Digital Commons Network^™

Innovative Microwave-Assisted Biosynthesis Of Copper Oxide Nanoparticles Loaded With Platinum(Ii) Based Complex For Halting Colon Cancer: Cellular, Molecular, And Computational Investigations, Nada K. Sedky, Iten M. Fawzy, Afnan Hassan, Noha Khalil Mahdy, Samir N. Shamma, Reem T. Attia, Mohammad Y. Alfaifi, Serag Eldin Elbehairi, Fatma A. Mokhtar, Sherif Ashraf Fahmy

Faculty Journal Articles

In the current study, we biosynthesized copper oxide NPs (CuO NPs) utilizing the essential oils extracted from Boswellia carterii oleogum resin, which served as a bioreductant and capping agent with the help of microwave energy. Afterwards, the platinum(ii) based anticancer drug, carboplatin (Cr), was loaded onto the CuO NPs, exploiting the electrostatic interactions forming Cr@CuO NPs. The produced biogenic NPs were then characterized using zeta potential (ZP), high-resolution transmission electron microscopy (HRTEM), X-ray diffraction spectroscopy (XRD), and Fourier transform infrared spectroscopy (FTIR) techniques. In addition, the entrapment efficiency and release profile of the loaded Cr were evaluated. Thereafter, SRB assay …

Ua12/2/1 College Heights Herald, Wku Student Affairs

WKU Administration Documents

Magazine edition of the College Heights Herald for the period November 6, 2023 - January 29, 2024.

• Arnold, Emilee. WKU Memorabilia – Big Red, Hilltoppers
• Wilborn, Price. Renee Shaw Inducted into Hall of Distinguished Alumni
• Dobberstein, Molly. WKU’s Hall of Distinguished Alumni – Claude Bloch, Charles Reynolds, Amir Zaheri
• Costellow, Ali. LGBTQ+ WKU Alumni Share Stories from the Hill – Karen Stewart, Georgena Brackett, Spencer Jenkins, Seth Church
• Homecoming Hotspots – Restaurants
• Abney, Shayla. Veterans & ROTC Cadets Share Experiences on the Hill
• Edmonds, Luke & Jake McMahon. Home Field Advantage – Football Fans
• Dobberstein, Molly & Maggie Phelps. Who’s …

Representation Matters: Content Analysis Of Breastfeeding Images In A Commercial Stock Image Bank, Lauren M. Dinour, Melanie Shefchik

Department of Nutrition and Food Studies Scholarship and Creative Works

Several behavioral change theories posit that normative influences contribute to breastfeeding behaviors and disparities. Given that media has historically presented a narrow view of what is deemed normative in human milk feeding, this study describes who and what is represented in breastfeeding images available in a stock image bank, and whether differences exist based on the breastfeeding parent’s skin color. Using content analysis, the most relevant 2% (n = 2284) of breastfeeding and lactation images in Adobe Stock were coded for 60 variables within 12 categories, such as skin color, ability, setting, skin exposure, etc. Descriptive statistics were used …

Investigating The Impacts Of Shame-Proneness On Students’ State Shame, Self-Regulation, And Learning, Jeremiah Sullins, Jeannine Turner, Juhee Kim, Steven Barber

Faculty Research and Publications

We explored relationships between students’ shame-proneness and their experiences of state shame, self-regulation, and learning in a laboratory. We conducted two studies with different content: physics (Study 1, n = 179) and the circulatory system (Study 2, n = 85). We first evaluated students’ shame-proneness, self-regulation, and content knowledge (pretest). Then, half of the students participated in the experimental condition where state shame was induced. Subsequently, we evaluated students’ state shame and learning gains. In both studies, t-tests demonstrated that the experimental manipulation effectively induced higher levels of state shame. Follow-up 2 (experimental/control condition) by 2 (high/low shame-proneness) ANOVAs revealed …

The Utah Statesman, January 29, 2024, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Copyright And Covid, Sean Flynn

Joint PIJIP/TLS Research Paper Series

During the COVID-19 pandemic it became widely recognized that speedier access to patent rights should be enabled to speed global scale-up of vaccine production. This understanding was expressed in a proposal by India and South Africa that the World Trade Organization suspend multilateral intellectual property rules on COVID vaccines, treatment and containment. The original waiver proposal proposed a suspension of WTO rules on all forms of intellectual property needed for a broad range of COVID-19 response measures, including “vaccination,” “treatment,” and “containment.” The final “TRIPS Waiver,” however, was ultimately limited to a minor provision of TRIPS permitting greater use of …

Patient Care Assistants Making Meaning Of Their Work In Nursing Homes, Justina Mae Elizabeth Knowles

Walden Dissertations and Doctoral Studies

No abstract provided.

The Rider (2024-01-29), Natalie Lapsley

The Rider Archives

Vol.9 No.17

Effective Strategies Leaders Use To Enhance The Retention Of Frontline Workers In The Fast-Food Industry, Kimberly Jean Nzuwah

Walden Dissertations and Doctoral Studies

No abstract provided.

Hygrothermal Risk Assessment Of External Wall Insulation Retrofit To Non-Traditional Wall Types In An Irish Context, Using The Glaser Method And A Heat, Air And Moisture Transient Model, Gareth Mcdonnell, Joseph Little

Articles

The Climate Action Plan 2019 targets the low-energy retrofit of 500,000 existing Irish homes before 2030.1 Up to 80 per cent of building failures can be attributed to moisture risks.2 The literature indicated that external wall insulation (EWI, ETICS) failures are mostly due to moisture ingress at junctions and interfaces. A hygrothermal risk assessment of EWI on three walls with rendered concrete/concrete blockwork/cavity walls in Dublin, Belfast and Belmullet was undertaken using transient numerical simulation and the Glaser method. The guidance, common practice indicates a preference for Glaser. The initial simulation results were compared to assess the appropriateness of Glaser. …

Week Of January 29, 2024, Student Life

College, School and Department Newsletters, Magazines, and Journals

Your weekly hub for events, resources and updates.

Patient-Derived Models Of Cancer In The Nci Pdmc Consortium: Selection, Pitfalls, And Practical Recommendations., Amber N Habowski, Deepthi P Budagavi, Sandra D Scherer, Arin B Aurora, Giuseppina Caligiuri, William F Flynn, Ellen M Langer, Jonathan R Brody, Rosalie C Sears, Giorgia Foggetti, Anna Arnal Estape, Don X Nguyen, Katerina A Politi, Xiling Shen, David S Hsu, Donna M Peehl, John Kurhanewicz, Renuka Sriram, Milagros Suarez, Sophie Xiao, Yuchen Du, Xiao-Nan Li, Nora M Navone, Estefania Labanca, Christopher D Willey

Faculty Research 2024

For over a century, early researchers sought to study biological organisms in a laboratory setting, leading to the generation of both in vitro and in vivo model systems. Patient-derived models of cancer (PDMCs) have more recently come to the forefront of preclinical cancer models and are even finding their way into clinical practice as part of functional precision medicine programs. The PDMC Consortium, supported by the Division of Cancer Biology in the National Cancer Institute of the National Institutes of Health, seeks to understand the biological principles that govern the various PDMC behaviors, particularly in response to perturbagens, such as …

Utility Of Long-Read Sequencing For All Of Us., M Mahmoud, Y Huang, K Garimella, Peter A Audano, W Wan, N Prasad, R E Handsaker, S Hall, A Pionzio, M C Schatz, M E Talkowski, E E Eichler, S E Levy, F J Sedlazeck

Faculty Research 2024

The All of Us (AoU) initiative aims to sequence the genomes of over one million Americans from diverse ethnic backgrounds to improve personalized medical care. In a recent technical pilot, we compare the performance of traditional short-read sequencing with long-read sequencing in a small cohort of samples from the HapMap project and two AoU control samples representing eight datasets. Our analysis reveals substantial differences in the ability of these technologies to accurately sequence complex medically relevant genes, particularly in terms of gene coverage and pathogenic variant identification. We also consider the advantages and challenges of using low coverage sequencing to …

Turkey Vs Italy: Gender And Cyber Security, Esra Merve Caliskan, Irem Itegin

Journal of Cybersecurity Education, Research and Practice

With the development of technology, security, a core human concern throughout history,has changed and branched out into new areas. Novel security concepts, including environmental security, economic security, and cybersecurity, have emerged as a result of these expanding areas. The importance of cybersecurity has increased in the linked world of today as a result of how prevalent technology is in our daily lives. This study looks at how the literature on international relations approaches the idea of cybersecurity, with an emphasis on the role gender dynamics play.

This study adopts a comprehensive strategy in recognition of the possibility that people of …

Buah Buton In Traditional House Interior: Representation Of Women's Role And Influence, Fakhrur Razi Maamor, Sabzali Musa Kahn, Basitah Taif

Interiority

Buah buton is a three-dimensional wooden carving as an interior object in the traditional house of Negeri Sembilan. The purpose of this article is to establish a link between the buah buton in Luak Tanah Mengandung, Negeri Sembilan and the position of women who connect the legacy and leadership in the Adat Perpatih, a customary community law, and how such a relationship manifests itself within the traditional house's interior. The function of buah buton was revealed through fieldwork and interviews with community leaders, which were then combined into a narrative that represented the function of buah buton. The …

Typology And Interiority Of Cohousing In Europe 1981–2021, Virginia De Jorge-Huertas, Justo De Jorge-Moreno

Interiority

This work aims to research the connection between cohousing architecture and interiority. For this purpose, the analyses are structured in two phases. The first consists of the characterisation and identification of underlying typologies of European cohousing projects in the last three decades, 1981–2022. The second phase consists of the connection between the interiority concepts (in terms of planimetry, typology, spatial syntax, and interior spaces) and the cohousing architecture in the case studies selected from the first phase, which made it possible to compare cohousing projects and propose future strategies. The research identifies a typology with two clusters of cohousing projects …

Cultural Humility Training With A Simulated Therapy Client: A Qualitative Case Study, Justine Piontek

Electronic Theses and Dissertations Archive

A qualitative case study explored seven counseling psychology doctoral trainees’ experiences in a small-group training with a simulated therapy client of a marginalized identity, and more specifically, the trainees’ perceptions of how the interaction with the simulated client influenced their cultural humility development. The simulation training was designed to mirror a therapy intake and the case profile reflected an African American client presenting with race-based stress from ongoing discrimination across several life domains. A thematic analysis was performed on the training de-brief focus group yielding five themes: (1) trainees’ impressions (2) trainees’ affective responses (3) comparisons to clinical work with …

Effects Of Alcohol Consumption On Gambling Warning Message Recall And Recognition, Tori Horn

Electronic Theses and Dissertations Archive

Warning messages inform consumers of potential risks associated with product use and reduce the likelihood of excessive engagement in risky behaviors. Evidence supports that such messages can educate consumers and reduce gambling. Questions remain about how acute alcohol consumption may interfere with message reception and retention. Memory literature suggests that while alcohol consumption may not influence general message reception it may impact the recall of specific details of the messages. To examine this effect, participants (n = 82) were randomly assigned to consume alcoholic beverages (target blood alcohol concentrations of 0.06-0.08%) or juice. Participants then gambled on slot machines in …

The Effects Of Resilience And Optimism In Maternal Role Attainment After Six To Twelve Months Postpartum In Women Hospitalized For Pregnancy Complications, Marianne Allen

Dissertations

Each year in the US, approximately 1,200,000 pregnant women are hospitalized on bed rest with the intent to improve pregnancy outcomes. However, antepartum bed rest is not benign and may contribute to physical debilitation, postpartum depression (PPD), impaired maternal role attainment (MRA), and altered maternal-infant attachment. There are gaps in the literature about the effects of resilience, optimism, and PPD on MRA and the effects of resilience and optimism on PPD at six to 12 months postpartum. Although the effects of resilience and optimism have been studied in general adult populations, few studies have considered resilience and optimism as protectors …

Dorsal Hippocampus To Nucleus Accumbens Projections Drive Reinforcement Via Activation Of Accumbal Dynorphin Neurons, Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J Widman, Robert J Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Robert W Gereau 4th, Jose A Morón, Et Al.

2020-Current year OA Pubs

The hippocampus is pivotal in integrating emotional processing, learning, memory, and reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for episodic, spatial, and associative memory, and has been shown to be necessary for context- and cue-associated reward behaviors. The nucleus accumbens (NAc), a central structure in the mesolimbic reward pathway, integrates the salience of aversive and rewarding stimuli. Despite extensive research on dHPC→NAc direct projections, their sufficiency in driving reinforcement and reward-related behavior remains to be determined. Our study establishes that activating excitatory neurons in the dHPC is sufficient to induce reinforcing behaviors through its direct projections to the …

Miniaturized Fluorescence Ph Sensor With Assembly Free Ball Lens On A Tapered Multimode Optical Fiber, Bohong Zhang, Farhan Mumtaz, Muhammad Roman, Dinesh Reddy Alla, Rex E. Gerald, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

In biochemistry, the absence of a compact, assembly-free pH sensor with high sensitivity and signal-to-noise ratio has been a persistent hurdle in achieving accurate pH measurements in real time, particularly in complex liquid environments. This manuscript introduces what we believe to be a novel solution in the form of a miniaturized pH sensor utilizing an assembly-free ball lens on a tapered multimode optical fiber (TMMF), offering the potential to revolutionize pH sensing in biochemical applications. A multimode optical fiber (MMF) was subjected to tapering processes, leading to the creation of an ultra-thin needle-like structure with a cross-sectional diameter of about …

Adult Neuromuscular Choristoma, A Rare Peripheral Nerve Pathology: Illustrative Case, Ashley Ricciardelli, Alex Flores, Hsiang-Chih Lu, Ekin Guney, Arie Perry, Joey Grochmal

Faculty, Staff and Students Publications

Background: Neuromuscular choristomas (NMCs) are rare tumors involving aberrant intercalation of muscle fibers into peripheral nerves, most commonly the sciatic nerve. Although benign, these lesions risk developing into NMCs with desmoid-type fibrosis (NMC-DTFs), aggressive lesions potentially requiring amputation. Currently, information on NMCs and the link between NMCs and NMC-DTFs is limited in adults, with the majority of cases reported in children. We present the case of a 66-year-old male with a sciatic NMC alongside a Preferred Reporting Items for Systematic Reviews and Meta-Analyses-based systematic review of similar cases to better characterize this lesion in the adult population.

Observations: A male …

Invasive Group A Streptococcus In Infants Less Than 1-Year Of Age From 2012 To 2022: A Single-Center Experience, Taylor Nack, Jesus G Vallejo, James Dunn, Anthony R Flores, J Chase Mcneil

Faculty, Staff and Students Publications

The incidence of invasive Group A Streptococcus (iGAS) has varied throughout the COVID-19 pandemic. We reviewed iGAS infections in infants ≤1 year from 2012 to 2022. Twenty-five percent of cases occurred in the last quarter of 2022. Pneumonia (21.8%) was the most common presentation. Twenty-one patients (65.6%) were successfully transitioned to oral antibiotics.

P*Law 2024, Center For Public Service Law

2023–2024 Flyers

This document outlines the full schedule for P*LAW Week 2024 at Cardozo School of Law, hosted by the Center for Public Service Law. Held from January 29 to February 1, the week featured panels, workshops, and student-led presentations on critical public interest topics, including immigration, incarceration, housing justice, student debt, reproductive rights, and exoneration. With contributions from legal professionals, alumni, faculty, and students, the events provided education, mentorship, and career development opportunities for those pursuing paths in public interest law.

Radiofrequency Ablation Of Thyroid Nodules: A Clinical Review Of Treatment Complications, Peter P. Issa, Katherine Cironi, Leely Rezvani, Emad Kandil

School of Medicine Faculty Publications

Radiofrequency ablation (RFA) is a minimally invasive ablative modality for the treatment of thyroid nodules. Reports of RFA use have demonstrated an impressive safety profile and excellent volume reduction rates between 60-90%. Given its increased popularity in the United States as well as globally, numerous recent works have been published and a discussant of relevant complications incorporating recent insight may assist practitioners in minimizing complications and optimizing patient outcomes. Herein, we provide a comprehensive and updated review of the reported complications and side effects following RFA, summarizing their frequency and clinical presentation. We also describe a means of minimizing such …

Landslide Susceptibility Assessment Of The Asi Watershed, Southern Türkiye, Senem Teki̇n, Adolfo Quesada Román, Tolga Çan

Turkish Journal of Earth Sciences

Landslides constitute recurrent natural hazards worldwide with greater socioeconomic impacts in low-income places. Landslide susceptibility studies are carried out to determine the potential for landslides to occur in a region, to predict possible risks in the future and to integrate this information into sustainable planning and management strategies. Slip-type landslides occur in limited areas of less than 1% of the Asi watershed in Southern Türkiye. Therefore, meaningful estimations cannot be made with classical statistical models. So, using the maximum entropy approach (MaxEnt), a technique for estimating based on a small number of observations, a landslide susceptibility assessment was constructed. The …

The Role Of The Cdk8 Kinase Module In Maintaining Proteostasis, Stephen Willis

Theses and Dissertations

The underlying etiology of numerous disease states results from perturbations in the maintenance of cellular proteostasis. Carcinogenesis relies on these perturbations to foster uncontrolled cell growth and eventual metastases, while neurodegenerative diseases are a consequence of such perturbations. Control of these processes occurs at numerous molecular levels, commonly starting with transcription. A key transcriptional complex that is involved is the CDK8 Kinase Module (CKM). The CKM is conserved from yeast to man, forming a tetrameric complex consisting of MED12, MED13, CDK8, and CCNC. The CKM has not only been implicated in a variety of cancers but also in a spectrum …

Mosaic Loss Of Y Chromosome Is Associated With Aging And Epithelial Injury In Chronic Kidney Disease, Parker C Wilson, Amit Verma, Yasuhiro Yoshimura, Yoshiharu Muto, Haikuo Li, Nicole P Malvin, Eryn E Dixon, Benjamin D Humphreys

2020-Current year OA Pubs

BACKGROUND: Mosaic loss of Y chromosome (LOY) is the most common chromosomal alteration in aging men. Here, we use single-cell RNA and ATAC sequencing to show that LOY is present in the kidney and increases with age and chronic kidney disease.

RESULTS: The likelihood of a cell having LOY varies depending on its location in the nephron. Cortical epithelial cell types have a greater proportion of LOY than medullary or glomerular cell types, which may reflect their proliferative history. Proximal tubule cells are the most abundant cell type in the cortex and are susceptible to hypoxic injury. A subset of …

Luz Solis Interview, Mark Naison

Oral Histories

Interviewees: Ms. Luz Soliz-Ramos , Gil

Chapter of Alpha Kappa Alpha Sorority, Incorporated ©

Interviewers: Dr. Mark Naison, Dr. Lisa Betty, Lucy Blanco

Date: December 10, 2023

Summarized by Amy Rini January 28, 2024

Ms. Luz Soliz-Ramos from Honduras, is a Garifuna dancer, choreographer, teacher, and activist. Soliz-Ramos is the founder of the Bronx based Garifuna Heritage Center for the Arts and Culture and Co-Choreographer & Artistic Director of the Wabafu Garifuna Dance Theatre, which was established as the Hamalali Wayunagu Garifuna Dance Company in 1992.

Immigration from Honduras wasn’t easy for those who only spoke Garifuna and not Spanish, …

Maria Aponte Interview, Mark Naison

Oral Histories

Disciplines

African American Studies

Abstract

Summary by Jocelyn Defex.

This interview for the Bronx African American History Project was with Maria Aponte, a Non-profit organization founder, educator, author, poet, performance artist, and community arts activist. A Fordham University alum, Carlos Rico, interviewed her for the Bronx COVID-19 Oral History Project.

Aponte discusses her childhood; she grew up in “El Barrio” (Washington Heights, NY) and moved to the Bronx in the late 70s. Before becoming an activist, she was a theater actress, and she felt that her role helped to break down Latino, women, and person-of-color stereotypes in the theater. At …