Digital Commons Network^™

Pbpa Creating Pathways To Ensure Patients Are Using Their Inhaled Medications Effectively, Suzan Michelle Collins, Heather Blake, Chandler Blodgett, Sue Vermette, Martine Eon

Operations Transformation

Problem: Patients do not consistently know how to prepare, use and/or clean their inhalers effectively.

Impact: When patients do not consistently know how to prepare, use and/or clean their inhalers effectively they are in fact, not receiving the benefit from their prescribed medication.

They experience poor patient outcomes and overall poor patient experience.

• Increased calls to provider offices for unresolved, worsening symptoms and/or complications. (Thrush, hoarseness, cardiac symptoms etc.)
• Increased same day office visits.
• Patient crowding in Urgent Care and/or Emergency Department.
• Hospital Admissions.
• Increase in emotional and financial stress from missing school and/or work.
• Increase in referrals to specialists …

Dynamic Changes In The Distribution Of Hydrocodone And Oxycodone In Florida From 2006 To 2021, Elena Lynn Stains, Akshay C. Patel, Jay P. Solgama, Joseph D. Hagedorn, Kenneth L. Mccall, Brian J. Piper

Pharmacy Faculty Scholarship

Background: Florida, which led the country in terms of its number of opioid-prescribing physicians, was unique during the height of the opioid epidemic because of its lax prescribing laws and high number of unregulated pain clinics. Here, we address differences in the distribution rates of oxycodone and hydrocodone across Florida counties during the peak years of the opioid epidemic using an under-utilized database. Methods: The Washington Post and the United States Drug Enforcement Administration’s Automation of Reports and Consolidated Orders System (ARCOS) databases provided longitudinal oxycodone and hydrocodone distribution data in grams per county (2006–2014) and state (2006–2021). Grams of …

Shattering The Mask: Unveiling The Destructive Force Of Misogynoir, Ledominique Hubbard

Dissertations

As a Black woman, my professional journey has been consistently marred by encounters with racism and gender bias. In this research, I employed autoethnography to shed light on my experiences and meticulously examine the challenges of misogynoir I faced while holding pivotal positions, including that of a detested team leader, an ingenious instructional teacher, and an anti-racist assistant principal across three distinct school campuses in two states. My narrative unfolds in various contexts, notably as the sole Black female teacher and team leader within nine elementary schools in a predominantly white, female-staffed rural district. Furthermore, I underscore my role as …

Discovering Potential In Non-Cancer Medications: A Promising Breakthrough For Multiple Myeloma Patients., Omar S Al-Odat, Emily Nelson, Tulin Budak-Alpdogan, Subash C. Jonnalagadda, Dhimant Desai, Manoj K Pandey

College of Science & Mathematics Departmental Research

Multiple myeloma (MM) is a common type of cancer that unfortunately leads to a significant number of deaths each year. The majority of the reported MM cases are detected in the advanced stages, posing significant challenges for treatment. Additionally, all MM patients eventually develop resistance or experience relapse; therefore, advances in treatment are needed. However, developing new anti-cancer drugs, especially for MM, requires significant financial investment and a lengthy development process. The study of drug repurposing involves exploring the potential of existing drugs for new therapeutic uses. This can significantly reduce both time and costs, which are typically a major …

Assessing The Effects Of Repetitive Mild Traumatic Brain Injury On Risk/Reward Decision Making And Catecholamine Associated Proteins, Christopher Knapp

Theses and Dissertations

Mild traumatic brain injury (mTBI) disrupts cognitive processes that influence risk taking behavior; however, the effects of repetitive mild injury (rmTBI) or whether these outcomes are sex specific are unknown. Risk/reward decision making is mediated by the prefrontal cortex (PFC), which is densely innervated by catecholaminergic fibers. Aberrant PFC catecholamine activity has been documented following TBI and may underlie TBI-induced risky behavior. Here, we exposed rats to sham (no injury), single, or three closed-head controlled cortical impact (CH-CCI) injuries to characterize the effects of rmTBI on 1) risk/reward decision making behavior using a probabilistic discounting task (PDT) and 2) levels …

Unsupervised Complex Condition Recognition Based On Stochastic Neighborhood Embedding, Lin Huang, Shanjun Liu, Wei Wang, Li Gong

Journal of System Simulation

Abstract: Modern industrial production equipment usually has a complex structure and runs alternately in different working conditions. Accurate working conditions identification based on monitoring data is the basis of health monitoring of the system, but the monitoring data of the system usually has a high dimension and a large data volume. To identify the complex equipment operating conditions, an unsupervised operating condition identification method based on stochastic neighborhood embedding is proposed. The stochastic neighborhood embedding algorithm can simultaneously preserve the local and global structural characteristics of the data, and also calculate the probability similarity of data points in high-dimensional and …

Black Men Who Participate In An Urban Community College Men Of Color Initiative: A Phenomenological Study, Steven Hardy

Theses and Dissertations

This phenomenological study explored the perceptions and experiences of Black men who participated in the MOCI. The study uncovered insights into what aspects of the program were effective and where improvements could be made according to the student participants. Employing a phenomenological design, the research identified commonalities among the participants' experiences (Creswell & Creswell, 2018; Moustakas, 1994; Rubin & Rubin, 2012). The structure of understanding surrounding participants in the MOCI program was meticulously facilitated using phenomenology (Creswell & Creswell, 2018). The interviews were not just semi-structured but also empathetic, with prepared open-ended questions followed by probing inquiries, all aimed at …

Advancing Influence In Social Networks Based On Game Theory, Adedamola Adesokan

Electrical and Computer Engineering ETDs

Online Social Networks (OSNs) have become part of our everyday life, as a means of interacting with people, sharing content, attending events, etc. Influencers are professional OSN users, who have a large loyal audience and use the OSNs to market various goods or services based on brand partnerships. In this thesis, we introduce a novel mechanism to enable OSN users to become influencers by strategically deciding their activity within the OSN. Initially, the concepts of social coordinates and social communities are proposed. Then, a non-cooperative game is introduced to enable the users to make optimal decisions regarding their activity in …

The Role Of Stakeholder Involvement In Enhancing Safe Drinking Water Infrastructure: An Interpretative Structural Modeling Approach, Awlya Rahmanea, Ayomi Dita Rarasati

CSID Journal of Infrastructure Development

One of the primary goals listed in the Sustainable Development Goals (SDGs) is to “Achieve universal and equitable access to safe and affordable drinking water for all,” as stated in SDG 6.1. To obtain this goal, the Government of Indonesia has developed the 2020-2024 National Medium-Term Development Plan (RPJMN), which has set specific targets including achieving 100% access to decent drinking water, 15% access to safe drinking water, and establishing 10 million house connections. The Ministry of National Development Planning has established a goal of achieving 45% access to safe drinking water by 2030 as part of the SDGs. However, …

Strategies For Resilient Build Back In The Post-Flood Era: An Ahp-Dematel Technique, Muhammad Tahir, Mohd Fadzil Bin Mohd Idris

CSID Journal of Infrastructure Development

Pakistan suffered from devastating floods in 2022, causing extensive infrastructural, economic, social, and other damages. Effective risk management was notably absent in the country. Therefore, this paper identifies critical factors influencing the build-back-better (BBB) framework and resilience building. The evaluation of various strategies for risk reduction in infrastructure during floods, ensuring its resilience, is also addressed. This study employs Multi-Criteria Decision Making (MCDM) techniques, specifically the Analytic Hierarchy Process (AHP) and the Decision-Making Trial and Evaluation Laboratory (DEMATEL), to assess critical factors in BBB in the context of devastating floods. The AHP analysis effectively ranked the identified factors based on …

Retracted: Empowerment Of Increasing Economic Resilience Post Covid-19 Janjang Wulung Village Community Through Creative Economic Village Planning, Alvian Wardhana, Muhammad Ramayuda, Faza Farhan Muhammad, Acyuta Putri Nariswari, Salsa Dwi Cahya, Garin Ardi Wicaksono, Dani Rizky Dianafi, Muhammad Ivan

CSID Journal of Infrastructure Development

This article has been retracted at the request of the authors.

Reason:

1. Conflict of interest for using an open database under the assignment of “Studio Desa” on the odd semester 2020/2021 at Perencanaan Wilayah dan Kota, Universitas Brawijaya

2. The plaintiff's consideration comes from another researcher under the assignment of “Studio Desa” related to the reconstruction of Journal results and development

3. Avoid bigger conflicts, especially those related to all parties, including authors, Plaintiff parties, institutions, and all parties involved

The Publisher

Hair Dye And Relaxer Use Among Cisgender Women In Embu And Nakuru Counties, Kenya: Associations With Perceived Risk Of Breast Cancer And Other Health Effects, Adana A. M. Llanos, Adiba Ashrafi, Teresa Olisa, Amber Rockson, Alexis Schaefer, Jasmine A. Mcdonald, Mary Beth Terry, Dede K. Teteh-Brooks, Dustin T. Duncan, Beatrice Irungu, Cecilia Kimani, Esther Matu

Health Sciences and Kinesiology Faculty Articles

Despite widespread use of hair products globally, little is known about the prevalence and patterns of use in populations outside the United States. As some hair products contain endocrine-disrupting chemicals (EDCs) and EDCs have been linked to breast cancer, which is increasing globally, in this study, we addressed key knowledge gaps about hair product use and practices, and perceptions of use among women in two counties in Kenya. Using community-engaged approaches in Embu and Nakuru, Kenya, we recruited women aged 15–50 years to complete a questionnaire that ascertained hair product use in the last 7–14 days, ever using hair dyes …

Neural Circuits Expressing The Serotonin 2c Receptor Regulate Memory In Mice And Humans, Hesong Liu, Yang He, Hailan Liu, Bas Brouwers, Na Yin, Katherine Lawler, Julia M. Keogh, Elana Henning, Dong Kee Lee, Meng Yu, Longlong Tu, Nan Zhang, Kristine M. Conde, Junying Han, Zili Yan, Nikolas A. Scarcelli, Lan Liao, Jianming Xu, Qingchun Tong, Hui Zheng, Zheng Sun, Yongjie Yang, Chunmei Wang, Yanlin He, I. Sadaf Farooqi, Yong Xu

Division of Basic Science Faculty Publications

Declined memory is a hallmark of Alzheimer’s disease (AD). Experiments in rodents and human postmortem studies suggest that serotonin (5-hydroxytryptamine, 5-HT) plays a role in memory, but the underlying mechanisms are unknown. Here, we investigate the role of 5-HT 2C receptor (5-HT2CR) in regulating memory. Transgenic mice expressing a humanized HTR2C mutation exhibit impaired plasticity of hippocampal ventral CA1 (vCA1) neurons and reduced memory. Further, 5-HT neurons project to and synapse onto vCA1 neurons. Disruption of 5-HT synthesis in vCA1-projecting neurons or deletion of 5-HT2CRs in the vCA1 impairs neural plasticity and memory. We show that a selective 5-HT2CR agonist, …

Analyzing The Effect Of The Construction Safety Audit Model Using The Business Process Model And Notation (Bpmn) Method On Improving Communication And Collaboration Between Stakeholders., Muhammad Ghazali, Danang Budi Nugroho, Yusuf Latief

CSID Journal of Infrastructure Development

The significant increase in infrastructure development is directly proportional to the rising accident rate in the construction sector, making it one of the highest-risk sectors for accidents. This phenomenon indicates that existing construction safety audits have not been effective in preventing accidents, largely because audits are generally conducted only at the construction stage. Audits at the design stage, however, have the potential to impact accident prevention significantly. Therefore, this research aims to develop a construction safety audit model using the Business Process Model and Notation (BPMN) and analyzes the impacts on stakeholder communication and collaboration. BPMN was chosen because it …

Investigating The Relationship Among The Construction Safety Plan, Knowledge Management, Audit Process, Information System, Web, And Bim With Construction Safety Performance, Zafira Alysha Fadli, Yusuf Latief, Danang Budi Nugroho

CSID Journal of Infrastructure Development

The rapid growth of high-rise building construction in Indonesia has led to a significant increase in accidents, necessitating a robust audit process for construction safety. This research investigates the relationship between construction safety plans (CSPs), audit processes, knowledge management (KM), information systems, the web, and BIM on construction safety performance, aiming to develop a BIM-based KM audit process. To analyze the significance level of various indicators for each variable considerable importance, a mixed-methods approach was employed, combining qualitative insights from expert interviews with quantitative analysis using Structural Equation Modeling (SEM) via SmartPLS. The findings in the study reveal that the …

The Lived Experience Of Stigmatization Due To Chemotherapy-Induced Hair Loss For Young Women With Cancer Who Attend College, Challna Blair

Walden Dissertations and Doctoral Studies

This study investigated the stigmatization experienced by young women in college due to chemotherapy-induced hair loss. Previous research primarily focused on older women, adolescents, and men, leaving a gap in understanding the impact on young college-age women. Using Goffman’s theory of stigma and Giorgi’s descriptive phenomenological method, six young women were interviewed confidentially. The primary research question asked what is the experience of stigma in young women in college who have hair loss during or following chemotherapy cancer treatment? The study revealed that these women often faced being ostracized by peers, received minimal family support, and experienced distressing scrutiny from …

June 28, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Manufacturing Of Aligned Electrospun Nanofiber Yarns For Their Enhanced Mechanical And Piezoelectric Properties, Adaugo Mary-Frances Enuka

Theses and Dissertations

Electrospinning is a widely used technique for producing nanofibers with diverse applications. This method uses polymer solutions and strong electric fields to generate nano-sized fibers with unique properties. This study presents a novel manufacturing approach that enables the production of electrospun poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) nanofiber yarns using an automated parallel track system and an adjustable roll-to-roll collector. This research examines the impact of an automated post-drawing system on the polymer chain orientation, crystallinity, tensile strength, morphology, and piezoelectric properties of PVDF-HFP nanofiber yarn. The results reveal that the post-drawing process significantly improves molecular alignment, increases tensile strength, and enhances the …

Teaching Bioinformatics Through The Analysis Of Sars-Cov-2: Project-Based Training For Computer Science Students, Pavlin G Poličar, Martin Špendl, Tomaž Curk, Blaž Zupan

Faculty, Staff and Students Publications

MOTIVATION: We learn more effectively through experience and reflection than through passive reception of information. Bioinformatics offers an excellent opportunity for project-based learning. Molecular data are abundant and accessible in open repositories, and important concepts in biology can be rediscovered by reanalyzing the data.

RESULTS: In the manuscript, we report on five hands-on assignments we designed for master's computer science students to train them in bioinformatics for genomics. These assignments are the cornerstones of our introductory bioinformatics course and are centered around the study of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They assume no prior knowledge of molecular …

Enteric Fever In Children: An Epidemiological And Clinical Review Of Cases In Southeast Texas, Zachary C Foughty, Denver T Niles, Andrea T Cruz

Faculty, Staff and Students Publications

Extensively drug-resistant (XDR) strains of Salmonella enterica serotype Typhi have emerged in Pakistan and Iraq. We report 13 children with enteric fever in Southeast Texas seen over 3.5 years, of whom 23.1% had XDR isolates.

Using Human Intestinal Organoids To Understand The Small Intestine Epithelium At The Single Cell Transcriptional Level, Carolyn Bomidi, Xi-Lei Zeng, Victoria Poplaski, Cristian Coarfa, Mary K Estes, Sarah E Blutt

Faculty, Staff and Students Publications

Single cell transcriptomics has revolutionized our understanding of the cell biology of the human body. State-of-the-art human small intestinal organoid cultures provide ex vivo model systems that bridge the gap between animal models and clinical studies. The application of single cell transcriptomics to human intestinal organoid (HIO) models is revealing previously unrecognized cell biology, biochemistry, and physiology of the GI tract. The advanced single cell transcriptomics platforms use microfluidic partitioning and barcoding to generate cDNA libraries. These barcoded cDNAs can be easily sequenced by next generation sequencing platforms and used by various visualization tools to generate maps. Here, we describe …

Leveraging Artificial Intelligence To Adjust Staffing Levels In The Emergency Department, Marisel Perigo, Haydee Fernandez

All Publications

No abstract provided.

Digital Smart Room: Nurse-Led Innovation Implementation, Jessica Hucey Nua

All Publications

No abstract provided.

An Evaluation Of The Premack Contingency To Increase Physical Activity In Teenagers With Autism Spectrum Disorder, Shreeya S. Deshmukh

USF Tampa Graduate Theses and Dissertations

The United States Department of Health and Human Services (2018) recommends that teenagers engage in physical activity to improve their cardiovascular health and muscle and bone strength. Yet, most teenagers with and without autism spectrum disorder do not meet the recommended guidelines for physical activity. Research related to promoting physical activity has evaluated group contingencies, reinforcement-based interventions, and antecedent interventions; however, these interventions are time-intensive, require many resources, or are ineffective. The purpose of this study was to extend Allen and Iwata (1980) by reinforcing completion of a low-probability exercise to a specified criterion with access to a high-probability exercise. …

Considerations For Quality Control Monitoring Of Machine Learning Models In Clinical Practice, Louis Faust, Patrick Wilson, Shusaku Asai, Sunyang Fu, Hongfang Liu, Xiaoyang Ruan, Curt Storlie

Faculty, Staff and Student Publications

Integrating machine learning (ML) models into clinical practice presents a challenge of maintaining their efficacy over time. While existing literature offers valuable strategies for detecting declining model performance, there is a need to document the broader challenges and solutions associated with the real-world development and integration of model monitoring solutions. This work details the development and use of a platform for monitoring the performance of a production-level ML model operating in Mayo Clinic. In this paper, we aimed to provide a series of considerations and guidelines necessary for integrating such a platform into a team's technical infrastructure and workflow. We …

The Effect Of A Contextualized Dosage Calculation Learning Intervention On Pre-Nursing Students' Math Self-Efficacy And Ability To Pass High Stakes Dosage Calculation Examination On First Attempt, Eileen V. Weatherby

Dissertations

Many students in pre-licensure nursing programs struggle with calculating accurate medication dosages even though they meet the numeracy requirements for application to the nursing programs. Most pre-licensure programs require that nursing students pass dosage calculation exams at a specified level of accuracy before progressing to the next term. Students typically have three tries to pass at the specified level and should they not succeed, they must withdraw. If they wish to continue in the program, they must complete the requirements for reentry which may include space availability restrictions. Factors influencing dosage calculation performance include fear of mathematics, low math self-efficacy, …

Online Teacher-Student Rapport In Higher Education, Joshua Fitzgerald

Theses and Dissertations

Rapport developed between teachers and students in a typical classroom setting can provide students with a more positive school experience, an increase in learning and performance, and added feelings of social belonging (Cook, et al., 2018). Online learning is associated with many advantages like a more comfortable setting for students to participate (Majewska & Zvobgo, 2023), but also includes disadvantages like feelings of isolation (Phirangee & Malec, 2020) which can result in rapport being more difficult to develop. Established rapport during online educational settings can yield a multitude of positive outcomes for online students and teachers alike. These outcomes include …

Now And Ever Campaign Shatters Historic $1.5b Goal Early, Tina Hahn

University of Mississippi News

OXFORD, Miss. – With a pop of confetti and toasts of champagne, the University of Mississippi announced it has secured $1.5 billion for Now and Ever: The Campaign for Ole Miss, a goal passed more than a year ahead of schedule.

Aging- And Alcohol-Associated Spatial Transcriptomic Signature In Mouse Acute Pancreatitis Reveals Heterogeneity Of Inflammation And Potential Pathogenic Factors, Rachel R. Tindall, Yuntao Yang, Isabella Hernandez, Amy Qin, Jiajing Li, Yinjie Zhang, Thomas H. Gomez, Mamoun Younes, Qiang Shen, Jennifer M. Bailey-Lundberg, Zhongming Zhao, Daniel Kraushaar, Patricia Castro, Yanna Cao, W. Jim Zheng, Tien C. Ko

School of Medicine Faculty Publications

Abstract: The rapidly aging population is consuming more alcohol, leading to increased alcohol-associated acute pancreatitis (AAP) with high mortality. However, the mechanisms remain undefined, and currently there are no effective therapies available. This study aims to elucidate aging- and alcohol-associated spatial transcriptomic signature by establishing an aging AAP mouse model and applying Visium spatial transcriptomics for understanding of the mechanisms in the context of the pancreatic tissue. Upon alcohol diet feeding and caerulein treatment, aging mice (18 months) developed significantly more severe AAP with 5.0-fold increase of injury score and 2.4-fold increase of amylase compared to young mice (3 months). …

Loss Of Hormone Receptor Expression After Exposure To Fluid Shear Stress In Breast Cancer Cell Lines, Jonathan Cuccia, Braulio Andres Ortega Quesada, Ethan P. Littlefield, Alejandra M. Ham, Matthew E. Burow, Adam T. Melvin, Elizabeth C. Martin

School of Medicine Faculty Publications

Following metastatic spread, many hormone receptor positive (HR(+)) patients develop a more aggressive phenotype with an observed loss of the HRs estrogen receptor (ER) and progesterone receptor (PR). During metastasis, breast cancer cells are exposed to high magnitudes of fluid shear stress (FSS). Unfortunately, the role for FSS on the regulation of HR expression and function during metastasis is not fully understood. This study was designed to elucidate the impact of FSS on HR(+) breast cancer. Utilizing a microfluidic platform capable of exposing breast cancer cells to FSS that mimics in situ conditions, we demonstrate the impact of FSS exposure …