Digital Commons Network^™

To Whom It May Concern: A Story In Two Parts, Derek Detzler

The Prairie Light Review

No abstract provided.

Compliance And Systems Data Management Report: Monthly Waiver Participation Trends, May 2026, Tennessee. Department Of Disability And Aging

Compliance & System Data/Reports

This monthly report provides data on various aspects of the department's activities and programs.

Spleen Volume Reduction And Transfusion Independence With Momelotinib Versus Ruxolitinib And Associated Overall Survival With Momelotinib In Jak Inhibitor-Naive Patients With Myelofibrosis And Anemia: Subgroup Analyses Of Simplify-1, Francesca Palandri, Stephen T Oh, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Improvements in splenomegaly, anemia, and overall survival (OS) are key considerations in the management of patients with myelofibrosis. In the phase III SIMPLIFY-1 trial (NCT01969838), momelotinib was noninferior to ruxolitinib for spleen volume reduction ≥ 35% (SVR35) and nominally superior for transfusion independence (TI) at week 24 in Janus kinase (JAK) inhibitor-naive patients. However, the relative impact of these endpoints on OS in anemic patients has not been described.

MATERIALS AND METHODS: The present post hoc analysis evaluated week 24 SVR35, TI, and dual responses (SVR35 + TI) in patients with baseline hemoglobin < 10 g/dL.

RESULTS: SVR35 rates were similar overall …

Risk-Stratified Transitional Care And Cardiovascular Hospitalizations By Sex: A Secondary Analysis Of A Randomized Clinical Trial., Douglas S Lee, Chang Nancy Wang, Peter C Austin, Sharon E Straus, Michael E Farkouh, Alice Chong, Monica Taljaard, Stephanie Poon, Stuart Smith, Robert S Mckelvie, Robert M Iwanochko, Andrea Macdougall, Esam Elbarasi, Peter M Cram, Jiming Fang, Clare L Atzema, Jacob A Udell, Paula A Rochon, Michael J Schull, Susanna Mak, Heather J Ross

Heart and Vascular Articles

IMPORTANCE: Female patients with heart failure (HF) are older and more often present with preserved left ventricular ejection fraction (LVEF), whereas male patients present with more ischemic disease. Despite these differences, an emergency department-based acute HF strategy may be equally applicable to both sexes.

OBJECTIVE: To determine whether the strategy for acute HF management in the Comparison of Outcomes and Access to Care for Heart Failure (COACH) trial differed by sex.

DESIGN, SETTING, AND PARTICIPANTS: This prespecified secondary analysis of the multicenter COACH stepped-wedge, cluster-randomized clinical trial included 10 acute care hospitals in Ontario, Canada. Data were collected from January …

Agency Fact-Making, Haiyun Damon-Feng

Articles

Modern administrative-law scholarship, theory, and doctrine generally conceptualize agencies as engaging in three primary functions: rulemaking, enforcement, and adjudication. This understanding of agencies has informed deep debates surrounding the power, independence, and constitutional legitimacy of the administrative state. But the prevailing account is incomplete. It overlooks a fourth core function of the administrative state: its fact-making, or epistemic, function. Across the administrative state, agencies create and disseminate information in ways that are uniquely comprehensive and uniquely powerful. Agencies’ epistemic outputs include the census generated by the Census Bureau, repositories of public-health information maintained by the Centers for Disease Control and …

The Influence Of Social Media On The Product Life Cycle In Fast Fashion: A Shein Case Study On Environmental And Social Impacts, Clara R. Devine

Industrial Engineering Undergraduate Honors Theses

Fast fashion has transformed global consumer culture through its rapid product cycles, affordability, and accessibility. However, this model has also contributed significantly to environmental degradation, excessive textile waste, and unethical labor practices. Social media platforms have accelerated these patterns by amplifying short-lived trends and influencing consumer purchasing behavior. This study aims to analyze the relationship between social media activity and the fast-fashion life cycle, with a focus on how online engagement drives consumption, production speed, and environmental impact. The research utilized a quantitative and analytical approach, combining correlation analysis and time-series data to evaluate the connection between SHEIN’s growing user …

Elizabeth Gibson Drinko Honors Convocation, Honors College

Honors Convocation

The Elizabeth Gibson Drinko Honors Convocation Awards Program for Spring 2026, Marshall University, Huntington, West Virginia.

Midwives' Self-Efficacy In Perimenopause Care: An Educational Intervention, Yinka Sokunbi

Doctor of Midwifery Advances in Midwifery Projects

Study Purpose: This project evaluated the effectiveness of an asynchronous continuing education (CE) webinar in improving midwives’ self-efficacy to provide comprehensive perimenopause care.

Research Questions

1. What is the impact of a targeted CE webinar on midwives’ self-efficacy in providing comprehensive perimenopause care?

2. How do participants perceive the impact and acceptability of a pilot CE webinar?

Significance/Background: Despite midwifery’s defined role in lifespan care, engagement in perimenopause management remains limited. Gaps in formal education and continuing professional development contribute to low confidence in this area. Guided by Social Cognitive Theory, this project targeted self-efficacy as a modifiable factor influencing …

2026 May - Mary V. Jordan Center Newsletter, Mary V. Jordan Center, East Tennessee State University

Mary V. Jordan Center Newsletters

No abstract provided.

Upr Report Submissions: Compiled By The International Human Rights Clinic At The University Of Illinois Chicago School Of Law And The Human Rights At Home Litigation Clinic At The Saint Louis University School Of Law, Sarah Dàvila A., Lauren E. Bartlett

Faculty White Papers

This unofficial summary compiles information from reports submitted by civil society and others for the Fourth Cycle of the Universal Periodic Review of the United States.

The authors reviewed the submissions, which are reports from civil society and others, and grouped issues thematically, using the 2020 UPR themes and recommendations as the organizing framework. Within each theme, the authors synthesized recurring issues, patterns, and concerns identified across multiple submissions. For each issue, the unofficial summary follows a structured approach that presents international obligations first, followed by United States domestic law, and then facts drawn from the submissions. However, where reports …

Evaluation Of Flt3 Inhibition With Quizartinib During Busulfan Conditioning For Hematopoietic Stem Cell Transplantation, Catherine Jankovic

Biochemistry and Molecular Biology

Hematopoietic stem cell transplantation (HSCT) is one of the only curative therapy options for many hematologic malignancies. HSCT relies on effective conditioning regimens to deplete host hematopoietic cells and enable donor engraftment. The alkylating agent Busulfan is widely used in myeloablative conditioning strategies due to its potent cytotoxic effects on hematopoietic cells and ability to clear the bone marrow. However, optimization of conditioning strategies remains an important area of investigation to improve transplant outcomes and reduce toxicity. Preliminary studies have shown that the FLT3 inhibitor Quizartinib synergizes with some chemotherapeutic agents, suggesting that targeted inhibitors may enhance conventional conditioning regimens. …

The Constitutional Penumbras Of Home Rights, Gerald S. Dickinson

William & Mary Bill of Rights Journal

Justice William Douglas’s famous parable in Griswold v. Connecticut argued that the Bill of Rights contains penumbras—implied zones of privacy protections— that emanate from the First, Third, Fourth, and Fifth Amendments. His penumbral conception of privacy rights has sparked extensive debate among legal scholars, reflecting both its influence and its ongoing controversy. Yet, there is more to Justice Douglas’s penumbra story to explore. In expounding on his privacy innovations in Griswold, Justice Douglas explained that the Fourth and Fifth Amendments protect against all governmental invasions of the sanctity of a man’s home and the privacies of life. Indeed, the …

Locked And Unloaded: The Constitutional And Empirical Case For Firearm Safe Storage Advisories, Hillel Y. Levin, Kay L. Levine

William & Mary Bill of Rights Journal

Constitutional law haunts our efforts to reduce the number of firearm deaths each year. But even with the evolving scope of individual rights, sensible regulation remains possible.

This Article proposes one such regulatory tool. State governments legally can and pragmatically should require firearm sellers to advise their customers of the association between improper gun storage and the risk of accidental death and suicide. Mandatory safe storage advisories implicate two strands of constitutional jurisprudence: the First Amendment’s protection against compelled speech and the Second Amendment’s right to bear arms. While the Supreme Court has strengthened both doctrines in recent years, jurisdictions …

The Constitutional Future Of Trademark Tarnishment, Jake Linford

William & Mary Bill of Rights Journal

This Article is the first to examine whether trademark anti-tarnishment laws should be deemed constitutional after the Supreme Court’s 2024 decision in Vidal v. Elster. Anti-tarnishment laws protect famous brands from uses that could damage their reputation, even when consumers are not confused about who makes the tarnishing product.

The Supreme Court recently declared some trademark registration restrictions unconstitutional in Matal v. Tam and Iancu v. Brunetti. In these cases, the Court struck down federal laws that prevented registration of “disparaging” trademarks and “scandalous or immoral” trademarks because they categorized the registration bars as unconstitutional viewpoint-based restrictions. These …

The Delivery And Evaluation Of The Diabetes Prevention Program Through A Distance Education Modality, Celine Siddall

Student Projects for Graduate Degrees

Type 2 diabetes is a significant and growing public health concern, disproportionately affecting American Indian and Alaska Native populations. The Diabetes Prevention Program (DPP) has demonstrated effectiveness in reducing diabetes risk through lifestyle modification. However, implementation in rural and geographically isolated regions presents unique challenges. The COVID-19 pandemic further disrupted in-person delivery models, creating the need for rapid transformation to virtual formats.

This graduate project evaluated the implementation of a virtually delivered Prevent T2 at Chief Andrew Isaac Health Center program in the Tana Chiefs Conference region. This program was adapted for distance delivery using Zoom and supported by collaboration …

Human Subject Research Payments At The University Of Alaska Anchorage, Rebecca Kyle Van Wyck

Student Projects for Graduate Degrees

Human Subjects Research (HSR) participant payment processes are an underexamined but consequential component of research administration. At the University of Alaska, Anchorage (UAA), these processes op- erate within a complex institutional environment shaped by Institutional Review Board (IRB) requirements, Internal Revenue Service (IRS) reporting rules, and administrative procedures that remain only partially formalized. This capstone project examined how HSR participant payment processes are implemented in practice at UAA and where meaningful gaps exist between institutional policy and real-world execution.

The study used a qualitative single-institution case study design combining semi-structured interviews with five Principal Investigators (PIs), document analysis, and peer-institution …

Rising Prices, Rising Homes: How Inflation Shapes The U.S. Housing Market, Samantha Suarez

Theses & ETDs

This thesis explores the causes and consequences of inflation in the United States, with a particular focus on housing. It begins by examining the main drivers of housing inflation, including supply shortages, rising construction costs, low interest rates, and shifts in demand during and after the COVID-19 pandemic. These housing-specific factors are compared to broader sources of inflation such as fiscal stimulus, monetary policy, global supply chain disruptions, and geopolitical conflicts. The paper also analyzes how inflation affects households across different income groups. Because housing is a large share of total expenses, rising rents and home prices tend to place …

Biopsychosocial Mechanisms And Management Of Pain And Emotional Health In Fibrous Dysplasia/Mccune-Albright Syndrome, Camryn Berry

Doctoral Dissertations

Fibrous Dysplasia (FD) is a rare disease where healthy bone is replaced by lesions of fragile, porous tissue. FD lesions may affect a single bone or occur throughout the entire skeleton and can grow rapidly. A diagnosis of McCune-Albright syndrome (MAS) is made when FD is accompanied by endocrinopathies and skin hyperpigmentation. FD/MAS can cause debilitating complications, including disabilities, deformities, fractures, and chronic pain. Pain is one of the most common symptoms of FD/MAS and can have a profound impact on patients’ quality of life. However, FD/MAS pain is complex and varies substantially between patients. This complexity and a lack …

Navigating Departure: Understanding Factors Influencing Professionals Of Color In Student Affairs, Darnelle Bosquet-Fleurival

Doctoral Dissertations

Student Affairs Professionals of Color (SAPOCs) at predominantly white institutions (PWIs) navigate complex institutional environments shaped by racialized expectations, leadership structures, and systemic inequities. While existing research documents high turnover and burnout within student affairs, less is known about how mid-level to senior SAPOCs make meaning of their decisions to stay in or leave leadership roles over time. This qualitative study examines how institutional, interpersonal, and systemic dynamics shape professional sustainability and exit among SAPOCs in the Northeastern United States.Grounded in Critical Race Theory and Black Feminist Thought and informed by narrative inquiry methodology, this study draws on in-depth interviews …

Leveraging Dna Intercalation For The Development Of Tunable, Versatile Supramolecular Hydrogels, Shaina Marlene Hughes

Doctoral Dissertations

Supramolecular hydrogels have emerged as a versatile class of biomaterials capable of mimicking the dynamic behavior of natural tissues due to their inherent hydrophilicity, stimuli-responsiveness, and viscoelastic behavior. However, achieving both biocompatibility and mechanical tunability remains a challenge. This work utilizes DNA intercalation to create a programmable, sustainable hydrogel platform. By utilizing the reversible insertion of planar aromatic molecules between DNA base pairs, we demonstrate that the network’s dissociation kinetics and thermodynamic response are directly governed by the intercalator structure, offering a highly tunable strategy for stimuli-responsive biomaterials.To demonstrate the versatility of double stranded DNA (dsDNA) intercalating supramolecular hydrogels (DISHs), …

Linking Environmental Change, Microbial Community Assembly, And Function During A Novel Marine Phytoplankton Bloom Using Multi-Omics, Madison Renée Hurley

Doctoral Dissertations

Phytoplankton are central to marine ecosystem functioning, driving primary production, nutrient cycling, and higher trophic level dynamics. In the spring and summer of 2023, the Gulf of Maine experienced an unprecedented bloom of the dinoflagellate Tripos muelleri, reaching densities exceeding 50,000 cells L-1, an order of magnitude higher than previously recorded, and disrupting the region’s typical spring diatom-dominated succession. This bloom provided a unique opportunity to examine the metabolic strategies, ecological interactions, and environmental drivers underlying the bloom persistence and decline. An integrative approach was used, combining 18S and 16S rRNA amplicon sequencing, pigment and image analysis, network modeling, functional …

Neutral Giant: The United States And The Costa Rican Civil War Of 1948, James Irving

Doctoral Dissertations

This dissertation is a narrative microhistory of American diplomacy during Costa Rica’s transformative 1948 civil war. Emerging out of a contested presidential election, the war pitted the Costa Rican government of Teodoro Picado and its communist allies against an anticommunist, nationalist rebel movement led by José Figueres in a monthlong fight for political power. While existing histories of American policymaking have concluded almost unanimously that the United States intervened to support the rebels as part of its Cold War strategy in Latin America—labeling the civil war a precursor to the more infamous coup in Guatemala in 1954—this dissertation seeks to …

Assessment Of Correctness, Content Omission, And Risk Of Harm In Large Language Model Responses To Ophthalmology Continuing Medical Education Questions, Jacqueline L. Chen, Amanda J. Lu, Rohan Verma, Li Wang, Douglas D. Koch, Allison J. Chen

SKMC Student Presentations and Publications

PURPOSE: To evaluate the accuracy and prose responses of 2 large language models (LLMs) to ophthalmology continuing medical education questions.

DESIGN: Question prompts and multiple choice (MC) answer options were input into the 2 LLMs, and responses were analyzed for accuracy and assessed for evidence of correctness, completeness, bias, and potential harm using a previously reported standardized rubric.

SUBJECTS: Basic and Clinical Science Course questions and MC answer options from the American Academy of Ophthalmology question bank were used as inputs into the 2 LLMs (ChatGPT-4 and Google Vertex's Gemini Pro 1.5).

METHODS: The MC responses were assessed for accuracy …

Building The Foundation For Equitable Diabetes Education: Examining Trust And Digital Access In Rural And Unreserved Population, Niasia Hazelton Smalls

MUSC Theses and Dissertations

Disparities in patient portal use undermine equitable chronic disease management, particularly for adults with diabetes in rural and historically underserved communities. This explanatory sequential mixed-methods study examined the associations among trust in the healthcare system and patient portal use among U.S. adults, using nationally representative data from the Health Information National Trends Survey (HINTS) 2023 (N = 3,711), supplemented by semi-structured interviews with frontline healthcare providers. Bivariate analyses revealed that adults with diabetes reported lower trust (83% vs. 86%, p = 0.003) and lower portal use (62% vs. 66%, p = 0.014) compared to those without a diagnosis. Multivariate logistic …

Exploring Social Emotional Learning Competencies In Middle School Theatre Education, Katherine J. Mullins

Honors Theses

Social Emotional Learning (SEL) is a method of education in which students are taught to grow in multifaceted ways. Students learn and grow as more than just students in their respective subjects, they grow in emotional intelligence, empathy, and interpersonal skills as well. SEL is not always easy to incorporate into teaching practices, but it tends to lend itself well to a theatre education setting. In a middle school specific setting, SEL and theatre-based activities yield positive results in student competencies both in and out of the classroom. In this research, through comparative analysis and reflective inquiry, I aim to …

Equal Protection Under The Law: Constitutionality Of Current And Proposed Anti-Lgbtq+ Legislation In Tennessee And Its Potential Impact On Business, Henry J. Kalla

Honors Theses

In recent years, the Tennessee General Assembly has become a battleground of sorts for bills attempting to police the treatment of LGBTQ+ individuals. Multiple laws that impact LGBTQ+ citizens have sparked debate as interested parties on all sides seek to clarify the scope of equal protection, religious freedom, and free expression in this evolving age. Federal law has statutes in place that prohibit discrimination against individuals based on certain protected characteristics, but sexual orientation or transgender status are not explicitly among them. The states have interpreted this ambiguity as providing them the freedom to pass their own civil rights legislation …

Exploring The Impact Of Poverty On Financial Literacy: The Role Of Parental Education In College Student Financial Behavior, Zoe Williams

Honors Theses

Many college students experience financial stress, yet financial hardship is often explained as a simple lack of financial knowledge. Recent research suggests that how students are socialized around money may matter just as much as what they know. In this study, I examined whether parental education, specifically first-generation college status, changes the relationship between household income and financial health among undergraduate students at a regional public university in the southeastern United States. Participants included 204 undergraduates recruited through the university research pool. Students reported household income (categorized as < $50,000 or >$50,000), first-generation status, and financial behaviors. Financial literacy was measured using an …

The Culture Of The Convent: How Recruitment Shapes Success In Religious Life, Elizabeth A. Minneci

Honors Theses

Catholic nuns in the United States have experienced a substantial decline in membership, with an 80% decrease in new members from 1965 to 2023 (CARA, 2023). Sisters impact their communities in a multitude of ways, often through education or volunteerism efforts (CCUSA, 2026; Levin, 2011; Sisters of Mercy, 2025). Previous research on Catholic nuns has not qualitatively explored Catholic nuns’ recruitment efforts, with most research providing quantitative data insights (CARA). Thus, the purpose of this study is to identify the recruitment methods convents utilize to identify pain points and avenues for improvement. Seven religious sisters were recruited for this study. …

Toward An Understanding Of Social Marketing’S Influence On Alcohol-Related Behaviors In College Students: Health Promotion Strategies For College Campuses, Lily K. Richards

Honors Theses

Alcohol use among college students remains a persistent public health concern, influenced by a complex interaction of social, environmental, and behavioral factors. This literature review examines the prevalence of alcohol consumption in college populations, the associated short-term and long-term health consequences, and the role of social norms, peer influence, and environmental context in shaping drinking behaviors. Research consistently demonstrates that alcohol use is deeply embedded within college culture, where normative misperceptions and peer dynamics contribute to increased consumption. (Perkins, 2002; Borsari & Carey, 2001; Hingson et al., 2017). In addition, environmental factors such as alcohol availability and targeted marketing further …

The Effects Of The South Chattanooga Mentorship Program On Elementary School Children, Ana G. Morris

Honors Theses

This research study examines the impact of mentorship within the South Chattanooga Community Center’s after-school program, with a focus on elementary-aged students. The purpose of this study is to evaluate how one-on-one mentorship affects students’ academic development, behavior, and social-emotional learning. The program operates as a cost-free, five-day-a-week initiative designed to provide a safe and supportive environment for children who may lack consistent guidance outside of school. Using observational methods and direct interaction with students (quantitative and qualitative), this study examines mentorship influences key skills, including regulation, communication, relationship-building, and literacy abilities. It suggests that students who participate in the …