Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 255061 - 255090 of 1795476

Full-Text Articles in Entire DC Network

Personal Perspective: Violence Against Healthcare Workers In Us Eds, Peter W. Sweetser, James P. Phillips Mar 2023

Personal Perspective: Violence Against Healthcare Workers In Us Eds, Peter W. Sweetser, James P. Phillips

URGENT Matters

No abstract provided.


Violence Against Women, Christine M. Chinkin, Lisa Gormley Mar 2023

Violence Against Women, Christine M. Chinkin, Lisa Gormley

Book Chapters

There is no provision in either the Declaration {DEDAW) or Convention on the Elimination of All Forms of Discrimination against Women (the Convention) that explicitly addresses violence against women. This contrasts with the International Convention on the Elimination of All Forms of Racial Discrimination (ICERD) Article 4(a) which requires States parties to declare as 'an offence punishable by law [ ... ] all acts of violence [ ... ] against any race or group of persons of another colour or ethnic origin'. Instead, States parties' obligations with respect to the elimination of violence against: women have been developed by a …


How To Have A Great Family Spring Break Staycation, Staff Mar 2023

How To Have A Great Family Spring Break Staycation, Staff

Browse All News

No abstract provided.


College Of Liberal Arts Faculty Bylaws - Amended 3/15/23, College Of Liberal Arts Faculty, Rollins College Mar 2023

College Of Liberal Arts Faculty Bylaws - Amended 3/15/23, College Of Liberal Arts Faculty, Rollins College

College of Liberal Arts Bylaws

No abstract provided.


The Development, Implementation And Early Learnings Of A Training Program To Advance Interest In Behavioral Research Careers Among Undergraduate Bipoc Students Majoring In Psychology., Michelle R. Lent, Denise Gaither-Hardy, Kevin E Favor, Diana Harris, Travis A Cos, Conor Millard, Zatio Kone, Ashley Van Riper, Karen L Dugosh Mar 2023

The Development, Implementation And Early Learnings Of A Training Program To Advance Interest In Behavioral Research Careers Among Undergraduate Bipoc Students Majoring In Psychology., Michelle R. Lent, Denise Gaither-Hardy, Kevin E Favor, Diana Harris, Travis A Cos, Conor Millard, Zatio Kone, Ashley Van Riper, Karen L Dugosh

PCOM Scholarly Works

OBJECTIVES: Black, indigenous and people of color (BIPOC) remain underrepresented in research occupations. This report discusses a collaboration to train undergraduate BIPOC students in clinical research between a public health institute, two medical schools, and a historically Black College or University (HBCU). This nine-month program trained BIPOC undergraduates in research methodology, psychology, and addiction science, and immersed trainees in real-world research. The program included didactic seminars, experiential activities, and a mentored research project culminating in a poster and oral presentation.

METHODS: Key learnings, program satisfaction survey results, and preliminary outcomes from the first three program cohorts (N = 6 students) …


Remote Medical Diagnosis Via Infrared Thermography And Augmented Reality, Frederick M. Selkey Mar 2023

Remote Medical Diagnosis Via Infrared Thermography And Augmented Reality, Frederick M. Selkey

USF Tampa Graduate Theses and Dissertations

Fast, accurate, and non-invasive diagnostic techniques are required by the medical industry to increase the success of medical treatments and enhance the quality of patient care. Medical IRT has been demonstrated reasonably effective at diagnosing and monitoring several physiological conditions. Diversities in the human body, physical and psychological condition, measurement equipment, and environment all influence the sensitive readings obtained by passive IR measurement devices. New standards for medical IRT and fever screening have been demonstrated effective, but there is limited adherence to the guidelines [36]. Absolute temperature readings require regular calibration checks and can easily be thrown off by noise. …


Signed, Sealed, & Reconsidered: An Investigation Into Former President Trump’S Signing Statements Between 2019 And 2020 (2023), Isabelle Canaan Mar 2023

Signed, Sealed, & Reconsidered: An Investigation Into Former President Trump’S Signing Statements Between 2019 And 2020 (2023), Isabelle Canaan

UIC Law Review

No abstract provided.


Transcranial Magnetic Stimulation To The Angular Gyrus Modulates The Temporal Dynamics Of The Hippocampus And Entorhinal Cortex, Gillian Coughlan, Nichole R. Bouffard, Ali Golestani, Preston P. Thakral, Daniel L. Schacter, Cheryl Grady, Morris Moscovitch Mar 2023

Transcranial Magnetic Stimulation To The Angular Gyrus Modulates The Temporal Dynamics Of The Hippocampus And Entorhinal Cortex, Gillian Coughlan, Nichole R. Bouffard, Ali Golestani, Preston P. Thakral, Daniel L. Schacter, Cheryl Grady, Morris Moscovitch

Psychology: Faculty Publications

Transcranial magnetic stimulation (TMS) delivered to the angular gyrus (AG) affects hippocampal function and associated behaviors (Thakral PP, Madore KP, Kalinowski SE, Schacter DL. Modulation of hippocampal brain networks produces changes in episodic simulation and divergent thinking. 2020a. Proc Natl Acad Sci U S A. 117:12729-12740). Here, we examine if functional magnetic resonance imaging (fMRI)-guided TMS disrupts the gradient organization of temporal signal properties, known as the temporal organization, in the hippocampus (HPC) and entorhinal cortex (ERC). For each of 2 TMS sessions, TMS was applied to either a control site (vertex) or to a left AG target region (N …


Short-Term Changes In Ultrasound Tomography Measures Of Breast Density And Treatment-Associated Endocrine Symptoms After Tamoxifen Therapy, Cody Ramin, Ruth M. Pfeiffer, Sharon Fan, Maeve Mullooly, Roni T. Falk, Kristine Jones, Neil E. Caporaso, Lisa Bey-Knight, Mark A. Sak, Michael S. Simon, David H. Gorski, Haythem Y. Ali, Peter Littrup, Neb Duric, Mark E. Sherman, Gretchen L. Gierach Mar 2023

Short-Term Changes In Ultrasound Tomography Measures Of Breast Density And Treatment-Associated Endocrine Symptoms After Tamoxifen Therapy, Cody Ramin, Ruth M. Pfeiffer, Sharon Fan, Maeve Mullooly, Roni T. Falk, Kristine Jones, Neil E. Caporaso, Lisa Bey-Knight, Mark A. Sak, Michael S. Simon, David H. Gorski, Haythem Y. Ali, Peter Littrup, Neb Duric, Mark E. Sherman, Gretchen L. Gierach

Hematology/Oncology Articles

Although breast density decline with tamoxifen therapy is associated with greater therapeutic benefit, limited data suggest that endocrine symptoms may also be associated with improved breast cancer outcomes. However, it is unknown whether endocrine symptoms are associated with reductions in breast density after tamoxifen initiation. We evaluated treatment-associated endocrine symptoms and breast density change among 74 women prescribed tamoxifen in a 12-month longitudinal study. Treatment-associated endocrine symptoms and sound speed measures of breast density, assessed via novel whole breast ultrasound tomography (m/s), were ascertained before tamoxifen (T0) and at 1-3 (T1), 4-6 (T2), and 12 months (T3) after initiation. CYP2D6 …


Nationwide Results Of Microorganism Antigen Testing As A Component Of Preoperative Synovial Fluid Analysis., Krista O'Shaughnessey Toler, Pearl Ravindra Paranjape, Alex Mclaren, Brett Levine, Alvin Ong, Carl Deirmengian Mar 2023

Nationwide Results Of Microorganism Antigen Testing As A Component Of Preoperative Synovial Fluid Analysis., Krista O'Shaughnessey Toler, Pearl Ravindra Paranjape, Alex Mclaren, Brett Levine, Alvin Ong, Carl Deirmengian

Rothman Institute Papers

BACKGROUND: Antigen immunoassays to detect synovial fluid (SF) microorganisms have recently been made available for clinical use. The purpose of this study was to determine the sensitivity and specificity of an SF microorganism antigen immunoassay detection (MID) panel, evaluate the panel's capability to detect microorganisms in the setting of culture-negative periprosthetic joint infection (PJI), and determine diagnostic predictive values of the MID panel for PJI.

METHODS: This study included 67,441 SF samples obtained from a hip or knee arthroplasty, from 2,365 institutions across the United States, submitted to 1 laboratory for diagnostic testing. All data were prospectively compiled and then …


Grove Scholars Profile: Brittney Banks, Brittney Banks, Jared Redding Mar 2023

Grove Scholars Profile: Brittney Banks, Brittney Banks, Jared Redding

Grove Scholars

No abstract provided.


Grove Scholars Profile: Chandler Tolbert, Chandler Tolbert, Hayden Wiggs Mar 2023

Grove Scholars Profile: Chandler Tolbert, Chandler Tolbert, Hayden Wiggs

Grove Scholars

No abstract provided.


Why Theorizing And Measuring Shared Experience In Descriptive Representation Is “A Mess Worth Making”, Christina Xydias Mar 2023

Why Theorizing And Measuring Shared Experience In Descriptive Representation Is “A Mess Worth Making”, Christina Xydias

Faculty Journal Articles

Jane Mansbridge’s (1999) “contingent ‘yes’” amplified a chorus of voices discussing the substantive and symbolic functions of historically marginalized groups’ presence in political office. In her essay, Mansbridge points to contexts of mistrust and uncrystallized interests as domains where presence enhances “adequate communication” and “innovative thinking” for these social groups (628). In this and many other accounts, the linchpin between descriptive and substantive representation for these functions is group members’ shared experiences, alternatively framed as the perspectives informed by those experiences. Shared experiences cannot and do not produce identical effects (they are filtered through many lenses), but they are widely …


Medication Adherence Via A Smartphone Application, Robert B. Marsh Mar 2023

Medication Adherence Via A Smartphone Application, Robert B. Marsh

Seton Hall University Dissertations and Theses (ETDs)

Medication adherence among the mentally ill is critical.


Preclinical Perspectives On The Mechanisms Underlying The Therapeutic Actions Of Psilocybin In Psychiatric Disorders, Andreas B. Wulff, Charles D. Nichols, Scott M. Thompson Mar 2023

Preclinical Perspectives On The Mechanisms Underlying The Therapeutic Actions Of Psilocybin In Psychiatric Disorders, Andreas B. Wulff, Charles D. Nichols, Scott M. Thompson

School of Medicine Faculty Publications

Psychedelic compounds have shown extraordinary potential in treating a wide range of neuropsychiatric disorders. Psilocybin, for example, has now been shown in several clinical trials to induce a rapid (within days) and persistent (3–12 months) improvement in human treatment-resistant depression and other neuropsychiatric conditions. Here we review the preclinical models and experimental approaches that have been used to study the neurobiological actions of psychedelic drugs. We further summarize the insights these studies have provided into the possible mechanisms underlying the induction of their therapeutic actions, including the receptors to which psychedelics bind and the second messenger signaling cascades that they …


Delayed Thoracodorsal Artery Perforator Free Flap For Calcaneal Degloving Injury Reconstruction, Mallorie L. Huff, Ahmed M. Mansour, Mamtha S. Raj, Robert J. Allen, Sean J. Wallace Mar 2023

Delayed Thoracodorsal Artery Perforator Free Flap For Calcaneal Degloving Injury Reconstruction, Mallorie L. Huff, Ahmed M. Mansour, Mamtha S. Raj, Robert J. Allen, Sean J. Wallace

School of Medicine Faculty Publications

The thoracodorsal artery perforator (TDAP) flap has a long vascular pedicle that is ideal for lower extremity reconstruction, but it generally relies on the presence of a dominant septocutaneous perforator vessel. Surgical delay optimizes flap survival by creating relative ischemia to augment perforator vessels. In this report, we describe the use of a delayed free TDAP flap in the setting of an absent dominant perforator vessel for the reconstruction of a calcaneal degloving injury. A 22-year-old actively smoking patient with a body mass index of 33.5 presented with a nonhealing left heel wound with overlying necrotic changes after traumatic degloving …


Doing Death Work: A Mixed Method Examination Of Imprinted Events And Behavioral Responses Of Medical Examiner's Office Employees, Elizabeth L. Gilmore, Kevin Buckler Mar 2023

Doing Death Work: A Mixed Method Examination Of Imprinted Events And Behavioral Responses Of Medical Examiner's Office Employees, Elizabeth L. Gilmore, Kevin Buckler

Qualitative Criminology (QC)

"This study provides a qualitative and quantitative data analysis from interviews of current and former employees of medical examiner offices. These employees’ current and former positions required that they arrive at scenes of natural, accidental, suicidal, undetermined, and homicidal deaths, document and retrieve the decedent(s), and assist in eviscerating the remains to aid forensic pathologists during autopsy procedures. The authors interviewed 14 current or past employees of different medical examiner offices to understand what they liked and disliked about this curious profession and aimed to understand professional struggles. Additionally, study participants answered questions about imprinted events, how they and colleagues …


Editorial, Kevin Buckler Mar 2023

Editorial, Kevin Buckler

Qualitative Criminology (QC)

This issue contains five articles that utilize various qualitative and mixed methods.


“Title Ix Isn’T For You, It’S For The University”: Sexual Violence Survivors’ Experiences Of Institutional Betrayal In Title Ix Investigations, Katherine Lorenz, Rebecca Hayes, Cathrine Jacobsen Mar 2023

“Title Ix Isn’T For You, It’S For The University”: Sexual Violence Survivors’ Experiences Of Institutional Betrayal In Title Ix Investigations, Katherine Lorenz, Rebecca Hayes, Cathrine Jacobsen

Qualitative Criminology (QC)

Institutional betrayal occurs when an institution fails to appropriately respond to harm experienced by a member of the institution, such as by failing to act or by mishandling cases. The concept has been applied to higher education institution’s (HEI’s) response to students who experience sexual violence, particularly Title IX investigations, showing that institutional betrayal is common among student survivors. Yet, to our knowledge, institutional betrayal in HEI Title IX investigations has not been qualitatively explored. We conducted interviews of graduate and undergraduate student sexual violence survivors (n=21) who participated in a Title IX investigation at a U.S. HEI to understand …


Treating Criminal Justice-Involved Serious Mental Illness (Smi) Clients In The Community, Brittany Hood Mar 2023

Treating Criminal Justice-Involved Serious Mental Illness (Smi) Clients In The Community, Brittany Hood

Qualitative Criminology (QC)

With criminal justice-involved individuals with serious mental illness (SMI) at an all-time high in the criminal justice system, research on community mental health centers (CMHCs) demonstrates a lack of treatment for justice-involved persons. Scholars have argued that providing appropriate treatment to criminal justice-involved individuals with SMI could alleviate symptoms. Therefore improving the effectiveness of mental health treatment to reduce recidivism in this population is paramount. The current study used a qualitative approach to examine how community service providers perceived organizational-level variables and legal constraints to influence treatment decisions for justice-involved individuals with SMI. Findings suggest three critical implications for policy …


Ttr Amyloidosis: Current State Of Affairs And Promise For The Future, Yevgeniy Brailovsky, Indranee Rajapreyar, Rene Alvarez Mar 2023

Ttr Amyloidosis: Current State Of Affairs And Promise For The Future, Yevgeniy Brailovsky, Indranee Rajapreyar, Rene Alvarez

Division of Cardiology Faculty Papers

No abstract provided.


Nebraska Farmland Values And Cash Rental Rates In 2023, Jim Jansen, Jeffrey Stokes Mar 2023

Nebraska Farmland Values And Cash Rental Rates In 2023, Jim Jansen, Jeffrey Stokes

Cornhusker Economics

The market value of agricultural land in Nebraska increased by 14% over the prior year to an average of US $3,835 per acre, according to the 2023 Nebraska Farm Real Estate Market Survey. This marks the second-largest increase in the market value of agricultural land in Nebraska since 2014 and the highest non-inflation-adjusted state-wide land value in the 45-year history of the survey.

The University of Nebraska-Lincoln’s Department of Agricultural Economics annually surveys land industry professionals across Nebraska, including appraisers, farm and ranch managers, agricultural bankers, and related industry professionals. Results from the survey are divided by land class and …


Midweek Memo, Georgia Southern University Mar 2023

Midweek Memo, Georgia Southern University

Midweek Memo

Applaud

Remember

Share

Experience

You May Have Heard


Changes In Clinical Markers Observed From Pharmacist-Managed Cardiovascular Risk Reduction Clinics In Federally Qualified Health Centers: A Retrospective Cohort Study, Jasmine Gonzalvo, Ashley H. Meredith, Sonak Pastakia, Michael Peters, Madilyn Eberle, Andrew N. Schmelz, Lauren Pence, Jessica S. Triboletti, Todd A. Walroth Mar 2023

Changes In Clinical Markers Observed From Pharmacist-Managed Cardiovascular Risk Reduction Clinics In Federally Qualified Health Centers: A Retrospective Cohort Study, Jasmine Gonzalvo, Ashley H. Meredith, Sonak Pastakia, Michael Peters, Madilyn Eberle, Andrew N. Schmelz, Lauren Pence, Jessica S. Triboletti, Todd A. Walroth

Department of Pharmacy Practice Faculty Publications

Background

Reductions in hemoglobin A1c (HbA1C) have been associated with improved cardiovascular outcomes and savings in medical expenditures. One public health approach has involved pharmacists within primary care settings. The objective was to assess change in HbA1C from baseline after 3–5 months of follow up in pharmacist-managed cardiovascular risk reduction (CVRR) clinics.

Methods

This retrospective cohort chart review occurred in eight pharmacist-managed CVRR federally qualified health clinics (FQHC) in Indiana, United States. Data were collected from patients seen by a CVRR pharmacist within the timeframe of January 1, 2015 through February 28, 2020. Data collected include: demographic characteristics and clinical …


Elevating The Silicon Slopes, Joseph Evans Mar 2023

Elevating The Silicon Slopes, Joseph Evans

Undergraduate Honors Theses

From Utah’s humble beginnings in agriculture and mining, Utah has become an economic powerhouse in the United States, largely due to the rise of Silicon Slopes. Despite the successes of Silicon Slopes, there are still significant shortcomings related to diversity and inclusion in Silicon Slopes that must be remediated if it intends to achieve its economic aspirations and ensure its economic benefits flow to people of all types and backgrounds. This work outlines both the rise of Silicon Slopes as well as existing and potential private- and state-ordered solutions that may be implemented to overcome Silicon Slopes’ existing diversity and …


High Prevalence Of Cardiometabolic Risk Factors Amongst Young Adults In The United Arab Emirates: The Uae Healthy Future Study, Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E. Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H. Al-Rifai, Scott Sherman, Syed M. Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed Mar 2023

High Prevalence Of Cardiometabolic Risk Factors Amongst Young Adults In The United Arab Emirates: The Uae Healthy Future Study, Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E. Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H. Al-Rifai, Scott Sherman, Syed M. Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed

All Works

BackgroundCardiovascular disease (CVD) is the leading cause of death in the world. In the United Arab Emirates (UAE), it accounts for 40% of mortality. CVD is caused by multiple cardiometabolic risk factors (CRFs) including obesity, dysglycemia, dyslipidemia, hypertension and central obesity. However, there are limited studies focusing on the CVD risk burden among young Emirati adults. This study investigates the burden of CRFs in a sample of young Emiratis, and estimates the distribution in relation to sociodemographic and behavioral determinants.MethodsData was used from the baseline data of the UAE Healthy Future Study volunteers. The study participants were aged 18 to …


The Role Of Nod-Like Receptors In Innate Immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius Mar 2023

The Role Of Nod-Like Receptors In Innate Immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger. Research into the family of NOD-like receptors (NLRs) has blossomed over the past two decades, with much being learned about the ligands and conditions that stimulate the NLRs and the outcomes of NLR activation in cells and animals. The NLRs play key roles in diverse functions, ranging from transcription of MHC molecules to initiation of inflammation. Some NLRs are activated directly by their ligands, while other ligands …


Chronic Administration Of Melatonin: Physiological And Clinical Considerations, Donald Givler, Amy Givler, Patrick M. Luther, Danielle M. Wenger, Shahab Ahmadzadeh, Sahar Shekoohi, Amber N. Edinoff, Bradley K. Dorius, Carlo Jean Baptiste, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye Mar 2023

Chronic Administration Of Melatonin: Physiological And Clinical Considerations, Donald Givler, Amy Givler, Patrick M. Luther, Danielle M. Wenger, Shahab Ahmadzadeh, Sahar Shekoohi, Amber N. Edinoff, Bradley K. Dorius, Carlo Jean Baptiste, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye

Pacific Faculty Work

Background: Exogenous melatonin is commonly used to treat insomnia, other sleep problems, and numerous medical illnesses, including Alzheimer’s disease, autism spectrum disorder, and mild cognitive impairment in adults and children. There is evolving information regarding issues with the use of chronic melatonin. Methods: The present investigation was a narrative review. Results: Melatonin usage has risen dramatically in recent years. Many countries only allow melatonin prescriptions. In the United States (U.S.), it is classified as a dietary supplement accessible over the counter and can be derived from animals, microorganisms, or, most commonly, made synthetically. No regulatory agency oversees its manufacturing or …


Fresh Produce As A Potential Vector And Reservoir For Human Bacterial Pathogens: Revealing The Ambiguity Of Interaction And Transmission, Ahmed Esmael, Rashad R. Al-Hindi, Raed S. Albiheyri, Mona G. Alharbi, Amani A. R. Filimban, Mazen S. Alseghayer, Abdulaziz M. Almaneea, Meshari Ahmed Alhadlaq, Jumaa Ayubu, Addisu D. Teklemariam Mar 2023

Fresh Produce As A Potential Vector And Reservoir For Human Bacterial Pathogens: Revealing The Ambiguity Of Interaction And Transmission, Ahmed Esmael, Rashad R. Al-Hindi, Raed S. Albiheyri, Mona G. Alharbi, Amani A. R. Filimban, Mazen S. Alseghayer, Abdulaziz M. Almaneea, Meshari Ahmed Alhadlaq, Jumaa Ayubu, Addisu D. Teklemariam

Nebraska Center for Virology: Faculty Publications

The consumer demand for fresh produce (vegetables and fruits) has considerably increased since the 1980s for more nutritious foods and healthier life practices, particularly in developed countries. Currently, several foodborne outbreaks have been linked to fresh produce. The global rise in fresh produce associated with human infections may be due to the use of wastewater or any contaminated water for the cultivation of fruits and vegetables, the firm attachment of the foodborne pathogens on the plant surface, and the internalization of these agents deep inside the tissue of the plant, poor disinfection practices and human consumption of raw fresh produce. …


The Pathogenesis Of Covid-19: Hypercoagulation And D-Dimer In Thrombotic Complications, Leonid Dubey, Halyna Lytvyn, Olha Dorosh, Nataliya Dubey, Olena Kozlova, Michal Pruc, Nina Kubikowska, Lukasz Szarpak, Kavita Batra, Francesco Chirico, Gabriella Nucera, Svitlana Doan, Uljana Shevtsiv Mar 2023

The Pathogenesis Of Covid-19: Hypercoagulation And D-Dimer In Thrombotic Complications, Leonid Dubey, Halyna Lytvyn, Olha Dorosh, Nataliya Dubey, Olena Kozlova, Michal Pruc, Nina Kubikowska, Lukasz Szarpak, Kavita Batra, Francesco Chirico, Gabriella Nucera, Svitlana Doan, Uljana Shevtsiv

School of Medicine Faculty Research

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused a new coronavirus disease (COVID-19), which is highly contagious and its pathogenesis has not been fully elucidated. In COVID-19, the inflammation and blood coagulation systems are excessively activated. SARS-CoV- 2 damages endothelial cells and pneumocytes, which leads to disruption of hemostasis in SARS. Thromboembolism is the main cause of mortality in patients with COVID-19. Clots, including pulmonary embolism (PE) and deep vein thrombosis (DVT), ranging from minor to fatal complications of the SARS-CoV-2 infection are known. Individuals with pre-existing diseases are more susceptible to the development of blood clots and poor outcomes. …