Digital Commons Network^™

Associations Between Anemia And Fgf23 In The Ckid Study., Elizabeth Thomas, Alexandra M. Klomhaus, Marciana L. Laster, Susan L. Furth, Bradley A. Warady, Isidro B. Salusky, Mark R. Hanudel

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that plays a central role in chronic kidney disease-mineral bone disorder and is associated with CKD progression and cardiovascular morbidity. Factors related to CKD-associated anemia, including iron deficiency, can increase FGF23 production. This study aimed to assess whether anemia and/or iron deficiency are associated with increased circulating concentrations of FGF23 in the large, well-characterized Chronic Kidney Disease in Children (CKiD) study cohort.

METHODS: Hemoglobin concentrations, iron parameters, C-terminal (total) FGF23, intact FGF23, and relevant covariables were measured in cross-sectional analysis of CKiD study subjects.

RESULTS: In 493 pediatric patients with …

Real-World Evidence On The Dosing And Safety Of C.E.R.A. In Pediatric Dialysis Patients: Findings From The International Pediatric Dialysis Network Registries., Laura Kohlhas, Milena Studer, Loes Rutten-Jacobs, Sylvie Meyer Reigner, Anja Sander, Hui-Kim Yap, Karel Vondrak, Paula A. Coccia, Francisco Cano, Claus Peter Schmitt, Bradley A. Warady, Franz Schaefer, Ipdn Collaborators

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: This retrospective real-world study used data from two registries, International Pediatric Peritoneal Dialysis Network (IPPN) and International Pediatric Hemodialysis Network (IPHN), to characterize the efficacy and safety of continuous erythropoietin receptor activator (C.E.R.A.) in pediatric patients with chronic kidney disease (CKD) on peritoneal dialysis (PD) or hemodialysis (HD).

METHODS: IPPN and IPHN collect prospective data (baseline and every 6 months) from pediatric PD and HD centers worldwide. Demographics, clinical characteristics, dialysis information, treatment, laboratory parameters, number and causes of hospitalization events, and deaths were extracted for patients on C.E.R.A. treatment (IPPN: 2007-2021; IPHN: 2013-2021).

RESULTS: We analyzed 177 patients …

Hypophosphatasia Diagnosis: Current State Of The Art And Proposed Diagnostic Criteria For Children And Adults., Aliya A. Khan, Maria Luisa Brandi, Eric T. Rush, Dalal S. Ali, Hatim Al-Alwani, Khulod Almonaei, Farah Alsarraf, Severine Bacrot, Kathryn M. Dahir, Karel Dandurand, Chad Deal, Serge Livio Ferrari, Francesca Giusti, Gordon Guyatt, Erin Hatcher, Steven W. Ing, Muhammad Kassim Javaid, Sarah Khan, Roland Kocijan, Agnes Linglart, Iman M'Hiri, Francesca Marini, Mark E. Nunes, Cheryl Rockman-Greenberg, Christian Roux, Lothar Seefried, Jill H. Simmons, Susan R. Starling, Leanne M. Ward, Liang Yao, Romina Brignardello-Petersen, E Michael Lewiecki

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: This manuscript provides a summary of the current evidence to support the criteria for diagnosing a child or adult with hypophosphatasia (HPP). The diagnosis of HPP is made on the basis of integrating clinical features, laboratory profile, radiographic features of the condition, and DNA analysis identifying the presence of a pathogenic variant of the tissue nonspecific alkaline phosphatase gene (ALPL). Often, the diagnosis of HPP is significantly delayed in both adults and children, and updated diagnostic criteria are required to keep pace with our evolving understanding regarding the relationship between ALPL genotype and associated HPP clinical features.

METHODS: An …

Audience Response To Covid Monologues: Research-Based Theater On The Societal Impact Of Covid-19, Emily A. Hurley, Saraniya Tharmarajah, Genevieve De Mahy, Jess Rassp, Joe Salvatore, Jonathan P. Jones, Steven A. Harvey

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Research-based theater uses drama to communicate research findings to audiences beyond those that typically read peer-reviewed journals. We applied research-based theater to translate qualitative research findings on the impact of the COVID-19 pandemic on different segments of U.S. society.

APPROACH: Theater artists and public health researchers collaborated to create a collection of eight monologues from systematically sourced, peer-reviewed publications. Following three virtual performances in Spring, 2021, audience members were invited to complete a survey.

SETTING/PARTICIPANTS: Audience survey respondents (n = 120) were mostly U.S.-based and were diverse in terms of age, race/ethnicity, gender, profession, and experience attending theater.

METHOD: …

Remote Delivery Of Allied And Behavioral Healthcare During Covid-19 For Children With Developmental Disabilities., Lisa D. Wiggins, Lin H. Tian, Sarah C. Tinker, Marshalyn Yeargin-Allsopp, Carolyn G. Diguiseppi, Cy Nadler, Patrick S. Powell, Eric J. Moody, Maureen S. Durkin, M Danielle Fallin, A Blythe Ryerson, Joann M. Thierry, Britney Robinson, Karen Pazol

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Many children with autism spectrum disorder (ASD) and other developmental disabilities (DD) transitioned to telehealth services due to the COVID-19 pandemic. Our objectives were to describe reductions in allied and behavioral healthcare services and receipt of caregiver training to deliver services at home because of COVID-19 for children with ASD and other DD, and factors associated with worse response to remote delivery of services for children with ASD.

METHOD: Prior to the pandemic, children 2 to 5 years of age were enrolled in a multi-site case-control study and completed a developmental assessment. Caregivers completed questionnaires on child behavior problems …

Racial And Ethnic Disparities In The Co-Occurrence Of Intellectual Disability And Autism: Impact Of Incorporating Measures Of Adaptive Functioning., Sarah M. Furnier, Ronald Gangnon, Julie L. Daniels, Susan Ellis Weismer, Cy Nadler, Karen Pazol, Nuri M. Reyes, Steven Rosenberg, Eric Rubenstein, Lisa D. Wiggins, Marshalyn Yeargin-Allsopp, Maureen S. Durkin

Manuscripts, Articles, Book Chapters and Other Papers

Intellectual disability (ID) commonly co-occurs in children with autism. Although diagnostic criteria for ID require impairments in both cognitive and adaptive functioning, most population-based estimates of the frequency of co-occurring ID in children with autism-including studies of racial and ethnic disparities in co-occurring autism and ID-base the definition of ID solely on cognitive scores. The goal of this analysis was to examine the effect of including both cognitive and adaptive behavior criteria on estimates of co-occurring ID in a well-characterized sample of 2- to 5-year-old children with autism. Participants included 3264 children with research or community diagnoses of autism enrolled …

Factors Affecting The Retention Of Active Duty Airmen, Gregory A. Picardi

Theses and Dissertations

This study investigates the factors influencing the early exit of active duty Airmen, particularly in the context of the recruitment challenges faced by the USAF in Fiscal Year 2023. The research highlights the significant impact of the implementation of MHS Genesis, a healthcare administration program, on recruitment processes and the broader issues affecting military recruitment, including physical and emotional trauma concerns among potential recruits. Through a survey conducted at Wright-Patterson Air Force Base involving 251 participants, the study utilizes a Chi-square test to explore the primary and secondary reasons for leaving active duty, with family pressure, stability, and financial reasons …

Analyzing Earned Value Management For Long Duration Development Efforts, Bradley L. Vuu

Theses and Dissertations

Earned Value Management (EVM) is an integral tool for the success of many programs by allowing the assessment of cost and schedule performance via its metrics. However, the accuracy of these metrics depends on programspecific factors such as phase and contract type. The purpose of this research is to analyze the stability of Estimates at Completion (EACs) for long duration development efforts. Prior research by Christensen in 1996 on EAC stability for development and production contracts was replicated by Kim, White, Ritschel, and Millette in 2019 and found differing results using modern data. This research found that for development efforts …

Life Cycle Analysis Of Mobile Nuclear Reactor Compared To Other Alternative Fuels In Indopacom, Maria J. Hurtado

Theses and Dissertations

Energy is an item that makes the military vulnerable as it is something that they depend on the most which can have negative impacts. Mobile nuclear reactors are gaining the interest of many leaders in the military as a viable option of a potential alternative fuel source. There are many positives in utilizing mobile nuclear reactors in terms of environmental impacts and feasibility of transport. Studies have shown that mobile nuclear reactors can produce very low or negligible carbon emissions during operations. The focus of this thesis is to determine the environmental impacts of nuclear reactors, logistical requirements, and determine …

Human Performance Modeling Architecture With Hc-130j Mission Application, Stephanie G. Slimp

Theses and Dissertations

The DOD emphasizes digital engineering using Model-Based Systems Engineering (MBSE), where MBSE includes SysML-based models of systems. Analysis of system impacts on the human operators and their performance typically occurs through non-MBSE approaches, if at all. One current process, considered the As-Is process for this research, evaluates human performance and workload using IMPRINT, a discrete event simulation (DES) tool. IMPRINT primarily exists as a standalone tool with limited built-in functionality to integrate with an MBSE tool. Using the HC-130J and its crew during a CSAR mission as the system, this research develops a generalizable and updateable human performance modeling architecture …

Mira Sussman, Oral History Interview, 2024, Cassandra Mitchell

Oral Histories

Mira Sussman is the Resource Development Manager for Jewish Family Services of Washtenaw County. In this interview, Sussman describes growing up in the Jewish community in Ann Arbor, her first time working at JFS in the employment program between 2005-2013, and how JFS evolved during her first time working there. Sussman explains how different resettlement services are at JFS now vs. the early 2000s, the resettlement process, and how COVID-19 has made resettling difficult due to lack of access to housing. Sussman also explores JFS’s collaboration with Eastern Michigan University in resettling 12 Afghan families into on-campus housing, storing mattresses …

Creating A Centralized Resource For Pediatric Pathology Cases, Shirley Jiang Md, Elsie S. Lee Md

USF-LVHN SELECT

No abstract provided.

Exploring Attitudes To Covid-19 Vaccination In A Rural Population, Nikhil C Reddy Md, Grant M. Greenberg M.D., M.H.S.A., M.A.

USF-LVHN SELECT

No abstract provided.

Feasibility Of Initiating A Screening, Testing, And Treatment Protocol For Pregnant Patients At High Risk For Obstructive Sleep Apnea (Osa), Kara Madey Md, Joanne Quiñones Md, Msce, Aileen L Love Md

USF-LVHN SELECT

No abstract provided.

Reevaluating Surgical Interventions In Childbirth For Women With Arnold Chiari Malformation Type I: A Systematic Review, Shalom Mussa Md, Kathryn Cheponis Md

USF-LVHN SELECT

No abstract provided.

Clinical And Genomic Correlates With Genetic Ancestry In Lung Squamous Cell Carcinoma, Sejal Jain Md, Alexander Yao, Fatemeh Momen-Heravi, Diane Allen-Gipson, Xiaoyang Zhang, Jian Carrot-Zhang, Alison Taylor

USF-LVHN SELECT

No abstract provided.

Differential Time From Diagnosis To Treatment Of Pulmonary Malignancy, Subin Paul Md, C. Gerard Petersen Md

USF-LVHN SELECT

No abstract provided.

Examining The Roles Of Erythropoietin And Melatonin In Preventing The Development Of Post-Hemorrhagic Hydrocephalus Of Prematurity, Sindhu Ramachandra, Lauren L. Jantzie, Shenandoah Robinson

USF-LVHN SELECT

No abstract provided.

Participation In Amputation Support Group On The Morbidity And Mortality Of Lower Extremity Amputation Patients, Karthik Pittala Md, Weston Terrasse Md, Ahmed Mansour Md, Nathan F. Miller Md

USF-LVHN SELECT

No abstract provided.

Grapheme-Color Synesthesia In Patients With Epilepsy, Snow Pinxue Li Md, Atef Kokash Do, Martina Vendrame Md, Phd

USF-LVHN SELECT

No abstract provided.

Initiation Patterns Of Anticoagulants For Atrial Fibrillation Among Older Uk Adults With And Without Chronic Kidney Disease, 2010-2020, Deborah Liaw Md, Julia Liaw, Chintan Dave

USF-LVHN SELECT

No abstract provided.

Select Anesthesiology Interest Group Needs Assessment And Quality Improvement, Brett O'Donnell Md, Thomas A. Mcloughlin Md

USF-LVHN SELECT

No abstract provided.

Health Fairs: A Community-Based Approach To Improving Health-Seeking Behaviors And Building Trust In The Healthcare System Among Patients In The Lehigh Valley, Fawaz Hussain Md, Fatima Pasha Md, Jonaid Aslam Md

USF-LVHN SELECT

No abstract provided.

Improving Health Literacy In The Lehigh Valley: Assessing The Role Of Health Fairs In Providing Education And Enhancing Understanding Of Diabetes, Hypertension, And Colon Cancer Screening, Fatima Pasha Md, Fawaz Hussain Md, Jonaid Aslam Md

USF-LVHN SELECT

No abstract provided.

Determining The Value Proposition Of Surgical Care In Cms Star Rated Hospitals, Konrad Cios, Hanroo Janjua, Michael Rogers, Meagan Read, Salvatore Docimo, Paul Kuo

USF-LVHN SELECT

No abstract provided.

Process Improvements For The Treatment Of Iron Deficiency Anemia In Pregnancy, Iris Kong Md, Natalie Chlus Md, Bradley Lash Md

USF-LVHN SELECT

No abstract provided.

Enhancing Trauma Patient Outcomes Through The Implementation Of An Acute Care Surgery Service Program, Clara Freedman Md, Joseph J. Stirparo Md

USF-LVHN SELECT

No abstract provided.

Sex Differences In Brain Mri Of Patients With Migraines, Y Su, S Singh, Victoria Qizhi Tay Md, Vitaliy Koss Md, Megan Leary Md, Hope Kincaid Mph, Cph, Hussam A. Yacoub Md, John Castaldo Md

USF-LVHN SELECT

No abstract provided.

Assessing Biological Condition Of Restored Streams In An Agriculturally Impaired Chesapeake Bay Sub-Watershed, Julia M. Portmann, Bruce Wiggins

Department of Biology - Faculty Scholarship

Intensive agricultural practices can be detrimental to aquatic biological conditions; however, restoration such as removing livestock and creating in-stream habitat can strengthen biotic communities. Smith Creek, a sub-watershed of the Chesa- peake Bay, was designated a showcase watershed in 2010 by the United States Department of Agriculture to demonstrate the efficacy of widespread restoration. Our study sought to follow up on these efforts by assessing the individual and combined impacts of restoration, habitat, and land cover on aquatic macroinvertebrate communities in Smith Creek. We predicted that longer-restored sites, sites with less surrounding pasture, and streams with larger substrate size would …

Himmelfarb Library Liaison Letter - March 2024, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Library Liaison Letters

No abstract provided.