Digital Commons Network^™

A Case Of Reversible Acute Kidney Injury And Life-Threatening Gastrointestinal Bleed With Colitis In A Patient Receiving Tucatinib For Her2-Positive Breast Cancer, Geetha Keshav, Shanzae Naeem, Jalila Jafri

Advances in Clinical Medical Research and Healthcare Delivery

This case report describes the complex clinical course of a 73-year-old female with HER2-positive breast cancer enrolled in the CompassHER2 RD trial who developed acute kidney injury (AKI) requiring emergent hemodialysis shortly after initiation of tucatinib. In addition to severe renal dysfunction, the patient experienced a life-threatening lower gastrointestinal (GI) bleed in the setting of suspected drug-induced colitis and profound thrombocytopenia while receiving combination therapy with trastuzumab emtansine (T-DM1). Although tucatinib has demonstrated promising efficacy in improving outcomes for patients with high-risk HER2-positive disease, serious renal and gastrointestinal complications remain uncommon and underreported. This case underscores the importance of early …

Beyond The Algorithm: Empowering Clinicians And Researchers To Thrive In The Age Of Ai, Milan Sheth, Justin S. Brathwaite

Advances in Clinical Medical Research and Healthcare Delivery

Artificial intelligence (AI) is rapidly reshaping clinical research and healthcare delivery, yet meaningful adoption depends less on technical mastery and more on cultivating AI literacy among clinicians and research staff. Building a foundational understanding of concepts such as supervised learning, bias, and model validation enables professionals to interpret and apply AI-generated insights with confidence. Familiarity grows through exposure to AI-enabled electronic medical record systems, interdisciplinary collaboration with data scientists and informaticists, and small pilot projects that demonstrate workflow fit and real-world value. Prioritizing transparency, explainability, and ethical considerations ensures that AI augments clinical decision-making. Practical applications already span oncology research, …

Solutions To Dismantling Osteopathic Bias In American Medicine, Mathew Devine, Richard Terry

Advances in Clinical Medical Research and Healthcare Delivery

No abstract provided.

Addressing Doscrimination: Examining Bias Against Osteopathic Physicians, Sophia M. Valerino

Advances in Clinical Medical Research and Healthcare Delivery

Osteopathic medicine arose as a response to the limitations of conventional medical practices of the time. It emphasizes the body's innate ability to heal and the importance of holistic care and has since evolved into a rigorous and evidence-based system that parallels allopathic education in scope, standards, and licensure. Nevertheless, osteopathic physicians (DOs) continue to face systemic bias across multiple areas. This article examines the historical context and current manifestations of discrimination against DOs, highlighting disparities in residency selection, research participation, academic leadership, and media portrayal. Despite clear evidence showing comparable performance between DOs and MDs in clinical care and …

Vitamin D Deficiency And Risk Of Cognitive Decline And Dementia: Implications And Prevention Strategies, Auda Fares

Advances in Clinical Medical Research and Healthcare Delivery

Emerging evidence suggests a link between vitamin D deficiency and an increased risk of cognitive impairment and dementia, including Alzheimer's disease (AD). This paper reviews the epidemiological evidence, explores potential mechanisms underlying this association, and discusses implications for prevention strategies. Current supplementation strategies may not be fully effective due to individual variability. Personalized interventions based on genetic factors and routine vitamin D status testing in older adults are proposed as future directions for optimizing the impact of vitamin D supplementation in dementia prevention.

Nationwide Analysis Of Catheter-Directed Thrombolysis Versus Anticoagulation In Sub-Massive Pulmonary Embolism, Ayushma Acharya, Swarup Sharma Rijal, Anthony Donato

Advances in Clinical Medical Research and Healthcare Delivery

Background: Data on the real-world effectiveness and safety of catheter-directed thrombolysis (CDT) versus anticoagulation in sub-massive pulmonary embolism (PE) remain limited.

Objective: The aim of this study was to assess the differences in in-hospital mortality, length of stay (LOS), complications and healthcare resource utilization between catheter directed thrombolysis and anticoagulation in sub-massive pulmonary embolism using the National Inpatient Sample (NIS) dataset from 2016–2022.

Methods: The National Inpatient Sample (2016–2022) was queried to identify hospitalizations for sub-massive pulmonary embolism (PE) with cor pulmonale. Patients receiving CDT were compared to those treated with anticoagulation alone. We excluded patients with shock, ventilator …

Survival And Factors Associated With Mortality Among Patients With Oral Cancer At A Tertiary Hospital In Northeastern Thailand: A Retrospective Cohort Study, Somkiattiyos Woradet, Bhunyabhadh Chaimay, Nuntiput Putthanachote

Journal of Health Research

Background: Oral cancer is a major cause of premature mortality in Thailand. This study examines survival and prognostic factors in a northeastern tertiary-care setting.

Methods: A hospital-based retrospective cohort study was conducted using the Cancer Registry and medical records in a tertiary care hospital in Northeastern, Thailand. Patients diagnosed with oral cancer between January 2005 and December 2015 and followed until death or February 2020. Overall survival was estimated using the Kaplan–Meier method. Cox proportional hazards models were used to assess factors associated with mortality

Results: The median survival time was 18.67 months (95% confidence interval [CI]: 15.70–22.83). It revealed …

Associations Between Perceptions Of Indoor Environmental Quality And Satisfaction With Life Among Residents In Saudi Arabia, Hatim M. Badri, Wahaj A. Khan, Mohammad N. Shah, Osama A. Banah, Mohamed Osman Elamin, Rakan Ekram, Rayan Khayat, Abdullah Muhammad Alzhrani, Baraa Sami Quronfulah, Muath Ahmed Aldomini

Journal of Health Research

Background: Indoor residential environments influence physical and mental health, but evidence linking perceived Indoor Environmental Quality (IEQ) to Satisfaction With Life (SWL) in Saudi Arabia is limited. This study explored residents’ perceptions of IEQ and its association with SWL.

Methods: A cross-sectional online survey (March–April 2025) was conducted among adults (≥18 years) in Saudi Arabia using convenience sampling. A total of 451 participants completed a structured questionnaire. Data were analysed using descriptive statistics, Pearson correlations, one-way ANOVA, and multivariable logistic regression to identify IEQ predictors of low SWL (≤20), adjusting for age, sex, and BMI.

Results: …

Caregiving Experiences And Challenges Among Caregivers Of Children With Epilepsy In Thailand: A Qualitative Study, Arthittaya Kaenkrai, Pramote Thangkratok, Pawanrat Panjatharakul, Apasri Lusawat, Moritz Tacke

Journal of Health Research

Background: Childhood epilepsy requires long-term management and places substantial responsibilities on caregivers. In Thailand, limited public awareness and persistent stigma surrounding epilepsy may intensify caregivers’ psychosocial and practical burdens. This study aimed to explore the lived experiences of caregivers of children with epilepsy in Thailand.

Methods: A qualitative study using two semi-structured focus group discussions (FGDs; 5 participants per group) and 15 in-depth interviews (IDIs) was conducted with primary caregivers of children with epilepsy receiving care at a neurological referral institute in Thailand. Participants were purposively selected to capture a diverse range of caregiving experiences. Data were audio-recorded, transcribed verbatim, …

Hukum Pengadaan Barang (Government Procurement) Dan Pembangunan Ekonomi, Ade Maman Suherman

Jurnal Hukum & Pembangunan

Abstract

Anallsis Hukum Islam Terhadap Praktik Aborsi Bagi Kehamilan Tidak Diharapkan (Ktd) Akibat Perkosaan Menurut Undang-Undang Nomor 36 Tahun 2009 Tentang Kesehatan, Titik Triwulan Tutik

Jurnal Hukum & Pembangunan

Abstract

Korporasi Sebagai Pengemban Kewajiban Ham: Suatu Pencarian Legitimasi Dalam Hukum Internasional, Patricia Rinwigati Waagstein

Jurnal Hukum & Pembangunan

Abstract

Indonesia's Position Based On The Australian Asean New Zealand Free Trade Agreement And Its Impact From A Business La W Perspective, Ariawan Gunadi

Jurnal Hukum & Pembangunan

Abstract

The Necessity Of Capacity Building For Indonesia's Effective Utilization Of Wto Dispute Settlement Mechanism: Implementation Of Gait Article Xx For Trade And Environment Issues, Windu Kisworo

Jurnal Hukum & Pembangunan

Abstract

Peresepan Dokter: Organized Crime?, Agus Budianto

Jurnal Hukum & Pembangunan

Abstract

Catatan Singkat Mengenai Kedudukan Mpr Sesudah Perubahan Uud 1945, Fatmawati Fatmawati

Jurnal Hukum & Pembangunan

Abstract

Marketing College Football In The “New Normal”, Chris Croft, Tim Wilson

Atlantic Marketing Association Proceedings

No abstract provided.

Case: When Free Is Too Much To Pay, Rebecca Burcham

Atlantic Marketing Association Proceedings

No abstract provided.

Adoption And Diffusion Of At-Home Medical Tests, Jerome Christia

Atlantic Marketing Association Proceedings

No abstract provided.

Impressionism And Brand Identity, Rene Desborde, Kimball P. Marshall

Atlantic Marketing Association Proceedings

No abstract provided.

A Comparative Semiotic Analysis Of Promotional Philanthropic Public Texts In Persian And In English, Shaheen Borna Professor, Sushil Sharma Professor & Associate Dean, Russell Wahlers Associate Professor & Chair Mkg Department, Sameer Hajjar Assistant Professor

Atlantic Marketing Association Proceedings

No abstract provided.

Strategic Choices: A Case Study Of Media And Entertainment Industry Survival Of The Covid-19 Pandemic, Stephen C. Carlson

Atlantic Marketing Association Proceedings

No abstract provided.

We Can’T Get No Satisfaction: Analyzing Different Constructs Of Patient Satisfaction, Michael A. Petrochuk

Atlantic Marketing Association Proceedings

No abstract provided.

How Does Compensation Affect New Product Valuation?, Prachi Gala, Saim Kashmiri, Duncan Nicol

Atlantic Marketing Association Proceedings

No abstract provided.

Corporate Sociopolitical Activism On Instagram: Brand Responses To Covid-19 And Black Lives Matter, Cynthia B. Hanson

Atlantic Marketing Association Proceedings

No abstract provided.

Consumer Acquisition And Dissemination Of Phci On Social Media & Networks, Joe Cangelosi, Terry Damron, David Kim

Atlantic Marketing Association Proceedings

No abstract provided.

Comparison Of Selected Supply Chain Management Practices Of Three Major Regional/Metropolitan Hospitals, Alan D. Smith

Atlantic Marketing Association Proceedings

No abstract provided.

A Qualitative Study Of Business Leaders – Comparing Uncertainty Differences & Similarities During Covid Vs. 2008 - 2009, Ryan Matthews

Atlantic Marketing Association Proceedings

No abstract provided.

Comparison Of Concerns Among Careers By Marketing Seniors About Covid-19: Beginning Versus A Year Into The Pandemic, Alan D. Smith

Atlantic Marketing Association Proceedings

No abstract provided.

A Shift In The Respiratory Syncytial Virus Seasonal Pattern: A Single–Center Retrospective Study In Anhui, China (2023–2025), Yan Lu, Jie Zhang, Keran Zhu, Li Wang, Shenggang Ding, Liping Yuan

Journal of Pediatric Infectious Diseases

Objective: Before the coronavirus disease 2019 pandemic, respiratory syncytial virus (RSV)-related hospitalizations followed a predictable seasonal pattern in Anhui, China, typically beginning in November and lasting until March of the following year. However, city-specific data for Anhui were limited. This study investigated the epidemiological patterns and risk factors associated with severe RSV-associated lower respiratory tract infection (LRTI) among hospitalized children in our centre. Methods: We reviewed the records of children aged ≤14 years who were hospitalized with RSV lower respiratory tract infection between June 2023 and May 2025. RSV infection was confirmed using reverse transcription-polymerase chain reaction testing. Data on …