Digital Commons Network^™

Preparation And In-Vitro Evaluation Of Tizanidine Flash Oral Dispersible Tablet, Ahmed Yousif Fadhel, Yousif K. Younis

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Background: Oral administration is the most common and preferred route for drug delivery. Oral dispersible tablets (ODTs) are solid dosage forms that disintegrate into saliva without the need for water. Tizanidine is a centrally acting muscle relaxant used to manage spasticity from spinal or brain injuries. Preparing it as a flash (ODT) tablet may enhance patient compliance and potentially improve bioavailability by bypassing part of the first-pass metabolism. Methods: Six formulations of tizanidine flash tablets were developed using varying concentrations of mannitol (bulk-forming agent), glycine (to aid tablet collapse), and gelatin (matrix-forming agent). The formulations were evaluated for weight variation, …

The Impact Of People Interests In Evaluating The Open Public Spaces' Quality In The City Centre, Hasan Hadi, Adil Al-Saidi, Haitham Alshamari

HBRC Journal

The quality of open public spaces in city centres significantly affects people's satisfaction and responses to their built environment. The significance of these areas allow people to assess their performance. this paper addresses the issue of People's interests that affect their evaluation of public urban spaces in city centres. The research applied an ontological methodology that is people's experiences determine the spatial quality of the public spaces in city centres. In order to discover and assess the seven value variables, it recommended diagnosing a random sample of users as a group (A) and (B). The urban space in the historic …

Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik

AUIQ Complementary Biological System

Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …

Evaluation Of Circulating Hpg80, Ca15-3, Estrogen And Progesterone As Biomarkers In Breast Cancer Patients, Safa Khaldoon, Emad Yousif, Khawla A. Kasar, Muna Bufaroosha, Rahimi Yusop

AUIQ Complementary Biological System

It is very important to find reliable biomarkers for early detection and monitoring of treatment response because breast cancer is still one of the most common cancers in women around the world. The goal of this study was to find out how clinically important different biochemical markers are in Iraqi women with breast cancer. Some of these signs are progesterone (PG), oestrogen (E2), cancer antigen 15-3 (CA15-3), and circulating progastrin (hPG80). There were 100 women in this study, and they were all between the ages of 20 and 70. There were three groups of people who took part: a healthy …

Synergistic Endocytic Receptor Ligand Receptor Protein 2 In T2dm, Wafaa Raji Alfatlawi

AUIQ Complementary Biological System

Purpose: The glycoprotein molecule known as megalin is present on the proximal renal tubular epithelial cells. With an emphasis on megalin and cubilin levels in T2DM and IR patients, an area that obviously needs more research, this study attempts to give an outline of current knowledge of megalin function in relation to vitamin D and its metabolite (vitamin D receptor and vitamin D binding protein). Materials and Methods: This was a case control comparative study conducted at a endocrine and diabetes center in AL-Imamain Kadumain teaching hospital in Baghdad-Iraq. Study subjects were divided into three groups: 25 with T2DM with …

From Waste To Wardrobe: Bridging Consumer Behavior And Circular Fashion For A Sustainable Industry, Gabriela V. Petrova

Honors Capstones

• Fast fashion drives environmental damage: water pollution, microplastics, and chemical exposure.

• Consumer behavior and systemic barriers reinforce unsustainable practices.

• Circular fashion—reuse, resale, and rental—offers opportunities to reduce waste.

• Success depends on both industry innovation and shifts in consumer habits.

Optimizing Glycemic Control In Type Ii Diabetes: Continuous Glucose Monitoring : A Scoping Review, Sarah Poe, Bsn, Rn, Bailey Li, Bsn, Rn, Tracy Mcclinton, Dnp, Aprn, Ag-Acnp-Bc, Hget-C, Ebp-C

Doctor of Nursing Practice Projects

Purpose/Background

Individuals with Type II diabetes mellitus (T2DM) experience increased risk of cardiovascular disease and higher mortality rates relative to non-diabetic populations. Continuous glucose monitoring (CGM) enables more precise analysis of glucose patterns and trends compared to conventional self-monitoring of blood glucose (SMBG). CGM provides frequent measurements and generate meaningful metrics, such as time in range (TIR), time above range (TAR), and time below range (TBR), allowing evaluation of glucose stability and variability. Despite these advantages, evidence comparing CGM and SMBG remains inconsistent. This scoping review aims to evaluate how CGM compares with SMBG across reported outcomes, including TIR, TAR, …

Diagnostic Overlap In Hus: An Atypical Case, Ryan Daily, Med, Do, Andrea Roast, Md

Books, Presentations, Posters, Etc.

Introduction: Atypical HUS (aHUS) is a rare type of Thrombotic Microangiopathy distinguished by complement dysregulation and overall clinical progression. We present a diagnostically ambiguous case with early intervention that preserved end-organ function with discussion of future pregnancy implications. Case Presentation: A 36yo F (G2P1) with hypothyroidism, Small Intestinal Bacterial Overgrowth (SIBO), and intermittent urticarial rashes presented with fever, abdominal pain, and 3 days of bloody diarrhea. Discussion: This case highlights an atypical presentation of aHUS with diarrheal prodrome and normal complement function, features that typically suggest Shiga toxin–mediated HUS. We saw clinical change after admission, allowing real-time monitoring. Maintaining a …

Optimizing Behavioral Health Integration In Primary Care Through A Targeted Didactic, Ravneet Dhaliwal, M.A., Behavioral Health Intern, Joshua Morris

Books, Presentations, Posters, Etc.

Background: The integration of behavioral health into primary care settings is an essential strategy for improving patient outcomes, increasing access to mental health services, and achieving the Triple Aim of healthcare.1, 2 To maximize this integration and bridge the gap for primary care providers (PCPs), targeted didactic training and continued education are pivotal. National surveys indicate that PCPs often report low comfort levels in managing psychological concerns due to a lack of formal training, despite the high prevalence of these issues in primary care. 3, 4 Brief didactics facilitated by embedded behavioral health psychologists offer an accessible, adaptable method for …

Grace And Generosity: A Nt Defense Of Christian Giving And Stewardship, Jermaine Mcinnis

Masters Theses

This thesis holds that Christian stewardship and giving remain divinely appointed activities in the NT, despite growing skepticism in modern ecclesial and academic circles. Firmly grounded in biblical theology and canonical exegesis, the research argues that the disciplines of tithing, giving, and sacrificial stewardship are not eliminated by grace but are redirected and intensified with Christ. The research examines OT assumptions, Jesus’ instruction, and apostolic instruction to illustrate consistency in God's expectation of His people's obedience regarding finances. Drawing on current scholarship, the thesis refutes assumptions that giving is optional or less culturally relevant, underlining its vital importance to church …

The Sacrificial Vs. The Luzhinian Figure: Comparing Sacrificial Love In Crime And Punishment, Pride And Prejudice, And A Tale Of Two Cities, Natalie Rose Kubala

Masters Theses

Many works of art and literature exploring the theme of love focus on trying to define what love is; in contrast, this thesis dives deeper into defining what love is not, specifically focusing on the relationship between love and sacrifice. This thesis argues that love is not the same as sacrifice because a true sacrifice requires that love is already present prior to the sacrifice being made. This thesis will compare those who perform true sacrifices to those who perform sacrifices for their own personal gain by exploring grandiose narcissistic characters who perform (or attempt to perform) sacrifices without love …

Patient Follow-Ups For Hospital Nurses: Addressing Nurse Well-Being After Rapid Response Events, Quean Brown, Cristin Phillips, Molly Liddell, Katherine Thompson, Tala Fuad Hatem Abu Zahra, Jacqueline Christianson

Creating Healthy Work Environments (CHWE)

Background: Bedside registered nurses (BRNs) in the hospital setting care for patients who may unexpectedly deteriorate. When nurses witness patient deterioration, it is helpful for them to engage in meaning-making and contextualization to facilitate compassion satisfaction, mitigate secondary traumatic stress, and improve job satisfaction (Kopacz et al., 2019; Sattler & Smith, 2020). When a rapid response team (RRT) intervention is called and the patient warrants transfer to intensive care (ICU), BRNs rarely receive formal follow-up regarding the outcomes of their patients. Lack of feedback regarding critical situations may contribute to secondary traumatic stress, moral distress, decreased job satisfaction among BRNs, …

Comparing Nurse Well-Being Across The Career Trajectory: An Analysis Of The Healthynurse Survey, Alison F. Cuccia

Creating Healthy Work Environments (CHWE)

Background: Nurses face persistent challenges in maintain well-being (Lönnqvist et al., 2025; Priano et al., 2018), which may contribute to the nurse staffing crisis. This analysis examines differences in well-being among nurses in different stages of their career trajectory.

Methods: Data from the HealthyNurse survey collected June 2024-May 2025 were examined (n=5006). Outcomes included fatigue, anxiety, depression, social ability, and physical functioning, measured using Patient-Reported Outcome Measurement Information System short form scales. Moderate to vigorous physical activity (MVPA, minutes/week), days of strength training per week, the Healthy Eating Index, and BMI were also measured and used as outcomes. …

Medication Reconciliation In The Emergency Department: Whose Job Is It?, Courtney N. Loecker, Lori Gaver, Jadyn Brooks, Monica Hanus, Ally Smart

Creating Healthy Work Environments (CHWE)

Background: Medication reconciliation is a critical component of hospital admission, reducing medication errors, improving patient safety, and ensuring continuity of care.^1–3 Uncertainty persists over which healthcare providers (i.e., nurses, pharmacists, physicians) are primarily responsible for performing medication reconciliation when patients are admitted from the emergency department (ED).⁴ Understanding frontline nurses’ perspectives about medication reconciliation is key to informing practice improvements and patient outcomes.

Purpose: This project aimed to identify nurses' perspectives about current medication reconciliation practices including responsibility, barriers, and solutions to enhance safety, workflow efficiency, and interprofessional collaboration.

Methods: Guided by the Plan Do Study Act framework …

Barks And Beans: A Place To Enjoy Two Things You Love, Erika Davis

Honors Projects

This project explores the necessary steps that need to be taken in order to have a successful and impactful pet cafe. "Barks and Beans" is a pet cafe created to enhance the community and benefit societies mental health and social wellbeing while operating as a successful business. This project is guided by the research questions "How does integrating dogs into a coffee shop environment influence factors such as customer attraction, retention, and overall brand identity?” and “What impact do dogs in a coffee shop have on a customer's emotional/mental well-being, satisfaction of experience, and likelihood of returning?”. Given the research …

Judging A Book By Its Cover: Exploring Ethical Solutions For Marketing & Labeling Romance Novels With Illustrated Cover Art, Tricia Filbrun

Honors Projects

As social media platforms and subcommunities have driven massive sales for romance titles in the publishing industry, there has been an intense debate among literary communities, parents, and school administrators about whether the illustrated cover art style is appropriate. Some readers feel that these books are intentionally marketed towards a younger audience, and the sexually explicit nature of the content was not made clear, or labeled at all, before they read the book. This paper explores four likely marketing and labeling solutions that could be implemented to resolve this issue, and whether they are ethical by marketing and advertising standards, …

Mindful Tea Drinking As A Low-Cost Sensory Intervention For Reducing Stress In College Students, David Gabel

Honors Projects

The proposed study would investigate the effects of a tea-based sensory mindfulness exercise on stress in college aged participants. Participants would listen to a mindful tea exercise and a non-mindful tea exercise after a mild stress-inducing Stroop test. For both conditions, the participants would report their current state of distress on the Subjective Units of Distress Scale (SUDS) before and after each tea exercise and their heart rate variability (HRV) would be measured during each segment of the experiment.

Descriptive statistics and a paired samples t-test would be used to compare the mindful tea condition with the non-mindful condition following …

April 29, 2026 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Parents Of Students With Severe Autism Studying In Virtual Learning Environments And Their Perceptions And Experiences Working With School Administrators: A Hermeneutic Phenomenological Study, Shelli L. Allen

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study is to understand parents’ lived experiences and perceptions of their interactions with school administrators in virtual learning environments. The study centers on the following research question: What are the experiences of parents of children with severe autism as they work with school administrators in virtual learning environments? The hermeneutical framework guiding this study is Vygotsky’s Constructivist Learning Theory, which helps us understand learning through interaction, collaboration, and cognitive apprenticeship, with a focus on instructional practices that prioritize students’ cognitive development. The phenomenological design is to help the researcher to examine parents’ lived experiences …

Transcendental Phenomenological Study Of Christian Women’S Response To Their Spouses’ Pornography Use, Margaret Harris

Doctoral Dissertations and Projects

This transcendental phenomenological study explored the emotional responses Christian women experience upon discovering their spouse’s pornography use and how they perceive their spouse’s openness during and after disclosure. Guided by Husserl’s descriptive philosophy, the study used confidential Zoom interviews and a focus group with Christian women aged 18 and older to gather first‑person accounts of the phenomenon. Through phenomenological reduction, repeated readings, and the refinement and synthesis of meaning units, six superordinate themes emerged: faith as an Interpretive lens; pornography as a violation of relational, emotional, and moral boundaries; discovery as an emotional and relational turning point; communication as a …

Two Centuries Of Sexism In British Parliament: A Computational Analysis Of Women’S Representation In The Hansard Corpus, Mandira Sawkar

Theses

Detecting sexism and gender bias in text is a central problem in NLP, yet most existing work focuses on short, informal content such as social media posts. In contrast, much less is known about how sexism operates in long-form, formal discourse, where it is often expressed indirectly through rhetorical framing, appeals to tradition, or references to gender roles. Parliamentary debates offer a particularly rich setting for studying such language, but their scale, linguistic complexity, use of archaic English, and the presence of distributional shift across centuries make systematic analysis challenging and historically infeasible without automation. In this work, we analyse …

3d Infographic Animation Series Unleashing The Mechanism Of Disease (Mod) Of Ventricular Tachycardias In Cellular And Molecular Levels: Afterdepolarization Subtypes And Triggered Activity, Yan Ning ‘Harmony’ Wong

Theses

Ventricular arrhythmias (VAs) account for 75-80% of sudden cardiac deaths, causing 184,000 to 450,000 deaths annually in the U.S. VAs commonly occur in individuals with structural heart diseases, but idiopathic ventricular tachycardias (VTs) caused by delayed afterdepolarizations (DADs), early afterdepolarizations (EADs) and triggered activity, can also arise due to calcium ion discrepancies without apparent structural abnormalities. Despite advances in understanding abnormal impulse conduction, there is a paucity of visual aids that explain impulse formation anomalies of VTs. There are no 3D animations that link ECG interpretation to molecular dynamics in the cardiac EC coupling process. Moreover, ECG interpretation skills are …

2026-04-29 Seattle U Hui Ο Nani Hawai’I Hosts 64th Annual Lu’Au, Diego Dumlao

The Spectator Online

No abstract provided.

2026-04-29 Crisis Care Center Coming To Capitol Hill, Kean Mathis

The Spectator Online

No abstract provided.

Raising The Barb: Evaluation Of Phenobarbital Use For Alcohol Withdrawal In Patients On General Medicine Floors, Seth Arakawa, Jason Frederick, Anthony Le

Books, Presentations, Posters, Etc.

Abstract: Alcohol withdrawal syndrome (AWS) can present as a spectrum of symptoms such as a mild headache, gastrointestinal issues, and diaphoresis. However, if not treated properly, it can progress to severe hallucinations, seizures, or delirium tremens. Current guidelines from the American Society of Addiction Medicine (ASAM) recommend benzodiazepines as first line agents for alcohol withdrawal with phenobarbital recommended as an adjunct agent or replacement to benzodiazepines by providers who are familiar with its use. Although most evidence supporting phenobarbital in AWS comes from critical care settings, emerging data suggest it may also be safe and effective in general ward patients. …

An Exploration Of Drivers Of Sepsis Outcomes In Racial And Ethnic Minority Populations, Matthew Moritz, Omar Pandhair, Shelley Schoepflin Sanders

Books, Presentations, Posters, Etc.

RATIONALE: Race and ethnicity affect sepsis outcomes in unclear ways. Existing data is conflicting, with some studies suggesting minority patients do worse, while others did not show a difference in outcomes between these groups. We sought to investigate whether inequalities exist in sepsis outcomes for different racial and ethnic groups in our large hospital system and to characterize how they may manifest. METHODS: We performed a retrospective cohort study of adults diagnosed with sepsis and discharged from any of Providence’s 52 hospitals between January 1 and December 31, 2023. We grouped patients into ten different race/ethnicity groups including White, Black, …

A Rare And Fatal Complication Of Herpes Simplex Virus (Hsv) Infection, Natalie Bolton, Jeffrey Youker

Books, Presentations, Posters, Etc.

Introduction: Hemophagocytic Lymphohistiocytosis (HLH) is a rare syndrome characterized by overactive immune activation, cytokine storm, and uncontrolled hemophagocytosis. Primary HLH is familial and most often seen in infants, whereas secondary HLH occurs more frequently in adults and is triggered by infections, malignancies, or autoimmune disorders. Clinically, secondary HLH often mimics sepsis but fails to respond to standard therapies, contributing to delayed diagnosis and treatment. Without timely intervention, HLH can result in extensive tissue damage, multiorgan failure, and death. In rare cases, central nervous system (CNS) involvement may occur, manifesting as histiocytic infiltration that can be misinterpreted as malignancy or infection. …

Behavior Change In A Young Woman: The Secret Lies In The Ovarian Tumor, Matthew Moritz, Md, Linh Tang Taylor, Md, Olivia L Snir, Stephanie Griffith, Md

Books, Presentations, Posters, Etc.

Introduction: Autoimmune encephalitis is a rare immune-mediated disorder characterized by neuropsychiatric symptoms. Anti-NMDA receptor (NMDA-R) encephalitis, the most common subtype, affects approximately 1 in 1.5 million people annually. We present a case of a young female with new-onset hallucinations, behavioral changes, and personality disturbance. Case Presentation: A 32-year-old female with remote methamphetamine use and recent trauma presented with acute mental status changes, aggression, emotional lability, and hallucinations. Vitals were normal; on exam she appeared confused, agitated, and displayed unusual behavior, including hallucinations. Initial evaluation revealed mild leukocytosis, but otherwise normal urine drug screen, chest radiograph, TSH, ANA, VDRL, heavy metal …

Cloudy Consequences: Exploring Vaping-Induced Pulmonary Alveolar Proteinosis, Jennifer Wong, Do, Omar Pandhair, Abby Lindseth, Md, Cameron Miles Long, Md

Books, Presentations, Posters, Etc.

Abstract: Pulmonary alveolar proteinosis (PAP) is a rare disease caused by abnormal accumulation of surfactant within alveoli. Vaping of electronic cigarette smoke has recently been described as a cause of pulmonary alveolar proteinosis in two case reports. We add to this rare literature by describing a case of pulmonary alveolar proteinosis induced from vaping in a young woman with confirmed granulocyte/macrophage colony-stimulating factor (GM-CSF) autoantibodies as the proposed mechanism. Introduction: Pulmonary alveolar proteinosis (PAP) results from inappropriate accumulation of pulmonary alveolar surfactant due to dysregulated granulocyte/ macrophage colony-stimulating factor (GM-CSF) signaling.1 Its incidence is approximately 0.2 cases per million with …

Ecmo As A Bridge To Lung Transplant For Refractory Rapidly Progressive Interstitial Lung Disease, Matthew Moritz, Omar Pandhair

Books, Presentations, Posters, Etc.

Anti-melanoma differentiation-associated gene 5 (MDA-5) antibody is most frequently associated with dermatomyositis with various degrees of clinical manifestations including rapidly progressive interstitial lung disease (RP-ILD), inflammatory arthritis, vasculopathy, and other cutaneous findings. Clinically amyopathic dermatomyositis (CADM) is frequently associated with RP-ILD and has high mortality rates. Here we present a case of anti-MDA5 associated RPILD but without other features of dermatomyositis that did not respond to standard immunosuppressive therapy. A 41-year-old woman with recently diagnosed interstitial lung disease and polyarthritis previously on methotrexate presented with progressive dyspnea and worsening hypoxemic respiratory failure. She was previously admitted for respiratory failure two …