Digital Commons Network^™

Staff Education To Expand Clinicians’ Knowledge Of Standardized Screening Tools In Addiction Treatment, Uwaezu Mercy Kalu

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project focuses on a staff education initiative to enhance clinicians' knowledge and application of standardized screening tools for co-occurring mental health disorders in addiction treatment settings. The project addresses inconsistencies in screening practices that contribute to undiagnosed mental health conditions, adversely affecting patient outcomes. Clinicians were trained to use three validated tools: PHQ-9 for depression, GAD-7 for anxiety, and MDQ for bipolar disorder. The intervention involved a structured educational program with pre- and post-intervention assessments. Results showed significant improvement in clinicians' knowledge, with pretest scores averaging 4.6 and posttest scores averaging 6.0 (p < 0.05). The findings highlight the effectiveness of standardized tools in improving diagnostic consistency and care quality. Key recommendations include integrating these tools into routine clinical assessments, standardizing documentation practices, fostering interdisciplinary collaboration, and establishing continuous quality improvement processes. Despite limitations such as small sample size and single-site implementation, this project underscores the critical role of staff education in promoting evidence-based practices to improve patient outcomes and supports positive social change in addiction treatment settings.

Perceptions Of Early Childhood System Partners On Career Pathways, Melissa Larson Busby

Walden Dissertations and Doctoral Studies

Researchers have found high-quality early childhood teachers are crucial to high-quality programs for young children. Despite this, there is a significant need for more highly qualified teachers in a southwestern state. The purpose of the qualitative study was to explore the perceptions of early childhood education (ECE) systems partners in one southwestern state regarding the current systems, structures, and policies related to career pathways through the high school, community college, and university levels. The conceptual framework for this study was based on von Bertalanffy’s general systems theory and systems thinkers such as Senge, who detail the complex interactions between systems …

New Graduate Nurses' Experiences Of Burnout As They Transition To Practice, Stacy Beth Elliott

Walden Dissertations and Doctoral Studies

Transitioning from nursing school to professional practice is a critical and challenging period for newly graduated nurses. Transition to professional nursing practice is particularly stressful in the first 3 years as new graduates adapt to the high acuity of patient care, which can result in burnout. The purpose of this qualitative study, guided by the conservation of resource theory, was to understand how new graduate nurses describe their experiences of burnout as novice nurses transition in the first 3 years of nursing practice. Fourteen nurses were interviewed using a semi-structured interviews, and Saldana’s two-cycle analysis was used for data interpretation, …

Geneseo Authors Celebration 2024, Milne Library

Geneseo Authors Celebration

Milne Library began a tradition of celebrating faculty authorship in 2009 with a series of workshops and a celebration in collaboration with the Teaching and Learning Center. Over the years it has evolved to more accurately reflect on the variety of academic and creative work done here at Geneseo. The annual Geneseo Authors Celebration is an opportunity for the Library and the campus to celebrate the faculty and truly acknowledge the time and effort that faculty have invested into creating exceptional works that contribute to the scholarly discussions taking place in their disciplines.

In late fall 2024, when the Geneseo …

Loss Of Chop Prevents Joint Degeneration And Pain In A Mouse Model Of Pseudoachondroplasia, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Michele Carrer, Frankie Chiu, Dorde Relic, Paymaan Jafar-Nejad, Karen L Posey

Faculty, Staff and Student Publications

Pseudoachondroplasia (PSACH), a severe dwarfing condition characterized by impaired skeletal growth and early joint degeneration, results from mutations in cartilage oligomeric matrix protein (COMP). These mutations disrupt normal protein folding, leading to the accumulation of misfolded COMP in chondrocytes. The MT-COMP mouse is a murine model of PSACH that expresses D469del human COMP in response to doxycycline and replicates the PSACH chondrocyte and clinical pathology. The basis for the mutant-COMP pathology involves endoplasmic reticulum (ER) stress signaling through the PERK/eIF2α/CHOP pathway. C/EBP homologous protein (CHOP), in conjunction with a TNFα inflammatory process, upregulates mTORC1, hindering autophagy clearance of mutant COMP …

Perceptions Of Early Childhood System Partners On Career Pathways, Melissa Larson Busby

Walden Dissertations and Doctoral Studies

Researchers have found high-quality early childhood teachers are crucial to high-quality programs for young children. Despite this, there is a significant need for more highly qualified teachers in a southwestern state. The purpose of the qualitative study was to explore the perceptions of early childhood education (ECE) systems partners in one southwestern state regarding the current systems, structures, and policies related to career pathways through the high school, community college, and university levels. The conceptual framework for this study was based on von Bertalanffy’s general systems theory and systems thinkers such as Senge, who detail the complex interactions between systems …

Hiring, Training, And Retaining Mental Health Professionals At Rural Wisconsin Correctional Facilities, Jessica Kallenbach

Walden Dissertations and Doctoral Studies

Correctional facilities in rural Wisconsin have noted a shortage of trained mental health professionals to provide care. Common barriers to providing mental health services in rural areas are the availability and accessibility of mental health professionals. Due to limited access to financial and career benefits, mental health professionals tend to avoid working in these areas. The purpose of this qualitative phenomenological study was to explore the lived experience of mental health professionals, administrators, and supervisors in hiring, training, and retaining staff in rural Wisconsin correctional facilities. Bandura’s social learning theory was used to guide the study. Data was collected from …

Corporate Social Responsibility, Economic, Ethical-Legal, And Philanthropic Performances In Ghanaian Banks Using Big Data Analytics, Mohammed Alhassan Adams

Walden Dissertations and Doctoral Studies

Corporate social responsibility (CSR) is becoming increasingly essential for Ghanaian banks to reconcile financial growth with ethical, legal, and civic obligations amid escalating societal expectations. The specific research problem was that the extent to which Ghanaian banks employed big data analytics (BDA) to boost multidimensional CSR performance encompassing economic, ethical-legal, and philanthropic dimensions was unknown. The purpose of this quantitative correlational study was to examine the potential impacts of BDA use and overall CSR performance on Ghanaian banks’ economic, ethical-legal, and philanthropic dimensions of CSR. Using stakeholder theory and a resource-based view, BDA was applied as a strategic tool for …

Perceptions Of Black Women’S Portraits Of Beauty In Essence Magazine, Dr. Rachel Mingo

Walden Dissertations and Doctoral Studies

Historically, beauty standards in the United States were rooted in White ideals, influencing media portrayals of Black women to align with White features like lighter skin and straightened hair. Although recent studies suggest a slow shift toward a more diverse representation of Black beauty, depictions in magazines still predominantly reflect mainstream Western beauty ideals, leading to potential negative impacts on Black women’s self-esteem and body image. The purpose of this generic qualitative study was to explore how young Black women, ages 18–25, perceive portrayals of Black beauty in Essence magazine. Black feminist thought constituted the theoretical basis for this study. …

New Graduate Nurses' Experiences Of Burnout As They Transition To Practice, Stacy Beth Elliott

Walden Dissertations and Doctoral Studies

Transitioning from nursing school to professional practice is a critical and challenging period for newly graduated nurses. Transition to professional nursing practice is particularly stressful in the first 3 years as new graduates adapt to the high acuity of patient care, which can result in burnout. The purpose of this qualitative study, guided by the conservation of resource theory, was to understand how new graduate nurses describe their experiences of burnout as novice nurses transition in the first 3 years of nursing practice. Fourteen nurses were interviewed using a semi-structured interviews, and Saldana’s two-cycle analysis was used for data interpretation, …

Targeted Degradation Of Oncogenic Krasg12v Triggers Antitumor Immunity In Lung Cancer Models, Dezhi Li, Ke Geng, Yuan Hao, Jiajia Gu, Saurav Kumar, Annabel T Olson, Christina C Kuismi, Hye Mi Kim, Yuanwang Pan, Fiona Sherman, Asia M Williams, Yiting Li, Fei Li, Ting Chen, Cassandra Thakurdin, Michela Ranieri, Mary Meynardie, Daniel S Levin, Janaye Stephens, Alison Chafitz, Joy Chen, Mia S Donald-Paladino, Jaylen M Powell, Ze-Yan Zhang, Wei Chen, Magdalena Ploszaj, Han Han, Shengqing Stan Gu, Tinghu Zhang, Baoli Hu, Benjamin A Nacev, Medard Ernest Kaiza, Alice H Berger, Xuerui Wang, Jing Li, Xuejiao Sun, Yang Liu, Xiaoyang Zhang, Tullia C Bruno, Nathanael S Gray, Behnam Nabet, Kwok-Kin Wong, Hua Zhang

Faculty, Staff and Student Publications

Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most frequently mutated oncogene in lung adenocarcinoma, with G12C and G12V being the most predominant forms. Recent breakthroughs in KRASG12C inhibitors have transformed the clinical management of patients with the G12C mutation and advanced our understanding of the function of this mutation. However, little is known about the targeted disruption of KRASG12V, partly due to a lack of specific inhibitors. Here, we leverage the degradation tag (dTAG) system to develop a KRASG12V-transgenic mouse model. We explored the therapeutic potential of KRASG12V degradation and characterized its effect on the tumor microenvironment (TME). …

Corporate Social Responsibility, Economic, Ethical-Legal, And Philanthropic Performances In Ghanaian Banks Using Big Data Analytics, Mohammed Alhassan Adams

Walden Dissertations and Doctoral Studies

Corporate social responsibility (CSR) is becoming increasingly essential for Ghanaian banks to reconcile financial growth with ethical, legal, and civic obligations amid escalating societal expectations. The specific research problem was that the extent to which Ghanaian banks employed big data analytics (BDA) to boost multidimensional CSR performance encompassing economic, ethical-legal, and philanthropic dimensions was unknown. The purpose of this quantitative correlational study was to examine the potential impacts of BDA use and overall CSR performance on Ghanaian banks’ economic, ethical-legal, and philanthropic dimensions of CSR. Using stakeholder theory and a resource-based view, BDA was applied as a strategic tool for …

Generative Ai In Shariah Advisory In Islamic Finance: An Experimental Study, Muhammad Noman Jokhio, Muhammad Asif Jaffer

Business Review

Islamic banks adhere strictly to Shariah principles in all operations and offerings, creating a demand for experts proficient in Shariah-compliant banking and finance. This study investigates the potential of using generative AI, specifically Large Language Models (LLMs), to provide Shariah advisory in complex Islamic financing scenarios. The research evaluates general purpose public LLMs—such as ChatGPT, Gemini, and Meta AI—on their ability to identify Shariah compliance issues, cite relevant Shariah references, and propose actionable guidance for resolving compliance challenges in complex Islamic financing scenarios. A qualitative approach was used. The experimental study involved creation of complex, realistic financing scenarios requiring Shariah …

Re: Silver Bow Creek Butte Area Npl Site Spring Semi-Annual 2024 Butte Priority Soils Operable Unit Interim Site-Wide Groundwater Monitoring Data Report. Consent Decree- Civil Action No. Cv 89-039-Bu-She, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Population-Based Study Of The Epidemiology Of Stiff Person Syndrome In A Large Colorado-Based Health System, Paul Daniel Crane, Stefan Sillau, Renee Dreher, Rikki Fix, Phillip Winters, Russell Van Coevering, Eric Engebretson, Brooke Valdez, Elizabeth Matthews, Kavita V. Nair, Aaron M. Carlson, Amanda L. Piquet

Student Publications

Background and objectives: Stiff person syndrome spectrum disorder (SPSD) is a rare autoimmune disorder characterized by progressive muscle stiffness and painful spasms with an estimated prevalence of 1-2 cases per million people. Population-based epidemiologic studies are lacking because of both poor patient capture and the lack of standardized diagnostic criteria. Objectives of this study were to describe the incidence and prevalence of SPSD within the University of Colorado Health (UCH) system and apply previously proposed published criteria for SPSD within this population.

Methods: We queried Health Data Compass, an electronic health data repository for a large academic health care system, …

Epithelial Barrier Hypothesis: A Systematic Review, Krishna Patel, Peter Lio

Student Publications

Background

The epithelial barriers, which include the skin, the gut, and the respiratory lining, play a crucial role in protecting the body from pathogens and environmental threats. Many harmful toxins are increasingly part of modern life. The increase in usage of these damaging agents in conjunction with the increase in allergic inflammatory conditions suggests that the “epithelial barrier hypothesis”—the concept that damage to the epithelia by external agents can result in dysbiosis, inflammation, and allergy—may explain the rise in these conditions seen in the developed world.

Objective

We sought to assess the evidence for the epithelial barrier hypothesis, with particular …

Engagement With Professional Stakeholders In Healthcare Research—The Case Of The Dementia Personalised Care Team (D-Pact) Project In The United Kingdom, Basharat Hussain, Hannah Wheat, Tomasina M. Oh, Richard Byng

Peninsula Medical School

Introduction: In this viewpoint we highlight a gap in the literature relating to the involvement of professional stakeholders in healthcare evaluation research. Method: Using the Dementia—PersonAlised Care Team (D-PACT) project as an example, we illustrate how professional stakeholder work can serve various functions, from understanding commissioning and policy context to contributing to detail of intervention components. Outcome: We argue that identifying these project-specific functions can help researchers to effectively plan when, how and for whom they will engage in professional stakeholder work across the course of an evaluation. In addition, we call for further evidence-based guidance and sufficient allocation of …

Digital Cognitive Behavioral Therapy Vs Education For Pain In Adults With Sickle Cell Disease, Charles R. Jonassaint, Christina M. Lalama, C. Patrick Carroll, Sherif M. Badawy, Megan E. Hamm, Jennifer N. Stinson, Chitra Lalloo, Santosh L. Saraf, Victor R. Gordeuk, Robert M. Cronin, Nirmish Shah, Sophie M. Lanzkron, Darla Liles, Julia A. O'Brien, Cassandra Trimnell, Lakiea Bailey, Raymona H. Lawrence, Leshana Saint Jean, Michael Debaun, Laura M. De Castro, Tonya M. Palermo, Kaleab Z. Abebe

Department of Medicine Faculty Papers

Despite the burden of chronic pain in sickle cell disease (SCD), nonpharmacological approaches remain limited. This multisite, randomized trial compared digital cognitive behavioral therapy (CBT) with a digital pain/SCD education program ("Education") for managing pain and related symptoms. Participants were recruited virtually from seven SCD centers and community organizations in the United States. Adults (aged ≥18 years) with SCD-related chronic pain and/or daily opioid use were assigned to receive either CBT or Education for 12 weeks. Both groups used an app with interactive chatbot lessons and received personalized health coach support. The primary outcome was the change in pain interference …

Emata: A Toolbox For The Automatic Extraction And Modeling Of Arterial Inputs For Tracer Kinetic Analysis In [18f]Fdg Brain Studies, Mattia De Francisci, Erica Silvestri, Andrea Bettinelli, Tommaso Volpi, Manu S Goyal, Andrei G Vlassenko, Diego Cecchin, Alessandra Bertoldo

2020-Current year OA Pubs

PURPOSE: PET imaging is a pivotal tool for biomarker research aimed at personalized medicine. Leveraging the quantitative nature of PET requires knowledge of plasma radiotracer concentration. Typically, the arterial input function (AIF) is obtained through arterial cannulation, an invasive and technically demanding procedure. A less invasive alternative, especially for [

METHODS: To assess the toolbox generalizability and present example outputs, EMATA was applied to brain [

RESULTS: EMATA consistently performs IDIF extraction across all datasets, despite differences in scanners and acquisition protocols. Remarkably high agreement is observed when comparing Patlak's K

CONCLUSION: EMATA proved adaptability to different datasets characteristics and …

From The Ocean To Our Kitchen Table: Anthropogenic Particles In The Edible Tissue Of U.S.. West Coast Seafood Species, Summer D. Traylor, Elise F. Granek, Marilyn Duncan, Susanne Brander

Environmental Science and Management Faculty Publications and Presentations

Microplastics (MPs) and other anthropogenic particles (APs) are pervasive environmental contaminants found throughout marine and aquatic environments. We quantified APs in the edible tissue of black rockfish, lingcod, Chinook salmon, Pacific herring, Pacific lamprey, and pink shrimp, comparing AP burdens across trophic levels and between vessel-retrieved and retail-purchased individuals. Edible tissue was digested and analyzed under a microscope, and a subset of suspected APs was identified using spectroscopy (μFTIR). Anthropogenic particles were found in 180 of 182 individuals. Finfish contained 0.02–1.08 AP/g of muscle tissue. In pink shrimp (Pandalus jordani), the average AP/g was 10.68 for vessel-retrieved and …

Loss Of Chop Prevents Joint Degeneration And Pain In A Mouse Model Of Pseudoachondroplasia, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Michele Carrer, Frankie Chiu, Dorde Relic, Paymaan Jafar-Nejad, Karen L Posey

2020-Current year OA Pubs

Pseudoachondroplasia (PSACH), a severe dwarfing condition characterized by impaired skeletal growth and early joint degeneration, results from mutations in cartilage oligomeric matrix protein (COMP). These mutations disrupt normal protein folding, leading to the accumulation of misfolded COMP in chondrocytes. The MT-COMP mouse is a murine model of PSACH that expresses D469del human COMP in response to doxycycline and replicates the PSACH chondrocyte and clinical pathology. The basis for the mutant-COMP pathology involves endoplasmic reticulum (ER) stress signaling through the PERK/eIF2α/CHOP pathway. C/EBP homologous protein (CHOP), in conjunction with a TNFα inflammatory process, upregulates mTORC1, hindering autophagy clearance of mutant COMP …

Lower-Intensity Cpx-351 Plus Venetoclax Induction For Adults With Newly Diagnosed Aml Unfit For Intensive Chemotherapy, Geoffrey L Uy, Vinod Pullarkat, Praneeth Baratam, Robert K Stuart, Roland B Walter, Eric S Winer, Qi Wang, Stefan Faderl, Divya Chakravarthy, Diane Menno, Ronald S Cheung, Tara L Lin

2020-Current year OA Pubs

Preclinical data suggest a rationale for combining CPX-351, a dual-drug liposomal encapsulation of daunorubicin and cytarabine, with venetoclax, a B-cell lymphoma-2 inhibitor. This phase 1b study evaluated lower-intensity CPX-351 combined with venetoclax in adults with acute myeloid leukemia (AML) considered unfit/ineligible for intensive chemotherapy. In a dose-exploration phase using a 3+3 design, patients received stepwise dosing of CPX-351 IV on days 1 and 3 plus venetoclax 400 mg orally on days 2 to 21 per cycle to determine the recommended phase 2 dose (RP2D) for this combination. During the expansion phase, additional patients received CPX-351 plus venetoclax at the identified …

Nonprofit Spotlight: Choice Humanitarian, Erica Jensen

Journal of Nonprofit Innovation

No abstract provided.

Research Summaries: Access To Education, Erica Jensen

Journal of Nonprofit Innovation

No abstract provided.

Full Issue: Access To Education, Angie Holzer

Journal of Nonprofit Innovation

No abstract provided.

Effects Of Monetary Policy On Economic Growth: Evidence From Some Developing And Developed Economies, Collins Anosike

Journal of Global Awareness

The study examined the effects of monetary policy on the economic growth of some developing and developed economies. This study selected 33 countries grouped into 11 each as first-group, second-group, and third-group countries and showed how monetary policy has influenced their economic growth in the past 40 years, capturing the economic growth performances before and after the global financial crisis. This study is unique because it captures a broader range of countries compared to previous studies, uses updated data, and shows how monetary policy is transmitted through bank lending and financial intermediation. Furthermore, we use panel data and employ fixed …

Assessing State Laws And Regulations On Radon In Us Childcare Centers, Benjamin Poku, Sayed Hussaini

Journal of Global Awareness

In the US, radon is the second most significant contributor to lung cancer, following smoking. Despite this, there is a notable absence of state-level measures and guidelines aimed at managing and mitigating the risks associated with exposure to radon gas. The objective of this research was to investigate whether state-level laws regarding radon in childcare centers have a correlation with the proportion of counties in each state that fall under radon zone 1 (with levels exceeding 4 pCi/L). The research method was secondary analysis. Data was gathered from multiple sources, including the EPA radon website, academic journals, official state government …

Takaful Insurance Industries In Supporting Sustainable Socio-Economic Development In Indonesia, Fera Widyanata, Rasyida Pertiwi, Ahmad Syathiri

Journal of Global Awareness

Over the past four years, the demand for Takaful (Islamic insurance) among Indonesians has risen. Health Takaful has emerged as the most popular, followed by educational Takaful. Health and education are parts of the Human Development Index (HDI) and are closely related to building a stronger foundation for Indonesia's economic development. This study aims to enhance the Islamic finance ecosystem's impact on achieving SDGs, focusing on health (SDG 3), education (SDG 4), and economic growth (SDG 8), which are crucial for Indonesia's development. It discovers a causal relationship between the takaful industry and improvements in the health sector and …

The Mediation Of Financial Behavior To Financial Literacy And Spending Habits Of Gen Z: An Exploratory Factor Analysis, Joel Mark Rodriguez, Del Carmen Labong, Lourdes Palallos

Journal of Global Awareness

The study aims to explain the relationship of financial literacy with spending habits and behavior. Financial behavior is a mediator of Generation Z. Financial literacy is a very important dimension in making financial decisions, and this research highlighted the direct and indirect impacts that financial literacy exerts on spending behavior. Data is collected from 317 respondents using a structured questionnaire measuring financial literacy, financial behavior, and spending behavior. Correlation, regression, mediation analysis, and Structural Equation Modeling have been used in evaluating these relationships. Financial literacy directly reflects a strong relationship with spending behavior, and its coefficient is 1.167. Financial behavior, …

Notes From The Editor, Jay Nathan

Journal of Global Awareness

No abstract provided.