Digital Commons Network^™

Exploring The Role Of Intrinsic Motivation In Elementary Public-School Educators’ Willingness To Remain In Teaching, Lynnette K. Steinhoff

Walden Dissertations and Doctoral Studies

The experiences and perceptions of novice educators’ willingness to remain in teaching have been without clear research. The problem addressed by this study was the need to understand why novice educators remain in the field in order to support districts and legislators in updating policies and funding measures. The purpose of this qualitative study was to explore how the intrinsic motivation of novice elementary educators within a K–12 public school influences their willingness to remain in teaching. Self-determination theory (SDT), with its psychological principles of autonomy, competency, and relatedness, was selected as the conceptual framework. Two research questions addressed intrinsic …

Healthcare Experiences Of Transgender Adults Who Are African American, Lacole Cole

Walden Dissertations and Doctoral Studies

African Americans struggle to access healthcare because of a combination of overt racism, implicit bias from providers, and the effects of systemic racism. As a result, researchers have studied the challenges of this specific adult population. Less research has been centered on those individuals who are both African American and transgender. The purpose of this generic qualitative study was to explore the experiences of this population. Guided by intersectionality theory, the study’s research question asked about the experiences of African American transgender adults and their efforts to obtain necessary healthcare services to manage optimal health. Semi-structured interviews were conducted with …

Family Medicine’S Role In Addressing The Intersections Of Redlining And Climate Change, Daryl O. Traylor, Eboni E. Anderson, Brianna Clark, Alex M. Smith, Cooper K. Allenbrand

Journal of Sustainable Social Impact

Redlining, the practice of discriminating against specific neighborhoods based on race and socioeconomic status, leads to persistent environmental hazards and socioeconomic inequalities that have lasting adverse health effects on their populations. Health disparities are further exacerbated through the concentration of environmental hazards, as well as the escalating impact of climate change, which poses an increased risk of respiratory illness, cardiovascular disease, mental health issues, heat-related illness, infectious diseases, food insecurity, and socioeconomic difficulties in redline neighborhoods.

This paper examines the interplay of redlining, climate change, and health disparities, with an emphasis on the enduring consequences for these marginalized communities. Through …

Designing, Implementing And Testing An Intervention Of Affective Intelligent Agents In Nursing Virtual Reality Teaching Simulations—A Qualitative Study, Michael Loizou, Sylvester Arnab, Petros Lameras, Thomas Hartley, Fernando Loizides, Praveen Kumar, Dana Sumilo

School of Nursing and Midwifery

Emotions play an important role in human-computer interaction, but there is limited research on affective and emotional virtual agent design in the area of teaching simulations for healthcare provision. The purpose of this work is twofold: firstly, to describe the process for designing affective intelligent agents that are engaged in automated communications such as person to computer conversations, and secondly to test a bespoke prototype digital intervention which implements such agents. The presented study tests two distinct virtual learning environments, one of which was enhanced with affective virtual patients, with nine 3rd year nursing students specialising in mental health, during …

Relations Between Prior Racial Microaggressions, Expat Motivation, And Life Satisfaction Among African American Expat Women In Mexico, Patricia Keller

Dissertations

Microaggressions refer to subtle forms of racism that occur in everyday interactions, often conveying hostile or demeaning messages. These experiences can have a negative impact on the psychological well-being and life satisfaction of African Americans. However, there is a lack of research that explores the relationship between microaggressions and the life satisfaction of African American women who have relocated abroad. Additionally, little is known of the contemporary motivations for expatriation of African American women. A review of African American historical migration, study abroad participation, and tourism lays the framework for examining recent expatriation. The purpose of this study was to …

Improving Oral Health And Related Health Behaviours (Substance Use, Smoking, Diet) In People With Severe And Multiple Disadvantage: A Systematic Review Of Effectiveness And Cost-Effectiveness Of Interventions, Laura J. Mcgowan, Deepti A. John, Ryan P.W. Kenny, Emma C. Joyes, Emma A. Adams, Hosein Shabaninejad, Catherine Richmond, Fiona R. Beyer, David Landes, Richard G. Watt, Falko F. Sniehotta, Martha Paisi, Claire Bambra, Dawn Craig, Eileen Kaner, Sheena E. Ramsay

Peninsula Dental School

Background: People experiencing homelessness co-occurring with substance use or offending (‘severe and multiple disadvantage’ SMD) often have high levels of poor oral health and related health behaviours (particularly, substance use, smoking, poor diet). This systematic review aimed to assess the effectiveness and cost-effectiveness of interventions in adults experiencing SMD to improve oral health and related health behaviours. Methods and findings: From inception to February 2023, five bibliographic databases (MEDLINE, EMBASE, PsycINFO, CINAHL, and Scopus) and grey literature were searched. Two researchers independently screened the search results. Randomized controlled trials (RCTs), comparative studies and economic evaluations were included that reported outcomes …

The Grizzly, April 18, 2024, Marie Sykes, Nicolas Ungurean, Andrew J. Perez, Ellie Burns, Kathy Logan, Kate Horan, Sidney Belleroche, Renee Washart, James Rapp

Ursinus College Grizzly Newspaper, 1978 to Present

Tensions High at Congressional Town Hall • Tree Planting Ceremony to Honor Damiano Rotolo • Ursinus Hosting "Out of Darkness" Walk • Phi Kap's LLS Fundraiser • Expert Tips on Graduate School Planning: What You Need to Know • First Year Review on First-Year Housing • Every REP Matters • ReLAXing is Not an Option

Chapter 11: Treatment Of Detained Persons

International Law Studies

The Commander’s Handbook on the Law of Naval Operations is used in the United States and throughout the world as a restatement of U.S. doctrinal law positions on matters affecting the operations of the U.S. Navy, the U.S. Marine Corps, and the U.S. Coast Guard. Judge advocates and legal advisers have occasion to conduct deeper research to identify the context and source of the rules reflected in the Commander’s Handbook. Responding to this need, an Annotated Supplement to The Commander’s Handbook was produced in 1997 and published as volume 73 of International Law Studies. In the intervening decades, …

Diagnosis And Current Treatment Strategies For Adult And Juvenile Hereditary Hemochromatosis, Tori Tyler, Amber Wiggins-Mcdaniel, Staton Mcbroom, Caroline Parry, Robert Tyler, Robert A. White

Student Publications

Hemochromatosis is a common genetic disorder manifesting as an iron overload state requiring complex processes in diagnosis, treatment, and management of both adult, and pediatric, populations. This review outlines general diagnostic and treatment strategies for hemochromatosis detailing fundamental processes in iron excess, or iron overload, through physiologic function and associated pathological effects. Genetic mutations, as ascribed to hemochromatosis, have significant impact in producing pathophysiology. Understanding basic pathophysiological mechanisms can inform future diagnosis and treatment through advances such as erythrocytophoresis. Linking concepts related to the diagnosis, treatment, and management of adult and juvenile hereditary hemochromatosis with scientific advances may enlighten clinical …

Montana Kaimin, April 18, 2024, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Fourteen-Day Vonoprazan-Based Bismuth Quadruple Therapy For H Pylori Eradication In An Area With High Clarithromycin And Levofloxacin Resistance: A Prospective Randomized Study (Vq-Hp Trial), Sith Siramolpiwat, Thanee Eiamsitrakoon, Pornpen Gamnarai, Arti Wongcha-Um, Yoshio Yamaoka, Kammal Kumar Pawa, Ratha-Korn Vilaichone

Faculty, Staff and Students Publications

Potassium-competitive acid blockers (P-CABs) provide potent acid inhibition, yet studies on P-CAB-based quadruple therapy for H. pylori eradication are limited. We theorized that integrating bismuth subsalicylate into a quadruple therapy regimen could enhance eradication rates. However, data on the efficacy of vonoprazan bismuth quadruple therapy are notably scarce. Therefore, the aim of this study was to evaluate the efficacy of vonoprazan-based bismuth quadruple therapy in areas with high clarithromycin and levofloxacin resistance. This was a prospective, single-center, randomized trial conducted to compare the efficacy of 7-day and 14-day vonoprazan-based bismuth quadruple therapy for H. pylori eradication between June 1, 2021, …

Somatic Mutations Of Esophageal Adenocarcinoma: A Comparison Between Black And White Patients, Jinyoung Byun, Patricia D Castro, Spiridon Tsavachidis, Jianhong Hu, Harshavardhan Doddapaneni, Yi Han, Donna M Muzny, Richard A Gibbs, Christopher I Amos, Aaron P Thrift

Faculty, Staff and Students Publications

Esophageal adenocarcinoma is the most common histological subtype of esophageal cancer in Western countries and shows poor prognosis with rapid growth. EAC is characterized by a strong male predominance and racial disparity. EAC is up to fivefold more common among Whites than Blacks, yet Black patients with EAC have poorer survival rates. The racial disparity remains largely unknown, and there is limited knowledge of mutations in EAC regarding racial disparities. We used whole-exome sequencing to show somatic mutation profiles derived from tumor samples from 18 EAC male patients. We identified three molecular subgroups based on the pre-defined esophageal cancer-specific mutational …

Perspectives From Patients With Chronic Lung Disease On A Telehealth-Facilitated Integrated Palliative Care Model: A Qualitative Content Analysis Study, Jeannette Kates, Carrie Tompkins Stricker, Kristin L. Rising, Alexzandra Gentsch, Ellen Solomon, Victoria Powers, Venise J. Salcedo, Brooke Worster

Department of Medicine Faculty Papers

BACKGROUND: Chronic lung disease affects nearly 37 million Americans and often results in significant quality of life impairment and healthcare burden. Despite guidelines calling for palliative care (PC) integration into pulmonary care as a vital part of chronic lung disease management, existing PC models have limited access and lack scalability. Use of telehealth to provide PC offers a potential solution to these barriers. This study explored perceptions of patients with chronic lung disease regarding a telehealth integrated palliative care (TIPC) model, with plans to use findings to inform development of an intervention protocol for future testing.

METHODS: For this qualitative …

Cdk8/Cdk19 Promotes Mitochondrial Fission Through Drp1 Phosphorylation And Can Phenotypically Suppress Pink1 Deficiency In Drosophila, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C Marcogliese, Katherine Sew, Hugo J Bellen, Esther M Verheyen

Faculty, Staff and Students Publications

Cdk8 in Drosophila is the orthologue of vertebrate CDK8 and CDK19. These proteins have been shown to modulate transcriptional control by RNA polymerase II. We found that neuronal loss of Cdk8 severely reduces fly lifespan and causes bang sensitivity. Remarkably, these defects can be rescued by expression of human CDK19, found in the cytoplasm of neurons, suggesting a non-nuclear function of CDK19/Cdk8. Here we show that Cdk8 plays a critical role in the cytoplasm, with its loss causing elongated mitochondria in both muscles and neurons. We find that endogenous GFP-tagged Cdk8 can be found in both the cytoplasm and nucleus. …

April 18, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Predictors Of Sinonasal Improvement After Highly Effective Modulator Therapy In Adults With Cystic Fibrosis, Daniel M. Beswick, Christine M. Liu, Jonathan B. Overdevest, Anna Zemke, Aastha Khatiwada, David A. Gudis, Jessa E. Miller, Adam Kimple, Jeremy P. Tervo, Todd E. Bodner, Multiple Additional Authors

Psychology Faculty Publications and Presentations

The 22-question SinoNasal Outcome Test (SNOT-22) assesses chronic rhinosinusitis (CRS) severity. We aimed to identify predictors of SNOT-22 score improvement following highly effective modulator therapy (HEMT) initiation and to corroborate the SNOT-22 minimal clinically important difference (MCID) in adults with cystic fibrosis (CF).

Criminal Protection Of Privacy And Data Security In Smart Cities - A Comparative Study, Dr. Emadeldin Mohamed Kammel Abdulhamed

Faculty Peer-Reviewed Papers | بحوث هيئة التدريس المحكمة

A huge wealth of data flows through the vocabulary of the digital world, especially the facilities and institutions of smart and electronic state governments, with the multiplicity, diversity and development of the technologies for collecting, processing, analyzing and converting it, and the development of the technologies of cyber attacks on it, which resulted in a real crisis related to the violation of privacy and the breach of data security, for individuals, companies and smart and electronic state governments. The subject of the study, which is the criminal protection of privacy and data security in smart cities, aims to achieve the …

The Association Of Prenatal Fine Particulate Matter (Pm2.5) Airway Exposure And Pulmonary Function Among Preschool Children: The Mediation Effect Of Dna Methylation At Birth And Metabolites, Nutrients, And Toxins In Cord Blood, Rui Luo

Electronic Theses and Dissertations Archive

Prenatal exposure to particulate matter with an aerodynamic diameter of less than 2.5 µm (PM2.5) has been linked to altered lung function and respiratory diseases. However, the conclusions of previous studies are controversial. To our knowledge, no study examined whether DNA methylation (DNAm), metabolites, nutrients, and toxins (MNTs) at birth mediate the association between prenatal PM2.5 exposure with multiple respiratory outcomes. This dissertation includes three carefully designed studies focusing on prenatal PM2.5 exposure, and its association with respiratory outcomes. Data obtained from three generation of Isle of Wight birth cohort (IOWBC) were utilized. In the first study, I examined the …

Assessing Design Quality In Online Courses At A Public University, Anthony Kiech

Electronic Theses and Dissertations Archive

This research assesses the extent to which asynchronous online STEM courses at a public university integrate Merrill's First Principles of Instruction. Through a quantitative content analysis of thirty unique online courses within the College of Arts and Sciences, the study investigates the extent, if any, to which these courses embody principles such as problem-centered learning, activation, demonstration, application, and integration. A validated survey instrument, Course Scan, was used for evaluation and indicated a low extent of Merrill's First Principles of Instruction in the sample courses. Methodology, including the investigation plan and instrumentation, are shared. Results are shared, indicating low implementation …

Parp-Ish: Gaps In Molecular Understanding And Clinical Trials Targeting Parp Exacerbate Racial Disparities In Prostate Cancer, Moriah L. Cunningham, Matthew J. Schiewer

Department of Urology Faculty Papers

PARP is a nuclear enzyme with a major function in the DNA damage response. PARP inhibitors (PARPi) have been developed for treating tumors harboring homologous recombination repair (HRR) defects that lead to a dependency on PARP. There are currently three PARPi approved for use in advanced prostate cancer (PCa), and several others are in clinical trials for this disease. Recent clinical trial results have reported differential efficacy based on the specific PARPi utilized as well as patient race. There is a racial disparity in PCa, where African American (AA) males are twice as likely to develop and die from the …

Teachers’ Perceptions Of Reading Comprehension Among Fifth-Grade Students With Exceptionalities As A Result Of The Pandemic, Paula Webb

Walden Dissertations and Doctoral Studies

The problem addressed through this study is the low reading comprehension levels of fifth-grade students with exceptionalities (SwE) (e.g. dyslexia) in a local school district in Georgia. The purpose of this qualitative study was to explore fifth-grade teachers’ perceptions on their successes, challenges, and suggestions when teaching reading to SwE. The conceptual frameworks were the blended learning model and the constructivism model. The methodology of this research study was a basic qualitative design. Data were collected through semistructured interviews with eight fifth-grade teachers in a large school district in Georgia to investigate the reading foundational skills SwE are lacking that …

Human Dna Polymerase Θ Does Not Harbor Intrinsic Nuclease Activity, Denisse Carvajal-Maldonado, Karl Zahn, Ryan Jensen, Richard D Wood, Sylvie Doublié

Faculty, Staff and Student Publications

No abstract provided.

Antiviral Cellular Therapy For Enhancing T-Cell Reconstitution Before Or After Hematopoietic Stem Cell Transplantation (Aces): A Two-Arm, Open Label Phase Ii Interventional Trial Of Pediatric Patients With Risk Factor Assessment., Michael D. Keller, Patrick J. Hanley, Yueh-Yun Chi, Paibel Aguayo-Hiraldo, Christopher C. Dvorak, Michael R. Verneris, Donald B. Kohn, Sung-Yun Pai, Blachy J. Dávila Saldaña, Benjamin Hanisch, Troy C. Quigg, Roberta H. Adams, Ann Dahlberg, Shanmuganathan Chandrakasan, Hasibul Hasan, Jemily Malvar, Mariah A. Jensen-Wachspress, Christopher A. Lazarski, Gelina Sani, John M. Idso, Haili Lang, Pamela Chansky, Chase D. Mccann, Jay Tanna, Allistair A. Abraham, Jennifer L. Webb, Abeer Shibli, Amy K. Keating, Prakash Satwani, Pawel Muranski, Erin Hall, Michael J. Eckrich, Evan Shereck, Holly Miller, Ewelina Mamcarz, Rajni Agarwal, Satiro N. De Oliveira, Mark T. Vander Lugt, Christen L. Ebens, Victor M. Aquino, Jeffrey J. Bednarski, Julia Chu, Suhag Parikh, Jennifer Whangbo, Michail Lionakis, Elias T. Zambidis, Elizabeth Gourdine, Catherine M. Bollard, Michael A. Pulsipher

Manuscripts, Articles, Book Chapters and Other Papers

Viral infections remain a major risk in immunocompromised pediatric patients, and virus-specific T cell (VST) therapy has been successful for treatment of refractory viral infections in prior studies. We performed a phase II multicenter study (NCT03475212) for the treatment of pediatric patients with inborn errors of immunity and/or post allogeneic hematopoietic stem cell transplant with refractory viral infections using partially-HLA matched VSTs targeting cytomegalovirus, Epstein-Barr virus, or adenovirus. Primary endpoints were feasibility, safety, and clinical responses (>1 log reduction in viremia at 28 days). Secondary endpoints were reconstitution of antiviral immunity and persistence of the infused VSTs. Suitable VST …

Burnout Symptoms Among Millennial Teachers In India: The Efficacy Of The Emotional Self-Care Online Intervention Program (Escoip), Joby Thomas, Marc Eric S. Reyes

Makara Human Behavior Studies in Asia

The experiences of millennial teachers—currently comprising the majority of the teaching workforce—have gained attention in scholarly research. The phenomenon of teacher burnout, in particular, has gained greater attention in recent years due to its grave impact on the educational system and the well-being of teachers. Thus, developing an effective online intervention program is crucial to alleviate and avoid burnout among millennial teachers. Using Conklin’s program development model, which involves three phases, (1) planning, (2) design and implementation, and (3) evaluation and program validation, this study investigated the effectiveness of the Emotional Self-Care Online Intervention Program (ESCOIP) in treating burnout symptoms …

Social Health In Young Women With Chronic Pain, Ian A. Boggero, Linda Sangalli, Lauryn Brasch, Christopher D. King

Psychology Faculty Publications

Introduction:Chronic pain may negatively affect social functioning, but no study to date has examined the specific social impact of different chronic pain conditions in young women, and whether living with multiple chronic overlapping pain conditions (COPCs) differently influences social domains.Objectives:This study aimed to assess social functioning (social isolation, hostility, informational support satisfaction, social roles, emotional support, friendships, and family relationships) among young women with chronic pain compared with pain-free controls and to test whether the number of COPCs influenced the extent of social burden.Methods:Participants aged 18 to 30 years with a physician-confirmed diagnoses of migraine, fibromyalgia, or temporomandibular disorder (TMD) …

Analysis Of Self, Janna Gilbertson

Dissertations, Theses, and Projects

Abstract

Self-analysis is an opportunity to reflect, consult with others, research how the threads of our lives are woven into collective experiences, and to challenge our own patterns of thinking and behavior. My intention for this project is to illustrate how both my personal and professional life have evolved using self-reflection, tools such as the Myer Briggs Type Indicator and Strong Interest Inventory, and interviews with my friends and family. I discuss the impact that existential theory, feminist theory, and Vygotsky’s sociocultural theory of cognitive development have had on my past and why I desire to incorporate the principes of …

Mechanisms Of Rod Photoreceptor Metabolism And Function In Health And Disease, Tae Jun Lee

Arts & Sciences Graduate Student Theses and Dissertations

Over 250 million people globally live with visual acuity loss or blindness as an estimated 7 million people suffer from visual acuity loss in the United States. People in the United States value vision over memory, hearing, or speech and consider losing vision to be among the top four worst outcome to happen to them. The economic cost of major vision problems is estimated to increase to 373 billion dollars by the year 2050. Among the irreparable causes of vision loss, retinal degeneration stands as a chief contributor to catastrophic eye disease. The retina is a neurosensory tissue located in …

Germinal Center Persistence Diversifies B Cell Responses To Vaccination, Katherine Marie Mcintire

Arts & Sciences Graduate Student Theses and Dissertations

Vaccination is the best defense against infection, but highly variable and evolving pathogens like influenza virus pose a significant immunological challenge for vaccine design. An ideal influenza virus vaccine should elicit a durable and broadly cross-reactive antibody response. However, the development of cross-reactive antibodies is hindered by the high degree of antigenic variation among influenza viruses, particularly in the surface glycoprotein hemagglutinin (HA), which is the main target of vaccine-induced responses. Successful vaccination works by driving the differentiation of antigen-specific B cells into short-lived, antibody-secreting plasmablasts (PBs) and long-lived populations of memory B cells (MBCs) and bone marrow plasma cells …

Three Essays On Education Policy, Intergroup Relations, And Human Capital Accumulation, Wai Meng Jeremy Siow

Arts & Sciences Graduate Student Theses and Dissertations

The impact of education on fostering the development of human capital and molding sociopolitical attitudes from an early age is a well-explored topic in the field of social sciences. This dissertation takes a broader approach by delving into the consequences of two critical components of the education system: (1) the language used for instruction, and (2) citizenship education. To accomplish this, I employ a combination of observational and experimental research methods to disentangle the causal effects of these educational factors within the contexts of Malaysia and Singapore. Chapter 2 delves into the ramifications of adopting a non-native language of instruction …

Direct Hyperbilirubinemia And Infant Characteristics In A Newborn Intensive Care Population, Maritza Chavez, Holly Kastendieck, Jessie R. Maxwell, Dawn Novak

2024 Pediatric Research Forum Session

Background: Direct hyperbilirubinemia is frequently encountered in the NICU and is always a pathologic condition. It is exceedingly difficult to distinguish between common causes of direct hyperbilirubinemia based on laboratory work-up alone. Through retrospective chart review we aim to better establish the incidence of risk factors and progression of direct hyperbilirubinemia in the NICU, with the goal of streamlining the secondary evaluation.

Methods: A retrospective chart review was conducted for neonates admitted to the University of New Mexico Hospital NICU from February 1^st, 2019, through February 1^st, 2022 who had a direct hyperbilirubinemia level of .5 …