Digital Commons Network^™

Formulation And Aerosol Jet Printing Of Nickel Nanoparticle Ink For High-Temperature Microelectronic Applications And Patterned Graphene Growth, Nicholas Mckibben, Michael Curtis, Olivia Maryon, Mone’T Sawyer, Maryna Lazouskaya, Josh Eixenberger, Zhangxian Deng, David Estrada

Materials Science and Engineering Faculty Publications and Presentations

Aerosol jet printing (AJP) is an advanced manufacturing technique for directly writing nanoparticle inks onto target substrates. It is an emerging reliable, efficient, and environmentally friendly fabrication route for thin film electronics and advanced semiconductor packaging. This fabrication technique is highly regarded for its rapid prototyping, the flexibility of design, and fine feature resolution. Nickel is an attractive high-temperature packaging material due to its electrical conductivity, magnetism, and corrosion resistance. In this work, we synthesized nickel nanoparticles and formulated an AJP ink, which was printed on various material surfaces. Thermal sintering experiments were performed on the samples to explore the …

Ethnic Identity As A Mediator Of Mental Health In New Mexico's Genizaro Population At The Pueblo Of Abiquiu, New Mexico, 1930-2017: A Critical Ethnography, Annabelle X. Gutierrez Sisneros

Dissertations

The usefulness of the qualitative research paradigm of Critical Ethnography in health disparities research is viewed in this doctoral study as being of paramount importance within the praxis of nursing, specifically, in providing a window into the scene of mental health within the field of advanced psychiatric nursing, amongst the Genizaro people at the Pueblo of Abiquiu in New Mexico, a border area. The life patterns heard through 24 semi-structured interviews conducted from 2015-2017, included a portrayal of a narrative that heartens the continuance of the transmission of history, language, tradition, healing, and philosophies of this Indigenous Nation, which are …

The Prospector, February 27, 2024, Utep Student Publications

The Prospector

No abstract provided.

Association Of Plasma Ykl-40 With Mri, Csf, And Cognitive Markers Of Brain Health And Dementia, Matthew P Pase, Jayandra J Himali, Raquel Puerta, Alexa S Beiser, Mitzi M Gonzales, Claudia L Satizabal, Qiong Yang, Hugo J Aparicio, Daniel J Kojis, Charles S Decarli, Oscar L Lopez, Will Longstreth, Vilmundur Gudnason, Thomas H Mosley, Joshua C Bis, Alison Fohner, Bruce M Psaty, Mercè Boada, Pablo García-González, Sergi Valero, Marta Marquié, Russell Tracy, Lenore J Launer, Agustín Ruiz, Myriam Fornage, Sudha Seshadri

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVES: Higher YKL-40 levels in the CSF are a known biomarker of brain inflammation. We explored the utility of plasma YKL-40 as a biomarker for accelerated brain aging and dementia risk.

METHODS: We performed cross-sectional and prospective analyses of 4 community-based cohorts in the United States or Europe: the Age, Gene/Environment Susceptibility-Reykjavik Study, Atherosclerosis Risk in the Communities study, Coronary Artery Risk Development in Young Adults study, and Framingham Heart Study (FHS). YKL-40 was measured from stored plasma by a single laboratory using Mesoscale Discovery with levels log transformed and standardized within each cohort. Outcomes included MRI total …

A Qualitative Examination Of Teachers’ Experiences Building Student Resilience In Rural Kenya, Priscilla Ann Stafford Allen

Walden Dissertations and Doctoral Studies

Students in rural and underresourced school settings often perform poorly due to adversity. This is evident in subcounty schools where challenges such as domestic violence and low socioeconomic status further impact students' academic performance. Researchers have demonstrated that the relationship between students and teachers is instrumental in building resilience and developing social emotional competence. By fostering resilience, teachers can play a crucial role in mitigating these challenges. However, few studies have examined teacher experience in building resilience in students through a qualitative study. Using a generic qualitative descriptive study and grounded in the theory of resilience, semistructured interviews were completed …

Re: Comments On: Berkeley Pit And Discharge Pilot Project, Quarterly Pilot Project Report, Third Quarter 2023, Dated December 20, 2023, Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Extrasynaptic Localization Is Essential For Α5gabaa Receptor Modulation Of Dopamine System Function, Alexandra M. Mccoy, Thomas D. Prevot, Md Yeunus Mian, Dishary Sharmin, Adeeba N. Ahmad, James M. Cook, Etienne L. Sibille, Daniel J. Lodge

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Dopamine system dysfunction, observed in animal models with psychosis-like symptomatology, can be restored by targeting gamma-aminobutyric acid type A receptors (GABAARs) containing the α5, but not α1, subunit in the ventral hippocampus (vHipp). The reason for this discrepancy in efficacy remains elusive; however, one key difference is that gamma-aminobutyric acid type A receptors containing the α1 subunit (α1GABAARs) are primarily located in the synapse, whereas gamma-aminobutyric acid type A receptors containing the α5 subunit (α5GABAARs) are mostly extrasynaptic. To test whether receptor location is responsible for this difference in efficacy, we injected an siRNA into the vHipp to knock down …

Rbpms Regulates Cardiomyocyte Contraction And Cardiac Function Through Rna Alternative Splicing, Peiheng Gan, Zhaoning Wang, Svetlana Bezprozvannaya, John R Mcanally, Wei Tan, Hui Li, Rhonda Bassel-Duby, Ning Liu, Eric N Olson

Faculty, Staff and Student Publications

Aims: RNA binding proteins play essential roles in mediating RNA splicing and are key post-transcriptional regulators in the heart. Our recent study demonstrated that RBPMS (RNA binding protein with multiple splicing) is crucial for cardiac development through modulating mRNA splicing, but little is known about its functions in the adult heart. In this study, we aim to characterize the post-natal cardiac function of Rbpms and its mechanism of action.

Methods and results: We generated a cardiac-specific knockout mouse line and found that cardiac-specific loss of Rbpms caused severe cardiomyocyte contractile defects, leading to dilated cardiomyopathy and early lethality in adult …

Examining Technology Use And Competence Of Higher Education Academics During The Covid-19 Pandemic, Devrim Akgunduz, Aysegul Kinik Topalsan

Higher Learning Research Communications

Objectives: The present study describes the utilization frequency and competencies of educational technologies among academics at a university in Turkey during the COVID-19 pandemic.

Methods: Participants were 391 faculty members and lecturers working in the faculties and vocational schools of a Turkish university during the 2020–2021 academic year. A survey included questions regarding the use of educational technologies and perceived competency in the use of those technologies.

Results: Academics are more familiar with distance education than hybrid or blended learning. Academics reported that blended learning, hybrid learning, and distance education provide more effective education on integrating technology but report that …

Bridging Therapy With Axicabtagene Ciloleucel For Large B-Cell Lymphoma: Results From The Us Lymphoma Car-T Consortium, Michael D Jain, Miriam T Jacobs, Feng Gao, Loretta J Nastoupil, Jay Y Spiegel, Yi Lin, Saurabh Dahiya, Matthew Lunning, Lazaros Lekakis, Patrick Reagan, Olalekan Oluwole, Joseph Mcguirk, Abhinav Deol, Alison R Sehgal, Andre Goy, Brian T Hill, Charalambos Andreadis, Javier Munoz, Julio C Chavez, N Nora Bennani, Aaron P Rapoport, Julie M Vose, David Miklos, Sattva S Neelapu, Frederick L Locke, Armin Ghobadi

Faculty, Staff and Student Publications

During the manufacturing period of autologous chimeric antigen receptor (CAR) T-cell therapy, patients may experience a decline in their condition due to cancer progression. In this study, we investigated the impact of bridging therapy (BT) on the outcome of patients with relapsed/refractory large B-cell lymphoma who received antilymphoma treatment between leukapheresis and axicabtagene ciloleucel (axi-cel) infusion. We conducted our analysis using data from the multicenter US Lymphoma CAR-T Consortium, with a median follow-up of 33 months (range, 4.3-42.1). Out of the 298 patients who underwent leukapheresis, 275 patients received axi-cel. A total 52% of patients (n = 143) who received …

Differential Upregulation Of Th1/Th17-Associated Proteins And Pd-L1 In Granulomatous Mycosis Fungoides, Mario L Marques-Piubelli, Jesus Navarrete, Debora A Ledesma, Courtney W Hudgens, Rossana N Lazcano, Ali Alani, Auris Huen, Madeleine Duvic, Priyadharsini Nagarajan, Phyu P Aung, Ignacio I Wistuba, Jonathan L Curry, Roberto N Miranda, Carlos A Torres-Cabala

Faculty, Staff and Student Publications

Granulomatous Mycosis Fungoides (GMF) is a rare form of mycosis fungoides (MF) characterized by a granulomatous infiltrate associated with the neoplastic lymphoid population and is considered to have a worse prognosis compared with regular MF. The upregulation of the T helper (Th) axis, especially Th17, plays an important role in the pathogenesis of several inflammatory/infectious granulomatous cutaneous diseases, but its role in GMF is still not elucidated to date. In this study, we evaluated the immunohistochemical expression of Th1 (Tbet), Th2 (GATA-3), Th17 (RORγT), T regulatory (Foxp3), and immune checkpoint (IC) (PD-1 and PD-L1) markers in a cohort of patients …

A Phase 1/2 Study Of Mini-Hyper-Cvd Plus Venetoclax In Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia, Nicholas J Short, Elias Jabbour, Nitin Jain, Jayastu Senapati, Lewis Nasr, Fadi G Haddad, Zhenhua Li, Yu-Chih Hsiao, Jun J Yang, Naveen Pemmaraju, Maro Ohanian, William G Wierda, Guillermo Montalban-Bravo, Gautam Borthakur, Lina Han, Lianchun Xiao, Xuelin Huang, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian

Faculty, Staff and Student Publications

Preclinical studies suggest that Bcl-2 inhibition with venetoclax has antileukemic activity in acute lymphoblastic leukemia (ALL) and may synergize with conventional chemotherapy. We designed a phase 1/2 clinical trial to evaluate the safety and efficacy of low-intensity chemotherapy in combination with venetoclax in adults with relapsed or refractory ALL. Patients received the mini-hyper-CVD regimen (dose-attenuated hyperfractionated cyclophosphamide, vincristine, and dexamethasone alternating with methotrexate and cytarabine) in combination with venetoclax (200 mg or 400 mg daily) on days 1 to 14 in cycle 1 and on days 1 to 7 in consolidation cycles. Twenty-two patients were treated. The median number of …

Mortality After Major Cardiovascular Events In Survivors Of Childhood Cancer, Wendy Bottinor, Cindy Im, David R Doody, Saro H Armenian, Alexander Arynchyn, Borah Hong, Rebecca M Howell, David R Jacobs, Kirsten K Ness, Kevin C Oeffinger, Alexander P Reiner, Gregory T Armstrong, Yutaka Yasui, Eric J Chow

Faculty, Staff and Student Publications

Background: Adult survivors of childhood cancer are at risk for cardiovascular events.

Objectives: In this study, we sought to determine the risk for mortality after a major cardiovascular event among childhood cancer survivors compared with noncancer populations.

Methods: All-cause and cardiovascular cause-specific mortality risks after heart failure (HF), coronary artery disease (CAD), or stroke were compared among survivors and siblings in the Childhood Cancer Survivor Study (CCSS) and participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study. Cox proportional hazard regression models were used to estimate HRs and 95% CIs between groups, adjusted for demographic and clinical …

At Chdi Conference, Advocates Inspire Acceleration Of Quest For Huntington’S Disease Therapies, Kenneth P. Serbin Phd

At Risk for Huntington's Disease

No abstract provided.

Dental Board Of California, Emily Powers, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Medical Board Of California, Emily Powers, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Board Of Pharmacy, Alexandra Harten, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Board Of Registered Nursing, Emily Powers, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Veterinary Medical Board, Alexandra Harten, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Bureau Of Private Postsecondary Education, Katie Gonzalez

California Regulatory Law Reporter

No abstract provided.

Department Of Insurance, Alexandra Harten, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Public Utilities Commission, Erol Kilic, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Key

California Regulatory Law Reporter

No abstract provided.

Comparative Efficacy, Quality Of Life, Safety, And Tolerability Of Atogepant And Rimegepant In Migraine Prevention: A Matching-Adjusted Indirect Comparison Analysis, Cristina Tassorelli, Kateryna Onishchenko, Rashmi B. Halker Singh, Molly Duan, Laure Dupont-Benjamin, Matthew Hemstock, Corey Voller, Peter Mcallister, Stephanie J. Nahas, Pranav Gandhi, Jessica Ailani

Department of Neurology Faculty Papers

BACKGROUND: Comparative evaluations of preventive migraine treatments can help inform clinical decision making for managing migraine in clinical practice.

METHODS: An anchored matching-adjusted indirect comparison analysis was conducted using pooled participant-level data from two phase 3 atogepant trials (ADVANCE and PROGRESS) and one phase 2/3 rimegepant trial (BHV3000-305) to evaluate the relative efficacy and safety/tolerability of atogepant and rimegepant as preventive migraine treatments. Participants receiving atogepant 60 mg once daily, rimegepant orally disintegrating tablet 75 mg once every other day, and placebo were included. Only participants meeting the BHV3000-305 inclusion/exclusion criteria were analyzed: ≥6 monthly migraine days and ≤18 monthly …

School Counseling Site Supervisors’ Lived Experience Of Supervision Preparedness, Erin Augustine

Walden Dissertations and Doctoral Studies

U.S. counseling programs accredited by the Council for Accreditation of Counseling and Related Educational Programs mandate specific supervision requirements for counselors-in-training, in all specialty areas. Supervising school counselors-in-training (SCITs) differs due to the unique responsibilities of school counselors, which encompass crisis response, curriculum development, consultation, data management, small group and individual counseling, leadership, and student advocacy. The purpose of this hermeneutic phenomenological study was to explore the lived experiences of preparedness levels of school counselor site supervisors. Data collection involved semistructured interviews with six participants who had all served or were currently serving as a school counseling site supervisor. The …

The Effects Blood Flow Restriction Therapy Augmented With Low-Intensity Exercise On Improving Chronic Pain And Functional Status In Individuals With Rheumatoid Arthritis And Osteoarthritis, Marketa Jones

Doctorate in Kinesiology

Individuals suffering from rheumatoid arthritis (RA) and osteoarthritis (OA) commonly experience chronic pain and functional limitations, which are often accompanied by comorbidities, including depression, fatigue, obesity, and heart disease. While exercise has been identified as an effective, low-cost treatment for these conditions, chronic pain, and limited functionality can pose significant obstacles for those diagnosed with these conditions. Recent research has investigated the potential of blood flow restriction therapy (BFRT) in rehabilitating musculoskeletal injuries and enhancing skeletal muscle properties. The objective of this 6-week study is to examine the potential impact BFRT combined with low-intensity exercise on chronic pain and physical …

Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Draft Final Residential Metals Abatement Program (Rmap) (Non-Residential) - Interior School Dust - Investigation Summary Report–– Emerson Elementary (Dated October 13, 2023), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final Quarterly Operations And Maintenance Report Butte Treatment Lagoon System -Third Quarter 2022 (Dated November 16, 2023), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Of Berkeley Pit Predictive Water Level Model Letter; Dated January 24, 2024, Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Estrogen Signaling In The Dorsal Raphe Regulates Binge-Like Drinking In Mice, Valeria C Torres Irizarry, Bing Feng, Xiaohua Yang, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Hui Ye, Pei Luo, Leslie Carrillo-Sáenz, Penghua Lai, Maya Kota, Devin Dixit, Chunmei Wang, Amy W Lasek, Yanlin He, Pingwen Xu

Faculty, Staff and Students Publications

Estrogens promote binge alcohol drinking and contribute to sex differences in alcohol use disorder. However, the mechanisms are largely unknown. This study aims to test if estrogens act on 5-hydroxytryptamine neurons in the dorsal raphe nucleus (5-HTDRN) to promote binge drinking. We found that female mice drank more alcohol than male mice in chronic drinking in the dark (DID) tests. This sex difference was associated with distinct alterations in mRNA expression of estrogen receptor α (ERα) and 5-HT-related genes in the DRN, suggesting a potential role of estrogen/ERs/5-HT signaling. In supporting this view, 5-HTDRN neurons from naïve male mice had …