, Keith Sigel, Rebecca Richards-Kortum, Sharmila Anandasabapathy, Michael Gaisa, Elizabeth Chiao Feb 2023

Automated In Vivo High-Resolution Imaging To Detect Human Papillomavirus-Associated Anal Precancer In Persons Living With Hiv, David Brenes, Alex Kortum, Jennifer Carns, Tinaye Mutetwa, Richard Schwarz, Yuxin Liu, Keith Sigel, Rebecca Richards-Kortum, Sharmila Anandasabapathy, Michael Gaisa, Elizabeth Chiao

Faculty, Staff and Students Publications

INTRODUCTION: In the United States, the effectiveness of anal cancer screening programs has been limited by a lack of trained professionals proficient in high-resolution anoscopy (HRA) and a high patient lost-to-follow-up rate between diagnosis and treatment. Simplifying anal intraepithelial neoplasia grade 2 or more severe (AIN 2+) detection could radically improve the access and efficiency of anal cancer prevention. Novel optical imaging providing point-of-care diagnoses could substantially improve existing HRA and histology-based diagnosis. This work aims to demonstrate the potential of high-resolution microendoscopy (HRME) coupled with a novel machine learning algorithm for the automated, in vivo diagnosis of anal precancer. …


Association Of Lifestyle Behaviors With Non-Alcoholic Fatty Liver Disease And Advanced Fibrosis Detected By Transient Elastography Among Hispanic/Latinos Adults In The Us, Natalia I Heredia, Xiaotao Zhang, Maya Balakrishnan, Jessica P Hwang, Aaron P Thrift Feb 2023

Association Of Lifestyle Behaviors With Non-Alcoholic Fatty Liver Disease And Advanced Fibrosis Detected By Transient Elastography Among Hispanic/Latinos Adults In The Us, Natalia I Heredia, Xiaotao Zhang, Maya Balakrishnan, Jessica P Hwang, Aaron P Thrift

Faculty, Staff and Students Publications

OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent liver disease, with the highest prevalence observed in the U.S. among Hispanic/Latino adults. While physical activity and dietary behaviors have established protective associations with NAFLD and its severity, these associations have not been well-characterized in Hispanic/Latino adults. The purpose of this study was to assess the association of lifestyle behaviors with NAFLD and advanced fibrosis in US Hispanic/Latino adults.

DESIGN: We selected all Hispanic/Latino adults from the 2017-2018 National Health and Nutrition Examination Survey (NHANES). NAFLD was defined as CAP ≥285 dB/m, and advanced fibrosis as liver stiffness measurements ≥8.6 …


Rates Of Antimicrobial Resistance In Helicobacter Pylori Isolates From Clinical Trial Patients Across The Us And Europe, Francis Mégraud, David Y Graham, Colin W Howden, Ernest Trevino, Alice Weissfeld, Barbara Hunt, Neila Smith, Eckhard Leifke, William D Chey Feb 2023

Rates Of Antimicrobial Resistance In Helicobacter Pylori Isolates From Clinical Trial Patients Across The Us And Europe, Francis Mégraud, David Y Graham, Colin W Howden, Ernest Trevino, Alice Weissfeld, Barbara Hunt, Neila Smith, Eckhard Leifke, William D Chey

Faculty, Staff and Students Publications

INTRODUCTION: Guidelines recommend that proton pump inhibitor-based triple regimens with clarithromycin not be used for Helicobacter pylori infection in areas where clarithromycin resistance is ≥15%, or in patients with prior macrolide use. Up-to-date information on local resistance patterns is limited, especially in the US. Here, we report resistance rates to antibiotics commonly used to treat H. pylori from a large study conducted in the US and Europe (pHalcon-HP).

METHODS: Gastric mucosal biopsies were collected from adult participants with H. pylori infection during screening. Minimum inhibitory concentrations were determined via agar dilution for clarithromycin, amoxicillin, and metronidazole, with breakpoints ≥1 μg/mL, …