Digital Commons Network^™

Biased But Reasonable: Bias Under The Cover Of Standard Of Care, Maytal Gilboa

Georgia Law Review

Inequities in the distribution of healthcare are widely acknowledged to plague the United States healthcare system. Controversies as to whether anti-discrimination law allows individuals to bring lawsuits with respect to implicit rather than intentional bias render negligence law an important avenue for redressing harms caused by implicit bias in medical care. Yet, as this Article argues, the focus of negligence law on medical standards of care to define the boundaries of healthcare providers’ legal duty of care prevents the law from adequately deterring implicit bias and leaves patients harmed by biased treatment decisions without redress for their losses, so long …

Privacy Is Not Dead: Expressively Using Law To Push Back Against Corporate Deregulators And Meaningfully Protect Data Privacy Rights, Alexander F. Krupp

Georgia Law Review

When the European Union’s (EU) General Data Protection Regulation (GDPR) passed in 2016, it represented the world’s first major comprehensive data privacy law and kicked off a conversation about how we think about the right to privacy in the modern age. The law granted a broad range of rights to EU citizens, including a right to have companies delete data they collect about you, a right not to have your personal information sold, and a range of other rights all geared towards individual autonomy over personal data. All the while, platform companies like Facebook (Meta), Apple, and Amazon have taken …

March 9, 2023, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Shorter Length Of Stay And Increased Return To Work With Cervical Disc Arthroplasty Versus Anterior Cervical Discectomy And Fusion, Philip Zakko, Alex Miller, Daniel K. Park, Jad Khalil

Conference Presentation Abstracts

INTRODUCTION: Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) are established surgical options for the treatment of cervical radiculopathy, myelopathy, and cervical degenerative disc disease. However, current literature does not demonstrate a clear benefit between ACDF or CDA. The primary objective of this study is to compare the outcomes of ACDF and CDA for patients enrolled in the Michigan Spine Surgery Improvement Collaborative (MSSIC) database. Secondary objectives include assessment of early complications, procedural/perioperative outcomes, and patient-reported outcome measures after both ACDF and CDA. METHODS: Patients undergoing 1 or 2 level ACDF or CDA surgery were included. A …

Take Back Your Power: 10 New Rules For Women At Work Book Review, Tomi Daniel

Journal of Social, Behavioral, and Health Sciences

Deb Liu wrote Take Back Your Power to contribute her insights to the reckoning around the power imbalance that continues to disadvantage women in the workforce. The author reiterated that women must take back their power—whether they ceded it, had it taken from them, or never had it given them in the first place. Take Back Your Power is 240 pages of the author’s personal anecdotes and case studies of other women who experienced different nuances of power imbalance at work and how they overcame them. Written by a respected female leader who inched her way to the top in …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

Youth Mental Health Issues on the Rise: National Youth Advocacy and Resilience Research Center Awards Seed Grants for Faculty Research in Support of Local Youth Advocacy and Resiliency

Business Innovation Group Announces Patrick Woock as New Director of Business Incubation

Pedicle Screw-Associated Violation Of The Adjacent Unfused Facet Joint: Clinical Outcomes And Fusion Rates, Nathan J. Sinz, David Hanwuk Kim, Raymond W. Hwang, Gyu-Ho Lee, Kevin Charles Baker, Rick C. Sasso, Daniel K. Park, Jeffrey S. Fischgrund, Ruijia Niu

Conference Presentation Abstracts

INTRODUCTION: Lumbar spine pedicle screws are the most commonly utilized implants for providing immediate spinal stability during fusion surgery. Ideal pedicle screw positioning includes avoiding violation of any adjacent unfused facet joints. Nevertheless, inadvertent screw malposition and screw-associated violation of adjacent facet joints (FJV) remains a potential complication of the procedure regardless of whether surgery is performed in open fashion or with minimally invasive techniques and despite the use of intraoperative imaging or surgical navigation. Given the proximity of the lumbar vertebral pedicle to the proximal facet joint, FJV occurs almost exclusively at the level of the proximal as opposed …

Health And Kinesiology News, Georgia Southern University

Health Sciences & Kinesiology: News & Publications (2015-2023)

• Graduate Sport Management Program Receives Two Rankings

Real-Time Liver Tumor Localization Via Combined Surface Imaging And A Single X-Ray Projection, Hua-Chieh Shao, Yunxiang Li, Jing Wang, Steve Jiang, You Zhang

Faculty, Staff and Student Publications

Objective. Real-time imaging, a building block of real-time adaptive radiotherapy, provides instantaneous knowledge of anatomical motion to drive delivery adaptation to improve patient safety and treatment efficacy. The temporal constraint of real-time imaging (< 500 milliseconds) significantly limits the imaging signals that can be acquired, rendering volumetric imaging and 3D tumor localization extremely challenging. Real-time liver imaging is particularly difficult, compounded by the low soft tissue contrast within the liver. We proposed a deep learning (DL)-based framework (Surf-X-Bio), to track 3D liver tumor motion in real-time from combined optical surface image and a single on-board x-ray projection.

Approach. Surf-X-Bio performs mesh-based deformable registration to track/localize liver tumors volumetrically via three steps. First, a DL model was built to estimate liver boundary motion from an optical surface image, using learnt motion correlations between the respiratory-induced external body surface and liver boundary. Second, the residual liver boundary motion estimation error was further corrected by a graph neural network-based DL model, using information extracted from a …

Perspectives On Lifespan Religious And Spiritual Development From Scholars Across The Lifespan, Megan Gale, Justin J. Hendricks, David C. Dollahite, Loren D. Marks

Faculty Publications

The purpose of the article is to share our perspectives on the key influences of lifespan religious and spiritual development as scholars from across the lifespan (i.e., the four authors are from different generations, including Baby Boomers, Generation X, Millennials, and Gen Z). Our perspectives are heavily influenced by our combined 60+ years of research experience in examining the connections between religion and family life. Our discussion is organized around Bronfenbrenner’s bioecological framework and the process-person-context-time model. Within this framework, the key factors we discuss that influence religious/spiritual development include (a) process (i.e., person-religion mismatch and family processes), (b) person …

Who Cares? A Scoping Review On Intellectual Disability, Epilepsy And Social Care, Hannah Newman, Sonya Rudra, Lisa Burrows, Samuel Tromans, Lance Watkins, Paraskevi Triantafyllopoulou, Angela Hassiotis, Alexandra Gabrielsson, Rohit Shankar

Peninsula Medical School

PurposeNearly a quarter of people with Intellectual disability (PwID) have epilepsy. Many have seizures across their lifetime. In the UK supporting their epilepsy linked risks and needs, particularly in professional care settings and in the community, requires significant social care input. Therefore, the interface between social and health care services is important. This study aim is to identify key intersectional areas of social provision for PWID and epilepsy.MethodsA scoping review of the literature was performed in accordance with PRISMA guidance with suitable search terms. The search was completed in CINAHL, Embase, Psych INFO, SCIE, and Cochrane electronic databases by an …

"Please Don't Assess Him To Destruction": The R.A.I.S.E. Assessment Framework For Primary Progressive Aphasia, Jeanne Gallée, Jade Cartwright, Anna Volkmer, Anne Whitworth, Deborah Hersh

Research outputs 2022 to 2026

Purpose: Speech-language pathologists (SLPs) assess people with primary progressive aphasia (PPA) through measurements of speech, language, communication, and well-being, with the aims of identifying challenges and strengths, monitoring change, and informing treatment directions and supports. The purpose of this clinical focus article is to highlight the necessity for person-centered assessment specific to PPA and to conceptualize a framework that acknowledges the multifaceted nature of assessment for this population. In this framework, the unique challenges posed by a diagnosis of PPA are addressed with the aim to provide practical guidance for clinicians and to support reflection on current practices. Method: In …

The Child And Dependent Care Credit: Unlike Trix, Not Just For Kids, Gabrielle Pepin, Yulya Truskinovsky

Upjohn Institute Policy and Research Briefs

No abstract provided.

Cocktail-Party Listening And Cognitive Abilities Show Strong Pleiotropy, Samuel R. Mathias, Emma M. Knowles, Josephine Mollon, Peter T. Fox, Rene L. Olvera, Juan M. Peralta, Satish Kumar, Harald H. H. Goring, Ravi Duggirala, Joanne E. Curran, John Blangero, David C. Glahn

School of Medicine Publications

Introduction: The cocktail-party problem refers to the difficulty listeners face when trying to attend to relevant sounds that are mixed with irrelevant ones. Previous studies have shown that solving these problems relies on perceptual as well as cognitive processes. Previously, we showed that speech-reception thresholds (SRTs) on a cocktail-party listening task were influenced by genetic factors. Here, we estimated the degree to which these genetic factors overlapped with those influencing cognitive abilities.

Methods: We measured SRTs and hearing thresholds (HTs) in 493 listeners, who ranged in age from 18 to 91 years old. The same individuals completed a cognitive test …

Neurofibromatosis Type 1-Dependent Alterations In Mouse Microglia Function Are Not Cell-Intrinsic, Francesca Logiacco, Laura Cathleen Grzegorzek, Elizabeth C Cordell, Oliver Popp, Philipp Mertins, David H Gutmann, Helmut Kettenmann, Marcus Semtner

2020-Current year OA Pubs

We previously discovered a sex-by-genotype defect in microglia function using a heterozygous germline knockout mouse model of Neurofibromatosis type 1 (Nf1 ± mice), in which only microglia from male Nf1 ± mice exhibited defects in purinergic signaling. Herein, we leveraged an unbiased proteomic approach to demonstrate that male, but not female, heterozygous Nf1 ± microglia exhibit differences in protein expression, which largely reflect pathways involved in cytoskeletal organization. In keeping with these predicted defects in cytoskeletal function, only male Nf1 ± microglia had reduced process arborization and surveillance capacity. To determine whether these microglial defects were cell autonomous or reflected …

Longitudinal Ultrasound Imaging And Network Modeling In Rats Reveal Sex-Dependent Suppression Of Liver Regeneration After Resection In Alcoholic Liver Disease, Benjamin K. Barnhart, Toshiki Kan, Ankita Srivastava, Corinne E. Wessner, John Waters, Manju Ambelil, John R. Eisenbrey, Jan B. Hoek, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Liver resection is an important surgical technique in the treatment of cancers and transplantation. We used ultrasound imaging to study the dynamics of liver regeneration following two-thirds partial hepatectomy (PHx) in male and female rats fed via Lieber-deCarli liquid diet protocol of ethanol or isocaloric control or chow for 5–7 weeks. Ethanol-fed male rats did not recover liver volume to the pre-surgery levels over the course of 2 weeks after surgery. By contrast, ethanol-fed female rats as well as controls of both sexes showed normal volume recovery. Contrary to expectations, transient increases in both portal and hepatic artery blood flow …

Role Of Klotho And Age/Rage-Wnt/Β-Catenin Signalling Pathway On The Development Of Cardiac And Renal Fibrosis In Diabetes, Beatriz Martín-Carro, Julia Martín-Vírgala, Sara Fernández-Villabrille, Alejandra Fernández-Fernández, Marcos Pérez-Basterrechea, Juan F Navarro-González, Javier Donate-Correa, Carmen Mora-Fernández, Adriana S Dusso, Natalia Carrillo-López, Sara Panizo, Manuel Naves-Díaz, José L Fernández-Martín, Jorge B Cannata-Andía, Cristina Alonso-Montes

2020-Current year OA Pubs

Fibrosis plays an important role in the pathogenesis of long-term diabetic complications and contributes to the development of cardiac and renal dysfunction. The aim of this experimental study, performed in a long-term rat model, which resembles type 1 diabetes mellitus, was to investigate the role of soluble Klotho (sKlotho), advanced glycation end products (AGEs)/receptor for AGEs (RAGE), fibrotic Wnt/β-catenin pathway, and pro-fibrotic pathways in kidney and heart. Diabetes was induced by streptozotocin. Glycaemia was maintained by insulin administration for 24 weeks. Serum and urine sKlotho, AGEs, soluble RAGE (sRAGE) and biochemical markers were studied. The levels of Klotho, RAGEs, ADAM10, …

Against God, Good Faith, And Reason: The 1381 Peasants’ Revolt In Cambridge, Reagan T. Vernon

USF Tampa Graduate Theses and Dissertations

This paper focuses on the Peasants’ Revolt of 1381 as it occurred in the university town of Cambridge. The historiographic understanding of the Cambridge wing of the Peasants’ Revolt has categorized it as foundationally motivated by town and gown resentment. Using legal records and chronicle accounts, this thesis demonstrates that the crowd did not exclusively target the university. As one of the town’s wealthier and increasingly authoritative institutions, the university and its constituents were targets in the uprising—but this was in addition to several attacks on local churches, monastic institutions, and manors. These attacks against higher authorities reflect a loss …

Of Mētis And Cuttlefish: Employing Collective Mētis As A Theoretical Framework For Marginalized Communities, Justiss Wilder Burry

USF Tampa Graduate Theses and Dissertations

This LGBTQ+ rhetoric of health and medicine (RHM) community-based research explores the ways community members and queer community participants communicate about potential intimate partner selection in Central Florida. The dissertation introduces the theoretical framework of “collective mētis” as a way to analyze and discuss community communication against Florida’s required HIV disclosure laws that attempt to medicalize this and control this community’s intimate partner selection. Research questions include: 1) How do people in counterpublic enclaves (Chávez, 2011) communicate their potential intimate partner desires to others in the community including the types of disclosures they express and negotiate, and how? 2) How …

Effective Connectivity Of Functional Mri Via Deep Learning Methods, Kai-Cheng Chuang

LSU Doctoral Dissertations

Effective connectivity, based on functional magnetic resonance imaging (fMRI) time series signals, is the quantification of how strongly brain activity in a certain source brain region contributes to brain activity in a target brain region, independent of the contributions of other source regions. Current methods to solve this problem have several limitations. They are either unable to model nonlinear relationships between source and target signals, unable to efficiently quantify time lags in source-target relationships, unable to identify time-varying relationships, or fail to account for variability in the hemodynamic response function that converts neuron activity to a measurable signal. In this …

Engineering T Cells To Suppress Acute Gvhd And Leukemia Relapse After Allogeneic Hematopoietic Stem Cell Transplantation, Feiyan Mo, Norihiro Watanabe, Kayleigh I Omdahl, Phillip M Burkhardt, Xiaoyun Ding, Eiko Hayase, Angela Panoskaltsis-Mortari, Robert R Jenq, Helen E Heslop, Leslie S Kean, Malcolm K Brenner, Victor Tkachev, Maksim Mamonkin

Faculty, Staff and Student Publications

Acute graft-versus-host disease (aGVHD) limits the therapeutic benefit of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and requires immunosuppressive prophylaxis that compromises antitumor and antipathogen immunity. OX40 is a costimulatory receptor upregulated on circulating T cells in aGVHD and plays a central role in driving the expansion of alloreactive T cells. Here, we show that OX40 is also upregulated on T cells infiltrating GVHD target organs in a rhesus macaque model, supporting the hypothesis that targeted ablation of OX40+ T cells will mitigate GVHD pathogenesis. We thus created an OX40-specific cytotoxic receptor that, when expressed on human T cells, enables selective …

Nirogacestat, A Γ-Secretase Inhibitor For Desmoid Tumors, Mrinal Gounder, Brian A Van Tine, Et Al.

2020-Current year OA Pubs

BACKGROUND: Desmoid tumors are rare, locally aggressive, highly recurrent soft-tissue tumors without approved treatments.

METHODS: We conducted a phase 3, international, double-blind, randomized, placebo-controlled trial of nirogacestat in adults with progressing desmoid tumors according to the Response Evaluation Criteria in Solid Tumors, version 1.1. Patients were assigned in a 1:1 ratio to receive the oral γ-secretase inhibitor nirogacestat (150 mg) or placebo twice daily. The primary end point was progression-free survival.

RESULTS: From May 2019 through August 2020, a total of 70 patients were assigned to receive nirogacestat and 72 to receive placebo. Nirogacestat had a significant progression-free survival benefit …

The Tetraspanin Cd53 Protects Stressed Hematopoietic Stem Cells Via Promotion Of Dream Complex-Mediated Quiescence, Zev J Greenberg, Luana Chiquetto Paracatu, Darlene A Monlish, Qian Dong, Michael Rettig, Nate Roundy, Rofaida Gaballa, Weikai Li, Wei Yang, Cliff J Luke, Laura G Schuettpelz

2020-Current year OA Pubs

The hematopoietic stem cell (HSC) cycle responds to inflammatory and other proliferative stressors; however, these cells must quickly return to quiescence to avoid exhaustion and maintain their functional integrity. The mechanisms that regulate this return to quiescence are not well understood. Here, we show that tetraspanin CD53 is markedly upregulated in HSCs in response to a variety of inflammatory and proliferative stimuli and that the loss of CD53 is associated with prolonged cycling and reduced HSC function in the context of inflammatory stress. Mechanistically, CD53 promotes the activity of the dimerization partner, RB-like, E2F, and multi-vulva class B (DREAM) transcriptional …

Prevalence Of Potentially Traumatic Events And Symptoms Of Depression, Anxiety, Hazardous Alcohol Use, And Post-Traumatic Stress Disorder Among People With Hiv Initiating Hiv Care In Cameroon, Angela M Parcesepe, Lindsey M Filiatreau, Peter Vanes Ebasone, Anastase Dzudie, Brian W Pence, Milton Wainberg, Marcel Yotebieng, Kathryn Anastos, Eric Pefura-Yone, Denis Nsame, Rogers Ajeh, Denis Nash

2020-Current year OA Pubs

BACKGROUND: This study explored the relationship between specific types of potentially traumatic events (PTEs) and symptoms of mental health disorders among people with HIV (PWH) in Cameroon.

METHODS: We conducted a cross-sectional study with 426 PWH in Cameroon between 2019-2020. Multivariable log binominal regression was used to estimate the association between exposure (yes/no) to six distinct types of PTE and symptoms of depression (Patient Health Questionnaire-9 score > 9), PTSD (PTSD Checklist for DSM-5 score > 30), anxiety (Generalized Anxiety Disorder-7 scale score > 9), and hazardous alcohol use (Alcohol Use Disorders Identification Test score > 7 for men; > 6 for women).

RESULTS: A …

The Repercussions Of The Corona Pandemic On Zayed University Students In Terms Of Psychological Aspects، Ways Of Thinking And Learning Methods, Sawsan Alskaf

An-Najah University Journal for Research - B (Humanities)

The study aimed at investigating the extent of the Covid-19 pandemic repercussions on the Zayed University student’s mentality by looking at the methods of adaptation with the news regarding it، and their attitudes towards shifting to the use of online platforms to persevere education. The researcher has done a special survey consisting on (25) paragraphs divided into three categories that has addressed results based upon the levels of mental anxiety of students between males and females. This process was conducted following the country and university efforts in facing the pandemic while continuing education using suitable and credible online platforms following …

“I’Ve Got Out At Last”: The Subversion Of Hegemonic Masculinity In Charlotte Perkins Gilman’S “The Yellow Wallpaper”, Ahmad Qabaha, Bilal Hamamra

An-Najah University Journal for Research - B (Humanities)

Drawing on Raewyn Connell’s concept “hegemonic masculinity” and engaging the critical line of feminism, this article argues that Gilman’s “The Yellow Wallpaper” unearths the institutional dynamics that sustain the masculine hegemonic discourse. This article reads this short story as counter-hegemony, the narrator of which critiques what Gramsci called “manufacture of consent”, wherein ideas and beliefs are shaped, and hegemony is reproduced, through culture. We argue that Gilman accounts for the ways in which gender hierarchy is maintained through consent rather than force, and she endorses a struggle over ideas and beliefs to create counter-hegemony that contests socially-constructed dominant ideas and …

Spatial Analysis Of Bank Locations In Irbid As An Indicator Of Urban Development, Qasem Al-Dowikat, Safaa Al-Wedyan

An-Najah University Journal for Research - B (Humanities)

This study aimed to reveal the spatial distribution pattern of Banks in the city of Irbid/Jordan. And analysis of variables that influenced the formation of this pattern. The study applied historical approach to trace the spatial spread of Banks, and how they relate to the stages of the city’s growth. Descriptive analytical approachis also appliedtoreveal the relationship between the distribution of Banks and population densities. Statistical and Cartographic analysis within (GIS) is used as well. Results showed a tremendous variation in the distribution of Banks among the areas, revealing a clear clustered pattern. Population density was not an affecting variable. …

The Effect Of A Proposed Training Program For The Foundation Course On Basic Skills And Body Composition Among Members Of Karate Clubs In The Governorate Of Jenin - Palestine, Ismail Zakarnah, Ghaith Nasief, Ahmad Nassar, Nashat Jabareen

An-Najah University Journal for Research - B (Humanities)

The study aimed to identify the effect of a proposed training program for the foundation course of the basic skills and body composition of the members of karate clubs in the governorate of Jenin – Palestine. The researchers used the experimental approach due to its suitability to the nature and objectives of the study. To achieve this, the study was conducted on a carefully chosen sample of karate clubs (the Talented Academy of Physical Fitness and self Defense, Arrabah Karate Club and Zababdeh Karate Club). The sample consisted of 50 members, 10 of those members were of exploratory sample, and …

Endnotes, Sdlp

Sustainable Development Law & Policy

No abstract provided.

Toxic Criminals: Prosecuting Individuals For Hazardous Waste Crimes Under The United States Resource Conservation And Recovery Act, Dr. Joshua Ozymy, Dr. Melissa Jarrell Ozymy

Sustainable Development Law & Policy

The U.S. Resource Conservation and Recovery Act (“RCRA”) contains criminal provisions which allow prosecutors to seek substantial penalties when individuals commit hazardous waste crimes involving significant harm or culpable conduct. However, our empirical understanding of enforcement outcomes is limited. We used content analysis of 2,728 criminal prosecutions derived from U.S. EPA criminal investigations from 1983 to 2021 and examined all prosecutions of individual defendants for RCRA violations. Our results show that 222 prosecutions were adjudicated, with over $72.9 million in monetary penalties, 755 years of probation, and 451 years of incarceration levied at sentencing. Seventeen percent of prosecutions centered on …