Digital Commons Network^™

Relationship Between Hepatitis B Virus Screening, Vaccination, And Spread In Sierra Leone, Muhammed Sarmodu Mansaray

Walden Dissertations and Doctoral Studies

Hepatitis B virus (HBV) presents a significant public health burden in Sierra Leone. Although the estimated prevalence was 8.7% in 2021, comprehensive statistical data has been limited in general. Programmatic interventions for HBV control such as systematic screening and vaccination have remained limited as well. The purpose of this quantitative cross-sectional study was to examine the relationship between screening and vaccination practices and HBV prevalence in Sierra Leone while controlling for age, sex, education and health care access. The theoretical framework incorporated the Integrated Screening Action model, which highlights screening as a critical disease prevention strategy, and the Social Ecological …

The Association Between Advanced Technology Use And Quality Of Life Among Those With A Disability, Sarah Antus

Walden Dissertations and Doctoral Studies

Advanced medical technology use among individuals with physical disabilities remains understudied, creating a significant gap in understanding its impact on quality-of-life (QoL) outcomes across demographic and age groups. Guided by the social ecological model, the purpose of this quantitative study was to examine associations between advanced medical technology use, disability status, demographic factors (age, gender, and race/ethnicity), and QoL outcomes using 2017–2018 National Health and Nutrition Examination Survey data. The sample included 9,254 individuals age 6 years and older with physical functional limitations and complete technology-use and QoL data. Advanced medical technology use was significantly associated with improved QoL (p < .001). Disability status demonstrated a statistically significant but modest association with technology use, OR = 0.84, 95% CI [0.83, 0.85], p < .001. Age-stratified analyses indicated that advanced technology use significantly predicted improved QoL among adults aged 20 years and older, OR = 6.90, 95% CI [6.89, 6.91], p < .001, but not among youths aged 6–19 years (p = .929). Gender was a significant predictor of technology use, with females having higher odds than males, OR = 1.07, 95% CI [1.06, 1.08], p < .001. Race/ethnicity was also significantly associated with technology use; compared with non-Hispanic White adults, Mexican American (OR = 0.43, 95% CI [0.42, 0.44], p < .001), other Hispanic (OR = 0.58, 95% CI [0.57, 0.59], p < .001), and non-Hispanic Black adults (OR = 0.79, 95% CI [0.78, 0.80], p < .001) had lower odds of advanced medical technology use. The study may inform health care stakeholders about strategies to promote equitable access to advanced medical assistive technologies for social change

2024 Bpsou Stormwater Evaluation And Maintenance Report Annual Stormwater Report For Bpsou Stormwater Structures, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2023 Bpsou Stormwater Evaluation And Maintenance Report Annual Stormwater Report For Bpsou Stormwater Structures, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Lindenwood Digest, April 8, 2026, Lindenwood University

Lindenwood Digest

• Primary Figures: Ken Lanter (United HealthCare Medicare Solutions); Ryan Tomlinson (U.S. Bank Private Wealth Management); Dr. Jennifer Edler, Julie Ingoldsby, Julee Mitsler, and Zeke Chism. 

• Key Events: Lindenwood Giving Week including daily focus areas for campus colleges and athletics; Medicare 101 hybrid information session; Staff Celebration BBQ; Digital Symposium on AI-Augmented Learning; "How to Become a Multi-Millionaire" personal finance presentation; Lindenwood Showcase faculty and student research event. 

• Date/Location: Events scheduled between April 8, 2026, and May 31, 2026, at locations including Spellmann Center, Lindenwood Learning Academy, Pavilion, Dunseth Auditorium (Harmon Hall), and the LARC. 

• Archival Significance: …

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Clingen Api Platform For Classification Of Human Genetic Variants, Neethu Shah, Tierra Farris, Arturo Alejandro Zuniga, Andrew R Jackson, Jessie Arce, Kevin Riehle, Christine G Preston, Mark E Mandell, Bryan Wulf, Gloria Cheung, Keyang Yu, Deborah I Ritter, Dubravka Jevtic, Miroslav Milinkov, Novak Martinovic, Nevena Vucinic, Aleksandar Mihajlovic, Alan F Rubin, Melissa S Cline, Marina Distefano, Malachi Griffith, Obi L Griffith, Matt W Wright, Teri E Klein, Sharon E Plon, Aleksandar Milosavljevic

Faculty, Staff and Students Publications

In this commentary, we describe how the Clinical Genome Resource's (ClinGen's) application programming interface-based microservices accelerate growth and dissemination of knowledge about human genetic variation. By exposing findable, accessible, interoperable, reusable, and AI-ready variant data, ClinGen lays a foundation for next-generation software applications, AI systems, and variant classification workflows.

2023 Bpsou Stormwater Evaluation And Maintenance Report Annual Stormwater Report For Bpsou Stormwater Structures, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2022 Bpsou Stormwater Evaluation And Maintenance Report Annual Stormwater Report For Bpsou Stormwater Structures, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2024 Bpsou Stormwater Evaluation And Maintenance Report Annual Stormwater Report For Bpsou Stormwater Structures, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Preparation And Characterization Of Double-Network Composite Hydrogels With Carboxymethyl Pachymaran In Promoting Wound Healing, Haodong Wu, Xi Feng, Zhinan Mei, Wen Huang, Ying Liu

Faculty Research, Scholarly, and Creative Activity

Utilizing food-derived bioactive polysaccharides in advanced biomedical applications offers significant potential. To effectively harness the inherent bioactivity of Poria cocos, a renowned edible and medicinal fungus, we developed a multifunctional double-network composite hydrogel (CPS) via a feasible one-pot strategy. This was achieved by incorporating functional carboxymethyl pachymaran (CMP) into a matrix of food-grade sodium alginate (SA) and polyacrylamide (PAM). This formulation endows the hydrogel with excellent extensibility, rapid self-healing capabilities, and strong tissue adhesion, all while preserving the biological activity of the natural macromolecules. In a mouse full-thickness skin defect model, the CPS significantly accelerated wound recovery, achieving a healing …

The Clinical And Operational Value Of Early Comprehensive Ngs In Non-Small Cell Lung Cancer, Yunus Emre Demirhan, Marcus Yoakam, Adam Soltani, Arshdeep Gill, Samir Dalia

Student Publications

Lung cancer remains the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for most cases. Advances in targeted therapies and immunotherapy have improved outcomes, but their benefit depends on timely molecular characterization. Early next-generation sequencing (NGS), performed at or near diagnosis, is increasingly used to identify actionable alterations and inform first-line and perioperative treatment planning. In this review, we examine the clinical, operational, and economic rationale for early comprehensive NGS in NSCLC. Upfront sequencing can improve diagnostic yield, preserve limited tissue, reduce turnaround time, and help avoid non-matched systemic therapy. Practical implementation strategies include Molecular …

High-Throughput Multiplex Detection Of Respiratory Pathogens: Multicenter Evaluation Of The Nxtag Respiratory Pathogen Panel V2 Assay., Marisa C. Nielsen, Ping Ren, Sri Bharathi Kavuri, Karissa Culbreath, Rangaraj Selvarangan, Dithi Banerjee, Blake W. Buchan, Rachel Behounek, Janet Farhang

Manuscripts, Articles, Book Chapters and Other Papers

Respiratory tract infections remain a major cause of global morbidity, highlighting the need for rapid and accurate diagnostic testing. This multicenter study evaluated the clinical and analytical performance of the updated NxTAG Respiratory Pathogen Panel v2 (RPPv2), a high-throughput multiplex molecular assay designed to detect 21 viral and bacterial respiratory pathogens. A total of 2,145 nasopharyngeal swab specimens, including both prospectively enrolled and archived specimens, were analyzed across five U.S. clinical sites. The NxTAG RPPv2 was assessed against FDA-cleared molecular assays and bi-directional sequencing, with contrived specimens used to supplement low-prevalence targets. Valid results were obtained for 99.7% of specimens …

Characterization Of Subclonal Variants In Hg002 Genome In A Bottle Reference Material As A Resource For Benchmarking Variant Callers., Camille A. Daniels, Adetola A. Abdulkadir, Megan H. Cleveland, Jennifer H. Mcdaniel, David Jáspez, Luis Alberto Rubio-Rodríguez, Adrián Muñoz-Barrera, José Miguel Lorenzo-Salazar, Carlos Flores, Byunggil Yoo, Sayed Mohammad Ebrahim Sahraeian, Yina Wang, Massimiliano Rossi, Arun Visvanath, Lisa Murray, Wei-Ting Chen, Severine Catreux, James Han, Rami Mehio, Gavin Parnaby, Andrew Carroll, Pi-Chuan Chang, Kishwar Shafin, Daniel Cook, Alexey Kolesnikov, Lucas Brambrink, Mohammed Faizal Eeman Mootor, Yash Patel, Takafumi N. Yamaguchi, Paul C. Boutros, Karolina Sienkiewicz, Jonathan Foox, Christopher E. Mason, Bryan R. Lajoie, Carlos A. Ruiz-Perez, Semyon Kruglyak, Justin M. Zook, Nathan D. Olson

Manuscripts, Articles, Book Chapters and Other Papers

We developed a benchmark set of subclonal variants in the Genome in a Bottle (GIAB) Consortium HG002 reference material (RM) DNA for evaluating lower-frequency variant callsets. We used a somatic variant caller with high-coverage (300×) whole-genome sequencing data from the GIAB Ashkenazi Jewish trio to identify potential subclonal variants in the HG002 RM DNA. Using orthogonal sequencing data and manual curation, we defined a benchmark set with 85 high-confidence subclonal single-nucleotide variants (SNVs) (allele frequency [AF] > 5%) and a benchmark region covering 2.45 Gbp of the autosomes. External validation supported that it can be used to reliably identify both false …

Costs, Demographics, And Causative Agents In Patients Hospitalized For Drug Induced Liver Injury: Trends In A Large Academic Healthcare System, Megan Kozar, Yunisse Gonzalez, Dina Halegoua-De Marzio

Department of Medicine Faculty Papers

PURPOSE: Drug-induced liver injury (DILI) is an uncommon but potentially life-threatening condition. To date, the burden of DILI on a single, large healthcare system has not been investigated, preventing adequate resource allocation. This study aims to quantify DILI-related healthcare utilization within the Jefferson Health System (JHS) and identify case-related factors associated with high resource requirements; such information is crucial to focus efforts toward resource reduction.

PATIENTS AND METHODS: This study characterizes trends of 48 DILI cases within JHS, including demographics, payer status, causative agent, and DILI pattern. These variables were correlated with length of stay (LOS) and cost relating to …

The Density Dilemma: Reconciling Energy Efficiency And Social Well-Being In Compact Housing, Adeb Ebrahim

Architecture and Planning Journal (APJ)

This study examines compact housing not only in terms of urban design. From a sequential exploratory mixed-methods approach study on 120 residential units in Sana’a, we observed that there is a paradox where energy modular housing consumes 28% less energy, but social isolation increases 22%. However, this paradox is countered by the design of biophilic shared spaces (β = -0.34). This research establishes a case for more equitably accessible policies on density and proposes that high-density urban fabrics must have a “social connector” code. This study integrates Fainstein's (2020) concept of the 'just city' and contemporary housing innovations into the …

Exploring Teachers’ Perceptions Of School Counselor-Principal-Teacher Collaboration, Collective Teacher Efficacy, And Leadership, Rachel Louise Geesa, Sherri Barrow, Rochelle Maynard, Derien D. Kunce

Mid-Western Educational Researcher

Efforts to support students' academic, social/emotional, personal, and future professional well-being often rely on the collaboration among educational leaders, educators, and community partners. In this study, we examine teachers' perceptions of collaboration among school counselors, principals, and teachers to enhance school culture, with a focus on collective teacher efficacy. We also provide insights for school leaders (e.g., principals, school counselors, and teachers) to implement systemic changes that promote collaboration and student success. This study is framed through the social cognitive theory, where self-efficacy shapes how educators perceive their ability to impact the learning environment and engage students. Using a mixed-methods …

The Shorthorn: December 4, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: December 5, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: December 3, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 26, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 21, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 14, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 12, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 7, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 11, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 5, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 6, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: October 31, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 4, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: October 30, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.