Digital Commons Network^™

Baseball Media Guide 2023, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Love And Information, Caryl Churchill

Theatre and Performance Studies Programs

In a world that is increasingly virtual, how do we traverse the devastating gap between our longing for love and our addictive need for information? In this fascinating kaleidoscope of 57 short plays, more than 100 characters try to find true human connection and make sense of what they know--and don't know. A mesmerizing and unpredictable play by one of the world's most groundbreaking playwrights, Caryl Churchill. Directed by Emily Kitchens.

Equity Fund Monthly Report, February 2023, Bryant University, Archway Investment Fund

Archway Investment Fund

No abstract provided.

Gw Ophthalmology On-Call: 02/2023, Yusuf Bade, Meredith Wells, Sasha Narain, Jacob Diaz

GW Ophthalmology On-Call

No abstract provided.

Canine As A Comparative And Translational Model For Human Mammary Tumor., Jee Young Kwon, Nicholas Moskwa, Wonyoung Kang, Timothy M Fan, Charles Lee

Faculty Research 2023

Despite the advances in research and treatment of human breast cancer, its incidence rate continues to increase by 0.5% per year, and the discovery of novel therapeutic strategies for specific subtypes of human breast cancer remains challenging. Traditional laboratory mouse models have contributed tremendously to human breast cancer research. However, mice do not develop tumors spontaneously; consequently, genetically engineered mouse models or patient-derived xenograft models are often relied upon for more sophisticated human breast cancer studies. Since human breast cancer develops spontaneously, there is a need for alternative, yet complementary, models that can better recapitulate the features of human breast …

An Integrative Approach For Exploring The Nature Of Fibroepithelial Neoplasms., Jihui Yun, Woohang Heo, Eun-Shin Lee, Deukchae Na, Wonyoung Kang, Jinjoo Kang, Jeesoo Chae, Dakyung Lee, Woochan Lee, Jinha Hwang, Tae-Kyung Yoo, Bok Sil Hong, Hye-Youn Son, Dong-Young Noh, Charles Lee, Hyeong-Gon Moon, Jong-Il Kim

Faculty Research 2023

BACKGROUND: Malignant phyllodes tumour (MPT) is a rare breast malignancy with epithelial and mesenchymal features. Currently, there are no appropriate research models or effective targeted therapeutic approaches for MPT.

METHODS: We collected fresh frozen tissues from nine patients with MPT and performed whole-exome and RNA sequencing. Additionally, we established patient-derived xenograft (PDX) models from patients with MPT and tested the efficacy of targeting dysregulated pathways in MPT using the PDX model from one MPT.

RESULTS: MPT has unique molecular characteristics when compared to breast cancers of epithelial origin and can be classified into two groups. The PDX model derived from …

Bmp10 Functions Independently From Bmp9 For The Development Of A Proper Arteriovenous Network., Hyunwoo Choi, Bo-Gyeong Kim, Yong Hwan Kim, Se-Jin Lee, Young Jae Lee, S Paul Oh

Faculty Research 2023

Hereditary hemorrhagic telangiectasia (HHT) is a genetic vascular disorder characterized by the presence of arteriovenous malformation (AVM) in multiple organs. HHT is caused by mutations in genes encoding major constituents for transforming growth factor-β (TGF-β) family signaling: endoglin (ENG), activin receptor-like kinase 1 (ALK1), and SMAD4. The identity of physiological ligands for this ENG-ALK1 signaling pertinent to AVM formation has yet to be clearly determined. To investigate whether bone morphogenetic protein 9 (BMP9), BMP10, or both are physiological ligands of ENG-ALK1 signaling involved in arteriovenous network formation, we generated a novel Bmp10 conditional knockout mouse strain. We examined whether global …

A Multicenter Study Of Clinical Impact Of Variant Of Uncertain Significance Reclassification In Breast, Ovarian And Colorectal Cancer Susceptibility Genes., Sukh Makhnoon, Brooke Levin, Megan Ensinger, Kristin Mattie, Robert J Volk, Zhongming Zhao, Tito Mendoza, Sanjay Shete, Laila Samiian, Generosa Grana, Andrew Grainger, Banu Arun, Brian H Shirts, Susan K Peterson

Oncology Articles

BACKGROUND: Clinical interpretation of genetic test results is complicated by variants of uncertain significance (VUS) that have an unknown impact on health but can be clarified through reclassification. There is little empirical evidence regarding VUS reclassification in oncology care settings, including the prevalence and outcomes of reclassification, and racial/ethnic differences.

METHODS: This was a retrospective analysis of persons with and without a personal history of cancer carrying VUS (with or without an accompanying pathogenic or likely pathogenic [P/LP] variant) in breast, ovarian, and colorectal cancer predisposition genes seen at four cancer care settings (in Texas, Florida, Ohio, and New Jersey) …

Considerations For Marijuana Legalization, Joe Ainslie

Master of Arts in Criminal Justice Leadership

Marijuana legalization began approximately 29 years ago but legalization has only gained momentum in recent years. Most states in the US have enacted laws allowing for medical marijuana or recreational marijuana use. These laws have all been enacted with the past 20 years and highlighted the complicated issue of legalization of once heavily controlled substances. Minnesota is now beginning the process of legalizing recreational use of marijuana and introduced legislation. Legalization has brought with it public health and safety concerns as well as ethical dilemmas. The specific concerns about an increase in driving while intoxicated/impaired (DWI), crashes, heightened criminality, and …

Thriving Pastors Cohort: Expanding Capacity For Lifelong Ministry, Michael Spivey

Doctor of Ministry

Assemblies of God pastors can expand their capacity for lifelong thriving by avoiding or recovering from ministry fatigue or burnout. The key insights that emerged from my research are as such: 1) Ministers are a vulnerable and largely self-isolating group who need a mechanism for spiritual growth and companionship. 2) There is already good work being accomplished in this arena, but pastoral thriving can be further nuanced and presented in a non-threatening and life-giving way. 3) There is not a singular way to accomplish the task of assisting ministers to engage in ongoing spiritual advancement. The cohort is but one …

Sol's Porch: Seeking A More Unified Church In A Divisive Culture, Kevin Miller

Doctor of Ministry

In this project portfolio, I will address the following NPO: The fragmented church has countless interpretations of truth caused by tribal fear, which has created ongoing divisions and a longing for control. If unified in Jesus, we could see radical inclusivity in future generations. The key finding in my research revealed the unifying power of Jesus being the ultimate authority of our faith, Bible readings, and Christian practice. I have seen the prevalent church fragments in America and in my current context as a missionary in Toulouse, France. I believe the power of story and metaphor can play a part …

Sanctified; A Formational Hermeneutic Of The Sanctuary In Seven Reflections, Miguel Mendez

Doctor of Ministry

The initial impetus for the project was to produce a hermeneutical approach that would privilege diversity within the Adventist church. The NPO as initially envisioned was directed to church leadership; the foci however shifted toward a local congregation as it dealt with denominational pressure and internal conflict. The notion of a heavenly Sanctuary that serves as a replica of the Earthly tabernacle looms large in Adventism, it remains foundational to the denomination’s understanding of eschatology, ecclesiology, and missiology. Adventism espouses the belief that Jesus has been ministering in this heavenly Sanctuary since October 22, 1844. This unique understanding of Christ’s …

Place Informs Posture: Developing A Model Of Spatial Lectio Divina For Under-Resourced African Christian Leaders, Chris Kamalski

Doctor of Ministry

NPO DESCRIPTION: How can a small, covenanted, safe community of African Christian leaders grow into the most transformative environment for a person to be formed and empowered holistically?

KEY RESEARCH INSIGHTS: 1. ‘Place informs posture.’ A Christian leader’s socio-cultural position frames their perspective on – and opportunities to receive – ongoing spiritual formation and leadership development. To empower under-resourced Christian leaders ministering in an environment of survival, formation must grow from acknowledging this reality. 2. ‘Leaders thrive deeply in safe cohort communities of their peers.’ A ‘third’ space where leaders can grow in community without fear of becoming spiritually unhealthy …

Built To Last: An In-Depth Look At The Multisite Church And Ministry Succession, Scott R. Jones

Doctor of Ministry

The multisite church model is a movement that, by all indications, is here to stay. According to Portable Church Industries, there are only twelve single-campus churches listed among the top 100 largest churches in the United States. If multi-site churches were a Protestant denomination, they’d be the fourth largest. 1 The NPO addressed is: Multisite churches are predominantly first generation with personality centric leadership, needing intentionality for sustainability and succession. I serve as lead pastor of Grace Church – a non-denominational church with four campuses in the Houston area. I am in my 28th year of tenure. We transitioned to …

Mteule: A Program Of Healing And Spiritual Growth, Kathy Ham

Doctor of Ministry

Mteule is a one-year program of Spiritual Formation designed for the camp mentors of Angaza Discovery Camp and other staff members of Missions of Hope International (MOHI). Mteule means ‘set apart’ in Swahili. Mteule was developed to address the following need, problem, or opportunity: Camp mentors and other staff from the Mathare Valley come with their own experiences of trauma and can be lacking the capacity to maturely minister to traumatized children. MOHI is a Christian non-profit providing spiritual development, education, physical well-being, and sustainability training/micro-finance opportunities to those living in abject poverty in Kenya. MOHI currently has 31 Hope …

Novel Signposts On The Road From Natural Sources To Pharmaceutical Applications: A Combinative Approach Between Lc-Dad-Ms And Offline Lc-Nmr For The Biochemical Characterization Of Two Hypericum Species (H. Montbretii And H. Origanifolium), Stefania Sut, Stefano Dall'acqua, Gokhan Zengin, Ismail Senkardes, Abdullahi Ibrahim Uba, Abdelhakim Bouyahya, Abdurrahman Aktumsek

College of Science & Mathematics Departmental Research

The members of the genus Hypericum have great potential to develop functional uses in nutraceutical and pharmaceutical applications. With this in mind, we aimed to determine the chemical profiling and biological properties of different extracts (ethyl acetate, methanol and water) from two Hypericum species (H. montbretii and H. origanifolium). We combined two approaches (LC-DAD-MS and LC-NMR) to identify and quantify chemical compounds of the extracts. Antioxidant properties (free radical quenching, reducing power and metal chelating) and enzyme inhibitory effects (cholinesterase, tyrosinase, amylase and glucosidase) were determined as biological properties. The tested extracts were rich in caffeic acid derivatives and flavonoids, …

Kendrick Langley V. Ups Inc

2023 Decisions

USDC for the District of New Jersey

Pharmacy Matters - February 2023, University Of Mississippi. School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: "Center’s Role Critical in Quality and Safety of Supplements, Cosmetics," "First MacEachern Scholarship Recipients Express Gratitude," "Pharmacy School Hosts EDI Institute, Furthers School Diversity Efforts," "UM Pharmacy Gathers at State Capitol," "Student Elected Academy of Student Pharmacists Delegate"

Animal Welfare - Environment - Sustainable Development Nexus: Scoping Study, Janice H. Cox

Nexus – UNEP – Animal Welfare, Environment, Sustainable Development

A detailed report on the links between animal welfare, environmental health and global sustainability. Issues discussed include climate change, biodiversity, pollution and waste management, one health, sustainable development and just transitions.

Prevalence Of Post-Traumatic Stress Disorder Among Peshmargas, Whom Fought Against Isis Warin Kurdistan Region Borders, Shireen J. Mohammed, Hoshyar A. Ahmed

Polytechnic Journal

Psychological disturbanceis one of the most significant feature amongst individuals who are served military tasks. This study presentedthe Post Traumatic Disorder (PTSD) among the peshmargas(Kurdish military personnel) who joined in ISIS war. The aim of this study is todetermine the prevalence of post-traumatic stress disorder among peshmargas returning from war and to identify the associated factors of PTSD among the study sample.

Biocontrol Activities Of Olive Endophytic Bacteria Isolates Against Pseudomonas Savastanoi, Avin Omer Ali, Tavga Sulaiman Rashid

Polytechnic Journal

Background and objectives: Olive knot disease caused by the phytopathogenic bacterium Pseudomonas savastanoi affects olive cultivation in both quality and quantity. Endophytic bacteria are candidates for biocontrol agents according to previous research. Methods: In this study we collected samples (leaves and galls) randomly for pathogen and endophytic bacteria isolation from the different olive growing areas around Erbil including (Qucha Blbas, Grdasor, Sami Abdulrahman Park, and College of Agricultural Engineering Sciences) on June - October 2021. Results: Forty-six isolates of endophytic bacteria were obtained and tested against P. savastanoi. The result indicated that five isolates showed growth inhibition of the pathogen …

Knowledge Protocol Of Direct And Indirect Veneers Among Dental Practitioners - A Case Study, Sazan Manaf Azeez, Bassam Kareem Amin, Noor Kaylan Hamid, Ali Ali Saber

Polytechnic Journal

Background and objectives: Dental veneers are constructed from different materials such as porcelain, pressed ceramic, processed composite, or directly applied composite. The purpose of this study was to ascertain the preferred dental materials for veneers and the knowledge about its procedures by dentists in the Kurdistan region/Erbil city Methods: To assess general dentists' knowledge and practical use of direct and indirect veneers, a cross-sectional survey was undertaken in March 2022 among all general dentists and different dental specialties in Erbil city. The questionnaire was composed of 16 questions and was organized into knowledge, attitude, and practice sections. Google forms were …

Analysis Of Potential Application Of California Environmental Quality Act (Ceqa) Exemptions To Investor-Owned Utility Wildfire Mitigation Plans To Accelerate Fire Prevention And Mitigation Efforts, Anastasia Telesetsky, William Siembieda

WUI Fire Institute

Wildfire poses an existential threat for California. Five of the six largest wildfires in California’s history occurred in 2020 and 2021 including the first fire to ever impact over 1 million acres. Between 2014-2018, the California Department of Forestry and Fire Protection (CAL FIRE) identified electrical power generation as igniting more fires than lightning strikes. In response to electrical utility assets igniting wildfires, the State of California has mandated that investor-owned utilities (IOU) develop Wildfire Mitigation Plans (WMP) that include a spectrum of mitigation and prevention efforts including undergrounding of utilities, hardening of electrical assets (e.g., converting wooden poles to …

2023-02-01_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Persons In Crisis: Law Enforcement's Response To Mental Health Calls, Sean Farnham

Master of Arts in Criminal Justice Leadership

This research paper provided insight and the history surrounding the mental health epidemic in the United States, the burden that is placed upon the law enforcement profession and offered strategies to address to the problem. The paper offered suggestions on how the various strategies can be implemented within a law enforcement organization, considering funding, personnel, and policy and procedure. The paper offered research surrounding several response methods for law enforcement to utilize when responding to calls involving mental health factors, the ethics concerns surrounding the response methods, and offered suggestions on how organizations can begin to implement new response methods …

Peaks Island Star : February 2023, Vol. 43, Issue 2, Service Agencies Of The Island

Peaks Island Star, 2023

The Peaks Island Star is the newsletter of the island's service agencies and other community news.

Neurobehavioral Deficits Of Mice Expressing A Low Level Of G127v Mutant Frataxin., Daniel Fil, Robbie L Conley, Aamir Zuberi, Cathleen Lutz, Terry Gemelli, Marek Napierala, Jill S Napierala

Faculty Research 2023

Friedreich’s ataxia (FRDA) is a neurodegenerative disease caused by reduced expression of the mitochondrial protein frataxin (FXN). Most FRDA patients are homozygous for large expansions of GAA repeats in intron 1 of FXN, while some are compound heterozygotes with an expanded GAA tract in one allele and a missense or nonsense mutation in the other. A missense mutation, changing a glycine to valine at position 130 (G130V), is prevalent among the clinical variants. We and others have demonstrated that levels of mature FXN protein in FRDA G130V samples are reduced below those detected in samples harboring homozygous repeat expansions. Little …

Young Professionals, Lehigh Valley Health Network

Young Professionals

No abstract provided.

Nonprofit Spotlight 1: The Hydrous

Journal of Nonprofit Innovation

The mission of the Hydrous is to create “open access oceans” so that all people may explore, understand, and engage with marine environments, which are severely threatened by climate change and human impacts.

Ileap: An Intercultural Leadership Pilgrimage For Young Adults (Age 18-24), Elmarie Parker

Doctor of Leadership

The opportunity addressed in this research is to create an effective leadership capacity-building experience equipping young adults (18-24 years old) to practice justice, equity, reconciliation, and perseverance while positively impacting society in Lebanon and Oregon. iLEAP: An Intercultural Leadership Pilgrimage for Young Adults, is the result. My research has revealed that young adults want a learning environment that supports the cultivation of positive self-identity, meaningful connection with others, and agency. They want to develop cross-cultural friendships and collaborations and want to be equipped for effectively working with difference. Additionally, they want to cultivate visioning skills that lead to discerning and …