Digital Commons Network^™

Slp 594.01: Graduate Seminar-Counseling, Jenna R. Griffin

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Slp 640.V50: Swallowing Disorders, Jane E. Reynolds

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Slp 640.B01: Swallowing Disorders, Jane E. Reynolds

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Wage And Cost Study Of Oregon Assisted Living And Residential Care Providers, 2022, Ozcan Tunalilar, Sarah Dys, Paula Carder, Diana Jacoby

Institute on Aging Publications

Senate Bill 703 directed Oregon Department of Human Services (ODHS) to conduct a study of licensed residential care (RCF) and assisted living (ALF) facilities, including those with a memory care (MC) endorsement, to evaluate: a) Total cost to provide care to residents, b) the sufficiency of the Medicaid reimbursement paid to facilities to meet the total cost of care, and c) the average compensation paid to direct care workers by the facilities by geographic region. ODHS contracted with the Institute on Aging (IOA) at Portland State University (PSU) to conduct a study to achieve these three objectives. In the fall …

Paxlovid-Induced Tacrolimus Toxicity In The Treatment Of Covid-19: A Case Report., Stephanie Michael, Rachel Heilbronner, Christopher M Lloyd, Howard W Levitin

Pharmacy Articles

Paxlovid^TM (nirmaltrelvir/ritonavir) received emergency use authorization from the Food and Drug Administration (FDA) in December 2021 to treat coronavirus disease 2019 (COVID-19). Given the actions of Paxlovid on cytochrome P450-3A4 (CYP3A4) enzymes, it is imperative to check for potential drug-drug interactions before prescribing. We describe a case in which the common emergency department presentation of generalized weakness was found to be caused by interactions between Paxlovid and a patient's home medications resulting in tacrolimus toxicity.

The Employment Situation Of Veterans: January 2023, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

Veteran employment trends and statistics among various demographics during January 2023

The Interfaith Dental Program Of Michigan, William J. Danaher, Jr M.Div, Phd

The Journal of the Michigan Dental Association

In the wake of the fall of Kabul in August 2021, hundreds of thousands of Afghan refugees found temporary shelter at American airbases, prompting non-profit organizations and faith communities to assist in their resettlement. The Rev. Dr. William J. Danaher Jr. details the efforts of Christ Church Cranbrook and the Muslim Unity Center in Michigan to address the healthcare needs of Afghan refugees, particularly in dental care. Facing language and cultural barriers, they established an Interfaith Refugee Dental Program that successfully provided critical dental services to these refugees. The program's collaborative and humanitarian approach has improved the refugees' well-being and …

Retail Landscape Changes May Affect Kroger-Albertsons Deal, Ed Fox, Emily Cotton, Laura O'Laughlin

Marketing Research

No abstract provided.

Effective Farm Management Promotes Native Amf And Benefit Organic Farming Systems, Pushpa Soti, Rupesh R. Kariyat, Alexis Racelis

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Highlights

• Agricultural practices have significant influence on the AMF community dynamics.

• Soil nutrients regulate AMF spore abundance and diversity.

• Using grass cover crops can promote native AMF in farms.

Abstract

Using soil inoculants containing naturally occurring beneficial microorganisms has become a popular practice in sustainable agriculture. However, an understanding of the environmental variables that affect plant-microbe interactions and the benefit of using commercial inoculum is relatively sparse. To address this, we examined the efficiency of three different methods to inoculate AMF (Arbuscular Mycorrhizal Fungi) in organic vegetable farms in south Texas: cover cropping, application of farm-produced (indigenous) AMF inoculum, …

Inspire : Vol 6, Issue 2, Department Of Medicine

INSPIRE – Department of Medicine Archives

• Message from the Chair
• Medicine at National and International Forums
• Pan Arab Union of Neurological Societies
• APPNA Merit HIV Awareness, Prevention and Education Project in Pakistan
• International Women Leaders Summit
• Early Career Researcher Training Grant – The Association of Commonwealth Universities
• Life Saving Training in Sindh under PLSP by AKU
• In-depth- featuring Dr Osman Faheem
• Featured Person: Dr. Saadia Farooqui | Senior Manager “You’ll never know how strong you are, until being strong is the only choice you have”
• Poem Section - If by Rudyard Kipling
• What are Academics Around the World Reading This Month?
• Publications

Patient-Level And System-Level Determinants Of Stroke Fatality Across 16 Large Hospitals In Ghana And Nigeria: A Prospective Cohort Study, Fred S. Sarfo, Onoja M. Akpa, Bruce Ovbiagele, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi, Godwin Ogbole, Philip Adebayo

Internal Medicine, East Africa

Background: Every minute, six indigenous Africans develop new strokes. Patient-level and system-level contributors to early stroke fatality in this region are yet to be delineated. We aimed to identify and quantify the contributions of patient-level and system-level determinants of inpatient stroke fatality across 16 hospitals in Ghana and Nigeria.

Methods: The Stroke Investigative Research and Educational Network (SIREN) is a multicentre study involving 16 sites in Ghana and Nigeria. Cases include adults (aged ≥18 years) with clinical and radiological evidence of an acute stroke. Data on stroke services and resources available at each study site were collected and analysed as …

Does Mainstream Brca Testing Affect Surgical Decision-Making In Newly-Diagnosed Breast Cancer Patients?, Quratul Ain, Caroline Richardson, Miriam Mutebi, Angela George, Zoe Kemp, Jennifer E. Rusby

General Surgery, East Africa

Background: Germline pathogenic variants mutations) in the BRCA1 and BRCA2 genes cause an increased risk of breast cancer and ovarian cancer. Mainstream cancer genetic testing (MCG) was introduced for breast cancer patients in our unit in 2013. Non-geneticist clinicians have been trained to offer genetic testing during initial treatment planning. We assessed the impact of timely test results on surgical decision-making.

Methods: Women who had undergone mainstream genetic testing for breast cancer between September 2013 and September 2018 were identified from a prospective database. Surgical data were collected retrospectively.

Results: 580 eligible women had mainstream genetic testing. …

Physical Activity And Exercise For Hot Flashes: Trigger Or Treatment?, Sarah Witkowski, Rose Evard, Jacquelyn J. Rickson, Quinn White, Lynnette Leidy Sievert

Exercise and Sport Studies: Faculty Publications

Importance and Objective: Hot flashes (HFs) are a prevalent feature of menopause. Hot flashes can be bothersome and affect quality of life. However, HFs have also been associated with the risk for cardiovascular disease. Therefore, providing current evidence on the effect of therapies to reduce HFs can help patients and providers with decision making. This review provides details on the scientific evidence to date related to the effect of physical activity (PA) and exercise to alter the HF experience in women

Methods: The PubMed database was searched between June 2020 and June 2022 for currently available evidence regarding the relation …

Efficacy Of Covid-19 Public Health Measures In Philadelphia, New York City, Baltimore, And Chicago, Brian Goldstein, Willie H. Oglesby

College of Population Health Faculty Papers

Introduction: From the early days of the pandemic, US cities have implemented a variety of public health measures to reduce the spread of COVID-19. This study investigates which policies were most effective in reducing cases of COVID-19 in four major cities: Philadelphia, New York City, Baltimore, and Chicago.

Methods: Through a cross-comparative analysis, we developed a timeline that tracked the implementation of a range of public health measures along with changes in COVID-19 cases, hospitalizations, and deaths. Data were collected from publicly available government sites and from press releases.

Results: The results from the stay-at-home orders illustrate the delayed impact …

Diversity Still Matters: School-Level Racial Diversity, Poverty And Performance Of New York City Public Schools, Byunghwa Kim

Dissertations, Theses, and Capstone Projects

During the last few decades, schools in New York City (NYC) have experienced great demographic changes due to the massive influx of various ethnic and racial groups. Although the race and ethnicity makeup of NYC is 42% white, 29% Hispanic or Latino, 24% Black or African American and 14% Asian, 74% of Black and Hispanic students attend a school with less than 10 percent white students, while 34% of white students attend a school with more than half white peers. Also, more than 60% of Hispanic and Black students are attending schools where more than 75% of peer students experience …

Engineered Plga Nanofibers For Drug Delivery, Andrew Mancuso

Dissertations, Theses, and Capstone Projects

Poly-lactic-co-glycolic acid (PLGA) polymers are rapidly gaining momentum as a platform for next-generation drug delivery systems due to their ease and low cost of synthesis, favorable biocompatibility and biodegradability, and lack of toxicity. In particular, the application of drug-loaded PLGA nanofibers directly to a target tissue may represent a promising alternative to traditional routes of drug administration (e.g., oral, injectable) as they offer the potential to greatly improve bioavailability, increase efficacy, and reduce off-target toxicity. Furthermore, the use of such a system may potentially allow for greater flexibility in clinical drug development, by enabling the use of compounds which have …

Factors Associated With Technology Adoption By Community-Dwelling Older Adults During The Covid-19 Pandemic, Elizabeth A. Sutton

Dissertations, Theses, and Capstone Projects

The COVID-19 pandemic brought to the forefront the disparity between older and younger Americans in the utilization of information and communication technologies (ICT) when measures such as the COVID vaccine rollout were dependent on technology use. Technology adoption has implications for overall health and the continuation of disparities in technology adoption is associated with poor aging outcomes. The aim of this study was to understand factors associated with technology adoption by community-dwelling older adults during the COVID-19 pandemic. A nationally representative sample of 2,954 community-dwelling older adults who completed the National Health and Aging Trends Study (NHATS) COVID-19 Questionnaire was …

Examining Factors Related To Tobacco Treatment Engagement Among Tobacco Dependent Black/African American; Hispanic/Latino Cancer Patients: An Analysis Of Memorial Sloan Kettering Cancer Center’S Tobacco Treatment Program, Gleneara E. Bates-Pappas

Dissertations, Theses, and Capstone Projects

Among patients diagnosed with cancer, persistent tobacco use is associated with adverse clinical outcomes such as worse treatment side effects, decreased effectiveness of cancer treatment (chemotherapy, radiotherapy, and surgery), all increasing risk of recurrence, second primary cancers, and poor survival. Despite the clinical importance of tobacco cessation in the context of high quality cancer care, engaging Black/African American and Hispanic/Latino cancer patients in tobacco treatment programs can be challenging. Prior studies with the general adult population demonstrate that Black/African American and Hispanic/Latino smokers are referred to and accept tobacco cessation treatment at lower rates compared to non-Hispanic White smokers. This …

Antimatters: The Curious Case Of Confederate Monuments, Jeremiah Chin

Articles

Confederate monuments sit at a crossroads of speech frameworks as contested government speech, as concrete edifices of hate speech, and as key protest sites. The interplay of state law and speech doctrines in states like Alabama and Florida has cemented monuments as physical representations of government speech that municipal governments cannot speak on. To understand the confounding ways that doctrinal principles take on inverse implications, this Article draws on the concept of antimatter in physics—matter that has the same mass and properties of ordinary matter but with the opposite charge—to analyze doctrinal intersections of constitutional law that are made to …

Ending The Hiv Epidemic: Identifying Barriers And Facilitators To Implement Molecular Hiv Surveillance To Develop Real-Time Cluster Detection And Response Interventions For Local Communities, Moctezuma Garcia, Samantha Devlin, Jared Kerman, Kayo Fujimoto, Lisa R. Hirschhorn, Gregory Phillips, John Schneider, Moira C. Mcnulty

Faculty Research, Scholarly, and Creative Activity

The rapid implementation of molecular HIV surveillance (MHS) has resulted in significant challenges for local health departments to develop real-time cluster detection and response (CDR) interventions for priority populations impacted by HIV. This study is among the first to explore professionals’ strategies to implement MHS and develop CDR interventions in real-world public health settings. Methods: Semi-structured qualitative interviews were completed by 21 public health stakeholders in the United States’ southern and midwestern regions throughout 2020–2022 to identify themes related to the implementation and development of MHS and CDR. Results for the thematic analysis revealed (1) strengths and limitations in utilizing …

Introduction To Sharon Dunwoody Memorial Issue, Robert J. Griffin, Susanna Priest, Lee A. Kahlor

College of Communication Faculty Research and Publications

This introduction to our February 2023 issue is intended to provide context for the issue content, which presents multiple examples of the ongoing influence of the work of the late Sharon Dunwoody. Contemporary research articles, commentary pieces, and the introduction itself reflect Sharon’s deep influence on science communication and science communication researchers and their work.

A Call For Help: Tailored Training For Suicide Prevention In Libraries, Marina Hand, Lacey Rogers

Criss Library Faculty Proceedings & Presentations

In 2018, 48,000 deaths by suicide were reported out of 1.4 million attempts in the United States. Those most at risk are Native Americans, Veterans, people living in predominantly rural areas, and LBGTQ+ Youth. Of these at-risk demographics men are 3.7% more likely to commit suicide than women. In the state of Nebraska alone suicide occurs in 12.5 per 100,000 people, keeping in line with the national average of that year. Within the last year, the number of staff reporting alarming phone calls from distressed patrons has grown. The pandemic has exacerbated mental health issues among the population, which lends …

Examining The Effect Of A Substituted Carbamate Positive Allosteric Modulator On (Alpha4)3(Beta2)2 And (Alpha4)2(Beta2)3 Nicotinic Acetylcholine Receptors, Josue Gaona, Musharaf Mohiuddin, Ayman K. Hamouda

School of Medicine Student Publications and Presentations

The α4β2 nicotinic acetylcholine receptors (nAChR) are the most abundant nAChR subtypes in the brain and exist in two distinct isoforms: (α4)2(β2)3 nAChR, the high sensitivity (HS) isoform, and (α4)3(β2)2 nAChR, the low sensitivity (LS) isoform. Given the pathophysiological and pharmacological importance of these brain receptors, there are ongoing efforts to develop pharmacophores that selectively potentiate α4β2 nAChRs (positive allosteric modulators, PAMs). PAMs selective to the α4β2 nAChRs would be beneficial for neuropsychiatric conditions such as nicotine addiction and Alzheimer’s disease. A chemical synthesis and high throughput screens at Amgen laboratories have identified a series of compounds that preferentially potentiate …

A Single Bout Of Breast Milk Expression Does Not Increase Resting Metabolic Rate, Leryn J. Reynolds, Kayla R. Powell, Taskina Akhter, Hannah M. Twiddy, Patrick B. Wilson

Human Movement Studies & Special Education Faculty Publications

Introduction: Breastfeeding women have elevated resting metabolic rate (RMR); however, whether a single bout of lactation increases RMR is unknown. This study aimed to determine if a single bout of lactation acutely increased RMR.

Methods: Twenty-two lactating women (age: 31 ± 0.9 year, body mass index: 27.3 ± 1.2 kg/m²) were recruited. RMR was assessed at baseline and at 1- and 2-h following breast milk expression.

Results: RMR was unchanged in lactating women following a single bout of lactation (baseline: 1437 ± 39; 1 h: 1425 ± 37 2 h: 1440 ± 31 kcal/day) (p > .05). RMR was …

Association Of Endovascular Thrombectomy Vs Medical Management With Functional And Safety Outcomes In Patients Treated Beyond 24 Hours Of Last Known Well, Amrou Sarraj, Timothy J Kleinig, Ameer E Hassan, Pere Cardona Portela, Santiago Ortega-Gutierrez, Michael G Abraham, Nathan W Manning, James E Siegler, Nitin Goyal, Laith Maali, Spiros Blackburn, Teddy Y Wu, Jordi Blasco, Arturu Renú, Navdeep S Sangha, Juan F Arenillas, Margy E Mccullough-Hicks, Adam Wallace, Daniel Gibson, Deep K Pujara, Faris Shaker, Mercedes De Lera Alfonso, Marta Olivé-Gadea, Mudassir Farooqui, Juan S Vivanco Suarez, Zachary Iezzi, Jane Khalife, Colleen G Lechtenberg, Syed K Qadri, Rami B Moussa, Mohammad A Abdulrazzak, Tareq S Almaghrabi, Osman Mir, James Beharry, Balaji Krishnaiah, Megan Miller, Najwa Khalil, Gagan J Sharma, Aristeidis H Katsanos, Ali Fadhil, Kelsey R Duncan, Yin Hu, Sheryl B Martin-Schild, Georgios K Tsivgoulis, Dennis Cordato, Anthony Furlan, Leonid Churilov, Peter J Mitchell, Adam S Arthur, Mark W Parsons, James C Grotta, Clark W Sitton, Marc Ribo, Gregory W Albers, Bruce C V Campbell

Faculty, Staff and Student Publications

IMPORTANCE: The role of endovascular thrombectomy is uncertain for patients presenting beyond 24 hours of the time they were last known well.

OBJECTIVE: To evaluate functional and safety outcomes for endovascular thrombectomy (EVT) vs medical management in patients with large-vessel occlusion beyond 24 hours of last known well.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective observational cohort study enrolled patients between July 2012 and December 2021 at 17 centers across the United States, Spain, Australia, and New Zealand. Eligible patients had occlusions in the internal carotid artery or middle cerebral artery (M1 or M2 segment) and were treated with EVT or …

Network Analysis Examining Intrahospital Traffic Of Patients With Traumatic Hip Fracture, Elizabeth A. Secor, David Hamilton, Cecile D'Huyvetter, Kristin Salottolo, David Bar-Or

GME Publications

Introduction: Increased intrahospital traffic (IHT) is associated with adverse events and infections in hospitalized patients. Network science has been used to study patient flow in hospitals but not specifically for patients with traumatic injuries.

Methods: This retrospective analysis included 103 patients with traumatic hip fractures admitted to a level I trauma center between April 2021 and September 2021. Associations with IHTs (moves within the hospital) were analyzed using R (4.1.2) as a weighted directed graph.

Results: The median (interquartile range) number of moves was 8 (7–9). The network consisted of 16 distinct units and showed mild disassortativity (−0.35), similar to …

Adjuvant 5-Fluorouracil/Leucovorin, Capecitabine, And Oxaliplatin-Related Regimens For Stage Ii/Iii Colon Cancer Patients 66 Years Or Older, Emily Jones, Zhigang Duan, Thinh T Nguyen, Sharon H Giordano, Hui Zhao

Faculty, Staff and Student Publications

Adjuvant chemotherapy of leucovorin-modulated 5-fluorouracil (5-FU/LV), capecitabine, and adding oxaliplatin to 5-FU/LV or capecitabine (FLOX/OX) have been standard regimens for high-risk stage II or III colon cancer (CC). We aimed to evaluate their patterns of use, association with survival, and rate of emergency room visit (ER) or hospitalization during the treatment period. High-risk stage II or III patients aged >65 years diagnosed between 2007 and 2015, underwent colectomy, and received any of these three regimens were selected from SEER and Texas Cancer Registry (TC) linked with Medicare data. Chi-square test, Kaplan-Meier survival curves, Cox regression, and logistic regression were used …

First- Or Second-Trimester Sars-Cov-2 Infection And Subsequent Pregnancy Outcomes, Brenna L Hughes, Grecio J Sandoval, Torri D Metz, Rebecca G Clifton, William A Grobman, George R Saade, Tracy A Manuck, Monica Longo, Amber Sowles, Kelly Clark, Hyagriv N Simhan, Dwight J Rouse, Hector Mendez-Figueroa, Cynthia Gyamfi-Bannerman, Jennifer Bailit, Maged M Costantine, Harish M Sehdev, Alan T N Tita, George A Macones

Faculty, Staff and Student Publications

BACKGROUND: SARS-CoV-2 infection during pregnancy is associated with adverse pregnancy outcomes, including fetal death and preterm birth. It is not known whether that risk occurs only during the time of acute infection or whether the risk persists later in pregnancy.

OBJECTIVE: This study aimed to evaluate whether the risk of SARS-CoV-2 infection during pregnancy persists after an acute maternal illness.

STUDY DESIGN: A retrospective cohort study of pregnant patients with and without SARS-CoV-2 infection delivering at 17 hospitals in the United States between March 2020 and December 2020. Patients experiencing a SARS-CoV-2-positive test at or before 28 weeks of gestation …

Superficial Low-Grade Fibromyxoid Sarcoma, Shira Ronen, Jennifer S Ko, Brian P Rubin, Scott E Kilpatrick, Wei-Lien Wang, Alexander J Lazar, John R Goldblum, Steven D Billings

Faculty, Staff and Student Publications

Background: Low-grade fibromyxoid sarcoma (LGFMS) typically involves deep soft tissue (beneath the fascia) of the proximal extremities and trunk. Long-term follow-up has shown a high rate of local recurrence, metastasis, and death. To the best of our knowledge, there is only one previous large series focusing on superficial LGFMS suggesting superficial tumors are disproportionately more common in children and may have a better prognosis. Our study's primary goals are to confirm these findings and increase general awareness that LGFMS may arise in superficial soft tissue.

Methods: We retrieved our cases of superficial LGFMS diagnosed between 2008 and 2020. Available slides …

Cotargeting Of Btk And Malt1 Overcomes Resistance To Btk Inhibitors In Mantle Cell Lymphoma, Vivian Changying Jiang, Yang Liu, Junwei Lian, Shengjian Huang, Alexa Jordan, Qingsong Cai, Ruitao Lin, Fangfang Yan, Joseph Mcintosh, Yijing Li, Yuxuan Che, Zhihong Chen, Jovanny Vargas, Maria Badillo, John Nelson Bigcal, Heng-Huan Lee, Wei Wang, Yixin Yao, Lei Nie, Christopher R Flowers, Michael Wang

Faculty, Staff and Student Publications

Bruton's tyrosine kinase (BTK) is a proven target in mantle cell lymphoma (MCL), an aggressive subtype of non-Hodgkin lymphoma. However, resistance to BTK inhibitors is a major clinical challenge. We here report that MALT1 is one of the top overexpressed genes in ibrutinib-resistant MCL cells, while expression of CARD11, which is upstream of MALT1, is decreased. MALT1 genetic knockout or inhibition produced dramatic defects in MCL cell growth regardless of ibrutinib sensitivity. Conversely, CARD11-knockout cells showed antitumor effects only in ibrutinib-sensitive cells, suggesting that MALT1 overexpression could drive ibrutinib resistance via bypassing BTK/CARD11 signaling. Additionally, BTK knockdown and MALT1 knockout …