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Evaluation Of The Association Between School Prevention Programs And Adolescents’ Opioid Abuse In The United States, Lida Moazezi Sep 2026

Evaluation Of The Association Between School Prevention Programs And Adolescents’ Opioid Abuse In The United States, Lida Moazezi

Walden Dissertations and Doctoral Studies

This study examined adolescent opioid misuse in the United States and the role of school-based prevention. Guided by the health belief model, the purpose was to test whether participation in school-based drug prevention lessons was associated with past-year opioid misuse among adolescents ages 14–17 and whether race and gender moderated that association. This quantitative, cross-sectional, nonexperimental secondary analysis used the 2019 National Survey on Drug Use and Health (N = 8,965). Analyses included weighted descriptives, chi-square tests, and complex-samples logistic regression controlling for age and socioeconomic status. The sample included adolescents ages 14–17 with complete data on school-based prevention participation, …


Exploring Multicultural Competence Among Mental Health Workers When Providing Treatment To African American Males, Ashley Hightower Sep 2026

Exploring Multicultural Competence Among Mental Health Workers When Providing Treatment To African American Males, Ashley Hightower

Walden Dissertations and Doctoral Studies

African American men experience disproportionately low rates of mental health service utilization and often report negative perceptions of mental illness. Despite documented mental health disparities, limited research has explored how mental health workers understand and apply multicultural competence when providing treatment to African American men. Grounded in the theory of planned behavior and social identity theory, the purpose of this qualitative descriptive phenomenological study was to explore the lived experiences of mental health workers regarding multicultural competence in their work with African American men. Data were collected through semi-structured interviews with seven mental health workers recruited through purposive sampling. Interview …


Smaller State Development By Competitiveness In Productivity And Sustainability, Anthony Wayne Jerome Phillips-Spencer Sep 2026

Smaller State Development By Competitiveness In Productivity And Sustainability, Anthony Wayne Jerome Phillips-Spencer

Walden Dissertations and Doctoral Studies

Persistent poverty, middle-income traps, uneven growth, and productivity gaps expose smaller countries, defined as those with fewer than nine million people, to multidimensional vulnerability that retards development. Research revealed a positive relationship between competitiveness and growth in larger and developed countries. However, the competitiveness-development nexus in smaller and developing countries was omitted from previous research. Growth is not development. The purpose of this quantitative, longitudinal, comparative study was to examine the development-by competitiveness experiences of smaller states at different stages of development with productivity and sustainability through the lens of punctuated equilibrium theory and the national competitive development model. Results …


Characterization Of An Open-Channel Structure And Lateral Conduction Pathway In The Cation-Selective Pentameric Ligand-Gated Ion Channel, Elic, Mark J Arcario, Elizabeth J Wu-Chen, Yuna Shim, Jérôme Hénin, Grace Brannigan, Wayland W L Cheng Sep 2026

Characterization Of An Open-Channel Structure And Lateral Conduction Pathway In The Cation-Selective Pentameric Ligand-Gated Ion Channel, Elic, Mark J Arcario, Elizabeth J Wu-Chen, Yuna Shim, Jérôme Hénin, Grace Brannigan, Wayland W L Cheng

2020-Current year OA Pubs

Open-channel structures of multiple pentameric ligand-gated ion channels (pLGICs) have been determined, including the prokaryotic model pLGIC, Erwinia ligand-gated ion channel (ELIC). For many of these structures, it remains uncertain whether they represent a physiologic open-channel state because the conditions used for structure determination do not match those of functional measurements in cell membranes. Here, MD simulation is used to examine the ion conduction properties of the ELIC open-channel structure, which was determined using a non-desensitizing mutant called ELIC5. Results from simulations show that the pore remains stably open on the microsecond timescale, but computational electrophysiology measurements demonstrate a large …


Global, Regional, And National Prevalence Of Second-Hand Smoke And Attributable Disease Burden In 204 Countries And Territories, 1990–2023: A Systematic Analysis For The Global Burden Of Disease Study 2023, Gbd 2023 Second-Hand Smoke Collaborators, Debasish Kar Sep 2026

Global, Regional, And National Prevalence Of Second-Hand Smoke And Attributable Disease Burden In 204 Countries And Territories, 1990–2023: A Systematic Analysis For The Global Burden Of Disease Study 2023, Gbd 2023 Second-Hand Smoke Collaborators, Debasish Kar

Peninsula Medical School

SummaryBackground Second-hand smoke (SHS) exposure remains a major source of morbidity and mortality among nonsmokers. This study presents the first dedicated Global Burden of Diseases, Injuries, and Risk Factors Study (GBD)publication to systematically quantify SHS prevalence and evaluate its effect as a global risk factor across a broaderrange of outcomes.Methods Using the GBD 2023 comparative risk assessment framework, we estimated SHS exposure prevalence andattributable disease burden across 204 countries and territories from 1990 to 2023, stratified by age and sex. Exposureestimates were derived by synthesising population-based surveys and household composition data throughspatiotemporal Gaussian process regression. Relative risks for nine health …


Repeatability And Behavioral Relationships Of Acuity, Contrast Sensitivity, Form, And Motion Perception Measurements Using A Novel Tablet-Based Vision Test Tool, Jonathan Green, Jan Skerswetat, Peter J. Bex, Gunnar Schmidtmann Sep 2026

Repeatability And Behavioral Relationships Of Acuity, Contrast Sensitivity, Form, And Motion Perception Measurements Using A Novel Tablet-Based Vision Test Tool, Jonathan Green, Jan Skerswetat, Peter J. Bex, Gunnar Schmidtmann

School of Health Professions

Visual function tests are essential in basic and clinical vision research but are typically restricted to a limited range of visual functions and provide coarse diagnostic resolution. The response-adaptive Angular Indication Measurement (AIM) and Foraging Interactive D-prime (FInD) paradigms were recently developed as generalizable approaches for assessing multiple visual functions. Both methods present 4 × 4 stimulus arrays spanning ± 2σ around an adaptively estimated threshold. This study evaluated the repeatability, test duration, and relationships between AIM and FInD measures of near visual acuity (VA), contrast sensitivity function (CSF), and form and motion coherence using tablet-based vision tests. 38 healthy …


A Realist Review Of The Remediation Of Professionalism Lapses In Undergraduate Medical Students (Restore 3), Ross Raymond-Jones, Tom Gale, Nicola Brennan, Marie Bryce, Tristan Price Sep 2026

A Realist Review Of The Remediation Of Professionalism Lapses In Undergraduate Medical Students (Restore 3), Ross Raymond-Jones, Tom Gale, Nicola Brennan, Marie Bryce, Tristan Price

Peninsula Medical School

IntroductionProfessionalism is a core element of medical curricula worldwide and remains a cross-cutting theme across all aspects of a medical programme. When a medical student fails to demonstrate the expected attributes and behaviours, medical schools have a duty to step in, and where appropriate, offer remediation that aims to facilitate behavioural change. There is sparse explanatory theory on this complex topic, resulting in little evidence-based guidance for medical schools to utilise. This review aims to explain how, why, to what extent and in what circumstances professionalism remediation works for undergraduate medical students.MethodWe conducted a realist review that aligns with the …


Unsex Me Here: Gendered Psychology In Shakespeare's Major Tragedies And Comedy, Md. Abu Bakkar Sep 2026

Unsex Me Here: Gendered Psychology In Shakespeare's Major Tragedies And Comedy, Md. Abu Bakkar

Journal of Language, Literature, and Arts

This study examines how gender shapes psychological experience across five of Shakespeare’s major plays: Macbeth, Hamlet, Othello, King Lear, and Twelfth Night. Existing scholarship treats Shakespeare’s tragic women, tragic men, and comic heroines as separate problems; this article asks whether one framework connects them. Its starting point is the reversal in psychological positions between Macbeth and Lady Macbeth: he resists killing on moral grounds and then grows recklessly violent, while she plans the murder with cold resolve and is later overwhelmed by guilt. The study asks whether this pattern recurs more broadly, and why. Drawing …


Prevalence And Characteristics Of Feline Pleural Effusion In Khon Kaen, Thailand: A 2024–2025 Study, Karn Yongvanit, Naruepon Kampa Sep 2026

Prevalence And Characteristics Of Feline Pleural Effusion In Khon Kaen, Thailand: A 2024–2025 Study, Karn Yongvanit, Naruepon Kampa

The Thai Journal of Veterinary Medicine

Pleural effusion (PE) is a life-threatening condition in cats that can cause severe respiratory compromise. Identification of the underlying etiology is essential for prognosis and treatment planning. This study investigated the prevalence and characteristics of diseases associated with feline pleural effusion in northeastern Thailand. Medical records of cats diagnosed with pleural effusion at the Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Khon Kaen University, Thailand, between January 2024 and January 2025 were retrospectively reviewed. Cases lacking a complete diagnostic workup were excluded. Diagnoses were confirmed using cytology or histopathology for neoplasia, echocardiography for heart disease, polymerase chain reaction (PCR) for …


Enhancing Clinical Trial Literacy In Singapore: A Dnp Evaluation Of A Hbm-Guided Educational Video, Harini S. Shunmuga Velu, Barnaby Edward Young, Wentao Zhou Sep 2026

Enhancing Clinical Trial Literacy In Singapore: A Dnp Evaluation Of A Hbm-Guided Educational Video, Harini S. Shunmuga Velu, Barnaby Edward Young, Wentao Zhou

International Nursing Research Congress (INRC)

Background: Clinical trials are a cornerstone of modern healthcare [4]. However, approximately 80% of trials fail to enrol participants on time, costing millions and delaying essential treatment [1].This directly impedes progress toward Sustainable Development Goal Target 3.b. In Singapore, community participation remains modest due to micro-level barriers, including misconceptions, fear of exploitation, and limited research literacy. Advanced nursing leadership must promote this by promoting research literacy and informed ethical decision-making.

Purpose: The purpose is to systematically evaluate the effectiveness and implementation feasibility of a short, culturally-tailored educational video designed to enhance public knowledge, perceived safety, and willingness to participate in …


Building An Engaged Workforce: Assessment Of Unit Council Health Within A Large Healthcare System, Ray Gannon, Kasey Jackman, Reynaldo R. Rivera Sep 2026

Building An Engaged Workforce: Assessment Of Unit Council Health Within A Large Healthcare System, Ray Gannon, Kasey Jackman, Reynaldo R. Rivera

International Nursing Research Congress (INRC)

While professional governance is an effective strategy for improving team engagement and empowerment in hospital systems, fews studies provide guidelines for how to measure the relative health of an organization's professional governance. Of note, the effectiveness of the unit council is fundamental to successful professional governance, professional competence, and leadership (Hess et al., 2020).

The purpose of this multi-site survey study is to evaluate clinical nurses’ and nurse leaders’ perspectives on their unit council’s health so that our organization can identify the gaps and implement strategies for improvement.

Led by a team of nurse scientists and leaders, this is an …


The Utilization Of Augmented Reality Haptic Feedback For Simulation-Based Education: A Quality Improvement Project, Arielle Kayla Vargas, Yasmine N. Campbell, Valerie J. Diaz Sep 2026

The Utilization Of Augmented Reality Haptic Feedback For Simulation-Based Education: A Quality Improvement Project, Arielle Kayla Vargas, Yasmine N. Campbell, Valerie J. Diaz

International Nursing Research Congress (INRC)

Background: Central line placement (CLP) is a critical skill for nurse anesthesiology residents, yet proficiency gaps can lead to serious complications, including arterial puncture, hematoma, and pneumothorax. Although ultrasound guidance is the current standard for teaching this procedure, it lacks tactile feedback, which limits learners’ spatial awareness and control—both essential for accurate needle tip tracking (NTT). This shortcoming in traditional simulation-based education (SBE) contributes to inconsistent skill acquisition and potential patient harm. . This project aimed to determine whether, among nurse anesthesiology residents, the use of AR haptic feedback versus ultrasound-guided methods in SBE would improve success in needle tip …


Innovative Teaching Strategies: Ai Chatbots To Prepare Nursing Students For Difficult Conversations, Lindsay Iverson, Tamara Oliver, Steven Fernandes, Mandy Kirkpatrick, Kara Morgan, Lauren Guthrie, Trisha Beiermann, Melissa Taylor Sep 2026

Innovative Teaching Strategies: Ai Chatbots To Prepare Nursing Students For Difficult Conversations, Lindsay Iverson, Tamara Oliver, Steven Fernandes, Mandy Kirkpatrick, Kara Morgan, Lauren Guthrie, Trisha Beiermann, Melissa Taylor

International Nursing Research Congress (INRC)

Background and Significance: Therapeutic communication is a core competency in nursing and a consistently prioritized workforce requirement (Broeckelman-Post et al., 2022; McGunagle & Zizka, 2020; AACN, 2021). As AI and digital learning technologies advance, nursing programs are exploring technology-enabled strategies to better prepare students for emotionally complex patient interactions. Although AI chatbots have shown value in clinical training and simulation (Chang et al., 2021; Srinivasan et al., 2024), limited evidence exists on their use to prepare students for difficult or sensitive conversations. Addressing this gap supports student resilience and prepares future nurses for communication-intensive roles.

Purpose and Aims: This study …


Optimizing Research To Practice Translation Time Through The Mountain Model: A Delphi Study, Jayne Jennings Dunlap, Julee Waldrop, Staci Reynolds Sep 2026

Optimizing Research To Practice Translation Time Through The Mountain Model: A Delphi Study, Jayne Jennings Dunlap, Julee Waldrop, Staci Reynolds

International Nursing Research Congress (INRC)

Introduction: The Mountain Model (MM) is the first published framework to merge evidence-based practice and quality improvement (EBPQI) paradigms. The primary focus of the framework is to guide practitioners in healthcare and related settings with translating research for sustained practice improvements. The nurse-led MM is in use and being cited in the literature, however the efficacy of the MM is anecdotal and is not yet supported by empirical evidence for its validity.

Design: A Delphi study of currently practicing evidence-based practice (EBP) and quality improvement (QI) experts spanning eight patient-facing disciplines in healthcare was conducted in September and October 2025 …


From Protection To Provision, Not Participation: A Bibliometric Analysis Of Children's Digital Rights Research And Its Implications For Media Literacy Education, Author Information Removed Sep 2026

From Protection To Provision, Not Participation: A Bibliometric Analysis Of Children's Digital Rights Research And Its Implications For Media Literacy Education, Author Information Removed

JMLE Submissions Open for Review

Media literacy education is widely held to have moved from a protective to a participatory paradigm. This study asks whether the children's digital rights literature that informs it has made the same move. Records were retrieved from Web of Science and Scopus (search date 31 August 2026), screened, and deduplicated, yielding 1,012 publications from 1993 to 2026. A dictionary built on the protection–provision–participation framework of the Convention on the Rights of the Child was applied to 4,507 keywords. Protection accounted for 40.4% of classified keywords, provision for 44.4%, and participation for 15.1%. Protection exceeded participation by 2.4 to 3.1 throughout, …


Approval Letter For The Draft Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites Field Sampling And Investigation Plan – Ur-52 Area West Of Bres No. 133 – Dexter Mill, Molly Roby Sep 2026

Approval Letter For The Draft Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites Field Sampling And Investigation Plan – Ur-52 Area West Of Bres No. 133 – Dexter Mill, Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Approval Letter For The Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites Field Sampling And Investigation Plan: Ur-53 – South Of Surprise Dump, Molly Roby Sep 2026

Approval Letter For The Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites Field Sampling And Investigation Plan: Ur-53 – South Of Surprise Dump, Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Recommencement Of Anti-Thrombotics Following Traumatic Intracranial Haemorrhage; A Preliminary Survey Of Uk Consultant Neurosurgeons Informing The Restart-Ticrh Trial Design, Jack Read, Peter Whitfield, Michael D. Jenkinson, Catherine J. Mcmahon, Ellie Edlmann Sep 2026

Recommencement Of Anti-Thrombotics Following Traumatic Intracranial Haemorrhage; A Preliminary Survey Of Uk Consultant Neurosurgeons Informing The Restart-Ticrh Trial Design, Jack Read, Peter Whitfield, Michael D. Jenkinson, Catherine J. Mcmahon, Ellie Edlmann

Peninsula Medical School

Introduction: Traumatic intracranial haemorrhage (tICH) commonly follows falls in elderly people, around half of whom are taking anti-thrombotic (AT) medications pre-injury. ATs are typically stopped acutely, but guidance on safe recommencement is limited. Research question: We surveyed UK neurosurgical consultants to understand variations in AT recommencement practice and inform trial design. Materials and methods: An online cross-sectional survey was distributed via the Society of British Neurological Surgeons mailing list to assess self-reported consultant practice regarding cessation and recommencement of AT therapy following tICH. Results: Sixty-two consultant neurosurgeons responded. Following tICH most are very likely or likely to stop AT therapy …


Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) 2025 Butte Reclamation Evaluation System (Bres) Site Specific Corrective Action Plans For Quadrant 2 (Dated July 22, 2026), Molly Roby Sep 2026

Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) 2025 Butte Reclamation Evaluation System (Bres) Site Specific Corrective Action Plans For Quadrant 2 (Dated July 22, 2026), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Re: Approval Letter For The Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites Field Sampling And Investigation Plan: Ur 51 – Area Near Bres No.50 –Zelia And Mountain Con Mine, Molly Roby Sep 2026

Re: Approval Letter For The Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites Field Sampling And Investigation Plan: Ur 51 – Area Near Bres No.50 –Zelia And Mountain Con Mine, Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Flipbook-Based Media To Prevent Academic Burnout Among Senior High School Students In Yogyakarta, Puan Maharani Fauza, Eva Imania Eliasa, Kun Widya Nurfiani Sep 2026

Flipbook-Based Media To Prevent Academic Burnout Among Senior High School Students In Yogyakarta, Puan Maharani Fauza, Eva Imania Eliasa, Kun Widya Nurfiani

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Academic burnout is a pressing issue that negatively affects senior high school students, yet conventional counseling services often rely on monotonous, static media that fail to engage today's digital generation. To address this urgent gap, this research aimed to develop an interactive digital Flipbook as a preventive intervention. The study employed a Research and Development (R&D) method using the ADDIE model, consisting of Analysis, Design, Development, Implementation, and Evaluation stages. Product validation was conducted by media experts and subject-matter experts, while the practicality test involved two Guidance and Counseling teachers. The effectiveness test was carried out through an experimental study …


Ai-Enabled Nudging For Nursing-Led Prevention And Health Equity, Pattama S. Ulrich, Katherine M. Pallas, Michael Joseph Dino, Jean W. Davis Sep 2026

Ai-Enabled Nudging For Nursing-Led Prevention And Health Equity, Pattama S. Ulrich, Katherine M. Pallas, Michael Joseph Dino, Jean W. Davis

International Nursing Research Congress (INRC)

Health systems face escalating burdens from physical inactivity, poor nutrition, and related noncommunicable diseases (NCDs), which disproportionately affect socioeconomically and clinically susceptible populations [1], [2]. Concurrently, artificial intelligence (AI), digital health technologies, and wearable devices are increasingly shaping health decision making and behavior change interventions [3], [4]. Nudge theory, grounded in behavioral economics, offers a noncoercive approach to influencing behavior through choice architecture while preserving individual autonomy [5], [6]. As AI enables nudges to become more personalized and scalable, conceptual clarity is needed to guide ethical, nurse-led applications that advance prevention and health equity [7], [8].

This work conceptually examines …


Parent–Child Responses To A Digital Cancer Prevention Game: Pre–Post Changes In Hpv-Related Outcomes, Angela Chia-Chen Chen, Michael Todd, Elizabeth Reifsnider, Ashish Amresh Sep 2026

Parent–Child Responses To A Digital Cancer Prevention Game: Pre–Post Changes In Hpv-Related Outcomes, Angela Chia-Chen Chen, Michael Todd, Elizabeth Reifsnider, Ashish Amresh

International Nursing Research Congress (INRC)

Purpose: This presentation examined pre–post changes among parent–child dyads who received HPV Detective, a digital game promoting HPV vaccination and cancer prevention. We compared intervention effects between parents and children to understand how digital tools influence family-centered determinants of HPV vaccination.

Methods: Thirty-one parent–child dyads (n=62) completed online surveys at baseline (T0) and immediately post-intervention (T1) while playing the 10–15-minute game in pediatric clinics before seeing the provider. Surveys included sociodemographic characteristics and validated scales assessing HPV knowledge, attitudes, behavioral control, subjective norms, and vaccination intention. Paired t-tests and descriptive analyses assessed within-person changes, with results confirmed using nonparametric tests. …


Patient-Provider Communication Matters In Telehealth Use, Chanam Shin, Thomas Guffey, Mijin Kim Sep 2026

Patient-Provider Communication Matters In Telehealth Use, Chanam Shin, Thomas Guffey, Mijin Kim

International Nursing Research Congress (INRC)

Introduction: Telehealth use has rapidly expanded health care access and reshaped patient-provider interactions. Evidence shows that telehealth can be influenced by communication quality between patients and providers. However, little is known about how patient-provider communication relates to telehealth use among minority ethnic populations.

Purpose: This study was to examine associations between patient-centered communication and telehealth use in Asian Americans.

Methods: We conducted a secondary analysis using the 2022 Health Information National Trends Survey 6 data. A total of 265 adults who identified as Asian American were included. Telehealth use was assessed by asking respondents if they used telehealth in the …


Machine Learning In Pediatric Surgery: Validation For Ambulatory Screening, Mary Beth Bass, Jill Kinch, Kimberly Isenberg Sep 2026

Machine Learning In Pediatric Surgery: Validation For Ambulatory Screening, Mary Beth Bass, Jill Kinch, Kimberly Isenberg

International Nursing Research Congress (INRC)

Accurate screening for anesthesia eligibility criteria is crucial for pediatric ambulatory surgery centers (ASCs) to ensure patient safety and optimization of resources [1,3]. Traditional manual chart review by advanced practice providers (APPs) is labor-intensive and subject to variability [2, 3, 7]. Continued growth of the ASC patient volume creates challenges for the APP team to meet the patient safety needs without adding additional support. To address these challenges, we partnered with Brim Analytics (Brim), an Artificial Intelligence (AI) powered chart review tool built on a large language model. Brim interprets unstructured electronic medical record (EMR) data and applies our institutional …


Satellite-Based Assessment Of Hydrologic Synchronization Across Western U.S. Basins: Implications For Water Security, Calef Alesse, Thomas Piechota, Josh Fuery, Landon Kauer, Venkataraman Lakshmi Sep 2026

Satellite-Based Assessment Of Hydrologic Synchronization Across Western U.S. Basins: Implications For Water Security, Calef Alesse, Thomas Piechota, Josh Fuery, Landon Kauer, Venkataraman Lakshmi

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Study Region

This study examines the Western United States including five HUC2 watersheds (Upper Colorado, Lower Colorado, Great Basin, California, Pacific Northwest) and 44 HUC4 sub-basins. This region supports over 60 million people and extensive agriculture with water stress from climate change and multi-year droughts.

Study Focus

Hydrologic synchronization is quantified using satellite datasets (GLDAS runoff, PRISM precipitation, SMAP soil moisture) and analytical methods including cross-correlation, Principal Component Analysis, co-occurrence analysis, lagged correlation, and whiplash analysis to identify spatial patterns, synchronized extremes, and lead-lag relationships.

New Hydrological Insights for the Region

The California-Great Basin pair shows 65% runoff synchronization and …


Phenotypic And Genotypic Risk Factors For Fatigue Trajectories In Early-Stage Breast Cancer Patients, Katrina Carr, Susan M. Sereika, Yvette Conley, Susan Wesmiller Sep 2026

Phenotypic And Genotypic Risk Factors For Fatigue Trajectories In Early-Stage Breast Cancer Patients, Katrina Carr, Susan M. Sereika, Yvette Conley, Susan Wesmiller

International Nursing Research Congress (INRC)

Introduction: Cancer-related fatigue (CRF) is the most burdensome symptom in early-stage breast cancer (ESBC) patients; up to 30% report severe fatigue one-year post-diagnosis. CRF significantly impairs quality of life and functional status. Identifying risk factors for distinct fatigue trajectories can inform symptom management timing and personalization.

Purpose: Identify distinct trajectories and phenotypic and genotypic risk factors associated with high severity fatigue trajectories in women with ESBC.

Methods: This analysis of a prospective longitudinal study examined genetic underpinnings of symptoms in ESBC patients. Fatigue was assessed using the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS®29) weekly during treatment and monthly thereafter …


From Himalayan Catastrophe To National Resilience: Lessons From The 2026 Bhote Koshi And Trishuli River Floods In Nepal, Keshav Bhattarai, Ambika P. Adhikari Sep 2026

From Himalayan Catastrophe To National Resilience: Lessons From The 2026 Bhote Koshi And Trishuli River Floods In Nepal, Keshav Bhattarai, Ambika P. Adhikari

Himalayan Research Papers Archive

On the morning of 26 August 2026, the mountains above Nepal’s northern frontier delivered a disaster of almost unimaginable speed and scale. A massive mass of ice, rock, and sediment detached in the high Himalayan terrain near the Nepal–Tibet border, descended roughly 1,200 metres, interacted with the Lhende Khola system, and generated a debris-rich flood that surged through the Bhote Koshi and Trishuli river corridors, destroying settlements, markets, roads, bridges, hydropower facilities, and an international border crossing and transforming them into fields of mud, boulders, and wreckage within minutes (ICIMOD, 2026b; Reuters, 2026a). Satellite analysis indicates that a substantial section …


Neuroimmune Phenotyping As The Next Frontier In Chronic Pain Medicine For Musculoskeletal Back Pain, Samer G. Salman, Rohan A. Phadke, Adithya Nair, Rahul Kumar, Arbaz Momin, Alireza Tavakkoli, James Rizkalla Sep 2026

Neuroimmune Phenotyping As The Next Frontier In Chronic Pain Medicine For Musculoskeletal Back Pain, Samer G. Salman, Rohan A. Phadke, Adithya Nair, Rahul Kumar, Arbaz Momin, Alireza Tavakkoli, James Rizkalla

Department of Neurosurgery Posters

Background: Chronic low back pain encompasses heterogeneous mechanical, neuropathic, nociplastic, and myofascial presentations that may reflect distinct neuroimmune mechanisms. We synthesized evidence linking these phenotypes to measurable biological features and clinically relevant treatment strategies.

Methods: We conducted a structured literature search of MEDLINE, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials for studies published from January 2005 through January 2025. Systematic reviews, randomized controlled trials, and mechanistic studies addressing neuroinflammation, glial activation, central sensitization, biomarkers, or imaging were organized according to four clinically relevant pain phenotypes and translational readiness.

Results: Neuroimmune findings differed across axial mechanical, …


Manipulation Leading To Criminalization: The Need To Expand Georgia’S Survivors First Act, Taylor Hoying Sep 2026

Manipulation Leading To Criminalization: The Need To Expand Georgia’S Survivors First Act, Taylor Hoying

Georgia Criminal Law Review

Nicole was seventeen when she met Juan, and they began a romantic relationship. “He was gorgeous and he had charm. I just wanted someone in my life to show me attention . . . .” He suggested that she start seeing other dates for money and sent her out onto the streets. Seven months later, when Nicole was raped by a john, Juan beat her, pepper-sprayed her, and put her in a cold shower for three and a half hours. If Nicole had been told to see another john the next day and was arrested for prostitution, would the arrest …