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Cross-Cultural Preferences For Women’S Waist To Hip Ratio And Men’S Shoulder To Hip Ratio: Data From Iran, Norway, Poland, And Russia, Farid Pazhoohi, Reza Afhami, Razieh Chegeni, Dmitrii Dubrov, Katarzyna Gałasińska, Ray Garza, Nasim Ghahraman Moharrampour, Dmitry Grigoryev, Marta Kowal, Ståle Pallesen, Gerit Pfuhl

School of Psychology

Objectives: Body size and shape are sexually dimorphic in humans, with men being characterized with larger upper bodies, while women typically having broader pelvises. Such sexually dimorphic traits, quantified as shoulder to hip ratio (SHR) in men and waist to hip ratio (WHR) in women, serve as cues of an individual’s genetic fitness, reproductive potential, health, and resource holding power, and, thereby, functioning as attractiveness cues to the opposite sex. Methods: In the current study, we investigated men’s and women’s preference for the opposite sex body shape (WHR in women and SHR in men) in samples from Iran, Norway, Poland, …

Faculty Senate Executive Committee Minutes January 22, 2024, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Call to Order - Maureen Hearns
• University Business - Elizabeth Cantwell, President | Larry Smith, Provost
• Faculty Senate Business - Maureen Hearns | John Ferguson | Grant Cardon
• Information
• Reports
• Old Business
• New Business
• Adjourn: 4:50 pm

Faculty Senate Executive Committee Agenda January 22, 2024, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• 3:30 Call to Order
• Approval of Minutes - December 11, 2023
• 3:35 University Business
• 3:50 Faculty Senate Business
• 4:00 Information
• Education Policies Committee
• Policy 200: Executive Summary
• Policy 382: Time and Attendance
• Policy 326
• 4:25 Reports
• Honorary Degrees and Awards
• Office of Research Annual Report
• PRPC Annual Report
• School of Graduate Studies Annual Report
• 4:45 Old Business
• 4:50 New Business
• Adjourn: 5:00 pm

Sigma Leverages Protein Structural Information To Predict The Pathogenicity Of Missense Variants, Hengqiang Zhao, Huakang Du, Sen Zhao, Zefu Chen, Yaqi Li, Kexin Xu, Bowen Liu, Xi Cheng, Wen Wen, Guozhuang Li, Guilin Chen, Zhengye Zhao, Guixing Qiu, Deciphering Disorders Involving Scoliosis & Comorbidities (Disco) Study, Pengfei Liu, Terry Jianguo Zhang, Zhihong Wu, Nan Wu

Faculty, Staff and Students Publications

Leveraging protein structural information to evaluate pathogenicity has been hindered by the scarcity of experimentally determined 3D protein. With the aid of AlphaFold2 predictions, we developed the structure-informed genetic missense mutation assessor (SIGMA) to predict missense variant pathogenicity. In comparison with existing predictors across labeled variant datasets and experimental datasets, SIGMA demonstrates superior performance in predicting missense variant pathogenicity (AUC = 0.933). We found that the relative solvent accessibility of the mutated residue contributed greatly to the predictive ability of SIGMA. We further explored combining SIGMA with other top-tier predictors to create SIGMA+, proving highly effective for variant pathogenicity prediction …

A New Perspective On Intervertebral Disc Calcification-From Bench To Bedside, Emanuel Novais, Rajkishen Narayanan, Jose Canseco, Koen Van De Wetering, Christopher Kepler, Alan Hilibrand, Alex Vaccaro, Makarand Risbud

Department of Orthopaedic Surgery Faculty Papers

Disc degeneration primarily contributes to chronic low back and neck pain. Consequently, there is an urgent need to understand the spectrum of disc degeneration phenotypes such as fibrosis, ectopic calcification, herniation, or mixed phenotypes. Amongst these phenotypes, disc calcification is the least studied. Ectopic calcification, by definition, is the pathological mineralization of soft tissues, widely studied in the context of conditions that afflict vasculature, skin, and cartilage. Clinically, disc calcification is associated with poor surgical outcomes and back pain refractory to conservative treatment. It is frequently seen as a consequence of disc aging and progressive degeneration but exhibits unique molecular …

How To Destroy The Liberal International Order, Bryan H. Druzin

Duke Journal of Comparative & International Law

This Article argues that a policy of containment directed at China could have disastrous consequences on the stability of the global system. The liberal international order, created to promote international coordination and structure global trade, comprises key institutions such as the United Nations, the World Trade Organization, the International Monetary Fund, and the World Bank. It is possible that much of the strength of these institutions stems from the fact that nations are "locked" into them simply because they are the only game in town. Put another way, the liberal order is, for lack of a better word, a "monopoly." …

Sleep Attitudes As An Indirect Predictor Of Risk For Metabolic Syndrome In First Year College Students, Sophie Hirsch, Hannah Peach, Trudy L. Moore-Harrison, Philip Zendels, Aria Ruggiero, Jane F. Gaultney

Journal of Social, Behavioral, and Health Sciences

Background: Habit formation can be a challenge for first-year students. Research has suggested that regardless of sleep knowledge, favorable sleep attitudes predict better sleep.

Aim: Our aim was to investigate whether sleep attitudes directly or indirectly predicted risk for metabolic syndrome via sleep.

Method: Students completed self-report and physiological measures. Participants wore wristwatches to collect sleep data. Path analyses investigated the direct or indirect effect of sleep attitude on risk for metabolic syndrome via subjective sleep (sleep quality, duration, risk for apnea) and objective sleep (sleep efficiency, duration, subjective risk for apnea).

Results: In our subjective analysis that sleep attitudes …

Barriers To Video Laryngoscopy In Low-Middle Incomes Countries, Mason Easterling, Mary Beth Greenway

Group: Samford University Moffett & Sanders School of Nursing

The patient in this case study presented to a rural surgical clinic in Guatemala for surgery with characteristics of a probable difficult airway. In the United States, anesthesia providers will often use a video laryngoscope (VL) to manage an expected difficult airway requiring an endotracheal tube. However, many barriers exist towards this technology being adopted as common practice in low-middle income countries (LMICs) like Guatemala. These barriers include financial resources, education, and training. Thankfully, the Air Angel Project, a medical nonprofit, has designed the AirAngel Blade: a 3D printed VL blade equipped for use with a commercially available endoscope and …

“Resulting From” Unclear Language: Why Congress Must Amend The Anti-Kickback Statute To Clarify Its Intent To Hold Violators Accountable And Recover Fraud-Based Payments, Lauren Rutkowski

Seton Hall Law Review

No abstract provided.

Fusionnw, A Potential Clinical Impact Assessment Of Kinases In Pan-Cancer Fusion Gene Network, Chengyuan Yang, Himansu Kumar, Pora Kim

Faculty, Staff and Student Publications

Kinase fusion genes are the most active fusion gene group in human cancer fusion genes. To help choose the clinically significant kinase so that the cancer patients that have fusion genes can be better diagnosed, we need a metric to infer the assessment of kinases in pan-cancer fusion genes rather than relying on the sample frequency expressed fusion genes. Most of all, multiple studies assessed human kinases as the drug targets using multiple types of genomic and clinical information, but none used the kinase fusion genes in their study. The assessment studies of kinase without kinase fusion gene events can …

The Rider (2024-01-22), Natalie Lapsley

The Rider Archives

Vol.9 No.16

When To Marry, If At All?A Qualitative Exploration Of How Sexual Minority Young Adults In The Us Think About Marital Timing, Aaron Hoy, Sachita Pokhrel

The Qualitative Report

According to prior research, the average age at first marriage has steadily increased in the US due in large part to the significance that young adults place on marriage and their evolving conceptions of marital readiness. However, despite the nationwide legalization of same-sex marriage in 2015, there is a significant oversight of sexual minorities in this research. To address this, we draw upon qualitative data collected through an online survey to explore how our sample of unmarried sexual minority young adults (N=256) think about marital timing. The results of our thematic analysis show that those in our sample …

Consideration Of Ameliorative Measures In International Child Abduction Cases Post-Golan, Stephanie L. Tang

Seton Hall Law Review

No abstract provided.

Solitary Confinement In Sheep’S Clothing: The Unlawfulness Of Medical Isolation Protocols During The Covid-19 Pandemic In American Prisons, Alexandra Franchino

Seton Hall Law Review

No abstract provided.

A Blurry Lens: Assessing The Complicated Legal Landscape Of Biometric Privacy Through The Perspective Of Mobile Apps, Mackenzie K. Mendolla

Seton Hall Law Review

No abstract provided.

Cross-Sectional And Descriptive Study On The Challenges And Awareness Of Hispanic Parents Regarding Their Adolescents’ Mental Health During The Covid-19 Pandemic, Jihye Kim, Robin Scott

Faculty Articles

Research has shown that during the COVID-19 pandemic, approximately 20% of children and adolescents in the United States experienced mental health issues that became a significant social concern. However, recent studies have demonstrated that the majority of adolescents maintain positive emotions despite the crisis. This cross-sectional and descriptive study delves into the emotional states of adolescents during the pandemic, considering the viewpoints of both adolescents and their parents, with a specific focus on Hispanic adolescents. Survey results revealed that most adolescents reported positive and happy moods. However, a percentage of adolescents experienced worry, significant changes in feelings, and loneliness as …

Self-Renewing Human Naïve Pluripotent Stem Cells Dedifferentiate In 3d Culture And Form Blastoids Spontaneously, Mingyue Guo, Jinyi Wu, Chuanxin Chen, Xinggu Wang, An Gong, Wei Guan, Rowan M Karvas, Kexin Wang, Mingwei Min, Yixuan Wang, Thorold W Theunissen, Shaorong Gao, José C R Silva

2020-Current year OA Pubs

Human naïve pluripotent stem cells (hnPSCs) can generate integrated models of blastocysts termed blastoids upon switch to inductive medium. However, the underlying mechanisms remain obscure. Here we report that self-renewing hnPSCs spontaneously and efficiently give rise to blastoids upon three dimensional (3D) suspension culture. The spontaneous blastoids mimic early stage human blastocysts in terms of structure, size, and transcriptome characteristics and are capable of progressing to post-implantation stages. This property is conferred by the glycogen synthase kinase-3 (GSK3) signalling inhibitor IM-12 present in 5iLAF self-renewing medium. IM-12 upregulates oxidative phosphorylation-associated genes that underly the capacity of hnPSCs to generate blastoids …

Microglia-Derived Exosomes Modulate Myelin Regeneration Via Mir-615-5p/Myrf Axis, Xiao-Yu Ji, Yu-Xin Guo, Li-Bin Wang, Wen-Cheng Wu, Jia-Qi Wang, Jin He, Rui Gao, Javad Rasouli, Meng-Yuan Gao, Zhen-Hai Wang, Dan Xiao, Wei-Feng Zhang, Bogoljub Ciric, Yuan Zhang, Xing Li

Department of Neurology Faculty Papers

Demyelination and failure of remyelination in the central nervous system (CNS) characterize a number of neurological disorders. Spontaneous remyelination in demyelinating diseases is limited, as oligodendrocyte precursor cells (OPCs), which are often present in demyelinated lesions in abundance, mostly fail to differentiate into oligodendrocytes, the myelinating cells in the CNS. In addition to OPCs, the lesions are assembled numbers of activated resident microglia/infiltrated macrophages; however, the mechanisms and potential role of interactions between the microglia/macrophages and OPCs are poorly understood. Here, we generated a transcriptional profile of exosomes from activated microglia, and found that miR-615-5p was elevated. miR-615-5p bound to …

Thermal Runaway Analysis And Cooling Strategies For Nmc 523 Li-Ion Battery Packs Using Pcm, Heat Pipes, And Air Cooling, Vijethvardhan Singh

Master's Theses

The growing demand for electric vehicles (EVs) necessitates efficient thermal management of lithium-ion batteries (LIBs), especially NMC 523 cells. This thesis investigates thermal runaway (TR) mechanisms and evaluates cooling strategies to mitigate overheating risks. Using ANSYS Fluent, the TR of four cells in series was simulated and validated with Jun Wu et al.'s experimental data, achieving an error margin below 10%. Peak temperatures reached 1,126°C in the first cell, with delayed propagation in adjacent cells. Sensitivity analysis of voltage, current, and state of charge (SOC) under varying C-rates was performed using a multi-scale multi-domain (MSMD) battery model. A logarithmic voltage …

Incubating Education: The Lived Experiences Of Louisiana Elementary And Middle School Teachers When Piloting A 4-H Stem School Enrichment Curriculum, Crystal Rose Ahrens

LSU Doctoral Dissertations

This study addressed a deficiency in the agricultural literacy of the U.S. population by focusing on the challenges that core subject teachers face when integrating agriculture into their curriculum. Using a phenomenological research approach, this investigation explored the lived experiences of Louisiana teachers who piloted a 4-H STEM curriculum, focusing on the growth in agricultural literacy of the teachers while instructing third and eighth-grade students on the agricultural-based and STEM-focused topic of embryology. Employing a transcendental phenomenological approach, I acknowledged my biases through reflexivity and adhered to ethical considerations, including informed consent and confidentiality. Key findings emerged through four themes …

Death, Dreaming, And Diaspora: Achieving Orientation Through Afro-Spirituality, Liz Johnston, Jaime Elizabeth Johnston

LSU Doctoral Dissertations

Enslavement, colonization, and the systems that uphold racial injustice were and still are a series of new, unfathomable, and challenging experiences that prompt individuals within the diaspora to seek orientation. How does a human cope with centuries of attempts at the systematic destruction of their humanity, culture, and identity? How can they reclaim that identity, especially when so much of it seems lost? I address these questions by utilizing texts from the expansive body of work regarding ethnographic-historical-religious studies on Afro-spiritual practices to better analyze instances in literature in the ongoing practice of diasporic orientation. In this project, I argue …

Extracellular Carriers Control Lipid-Dependent Secretion, Delivery, And Activity Of Wnt Morphogens, Taciani De Almeida Magalhaes, Jingjing Liu, Charlene Chan, Kleiton Silva Borges, Jiuchun Zhang, Andrew J Kane, Bradley M Wierbowski, Yunhui Ge, Zhiwen Liu, Prabhath Mannam, Daniel Zeve, Ron Weiss, David T Breault, Pengxiang Huang, Adrian Salic

Faculty, Staff and Students Publications

WNT morphogens trigger signaling pathways fundamental for embryogenesis, regeneration, and cancer. WNTs are modified with palmitoleate, which is critical for binding Frizzled (FZD) receptors and activating signaling. However, it is unknown how WNTs are released and spread from cells, given their strong lipid-dependent membrane attachment. We demonstrate that secreted FZD-related proteins and WNT inhibitory factor 1 are WNT carriers, potently releasing lipidated WNTs and forming active soluble complexes. WNT release occurs by direct handoff from the membrane protein WNTLESS to the carriers. In turn, carriers donate WNTs to glypicans and FZDs involved in WNT reception and to the NOTUM hydrolase, …

Crispr-Dipoff: An Interpretable Deep Learning Approach For Crispr Cas-9 Off-Target Prediction, Md Toufikuzzaman, Md Abul Hassan Samee, M Sohel Rahman

Faculty, Staff and Students Publications

CRISPR Cas-9 is a groundbreaking genome-editing tool that harnesses bacterial defense systems to alter DNA sequences accurately. This innovative technology holds vast promise in multiple domains like biotechnology, agriculture and medicine. However, such power does not come without its own peril, and one such issue is the potential for unintended modifications (Off-Target), which highlights the need for accurate prediction and mitigation strategies. Though previous studies have demonstrated improvement in Off-Target prediction capability with the application of deep learning, they often struggle with the precision-recall trade-off, limiting their effectiveness and do not provide proper interpretation of the complex decision-making process of …

Pangenome Graphs Improve The Analysis Of Structural Variants In Rare Genetic Diseases., Cristian Groza, Carl F. Schreck, Warren A. Cheung, Emily G. Farrow, Isabelle Thiffault, Juniper Lake, William B. Rizzo, Gilad Evrony, Tom Curran, Guillaume Bourque, T Pastinen

Manuscripts, Articles, Book Chapters and Other Papers

Rare DNA alterations that cause heritable diseases are only partially resolvable by clinical next-generation sequencing due to the difficulty of detecting structural variation (SV) in all genomic contexts. Long-read, high fidelity genome sequencing (HiFi-GS) detects SVs with increased sensitivity and enables assembling personal and graph genomes. We leverage standard reference genomes, public assemblies (n = 94) and a large collection of HiFi-GS data from a rare disease program (Genomic Answers for Kids, GA4K, n = 574 assemblies) to build a graph genome representing a unified SV callset in GA4K, identify common variation and prioritize SVs that are more likely to …

Expanding Considerations For Treating Avoidant/Restrictive Food Intake Disorder At A Higher Level Of Care., Brianne N. Richson, Danielle C. Deville, Christina E. Wierenga, Walter H. Kaye, Ana L. Ramirez

Manuscripts, Articles, Book Chapters and Other Papers

Existing descriptions of the treatment of avoidant/restrictive food intake disorder (ARFID) at higher levels of care (HLOC) for eating disorders are limited, despite HLOC settings frequently serving patients with ARFID. The purpose of this commentary is to expand on the preliminary literature that describes pediatric ARFID treatment at HLOC by describing two specific components of our approach to treating pediatric ARFID that may not yet have traction in the current literature. Specifically, we highlight the utility of (1) treatment accommodations that appropriately account for patients' neurodevelopmental needs (e.g., executive functioning, sensory processing) and (2) the adjunctive use of Dialectical Behavior …

Catastrophe Of War, Sujit Kumar Singh, Ayushi Jaiswal

Critical Humanities

The paper selects the novel Palpasa Café (2005) by Nepali author Narayan Wagle to highlight the factors that contributed to the Maoist insurgency and counter-insurgency that punctured the Nepali consciousness. It will also critique Eurocentric trauma theory for diminishing the South Asian perspectives of trauma (incidents) from the main discourse of trauma theory. In addition, the paper will explore the detrimental impacts of war and conflict as experienced by Nepalese cops and civilians together, and its long-lasting imprint on their psyche as manifested in different forms of trauma in the text. The dissemination of the 'inarticulable trauma' concept into something …

An Affirmation Of Coexistence Between Artificial Intelligence (Ai) And Human Intelligence (Hi): An Inquiry Into The Structure Of Kazuo Ishiguro’S Novel, Klara And The Sun, Shiva Hari Mainaly

Critical Humanities

A narrative reflective of the perils and promises of automation entering the subjective realm of humankind, Kazuo Ishiguro’s latest novel, Klara and the Sun, confronts us with the notion of coexistence between artificial intelligence (AF) and human intelligence (HF) by uncovering a robust structure arising from the contestation amidst a host of binaries: Human versus machine, AI versus HI, self versus the other, science versus nature, and the list goes on. Although a vast majority of analytical inquiries into this novel uncover the incoherence of human identity and consciousness in the society deeply invested in affordances of the fifth industrial …

“This Wonderful Machine”: How Should We Teach Humanities Texts Like Gulliver’S Travels In The Time Of Chatgpt?, Richard J. Haslam

Critical Humanities

The quoted phrase in the essay title comes from a passage in Jonathan Swift's Gulliver’s Travels in which a Grand Academy of Lagado professor demonstrates a “wonderful Machine” that can generate scores of books “without the least Assistance from Genius or Study.” The essay explore the challenge for teaching classic humanities texts like Gulliver that the (perhaps not so) “wonderful Machine” called ChatGPT poses. Student Owen Terry’s Chronicle essay (May 12, 2023) identifies two crucial aspects of that challenge: “We don’t fully lean into AI and teach how to best use it, and we don’t fully prohibit it to keep …

From Polygraphs To Truth Machines: Artificial Intelligence In Lie Detection, Jo Ann Oravec

Critical Humanities

The proliferation of artificial intelligence (AI)-enhanced lie detection tools in business, educational, community, and governmental contexts signals a new era of deception detection. With these AI developments, collections of intimate biometric information such as facial and retinal data, keystroke patterns, brain scans, and physiological changes in the cardiovascular system are combined with personal profiles to produce analyses of a subject’s supposed veracity. This article explores some early lie detection technologies (such as the polygraph) and discusses the influences that lie detection initiatives have had in human interactions through the decades. It addresses the empirical issues of whether specific AI technologies …

Thriving In College: International, First-Generation, And Transfer Students, Hannah Webb, Nikita Kulkarni, Dustin Grabsch

SMU Journal of Undergraduate Research

Underrepresented-student groups experience unique challenges throughout their college experience, the impacts of which can be assessed by measuring students’ levels of thriving. The purpose of this study was to understand the thriving of underrepresented college students—first-generation, international, and transfer students, specifically. To understand this, we sought to measure students’ thriving levels and determine the experiences contributing to or detracting from their perception of thriving. This study utilized a sequential exploratory design using the established 72-item thriving quotient survey to measure students’ overall thriving levels. In addition, the study utilized a qualitative content analysis on an open-ended question asking participants to …