A Quantitative Analysis Of Conscious Capitalism Effects On Gross Profit Margin Over Time, Alyssa Newsom, Arlene Ramkissoon, Douglas Ruml, Edward Lukco

Journal of the North American Management Society

Business is a vital part of American society, and the decisions made by businesses affect more than just the economy. Conscious Capitalism (CC) recognizes this important role, and it challenges businesses to operate in a responsible manner. CC recognizes the need to make a profit in order to succeed in a competitive market, and seeks to encourage profit by following four tenets of conscious business—conscious leadership, conscious culture, stakeholder orientation, and higher purpose— so that businesses attract customers and will experience increased profits over time. This study found that, while the gross profit margins of companies who practice CC were …

Working Remotely And Corporate Culture Wars In The Post-Pandemic Era, David M. Savino, Danielle C. Foster

Journal of the North American Management Society

Organizational culture is a sacred element of any organization. It is the lifeblood and the guiding force that makes each organization unique in its ability to navigate day-to-day and longer-term perspectives of corporate operations. Strong cultures help identify direction and philosophy and provide confidence in how to proceed to pursue innovative ideas and solve problems. Since 2020, the core value and the strength of many organizational cultures have been tested as a result of the increased reliance on working remotely and the adoption of a hybrid model of business operations not previously utilized to a great degree. While many survived …

Clinical And Procedural Characteristics Of Successful Transcatheter Device Closure Of Ostium Secundum Atrial Septal Defect In Symptomatic Children Weighing Less Than 15 Kg: A Retrospective Study Spanning One Decade From South India, Shobhit Priyanshu Joseph, Mirza Shohiab Ur Riyaz, Jesu Krupa, Shruti Irene Varghese, Gayathri Bhuvaneswaran Kartha, Oommen K. George, Paul V. George, John Jose, Viji Samuel Thomson

Journal of the Saudi Heart Association

Objectives: This retrospective study sought to determine the feasibility of transcatheter atrial septal defect device closure in patients less than 15 kg, as well as to assess complication rates and the reasons for unsuccessful device closure.

Background: In general, the risks associated with transcatheter atrial septal defect device closure are believed and reported to be relatively low, but the evidence stems from trials involving adults and older children. Current guidelines do not recommend atrial defect closure in device closure in children < 15kg, due to limited data available for feasibility and safety of device closure in this group of patients.

Methods: Retrospective review of all patients who underwent elective transcatheter closure of ostium secundum atrial septal defect between September …

Mid-Term Clinical And Hemodynamic Outcomes In Middle Age Patients Post Trifecta™ (Abbott) Aortic Valve Replacement: A Single-Center Study, Feras H. Khaliel, Mohammed Suliman Al Aboud, Suha A. Althibait, Saber Yezli, Elaf A Al Muaythir, Bandar Alamro, Domenico Galzerano

Journal of the Saudi Heart Association

Background: Trifecta™ is an externally wrapped bovine pericardial aortic valve with a favorable hemodynamic performance and acceptable rate of freedom from structural valve degeneration. However, recent reports of early Trifecta valve failure question its durability. Rheumatic valve disease in middle age population is predominant, there is no data on the Trifecta performance, durability or safety available worldwide over the middle age population, as well as there is no previous reports from Middle East region. We report on mid-term clinical and hemodynamic performance of Trifecta valve in middle age population with small aortic annuls, a single centre report. Methods: A retrospective …

Automating The Deprecation Of Logging Which Is Unused, Branden Archer, Pauline Anthonysamy

Defensive Publications Series

A method for optimizing a system for data logging using an optimization method and/or optimizer is proposed. The optimization method may autonomously detect and identify obsolete data logs and the corresponding data capture functionality for the obsolete data logs. The optimization method may then enact processes to remove the obsolete data and/or halt the capture and transmissions of such data from a client device. When compared to a traditional data logging system, the optimization method and/or optimizer may increase the efficiency and effectiveness of such a system.

Techniques To Facilitate Monitoring And/Or Management Of Different Environments Using Wireless Local Area Network Technologies, Janmejoy Das

Defensive Publications Series

There are a variety of scenarios in which it may be advantageous to monitor the location, operating conditions, environment, etc. for different locations at which people and/or equipment lab equipment may be located. Presented herein are techniques to facilitate monitoring and/or management of different environments, such as monitoring occupancy for workplace and/or public resource locations, monitoring health, safety, and/or operating conditions of lab equipment, among others, using wireless local area network (WLAN) technologies that can be used to interface with different sensors that may be provided in different environments. Data from the sensors can be collected via WLAN communications and …

Deficit-Oriented Language Use: Understanding The Effects Of Deficit-Oriented Labeling On First-Generation Students, Jeff Foulkes, Jeff Foulkes

Dissertations

Purpose: The purpose of this sequential mixed methods study was to describe how first- generation undergraduate college students perceive that deficit-oriented and strengths- based language has impacted them during their first year of study. A further purpose of this study was to identify how these students overcome the negative influences that are associated with deficit-oriented language.

Methodology: A sequential mixed methods research design was chosen to address the research questions for this study. Using a convenience sampling approach, the survey was disseminated to all first-year students in a specific program at a single university. Once the quantitative survey data were …

المعايير والتنظيمات المعمارية والعمرانية العالمية للإسكان التشاركي, Saeed Ali Alburgawi, Ali Salem Bahammam Prof

Emirates Journal for Engineering Research

انتشر الإسكان التشاركي حول العالم، بسبب مرونة المنصات الإلكترونية للحجوزات وما تتيحه من تنوع في الخيارات. وقد أدى انتشاره إلى ظهور أنماط متعددة، تتسم ببعض الصفات المشتركة، وتختلف في بعض التفاصيل وآليات التطبيق وطريقة التنظيم. إلا أن سرعة الانتشار أدت في المقابل إلى تهميش الرقابة والتنظيم الرسميين للإسكان التشاركي، مما يستدعي الحاجة إلى تطوير تنظيمات ومعايير معمارية وعمرانية تتلاءم مع تزايد الطلب على الإسكان التشاركي.

لقد كان الإسكان التشاركي، إلى ما قبل ثلاثة عقود تقريباً، أحد أنماط إسكان ضيوف الرحمن في مكة المكرمة. ويُعد إعادة تفعيله بأسلوبه المعاصر، بديلاً مناسب لإسكان المعتمرين، كونه يساهم في تحقق بعض الركائز الاستراتيجية لبرنامج …

Cutaneous Ulcerations As The Presenting Sign Of Acute Aortic Occlusion, Odera Ekeh, Zoe I. Smith, Justin J. Green

Cooper Medical School of Rowan University Departmental Research

This is a report of a case of acute aortic occlusion (AAO) in a 46-year-old woman who presented with confluent and coalescing punched-out ulcerations on the bilateral medial buttocks and abdominal ulcerations. This case highlights how AAO, although rare, should be considered in patients with cardiovascular risk factors presenting with acute lower extremity pain and new-onset cutaneous ulcerations of the perineum and/or abdomen.

A Multi-Omics Investigation Into The Mechanism Of Action Of An Anti-Tubercular Fatty Acid Analog, Isin T. Sakallioglu, Amith S. Maroli, Aline De Lima Leite, Darrell D. Marshall, Boone W. Evans, Denise K. Zinniel, Patrick H. Dussault, Raul G. Barletta, Robert Powers

Patrick Dussault Publications

The mechanism of action (MoA) of a clickable fatty acid analogue 8-(2-Cyclobuten-1-yl)octanoic acid (DA-CB) has been investigated for the first time. Proteomics, metabolomics, and lipidomics were combined with a network analysis to investigate the MoA of DA-CB against Mycobacterium smegmatis (Msm). The metabolomics results showed that DA-CB has a general MoA related to that of ethionamide, a mycolic acid inhibitor that targets enoyl-ACP reductase (InhA), but DA-CB likely inhibits a step downstream from InhA. Our combined multi-omics approach showed that DA-CB appears to disrupt the pathway leading to the biosynthesis of mycolic acids, an essential mycobacterial fatty acid …

The Impact Of Social-Emotional Competence On Academic Achievement And Career Success Within Urban School Systems, Lashanda R. Boone, Keesha Byrd, Susan Grimes, Jamesha Purdiman, Cierra Wourman

Dissertations

Abstract

This dissertation investigates the critical role of social-emotional learning (SEL) in urban education through the lens of educators working in a diverse middle school setting in St. Louis, Missouri. With a focus on understanding educators' perceptions and experiences, this study aims to explore the effectiveness of SEL programs in addressing the various needs of students, particularly those from marginalized communities. The researchers use a qualitative approach, utilizing surveys with open-ended questions to gather insights from middle school teachers, counselors, support staff, and administrators. The study dove into various aspects of SEL implementation through rigorous data collection and analysis, including …

Discovering Italian Chicory, Jean Lavigne

Environmental Studies Faculty Publications

No abstract provided.

Remodeling Anaplastic Thyroid Cancer's Aggressive Profile And Metabolic Signature By Natural Alkaloid Berberine, Tara Elizabeth Jarboe

NYMC Student Theses and Dissertations

Anaplastic thyroid cancer is a rare, fatal cancer with a five-year survival of 4%. Universally diagnosed at stage IV, anaplastic thyroid cancer is characterized by its lack of differentiation, rapid proliferative rate, highly inflammatory tumor microenvironment, and metabolic dysregulation. Refractory to all established therapies, anaplastic thyroid cancer requires a novel therapeutic approach that targets all of these drivers of anaplastic thyroid cancer carcinogenesis. We propose natural alkaloid berberine as a therapeutic with multitarget efficacy to alter mitochondrial metabolism and reprogram anaplastic thyroid cancer’s aggressive phenotype. Our in vitro model uses monocyte cell line U937, anaplastic thyroid cancer cell lines T238 …

Standardized Patient Overlays In Undergraduate Nursing Simulation To Improve Clinical Competency, Vivian Bowman

SACAD: Scholarly Activities

Nurse educators use simulation as a tool to teach and evaluate clinical skills. The opportunities have expanded with the advancement of new technologies related to high-fidelity (HFS) simulation. However, HFS has limitations, as there is a lack of meaningful two-way communication. During the last 10 years, educators have increased the usage of standardized patients (SPs) in simulation experiences. SPs can add realism to a simulation, providing nonverbal cues and psychological responses that a manikin cannot produce. Hybrid simulation further enhances the SP experience by incorporating a wearable overlay, such as a tracheostomy, urinary catheterization, or chest tube care simulator. This …

2024 March 18 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

Historical Analogy And The Role Morality Of Reason-Giving, Darrell A. H. Miller

Duke Law Journal Online

The Supreme Court has turned ever more to analogical reasoning from history and tradition to decide significant matters of public policy. Nowhere is this phenomenon more evident than in the Court’s 2022 decision in New York State Rifle and Pistol Association v. Bruen.

The Court’s crafting of a Second Amendment test that turns almost entirely on the strength of analogies—and on a topic of such intense public salience—has thrust analogical reasoning to the forefront of judicial and academic debate. While many have questioned the workability of Bruen’s focus on historical analogs, this Essay is less concerned about the pragmatics of …

The Utah Statesman, March 18, 2024, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Optimizing "Open Data Jawa Tengah" Through Technology Acceptance Model (Tam), Yasykur Hisyam Muáafii False, Priyanto Priyanto False

Elinvo (Electronics, Informatics, and Vocational Education)

The Central Java Provincial Government has implemented the “Open Data Jateng” system since 2019 for public services. Open Data is part of the application of big data, and the system does not yet have evidence to meet data needs. So, an explanatory method of research was conducted using a prediction study. The research variables are based on the development of the Technology Acceptance Model (TAM) theory and the 3Q model theory. 130 respondents from the exKaresidenan of Semarang City filled out 21 statements, then tested through Partial Least Square - Structural Equation Modeling (PLSSEM). The result is that there is …

Point Of View On Outcome Prediction Models In Post-Stroke Motor Recovery, Onno Van Der Groen, Manonita Ghosh, Richard Norman, Amy Kuceyeski, Ceren Tozlu, Teresa J. Kimberley, David J. Lin, Laurel J. Buxbaum, Gert Kwakkel, Steven C. Cramer, Dylan J. Edwards

Moss-Magee Rehabilitation Papers

Stroke is a leading cause of disability worldwide which can cause significant and persistent upper limb (UL) impairment. It is difficult to predict UL motor recovery after stroke and to forecast the expected outcomes of rehabilitation interventions during the acute and subacute phases when using clinical data alone. Accurate prediction of response to treatment could allow for more timely and targeted interventions, thereby improving recovery, resource allocation, and reducing the economic impact of post-stroke disability. Initial motor impairment is currently the strongest predictor of post-stroke motor recovery. Despite significant progress, current prediction models could be refined with additional predictors, and …

Week Of March 18, 2024, Student Life

College, School and Department Newsletters, Magazines, and Journals

Your weekly hub for events, resources and updates.

Modulation Of Hippocampal Protein Expression By A Brain Penetrant Biologic Tnf-Α Inhibitor In The 3xtg Alzheimer’S Disease Mice, Nataraj Jagadeesan, G. Chuli Roules, Devaraj V. Chandrashekar, Joshua Yang, Sanjana Kolluru, Rachita K. Sumbria

Pharmacy Faculty Articles and Research

Background

Biologic TNF-α inhibitors (bTNFIs) can block cerebral TNF-α in Alzheimer’s disease (AD) if these macromolecules can cross the blood–brain barrier (BBB). Thus, a model bTNFI, the extracellular domain of type II TNF-α receptor (TNFR), which can bind to and sequester TNF-α, was fused with a mouse transferrin receptor antibody (TfRMAb) to enable brain delivery via BBB TfR-mediated transcytosis. Previously, we found TfRMAb-TNFR to be protective in a mouse model of amyloidosis (APP/PS1) and tauopathy (PS19), and herein we investigated its effects in mice that combine both amyloidosis and tauopathy (3xTg-AD).

Methods

Eight-month-old female 3xTg-AD mice were injected intraperitoneally with …

Usa V. Roman Murray

2024 Decisions

USDC for the Middle District of Pennsylvania

The Experience Of Grief, Coping, And Community In Black Families And Friends Of Homicide Victims, Rachel A. Jenkins

Walden Dissertations and Doctoral Studies

No abstract provided.

Leveraging The Hmbc To Facilitate Metabolite Identification, Fatema Bhinderwala, Thao Vu, Thomas G. Smith, Julian Kosacki, Darrell D. Marshall, Yuhang Xu, Martha D. Morton, Robert Powers

Department of Chemistry: Faculty Publications

The accuracy and ease of metabolite assignments from a complex mixture are expected to be facilitated by employing a multi-spectral approach. The 2D ¹H-¹³C HSQC and 2D ¹H-¹H-TOCSY are the experiments commonly used for metabolite assignments. The 2D ¹H-¹³C HSQC-TOCSY and 2D ¹H-¹³C HMBC are routinely used by natural products chemists but have seen minimal usage in metabolomics despite the unique information, the nearly complete ¹H-¹H and ¹H-¹³C and spin systems provided by these experiments that may improve the accuracy and reliability …

Delayed Diagnosis Of Mycobacterium Bovis Bacillus Calmette-Guérin Periprosthetic Joint Infection Following Total Knee Arthroplasty, Christopher E. Pelt, Salika Shakir, Michael J. Cahill, Jakrapun Pupaibool, Barbara C. Cahill

SKMC Student Presentations and Publications

Periprosthetic joint infection (PJI) can present challenges in diagnosis and treatment, particularly in the setting of atypical causative organisms such as fungi and mycobacteria. Herein, we present a case and provide a review of the diagnosis and treatment of an unusual PJI caused by bacillus Calmette-Guérin, administered during the treatment of bladder cancer 3 years prior to total knee arthroplasty and subsequent PJI. Although the patient's history of bladder cancer was known, neither his Bacillus Calmette-Guérin treatment nor its potential for distant site spread that could lead to PJI were appreciated, leading to a prolonged diagnostic evaluation and treatment course.

4 Art, Fashion, And The Human Condition, Fuat Firat

Marketing Faculty Publications

In this chapter, I wish to investigate the contemporary status and role of art and fashion together with the conditions that humanity faces resulting from modern constructions of art and fashion. I begin with the understanding that, as is the case with all concepts, art and fashion do not have a meaning that endures across all historical epochs or cultural contexts, even when they may possess some essences that make it possible to have a degree of continuity of popular conception across time and context. In each epoch and in every culture, however, they take on certain particularities imbued in …

The Wage Of Wellness: The Relationship Between Socioeconomic Status, Race, And Work Recovery, Emily Julia Ready

Dissertations and Theses

A substantial share of the workforce is made up of low-income workers. Many of these workers fall below the federal poverty line and are considered low socioeconomic status (SES) and are disproportionately more likely to be racial minorities. However, this population is often neglected in the industrial-organizational psychological literature. Specifically, work recovery research has not considered the unique life circumstances of this particular group in the development of the research questions, theoretical framework, or practical implications in relation to this phenomenon. The purpose of the current study is to understand the relationship between socioeconomic status, race, and work recovery experiences …

The Prevalence Of Gram-Negative Bacteria With Difficult-To-Treat Resistance And Utilization Of Novel Β-Lactam Antibiotics In The Southeastern United States, Y. Vivian Tsai, P. Brandon Bookstaver Pharm.D., Joseph Kohn, Julie Ann Justo, Darrell Childress, Stefanie Stramel, Douglas Slain, Patrick Tu, Mary Joyce B. Wingler, Bruce M. Jones, Daniel T. Anderson, Megan M. Seddon, David A. Cretella, Joshua Eudy, Hana Winders, Kayla Antosz Pharm.D., Pamela Bailey, Majdi N. Al-Hasan

Faculty Publications

Objective:

To evaluate temporal trends in the prevalence of gram-negative bacteria (GNB) with difficult-to-treat resistance (DTR) in the southeastern United States. Secondary objective was to examine the use of novel β-lactams for GNB with DTR by both antimicrobial use (AU) and a novel metric of adjusted AU by microbiological burden (am-AU). Design:

Retrospective, multicenter, cohort. Setting:

Ten hospitals in the southeastern United States. Methods:

GNB with DTR including Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. from 2015 to 2020 were tracked at each institution. Cumulative AU of novel β-lactams including ceftolozane/tazobactam, ceftazidime/avibactam, meropenem/vaborbactam, imipenem/cilastatin/relebactam, and cefiderocol in days of therapy (DOT) …

Dr. Nick Elam Selected For The 2024 Doris Drees Speaker Series, University Of Dayton. School Of Education And Health Sciences

School of Education and Health Sciences Blog Archive

The two-time UD alumnus and inventor of basketball's Elam Ending will be the guest speaker for the health and sport science annual student awards.

Brain-Specific Serine/Threonine-Protein Kinase 1 Is A Substrate Of Protein Kinase C Epsilon Involved In Sex-Specific Ethanol And Anxiety Phenotypes, Michael P. Dugan, Rajani Maiya, Caleb Fleischer, Michal Bajo, Angela E. Snyder, Ashwin Koduri, Sathvik Srinivasan, Marisa Roberto, Robert O. Messing

School of Graduate Studies Faculty Publications

Protein kinase C epsilon (PKCε) regulates behavioural responses to ethanol and plays a role in anxiety-like behaviour, but knowledge is limited on downstream substrates of PKCε that contribute to these behaviours. We recently identified brain-specific serine/threonine-protein kinase 1 (BRSK1) as a substrate of PKCε. Here, we test the hypothesis that BRSK1 mediates responses to ethanol and anxiety-like behaviours that are also PKCε dependent. We used in vitro kinase assays to further validate BRSK1 as a substrate of PKCε and used Brsk1−/− mice to assess the role of BRSK1 in ethanol- and anxiety-related behaviours and in physiological responses to ethanol. We …