Digital Commons Network^™

From Eighty Acres And A Mule To Two Thousand Acres And Twenty-Four Row Planters: Anxieties Of Growth In The Agriculture Sector From Family Farms, Riley Marie Francis

Theses and Dissertations

This study investigates the evolution of the family farm between the 1940s until the 2020s, and how the family farm may continue to evolve in future generations. The aim of this study is to investigate the relationship between the changing reality of agriculture and how farmers think about themselves. In the early days of the United States republic, farms were a means of providing a family or localized community with food and resources. These farms participated in an economic exchange that was an early form of capitalism, characterized by meeting needs but not accruing egregious excess. Today’s agricultural system is …

Outcomes For Individuals Born Outside Of Marriage, Kathryn Dawn Keithley

Theses and Dissertations

This paper examines the effect of being born outside of marriage (BOOM) on the future outcomes of individuals. I use the Panel Study of Income Dynamics (PSID) individual-level data to follow individuals from birth to age 30 and analyze the effect of being born outside of marriage on future marital status, education level, and poverty status. I find statistically significant impacts of BOOM on future outcomes, though additional childhood controls lessen the effect. I then use arguably exogenous variation from the marital status of an individual’s grandmother at the time of their mother’s birth to instrument for external factors that …

S ( M ) Othering: A Rhetorical Analysis Of Republican Motherhood, Caroline King

Theses and Dissertations

This study examines seven Republican rhetors who utilize motherhood as a rhetorical strategy in speeches between the years of 1972 and 2020. Specifically, speeches, newsletters, and debate transcripts are analyzed using four theoretical lenses to curate an archetype of the “Republican Mother” – a concept constructed of an amalgamation of the historic “mother of the republic” from the nation’s conception and the ideological values assigned to women within the Republican party, such as traditional gender and spousal roles. I argue that it is the unique combination of womanhood, motherhood, and Republicanism that creates a unique rhetorical strategy seen in these …

Post-High School Trajectories Of Filipino American Students: The Role Of Communication, Kathryn Anne Mayer

Theses and Dissertations

This study actively explores the intricate influences shaping the educational and career trajectories of Filipino American students post-high school. Through qualitative interviews and thematic analysis, it unveils the intricate web of familial expectations, financial constraints, personal values, and external pressures shaping their educational and career pathways. By actively addressing research questions concerning the factors informing choices and the process of weighing competing messages, this research offers nuanced insights. It illuminates the dynamic decision-making processes within the Filipino American community, emphasizing the necessity for tailored interventions and support mechanisms. By actively engaging with these findings, this study contributes to enhancing the …

Peer Cybervictimization ( Pcv ) Among University Students In Bangladesh And Institutional Disciplinary Body ( Idb ) Under Routine Activity Theory ( Rat ), Selimul Quader

Theses and Dissertations

Research on cybervictimization of Bangladeshi students is scarce, but the research that does exist suggests a high prevalence of victimization followed by low extent of reporting. None of the extant research exclusively studied peer cybervictimization (PCV) in relation to students’ knowledge of the university authority, hereinafter the institutional disciplinary body or IDB. As per the added propositions of Routine Activity Theory (RAT) (Felson, 1995), the IDB can potentially contribute to guardianship building by alerting students about handlers-managers in the university premises and thereby reduce PCV among students. Thus, the knowledge of (the presence of) the IDB can respond to the …

Acculturation Strategy Of The First-Generation Immigrants: A Study On The Muslim Parents In The United States, Eshrat Rahman

Theses and Dissertations

This study aims to investigate the acculturation strategy of the first-generation immigrant Muslim parents in the US. This study is guided by segmented assimilation theory and data for the study was collected by employing qualitative research method. I conducted in-depth interview with twelve first-generation Muslim immigrant parents in the McLean County, Illinois to collect data for the study. The participants responded to a number of open-ended questions relating their cultural and Muslim identity, practice of their Islamic faith in your family and outside and raising their children in a different cultural environment. The finding of this study shows that the …

The Rider (2024-03-25), Natalie Lapsley

The Rider Archives

Vol.9 No.24

Tmem106b Coding Variant Is Protective And Deletion Detrimental In A Mouse Model Of Tauopathy, George A Edwards, Caleb A Wood, Yang He, Quynh Nguyen, Peter J Kim, Ruben Gomez-Gutierrez, Kyung-Won Park, Yong Xu, Cody Zurhellen, Ismael Al-Ramahi, Joanna L Jankowsky

Duncan NRI Faculty and Staff Publications

TMEM106B is a risk modifier of multiple neurological conditions, where a single coding variant and multiple non-coding SNPs influence the balance between susceptibility and resilience. Two key questions that emerge from past work are whether the lone T185S coding variant contributes to protection, and if the presence of TMEM106B is helpful or harmful in the context of disease. Here, we address both questions while expanding the scope of TMEM106B study from TDP-43 to models of tauopathy. We generated knockout mice with constitutive deletion of TMEM106B, alongside knock-in mice encoding the T186S knock-in mutation (equivalent to the human T185S variant), and …

The Free Press Vol. 55, Issue 9, 03-25-2024, Dakota Eddy

Free Press, The

The New FAFSA: Q&A--Games and Activities--Maine Marches for Gaza--USM Hosts Banned Book Fair with Books=A=Million--Volunteering At Preble Street--University of Southern Maine Men's Lacrosse Battles UNE Nor'easters

Improving The Accuracy Of Medical Records In Healthcare Institutions, Tarkessa Frazier

Walden Dissertations and Doctoral Studies

No abstract provided.

Quality Of Life After A Prostatectomy In Men Who Have Sex With Men, Jéaux Alexander Rinedahl

Walden Dissertations and Doctoral Studies

No abstract provided.

Impact Of The Lived Experience Of Adverse Childhood Experiences On Adult Homelessness, Arlene Marcellette Smith

Walden Dissertations and Doctoral Studies

No abstract provided.

Single Mother Leaders Improving Organizational Employees’ Good Health And Well-Being During The Covid-19 Pandemic, Emmanuel Ifeoma Nwogor

Walden Dissertations and Doctoral Studies

No abstract provided.

Numerical Simulation On Influence Of Skin Effect On Groundwater Flow Velocity In Wellbore, Wang Qihang, Li Xu, Guo Qiang, Kuai Dawei

Coal Geology & Exploration

Groundwater flow velocity in wellbore is usually measured by single-well tracking tests or Aqua Vision flow velocity and direction meters to calculate the groundwater flow velocity in the aquifer. Due to the impact of the skin structure, the groundwater flow field near the wellbore changes, causing a difference between the flow velocity in the wellbore and that in the aquifer. In order to investigate the influence of the skin effect on the groundwater flow velocity in the wellbore, a numerical model of groundwater flow that considers the skin effect was established using the COMSOL Multiphysics software. On this basis, the …

Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Affects Nitrate Metabolism, But Not Vascular Function Or Blood Pressure In Older Adults With Hypertension, Rebeka Fejes, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Karl-Heinz Wagner, Hans-Peter Stüger, Jonathan M. Peake, Richard J. Woodman, Kevin D. Croft, Catherine P. Bondonno, Jonathan M. Hodgson, Michael Wolzt, Oliver Neubauer

Research outputs 2022 to 2026

The decline in vascular function and increase in blood pressure with aging contribute to an increased cardiovascular disease risk. In this randomized placebo-controlled crossover study, we evaluated whether previously reported cardiovascular benefits of plant-derived inorganic nitrate via nitric oxide (NO) translate into improved vascular function and blood pressure-lowering in 15 men and women (age range: 56-71 years) with treated hypertension. We investigated the effects of a single ∼400 mg-dose at 3 hours post-ingestion (3H POST) and the daily consumption of 2 × ∼400 mg of nitrate through nitrate-rich compared with nitrate-depleted (placebo) beetroot juice over 4 weeks (4WK POST). Measurements …

U'Wa Indigenous People Vs. Columbia: Potential Applications Of The Escazu Agreement, Ariana Lippi

Sustainable Development Law & Policy

Though the case is ongoing, and results are still to be seen, it in many ways sets a precedent for indigenous communities in Latin America seeking redress for environmental and cultural injustices. With Colombia’s recent ratification of The Escazú Regional Agreement (the Agreement herein) in 2022, this case presents a unique opportunity for implementation of the Agreement and greater accountability within existing domestic legislation.

Natural Resources In The Arctic: The Equal Distribution Of Uneven Resrouces, Ganeswar Matcha, Sudarsanan Sivakumar

Sustainable Development Law & Policy

This paper analyses the governance machine in place at the Arctic and examines the application of the principles of “common heritage of mankind” at the Arctic. This paper also offers some tentative propositions aimed at protecting Out Bound investment rights and how the World Trade Organization or other countries, like the U.S., can intercede in the Arctic investment sphere and attempt to regulate along with the United Nations Convention for the Law of the Sea.

Incentivizing Sustainability In American Enterprise: Lessons From Finnish Model, Vasa T. Dunham

Sustainable Development Law & Policy

The disparate climate performances of Finland and the United States, two of the wealthiest countries in the world, bring to light the question of how corporate responsibility has been inspired in each jurisdiction. Having established the urgency of the climate crisis and the importance of corporate behavior in optimizing a given country’s approach to protection of the global environment, an examination of each nation’s legal frameworks may shed light on features of the corporate regime that are effective in advancing sustainability goals and those that are not.22 Part I of this paper establishes a comparative framework by providing background on …

Editor's Note, Shade Streeter, Reagan Ferris

Sustainable Development Law & Policy

The Sustainable Development Law & Policy Brief (ISSN 1552-3721) is a student-run initiative at American University Washington College of Law that is published twice each academic year. The Brief embraces an interdisciplinary focus to provide a broad view of current legal, political, and social developments. It was founded to provide a forum for those interested in promoting sustainable economic development, conservation, environmental justice, and biodiversity throughout the world.

What Time Is It? It Is 8-And-A-1/2 Time. A Rare Case About Right Medial Pontine Stroke, Right Ino, Right Facial Colliculus Ischemic Stroke Consistent With Eight-And-A-Half Syndrome., Jessica Marcela Daza, Eunbee Cho, Celia Patricia Daza, Shakirat Ganiyu, Francisco Gomez

Research Symposium

Eight-and-a-half syndrome (EHS) is a rare neuro-ophthalmologic condition characterized by conjugated horizontal gaze palsy, internuclear ophthalmoplegia (INO), and ipsilateral fascicular seventh cranial nerve palsy. Clinical features are attributed to the involvement of the lower pontine, including the abducens nucleus, ipsilateral medial longitudinal fasciculus (MLF), and adjacent facial colliculus. Etiology includes vascular diseases such as pontine infarction or ischemia, demyelinating conditions at the level of the pons, and rarely space-occupying lesions.

Β-Cyclodextrin-Enzalutamide Self-Assembly Complexes For Prostate Cancer Therapy, Meghana Kolli, Rahul Tiwari, Subhash C. Chauhan, Yonghong Zhang, Neeraj Chauhan, Alba C. M, Murali Yallapu

Research Symposium

Background:Castrate circumstances brought on by therapy give rise to castrationresistant prostate cancer (CRPC), which thereafter develops androgen receptor (AR) resistance. AR inhibitors are frequently used to obstruct AR translocation in cells that overexpress AR and slow the progression of cancer by reducing the number of AR receptors that are accessible. In comparison to Bicalutamide, a first-generation AR inhibitor, the hydrophobic drug Enzalutamide has demonstrated higher effectiveness. We investigate Enzalutamide as a viable option for the formation of self-assembly complexes because AR downregulation is still the major treatment for CRPC.

Methods:Enz-loaded self-assembly complexes (enz-β-CD) formulation was developed using solvent …

Update On The Role Of Muc13 In Pancreatic Cancer: A Promising Early Detection Biomarker, Anupam Dhasmana, Swati Dhasmana, Sheema Khan, Meena Jaggi, Murali M. Yallapu, Subhash C. Chauhan

Research Symposium

Background: With the rise in pancreatic cancer (PanCa) prevalence and mortality rate, by 2030 it will secure second position among leading causes of cancer-related deaths. Due to poor prognosis of PanCa only 11% of PanCa patients have a 5-year survival rate, resulting in an equal mortality rate and incidence rate. 85% of PanCa are Pancreatic ductal adenocarcinoma (PDAC). The main clinical challenge with PanCa is poor treatment outcomes due the late diagnosis. Currently, there are traditional biomarkers panels available for diagnosis, however, these biomarkers do not have optimal sensitivity and specificity for PanCa. Considering this alarming unmet clinic need, our …

Unveiling The Influence Of Transcription Factor Yb1 In Hepatocellular Carcinoma Cell Lines, Yamile Abuchard, Sophia Leslie, Dennis Kwabiah, Ricardo Pequeno Bracho, Ana Ayala Pazzi, Mohammad Hussain, Manish Tripathi

Research Symposium

Background: In the Rio Grande Valley (RGV), Hispanics constitute the predominant ethnic group, accounting for over 94% of the population. Projections for 2023 indicate liver cancer to rank fifth in male and seventh in female mortality. Hepatocellular carcinoma (HCC) manifests as a significant concern within the Hispanic community, influenced by a spectrum of factors—biogenetic, social, and cultural—that intertwine with genetic predispositions and dietary practices. The incidence of HCC is intertwined with various illnesses like hepatitis, liver cirrhosis, drug-induced liver injury (DILI), adding to the burden of cancer. Over the years, HCC prevalence in the RGV has surged by over 35%. …

Unraveling Sorafenib Resistance In Hepatocellular Carcinoma: Exploring Key Facets, Dennis Kwabiah, Kyle Doxtater, Yamile Abuchard, Sophia Leslie, Ricardo Pequeno Bracho, Shaibir Hussain, Manish K. Tripathi

Research Symposium

Hepatocellular carcinoma (HCC) stands as the prevalent form of primary liver cancer worldwide, diagnosing over half a million new cases annually. Surgical interventions like hepatectomy and liver transplantation offer a potential cure for early-stage HCC. However, the prognosis for advanced stages remains grim due to drug resistance, particularly with high refractoriness rates. Sorafenib, a tyrosine kinase inhibitor, is an approved treatment for advanced HCC. Despite its use, the overall survival extension for these patients remains limited due to the drug's ineffectiveness, and the mechanism behind advanced HCC's resistance to sorafenib remains elusive. TCGA analysis of HCC patient cohorts reveals elevated …

Too Yellow: An Idiopathic Case Of Autoimmune Hemolytic Anemia, Shreel Patel, Kashif Ali, Donnel Dockery-Joseph, Eunbee Cho, Sriharsha Koneru, Taha Al Hassan, Aramide Tijani, Elimar Gonzalez Morales

Research Symposium

Background: Autoimmune hemolytic anemia is caused by autoantibodies that react with self red blood cells and cause them to be destroyed. Warm AIHA, due to antibodies that are active at body temperature, is the most common type of the AIHA. It is mostly caused by the underlying disease like infections, autoimmune disorders, lymphoproliferative disorders, immunodeficiency or physiologic state like pregnancy. Rarely it happens that there is no underlying cause. Therefore, here we present a case of idiopathic autoimmune hemolytic anemia without any underlying cause.

Case Discussion: A 77 year old lady with known history of the diabetes mellitus type 2, …

Trimeric Antp-Tbp Complexes With Tfiieβ And Exd Modulated The Transcriptional Activity Of Antp, Norma C. Hernández-Bautista, Claudia A. Altamirano-Torres, Ruben Montalvo Mendez, Gustavo Jiménez-Mejía, Diana Reséndez-Pérez

Research Symposium

Homeoproteins are transcription factors that bind to DNA through a highly conserved binding domain known as the homeodomain (HD), which recognizes short regions rich in A-T. This DNA binding triggers the modulation of multiple target genes responsible for identity in various structures along the A-P axis of D. melanogaster. However, the high similarity of homeodomains and their affinity for widely distributed sites in the genome poses the "Hox paradox," which seeks to explain how homeoproteins acquire functional specificity so precisely. Previous evidence shows that homeoproteins like Antennapedia (Antp) form dimers with cofactors and other transcription factors to modulate their …

The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama

Research Symposium

Background: Periodontal disease (PD), affecting 20-50% of the global population is marked by biofilm-induced inflammation in oral tissues. Chronic PD results in systemic complications such as heart disease, stroke, and Alzheimer's. The red complex microbes, Porphyromonas gingivalis and Treponema denticola, play a pivotal role, penetrating the blood-brain barrier and contributing to neurodegeneration. Alzheimer's disease (AD), an irreversible neurodegenerative disorder, is linked to abnormal protein cleavage and potentially involves microbiologic components, including gram-positive cocci. Research suggests the presence of bacteria such as Porphyromonas, Actinomyces, and Treponema in autopsied AD brains. Investigating the microbiologic connection between PD and AD is crucial, considering …

The Role Of Age And Biological Sex On Short-Term Memory In The Syrian Hamster (Mesocricetus Auratus), Laura E. Garcia, Mario Gil

Research Symposium

Background: Aging plays an important role in cognitive function, memory, and mental health. As we age, some cognitive functions become weaker. Aging is also a critical risk factor for dementia and Alzheimer’s Disease. With recent advances seen in public health, humans are living longer years. This makes it a challenge to make those added years healthy. For this reason, it is important to continue studying its effects by using, the Syrian hamster, as a model. The purpose of the study is to identify other factors that might also have a role in short-term memory, besides aging.

Methods: All behavioral …

Patterns Of Social Responsibility Among Gifted Students And Their Relationship To Certain Variables, Suhair Al-Tal, Fuad Al-Jawaldeh, Heyam Al-Taj, Wafaa Al-Eid

Jordan Journal of Applied Science-Humanities Series

The current study aimed to identify the degree of prevalence of social responsibility patterns among gifted students in schools in Cairo during the second semester of the academic year 2019/2020. The study sample consisted of 196 male and female students from grades eight and ten, all of whom achieved an average of 90% or higher. The sample included 102 female students and 94 male students. The researchers developed and applied a social responsibility scale encompassing three patterns: self, family, and social, after verifying its validity and reliability. The results indicated that the prevalence of social responsibility patterns among gifted students …

The Impact Of Corporate Governance On Organizational Citizenship Behavior In Jordanian Insurance Companies, Sanaa Al-Awamleh, Shaker Al-Khashali

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the impact of corporate governance on the organizational citizenship behavior of Jordanian insurance companies. The study was based on five dimensions of corporate governance: Disclosure, Justice, Responsibility, Independence, and Accountability, along with five dimensions of organizational citizenship behavior: Altruism, Courtesy, Sportsmanship, Conscientiousness, and Civic Virtue. The study population included 403 managers in upper and middle management positions within Jordanian insurance companies. A random stratified sampling method was adopted to represent the study population. Out of the distributed questionnaires, 191 were sent, and 156 were retrieved. The researchers utilized several statistical methods to analyze the study …