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A Border Of Broken Promises: The Unfulfilled Commitments Of The Crc For Migrant Children At The U.S. Southern Border, Eva R. Passer

Honors Scholar Theses

This thesis examines how closely the treatment of migrant children from Latin America to the United States aligns with the ideals of the United Nations Convention on the Rights of the Child (CRC). Its central question is: to what extent do current practices comply with CRC standards? Although the CRC outlines clear obligations to uphold the best interests and fundamental rights of all children, these principles are inconsistently applied within U.S. immigration policy and practice. Through a comparative analysis of Donald Trump’s first administration and Joe Biden's presidential administration, this thesis evaluates six CRC articles concerning child migrants. It then …

Identifying And Quantifying The Presence And Benefits Of Natural Products In Commonly Consumed Herbs, Fruits, And Teas, Angelica Velasquez

Honors Scholar Theses

Natural products are primary or secondary metabolites derived from plants, animals, or microorganisms that display bioactive properties which can be beneficial to human health. Such properties include antibiotic, anticancer, antioxidant, anti-inflammatory, and may play a role in drug discovery. These compounds can be isolated and synthetically altered to enhance their therapeutic potential. However, isolating individual compounds from natural sources is often challenging due to their low abundances. Gas chromatography-mass spectrometry (GC-MS) enables the detection of trace-level metabolites, making it an indispensable tool in the screening process. In this study, GC-MS was utilized to identify and quantify natural compounds in 12 …

Technical Debt Amplified By Ai: Real-World Case Studies And Strategies For Mitigation, Alejandro L. Reilly

Honors Scholar Theses

Artificial intelligence (AI) is a powerful tool that can help accelerate the accumulation of software debt, but it also provides the tools needed to manage and reduce that same burden. In this paper, we discuss the impact of AI-powered code tools on technical debt, as well as how these tools can be used to assist developers in their current practices. We also discuss some of the challenges that can arise when developers accept AI-generated code without going through the best practices of software engineering. The case studies in this paper show that the path to sustainable software in the era …

The Development Of A Crispr-Based Calibrated Functional Assay For Classifying Pathogenicity Of Msh2 And Msh6 Variants In Lynch Syndrome, Olivia N. Amodeo

Honors Scholar Theses

Lynch syndrome is a hereditary disease caused by the inheritance of a mismatch repair gene variant. Individuals with this condition are predisposed to cancer development, most commonly colorectal cancer. Current guidelines for variant classification are based on numerous evidence categories, including functional evidence. However, many novel clinical variants are not well characterized, and evidence is difficult to obtain if functional assays are not calibrated.

To address this, our lab created a calibrated functional assay that calculates an odds of pathogenicity score for MSH2 and MSH6 gene variants that can be used as evidence for classifying variants of uncertain significance. This …

Reversible, Light-Controlled Inhibition Of Stim1-Mediated Calcium Signaling Using Photoswitchable Ml-9 Derivatives In Jurkat-Lucia Nfat Reporter T Cells, José L. Matute Gálvez

Honors Scholar Theses

Store-operated calcium entry (SOCE) through calcium release-activated

calcium (CRAC) channels is the dominant pathway for sustained Ca2+ influx in

non-excitable cells and is essential for T cell activation, driving downstream

signaling through the calcineurin-NFAT transcriptional axis. Dysregulation of

SOCE produces multi-systemic disease phenotypes, establishing that precise,

spatiotemporally controlled modulation of this pathway is a fundamental

therapeutic requirement. ML-9 is one of the only characterized small molecules

capable of targeting SOCE upstream at the level of STIM1 localization, but lacks

the selectivity, pharmacokinetic properties, and spatiotemporal control necessary

for therapeutic development.

This work describes the design, synthesis, and biological evaluation of …

Disturbances In A Convergece Zone: Artisanal Fishers And The Making Of The Nearshore In Northern Coastal Peru, Leigh Shattuck Rodi

Electronic Theses and Dissertations

This project seeks to study how artisanal fishers in northern coastal Peru interpret and respond to environmental change provoked by three sources of harm: climate change, overfishing, and contamination. Drawing from six and a half weeks of ethnographic fieldwork among artisanal fishers in Lobitos, Peru, this paper foregrounds the concept of the nearshore assemblage to highlight the ever-shifting relations between humans and marine ecologies that constitute littoral and oceanic worlds. Artisanal fishers utilize discriminatory, non-mechanical methods to fish in a protected section of Peru’s Exclusive Economic Zone (EEZ). Fishing livelihoods in this space were previously possible because the convergence of …

Health And Care: Childhood Among The Classic Period Maya At Buenavista Del Cayo, Belize, Lindsey Hall

Electronic Theses and Dissertations

Three deposits of perinates, infants, and young children within two non-residential superstructures of Buenavista del Cayo, Belize, display evidence of daily maintenance and care. A total of ten subadult individuals, aged 39.4 weeks gestation to 3 years, from the archaeological site of Buenavista were recovered during 2018 excavations. Signs of care and daily maintenance include survivorship through the vulnerable neonatal period (first twenty-eight days) and transition into infancy, survivorship with potential pinprick lesions on external and internal zygomatic, parietal, and pars basilaris, and intentional maintenance of the body after death. Identification of care and daily maintenance at Buenavista informs the …

Mining The Body: Racial Capitalism And The Embodied Sacrifice Zone, Regina Marie Young

Electronic Theses and Dissertations

Mining the Body: Racial Capitalism and the Sacrifice Zone of the Body examines 20th and 21st-century American literature, excavating the ways in which mining not only extracted resources from the earth, but also mined the bodies of their workers for their labor, often ignoring safety in the name of economy. This extraction of coal and of labor, along with its attendant exploitations, sparked unionization and labor movements throughout the century, as miners were frequently at the forefront of asserting their rights in response to this treatment. Using a framework that relies on both environmental criticism, such as Rob Nixon’s Slow …

Examining The Relationship Between Co-Curricular Programming And Burnout Among Medical Students At An Academic Medical Center, Lauren Williams

Electronic Theses and Dissertations

This three-manuscript dissertation examines the relationship between co-curricular programming and burnout among Doctor of Medicine (MD) students at the University of Mississippi Medical Center (UMMC), situating the issue within broader concerns about physician well-being and institutional responsibility.

Manuscript I establishes the conceptual and empirical foundation for the study by reviewing the prevalence, consequences, and theoretical framing of burnout in medical education. Drawing on Maslach’s three-dimensional model of burnout—emotional exhaustion, depersonalization, and reduced personal accomplishment—and Astin’s Student Involvement Theory, the manuscript situates co-curricular engagement as a potential protective factor against distress. The literature review highlights alarming rates of depression, suicidal ideation, …

Right (Or Wrong) To Bear Arms: Regional-Campus Women Students' Perceptions Of Campus Carry, Daniel Christian

Electronic Theses and Dissertations

Campus carry legislation remains one of the most contested higher education policy issues in the United States, particularly in states where concealed carry permit holders may legally carry firearms on public college campuses. Although prior research has included women as one of many demographics, there is a dearth of scholarship that focuses on college women exclusively to investigate their response to campus carry. This gap is concerning given documented gender differences in attitudes toward gun policy and the disproportionate impact of sexual violence and safety concerns on women in collegiate settings.

To fill a gap in the literature, the proposed …

A Needs Assessment For College Students Of Incarcerated Parents (Csips), Deetra A. Wiley

Electronic Theses and Dissertations

The presence and needs of children of incarcerated parents are largely invisible within higher education, even though they experience a variety of adverse social, emotional, and academic outcomes. A population that navigates complex trauma, financial instability, stigma, and institutional neglect with limited support is the focus of this dissertation in practice (DiP): College Students of Incarcerated Parents (CSIPS). This manuscript assesses the availability of institutional services and examines the academic challenges faced by CSIPS, as guided by the Advocacy Strategy Framework (Kozleski, 2010). A thorough examination of the literature has revealed that a sense of belonging and academic persistence are …

Exploring Academic Support And Motivation Among Current And Prospective Adult Learners In Mississippi Pursuing A Diploma Through The University Of Mississippi Online High School Program, Reham Helal

Electronic Theses and Dissertations

This qualitative study examined the academic support systems and motivational factors influencing adult learners in Mississippi who are enrolled in or consider enrollment in the University of Mississippi High School (UMHS) online diploma program. Grounded in Self-Determination Theory (Deci & Ryan, 2000), the research examined how autonomy, capability, and connection influence adult learners’ motivation to return to and persist in education after periods of interruption.

By conducting semi-structured interviews with five adult learners aged 27 to 51, the study revealed the real-life experiences and challenges that shape their educational journeys. The findings showed that participants’ initial withdrawals from high school …

School Counselor Preparation For Supporting Special Education Competencies In Mississippi, Rachel Mcclain

Electronic Theses and Dissertations

School counselors play a critical role in supporting the academic, social, emotional, and career development of students with disabilities (SWD) in K-12 educational settings. However, current preparation standards provide limited guidance regarding how school counseling programs should prepare school counselors-in-training to work with special education populations. This qualitative case study explored how two CACREP-accredited school counseling programs in Mississippi prepare school counselors-in-training to support SWD. Participants included school counselor educators, site supervisors, and school counseling interns affiliated with the programs. Data were collected through semi-structured interviews and a document review of course syllabi and analyzed using thematic analysis. Findings revealed …

Invisible: An Autoethnographic Study Of Teaching And Learning With Physical Disabilities And Neurodivergence, Amanda Josephine Austin Goodwin

Electronic Theses and Dissertations

In this autoethnographic study, vignettes of a female high school teacher and graduate student with invisible disabilities are analyzed through the lens of Critical Disability Theory. This study provides teachers, administrators, and policy makers with a first-hand account of some of the barriers individuals with invisible disabilities face. Policies, environments, and practices in K-12 education, higher education, and broader society are analyzed. Advancements in inclusivity and accessibility as well as improvements in teacher education programs are suggested. Reflection throughout this study, three core themes emerged: listen, believe, and support individuals with invisible disabilities.

Exploring Integrated Arts Education For Students With Autism, Karen Denise Harrison

Electronic Theses and Dissertations

Students with autism spectrum disorder (ASD) are often misunderstood because of challenges in communication, social-emotional development, and sensory processing. Neuroscience research highlights that individuals with ASD process information and stimuli differently, particularly in areas related to sensory integration, executive functioning, and emotional regulation. Traditional educational methods often isolate these students from their neurotypical peers, reducing opportunities to engage meaningfully with standards-based curricula. Integrated arts education offers an alternative approach, aligning with neuroscience principles by engaging multiple brain regions through movement, rhythm, imagery, and creativity, allowing students with ASD to demonstrate their learning through project-based and creative experiences that meet diverse …

Faculty Socialization In Physical Therapy Residencies, Joseph Michael Meurrier

Electronic Theses and Dissertations

Therapy schools. Many of the new faculty members will be composed of former clinicians who have made the transition to academia without any prior preparation or experience in the academic sphere. To help with this transition, the American Physical Therapy Association (APTA) has accredited Faculty Development Residencies (FDRs) to help prepare new faculty for academic life. However, many clinicians transitioning to faculty life are not in a position to go through a residency prior to starting an academic position. Therefore, my goal with the Dissertation in Practice (DiP) was to take the socialization elements from the FDRs and propose a …

Young Alumni Engagement At The University Of Mississippi: A Qualitative Study On Recent Graduate Perceptions Of The Ole Miss Alumni Association, Mary Kate Skelton

Electronic Theses and Dissertations

Declining government funding for higher education has led universities to progressively rely on private donations from alumni and donors. Mississippi’s budget for higher education has decreased by $6.6 billion from FY08 to FY18 (Mitchell et al., 2019). As financial pressure increases, the role of alumni association offices has become crucial in securing financial support for scholarships, infrastructure, research, and campus life (McDonough, 2017). With alumni contributing over $59.9 billion in private funds to higher education in 2022, their support is vital for colleges and universities to meet financial and academic goals (CASE, 2023). Early engagement of young alumni is critical …

Exploring Mississippi Valley State University’S First-Year Experience Program: Students’ Perceptions Of Its Impact On Their Sense Of Belonging, Jordan Freeman

Electronic Theses and Dissertations

Colleges and universities have a primary goal of providing quality education to their students with the hope that those students go on to make positive contributions to society. While many people tend to credit classroom learning for those societal contributions, an argument can be made that supplementary experiences are just as valuable. At Mississippi Valley State University (MVSU), a small, public Historically Black College/University in the Mississippi Delta area, student engagement initiatives are of extreme importance for first-year students. Students at MVSU face several challenges including college readiness, ability to afford college, and desire to persist and earn their degrees. …

Could Grange Membership Reduce Brain Drain?: Perceptions Of Student Fraternal Members On Returning To Rural America After Graduation, Amanda Leigh Brozana

Electronic Theses and Dissertations

Rural communities across the United States continue to experience population decline as young adults with postsecondary aspirations often leave their hometowns in pursuit of educational and economic opportunities. This migration, commonly referred to as rural brain drain, is often a result of the cumulative effects of limited access to postsecondary resources, career pathways, and community infrastructure that support rural retention. While extensive research documents the economic and educational dimensions of this phenomenon, fewer studies explore the influence of social, civic, and fraternal organizations on sustaining rural identity and fostering connection to place. This Dissertation in Practice proposes a study to …

Life Balance And Teacher Wellness: Exploring Protective Factors Among Early Childhood Educators, Kathryn Amidon

Electronic Theses and Dissertations

Early childhood educators shape future generations by guiding the development of young children. The well-being of early childhood educators is a concern due to unique stressors within the early childhood education context, including heavy workloads, high demands, and too few resources. Previous studies on the topic of teacher wellness have shown that teachers’ mental wellness impacts teacher burnout, teacher retention, and student outcomes, making the need for better understanding of the factors influencing teacher wellness a priority for future research. This quantitative study aimed to explore life balance as a protective factor of teacher wellness, inquiring about the extent of …

The Impact Of County School Zone Policies On Retention And Racial Composition In Schools: A Study Of Florida's Ten Largest Urban School Districts, Jazanae Alize Humphries

Electronic Theses and Dissertations

This study explores how zoning policies contribute to academic disparities in Florida’s Ten largest urban school districts. This study selected Florida because it operates a large public school system with diverse urban districts that enforce geographic assignment policies within shared statewide policies. These districts serve large populations, manage substantial demographic inequality, and rely heavily on boundary based school assignment, making them significantly important to examine zoning governance in education. To better understand this for Florida districts is significantly important as there is limited research on how zoning policies are enforced across large districts, which serve the majority of urban black …

Institutional Strain And Substance Coping: Analyzing Perceived Racial Discrimination As A Predictor Of Adolescent Marijuana Use, Fahad Bin Islam Khan

Electronic Theses and Dissertations

This study examines the relationship between perceived racial/ethnic discrimination, psychological distress, and youth marijuana consumption through the lens of the General Strain Theory. It uses the complete-case sample from the 2023 Youth Risk Behavior Survey (YRBS), which surveyed 17,268 high school students across the United States, in a cross-sectional study. The study used logistic regression analyses to assess the association between perceived racial or ethnic bias (e.g., actual discriminatory experiences), psychological distress, and substance use (marijuana), and how closely emotional stress linked these two phenomena. The results indicate that perceived discrimination has a significant positive association (greater likelihood) with both …

Investigating The Effects Of High- And Low-Load Resistance Training On Tendon Size, Muscle Growth, And Strength Adaptations, William Blake Hammert

Electronic Theses and Dissertations

Purpose: To examine the effects of resistance training load and a single bout of maximal strength testing on skeletal muscle growth, distal biceps brachii tendon thickness, and task-specific and non-specific strength outcomes relative to a time-matched non-exercise control group. Methods: 216 young (~21 years), non-resistance trained adults (125 females) were enrolled, with 201 (118 females) included in the final analyses. Participants were randomized to: High-Load (n=45), Low-Load (n=48), Mid-Point (n=54), or Control (n=54). High- and Low-Load completed 6 weeks of unilateral elbow flexion resistance training to task failure, Mid-Point completed a one-repetition maximum (1RM) elbow flexion test at 3-weeks, and …

Adversarial Llm-Gans For Robust Synthetic Pharmaceutical Data In Self-Emulsifying Drug Delivery Systems, Samiul Islam Niloy

Electronic Theses and Dissertations

The formulation of self-emulsifying drug delivery systems (SEDDS) represents a pivotal advancement in improving the oral bio-availability of poorly water-soluble pharmaceutical compounds, yet traditional development is heavily hindered by limited experimental datasets and the complexity of predicting key quality attributes like nanoparticle size and drug release profiles. Because empirical methodologies struggle to balance formulation constraints with predictive accuracy, this research introduces a comprehensive framework that leverages state-of-the-art generative artificial intelligence to synthesize realistic, constraint-compliant SEDDS datasets. The study proposes two primary methodologies to overcome data scarcity: a novel Drug Formulation Agent (DFA) powered by Large Language Models (LLMs) and a …

A Framing Analysis Of The Uvalde School Shooting In Two National Newspapers, S M Shams Rahman

Electronic Theses and Dissertations

This study investigates the media framing of the May 24, 2022, shooting at the Robb Elementary School in Uvalde, Texas, by comparing the coverage of two national newspapers, The Washington Post and The New York Times. Using the spatial-temporal scheme provided by Chyi & McCombs (2004), this study conducted a quantitative content analysis of 241 samples from a month’s coverage of the event in the two newspapers. The study attempted to identify whether there was any difference in the use of spatial, temporal, and spatial-temporal combination frames between the two newspapers, and whether there were any significant frame-changing patterns in …

Development And Evaluation Of Ros-Responsive Thioketal-Capped Mesoporous Silica Nanoparticles For Dual Drug Delivery Of Moxifloxacin And Curcumin In Wound Healing, Saiganesh Pothuraju

Electronic Theses and Dissertations

Chronic infected wounds remain a major clinical challenge because elevated reactive oxygen species (ROS) in the wound microenvironment sustain inflammation, damage regenerating tissue, and limit the effectiveness of conventional antimicrobial and anti-inflammatory therapy. To address this problem, this study aimed to develop ROS-responsive thioketal-capped mesoporous silica nanoparticles (TK-MSNs) for the dual delivery of moxifloxacin (MOX) and curcumin (CUR) to support the management of infected wounds. Mesoporous silica nanoparticles (MSNs) were synthesised using tetraethyl orthosilicate (TEOS) and cetyltrimethylammonium bromide (CTAB), followed by template removal, amino-functionalization with 3-aminopropyltriethoxysilane (APTES), and sequential loading of MOX and CUR. ROS-responsive capping was then achieved using …

The Unreliable Narrator: Mnemic Causation And The Reconstructive Self, Phuong Le

Electronic Theses and Dissertations

The purpose of this study was to investigate secondary-level band directors’ perception of preparedness to teach learners with exceptional needs in Mississippi. The study examined college and university music curricula to identify the number of courses that prepare future music educators to teach learners with exceptional needs. The researcher developed a survey that included questions about respondents' years and types of teaching experience, educational preparation in exceptional education, the level of instructional support available for accommodating students in band classes, and the impact disabilities have on learning and performance in instrumental music. Findings provided insight into how well pre-service and …

Open For Victims, Sorry We're Dead, Sela Ricketts

Electronic Theses and Dissertations

This thesis is a documentary exploration of paranormal tourism in the French Quarter neighborhood of New Orleans. As of completing this project, paranormal tourism is relatively new to the city, starting in earnest in the late 1990s and early 2000s. This niche industry has woven itself into the larger New Orleans tourism industry and drastically changed the landscape and popular identity of the French Quarter. The photos give a personal perspective of how the industry manifested within the city.

The throughline of this project is a feedback loop I identified- a cycle of influences that has ultimately made the French …

Recipe For Resistance: Oral Histories Of Queer Foodways In The Us South, Astrid Janie Knox-Mcconnell

Electronic Theses and Dissertations

This thesis examines the emerging question of what constitutes “queer food.” It asks how this concept takes on a distinct regional form in the United States South. Drawing on oral histories, archival materials, and cookbooks, it argues that queer southern foodways are not only a subset of queer food studies, but also a distinct cultural and political formation shaped by southern histories of race, labor, family, and survival. The thesis makes the case that queer southern foodways function simultaneously as protest, utopian practice, and aesthetic pleasure. Through the act of cooking, eating, and sharing food, queer southerners articulate alternative social …

The Impact Of An Adult-Focused First-Year Seminar On Tennessee Reconnect Students, Marci R. Reiter

Masters Theses and Doctoral Dissertations

The state of Tennessee launched a promise program entitled Tennessee Reconnect (TnR) in the Fall of 2018, which was aimed at the state’s adult learner population and offered a solution for affordable education. With this introduction came pressure for institutions, specifically community colleges in the state, to increase the retention and completion rates of this population of students. One small, rural community college approached this challenge by offering both first-time and returning adult learners an adult-focused First-Year Seminar (FYS) course. The course, entitled Work-Based Learning Seminar (WBLS), looked to assist with not only the retention and completion issues of the …