Digital Commons Network^™

Progressive Arm Cycling Ergometry With 3- And 5-Minute Stage Durations Yields Similar Estimates Of Substrate Oxidation In Healthy Adults, Todd A. Astorino Ph.D, Zachary Jordan, Cristian Gonzales, Carly Schuerger, Muhammed M. Atakan

International Journal of Exercise Science

International Journal of Exercise Science 17(2): 468-479, 2024. Arm cycling ergometry (ACE) leads to a lower maximal oxygen uptake (VO₂max) than cycling which is related to a smaller active muscle mass. This study compared estimates of fat and carbohydrate oxidation (FOx and CHOOx) between progressive exercise protocols varying in stage duration in an attempt to create a standard exercise protocol for determining substrate metabolism using ACE. Four men and seven women (age = 24 ± 9 yr) unfamiliar with ACE completed incremental exercise to determine peak power output and VO₂peak. During two subsequent sessions completed after …

Influence Of Physical Activity Including Squat Exposure On Trunk Muscle Strength And Labour Outcome In Pregnant Women, Rajal Savla, Rajani Mullerpatan, Bela Agarwal, Victoria Kuttan, Sushil Kumar

International Journal of Exercise Science

International Journal of Exercise Science 17(1): 504-516, 2024. Daily living physical activities of rural pregnant women, across most continents in the world, involve adoption of high-flexion postures like deep-squat. Deep-squat elicits substantial activation of major trunk and lower extremity muscles. Adequate strength of trunk muscles is known to facilitate forward-downward propulsion of baby during labour. Therefore, current study aimed to explore influence of overall physical activity including squat exposure on trunk and lower-extremity muscle strength and labour outcomes in rural and urban primigravida women. Twenty-eight primi-gravida women were stratified into 2 groups: rural habitual-squatters (n=14) and urban non-squatters (n=14). Daily …

The Quantification Of Muscle Activation During The Loaded Carry Movement Pattern, Samuel H. Ellestad, Thomas P. Holcomb, Alexis M. Swiergol, Michael E. Holmstrup Phd, Jeremy R. Dicus

International Journal of Exercise Science

International Journal of Exercise Science 17(1): 480-490, 2024. The ‘loaded carry’ is a popular resistance training activity that activates core musculature across multiple movement planes while the body is in locomotion. ‘Hold’ exercises are similar to carry exercises but lack the locomotive aspect. Both carry and hold exercises can be completed bilaterally (farmer’s carry (FC) and hold (FH)) or unilaterally (suitcase carry (SC) and hold (SH)). A deeper understanding of muscle activation between the FC and SC and intensity-matched FH and SH might improve their application. Healthy, college-aged individuals were recruited and surface electromyography of the rectus abdominis (RA), external …

Recipe For Research Success: Mentorship & Organization, Kristen Montgomery

Epsilon Sigma at-Large Research Conference

Kristen S. Montgomery, PhD, CNM is an Assistant Professor at East Tennessee State University College of Nursing in Johnson City, TN. She received her PhD in Nursing from Case Western Reserve University in Cleveland, OH, her MSN in perinatal nursing from the University of Pennsylvania in Philadelphia, and her BSN from Oakland University in Rochester, Michigan. She received a post-master’s certificate in nurse-midwifery from East Carolina University and completed a Post-Doctoral Program in Health Promotion and Risk Reduction Interventions at the University of Michigan.

Cavernous Wonders: Delving Into Cavernous Sinus Syndrome In Neuro-Ophthalmology, Anza Rizvi, Ba

inSIGHT

Cavernous sinus syndrome (CSS) is any disease process that affects the cavernous sinus. This syndrome is marked by a complex interplay of neurovascular symptoms, primarily due to the compression or dysfunction of the cranial nerves that traverse the cavernous sinus. Understanding the intricate details of this syndrome is critical to providing optimal care and improving patient outcomes.

Seeing Clearly: A Bright Future With Light Adjustable Intraocular Lenses For Presbyopia, Shady Mina, Bs

inSIGHT

Presbyopia, or the age-related decline in the ability to focus on near objects, is a common vision disorder that affects 1.8 billion people globally, with this number expected to increase to 2.1 billion by 2030.^1-4 A diminished accommodation response is the primary cause of presbyopia.¹ The eye has a very complex accommodation mechanism that permits people to distinctly see objects from various distances.^1,3 Even though the precise mechanism of accommodation is yet to be determined, the current evidence strongly supports Helmholtz’s theory, which claims that the thickness and curvature of the eye’s lens increase while its diameter …

Medical Missions, Ethical Considerations And The Future For Healthcare Delivery In Ophthalmology, Robert Medina, Ba

inSIGHT

Beginning hundreds of years ago, priests from Europe embarked on ‘medical missions’ with the goals of delivering care to the body, mind, and soul. Hundreds of years later, members of the United States healthcare system set out on humanitarian medical missions to provide medical assistance to communities in developing countries.¹ The concept of providing care internationally as a product of global social responsibility has become engrained in the United States healthcare system, and is popular among providers, trainees, and pre-medical students. In 2023, 21.8% (n = 3264) of matriculating medical students reported participating in international volunteer work, while 7.0% …

Chronic Progressive External Ophthalmoplegia, Bahram Pashaee, Mph, Bs

inSIGHT

Chronic progressive external ophthalmoplegia is an inherited or sporadic form of dystrophy that preferentially affects the extraocular muscles of the eye. While this dystrophy can manifest systemically, the extraocular muscles are commonly involved due to their constant metabolic demands and vulnerability to oxidative stress.¹ This preferential involvement of the eyelid levator muscle and extraocular muscles makes CPEO an important condition to consider in a differential diagnosis for eyelid asymmetry and double vision among other conditions such as myasthenia gravis, thyroid-associated ophthalmoplegia, and other mitochondrial myopathies.² This dystrophy tends to occur in the third or fourth decade of life. …

Macular Holes: Diagnosis, Treatment, And Complications, Ayra Khan, Bs

inSIGHT

Macular hole is a condition that affects the central visual field of the eye. Without prompt diagnosis and intervention, macular holes can progressively worsen, significantly impacting both vision and overall quality of life.

Cmv Retinitis: An Expert’S Perspective, Caitlyn Kwun, Ba

inSIGHT

Uveitis is a rare inflammatory disease with a prevalence of around 38 per 100,000 people and is the overall 5th leading cause of blindness in the developed world.^1,2 Uveitis is most commonly found in patients younger than 40 years of age, but it can occur in any age group with an etiology that varies within each age demographic.^1,3 While the etiology of certain forms of uveitis are not fully understood, there are some that are autoimmune in nature and others that are associated with systemic diseases such as sarcoidosis.⁴ Uveitis may be inflammatory or infectious. It may …

Bridging The Global Gap Of Blindness Through Artificial Intelligence - Exploring The Tools Of Ai To Address The Top Causes Of Blindness In Under-Resourced Communities Worldwide, Nathan Delacth, Bs

inSIGHT

Technological advancements have allowed us to submerge in a sea of innovation and excellence in medicine. Electronic health records transformed the healthcare landscape, improving portability of patient information while streamlining communication and fostering collaboration.¹ Imaging technologies, such as magnetic resonance imaging (MRI) and Optical computed tomography (OCT), granted us the ability to view internal structures using non-invasive methods. In a similar vein, artificial intelligence (AI) has emerged as an impactful force in various fields of medicine, and its influence on ophthalmology is no exception.

Evolution Of Lamellar Keratoplasty, Ishan Kasat, Bs

inSIGHT

Overview of Keratoplasty The evolution of corneal transplantation, or keratoplasty, has seen a paradigm shift from traditional penetrating keratoplasty (PKP) to the refined precision of lamellar keratoplasty (LK). Penetrating, or full thickness, keratoplasty is a replacement of all corneal layers: epithelium, Bowman's layer, stroma, Descemet's membrane, and endothelium.¹ Lamellar, or partial thickness, keratoplasty involves replacement of either epithelium and stroma (anterior lamellar) or Descemet’s membrane and endothelium (posterior lamellar).² From 1985 to 2004, over 95% of graft tissues were used for PKP. However, from 2005 to 2014, the percentage of PKP procedures decreased from 95% to 42%, while …

The Myopia Epidemic: Exploring The Pathology And Management Of The World’S Most Common Eye Disorder, Gabriella Baldassarre, Bs

inSIGHT

Myopia is the most common eye disorder in the world and an increasing cause of vision impairment in children.¹ Myopia is an imbalance in the refractive components of the eye and its length, leading to inaccurate focusing of light rays in front of the retina tissue instead of on it. There is a spectrum of severity of myopia, from mild nearsightedness to a more severe form known as high or degenerative myopia, which has the potential to cause vision loss and blindness. There is evidence of a developing myopia epidemic, with an estimated one-third of the world population affected …

Insight, Volume 4, Issue 1, 2024

inSIGHT

Contents

8 - The Myopia Epidemic: Exploring the Pathology and Management of the World’s Most Common Eye Disorder
By Gabriella Baldassare

15 - Evolution of Lamellar Keratoplasty
By Ishan Kasat

19 - Bridging the Global Gap of Blindness Through Artificial Intelligence
By Nathan Delacth

24 - CMV Retinitis: An Expert’s Perspective
By Caitlyn Kwun

29 - Macular Holes: Diagnosis, Treatment, and Complications
By Ayra Khan

36 - Chronic Progressive External Ophthalmoplegia
By Bahram Pashaee

39 - Medical Missions, Ethical Considerations, and the Future for Healthcare Delivery in Ophthalmology
By Robert Medina

43 - Shaping the Future of Vision: The Rise …

Tension Activation Of Mechanosensitive Two-Pore Domain K+ Channels Traak, Trek-1, And Trek-2., Ben Sorum, Trevor Docter, Vincent Panico, Robert A Rietmeijer, Stephen G Brohawn

Cooper Medical School of Rowan University Departmental Research

TRAAK, TREK-1, and TREK-2 are mechanosensitive two-pore domain K+ (K2P) channels that contribute to action potential propagation, sensory transduction, and muscle contraction. While structural and functional studies have led to models that explain their mechanosensitivity, we lack a quantitative understanding of channel activation by membrane tension. Here, we define the tension response of mechanosensitive K2Ps using patch-clamp recording and imaging. All are low-threshold mechanosensitive channels (T10%/50% 0.6-2.7 / 4.4-6.4 mN/m) with distinct response profiles. TRAAK is most sensitive, TREK-1 intermediate, and TREK-2 least sensitive. TRAAK and TREK-1 are activated broadly over a range encompassing nearly all physiologically relevant …

Medical School Watercooler Newsletter - April 11, 2024, Lindsey Lyle

Watercooler Newsletter

This is the April 11, 2024 edition of the Frederick P. Whiddon College of Medicine’s newsletter - Watercooler.

Contents Include

• Fleck inaugurated as first female president of AUA's Southeastern Section
• Faculty and staff pilot pre-course meeting to improve student learning
• Menger named to Becker’s National Emerging Leaders in Healthcare list
• Obiaka appointed director of Pediatric Echocardiography Lab
• USA to raise sickle cell disease awareness at ArtWalk
• Participants complete Medical Education Research Certificate Program
• Pathology faculty and residents present at USCAP annual meeting
• OB/GYN Interest Group hosts annual feminine hygiene products donation drive

Poster Abstracts For 14th Annual University Of Dayton And Miami Valley Hospital Healthcare Symposium, Udayton

Pre-Health Resource Center Campus Communications

No abstract provided.

Spartan Daily, April 11, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 162, Issue 31

Enhancing Srna Confidence: Simulation-Based Crm Training For The Management Of Intraoperative Cardiac Arrest, Melissa Lee

Doctor of Nursing Practice Scholarly Projects

Intraoperative emergencies in the operating room (OR) are rare but necessitate early recognition and intervention.

Conquer And Prevail Issue 161 April 11 2024, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.

The Indiana Statesman, April 11, 2024, Indiana State University

Student Newspaper

Student small business market; President releases statement on racist video; Indiana will continue to see severe weather

Program Development For Adults And School-Aged Children With Down Syndrome At Gigi’S Playhouse, Jenna Rae Luna

OTD Capstone Projects

This doctoral capstone project was completed through partnership with GiGi’s Playhouse - Nashville, a non-profit organization offering free programming and services to individuals of all ages with Down syndrome and their families. The focus of this project was to develop and implement programming for GiGi Achievers, an adult education program, in the areas of money management, physical health and wellness, cooking, communication, and daily life skills. The results were physical and digital materials to be used for future adult education programming modified to address participant and caregiver feedback. A curriculum for GiGi Achievers was also developed as a guideline for …

Exploring The Implications: The Impact Of Universal Design For Learning On Student Engagement And Motivation In Diverse Classroom Environments, Hilary Sanguinetti

Doctor of Education (EdD)

This improvement science dissertation in practice (ISDiP) investigated the influence of universal design for learning (UDL) on student engagement and motivation in middle school classrooms at a K–8 school in Northern California. The plan-do-study-act (PDSA) framework examined the potential of UDL practices in the context of a Diocesan-wide professional development initiative and assessed if teachers’ deliberate integrations of UDL strategies contributed to enhanced student engagement and motivation. The study navigated nuances of transitions to UDL practices, observing teachers as they attempted to implement strategies while students participated in UDL lessons. This process uncovered intrinsic challenges educators face—adherence to traditional teaching …

Examining Adverse Childhood Experiences And Black Youth's Engagement In A Hospital-Based Violence Intervention Program Using Administrative Data, Laura A. Voith, Amy Korsh-Williams

Faculty Scholarship

Background: Stemming from poverty and systemic racism, Black youth are disproportionately represented in hospital-based violence intervention programs (HVIPs) due to greater violence exposure. HVIPs are a critical intervention that have been shown to reduce rates of reinjury in urban hospitals and trauma centers across the United States; however, they are plagued by low enrollment and engagement rates. Few studies have examined factors related to engagement, particularly among Black youth. Methods: Guided by Trauma Theory and Critical Race Theory, this study uses a retrospective cohort design. Between-group differences of adverse childhood experiences (ACEs) among engaged youth compared to nonengaged youth who …

Vista: April 11, 2024, University Of San Diego

USD Vista (1965-)

No abstract provided.

Individual Differences In Cannabis Use Disorder With Implications For Endocannabinoid Modulation In Therapeutics Development, Erin L. Martin

MUSC Theses and Dissertations

Cannabis use disorder (CUD) is increasingly prevalent in the United States, but there is no effective pharmacological means to treat it. The endocannabinoid (eCB) system has emerged as a candidate therapeutic target demonstrating some evidence of efficacy in treating CUD. However, clinical trials evaluating eCB-modulating therapeutics have historically undervalued individual differences that could contribute to variation in treatment outcome (e.g. sex, comorbid psychiatric illness). To address this gap in the literature, the present set of studies (a) compared plasma eCB tone in groups underrepresented in treatment trials for CUD (females, individuals with comorbid major depressive disorder; MDD/CUD) with males or …

2024 April 11 - Academic Council Agenda And Minutes, Academic Council, East Tennessee State University

Academic Council Agenda and Minutes

No abstract provided.

Baccalaureate Nurses' Experiences And Understanding Of Adults Living With Sickle Cell Disease, Shelia A. Reid

Dissertations

Background: Sickle cell disease (SCD) is a chronic, genetic blood disorder with most treatment interventions geared toward the acute phase of the disease, which often leads to fragmented care. In Canada, the teaching of SCD occurs without a genetic competency, resulting in miscommunication, misunderstanding, and inadequate nursing care.

Purpose: This investigator examined baccalaureate nurses' experiences and understanding of working with adults living with SCD.

Methods: A semi-structured interview guide was used to explore baccalaureate nurses' experiences and understanding of working with young adults living with SCD.

Results: Lindseth and Norbergs' (2004) interpretation of Ricoeur's hermeneutic interpretative phenomenological approach was used …

Organizational Agents As Epistemic Agents: Re-Examining Nurse Executives' Agency In Homecare Organizations, Lisa Ashley

Dissertations

This research presents a critical analysis and original theoretical approach to a complex phenomenon that addresses current gaps in our understanding of the experiences of nurse executives and their organizational positioning in homecare organizations. It reveals how nurse executives experience paradoxical identities of executive and nurse. The competitiveness of homecare as a business and the status of homecare among other healthcare sectors is problematic and exacerbates the tension between those two identities. This qualitative research aims to explore NEs' epistemic and discursive organizational positioning in HCOs. This research also explores how nurse executives enact their moral, socio-professional, political and epistemic …

The Lived Experiences Of Student Nurses During Simulation Of Perinatal Loss, Paloma Alejandra Peña

Dissertations

The purpose of this phenomenological study was to understand the experiences and perceptions of undergraduate nursing students in providing care following a perinatal loss simulation. The theories that guided this study included Malcolm Knowles' Theory of Andragogy and the National League for Nursing Jeffries Simulation. The selected theories provide structure for adult learners' need to experience situational learning activities that are relevant to their job while building upon the foundation of students' knowledge. Incorporation of Knowles' and Jeffries' theories guides the qualitative study of the simulation of a perinatal loss and the experiences of nursing students in providing care during …