Digital Commons Network^™

High-Resolution 1h Nmr Analysis Of Continuous And Discontinuous Thermo-Oxidative Susceptibility Of Culinary Oils During Frying At 180℃, Gilbert Ampem, Adam Le Gresley, Martin Grootveld, Declan P Naughton

Journal of Food and Drug Analysis

Lipid oxidations products (LOPs) are reactive mutagenic and carcinogenic species known to be generated in thermally stressed culinary oils. Mapping the evolution of LOPs in culinary oils exposed to standard frying practices – both continuous and discontinuous thermo-oxidation – at 180℃ is vital to our understanding of these processes, and to the development of scientific solutions for their effective suppression. Modifications in the chemical compositions of the thermo-oxidised oils were analysed using a high-resolution proton nuclear magnetic resonance (¹H NMR) technique. Research findings acquired showed that polyunsaturated fatty acid (PUFA)-rich culinary oils were the most susceptible to thermo-oxidation. …

Investigation Of Monacolin K, Yellow Pigments, And Citrinin Production Capabilities Of Monascus Purpureus And Monascus Ruber (Monascus Pilosus), Tzu-Shing Lin, Shih-Hau Chiu, Chien-Chi Chen, Chih-Hui Lin

Journal of Food and Drug Analysis

Red mold rice (RMR) is a traditional Chinese medicine prepared using Monascus fermentation. M. ruber (pilosus) and M. purpureus have a long history of use as food and medicine. As an economically important starter culture, the relationship between the taxonomy of Monascus and production capabilities of secondary metabolites is crucial for the Monascus food industry. In this study, monacolin K, monascin, ankaflavin, and citrinin production by M. purpureus and M. ruber were genomically and chemically investigated. Our findings suggest that M. purpureus can produce monascin and ankaflavin in a correlated manner, whereas M. ruber produces monascin with minimum …

Determination Of 24 Sulfonamide Antibiotics In Instant Pastries By Modified Quechers Coupled With Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry, Shuo Li, Can Zhang, Hui-Xin Tang, Yue Gu, Ai-Jing Guo, Ke Wang, Kao-Qi Lian

Journal of Food and Drug Analysis

There were few reports about antibiotic residues in egg-containing products. In the study, an effective method for the simultaneous determination of 24 sulfonamide antibiotics in two instant pastries based on a modified QuEChERS sample preparation technique coupled with ultra performance liquid chromatography-tandem mass spectrometry was developed. The results show that the average recoveries of the SAs at 5, 10, and 50 µg·kg^-1 levels were 67.6%-103.8%, with relative standard deviations (RSD) of 0.80-9.23%. The limit of detections (LODs) and limit of quantitations (LOQs) were 0.01-0.14 µg∙kg^-1 and 0.02-0.45 µg∙kg^-1, respectively. This method was suitable for analysis of …

Simultaneous Determination Of 24 Congeners Of 2- And 3‑Monochloropropanediol Esters And 7 Congeners Of Glycidyl Esters Using Direct Multi-Residue Analytical Lc-Ms/Ms Methods In Various Food Matrices, Ching-Chang Lee, Bo-Lun Lin, Yi-Wen Huang, Ning-Syuan Hsu, Wei-Hsiang Chang

Journal of Food and Drug Analysis

Glycidyl esters (GEs) and 2- and 3-monochloropropanediol esters (MCPDEs) are emerging process-generated food contaminants known as possible carcinogens. Herein, a direct method is developed and validated for the first time to simultaneously quantify seven GEs and twenty-four MCPDE congeners of processed foods using liquid chromatography-tandem mass spectrometry in a single sequence without ester cleavage or derivatisation, thereby allowing for the simultaneous analysis of numerous food matrices with high accuracy and precision. Our results show levels of GEs varying from

Erinacine S From Hericium Erinaceus Mycelium Promotes Neuronal Regeneration By Inducing Neurosteroids Accumulation, Chun-Yu Lin, Yi-Ju Chen, Chih-Hsuan Hsu, Yu-Hsuan Lin, Peng-Tzu Chen, Ting-Han Kuo, Chris T. Ho, Hsin-Hua Chen, Sih-Jia Huang, Ho-Chieh Chiu, Chin-Chu Chen, Eric Hwang

Journal of Food and Drug Analysis

Erinacines derived from Hericium erinaceus have been shown to possess various health benefits including neuroprotective effect against neurodegenerative diseases, yet the underlying mechanism remains unknown. Here we found that erinacine S enhances neurite outgrowth in a cell autonomous fashion. It promotes post-injury axon regeneration of PNS neurons and enhances regeneration on inhibitory substrates of CNS neurons. Using RNA-seq and bioinformatic analyses, erinacine S was found to cause the accumulation of neurosteroids in neurons. ELISA and neurosteroidogenesis inhibitor assays were performed to validate this effect. This research uncovers a previously unknown effect of erinacine S on raising the level of neurosteroids.

Regulatory Considerations For Generic Products Of Non-Biological Complex Drugs, Yu-Hsuan Liu, Yi-Shuo Chen, Ting Tseng, Min-Lin Jiang, Churn-Shiouh Gau, Lin-Chau Chang

Journal of Food and Drug Analysis

The Non-Biological Complex Drug (NBCD) Working Group defines an NBCD as “a medicinal product, not being a biological medicine, where the active substance is not a homo-molecular structure, but consists of different (closely related and often nanoparticulate) structures that cannot be isolated and fully quantitated, characterized and/or described by physicochemical analytical means”. There are concerns about the potential clinical differences between the follow-on versions and the originator products and within the individual follow-on versions. In the present study, we compare the regulatory requirements for developing generic products of NBCDs in the European Union (EU) and the United States (US). The …

Recent Developments In Detection And Therapeutic Approaches For Antibiotic-Resistant Bacterial Infections, Kavya Moorthy, Kai-Chih Chang, Hsueh-Hui Yang, Wen-Min Su, Cheng-Kang Chiang, Zhiqin Yuan

Journal of Food and Drug Analysis

Owing to the widespread emergence and proliferation of antibiotic-resistant bacteria, the therapeutic benefits of antibiotics have been reduced. In addition, the ongoing evolution of multidrug-resistant pathogens poses a challenge for the scientific community to develop sensitive analytical methods and innovative antimicrobial agents for the detection and treatment of drug-resistant bacterial infections. In this review, we have described the antibiotic resistance mechanisms that occur in bacteria and summarized the recent developments in detection strategies for monitoring drug resistance using different diagnostic methods in three aspects, including electrostatic attraction, chemical reaction, and probe-free analysis. Additionally, to understand the effective inhibition of drug-resistant …

Elderly Or Disabled Registered Sex Offenders: Are They Experiencing Cruel And Unusual Punishment Under Ohio Sex Offender Classification And Registration Laws?, Susana Tolentino

University of Cincinnati Law Review

No abstract provided.

We[Ed] The People: How A Broader Interpretation Of The Rohrabacher-Farr Amendment Effectuates The Changing Social Policy Surrounding Medical Marijuana, Tess A. Chaffee

University of Cincinnati Law Review

No abstract provided.

Taking The American Dream – A Remedy For Home Equity Theft Following The Sixth Circuit's Ruling In Harrison V. Montgomery County, Ohio, Elizabeth Black

University of Cincinnati Law Review

No abstract provided.

A Vision Of The Anti-Racist Public Corporation, Steven A. Ramirez

University of Cincinnati Law Review

No abstract provided.

Markets As Legal Constructions, Gregory Brazeal

University of Cincinnati Law Review

Since at least the late 1970s, popular political and economic debates in the United States have often been framed in terms of a choice between “government” and “the market.” In addition, debates have often assumed that “the market” is associated with freedom while government “regulation” or “interference in the market” constitutes oppression.

This article begins by making the familiar observation that the distinction between “government” and “the market,” at least when taken at face value, makes no sense. Even idealized laissez-faire markets are creatures of the state and its market-structuring laws, including criminal law and the laws of property, contracts, …

Comparison Of Flex Vs. Residential Clinical Education Program Outcomes: Physical Therapy Students’ Self-Efficacy, Confidence, And Clinical Competence, Derrick F. Campbell, Jean-Michel Brismée, Brad S. Allen, Troy Hooper, Manuel A. Domenech, Kathleen Manella

Education Collection

Purpose: Alternative flexible (Flex) path Doctor of Physical Therapy (DPT) programs may have an emerging footprint. The differences between Flex and traditional residential DPT program clinical experience outcomes remain unknown. The purpose of this study was to evaluate Flex and residential DPT students’ clinical reasoning self-efficacy, confidence with treating, and Clinical Performance Instrument (CPI) clinical reasoning and summative scores during clinical experiences.

Methods: A descriptive and exploratory cross-sectional survey was used with a voluntary convenience sample of 211 university DPT students during Fall 2020 full-time clinical experiences. Descriptive and inferential statistics evaluated differences in Flex and residential DPT program …

Decoding Dei: Liberatory Practices Grounded In Community, Lucia Leon, Julia Van Der Ryn, Emily Wu

Center for Community Engagement | Presentations

No abstract provided.

Water Challenges In Socio-Ecological Systems: Is Human Decision-Making Accounted For In The Analysis Of Climate Change Adaptation Options?, Sara Zanini

Fondazione Eni Enrico Mattei Working Papers

This mixed-method systematic review is motivated by the willingness to identify the efforts of the most recent developments of the literature on the understanding of water challenges in socioecological systems, particularly coastal ones. The attention, in the exercise, is directed at the analysis of individual and collective decision-making processes concerning the use of the environmental good. This is because ultimately, if it is true that water resources are affected by external trends and shocks, it is also relevant how distinct paths of local and regional level responses impact on resource status. The inquiry, departs from a conceptual point of view …

Core And Periphery In Constitutional Law, R. George Wright

William & Mary Law Review Online

This paper embarks on an excursion through a number of the most vital constitutional rights cases, and other contexts as well, and seeks to show that the recurring judicial attempts to distinguish between core and peripheral areas within any given broad constitutional right are unnecessary and distracting. Intriguingly, the case for this conclusion varies significantly depending upon the nature of the general constitutional right in question. But the overall lesson is that courts should abandon their attempts to distinguish between core and peripheral areas of any given broad constitutional right. Courts should instead focus—directly or indirectly—on their best assessment of …

Smith Family Papers (Sc 3679), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid, scans and typescripts (Click on "Additional Files" below) for Manuscripts Small Collection 3679. Two items relating to the Smith family of Warren County, Kentucky: a letter, 18 November 1852, from Amanda M. F. Withers, Dripping Spring, Edmonson County, Kentucky, to Sarah Hampton in Warren County; having recently moved, she describes her labors setting up housekeeping, gives regards to her friends and Sarah’s family, advises Sarah to be careful in choosing a husband, and asks to be sent some plant cuttings. Also, a codicil to the will of Sarah’s future father-in-law Daniel C. Smith, 1868.

Minutes 3-10-2023 | Institutional Effectiveness, Writing Across The Curriculum Subcommittee, Andrea Porter, Katelyn Walker

Institutional Effectiveness Committee Minutes

No abstract provided.

Comparison Of Flex Vs. Residential Clinical Education Program Outcomes: Physical Therapy Students’ Self-Efficacy, Confidence, And Clinical Competence, Derrick F. Campbell, Jean-Michel Brismee, Brad Allen, Troy L. Hooper, Manuel A. Domenech, Kathleen J. Manella

HPD Articles

Purpose: Alternative flexible (Flex) path Doctor of Physical Therapy (DPT) programs may have an emerging footprint. The differences between Flex and traditional residential DPT program clinical experience outcomes remain unknown. The purpose of this study was to evaluate Flex and residential DPT students’ clinical reasoning self-efficacy, confidence with treating, and Clinical Performance Instrument (CPI) clinical reasoning and summative scores during clinical experiences.

Methods: A descriptive and exploratory cross-sectional survey was used with a voluntary convenience sample of 211 university DPT students during Fall 2020 full-time clinical experiences. Descriptive and inferential statistics evaluated differences in Flex and residential DPT program students’ …

20230310_Spring Break Hours, Brandon Carroll

HSLIC Blog Post

No abstract provided.

2023-03-10 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Narcotic Requirements Before And After Implementation Of Buccal Nerve Blocks For Buccal Mucosa Graft Harvest: Technique And Retrospective Review., Adam Nolte, Alejandra Perez, Chase Mallory, Timothy Demus, Jessica Boyer, Scott Jamieson, Dhaval Jivanji, Billy Cordon

HPD Articles

The reduction in opioid use has become a public health priority. We aimed to assess if performing buccal nerve blocks (BNB) at the time of buccal mucosa graft (BMG) harvest impacts post-operative narcotic usage in the inpatient setting. We retrospectively reviewed clinical characteristics and morphine milligram equivalents (MMEs) received for all patients that underwent a BMG urethroplasty at our institution. The primary outcome measure was post-operative MMEs for patients before and after implementing the BNB. We identified 74 patients that underwent BMG urethroplasty, 37 of which were before the implementation of the BNB and 37 of which were after. No …

Spine Bracing: When To Utilize-A Narrative Review., John L Cerillo, Alexander N Becsey, Chai P Sanghadia, Kevin T Root, Brandon Lucke-Wold

HPD Articles

Spinal bracing is a common non-surgical technique that allows clinicians to prevent and correct malformations or injuries of a patient's spinal column. This review will explore the current standards of practice on spinal brace utilization. Specifically, it will highlight bracing usage in traumatic injuries, pregnancy, pediatrics, osteoporosis, and hyperkyphosis; address radiological findings concurrent with brace usage; and provide an overview of the braces currently available and advancements in the field. In doing so, we aim to improve clinicians' understanding and knowledge of bracing in common spinal pathologies to promote their appropriate use and improve patient outcomes.

Fobian Named 2023 Routh Early Career Award Recipient, Brianna Hoge

Browse All News

No abstract provided.

University Budget Advisory Committee Presentation (March 10, 2023), Csusb Budget Office

University Budget Office records

No abstract provided.

Call Numbers, Oh Call Numbers On Ebooks, Why Have You Forsaken Us!, David Schuster, Sasha Frizzell

Library Scholarship

ILS vendor Knowledge bases (KB) are built in a black box. The quality of the metadata is not the concern of the ILS vendor which then leads to missing data, which impacts discoverability. Comparing records of two ILS vendors KBs has shown a disparity in how they manage metadata. We are evaluating multiple ebook publishers’ data in the KB based on the availability of call numbers and subject headings while looking at resource usage. Exploring ways to improve access by including call numbers and subject headings and discovering the larger problem.

Gardner-Webb Officials Announce Speaker For 2023 Commencement Ceremony, Office Of University Communications

Gardner-Webb NewsCenter Archive

Business executive and former N.C. Secretary of Commerce, Sharon Decker, will be the guest speaker for the Spring 2023 Commencement program at Gardner-Webb University. The traditional ceremony will take place on Thursday, May 4, at 7 p.m. in Spangler Stadium.

Ud In The News March 3-10, University Of Dayton

News Releases

The Conversation, The National Desk, Politico and The Circuit News are among the national outlets seeking UD faculty expertise. Regional and local media highlighted several faculty and initiatives, including the NCAA First Four.

Comparing Five Equations To Calculate Estimated Glomerular Filtration Rate To Predict Acute Kidney Injury Following Total Joint Arthroplasty., Kevin L Mekkawy, Yash P Chaudhry, Sandesh S Rao, Micheal Raad, Raj M Amin, Harpal S Khanuja

Orthopedic Surgery Resident Research

BACKGROUND: Acute kidney injury (AKI) following total joint arthroplasty (TJA) is associated with increased morbidity and mortality. Estimated glomerular filtration rate (eGFR) is used as an indicator of renal function. The purpose of this study was (1) to assess each of the five equations that are used in calculating eGFR, and (2) to evaluate which equation may best predict AKI in patients following TJA.

METHODS: The National Surgical Quality Improvement Program (NSQIP) was queried for all 497,261 cases of TJA performed from 2012 to 2019 with complete data. The Modification of Diet in Renal Disease (MDRD) II, re-expressed MDRD II, …

Finite Element Modeling Of Meniscal Tears Using Continuum Damage Mechanics And Digital Image Correlation, Derek Q. Nesbitt, Dylan E. Burruel, Bradley S. Henderson, Trevor J. Lujan

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Meniscal tears are a common, painful, and debilitating knee injury with limited treatment options. Computational models that predict meniscal tears may help advance injury prevention and repair, but first these models must be validated using experimental data. Here we simulated meniscal tears with finite element analysis using continuum damage mechanics (CDM) in a transversely isotropic hyperelastic material. Finite element models were built to recreate the coupon geometry and loading conditions of forty uniaxial tensile experiments of human meniscus that were pulled to failure either parallel or perpendicular to the preferred fiber orientation. Two damage criteria were evaluated for all experiments: …