Digital Commons Network^™

Various Unh Departments Affected By Shifting Mental Health Conversation, Victoria Fluet

Digital Edition

An independent student produced newspaper from the University of New Hampshire.

With Liberty And Justice For The Wealthy: The Criminalization Of The American Poor, Ashlyn Dickmeyer

Honors Program: Senior Projects (Public)

The last phrase of the Pledge of Allegiance states “with liberty and justice for all”. However, not everyone has access to this liberty and justice. Liberty and justice can be bought in this country for a price, and those who can’t afford to pay it are often left in the hands of those who can. One of the most prominent ways to see this is by analyzing the criminal justice system. Despite clauses in the Fourteenth Amendment and court cases like Gideon v. Wainwright (1963) establishing and upholding that the poor are entitled to equal treatment within the criminal justice …

A New, Extremely Sensitive, Turn-Off Optical Sensor Utilizing Schiff Base For Fast Detection Of Cu(Ii), Lotfi M Aroua, Reham Ali, Abuzar E A E Albadri, Sabri Messaoudi, Fahad M Alminderej, Sayed M Saleh

Faculty, Staff and Student Publications

Throughout this research, a unique optical sensor for detecting one of the most dangerous heavy metal ions, Cu(II), was designed and developed. The (4-mercaptophenyl) iminomethylphenyl naphthalenyl carbamate (MNC) sensor probe was effectively prepared. The Schiff base of the sensor shows a "turn-off" state with excellent sensitivity to Cu(II) ions. This innovative fluorescent chemosensor possesses distinctive optical features with a substantial Stocks shift (about 114 nm). In addition, MNC has remarkable selectivity for Cu(II) relative to other cations. Density functional theory (DFT) and the time-dependent DFT (TDDFT) theoretical calculations were performed to examine Cu(II) chelation structures and associated electronic properties in …

Lindenwood Digest, March 8, 2023, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Adherence To Physical Rehabilitation Delivered Via Tele-Rehabilitation For People With Multiple Sclerosis: A Scoping Review Protocol, Geraldine Goldsmith, Jessica C. Bollen, Victoria E. Salmon, Jennifer A. Freeman, Sarah G. Dean

School of Health Professions

IntroductionUsing tele-rehabilitation methods to deliver exercise, physical activity (PA) and behaviour change interventions for people with multiple sclerosis (pwMS) has increased in recent years, especially since the SARS-CoV-2 pandemic. This scoping review aims to provide an overview of the literature regarding adherence to therapeutic exercise and PA delivered via tele-rehabilitation for pwMS.Methods and analysisFrameworks described by Arksey and O’Malley and Levacet alunderpin the methods. The following databases will be searched from 1998 to the present: Medline (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Health Management Information Consortium Database, ProQuest Dissertations and Theses Global, Pedro, Cochrane Central Register of Controlled Trials, US National …

Examination Of Sleep In Relation To Dietary And Lifestyle Behaviors During Ramadan: A Multi-National Study Using Structural Equation Modeling Among 24,500 Adults Amid Covid-19, Moien A. B. Khan, Ahmed S. Bahammam, Asma Amanatullah, Khaled Obaideen, Teresa Arora, Habiba Ali, Leila Cheikh Ismail, Dana N. Abdelrahim, Mohammed Al-Houqani, Kholoud Allaham, Rand Abdalrazeq, Wahid Sharif Aloweiwi, Somayea Sultana Mim, Ammar Mektebi, Sohrab Amiri, Sahabi Kabir Sulaiman, Syed Fahad Javaid, Mohammad Delwer Hossain Hawlader, Fatimah Isma’Il Tsiga-Ahmed, Iffat Elbarazi, Saskiyanto Manggabarani, Gamechu Atomsa Hunde, Sabrina Chelli, Mitra Sotoudeh, Moezalislam Ezzat Faris, Ramadan Intermittent Fasting Collaborators, Abasi-Okot Akpan Udoyen, Abdelrhman Muwafaq Janem, Abdullah Taha Zayed, Adriana Johny Skafi

All Works

Background Of around 2 billion Muslims worldwide, approximately 1.5 billion observe Ramadan fasting (RF) month. Those that observe RF have diverse cultural, ethnic, social, and economic backgrounds and are distributed over a wide geographical area. Sleep is known to be significantly altered during the month of Ramadan, which has a profound impact on human health. Moreover, sleep is closely connected to dietary and lifestyle behaviors. Methods This cross-sectional study collected data using a structured, self-administered electronic questionnaire that was translated into 13 languages and disseminated to Muslim populations across 27 countries. The questionnaire assessed dietary and lifestyle factors as independent …

Lead-Free Perovskite Homojunction-Based Htm-Free Perovskite Solar Cells: Theoretical And Experimental Viewpoints, Sajid Sajid, Salem Alzahmi, Imen Ben Salem, Jongee Park, Ihab M. Obaidat

All Works

Simplifying the design of lead-free perovskite solar cells (PSCs) has drawn a lot of interest due to their low manufacturing cost and relative non-toxic nature. Focus has been placed mostly on reducing the toxic lead element and eliminating the requirement for expensive hole transport materials (HTMs). However, in terms of power conversion efficiency (PCE), the PSCs using all charge transport materials surpass the environmentally beneficial HTM-free PSCs. The low PCEs of the lead-free HTM-free PSCs could be linked to poorer hole transport and extraction as well as lower light harvesting. In this context, a lead-free perovskite homojunction-based HTM-free PSC was …

Office Of Research, Economic Engagement And Outreach Update, March 8, 2023, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Factors Affecting Variability In Vestibulo-Ocular Reflex Gain In The Video Head Impulse Test In Individuals Without Vestibulopathy: A Systematic Review Of Literature, Laurel Elise Money-Nolan, Ashley G. Flagge

Ashley Flagge Publications

The purpose of this systematic review was to summarize and synthesize published evidence examining variations in vestibulo-ocular reflex (VOR) gain outcomes for the Video Head Impulse Test (vHIT) in healthy individuals without vestibulopathy in order to describe factors that may influence test outcomes. Computerized literature searches were performed from four search engines. The studies were selected based on relevant inclusion and exclusion criteria, and were required to examine VOR gain in healthy adults without vestibulopathy. The studies were screened using Covidence (Cochrane tool) and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement standards (PRISMA-2020). A total of …

Conjunctival And Lingual Mucosal Neuromas Without Multiple Endocrine Neoplasia Type 2b, Talia N. Shoshany, Christopher J. Rapuano, Tatyana Milman

Wills Eye Hospital Papers

Purpose: To report a patient with conjunctival and buccal neuromas and enlarged corneal nerves without Multiple Endocrine Neoplasia 2B (MEN2B).

Observations: A 28-year-old female presented with progressively enlarging bilateral limbal conjunctival growths. Slit lamp examination was notable for enlarged corneal nerves and well-circumscribed gelatinous subepithelial limbal nodules. Systemic examination revealed similar lesions on the tongue. Conjunctival biopsy demonstrated a mucosal neuroma. The patient underwent endocrine workup for MEN2B and genetic testing for the RET-proto oncogene mutations, all of which were negative.

Conclusions and Importance: The findings in our patient may be compatible with pure mucosal neuroma syndrome. The pattern of …

Evidence For A Causal Role For Escherichia Coli Strains Identified As Adherent-Invasive (Aiec) In Intestinal Inflammation, Hatem Kittana, Joao Carlos Gomes-Neto, Kari Heck, Anthony Juritsch, Jason Sughroue, Yibo Xian, Sara Mantz, Rafael R. Segura Muñoz, Liz Cody, Robert J. Schmaltz, Christopher L. Anderson, Rodney A. Moxley, Jesse M. Hostetter, Samodha C. Fernando, Jennifer Clarke, Stephen D. Kachman, Clayton E. Cressler, Andrew K. Benson, Jens Walter

Department of Nutrition and Health Sciences: Faculty Publications

Enrichment of adherent-invasive Escherichia coli (AIEC) has been consistently detected in subsets of inflammatory bowel disease (IBD) patients. Although some AIEC strains cause colitis in animal models, these studies did not systematically compare AIEC with non-AIEC strains, and causal links between AIEC and disease are still disputed. Specifically, it remains unclear whether AIEC shows enhanced pathogenicity compared to that of commensal E. coli found in the same ecological microhabitat and if the in vitro phenotypes used to classify strains as AIEC are pathologically relevant. Here, we utilized in vitro phenotyping and a murine model of intestinal inflammation to systematically compare …

Reduced Fire Severity Offers Near-Term Buffer To Climate-Driven Declines In Conifer Resilience Across The Western United States, Kimberley T. Davis, Marcos D. Robles, Kerry B. Kemp, Philip E. Higuera, Teresa Chapman, Kerry L. Metlen, Jamie L. Peeler, Kyle C. Rodman, Travis Woolley, Robert N. Addington, Brian J. Buma, Alina C. Cansler, Michael J. Case, Brandon M. Collins, Jonathan D. Coop, Solomon Z. Dobrowski, Nathan S. Gill, Collin Haffey, Lucas B. Harris, Brian J. Harvey, Ryan D. Haugo, Matthew D. Hurteau, Dominik Kulakowski, Caitlin E. Littlefield, Lisa A. Mccauley, Nicholas Povak, Kristen L. Shive, Edward Smith, Jens T. Stevens, Camille S. Stevens-Rumann, Alan H. Taylor, Alan J. Tepley, Derek J.N. Young, Robert A. Andrus, Mike A. Battaglia, Julia K. Berkey, Sebastian U. Busby, Amanda R. Carlson, Marin E. Chambers, Erich Kyle Dodson, Daniel Donato, William M. Downing, Paula J. Fornwalt, Joshua S. Halofsky, Ashley Hoffman, Andrés Holz, Jose M. Iniguez, Meg A. Krawchuk, Mark R. Krieder, Andrew J. Larson, Garrett W. Meigs, John Paul Roccaforte, Monica T. Rother, Hugh Safford, Michael Schaedel, Jason S. Sibold, Megan P. Singleton, Alexandra K. Urza, Kyra D. Clark-Wolf, Monica G. Turner

Geography

Increasing fire severity and warmer, drier postfire conditions are making forests in the western United States (West) vulnerable to ecological transformation. Yet, the relative importance of and interactions between these drivers of forest change remain unresolved, particularly over upcoming decades. Here, we assess how the interactive impacts of changing climate and wildfire activity influenced conifer regeneration after 334 wildfires, using a dataset of postfire conifer regeneration from 10,230 field plots. Our findings highlight declining regeneration capacity across the West over the past four decades for the eight dominant conifer species studied. Postfire regeneration is sensitive to high-severity fire, which limits …

Exploration Of Motivations For Adopting A Four-Day School Week Or Year Round Calendars: Evidence From Arkansas, Sarah C. Mckenzie, Josh B. Mcgee, Kate Barnes

Policy Briefs

This brief provides an overview of the motivations for Arkansas school districts adopting a four-day school week or year-round calendar. In addition to examining these motivations, this brief provides an overview of the districts adopting non-traditional calendars and policy recommendations for districts and communities considering changing calendars.

We Wanted To Do Something Innovative: Exploring Motivations Of Arkansas Districts Adopting Four-Day School Weeks Or Year-Round Calendars, Kate Barnes, Sarah C. Mckenzie

Arkansas Education Reports

Recent legislation has allowed Arkansas school districts increased flexibility to adopt a non-traditional calendar. Act 688 introduced four calendar options for districts: a traditional calendar, a four day calendar, a year-round calendar, and an alternate calendar based on the number of instructional hours.

During the 2022-23 school year, 33 school districts throughout the state adopted new calendars. The motivations behind why districts adopted new calendars were unclear. This report aims to identify the rationale behind why these districts moved away from the traditional calendar.

This report uses data gathered from interviews with twenty-three superintendents in districts that selected non-traditional calendars …

Ay 2022/2023 Sec Meeting Minutes, 2023-03-08, Faculty Senate

Faculty Senate Archives

No abstract provided.

Ay 2022/2023 Sec Agenda, 2023-03-08, Faculty Senate

Faculty Senate Archives

No abstract provided.

Assessing Public Reported Perceptions Of Hand Surgery Provided In The Office Vs. An Ambulatory Surgery Center, Trevor Tooley, James Feng, Jannat Khan, Paul Scott Shapiro

Conference Presentation Abstracts

INTRODUCTION: There is a growing body of literature supporting the efficacy, safety, and benefits of wide awake office-based low risk hand surgery. Procedures such as a carpal tunnel release are now, under the right clinical circumstances, being performed in the office-setting as opposed to a traditional operating room. While there is growing evidence supporting technique, procedure room setup, and cost analyses of office-based surgery, there is little investigation into the public perceptions of having surgery done in the office. Here we sought to evaluate public perceptions of undergoing low risk hand surgery in the office setting. METHODS: A prospective survey …

Documents From The March 8, 2023 Meeting Of The University Of Montana Staff Senate, University Of Montana--Missoula. Staff Senate

University of Montana Staff Senate Meeting Minutes

Agenda and meeting minutes from the March 8, 2023 meeting of the University of Montana Staff Senate.

Applications And Clinical Trial Landscape Using Toll-Like Receptor Agonists To Reduce The Toll Of Cancer, Christian Rolfo, Elisa Giovannetti, Pablo Martinez, Shannon Mccue, Aung Naing

Faculty, Staff and Student Publications

Toll-like receptors (TLRs), which serve as a bridge between innate and adaptive immunity, may be viable treatment targets. TLRs are the first line of defense against microbes and activate signaling cascades that induce immune and inflammatory responses. Patients with "hot" versus "cold" tumors may respond more favorably to immune checkpoint inhibition, and through their downstream effects, TLR agonists have the potential to convert "cold tumors" into "hot tumors" making TLRs in combination with immune checkpoint inhibitors, potential targets for cancer therapies. Imiquimod is a topical TLR7 agonist, approved by the FDA for antiviral and skin cancer treatments. Other TLR adjuvants …

Emotionally Concussed: The Impact Of Pre-Existing Anxiety On Concussion Recovery, Grace Szucs

Honors Program: Senior Projects (Public)

Recent advances in concussion research have shed light on numerous mental and physiological factors that may complicate concussion recovery. Systematic reviews of the existing literature have found that premorbid mental health conditions such as depression and anxiety may be a predictor of complicated concussion recovery, but studies have not had an appropriate design to isolate anxiety or depression as a predictor of lengthened recovery. This study investigated if athletes with a history of premorbid anxiety and/or depression would have a longer time of recovery than athletes without this history. Male and female athletes from a Division-1 athletic department treated for …

Raising Broilers, Tom Danko

UNH Cooperative Extension

Broilers are hybrid chickens bred for fast growth and finish. Typically raised to about 5 pounds, they are usually processed between 7 and 9 weeks of age. Birds slaughtered between 9 and 12 weeks of age, typically weigh between 7 and 10 lbs. and are called roasters.

Pragmatic, Prospective Comparative Effectiveness Trial Of Carbon Ion Therapy, Surgery, And Proton Therapy For The Management Of Pelvic Sarcomas (Soft Tissue/Bone) Involving The Bone: The Prosper Study Rationale And Design, Bradford S Hoppe, Ivy A Petersen, Benjamin K Wilke, Todd A Dewees, Reiko Imai, Eugen B Hug, Maria Rosaria Fiore, Jürgen Debus, Piero Fossati, Shigeru Yamada, Ester Orlandi, Qing Zhang, Cihang Bao, Katharina Seidensaal, Byron C May, Anna C Harrell, Matthew T Houdek, Laura A Vallow, Peter S Rose, Michael G Haddock, Jonathan B Ashman, Krista A Goulding, Steven Attia, Sunil Krishnan, Anita Mahajan, Robert L Foote, Nadia N Laack, Sameer R Keole, Chris J Beltran, Eric M Welch, Mohammed Karim, Safia K Ahmed

Faculty, Staff and Student Publications

Surgical treatment of pelvic sarcoma involving the bone is the standard of care but is associated with several sequelae and reduced functional quality of life (QOL). Treatment with photon and proton radiotherapy is associated with relapse. Carbon ion radiotherapy (CIRT) may reduce both relapse rates and treatment sequelae. The PROSPER study is a tricontinental, nonrandomized, prospective, three-arm, pragmatic trial evaluating treatments of pelvic sarcoma involving the bone. Patients aged at least 15 years are eligible for inclusion. Participants must have an Eastern Cooperative Oncology Group Performance Status score of two or less, newly diagnosed disease, and histopathologic confirmation of pelvic …

To Drink Or Not To Drink? Canada’S New Guidelines For Alcohol Consumption, Lauren Cutler

Cardozo International & Comparative Law Review (CICLR) Blog

On January 17, 2023, Canadian health officials from the Centre on Substance Abuse and Addiction released new guidelines for alcohol consumption, replacing a previous set from over ten years ago. These guidelines are reflective of “growing evidence, after decades of sometimes conflicting research, that even small amounts of alcohol can have serious health consequences.” In the technical summary, the Centre states that the costs associated with alcohol use in Canada in 2017 were a whopping $16.6 billion. $5.5 billion of that sum was attributable to healthcare costs.

This post was originally published on the Cardozo International & Comparative Law Review …

Whole Transcriptome-Based Skin Virome Profiling In Typical Epidermodysplasia Verruciformis Reveals Α-, Β-, And Γ-Hpv Infections, Amir Hossein Saeidian, Leila Youssefian, Mahtab Naji, Hamidreza Mahmoudi, Samantha M Barnada, Charles Huang, Karim Naghipoor, Amir Hozhabrpour, Jason S Park, Flavia Manzo Margiotta, Fatemeh Vahidnezhad, Zahra Saffarian, Kambiz Kamyab-Hesari, Mohammad Tolouei, Niloofar Faraji, Seyyede Zeinab Azimi, Ghazal Namdari, Parvin Mansouri, Jean-Laurent Casanova, Vivien Béziat, Emmanuelle Jouanguy, Jouni Uitto, Hassan Vahidnezhad

Department of Dermatology and Cutaneous Biology Faculty Papers

HPVs are DNA viruses include approximately 450 types that are classified into 5 genera (α-, β-, γ-, μ-, and ν-HPV). The γ- and β-HPVs are present in low copy numbers in healthy individuals; however, in patients with an inborn error of immunity, certain species of β-HPVs can cause epidermodysplasia verruciformis (EV), manifesting as recalcitrant cutaneous warts and skin cancer. EV presents as either typical or atypical. Manifestations of typical EV are limited to the skin and are caused by abnormal keratinocyte-intrinsic immunity to β-HPVs due to pathogenic sequence variants in TMC6, TMC8, or CIB1. We applied a transcriptome-based computational pipeline, …

Midweek Memo, Georgia Southern University

Midweek Memo

No abstract provided.

1915(C) Medicaid Waivers For Children With Severe Emotional Disturbance: Participant Characteristics, Enrollment, And Out-Of-Home Service Use, Genevieve Graaf, Emily Whitfield, Lonnie Snowden

SAGE Open Access Agreement Publications-Archive

Several states have invested in 1915(c) Home and Community Based Service (HCBS) Medicaid policies to improve outcomes and reduce costs for children and youth with significant behavioral health needs, or Severe Emotional Disturbance (SED). However, little is known about these programs and the children they serve. Through a retrospective cross-sectional analysis, this study aimed to understand if the program was successfully reaching its target population: children and youth with the highest clinical need, at the greatest risk for out-of-home care, and who may not otherwise be eligible for Medicaid through other avenues. Results describe the demographic, clinical, and service use …

Pragmatic, Prospective Comparative Effectiveness Trial Of Carbon Ion Therapy, Surgery, And Proton Therapy For The Management Of Pelvic Sarcomas (Soft Tissue/Bone) Involving The Bone: The Prosper Study Rationale And Design, Bradford S Hoppe, Ivy A Petersen, Benjamin K Wilke, Todd A Dewees, Reiko Imai, Eugen B Hug, Maria Rosaria Fiore, Jürgen Debus, Piero Fossati, Shigeru Yamada, Ester Orlandi, Qing Zhang, Cihang Bao, Katharina Seidensaal, Byron C May, Anna C Harrell, Matthew T Houdek, Laura A Vallow, Peter S Rose, Michael G Haddock, Jonathan B Ashman, Krista A Goulding, Steven Attia, Sunil Krishnan, Anita Mahajan, Robert L Foote, Nadia N Laack, Sameer R Keole, Chris J Beltran, Eric M Welch, Mohammed Karim, Safia K Ahmed

Faculty, Staff and Student Publications

Surgical treatment of pelvic sarcoma involving the bone is the standard of care but is associated with several sequelae and reduced functional quality of life (QOL). Treatment with photon and proton radiotherapy is associated with relapse. Carbon ion radiotherapy (CIRT) may reduce both relapse rates and treatment sequelae. The PROSPER study is a tricontinental, nonrandomized, prospective, three-arm, pragmatic trial evaluating treatments of pelvic sarcoma involving the bone. Patients aged at least 15 years are eligible for inclusion. Participants must have an Eastern Cooperative Oncology Group Performance Status score of two or less, newly diagnosed disease, and histopathologic confirmation of pelvic …

Young Astrocytic Mitochondria Attenuate The Elevated Level Of Ccl11 In The Aged Mice, Contributing To Cognitive Function Improvement, Ryosuke Tashiro, Dan Ozaki, Jesus Bautista-Garrido, Guanghua Sun, Lidiya Obertas, Alexis S Mobley, Gab Seok Kim, Jaroslaw Aronowski, Joo Eun Jung

Faculty, Staff and Student Publications

Aging drives cognitive decline, and mitochondrial dysfunction is a hallmark of age-induced neurodegeneration. Recently, we demonstrated that astrocytes secrete functional mitochondria (Mt), which help adjacent cells to resist damage and promote repair after neurological injuries. However, the relationship between age-dependent changes in astrocytic Mt function and cognitive decline remains poorly understood. Here, we established that aged astrocytes secret less functional Mt compared to young astrocytes. We found the aging factor C-C motif chemokine 11 (CCL11) is elevated in the hippocampus of aged mice, and that its level is reduced upon systemic administration of young Mt, in vivo. Aged mice receiving …

Optimization Of Cryo-Electron Microscopy For Quantitative Analysis Of Lipid Bilayers, Frederick A Heberle, Doug Welsch, Haden L Scott, M Neal Waxham

Faculty, Staff and Student Publications

Cryogenic electron microscopy (cryo-EM) is among the most powerful tools available for interrogating nanoscale structure of biological materials. We recently showed that cryo-EM can be used to measure the bilayer thickness of lipid vesicles and biological membranes with subangstrom precision, resulting in the direct visualization of nanoscopic domains of different thickness in multicomponent lipid mixtures and giant plasma membrane vesicles. Despite the great potential of cryo-EM for revealing the lateral organization of biomembranes, a large parameter space of experimental conditions remains to be optimized. Here, we systematically investigate the influence of instrument parameters and image postprocessing steps on the ability …

2023-03-08 The Seattle Blues, Hisham Bensaadat

The Spectator Online

No abstract provided.