Digital Commons Network^™

The Importance Of Socialization: Family, School, Peer, And Media Influence On White Identity Development, Miandria Erickson

Honors Projects

This study aims to explore the different aspects of socialization that can impact one’s White racial identity development, in order to analyze why White individuals struggle to describe their racial identity. Acknowledging an individual’s White identity is an imperative aspect to understanding diversity and race, and yet, White individuals will often have difficulty recognizing and explaining their racial identity. This qualitative study used data collected from semi-structured interviews of 60 young White college participants (ages 18-25) in two different geographical locations, the Northwest and Southeast of the U.S.^[1] Several themes were extracted from these interviews, among them were family, …

Efficacy And Safety Of A Bodyweight-Adjusted Higher Dose Of Ocrelizumab In Relapsing (Musette) And Primary Progressive (Gavotte) Multiple Sclerosis: Two Multicentre, Randomised, Double-Blind, Parallel-Group Phase 3b Trials., Stephen L Hauser, Gavin Giovannoni, Xavier Montalban, Jiwon Oh, Amit Bar-Or, Maria Pia Sormani, Martin S Weber, Sharon Stoll, Jacqueline A Nicholas, Tetyana Nehrych, Robert Bonek, Krzysztof Selmaj, Maciej Maciejowski, Dusanka Zecevic, Catarina Raposo, Rebecca Owen, Ulrike Bonati, Katrin Madjar, Eva Harfst, Qing Wang, Anastasiia Raievska, Marianna Manfrini, Hans-Martin Schneble, Ludwig Kappos, Musette And Gavotte Study Groups

Neuroscience Articles

BACKGROUND: Ocrelizumab is a humanised anti-CD20 monoclonal antibody approved for people with relapsing (RMS) or primary progressive multiple sclerosis (PPMS). In a post-hoc analysis of phase 3 trials in RMS and PPMS using a 600 mg dose, higher exposure to ocrelizumab was associated with greater B-cell depletion and lower risk of confirmed disability progression. Here, we prospectively assessed the efficacy and safety of a high dose of ocrelizumab in patients with RMS or PPMS.

METHODS: Two multicentre, double-blind, phase 3 controlled trials were conducted to compare high-dose ocrelizumab with the approved 600 mg dose of the drug in patients with …

Is Trimethylamine N-Oxide A Friend, Foe, Or Hormetic Agent In Patients With Parkinson’S Disease: A Focused Review Of One Microbial Metabolite, Abraham B. Alton

Student Works

This review synthesizes recent literature examining trimethylamine N-oxide (TMAO) synthesis and its potential role in Parkinson’s Disease (PD) pathology. An increase in TMAO plasma and CSF concentration is associated with PD progression and severity. TMAO biosynthesis is a two-step process. First, precursors including carnitine and choline are converted to trimethylamine (TMA) by gut microbes. Second, TMAO is oxidized to TMAO in the liver. Once absorbed into circulation TMAO crosses the blood brain barrier and may influence PD disease pathology by increasing neuroinflammation and astrocyte activation and damaging the cerebral lymphatic system. These mechanisms may contribute to the cognitive and motor …

On The Brink Of Silence: Ethnographic Perspectives On Hunting And Forest Life Among The Awa Guajá In Eastern Amazonia, Uirá Garcia

Tipití: Journal of the Society for the Anthropology of Lowland South America

The central theme of this article basically resides in the relationship established by indigenous peoples between their hunting practices and the forest. Indigenous ways of connecting ‘hunting’ and ‘forest’ necessarily pass through other modes of knowing, only marginally – if it all – dependent on vision. On the contrary, sounds, smells and even dreams are, for many South American indigenous collectives, more trustworthy indices than what the eye sees. This article divides into two parts. In the first, I set out the main ideas related to the anthropological study of hunting in Amazonia at a conceptual level. In the second, …

Self-Reported Gum Bleeding, Oral Health Behaviors, And Cardiovascular Risk Indicators Among Adults Aged 45-70 In A Community Dental Setting., Kimberleigh Edwards

Population Health Leadership and Analytics Theses

Cardiovascular disease remains a leading cause of morbidity and mortality among adults in the United States, particularly during midlife and older adulthood. Periodontal inflammation and poor oral hygiene behaviors have been linked to increased cardiovascular risk through systemic inflammatory pathways. This exploratory cross-sectional study described patterns of self reported gum bleeding, oral hygiene behaviors, and cardiovascular risk factors among 29 adults aged 45 to 70 at a community dental clinic using the researcher-developed Oral and Heart Health Study Questionnaire. Fourteen participants reported both gum bleeding and at least one cardiovascular risk factor. Participants who reported inconsistent flossing and infrequent professional …

Working Out Your Self-Image: Strength, Self-Esteem, And Human Flourishing, Kingston K. Christie

Honors Projects

This project integrates empirical research in exercise science with theological anthropology to examine the psychological effects of resistance training and the meaning of strength within a Christian framework of human dignity and flourishing. The empirical component investigated the effects of a four-week progressive resistance training intervention on global self-esteem and physical self-concept among undergraduate university students with moderate-to-low baseline self-esteem. Eleven participants (N = 11; 20.15 ± 1.52 yrs) completed the Rosenberg Self-Esteem Scale (RSES) and Physical Self-Description Questionnaire Short Form (PSDQ-S) before and after the intervention, with muscular strength assessed via submaximal testing across the squat, bench press, deadlift, …

Trends Towards Political Communication Strategy On Social Media: A Bibliometrics Analysis, Annisa Atha Hanifah, La Mani, Zidane Ahmad Busthomi, Giovanni Sunrise, Matthew A. Kristanto, Indra Prawira

Jurnal Wacana Politik

Social media has become the center of digital political communication, enabling politicians to convey messages, form narratives, and mobilize public support directly and interactively. Social media platforms such as Twitter, Instagram, and TikTok serve not only as campaign tools but also as deliberative spaces where political discourse is formed and debated. This study uses a bibliometric approach to analyze global trends in research on political communication on social media during the period 2020-2024. Data were collected in October 2025 from Scopus database, comprising 608 documents from 253 publication sources and author affiliations in 24 countries. The search was conducted using …

Cultural Determinism, Leadership Identity, And Psychological Outcomes Among Emirati Women School Principals: A Convergent Mixed Methods Study, Saeed Mobarak Alkaabi

All Works

Background/problem: Despite state-led empowerment reforms in the United Arab Emirates (UAE), Emirati women school principals experience tension between leadership roles and entrenched cultural expectations. Norms related to family honor, modesty, male guardianship, and relational harmony, continue to shape leadership identity formation, agency, and psychological outcomes, influencing leadership legitimacy and professional identity. Objective/purpose: This study examines how cultural determinism influences leadership identity, agency, and psychological well-being among Emirati women school leaders on the East Coast of the UAE. Design and Methodology: A convergent parallel mixed methods design was implemented. Correlation and regression analysis were used to test the influence of cultural …

Iterative Cannabis Care Plans Are Associated With Higher Rates Of Symptom Relief And Lower Side-Effect Burden In Oncology Patients, Brooke Worster, Md, Kristen Parton, Mba, Gregory Garber, Msw

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

Background/Research Objective

Cannabis is increasingly used to manage cancer-related symptoms including pain, sleep disturbance, anxiety, and appetite or gastrointestinal complaints. However, patient responses are highly variable, clinicians report limited confidence in guiding use, and optimal dosing is difficult to predict from baseline characteristics. We evaluated whether an iterative, guided cannabis care model incorporating ongoing patient feedback and care-plan adjustments is associated with improved symptom relief and lower side-effect burden in a real-world oncology population.

Impetus 2025 – The Philippine Physical Therapy Association (Ppta) National Convention: Poster Presentations, Impetus 2026

Philippine Journal of Physical Therapy

No abstract provided.

Impetus 2025 – The Philippine Physical Therapy Association (Ppta) National Convention: Platform Presentations, Impetus 2026

Philippine Journal of Physical Therapy

No abstract provided.

A Call To Action: Towards A Compendium For Culturally Responsive And Inclusive Pain Management, Arvie Vitente, Rob Sweet, Lester Jones

Philippine Journal of Physical Therapy

Introduction: Pain is a pervasive global health problem, yet its assessment and management remain shaped by biomedical, monolingual, and culturally narrow assumptions that do not fully reflect the lived realities of diverse populations. Although contemporary pain science recognizes pain as a personal experience influenced by biological, psychological, and social factors, inequities persist across racial, ethnic, linguistic, and cultural groups.

Main Body: These inequities affect how pain is expressed, interpreted, documented, and treated, particularly among Indigenous peoples, migrants, refugees, and patients with limited English proficiency. In this perspective, we call for the development of a comprehensive compendium on culturally responsive and …

Leveraging Social Media Recruitment In Health Science Education: A Scoping Review, Crystalyn Richard, Natalie Nguyen, Luong Thien Nguyen, Alison Hansen

Philippine Journal of Physical Therapy

Background: Equitable recruitment practices are essential to the diversification of health science educational applicant pools. This scoping review aimed to understand the existing literature supporting the use and implementation of SM (SM) for recruitment in various health science educational programs. Methods: A comprehensive search utilizing the PRISMA Extension for Scoping Reviews (PRISMA-ScR) framework was used to collect and analyze existing articles. Keyword selection followed by an iterative process for article inclusion using Covidence application for article analysis and inclusion/exclusion. A thematic analysis method was employed to synthesize findings from the studies that met our inclusion criteria. Results: The initial keyword …

Clinician Perspectives On Fistula Mental Health, Victoria K. Leonard

Doctoral Dissertations

Background – Obstetric fistula is a childbirth injury caused by prolonged labor that leads to stillbirth and incontinence, spurring social exclusion and isolation. These layers of trauma put women with fistula at great risk for psychological suffering, which has profound negative socioeconomic impacts on them, their families, and communities. This study captured treatment as usual at Comprehensive Community Based Rehabilitation in Tanzania (CCBRT), the country’s largest provider of fistula care.

Method – Improving holistic fistula treatment requires engaging the clinicians who care for women with fistula. This study aimed to investigate the training, beliefs, and treatment approaches of nurses and …

Rocatinlimab As A Novel Treatment Strategy For Atopic Dermatitis, Haylee Whyde, Evan Blazek, Macy Davis, Parker George, Alex Lowery, Connor Dains, Brenna Hissong, David Koh

Pharmacy and Wellness Review

Atopic dermatitis is a common chronic inflammatory skin disease that affects millions of children and adults in the United States. Atopic dermatitis is characterized by recurrent pruritus, erythema, and relapsing symptoms that can significantly impair quality of life. The pathophysiology of atopic dermatitis involves epidermal barrier dysfunction, immune dysregulation, and genetic susceptibility. Atopic dermatitis guidelines follow a stepwise approach that begins with a severity assessment, trigger avoidance, and nonpharmacologic and pharmacologic treatments. First-line therapies include topical corticosteroids (TCSs), topical calcineurin inhibitors (TCIs), and emollients. Crisaborole and topical ruxolitinib are used for mild-to-moderate disease when prior therapy has been inadequate. Monoclonal …

Fda Approval Of Tradipitant: A Novel Approach To Motion Sickness Treatment, Haley Brown, Jennifer Cao, Allie Honigford, Leah Heitkamp, Sarah Hiett, Connor Dains, Brenna Hissong, Manoranjan D'Souza

Pharmacy and Wellness Review

Motion sickness is a prevalent neurophysiological condition affecting approximately one-third of the worldwide population, resulting from sensory mismatch and the brain’s internal model of motion. It is characterized by nausea, vomiting, dizziness, and autonomic symptoms during exposure to actual or virtual motion, which may significantly impair daily functioning and quality of life. Current guidelines recommend the prevention and treatment of motion sickness through pharmacologic, herbal, and non-pharmacologic strategies. Scopolamine and first-generation antihistamines are effective pharmacologic options, while ginger has demonstrated some benefit in reducing symptoms as an herbal option. Non-pharmacologic interventions such as habituation training, behavioral techniques, and sensory strategies …

Between The Root And The Stem: On Women-Plant Relations, Predation And Familiarisation Among The Awajún (Upper Amazonas, Peru), Nils Haukeland Vedal

Tipití: Journal of the Society for the Anthropology of Lowland South America

What to do with the problem of predation? This is not only a conundrum for anthropologists working in what has become known as animist societies. The gardening activities of the Awajún people of northern Peru’s high jungle are modelled on the teachings of the original mother of cultivated plants, Núgkui, who granted the Awajún their cultivars. Yet gardening is not an easy matter. The manioc sprouts seek to suck the blood of gardeners unless they are treated correctly. This article explores how predation is constantly kept at bay through familiarisation practices in which garden plants are made into the vegetative …

Making Noise Through Law: Indigenous Legal Mobilisation Against A Power Plant In “French” Guiana, Pierre Auzerau

Tipití: Journal of the Society for the Anthropology of Lowland South America

In so-called “French” Guiana, or Guyane, the Kali’na village of Atopo Wipi has fought for years against a hydrogen power plant being built on their land. Drawing on ethnographic fieldwork conducted between 2023 and 2024 in Guyane and Western Europe, where I collaborated with various stakeholders to support Atopo Wipi’s resistance to the power plant, my research focuses on the legal dimensions of the Kali’na’s struggle to protect their land. Specifically, this article examines how the Kali’na navigated different normative frameworks, including international human rights standards and French law, to fight the project. Through this analysis, I show how the …

Navigating Trust: The Impact Of Social Media Influencers On Gen Z Health Behaviors, Abigail Stelling

Honors Thesis

Social media plays a defining role in the daily lives of Gen Z, influencing how people communicate, access information, and make decisions. More than a form of entertainment, social media is a powerful source that shapes identity, perceptions, and behaviors. As the first generation to grow up fully immersed in a digital world, Gen Z is uniquely impacted by the content and interactions that occur on social media platforms. Within this digital landscape, social media influencers have emerged as powerful figures. These individuals use large online platforms to promote lifestyles, products, and behaviors. Influencers often have the ability to shape …

“Ese Dia Que Se Va El Patron An Hecho Fiesta”.* Historicities Of Successful Resistance Against Hacienda Bosses Among The Kukama (Peru, 1933-1945), Arno R. Holl

Tipití: Journal of the Society for the Anthropology of Lowland South America

This paper analyzes two cases of resistance by Kukama workers within the debt slavery system of habilitación in the Peruvian Amazon during the first half of the twentieth century. It discusses the similarities and differences between the two cases, and positions the workers and their accounts of events and agency within the historical, social and cosmological framework of the time and region. Through the examples studied here, the hierarchies, power dynamics, spirituality, lifestyles, traditions, and cultural changes that shaped Kukama communities at the time become visible from an emic perspective. The paper places special emphasis on how historical events are …

Debatrix, Vivienne Lu, Huy Ngo, Luke Ponssen, Jonathan Preiss, Ryan Rani

Computer Science and Engineering Senior Theses

Developing public-speaking skills remains a persistent challenge in formal education, constrained by limited instructional time and the lack of scalable, individualized feedback. Existing automated tools address only narrow aspects of this problem, offering text-based coaching against rigid rubrics that fail to capture argument quality, evidence use, or real-time rebuttal skill. This thesis presents Debatrix, an AI-powered platform that enables K-12 students, university learners, and independent self-studiers to debate an intelligent opponent. The system combines automatic speech recognition, large language model-driven rebuttal generation, and a multi-dimensional rhetorical analysis engine that evaluates argument structure, evidence integration, and persuasive technique. Users receive explainable …

Evaluating The Market Withdrawal Of Andexanet Alfa, Jordyn Linfield, Addisyn Cooper, Alexander Defranco, Emma Gerding, Jessica Kelley, Tyler Henney, Connor Dains, Brenna Hissong, Brittany Bates

Pharmacy and Wellness Review

The coagulation cascade comprises intrinsic, extrinsic, and common pathways that converge when thrombin converts fibrinogen (factor I) into fibrin, leading to fibrin mesh formation, stabilization of the platelet plug, and ultimately thrombus formation. Inhibition of the coagulation cascade can be achieved with a variety of anticoagulant medications, including direct oral anticoagulants (DOACs). The mechanism of action of DOACs is to inhibit either factor Xa or thrombin. Reversal of anticoagulation remains an important clinical consideration when managing patients on DOACs who experience serious bleeding events. Andexanet alfa is a recombinant, modified human factor Xa protein previously indicated for patients receiving rivaroxaban …

Fda Approval Of Etripamil For The Treatment Of Paroxysmal Supraventricular Tachycardia, Kiley Devoll, Daniella Egbujor, Katy Grainger, Katherine Cook, Victoria Niese, Connor Dains, Brenna Hissong, Andrew Roecker

Pharmacy and Wellness Review

Paroxysmal supraventricular tachycardia (PSVT) is characterized by sudden, brief, intermittent episodes that result in a heart rate of 150 to 250 beats per minute (bpm). PSVT is difficult to diagnose, making proper treatment challenging. According to the 2015 American Heart Association (AHA)/American College of Cardiology (ACC)/Heart Rhythm Society (HRS) guidelines, current pharmacologic recommendations for PSVT include adenosine, verapamil, diltiazem, or nonpharmacologic vagal maneuvers.¹ These treatments each have a variety of adverse effects, contraindications, and dosing considerations, which highlight a need for novel therapies for the acute treatment and maintenance of PSVT.¹ The NODE-301 trial assessed the safety and …

Beyond Behavior: Understanding Trauma As A Pathway To Transform Classroom Discipline, Jennifer J. Snead

Masters Projects

Many students entering early childhood and elementary classrooms have experienced trauma that impacts their ability to learn, regulate emotions, and fully participate in school. Research shows that adverse childhood experiences (ACEs) can affect brain development, particularly in areas related to attention, memory, and self-regulation—skills essential for success in the classroom. Even though trauma-related behaviors are becoming more common, many educators report feeling underprepared to recognize and respond to these behaviors due to limited training in trauma-informed practices. As a result, student behavior is often misunderstood as defiance, which can lead to discipline practices that do not address the root cause. …

Rural-Urban Differences In Hypertension Prevalence And Control In A Large Regional Health System Cohort, Yordanos M Tiruneh, Susan Mcbride, Huaxin Song, Matthew Decaro, Alaa Rihan, Theresa Byrd, Alex Baham, Jared W Magnani, Elmer V Bernstam, Jarett D Berry

Faculty, Staff and Student Publications

Background: Rural US populations bear a high burden of cardiovascular disease, with hypertension contributing to the rural-urban gap. We examined hypertension prevalence and control across the rural-urban continuum among patients in a large healthcare system in Northeast Texas.

Methods: We analyzed the electronic health record data from 363,539 patients with at least one outpatient encounter between September 2021 and April 2025. We defined hypertension using ICD-10-CM codes, antihypertensive prescriptions, or a blood pressure ≥ 130/80 mm Hg. We classified rurality using the Rural-Urban Commuting Area categories. Multivariable logistic regression models were adjusted for age, sex, race, ethnicity, insurance, and level …

Effects Of A 10-Day Remote Ischemic Preconditioning Protocol On Anaerobic And Aerobic Performance And Post-Exercise Cytokine Responses, Paulina Brzezińska, Jan Mieszkowski, Madalena Kochanowicz, Andżelika Borkowska, Jędrzej Antosiewicz, Andrzej Kochanowicz

Baltic Journal of Health and Physical Activity

Background: Remote ischemic preconditioning (RIPC) consists of brief cycles of limb is-chemia and reperfusion and has been proposed as an ergogenic strategy. This study examined whether a 10-day lower-limb RIPC protocol affects anaerobic and aerobic performance and post-exercise cytokine responses in physically active men. Materials and methods: Sixty healthy, physically active men were assigned to anaerobic (Wingate Anaerobic Test (WAnT), n = 29) or aerobic (Bruce treadmill test (BTT), n = 28) protocols and completed a 10-day lower-limb RIPC (220 mmHg) or SHAM (20 mmHg) intervention. Serum IL-6, IL-10, and IL-15 were measured at baseline and immediately post-exercise before and …

Simplification Of Technical Language In Tagesschau News For B1-Level German Vocabulary Learning, Syaula Qonit Helga, Dewi Kartika Ardiyani

Journal of Innovation and Teacher Professionalism

This study aims to identify and categorize the types of Fachsprache (specialized language) found in simplified Tagesschau news and to explore their potential use for B1-level German vocabulary learning. The study employs a qualitative descriptive approach using content analysis. Data were collected from news videos available on the Tagesschau YouTube channel and analyzed according to three categories: (1) CEFR level, (2) subject area, and (3) usage context. The data were processed through data reduction techniques to simplify Fachsprache terms at higher CEFR levels, followed by data display and interpretation to examine the identification results, and finally, conclusion drawing. The findings …

Can Behavioral Interventions Promote Health Equity In Pediatric Type 1 Diabetes? A Narrative Review Of Promising Treatments, Paul T. Enlow, Jaquelin Flores Garcia, Julia Price, Kristen A. Torres, David V. Wagner

Department of Pediatrics Faculty Papers

Purpose of review: Synthesize data on whether existing behavioral interventions can improve health equity among youth with type 1 diabetes.

Recent findings: While existing behavioral interventions demonstrated efficacy in improving health and/or psychosocial outcomes, evidence that these same interventions may improve health equity were lacking. Most interventions were evaluated using predominantly White and affluent samples and some studies did not report on racial, ethnic, or sociodemographic characteristics of their sample. Only a few interventions have been adapted for youth from minoritized backgrounds. Recent multisystemic and technology/mHealth interventions recruited samples that were sociodemographically representative of youth experiencing disparities, suggesting that these …

Choline Counteracts Pregnancy Undernutrition-Associated Colitis In Sheep By Restoring Microbiota Driven Bile Acid Metabolism, Weibin Wu, Peng Jiao, Yamei Gu, Huizhen Lu, Caiyun Fan, Zheng Sun, Lizhuang Hao, Shengyong Mao, Jianbo Cheng, Yanfeng Xue

Faculty, Staff and Students Publications

High-fertility sheep experience undernutrition during late gestation, which induces body metabolic disruption and intestinal inflammation. Crucially, the gut microbiota-bile acid axis is a promising intestinal inflammation target, but how choline modulates this axis in livestock enteritis is unknown. This study investigated choline's protective mechanisms against undernutrition-induced intestinal inflammation in sheep, focusing on gut microbiota and bile acid regulation. Choline consistently alleviates colitis severity, restores epithelial barrier integrity, and suppresses intestinal inflammation. These protective effects are accompanied by pronounced remodeling of the colonic microbial ecosystem, characterized by the enrichment of Clostridiales bacterium to elevate bile salt hydrolase activity and regulate bile …

Coxfa4l2 Upregulation Preserves Residual Cytochrome C Oxidase Activity In Coxfa4-Related Leigh-Like Encephalopathy, Micol Falabella, Sandra Lopez Calcerrada, Jana Aref, Jiaze Gao, William L Macken, Chiara Pizzamiglio, Renata Kabiljo, Anna Lucia Francavilla, Pauline Gaignard, Antoine Pouzet, Jonathan Levy, Giulia Barcia, Jamie K Leighton, Efstathia Chronopoulou, Germaine Pierre, Riza Köksal Özgül, Ali Dursun, Rebecca Halligan, Helen Mundy, Javeria Raza Alvi, Tipu Sultan, William James Craigen, Lisa Emrick, Jill A Rosenfeld, Gehad Elmakkawy, Jihye Kim, Joseph J Gleeson, Aboulfazl Rad, Gabriela Oprea, Maqbool Hussain, Khalil Ur Rehman, Sadia Riaz, Robert W Taylor, Vincent Procaccio, Maha S Zaki, Erika Fernandez-Vizarra, Ciro Leonardo Pierri, Michael G Hanna, Henry Houlden, Reza Maroofian, Cristina Ugalde, Jan-Willem Taanman, Robert D S Pitceathly

Faculty, Staff and Students Publications

Primary mitochondrial diseases (PMDs) affect approximately 1 in 4300 individuals and cause early-onset neuromuscular and multisystem dysfunction with reduced lifespan. They result from pathogenic variants in mitochondrial or nuclear DNA that impair oxidative phosphorylation. Cytochrome c oxidase (COX; complex IV) deficiency is a well-established cause of PMD, leading to a broad spectrum of phenotypes. COXFA4 (cytochrome c oxidase subunit FA4), formerly NDUFA4, is a nuclear-encoded COX subunit, but its role in disease remains poorly defined. We report the largest genetically confirmed cohort of COXFA4-related PMD to date, comprising 13 individuals from 12 families with biallelic pathogenic COXFA4 variants. All present …