Digital Commons Network^™

Network Pharmacology And Bioinformatics Analysis Of The Potential Mechanism Of Sesame Oil In Treating Insomnia, La Mu, Ze Wengyongzhong, Sang Jikangzhuo, Hua Erjiang, Jiang Yongsilang

Food and Machinery

[Objective] To explore the molecular mechanism of sesame oil in treating insomnia by network pharmacology, bioinformatics, and molecular docking methods. [Methods] Sesame oil targets are screened by TCMSP and Herb databases, while insomnia-related targets are searched in GeneCard, ETCM, DrugBank database, and GSE 189993 data set. Then, the intersection is found to obtain the common targets. The protein interaction network is constructed by the String software for gene ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. The binding abilities of the active ingredients and the targets are evaluated by molecular docking on the AutoDock …

Intelligent Detection Method For Foreign Objects In Packaged Foods Based On Improved Yolov 13 And X-Ray, Guo Dechao, Liu Zizhi, Zhang Hao, Zhao Qiang

Food and Machinery

[Objective] To address problems in X-ray-based foreign object detection in packaged foods, including low accuracy caused by the high proportion of low-frequency features in images and small grayscale differences between foreign objects and the background, as well as the loss of micro foreign object features, an improved intelligent detection scheme is proposed to overcome the inability of traditional detection methods to meet the real-time and reliability requirements of automated production lines. [Methods] Based on the intelligent detection system for foreign objects in packaged foods, this study proposes an intelligent detection method for foreign objects in packaged foods integrating an improved …

Effects Of Electron Beam Irradiation On Physicochemical Properties And Edible Quality Of Guangxi Fragrant Rice, Chen Xiuxia, Zhang Bin

Food and Machinery

[Objective] To investigate the effect of electron beam irradiation (EBI) on the storage quality of high-moisture Guangxi fragrant rice. [Methods] High-moisture fragrant rice is subjected to electron beam irradiation in varying doses (1 to 5 kGy). Then, changes in its physicochemical properties and edible quality are studied during storage. [Results] After low-dose EBI treatment, no significant change is observed in the moisture content of the fragrant rice. During storage, the growth rates of lipase activity and fatty acid value decrease in the irradiated fragrant rice, with inhibited microbial proliferation. Compared with non-irradiated fragrant rice, the irradiated fragrant rice exhibits slowly …

Mechanisms Of Licochalcone A In Inhibiting Tumor Growth Via Lncrna-Cdc 42bpa-Ampk/Mtor Axis, Shi Zhan, Yao Meicun, Shi Xianyong, Tan Panpan

Food and Machinery

[Objective] To investigate the molecular mechanism by which licochalcone A inhibits colorectal cancer growth through regulation of the AMPK/mTOR signaling axis via long non-coding RNAs (LncRNAs). [Methods] Human colorectal cancer HCT 116 cells and a nude mouse subcutaneous xenograft model were used. Cell proliferation was assessed by CCK-8 and EdU assays, and cell migration was evaluated by wound healing and Transwell assays. Quantitative PCR (qPCR) was employed to detect the expression levels of proliferation- and migration-related markers, and Western blotting was performed to analyze the expression of proteins related to the AMPK/mTOR pathway. Differential expressed LncRNAs in HCT 116 cells …

Extraction And Analysis Of Structural Characterization And Antioxidant Activity Of Polysaccharides From Xiaobai Apricots, Chen Lin, Abudureheman Buhailiqiemu, Jiang Luxi, Tang Rui, Zhang Jianlin, Gao Zhihui

Food and Machinery

[Objective] To explore the extraction process and structural characterization of polysaccharides from Xiaobai apricots. [Methods] Xinjiang Xiaobai apricots are used as raw materials. The extraction process of Xiaobai apricot polysaccharides is optimized using response surface methodology (RSM). The structural properties of the polysaccharides are characterized by high-performance liquid chromatography (HPLC), Fourier transform infrared spectroscopy (FT-IR), differential refractometry, and scanning electron microscopy (SEM). The antioxidant activity is evaluated by measuring the scavenging abilities of DPPH radicals, ABTS+ radicals, and hydroxyl radicals. [Results] The optimal extraction conditions are determined as a solid-to-liquid ratio of 1∶40 (g/mL), extraction time of 6 h, and …

Application Of Stable High Internal Phase Emulsions Based On Wheat Bran Water Extract In Cakes, Zhang Jing, Wang Lifeng, Xiong Wenfei, Ye Xinwei

Food and Machinery

[Objective] To investigate the application of high internal phase emulsions (HIPEs) stabilized by wheat bran water extract as a butter substitute in cakes. [Methods] Cakes were prepared by substituting butter with HIPEs stabilized by wheat bran water extract at different ratios, with a pure soybean oil group used as the control. The viscosity, relative density, and microstructure of the cake batter were systematically measured, and the textural properties, moisture distribution, color, X-ray diffraction (XRD) patterns, and flavor profiles of the cakes were comprehensively analyzed. [Results] With increasing substitution ratios of HIPEs, the a* value of the cakes increased while the …

Research And Application Progress Of Functional Raw Materials For Blood Glucose-Lowering Foods, Wang Zhenwu, Chen Xiaoqing, Ding Ning, Chen Yaling, Chen Xumeng, Xia Xinbin

Food and Machinery

Type 2 diabetes mellitus involves a variety of pathological mechanisms. Chinese medicine treatment often employs the Chinese medicinal materials such as Coptidis Rhizoma and Astragali Radix with both medicinal and edible values to achieve multi-target synergistic blood glucose-lowering effects. Using these materials as the main ingredients to develop functional foods such as meal replacements, snacks, and drinks for lowering blood glucose becomes an innovative strategy for managing type 2 diabetes mellitus. This paper systematically reviews five blood glucose-lowering mechanisms of functional foods and drug ingredients, including protection of islet β-cells, enhancement of insulin sensitivity, inhibition of α-amylase, regulation of lipid …

Properties And Research Progress Of Deacetylated Konjac Glucomannan In Food Applications, Liu Kai, Zhang Ling, Wang Jing

Food and Machinery

Konjac glucomannan (KGM) is a natural soluble dietary fiber that is safe, biodegradable, and edible, with wide application in food and biomedicine. However, due to low plasticity and stability, KGM usually requires blending, physical, and chemical modification for production. Currently, deacetylated konjac glucan (DKGM) is used in food mainly as a food additive, food preservative, and health food. This review elucidates the KGM property changes before and after different deacetylation degrees, as well as the application progress and research status of DKGM in the food industry, with prospects for its development trends.

Construction Of Sulfur Dioxide Fluorescent Probe And Its Application Progress In Food, Pharmaceuticals, And Biological Systems, Xiao Zhongshan, Yang Guojing, Gao Ha, Wang Tianlin

Food and Machinery

Sulfur dioxide (SO2) and its derivatives (SO2-3 and HSO-3) are ubiquitous in the environment and our daily life, closely related to human life activities. As an important additive, SO2 serves functions including bleaching, sterilization, anti-corrosion, color protection, antioxidant, and others during the processing and storage of food and pharmaceuticals. Additionally, SO2 can regulate the antioxidant enzyme system in human cells, increasing resistance against oxidative stress damage. However, excessive SO2 in the human body can strongly stimulate the digestive tract, causing nausea, vomiting, and abdominal pain, and may trigger allergic reactions including asthma and headaches. Furthermore, long-term intake can damage digestive …

Using Machine Learning Algorithms To Clarify Relationships Between Soil Properties And Lead Stomach Bioaccessibility, Shehan Wijesinghe, Dibyendu Sarkar, Hadeer Saleh, Khalid Mustafa, Smitha Rao, Rupali Datta

Michigan Tech Publications

Featured Application: This paper has important applications in environmental health risk assessment and urban soil remediation planning. By demonstrating how machine learning can predict lead bioaccessibility in lead paint-contaminated soil, the study provides a scalable, cost-effective alternative to laboratory-based extraction methods. Such models could support rapid screening of contaminated sites, helping prioritize high-risk areas for intervention and allocate remediation resources more efficiently. This model is expected to advance data-driven decision-making for managing lead-contaminated soils and protect vulnerable urban populations from exposure. Lead contamination in urban soils, primarily from deteriorating lead-based paint, poses a significant health risk in the United States. …

Engaging Rural Adults With Type 2 Diabetes In Adaptation Of A Physical Activity Intervention For A Mobile App, Chelsea Howland

Sigma Foundation for Nursing Research Grant Reports

The purpose of this study was to 1) adapt a physical activity self-management intervention for a mobile app platform and 2) explore preferences for and understanding of graphically presented physical activity data in individuals aged 40 and older with T2D.

Aim 1: To engage end-users in adapting a physical activity self-management intervention for a mobile app delivery platform and explore acceptance.

Aim 2: To describe preferences for and understanding of graphically presented physical activity data.

Personal Healthcare Networks Of Transgender And Gender-Diverse Adults After Gender-Affirming Surgery, Tyler Gaedecke

Sigma Foundation for Nursing Research Grant Reports

The purpose of this study was to investigate access to healthcare among transgender and gender-diverse (TGD) individuals after gender-affirming surgery by using social network analysis to describe their “personal healthcare networks” of healthcare professionals. Our first aim was to characterize the content, function, and structure of the personal healthcare networks of TGD adults after gender-affirming surgery (N = 130) and examine associations with self-rated physical and mental health. Our second aim was to qualitatively explore TGD adults’ experiences of constructing, accessing, and engaging with those personal healthcare networks after surgery (N = 24).

Opium Of The Masses: An Analysis Of Archeobotanical Research In The City Of Tábor, Czechia And How It Potentially Influenced Forms Of Radical Hussism, Sasha Gladding

Undergraduate University Honors Capstones

Opium of the Masses performs in depth analysis of the Hussite Wars–a time period lasting from 1419 to 1436, Jan Hus, Hussite factionalism, and archeobotany. This analysis proposes that there are numerous possible contributing factors to the development of the radical Hussite teachings and ways of life. The instability of the Catholic hierarchy and the dissenting teachings of Jan Hus also likely were contributors to the development of the unique sociopolitical and spiritual practices of the radical Hussites. It is also possible that the Hussite factions residing in the Czech (then Bohemian) town of Tábor utilized opium as an entheogen …

Patient-Provider Communication Among Deaf English Users: Disparities And Implications For Cancer Screening, Ciara Luttrell

Undergraduate University Honors Capstones

Early detection is one of medicine's powerful tools; routine cancer screenings can help diagnose cancer early and enable immediate treatment. Cancer screening and prevention efforts have accounted for 4.75 million (80%) cancer deaths averted between 1975 and 2020 for five major cancer types (NIH, 2025). Nevertheless, this powerful tool is not shared equally. Many deaf adults who use English still experience barriers and disparities. Accordingly, the purpose of this study is to investigate how deaf English-using individuals in the United States interact with their healthcare providers and whether these interactions are associated with cancer screening interest among these populations. The …

A Platform For Acquiring And Classifying Low-Noise Electrocardiogram Signals For Applications In Cardiovascular Monitoring, Begmamat Berdimurodovich Dushanov, Narzullo Mamatov Dr.

Technical science and innovation

The early screening and continuous monitoring of cardiovascular diseases need effective acquisition and smart processing of electrocardiogram (ECG) signals. In this article, we introduce a compact platform designed for the acquisition of low-noise ECG signals and classification of the signals using a one-dimensional convolutional neural network (1D-CNN). Our compact platform consists of a low-noise analog front-end (AFE), including an instrumentation amplifier and a chain of analog filters, along with a data acquisition component designed to ensure effective suppression of baseline wander and high frequencies. Our compact platform consumes a low amount of power and can therefore be used for continuous …

April 3, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Head Shot, Joanmarie Ilaria Davoli

Mercer Law Review

The prohibition of cruel and unusual punishment in the Eighth Amendment of the U.S. Constitution requires that execution methods avoid “superadding pain.” The U.S. Supreme Court has held that the imposition of a death sentence should include no additional pain beyond that needed to kill. That means, for example, that while pain may be inherent in the method of killing, torture is prohibited. As concerns about the pain involved in lethal injections has increased, states have begun executions by shooting inmates in the heart and by suffocation through gas mask. These methods have been used despite evidence that they superadd …

Still Uncertain After All Of These Years: Constitutional Rights Of Guantanamo Detainees Tried By Military Commission, Michael D. Ross

Mercer Law Review

This article explores whether Guantanamo detainees are entitled to constitutional protections at military commission trials. In 2006, Congress passed the Military Commissions Act (“MCA”). Its goal was to establish a fair system to try foreign detainees accused of war crimes. The ensuing nineteen years have revealed that the system needs reform. The most important cases, such as the 9/11 and U.S.S. Cole prosecutions, are still bogged down in pre-trial litigation that has lasted over a decade. But before policy makers consider reforms, they should know what constitutional protections apply at a military commission. Federal courts have not answered that question. …

Deliberately Silenced, Rachel Kincaid

Mercer Law Review

The Prison Litigation Reform Act is celebrating its 30^th birthday this year. It was designed to make it harder for incarcerated people to file lawsuits challenging the constitutionality of their conditions of confinement and to restrict their remedies even when they do so successfully. It has been wildly effective at achieving those objectives. It has also propped up mass incarceration and facilitated the persistence of dismal conditions of confinement in carceral facilities in the United States.

The PLRA’s exhaustion requirement—arguably its most damaging provision—silences carceral voices without regard for the merit of their complaints. It does so by mandating …

Occ's Plan

Catholic Dioceses in Bankruptcy

No abstract provided.

Medicare Part D Formulary Coverage Of Disease-Modifying Therapies For Multiple Sclerosis, Pengxiang Li, Matthew J Klebanoff, John K Lin, Keya D Doshi, Salim Chahin, Jalpa A Doshi

2020-Current year OA Pubs

No abstract provided.

Enhancing Mental Healthcare Worker Education And Training To Reduce Stigma & Promote Occupational Engagement: An Occupational Therapy Informed Initiative, Emma Rose Osborn

OTD Capstone Projects

Stigma is still a common and often ignored factor that affects health outcomes, especially in mental health care. Stigma is a social problem that affects both caregivers and patients. It is based on deep-seated fears of disease and contagion. Healthcare workers, especially those who work in mental health, are in a unique position to both support and fight these stigmas. Even though this is possible, many healthcare professionals still don't know how much stigma affects patients' experiences and access to care. The goal of this capstone project is to investigate the prevalence of stigma in mental health settings and its …

Retracted: Idea Density And Grammatical Complexity As Neurocognitive Markers, Diego Iacono, Gloria C. Feltis

Department of Neurology Faculty Papers

The journal retracts the article titled “Idea Density and Grammatical Complexity as Neurocognitive Markers” [1], cited above. Following publication, concerns were brought to the attention of the Editorial Office regarding the presence of misnamed phrases and the accuracy of several references cited in this paper [1]. In accordance with the journal’s standard procedures, the Editorial Office and Editorial Board conducted an investigation that confirmed the presence of a misnamed phrase for ROSE model and significant number of non-existent references, which were determined to undermine the overall reliability of this study. In addition, the investigation identified indications of generative AI use …

Effect Of Myrcene On Quality Of Sea Cucumbers During Keeping Alive With Water, Mi Hongbo, Feng Mengmeng, Chen Jingxin, Liu Chao, Li Jianrong, Li Xuepeng

Food and Machinery

[Objective] To investigate the optimal concentration of myrcene and prolong the time of keeping sea cucumbers alive with low-temperature and water. [Methods] The effect of of myrcene concentrations (0, 10, 20, 30, 40, 50 µL/L) on the pH, hardness and soluble protein content of sea cucumbers during keeping alive with water is analyzed. The changes in sensory scores, body wall moisture status and distribution, and microstructure of sea cucumbers before and after keeping alive are compared. The effect of myrcene with the optimal concentration on the immune and antioxidant enzyme activities of sea cucumbers during keeping alive [Results] As the …

Jacquelyn N\'Jai V. Pittsburgh Board Public Education

2026 Decisions

USDC for the Middle District of Pennsylvania

Threat-Analysis Oriented Digital Twinning Of Ml-Powered Future Autonomous Weapon Systems, Thomas Neubert

Doctoral Dissertations and Master's Theses

Warfare is undergoing a rapid transformation with the integration of artificial intelligence (AI) and machine learning (ML) into autonomous weapon systems (AWS) for perception, decision support, and control. As these systems become more software-defined, their cyber attack surface expands across sensing, communications, autonomy logic, and human-machine interfaces. As human oversight diminishes, ensuring the cybersecurity, resilience, and reliability of these systems becomes critical to mission success. This thesis investigates how a digital twin-driven threat modeling framework that integrates system-centric analysis with adversary-informed methodologies can support structured cybersecurity vulnerability evaluation and defensive strategy development associated with ML-powered AWS. First, the study analyzes …

Claudins Interact With Lilrb Immune Inhibitory Receptors To Promote Myeloid Immunosuppression In Cancer, Xiaoye Liu, Ryan Huang, Zhiqiang Ku, Jingjing Xie, Heyu Chen, Yubo He, Qi Lou, Chengcheng Zhang, Xing Yang, Cheryl Lewis, Jade Homsi, Ankit Gupta, Lei Dong, Kenian Chen, Annabel Tu, Liming Du, Hailong Yu, Qing Hu, Meng Fang, Bufan Li, A E M Adan Khan, Caroline Simith, Samuel John, Lin Xu, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang

The Brown Foundation: Institute of Molecular Medicine

The mechanisms underlying tumor cell-myeloid cell interactions in the tumor microenvironment (TME) remain unclear, and predictive biomarkers for patient response to myeloid checkpoint blockade are lacking. This study identified specific binding between tight junction claudins (CLDNs) and leukocyte immunoglobulin-like receptor subfamily B2 (LILRB2) and LILRB5. In multiple human cancer cohorts, the spatial proximity of LILRB2-positive macrophages to CLDN-expressing cancer cells correlated with clinical outcomes, highlighting this spatial relationship as a potential biomarker. In syngeneic LILRB2-transgenic and humanized mouse models, CLDN18.2-LILRB2 interactions triggered bidirectional signaling, enhanced the immunosuppressive activity of myeloid cells, and accelerated tumor progression. These effects were reversed by …

Translationally-Relevant Tumor Resection Model For Murine Preclinical Models Of Oral Squamous Cell Carcinoma, Gemalene M Sunga, Alejandra Cobos Perez, Andrea H Molina, Nourhan Hussein, Neeraja Dharmaraj, Andrew Sikora, Simon Young

Faculty, Staff and Student Publications

Currently, the first-line treatment for the most common form of head and neck squamous cell carcinoma (HNSCC), oral cavity squamous cell carcinoma (OSCC), is surgical resection, followed by risk-adapted treatments, such as chemoradiotherapy. However, with the current standard of care and even the emergence of new treatments, such as checkpoint blockade, the overall survival for advanced, recurrent disease remains high, and the prevalence of head and neck cancer is projected to continue to increase in the coming years. Thus, deeper investigation into current standard-of-care modalities, in addition to novel therapeutics, is necessary to translate potential and promising treatment options to …

The Employment Situation Of Veterans: March 2026, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

Employment rose by 178,000 in March, while the overall unemployment rate held steady at 4.3 percent, with notable job gains in health care, construction, and transportation and warehousing. Veteran unemployment declined slightly to 3.9 percent, though younger veterans continued to experience higher unemployment rates than older veterans and their nonveteran peers. Male veteran unemployment fell, while female veteran unemployment rose and remained above that of nonveteran women. Unemployment trends varied across racial and ethnic groups, with some veteran subgroups showing higher rates than their nonveteran counterparts, though these monthly estimates can fluctuate significantly.

Maps Behind Bars: A Spatial Study Into Wrongful Convictions And Social Equality, Bailee Kinghorn, Emma Milne, Camille Heaton

FHSS Mentored Research Conference

Wrongful convictions are representative of errors in the criminal justice system. Often reflecting broad patterns of social inequality, prior research suggests that structural factors may influence the likelihood of conviction and access to legal resources. This project investigates how these social equality indicators correlate with wrongful convictions at the county level across the United States. Using data from the National Institute of Health and the National Registry of Exonerations, we aggregate measures of education, poverty, and non-English-speaking populations normalized by population density and combine them with exoneration records to create a series of comparative maps. Through spatial analysis in ArcGIS, …